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Kohei Miyazono

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
55
Heldin, Carl-Henrik
51
Imamura, Takeshi
25
Kawabata, M
25
ten Dijke, Peter
23
Miyazawa, Keiji
20
Saitoh, Masao
18
Watabe, Tetsuro
14
Ichijo, Hidenori
13
Chiba, Shigeru
12
Morishita, Yasuyuki
10
Kano, Mitsunobu
9
Hanyu, Aki
9
Tojo, Arinobu
8
Hanai, JI
8
Hellman, Ulf

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Publications

TOP 3
Ikushima Hiroaki; Todo Tomoki; Ino Yasushi; Takahashi Masamichi; Miyazawa Keiji; Miyazono Kohei
Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors.
Harada Kaori; Yamazaki Tomoko; Iwata Caname; Yoshimatsu Yasuhiro; Sase Hitoshi; Mishima Koichi; Morishita Yasuyuki; Hirashima Masanori; Oike Yuichi; Suda Toshio; Miura Naoyuki; Watabe Tetsuro; Miyazono Kohei
Identification of targets of Prox1 during in vitro vascular differentiation from embryonic stem cells: functional roles of HoxD8 in lymphangiogenesis.
Koinuma Daizo; Tsutsumi Shuichi; Kamimura Naoko; Imamura Takeshi; Aburatani Hiroyuki; Miyazono Kohei
Promoter-wide analysis of Smad4 binding sites in human epithelial cells.

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All Publications

2009: Ikushima Hiroaki; Todo Tomoki; Ino Yasushi; Takahashi Masamichi; Miyazawa Keiji; Miyazono Kohei
Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors.
Cell stem cell 2009;5(5):504-14.
2009: Harada Kaori; Yamazaki Tomoko; Iwata Caname; Yoshimatsu Yasuhiro; Sase Hitoshi; Mishima Koichi; Morishita Yasuyuki; Hirashima Masanori; Oike Yuichi; Suda Toshio; Miura Naoyuki; Watabe Tetsuro; Miyazono Kohei
Identification of targets of Prox1 during in vitro vascular differentiation from embryonic stem cells: functional roles of HoxD8 in lymphangiogenesis.
Journal of cell science 2009;122(Pt 21):3923-30.
2009: Koinuma Daizo; Tsutsumi Shuichi; Kamimura Naoko; Imamura Takeshi; Aburatani Hiroyuki; Miyazono Kohei
Promoter-wide analysis of Smad4 binding sites in human epithelial cells.
Cancer science 2009;100(11):2133-42.
2009: Kiyono Kunihiko; Suzuki Hiroshi I; Morishita Yasuyuki; Komuro Akiyoshi; Iwata Caname; Yashiro Masakazu; Hirakawa Kosei; Kano Mitsunobu R; Miyazono Kohei
c-Ski overexpression promotes tumor growth and angiogenesis through inhibition of transforming growth factor-beta signaling in diffuse-type gastric carcinoma.
Cancer science 2009;100(10):1809-16.
2009: Sase Hitoshi; Watabe Tetsuro; Kawasaki Kyoko; Miyazono Kohei; Miyazawa Keiji
VEGFR2-PLCgamma1 axis is essential for endothelial specification of VEGFR2+ vascular progenitor cells.
Journal of cell science 2009;122(Pt 18):3303-11.
2009: Suzuki Hiroshi I; Yamagata Kaoru; Sugimoto Koichi; Iwamoto Takashi; Kato Shigeaki; Miyazono Kohei
Modulation of microRNA processing by p53.
Nature 2009;460(7254):529-33.
2009: Komuro Akiyoshi; Yashiro Masakazu; Iwata Caname; Morishita Yasuyuki; Johansson Erik; Matsumoto Yoshiko; Watanabe Akira; Aburatani Hiroyuki; Miyoshi Hiroyuki; Kiyono Kunihiko; Shirai Yo-taro; Suzuki Hiroshi I; Hirakawa Kosei; Kano Mitsunobu R; Miyazono Kohei
Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling.
Journal of the National Cancer Institute 2009;101(8):592-604.
2009: Saito Roy-Akira; Watabe Tetsuro; Horiguchi Kana; Kohyama Tadashi; Saitoh Masao; Nagase Takahide; Miyazono Kohei
Thyroid transcription factor-1 inhibits transforming growth factor-beta-mediated epithelial-to-mesenchymal transition in lung adenocarcinoma cells.
Cancer research 2009;69(7):2783-91.
2009: Saitoh Masao; Shirakihara Takuya; Miyazono Kohei
Regulation of the stability of cell surface E-cadherin by the proteasome.
Biochemical and biophysical research communications 2009;381(4):560-5.
2009: Miyai Kentaro; Yoneda Mitsuhiro; Hasegawa Urara; Toita Sayaka; Izu Yayoi; Hemmi Hiroaki; Hayata Tadayoshi; Ezura Yoichi; Mizutani Shuki; Miyazono Kohei; Akiyoshi Kazunari; Yamamoto Tadashi; Noda Masaki
ANA deficiency enhances bone morphogenetic protein-induced ectopic bone formation via transcriptional events.
The Journal of biological chemistry 2009;284(16):10593-600.
2009: Yamazaki Tomoko; Yoshimatsu Yasuhiro; Morishita Yasuyuki; Miyazono Kohei; Watabe Tetsuro
COUP-TFII regulates the functions of Prox1 in lymphatic endothelial cells through direct interaction.
Genes to cells : devoted to molecular & cellular mechanisms 2009;14(3):425-34.
2009: Watabe Tetsuro; Miyazono Kohei
Roles of TGF-beta family signaling in stem cell renewal and differentiation.
Cell research 2009;19(1):103-15.
2009: Kano Mitsunobu R; Komuta Yukari; Iwata Caname; Oka Masako; Shirai Yo-taro; Morishita Yasuyuki; Ouchi Yasuyoshi; Kataoka Kazunori; Miyazono Kohei
Comparison of the effects of the kinase inhibitors imatinib, sorafenib, and transforming growth factor-beta receptor inhibitor on extravasation of nanoparticles from neovasculature.
Cancer science 2009;100(1):173-80.
2009: Horiguchi Kana; Shirakihara Takuya; Nakano Ayako; Imamura Takeshi; Miyazono Kohei; Saitoh Masao
Role of Ras signaling in the induction of snail by transforming growth factor-beta.
The Journal of biological chemistry 2009;284(1):245-53.
2009: Miyazono Kohei
Transforming growth factor-beta signaling in epithelial-mesenchymal transition and progression of cancer.
Proceedings of the Japan Academy. Series B, Physical and biological sciences 2009;85(8):314-23.
2009: Tominaga Hiroyuki; Maeda Shingo; Miyoshi Hiroyuki; Miyazono Kohei; Komiya Setsuro; Imamura Takeshi
Expression of osterix inhibits bone morphogenetic protein-induced chondrogenic differentiation of mesenchymal progenitor cells.
Journal of bone and mineral metabolism 2009;27(1):36-45.
2008: Fukuda Toru; Kanomata Kazuhiro; Nojima Junya; Kokabu Shoichiro; Akita Masumi; Ikebuchi Kenji; Jimi Eijiro; Komori Tetsuo; Maruki Yuichi; Matsuoka Masaru; Miyazono Kohei; Nakayama Konosuke; Nanba Akira; Tomoda Hiroshi; Okazaki Yasushi; Ohtake Akira; Oda Hiromi; Owan Ichiro; Yoda Tetsuya; Haga Nobuhiko; Furuya Hirokazu; Katagiri Takenobu
A unique mutation of ALK2, G356D, found in a patient with fibrodysplasia ossificans progressiva is a moderately activated BMP type I receptor.
Biochemical and biophysical research communications 2008;377(3):905-9.
2008: Miyata Kanjiro; Oba Makoto; Kano Mitsunobu R; Fukushima Shigeto; Vachutinsky Yelena; Han Muri; Koyama Hiroyuki; Miyazono Kohei; Nishiyama Nobuhiro; Kataoka Kazunori
Polyplex micelles from triblock copolymers composed of tandemly aligned segments with biocompatible, endosomal escaping, and DNA-condensing functions for systemic gene delivery to pancreatic tumor tissue.
Pharmaceutical research 2008;25(12):2924-36.
2008: Miyazono Kohei
Shear activates platelet-derived latent TGF-beta.
Blood 2008;112(9):3533-4.
2008: Ikushima Hiroaki; Komuro Akiyoshi; Isogaya Kazunobu; Shinozaki Masahiko; Hellman Ulf; Miyazawa Keiji; Miyazono Kohei
An Id-like molecule, HHM, is a synexpression group-restricted regulator of TGF-beta signalling.
The EMBO journal 2008;27(22):2955-65.
2008: Kokudo Takashi; Suzuki Yuka; Yoshimatsu Yasuhiro; Yamazaki Tomoko; Watabe Tetsuro; Miyazono Kohei
Snail is required for TGFbeta-induced endothelial-mesenchymal transition of embryonic stem cell-derived endothelial cells.
Journal of cell science 2008;121(Pt 20):3317-24.
2008: Nonaka Hidenori; Watabe Tetsuro; Saito Shigeru; Miyazono Kohei; Miyajima Atsushi
Development of stabilin2+ endothelial cells from mouse embryonic stem cells by inhibition of TGFbeta/activin signaling.
Biochemical and biophysical research communications 2008;375(2):256-60.
2008: Katsuno Y; Hanyu A; Kanda H; Ishikawa Y; Akiyama F; Iwase T; Ogata E; Ehata S; Miyazono K; Imamura T
Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway.
Oncogene 2008;27(49):6322-33.
2008: Kamiya Yuto; Miyazono Kohei; Miyazawa Keiji
Specificity of the inhibitory effects of Dad on TGF-beta family type I receptors, Thickveins, Saxophone, and Baboon in Drosophila.
FEBS letters 2008;582(17):2496-500.
2008: Wu Shourong; Nishiyama Nobuhiro; Kano Mitsunobu R; Morishita Yasuyuki; Miyazono Kohei; Itaka Keiji; Chung Ung-Il; Kataoka Kazunori
Enhancement of angiogenesis through stabilization of hypoxia-inducible factor-1 by silencing prolyl hydroxylase domain-2 gene.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(7):1227-34.
2008: Miyazono Kohei; Kamiya Yuto; Miyazawa Keiji
SUMO amplifies TGF-beta signalling.
Nature cell biology 2008;10(6):635-7.
2008: Monzen Koshiro; Ito Yuzuru; Naito Atsuhiko T; Kasai Hiroki; Hiroi Yukio; Hayashi Doubun; Shiojima Ichiro; Yamazaki Tsutomu; Miyazono Kohei; Asashima Makoto; Nagai Ryozo; Komuro Issei
A crucial role of a high mobility group protein HMGA2 in cardiogenesis.
Nature cell biology 2008;10(5):567-74.
2008: Oka Masako; Iwata Caname; Suzuki Hiroshi I; Kiyono Kunihiko; Morishita Yasuyuki; Watabe Tetsuro; Komuro Akiyoshi; Kano Mitsunobu R; Miyazono Kohei
Inhibition of endogenous TGF-beta signaling enhances lymphangiogenesis.
Blood 2008;111(9):4571-9.
2008: Kawasaki Kyoko; Watabe Tetsuro; Sase Hitoshi; Hirashima Masanori; Koide Hiroshi; Morishita Yasuyuki; Yuki Keiko; Sasaoka Toshikuni; Suda Toshio; Katsuki Motoya; Miyazono Kohei; Miyazawa Keiji
Ras signaling directs endothelial specification of VEGFR2+ vascular progenitor cells.
The Journal of cell biology 2008;181(1):131-41.
2008: Asagiri Masataka; Hirai Toshitake; Kunigami Toshihiro; Kamano Shunya; Gober Hans-Jürgen; Okamoto Kazuo; Nishikawa Keizo; Latz Eicke; Golenbock Douglas T; Aoki Kazuhiro; Ohya Keiichi; Imai Yuuki; Morishita Yasuyuki; Miyazono Kohei; Kato Shigeaki; Saftig Paul; Takayanagi Hiroshi
Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis.
Science (New York, N.Y.) 2008;319(5863):624-7.
2008: Suzuki Yuka; Montagne Kevin; Nishihara Ayako; Watabe Tetsuro; Miyazono Kohei
BMPs promote proliferation and migration of endothelial cells via stimulation of VEGF-A/VEGFR2 and angiopoietin-1/Tie2 signalling.
Journal of biochemistry 2008;143(2):199-206.
2008: Hayashi Makoto; Maeda Shingo; Aburatani Hiroyuki; Kitamura Kunio; Miyoshi Hiroyuki; Miyazono Kohei; Imamura Takeshi
Pitx2 prevents osteoblastic transdifferentiation of myoblasts by bone morphogenetic proteins.
The Journal of biological chemistry 2008;283(1):565-71.
2007: Iwata Caname; Kano Mitsunobu R; Komuro Akiyoshi; Oka Masako; Kiyono Kunihiko; Johansson Erik; Morishita Yasuyuki; Yashiro Masakazu; Hirakawa Kosei; Kaminishi Michio; Miyazono Kohei
Inhibition of cyclooxygenase-2 suppresses lymph node metastasis via reduction of lymphangiogenesis.
Cancer research 2007;67(21):10181-9.
2007: Ehata Shogo; Hanyu Aki; Hayashi Makoto; Aburatani Hiroyuki; Kato Yukio; Fujime Makoto; Saitoh Masao; Miyazawa Keiji; Imamura Takeshi; Miyazono Kohei
Transforming growth factor-beta promotes survival of mammary carcinoma cells through induction of antiapoptotic transcription factor DEC1.
Cancer research 2007;67(20):9694-703.
2007: Shirakihara Takuya; Saitoh Masao; Miyazono Kohei
Differential regulation of epithelial and mesenchymal markers by deltaEF1 proteins in epithelial mesenchymal transition induced by TGF-beta.
Molecular biology of the cell 2007;18(9):3533-44.
2007: Nakagome Kazuyuki; Dohi Makoto; Okunishi Katsuhide; Tanaka Ryoichi; Kouro Taku; Kano Mitsunobu R; Miyazono Kohei; Miyazaki Jun-ichi; Takatsu Kiyoshi; Yamamoto Kazuhiko
IL-5-induced hypereosinophilia suppresses the antigen-induced immune response via a TGF-beta-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(1):284-94.
2007: Nagano Yoshiko; Mavrakis Konstantinos J; Lee Kian Leong; Fujii Tomoko; Koinuma Daizo; Sase Hitoshi; Yuki Keiko; Isogaya Kazunobu; Saitoh Masao; Imamura Takeshi; Episkopou Vasso; Miyazono Kohei; Miyazawa Keiji
Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling.
The Journal of biological chemistry 2007;282(28):20492-501.
2007: Goto Kouichiro; Kamiya Yuto; Imamura Takeshi; Miyazono Kohei; Miyazawa Keiji
Selective inhibitory effects of Smad6 on bone morphogenetic protein type I receptors.
The Journal of biological chemistry 2007;282(28):20603-11.
2007: Shimanuki T; Hara T; Furuya T; Imamura T; Miyazono K
Modulation of the functional binding sites for TGF-beta on the type II receptor leads to suppression of TGF-beta signaling.
Oncogene 2007;26(23):3311-20.
2007: Saita Yoshitomo; Takagi Tsuyoshi; Kitahara Keiichiro; Usui Michihiko; Miyazono Kohei; Ezura Yoichi; Nakashima Kazuhisa; Kurosawa Hisashi; Ishii Shunsuke; Noda Masaki
Lack of Schnurri-2 expression associates with reduced bone remodeling and osteopenia.
The Journal of biological chemistry 2007;282(17):12907-15.
2007: Mishima Koichi; Watabe Tetsuro; Saito Akira; Yoshimatsu Yasuhiro; Imaizumi Natsuko; Masui Shinji; Hirashima Masanori; Morisada Tohru; Oike Yuichi; Araie Makoto; Niwa Hitoshi; Kubo Hajime; Suda Toshio; Miyazono Kohei
Prox1 induces lymphatic endothelial differentiation via integrin alpha9 and other signaling cascades.
Molecular biology of the cell 2007;18(4):1421-9.
2007: Kobayashi Norihiko; Goto Kouichiro; Horiguchi Kana; Nagata Motoko; Kawata Mikiko; Miyazawa Keiji; Saitoh Masao; Miyazono Kohei
c-Ski activates MyoD in the nucleus of myoblastic cells through suppression of histone deacetylases.
Genes to cells : devoted to molecular & cellular mechanisms 2007;12(3):375-85.
2007: Kano Mitsunobu R; Bae Younsoo; Iwata Caname; Morishita Yasuyuki; Yashiro Masakazu; Oka Masako; Fujii Tomoko; Komuro Akiyoshi; Kiyono Kunihiko; Kaminishi Michio; Hirakawa Kosei; Ouchi Yasuyoshi; Nishiyama Nobuhiro; Kataoka Kazunori; Miyazono Kohei
Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3460-5.
2007: Ehata Shogo; Hanyu Aki; Fujime Makoto; Katsuno Yoko; Fukunaga Erina; Goto Kouichiro; Ishikawa Yuichi; Nomura Kimie; Yokoo Hiroshi; Shimizu Toshiyuki; Ogata Etsuro; Miyazono Kohei; Shimizu Kiyoshi; Imamura Takeshi
Ki26894, a novel transforming growth factor-beta type I receptor kinase inhibitor, inhibits in vitro invasion and in vivo bone metastasis of a human breast cancer cell line.
Cancer science 2007;98(1):127-33.
2006: Nagata Motoko; Goto Kouichiro; Ehata Shogo; Kobayashi Norihiko; Saitoh Masao; Miyoshi Hiroyuki; Imamura Takeshi; Miyazawa Keiji; Miyazono Kohei
Nuclear and cytoplasmic c-Ski differently modulate cellular functions.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(11):1267-80.
2006: Shirakawa Ken; Maeda Shingo; Gotoh Tomomi; Hayashi Makoto; Shinomiya Kenichi; Ehata Shogo; Nishimura Riko; Mori Masataka; Onozaki Kikuo; Hayashi Hidetoshi; Uematsu Satoshi; Akira Shizuo; Ogata Etsuro; Miyazono Kohei; Imamura Takeshi
CCAAT/enhancer-binding protein homologous protein (CHOP) regulates osteoblast differentiation.
Molecular and cellular biology 2006;26(16):6105-16.
2006: Fukuda N; Saitoh M; Kobayashi N; Miyazono K
Execution of BMP-4-induced apoptosis by p53-dependent ER dysfunction in myeloma and B-cell hybridoma cells.
Oncogene 2006;25(25):3509-17.
2006: Miyazono Kohei; Ishikawa Fuyuki; Winterhager Elke; Deppert Wolfgang; Rajewsky Manfred F
Tenth Japanese-German Workshop on Molecular and Cellular Aspects of Carcinogenesis, Essen, Germany, 29 September-1 October 2005.
Cancer science 2006;97(4):332-9.
2006: Watabe Tetsuro; Yamashita Jun K; Mishima Koichi; Miyazono Kohei
TGF-beta signaling in embryonic stem cell-derived endothelial cells.
Methods in molecular biology (Clifton, N.J.) 2006;330():341-51.
2005: Tojo Masayoshi; Hamashima Yoshio; Hanyu Aki; Kajimoto Tetsuya; Saitoh Masao; Miyazono Kohei; Node Manabu; Imamura Takeshi
The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-beta.
Cancer science 2005;96(11):791-800.
2005: Hayashi Makoto; Imamura Takeshi; Miyazono Kohei
[BMP receptors and signal transduction]
Nippon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 10():399-403.
2005: Kano Mitsunobu R; Morishita Yasuyuki; Iwata Caname; Iwasaka Shigeru; Watabe Tetsuro; Ouchi Yasuyoshi; Miyazono Kohei; Miyazawa Keiji
VEGF-A and FGF-2 synergistically promote neoangiogenesis through enhancement of endogenous PDGF-B-PDGFRbeta signaling.
Journal of cell science 2005;118(Pt 16):3759-68.
2005: Miyazono Kohei; Maeda Shingo; Imamura Takeshi
BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk.
Cytokine & growth factor reviews 2005;16(3):251-63.
2005: Morén Anita; Imamura Takeshi; Miyazono Kohei; Heldin Carl-Henrik; Moustakas Aristidis
Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases.
The Journal of biological chemistry 2005;280(23):22115-23.
2005: Kahata Kaoru; Asaka Masahiro; Miyazono Kohei
[TGF-beta signaling and carcinogenesis]
Nippon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 4():549-54.
2005: Koinuma Daizo; Imamura Takeshi; Miyazono Kohei
[TGF-beta family (TGF-beta, activin, BMP)]
Nippon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 4():215-9.
2005: Yamamoto Kimiko; Sokabe Takaaki; Watabe Tetsuro; Miyazono Kohei; Yamashita Jun K; Obi Syotaro; Ohura Norihiko; Matsushita Akiko; Kamiya Akira; Ando Joji
Fluid shear stress induces differentiation of Flk-1-positive embryonic stem cells into vascular endothelial cells in vitro.
American journal of physiology. Heart and circulatory physiology 2005;288(4):H1915-24.
2005: Kawazu Masahito; Asai Takashi; Ichikawa Motoshi; Yamamoto Go; Saito Toshiki; Goyama Susumu; Mitani Kinuko; Miyazono Kohei; Chiba Shigeru; Ogawa Seishi; Kurokawa Mineo; Hirai Hisamaru
Functional domains of Runx1 are differentially required for CD4 repression, TCRbeta expression, and CD4/8 double-negative to CD4/8 double-positive transition in thymocyte development.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(6):3526-33.
2005: Suzuki Hiroyuki; Watabe Tetsuro; Kato Mitsuyasu; Miyazawa Keiji; Miyazono Kohei
Roles of vascular endothelial growth factor receptor 3 signaling in differentiation of mouse embryonic stem cell-derived vascular progenitor cells into endothelial cells.
Blood 2005;105(6):2372-9.
2005: Kuratomi Go; Komuro Akiyoshi; Goto Kouichiro; Shinozaki Masahiko; Miyazawa Keiji; Miyazono Kohei; Imamura Takeshi
NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.
The Biochemical journal 2005;386(Pt 3):461-70.
2004: Miyazaki Hideyo; Watabe Tetsuro; Kitamura Tadaichi; Miyazono Kohei
BMP signals inhibit proliferation and in vivo tumor growth of androgen-insensitive prostate carcinoma cells.
Oncogene 2004;23(58):9326-35.
2004: Kondo M; Cubillo E; Tobiume K; Shirakihara T; Fukuda N; Suzuki H; Shimizu K; Takehara K; Cano A; Saitoh M; Miyazono K
A role for Id in the regulation of TGF-beta-induced epithelial-mesenchymal transdifferentiation.
Cell death and differentiation 2004;11(10):1092-101.
2004: Komuro Akiyoshi; Imamura Takeshi; Saitoh Masao; Yoshida Yoko; Yamori Takao; Miyazono Kohei; Miyazawa Keiji
Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1).
Oncogene 2004;23(41):6914-23.
2004: Ikeda Yuichi; Imai Yasushi; Kumagai Hidetoshi; Nosaka Tetsuya; Morikawa Yoshihiro; Hisaoka Tomoko; Manabe Ichiro; Maemura Koji; Nakaoka Takashi; Imamura Takeshi; Miyazono Kohei; Komuro Issei; Nagai Ryozo; Kitamura Toshio
Vasorin, a transforming growth factor beta-binding protein expressed in vascular smooth muscle cells, modulates the arterial response to injury in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(29):10732-7.
2004: Mochizuki Toshiaki; Miyazaki Hideyo; Hara Takane; Furuya Toshio; Imamura Takeshi; Watabe Tetsuro; Miyazono Kohei
Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-beta superfamily signaling.
The Journal of biological chemistry 2004;279(30):31568-74.
2004: Suzuki Hiroyuki; Yagi Ken; Kondo Miki; Kato Mitsuyasu; Miyazono Kohei; Miyazawa Keiji
c-Ski inhibits the TGF-beta signaling pathway through stabilization of inactive Smad complexes on Smad-binding elements.
Oncogene 2004;23(29):5068-76.
2004: Miyazono Kohei; Maeda Shingo; Imamura Takeshi
Coordinate regulation of cell growth and differentiation by TGF-beta superfamily and Runx proteins.
Oncogene 2004;23(24):4232-7.
2004: Usui Michihiko; Yoshida Yutaka; Tsuji Kunikazu; Oikawa Kaoru; Miyazono Kohei; Ishikawa Isao; Yamamoto Tadashi; Nifuji Akira; Noda Masaki
Tob deficiency superenhances osteoblastic activity after ovariectomy to block estrogen deficiency-induced osteoporosis.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(17):6653-8.
2004: Miyazono Kohei; Ishikawa Fuyuki; Winterhager Elke; Deppert Wolfgang; Rajewsky Manfred F
Ninth Japanese-German Workshop on Molecular and Cellular Aspects of Carcinogenesis, Essen, Germany, 18-20 September, 2003.
Cancer science 2004;95(3):276-81.
2004: Takeda Masafumi; Mizuide Masafumi; Oka Masako; Watabe Tetsuro; Inoue Hirofumi; Suzuki Hiroyuki; Fujita Toshiro; Imamura Takeshi; Miyazono Kohei; Miyazawa Keiji
Interaction with Smad4 is indispensable for suppression of BMP signaling by c-Ski.
Molecular biology of the cell 2004;15(3):963-72.
2004: Kahata Kaoru; Hayashi Makoto; Asaka Masahiro; Hellman Ulf; Kitagawa Hirochika; Yanagisawa Jun; Kato Shigeaki; Imamura Takeshi; Miyazono Kohei
Regulation of transforming growth factor-beta and bone morphogenetic protein signalling by transcriptional coactivator GCN5.
Genes to cells : devoted to molecular & cellular mechanisms 2004;9(2):143-51.
2004: Ijichi Hideaki; Otsuka Motoyuki; Tateishi Keisuke; Ikenoue Tsuneo; Kawakami Takayuki; Kanai Fumihiko; Arakawa Yoshihiro; Seki Naohiko; Shimizu Kiyoshi; Miyazono Kohei; Kawabe Takao; Omata Masao
Smad4-independent regulation of p21/WAF1 by transforming growth factor-beta.
Oncogene 2004;23(5):1043-51.
2004: Maeda Shingo; Hayashi Makoto; Komiya Setsuro; Imamura Takeshi; Miyazono Kohei
Endogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cells.
The EMBO journal 2004;23(3):552-63.
2004: Kondo Miki; Suzuki Hiroyuki; Takehara Kazuhiko; Miyazono Kohei; Kato Mitsuyasu
Transforming growth factor-beta signaling is differentially inhibited by Smad2D450E and Smad3D407E.
Cancer science 2004;95(1):12-7.
2003: Watabe Tetsuro; Nishihara Ayako; Mishima Koichi; Yamashita Jun; Shimizu Kiyoshi; Miyazawa Keiji; Nishikawa Shin-Ichi; Miyazono Kohei
TGF-beta receptor kinase inhibitor enhances growth and integrity of embryonic stem cell-derived endothelial cells.
The Journal of cell biology 2003;163(6):1303-11.
2003: Koinuma Daizo; Shinozaki Masahiko; Komuro Akiyoshi; Goto Kouichiro; Saitoh Masao; Hanyu Aki; Ebina Masahito; Nukiwa Toshihiro; Miyazawa Keiji; Imamura Takeshi; Miyazono Kohei
Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7.
The EMBO journal 2003;22(24):6458-70.
2003: Matsuyama Shigeo; Iwadate Manabu; Kondo Miki; Saitoh Masao; Hanyu Aki; Shimizu Kiyoshi; Aburatani Hiroyuki; Mishima Hiromu K; Imamura Takeshi; Miyazono Kohei; Miyazawa Keiji
SB-431542 and Gleevec inhibit transforming growth factor-beta-induced proliferation of human osteosarcoma cells.
Cancer research 2003;63(22):7791-8.
2003: Murakami Gyo; Watabe Tetsuro; Takaoka Kunio; Miyazono Kohei; Imamura Takeshi
Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads.
Molecular biology of the cell 2003;14(7):2809-17.
2003: Yoshida Yutaka; von Bubnoff Andreas; Ikematsu Naoko; Blitz Ira L; Tsuzuku Junko K; Yoshida Eri H; Umemori Hisashi; Miyazono Kohei; Yamamoto Tadashi; Cho Ken W Y
Tob proteins enhance inhibitory Smad-receptor interactions to repress BMP signaling.
Mechanisms of development 2003;120(5):629-37.
2003: Nakayama Konosuke; Tamura Yasuhiro; Suzawa Miyuki; Harada Shun-Ichi; Fukumoto Seiji; Kato Mitsuyasu; Miyazono Kohei; Rodan Gideon A; Takeuchi Yasuhiro; Fujita Toshiro
Receptor tyrosine kinases inhibit bone morphogenetic protein-Smad responsive promoter activity and differentiation of murine MC3T3-E1 osteoblast-like cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(5):827-35.
2003: Miyazono Kohei; Suzuki Hiroyuki; Imamura Takeshi
Regulation of TGF-beta signaling and its roles in progression of tumors.
Cancer science 2003;94(3):230-4.
2003: Tajima Yoshitaka; Goto Kouichiro; Yoshida Minoru; Shinomiya Kenichi; Sekimoto Toshihiro; Yoneda Yoshihiro; Miyazono Kohei; Imamura Takeshi
Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7.
The Journal of biological chemistry 2003;278(12):10716-21.
2003: Sasaki Toru; Suzuki Hiroyuki; Yagi Ken; Furuhashi Masao; Yao Ryoji; Susa Shinji; Noda Tetsuo; Arai Yoichi; Miyazono Kohei; Kato Mitsuyasu
Lymphoid enhancer factor 1 makes cells resistant to transforming growth factor beta-induced repression of c-myc.
Cancer research 2003;63(4):801-6.
2003: Midorikawa Yutaka; Ishikawa Shumpei; Iwanari Hiroko; Imamura Takeshi; Sakamoto Hirohiko; Miyazono Kohei; Kodama Tatsuhiko; Makuuchi Masatoshi; Aburatani Hiroyuki
Glypican-3, overexpressed in hepatocellular carcinoma, modulates FGF2 and BMP-7 signaling.
International journal of cancer. Journal international du cancer 2003;103(4):455-65.
2003: Mizuide Masafumi; Hara Takane; Furuya Toshio; Takeda Masafumi; Kusanagi Kiyoshi; Inada Yuri; Mori Masatomo; Imamura Takeshi; Miyazawa Keiji; Miyazono Kohei
Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN.
The Journal of biological chemistry 2003;278(1):531-6.
2002: Miyazawa Keiji; Shinozaki Masahiko; Hara Takane; Furuya Toshio; Miyazono Kohei
Two major Smad pathways in TGF-beta superfamily signalling.
Genes to cells : devoted to molecular & cellular mechanisms 2002;7(12):1191-204.
2002: Ota Tatsuru; Fujii Makiko; Sugizaki Takashi; Ishii Masami; Miyazawa Keiji; Aburatani Hiroyuki; Miyazono Kohei
Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-beta in human umbilical vein endothelial cells.
Journal of cellular physiology 2002;193(3):299-318.
2002: Miyazono Kohei
Regulation of transforming growth factor-beta signaling and vascular diseases.
Cornea 2002;21(7 Suppl):S48-53.
2002: Suzuki Chie; Murakami Gyo; Fukuchi Minoru; Shimanuki Tomomasa; Shikauchi Yuko; Imamura Takeshi; Miyazono Kohei
Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane.
The Journal of biological chemistry 2002;277(42):39919-25.
2002: Miyazono Kohei; Miyazawa Keiji
Id: a target of BMP signaling.
Science's STKE : signal transduction knowledge environment 2002;2002(151):pe40.
2002: Nishihara Ayako; Watabe Tetsuro; Imamura Takeshi; Miyazono Kohei
Functional heterogeneity of bone morphogenetic protein receptor-II mutants found in patients with primary pulmonary hypertension.
Molecular biology of the cell 2002;13(9):3055-63.
2002: Shen Zhong-Jian; Nakamoto Tetsuya; Tsuji Kunikazu; Nifuji Akira; Miyazono Kohei; Komori Toshihisa; Hirai Hisamaru; Noda Masaki
Negative regulation of bone morphogenetic protein/Smad signaling by Cas-interacting zinc finger protein in osteoblasts.
The Journal of biological chemistry 2002;277(33):29840-6.
2002: Suzawa Miyuki; Tamura Yasuhiro; Fukumoto Seiji; Miyazono Kohei; Fujita Toshiro; Kato Shigeaki; Takeuchi Yasuhiro
Stimulation of Smad1 transcriptional activity by Ras-extracellular signal-regulated kinase pathway: a possible mechanism for collagen-dependent osteoblastic differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(2):240-8.
2002: Miyazono Kohei
A new partner for inhibitory Smads.
Cytokine & growth factor reviews 2002;13(1):7-9.
2002: Yagi Ken; Furuhashi Masao; Aoki Hiromasa; Goto Daisuke; Kuwano Hiroyuki; Sugamura Kazuo; Miyazono Kohei; Kato Mitsuyasu
c-myc is a downstream target of the Smad pathway.
The Journal of biological chemistry 2002;277(1):854-61.
2001: Hanyu A; Ishidou Y; Ebisawa T; Shimanuki T; Imamura T; Miyazono K
The N domain of Smad7 is essential for specific inhibition of transforming growth factor-beta signaling.
The Journal of cell biology 2001;155(6):1017-27.
2001: Tamura Y; Takeuchi Y; Suzawa M; Fukumoto S; Kato M; Miyazono K; Fujita T
Focal adhesion kinase activity is required for bone morphogenetic protein--Smad1 signaling and osteoblastic differentiation in murine MC3T3-E1 cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(10):1772-9.
2001: Yamato K; Hashimoto S; Imamura T; Uchida H; Okahashi N; Koseki T; Ishisaki A; Kizaki M; Miyazono K; Ikeda Y; Nishihara T
Activation of the p21(CIP1/WAF1) promoter by bone morphogenetic protein-2 in mouse B lineage cells.
Oncogene 2001;20(32):4383-92.
2001: Kusanagi K; Kawabata M; Mishima H K; Miyazono K
Alpha-helix 2 in the amino-terminal mad homology 1 domain is responsible for specific DNA binding of Smad3.
The Journal of biological chemistry 2001;276(30):28155-63.
2001: Miyazono K; Kusanagi K; Inoue H
Divergence and convergence of TGF-beta/BMP signaling.
Journal of cellular physiology 2001;187(3):265-76.
2001: Monzen K; Hiroi Y; Kudoh S; Akazawa H; Oka T; Takimoto E; Hayashi D; Hosoda T; Kawabata M; Miyazono K; Ishii S; Yazaki Y; Nagai R; Komuro I
Smads, TAK1, and their common target ATF-2 play a critical role in cardiomyocyte differentiation.
The Journal of cell biology 2001;153(4):687-98.
2001: Ebisawa T; Fukuchi M; Murakami G; Chiba T; Tanaka K; Imamura T; Miyazono K
Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation.
The Journal of biological chemistry 2001;276(16):12477-80.
2001: Tobiume K; Matsuzawa A; Takahashi T; Nishitoh H; Morita K; Takeda K; Minowa O; Miyazono K; Noda T; Ichijo H
ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis.
EMBO reports 2001;2(3):222-8.
2001: Tada Y; Asahina A; Nakamura K; Miyazono K; Tomura M; Fujiwara H; Tamaki K
Transforming growth factor-beta up-regulates CD40-engaged IL-12 production of mouse Langerhans cells.
European journal of immunology 2001;31(1):294-300.
2000: Yoshida Y; Tanaka S; Umemori H; Minowa O; Usui M; Ikematsu N; Hosoda E; Imamura T; Kuno J; Yamashita T; Miyazono K; Noda M; Noda T; Yamamoto T
Negative regulation of BMP/Smad signaling by Tob in osteoblasts.
Cell 2000;103(7):1085-97.
2000: Miyazono K
[Transforming growth factor-beta signaling and cancer]
Human cell : official journal of Human Cell Research Society 2000;13(3):97-101.
2000: Beppu H; Miyazono K
[The roles of TGF-beta superfamily in mouse early development]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(13 Suppl):2109-15.
2000: Udagawa Y; Hanai J; Tada K; Grieder N C; Momoeda M; Taketani Y; Affolter M; Kawabata M; Miyazono K
Schnurri interacts with Mad in a Dpp-dependent manner.
Genes to cells : devoted to molecular & cellular mechanisms 2000;5(5):359-69.
2000: Beppu H; Kawabata M; Hamamoto T; Chytil A; Minowa O; Noda T; Miyazono K
BMP type II receptor is required for gastrulation and early development of mouse embryos.
Developmental biology 2000;221(1):249-58.
2000: Miyazono K
Positive and negative regulation of TGF-beta signaling.
Journal of cell science 2000;113 ( Pt 7)():1101-9.
2000: Miyazono K
TGF-beta signaling by Smad proteins.
Cytokine & growth factor reviews 2000;11(1-2):15-22.
2000: Ishida W; Hamamoto T; Kusanagi K; Yagi K; Kawabata M; Takehara K; Sampath T K; Kato M; Miyazono K
Smad6 is a Smad1/5-induced smad inhibitor. Characterization of bone morphogenetic protein-responsive element in the mouse Smad6 promoter.
The Journal of biological chemistry 2000;275(9):6075-9.
2000: Kusanagi K; Inoue H; Ishidou Y; Mishima H K; Kawabata M; Miyazono K
Characterization of a bone morphogenetic protein-responsive Smad-binding element.
Molecular biology of the cell 2000;11(2):555-65.
2000: ten Dijke P; Miyazono K; Heldin C H
Signaling inputs converge on nuclear effectors in TGF-beta signaling.
Trends in biochemical sciences 2000;25(2):64-70.
2000: Kanamoto T; Mota M; Takeda K; Rubin L L; Miyazono K; Ichijo H; Bazenet C E
Role of apoptosis signal-regulating kinase in regulation of the c-Jun N-terminal kinase pathway and apoptosis in sympathetic neurons.
Molecular and cellular biology 2000;20(1):196-204.
2000: Miyazono K; ten Dijke P; Heldin C H
TGF-beta signaling by Smad proteins.
Advances in immunology 2000;75():115-57.
1999: Tada K; Inoue H; Ebisawa T; Makuuchi M; Kawabata M; Imamura T; Miyazono K
Region between alpha-helices 3 and 4 of the mad homology 2 domain of Smad4: functional roles in oligomer formation and transcriptional activation.
Genes to cells : devoted to molecular & cellular mechanisms 1999;4(12):731-41.
1999: Akiyoshi S; Inoue H; Hanai J; Kusanagi K; Nemoto N; Miyazono K; Kawabata M
c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads.
The Journal of biological chemistry 1999;274(49):35269-77.
1999: Fujii M; Takeda K; Imamura T; Aoki H; Sampath T K; Enomoto S; Kawabata M; Kato M; Ichijo H; Miyazono K
Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation.
Molecular biology of the cell 1999;10(11):3801-13.
1999: Hanai J; Chen L F; Kanno T; Ohtani-Fujita N; Kim W Y; Guo W H; Imamura T; Ishidou Y; Fukuchi M; Shi M J; Stavnezer J; Kawabata M; Miyazono K; Ito Y
Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter.
The Journal of biological chemistry 1999;274(44):31577-82.
1999: Ebisawa T; Tada K; Kitajima I; Tojo K; Sampath T K; Kawabata M; Miyazono K; Imamura T
Characterization of bone morphogenetic protein-6 signaling pathways in osteoblast differentiation.
Journal of cell science 1999;112 ( Pt 20)():3519-27.
1999: Nishihara A; Hanai J; Imamura T; Miyazono K; Kawabata M
E1A inhibits transforming growth factor-beta signaling through binding to Smad proteins.
The Journal of biological chemistry 1999;274(40):28716-23.
1999: Miyazono K
Signal transduction by bone morphogenetic protein receptors: functional roles of Smad proteins.
Bone 1999;25(1):91-3.
1999: Yanagi Y; Suzawa M; Kawabata M; Miyazono K; Yanagisawa J; Kato S
Positive and negative modulation of vitamin D receptor function by transforming growth factor-beta signaling through smad proteins.
The Journal of biological chemistry 1999;274(19):12971-4.
1999: Suzawa M; Takeuchi Y; Fukumoto S; Kato S; Ueno N; Miyazono K; Matsumoto T; Fujita T
Extracellular matrix-associated bone morphogenetic proteins are essential for differentiation of murine osteoblastic cells in vitro.
Endocrinology 1999;140(5):2125-33.
1999: Nakashima K; Yanagisawa M; Arakawa H; Kimura N; Hisatsune T; Kawabata M; Miyazono K; Taga T
Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300.
Science (New York, N.Y.) 1999;284(5413):479-82.
1999: Yanagisawa J; Yanagi Y; Masuhiro Y; Suzawa M; Watanabe M; Kashiwagi K; Toriyabe T; Kawabata M; Miyazono K; Kato S
Convergence of transforming growth factor-beta and vitamin D signaling pathways on SMAD transcriptional coactivators.
Science (New York, N.Y.) 1999;283(5406):1317-21.
1999: Yamashita H; Miyazono K
[Bone morphogenetic protein (BMP) receptors and signal transduction]
Nippon rinsho. Japanese journal of clinical medicine 1999;57(1):220-6.
1999: Kawabata M; Miyazono K
Signal transduction of the TGF-beta superfamily by Smad proteins.
Journal of biochemistry 1999;125(1):9-16.
1999: Yagi K; Goto D; Hamamoto T; Takenoshita S; Kato M; Miyazono K
Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3.
The Journal of biological chemistry 1999;274(2):703-9.
1999: Kawabata M; Imamura T; Inoue H; Hanai J; Nishihara A; Hanyu A; Takase M; Ishidou Y; Udagawa Y; Oeda E; Goto D; Yagi K; Kato M; Miyazono K
Intracellular signaling of the TGF-beta superfamily by Smad proteins.
Annals of the New York Academy of Sciences 1999;886():73-82.
1998: Saitoh M; ten Dijke P; Miyazono K; Ichijo H
Cloning and characterization of p70(S6K beta) defines a novel family of p70 S6 kinases.
Biochemical and biophysical research communications 1998;253(2):470-6.
1998: Li J; Tsuji K; Komori T; Miyazono K; Wrana J L; Ito Y; Nifuji A; Noda M
Smad2 overexpression enhances Smad4 gene expression and suppresses CBFA1 gene expression in osteoblastic osteosarcoma ROS17/2.8 cells and primary rat calvaria cells.
The Journal of biological chemistry 1998;273(47):31009-15.
1998: Nishihara A; Hanai J I; Okamoto N; Yanagisawa J; Kato S; Miyazono K; Kawabata M
Role of p300, a transcriptional coactivator, in signalling of TGF-beta.
Genes to cells : devoted to molecular & cellular mechanisms 1998;3(9):613-23.
1998: Nishitoh H; Saitoh M; Mochida Y; Takeda K; Nakano H; Rothe M; Miyazono K; Ichijo H
ASK1 is essential for JNK/SAPK activation by TRAF2.
Molecular cell 1998;2(3):389-95.
1998: Inoue H; Imamura T; Ishidou Y; Takase M; Udagawa Y; Oka Y; Tsuneizumi K; Tabata T; Miyazono K; Kawabata M
Interplay of signal mediators of decapentaplegic (Dpp): molecular characterization of mothers against dpp, Medea, and daughters against dpp.
Molecular biology of the cell 1998;9(8):2145-56.
1998: Goto D; Yagi K; Inoue H; Iwamoto I; Kawabata M; Miyazono K; Kato M
A single missense mutant of Smad3 inhibits activation of both Smad2 and Smad3, and has a dominant negative effect on TGF-beta signals.
FEBS letters 1998;430(3):201-4.
1998: Kawabata M; Inoue H; Hanyu A; Imamura T; Miyazono K
Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors.
The EMBO journal 1998;17(14):4056-65.
1998: Takeda K; Ichijo H; Fujii M; Mochida Y; Saitoh M; Nishitoh H; Sampath T K; Miyazono K
Identification of a novel bone morphogenetic protein-responsive gene that may function as a noncoding RNA.
The Journal of biological chemistry 1998;273(27):17079-85.
1998: Hori Y; Katoh T; Hirakata M; Joki N; Kaname S; Fukagawa M; Okuda T; Ohashi H; Fujita T; Miyazono K; Kurokawa K
Anti-latent TGF-beta binding protein-1 antibody or synthetic oligopeptides inhibit extracellular matrix expression induced by stretch in cultured rat mesangial cells.
Kidney international 1998;53(6):1616-25.
1998: Horie K; Yamashita H; Mogi A; Takenoshita S; Miyazono K
Lack of transforming growth factor-beta type II receptor expression in human retinoblastoma cells.
Journal of cellular physiology 1998;175(3):305-13.
1998: Saitoh M; Nishitoh H; Fujii M; Takeda K; Tobiume K; Sawada Y; Kawabata M; Miyazono K; Ichijo H
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.
The EMBO journal 1998;17(9):2596-606.
1998: Oeda E; Oka Y; Miyazono K; Kawabata M
Interaction of Drosophila inhibitors of apoptosis with thick veins, a type I serine/threonine kinase receptor for decapentaplegic.
The Journal of biological chemistry 1998;273(16):9353-6.
1998: Kawabata M; Imamura T; Miyazono K
Signal transduction by bone morphogenetic proteins.
Cytokine & growth factor reviews 1998;9(1):49-61.
1998: Takase M; Imamura T; Sampath T K; Takeda K; Ichijo H; Miyazono K; Kawabata M
Induction of Smad6 mRNA by bone morphogenetic proteins.
Biochemical and biophysical research communications 1998;244(1):26-9.
1998: Shimizu A; Kato M; Nakao A; Imamura T; ten Dijke P; Heldin C H; Kawabata M; Shimada S; Miyazono K
Identification of receptors and Smad proteins involved in activin signalling in a human epidermal keratinocyte cell line.
Genes to cells : devoted to molecular & cellular mechanisms 1998;3(2):125-34.
1997: Okochi H; Kato M; Nashiro K; Yoshie O; Miyazono K; Furue M
Expression of tetra-spans transmembrane family (CD9, CD37, CD53, CD63, CD81 and CD82) in normal and neoplastic human keratinocytes: an association of CD9 with alpha 3 beta 1 integrin.
The British journal of dermatology 1997;137(6):856-63.
1997: Yamashita H; Tobari I; Sawa M; Hori S; Miyazono K; Heldin C H; Heldin P; Dijke P T; Sampath T K; Suiryu T; Eguchi S; Kitano S; Suzuki S; Ichijo H; Kato M; Yamamoto T; Funazu E; Suzuki M; Ikegami Y; Kato S; Obata H; Horie K; Mogi Y; Seiya K; Sakai H
[Functions of the transforming growth factor-beta superfamily in eyes]
Nippon Ganka Gakkai zasshi 1997;101(12):927-47.
1997: Nakaoka T; Gonda K; Ogita T; Otawara-Hamamoto Y; Okabe F; Kira Y; Harii K; Miyazono K; Takuwa Y; Fujita T
Inhibition of rat vascular smooth muscle proliferation in vitro and in vivo by bone morphogenetic protein-2.
The Journal of clinical investigation 1997;100(11):2824-32.
1997: Tobiume K; Inage T; Takeda K; Enomoto S; Miyazono K; Ichijo H
Molecular cloning and characterization of the mouse apoptosis signal-regulating kinase 1.
Biochemical and biophysical research communications 1997;239(3):905-10.
1997: Imamura T; Takase M; Nishihara A; Oeda E; Hanai J; Kawabata M; Miyazono K
Smad6 inhibits signalling by the TGF-beta superfamily.
Nature 1997;389(6651):622-6.
1997: Nakao A; Imamura T; Souchelnytskyi S; Kawabata M; Ishisaki A; Oeda E; Tamaki K; Hanai J; Heldin C H; Miyazono K; ten Dijke P
TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4.
The EMBO journal 1997;16(17):5353-62.
1997: Yamashita H; Shimizu A; Kato M; Nishitoh H; Ichijo H; Hanyu A; Morita I; Kimura M; Makishima F; Miyazono K
Growth/differentiation factor-5 induces angiogenesis in vivo.
Experimental cell research 1997;235(1):218-26.
1997: Persson U; Souchelnytskyi S; Franzén P; Miyazono K; ten Dijke P; Heldin C H
Transforming growth factor (TGF-beta)-specific signaling by chimeric TGF-beta type II receptor with intracellular domain of activin type IIB receptor.
The Journal of biological chemistry 1997;272(34):21187-94.
1997: Miyazono K; Kawabata M
[TGF-beta signal transduction and Smad]
Seikagaku. The Journal of Japanese Biochemical Society 1997;69(6):424-8.
1997: Beppu H; Minowa O; Miyazono K; Kawabata M
cDNA cloning and genomic organization of the mouse BMP type II receptor.
Biochemical and biophysical research communications 1997;235(3):499-504.
1997: Olofsson A; Hellman U; Ten Dijke P; Grimsby S; Ichijo H; Morén A; Miyazono K; Heldin C H
Latent transforming growth factor-beta complex in Chinese hamster ovary cells contains the multifunctional cysteine-rich fibroblast growth factor receptor, also termed E-selectin-ligand or MG-160.
The Biochemical journal 1997;324 ( Pt 2)():427-34.
1997: Furue M; Kato M; Nakamura K; Nashiro K; Kikuchi K; Okochi H; Miyazono K; Tamaki K
Dysregulated expression of transforming growth factor beta and its type-I and type-II receptors in basal-cell carcinoma.
International journal of cancer. Journal international du cancer 1997;71(4):505-9.
1997: Miyazono K
TGF-beta receptors and signal transduction.
International journal of hematology 1997;65(2):97-104.
1997: Ichijo H; Nishida E; Irie K; ten Dijke P; Saitoh M; Moriguchi T; Takagi M; Matsumoto K; Miyazono K; Gotoh Y
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways.
Science (New York, N.Y.) 1997;275(5296):90-4.
1996: Yamashita H; Ten Dijke P; Heldin C H; Miyazono K
Bone morphogenetic protein receptors.
Bone 1996;19(6):569-74.
1996: Souchelnytskyi S; ten Dijke P; Miyazono K; Heldin C H
Phosphorylation of Ser165 in TGF-beta type I receptor modulates TGF-beta1-induced cellular responses.
The EMBO journal 1996;15(22):6231-40.
1996: Harumiya S; Takeda K; Sugiura T; Fukumoto Y; Tachikawa H; Miyazono K; Fujimoto D; Ichijo H
Characterization of ficolins as novel elastin-binding proteins and molecular cloning of human ficolin-1.
Journal of biochemistry 1996;120(4):745-51.
1996: Okadome T; Oeda E; Saitoh M; Ichijo H; Moses H L; Miyazono K; Kawabata M
Characterization of the interaction of FKBP12 with the transforming growth factor-beta type I receptor in vivo.
The Journal of biological chemistry 1996;271(36):21687-90.
1996: Nishitoh H; Ichijo H; Kimura M; Matsumoto T; Makishima F; Yamaguchi A; Yamashita H; Enomoto S; Miyazono K
Identification of type I and type II serine/threonine kinase receptors for growth/differentiation factor-5.
The Journal of biological chemistry 1996;271(35):21345-52.
1996: ten Dijke P; Miyazono K; Heldin C H
Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors.
Current opinion in cell biology 1996;8(2):139-45.
1996: Miyazono K
[Transforming growth factor-beta and its receptors]
Nippon yakurigaku zasshi. Folia pharmacologica Japonica 1996;107(3):133-40.
1996: Yamada N; Kato M; ten Dijke P; Yamashita H; Sampath T K; Heldin C H; Miyazono K; Funa K
Bone morphogenetic protein type IB receptor is progressively expressed in malignant glioma tumours.
British journal of cancer 1996;73(5):624-9.
1996: de Vries C J; de Boer J; Joore J; Strähle U; van Achterberg T A; Huylebroeck D; Verschueren K; Miyazono K; van den Eijnden-van Raaij A J; Zivkovic D
Active complex formation of type I and type II activin and TGF beta receptors in vivo as studied by overexpression in zebrafish embryos.
Mechanisms of development 1996;54(2):225-36.
1996: Saitoh M; Nishitoh H; Amagasa T; Miyazono K; Takagi M; Ichijo H
Identification of important regions in the cytoplasmic juxtamembrane domain of type I receptor that separate signaling pathways of transforming growth factor-beta.
The Journal of biological chemistry 1996;271(5):2769-75.
1995: Olofsson A; Ichijo H; Morén A; ten Dijke P; Miyazono K; Heldin C H
Efficient association of an amino-terminally extended form of human latent transforming growth factor-beta binding protein with the extracellular matrix.
The Journal of biological chemistry 1995;270(52):31294-7.
1995: Rosenzweig B L; Imamura T; Okadome T; Cox G N; Yamashita H; ten Dijke P; Heldin C H; Miyazono K
Cloning and characterization of a human type II receptor for bone morphogenetic proteins.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):7632-6.
1995: Iseki S; Osumi-Yamashita N; Miyazono K; Franzén P; Ichijo H; Ohtani H; Hayashi Y; Eto K
Localization of transforming growth factor-beta type I and type II receptors in mouse development.
Experimental cell research 1995;219(2):339-47.
1995: Yamada N; Kato M; Yamashita H; Nistér M; Miyazono K; Heldin C H; Funa K
Enhanced expression of transforming growth factor-beta and its type-I and type-II receptors in human glioblastoma.
International journal of cancer. Journal international du cancer 1995;62(4):386-92.
1995: Yamashita H; ten Dijke P; Huylebroeck D; Sampath T K; Andries M; Smith J C; Heldin C H; Miyazono K
Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects.
The Journal of cell biology 1995;130(1):217-26.
1995: Verschueren K; Dewulf N; Goumans M J; Lonnoy O; Feijen A; Grimsby S; Vandi Spiegle K; ten Dijke P; Morén A; Vanscheeuwijck P; Heldin C H; Miyazono K; Mummery C; Van Den Eijnden-Van Raaij J; Huylebroeck D
Expression of type I and type IB receptors for activin in midgestation mouse embryos suggests distinct functions in organogenesis.
Mechanisms of development 1995;52(1):109-23.
1995: Dewulf N; Verschueren K; Lonnoy O; Morén A; Grimsby S; Vande Spiegle K; Miyazono K; Huylebroeck D; Ten Dijke P
Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis.
Endocrinology 1995;136(6):2652-63.
1995: Kato M; Ishizaki A; Hellman U; Wernstedt C; Kyogoku M; Miyazono K; Heldin C H; Funa K
A human keratinocyte cell line produces two autocrine growth inhibitors, transforming growth factor-beta and insulin-like growth factor binding protein-6, in a calcium- and cell density-dependent manner.
The Journal of biological chemistry 1995;270(21):12373-9.
1995: Franzén P; Heldin C H; Miyazono K
The GS domain of the transforming growth factor-beta type I receptor is important in signal transduction.
Biochemical and biophysical research communications 1995;207(2):682-9.
1995: Yamashita H; Okadome T; Franzén P; ten Dijke P; Heldin C H; Miyazono K
A rat pituitary tumor cell line (GH3) expresses type I and type II receptors and other cell surface binding protein(s) for transforming growth factor-beta.
The Journal of biological chemistry 1995;270(2):770-4.
1995: Colosetti P; Olsson T; Miyazono K; Funa K
Axotomy of rat facial nerve induces TGF-beta and latent TGF-beta binding protein.
Brain research bulletin 1995;37(6):561-7.
1994: Okadome T; Yamashita H; Franzén P; Morén A; Heldin C H; Miyazono K
Distinct roles of the intracellular domains of transforming growth factor-beta type I and type II receptors in signal transduction.
The Journal of biological chemistry 1994;269(49):30753-6.
1994: Morén A; Olofsson A; Stenman G; Sahlin P; Kanzaki T; Claesson-Welsh L; ten Dijke P; Miyazono K; Heldin C H
Identification and characterization of LTBP-2, a novel latent transforming growth factor-beta-binding protein.
The Journal of biological chemistry 1994;269(51):32469-78.
1994: Miyazono K; ten Dijke P; Yamashita H; Heldin C H
Signal transduction via serine/threonine kinase receptors.
Seminars in cell biology 1994;5(6):389-98.
1994: Yamashita H; ten Dijke P; Franzén P; Miyazono K; Heldin C H
Formation of hetero-oligomeric complexes of type I and type II receptors for transforming growth factor-beta.
The Journal of biological chemistry 1994;269(31):20172-8.
1994: Usuki K; Gonez L J; Wernstedt C; Morén A; Miyazono K; Claesson-Welsh L; Heldin C H
Structural properties of 3.0 kb and 3.2 kb transcripts encoding platelet-derived endothelial cell growth factor/thymidine phosphorylase in A431 cells.
Biochimica et biophysica acta 1994;1222(3):411-4.
1994: ten Dijke P; Yamashita H; Sampath T K; Reddi A H; Estevez M; Riddle D L; Ichijo H; Heldin C H; Miyazono K
Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4.
The Journal of biological chemistry 1994;269(25):16985-8.
1994: Taketazu F; Kato M; Gobl A; Ichijo H; ten Dijke P; Itoh J; Kyogoku M; Rönnelid J; Miyazono K; Heldin C H
Enhanced expression of transforming growth factor-beta s and transforming growth factor-beta type II receptor in the synovial tissues of patients with rheumatoid arthritis.
Laboratory investigation; a journal of technical methods and pathology 1994;70(5):620-30.
1994: ten Dijke P; Yamashita H; Ichijo H; Franzén P; Laiho M; Miyazono K; Heldin C H
Characterization of type I receptors for transforming growth factor-beta and activin.
Science (New York, N.Y.) 1994;264(5155):101-4.
1994: Yamazaki M; Minota S; Sakurai H; Miyazono K; Yamada A; Kanazawa I; Kawai M
Expression of transforming growth factor-beta 1 and its relation to endomysial fibrosis in progressive muscular dystrophy.
The American journal of pathology 1994;144(2):221-6.
1994: Yamashita H; Ichijo H; Grimsby S; Morén A; ten Dijke P; Miyazono K
Endoglin forms a heteromeric complex with the signaling receptors for transforming growth factor-beta.
The Journal of biological chemistry 1994;269(3):1995-2001.
1994: Miyazono K; Ten Dijke P; Ichijo H; Heldin C H
Receptors for transforming growth factor-beta.
Advances in immunology 1994;55():181-220.
1994: Stenman G; Sahlin P; Olofsson A; Geurts van Kessel A; Miyazono K
Assignment of the gene encoding the latent TGF-beta 1-binding protein (LTBP1) to human chromosome 2, region p12-->q22.
Cytogenetics and cell genetics 1994;66(2):117-9.
1994: ten Dijke P; Franzén P; Yamashita H; Ichijo H; Heldin C H; Miyazono K
Serine/threonine kinase receptors.
Progress in growth factor research 1994;5(1):55-72.
1993: Franzén P; ten Dijke P; Ichijo H; Yamashita H; Schulz P; Heldin C H; Miyazono K
Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor.
Cell 1993;75(4):681-92.
1993: ten Dijke P; Ichijo H; Franzén P; Schulz P; Saras J; Toyoshima H; Heldin C H; Miyazono K
Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity.
Oncogene 1993;8(10):2879-87.
1993: Ichijo H; Yamashita H; ten Dijke P; Eto Y; Heldin C H; Miyazono K
Characterization of in vivo phosphorylation of activin type II receptor.
Biochemical and biophysical research communications 1993;194(3):1508-14.
1993: Waltenberger J; Wanders A; Fellström B; Miyazono K; Heldin C H; Funa K
Induction of transforming growth factor-beta during cardiac allograft rejection.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(2):1147-57.
1993: Franzén P; Ichijo H; Miyazono K
Different signals mediate transforming growth factor-beta 1-induced growth inhibition and extracellular matrix production in prostatic carcinoma cells.
Experimental cell research 1993;207(1):1-7.
1993: Ichijo H; Hellman U; Wernstedt C; Gonez L J; Claesson-Welsh L; Heldin C H; Miyazono K
Molecular cloning and characterization of ficolin, a multimeric protein with fibrinogen- and collagen-like domains.
The Journal of biological chemistry 1993;268(19):14505-13.
1993: Colosetti P; Hellman U; Heldin C H; Miyazono K
Ca2+ binding of latent transforming growth factor-beta 1 binding protein.
FEBS letters 1993;320(2):140-4.
1993: Miyazono K; Heldin C H
The mechanism of action of transforming growth factor-beta.
Gastroenterologia Japonica 1993;28 Suppl 4():81-5; discussion 86-7.
1993: Waltenberger J; Lundin L; Oberg K; Wilander E; Miyazono K; Heldin C H; Funa K
Involvement of transforming growth factor-beta in the formation of fibrotic lesions in carcinoid heart disease.
The American journal of pathology 1993;142(1):71-8.
1993: Miyazono K; Ichijo H; Heldin C H
Transforming growth factor-beta: latent forms, binding proteins and receptors.
Growth factors (Chur, Switzerland) 1993;8(1):11-22.
1992: Morén A; Ichijo H; Miyazono K
Molecular cloning and characterization of the human and porcine transforming growth factor-beta type III receptors.
Biochemical and biophysical research communications 1992;189(1):356-62.
1992: Olofsson A; Miyazono K; Kanzaki T; Colosetti P; Engström U; Heldin C H
Transforming growth factor-beta 1, -beta 2, and -beta 3 secreted by a human glioblastoma cell line. Identification of small and different forms of large latent complexes.
The Journal of biological chemistry 1992;267(27):19482-8.
1992: Hanazono Y; Miyazono K; Piao Y F; Taketazu F; Chiba S; Miyagawa K; Hirai H; Sakamoto S; Miura Y; Yazaki Y
Treatment of acute nonlymphocytic leukemia by combination of recombinant human granulocyte colony-stimulating factor and cytotoxic agents: a report of six cases.
International journal of hematology 1992;55(3):243-8.
1992: Usuki K; Saras J; Waltenberger J; Miyazono K; Pierce G; Thomason A; Heldin C H
Platelet-derived endothelial cell growth factor has thymidine phosphorylase activity.
Biochemical and biophysical research communications 1992;184(3):1311-6.
1992: Miyazono K; Thyberg J; Heldin C H
Retention of the transforming growth factor-beta 1 precursor in the Golgi complex in a latent endoglycosidase H-sensitive form.
The Journal of biological chemistry 1992;267(8):5668-75.
1992: Stenman G; Sahlin P; Dumanski J P; Hagiwara K; Ishikawa F; Miyazono K; Collins V P; Heldin C H
Regional localization of the human platelet-derived endothelial cell growth factor (ECGF1) gene to chromosome 22q13.
Cytogenetics and cell genetics 1992;59(1):22-3.
1992: Taketazu F; Miyagawa K; Ichijo H; Oshimi K; Mizoguchi H; Hirai H; Miyazono K; Takaku F
Decreased level of transforming growth factor-beta in blood lymphocytes of patients with aplastic anemia.
Growth factors (Chur, Switzerland) 1992;6(1):85-90.
1991: Hanazono Y; Miyazono K; Tsuchimochi H; Yamaoki K; Miyagawa K; Hirai H; Yazaki Y; Takaku F
Treatment of infective endocarditis with granulocyte colony-stimulating factor.
Japanese journal of medicine 1991;30(6):593-6.
1991: Heldin C H; Usuki K; Miyazono K
Platelet-derived endothelial cell growth factor.
Journal of cellular biochemistry 1991;47(3):208-10.
1991: Ichijo H; Rönnstrand L; Miyagawa K; Ohashi H; Heldin C H; Miyazono K
Purification of transforming growth factor-beta 1 binding proteins from porcine uterus membranes.
The Journal of biological chemistry 1991;266(33):22459-64.
1991: Usuki K; Miyazono K; Heldin C H
Covalent linkage between nucleotides and platelet-derived endothelial cell growth factor.
The Journal of biological chemistry 1991;266(30):20525-31.
1991: Miyazono K; Takaku F
Platelet-derived endothelial cell growth factor: structure and function.
Japanese circulation journal 1991;55(10):1022-6.
1991: Shibuya K; Chiba S; Miyagawa K; Kitamura T; Miyazono K; Takaku F
Structural and functional analyses of glycosylation on the distinct molecules of human GM-CSF receptors.
European journal of biochemistry / FEBS 1991;198(3):659-66.
1991: Miyazono K; Olofsson A; Colosetti P; Heldin C H
A role of the latent TGF-beta 1-binding protein in the assembly and secretion of TGF-beta 1.
The EMBO journal 1991;10(5):1091-101.
1991: Ishikawa F; Miyazono K
[Platelet-derived endothelial cell growth factor]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1991;36(7):1268-72.
1991: Miyazono K
[Structure and function of transforming growth factor-beta]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1991;36(7):1350-6.
1991: Hagiwara K; Stenman G; Honda H; Sahlin P; Andersson A; Miyazono K; Heldin C H; Ishikawa F; Takaku F
Organization and chromosomal localization of the human platelet-derived endothelial cell growth factor gene.
Molecular and cellular biology 1991;11(4):2125-32.
1991: Miyazono K; Usuki K
[Structure and function of platelet-derived endothelial cell growth factor]
Seikagaku. The Journal of Japanese Biochemical Society 1991;63(4):290-3.
1991: Taketazu F; Chiba S; Shibuya K; Kuwaki T; Tsumura H; Miyazono K; Miyagawa K; Takaku F
IL-3 specifically inhibits GM-CSF binding to the higher affinity receptor.
Journal of cellular physiology 1991;146(2):251-7.
1991: Miyazono K; Heldin C H
Latent forms of TGF-beta: molecular structure and mechanisms of activation.
Ciba Foundation symposium 1991;157():81-9; discussion 89-92.
1991: Miyazono K; Usuki K; Heldin C H
Platelet-derived endothelial cell growth factor.
Progress in growth factor research 1991;3(3):207-17.
1990: Chiba S; Shibuya K; Miyazono K; Tojo A; Oka Y; Miyagawa K; Takaku F
Affinity purification of human granulocyte macrophage colony-stimulating factor receptor alpha-chain. Demonstration of binding by photoaffinity labeling.
The Journal of biological chemistry 1990;265(32):19777-81.
1990: Hanazono Y; Hosoi T; Kuwaki T; Matsuki S; Miyazono K; Miyagawa K; Takaku F
Structural analysis of the receptors for granulocyte colony-stimulating factor on neutrophils.
Experimental hematology 1990;18(10):1097-103.
1990: Mitani K; Sato Y; Tojo A; Ishikawa F; Kobayashi Y; Miura Y; Miyazono K; Urabe A; Takaku F
Philadelphia chromosome positive B-cell type malignant lymphoma expressing an aberrant 190 kDa bcr-abl protein.
British journal of haematology 1990;76(2):221-5.
1990: Yuo A; Miyazono K; Urabe A; Takaku F
Characteristics of granulocyte-macrophage colony formation in chronic myelomonocytic leukemia: a comparative study with other myelodysplastic and myeloproliferative disorders.
Japanese journal of cancer research : Gann 1990;81(8):820-6.
1990: Usuki K; Norberg L; Larsson E; Miyazono K; Hellman U; Wernstedt C; Rubin K; Heldin C H
Localization of platelet-derived endothelial cell growth factor in human placenta and purification of an alternatively processed form.
Cell regulation 1990;1(8):577-84.
1990: Kanzaki T; Olofsson A; Morén A; Wernstedt C; Hellman U; Miyazono K; Claesson-Welsh L; Heldin C H
TGF-beta 1 binding protein: a component of the large latent complex of TGF-beta 1 with multiple repeat sequences.
Cell 1990;61(6):1051-61.
1990: Miyagawa K; Chiba S; Shibuya K; Piao Y F; Matsuki S; Yokota J; Terada M; Miyazono K; Takaku F
Frequent expression of receptors for granulocyte-macrophage colony-stimulating factor on human nonhematopoietic tumor cell lines.
Journal of cellular physiology 1990;143(3):483-7.
1990: Kuwaki T; Hosoi T; Hanazono Y; Tsumura H; Ishikawa F; Miyazono K; Miyagawa K; Takaku F
Distribution of human granulocyte colony-stimulating factor receptors on hematopoietic and nonhematopoietic tumor cell lines.
Japanese journal of cancer research : Gann 1990;81(6-7):560-3.
1990: Chiba S; Shibuya K; Piao Y F; Tojo A; Sasaki N; Matsuki S; Miyagawa K; Miyazono K; Takaku F
Identification and cellular distribution of distinct proteins forming human GM-CSF receptor.
Cell regulation 1990;1(4):327-35.
1990: Piao Y F; Ichijo H; Miyagawa K; Ohashi H; Takaku F; Miyazono K
Latent form of transforming growth factor-beta 1 acts as a potent growth inhibitor on a human erythroleukemia cell line.
Biochemical and biophysical research communications 1990;167(1):27-32.
1990: Chiba S; Tojo A; Kitamura T; Urabe A; Miyazono K; Takaku F
Characterization and molecular features of the cell surface receptor for human granulocyte-macrophage colony-stimulating factor.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1990;4(1):29-36.
1990: Miyazono K; Yuki K; Takaku F; Wernstedt C; Kanzaki T; Olofsson A; Hellman U; Heldin C H
Latent forms of TGF-beta: structure and biology.
Annals of the New York Academy of Sciences 1990;593():51-8.
1989: Miyazono K; Takaku F
Platelet-derived growth factors.
Blood reviews 1989;3(4):269-76.
1989: Yuo A; Kitagawa S; Ohsaka A; Ohta M; Miyazono K; Okabe T; Urabe A; Saito M; Takaku F
Recombinant human granulocyte colony-stimulating factor as an activator of human granulocytes: potentiation of responses triggered by receptor-mediated agonists and stimulation of C3bi receptor expression and adherence.
Blood 1989;74(6):2144-9.
1989: Usuki K; Heldin N E; Miyazono K; Ishikawa F; Takaku F; Westermark B; Heldin C H
Production of platelet-derived endothelial cell growth factor by normal and transformed human cells in culture.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(19):7427-31.
1989: Piao Y F; Chiba S; Tojo A; Urabe A; Nara N; Miyazono K; Takaku F
Binding properties and proliferative effects of human recombinant granulocyte-macrophage colony-stimulating factor in primary leukemia and lymphoma.
Japanese journal of cancer research : Gann 1989;80(9):887-94.
1989: Kitamura T; Tange T; Terasawa T; Chiba S; Kuwaki T; Miyagawa K; Piao Y F; Miyazono K; Urabe A; Takaku F
Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin.
Journal of cellular physiology 1989;140(2):323-34.
1989: Hino M; Tojo A; Miyazono K; Miura Y; Chiba S; Eto Y; Shibai H; Takaku F
Characterization of cellular receptors for erythroid differentiation factor on murine erythroleukemia cells.
The Journal of biological chemistry 1989;264(17):10309-14.
1989: Kuwaki T; Kitamura T; Tojo A; Matsuki S; Tamai Y; Miyazono K; Takaku F
Characterization of human interleukin-3 receptors on a multi-factor-dependent cell line.
Biochemical and biophysical research communications 1989;161(1):16-22.
1989: Ishikawa F; Miyazono K; Hellman U; Drexler H; Wernstedt C; Hagiwara K; Usuki K; Takaku F; Risau W; Heldin C H
Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor.
Nature 1989;338(6216):557-62.
1989: Miyazono K; Heldin C H
Role for carbohydrate structures in TGF-beta 1 latency.
Nature 1989;338(6211):158-60.
1989: Kitamura T; Tojo A; Kuwaki T; Chiba S; Miyazono K; Urabe A; Takaku F
Identification and analysis of human erythropoietin receptors on a factor-dependent cell line, TF-1.
Blood 1989;73(2):375-80.
1989: Kobayashi Y; Okabe T; Ozawa K; Chiba S; Hino M; Miyazono K; Urabe A; Takaku F
Treatment of myelodysplastic syndromes with recombinant human granulocyte colony-stimulating factor: a preliminary report.
The American journal of medicine 1989;86(2):178-82.
1989: Heldin C H; Miyazono K; Claesson-Welsh L; Westermark B
Growth regulatory proteins from human platelets.
Princess Takamatsu symposia 1989;20():81-92.
1988: Hino M; Tojo A; Miyazono K; Urabe A; Takaku F
Effects of type beta transforming growth factors on haematopoietic progenitor cells.
British journal of haematology 1988;70(2):143-7.
1988: Miyazono K; Hellman U; Wernstedt C; Heldin C H
Latent high molecular weight complex of transforming growth factor beta 1. Purification from human platelets and structural characterization.
The Journal of biological chemistry 1988;263(13):6407-15.

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