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Steven Mizel

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Kimberly M Clark; John B Johnson; Nancy D Kock; Steven B Mizel; Griffith D Parks
Parainfluenza virus 5-based vaccine vectors expressing vaccinia virus (VACV) antigens provide long-term protection in mice from lethal intranasal VACV challenge.
John T Bates; Aaron H Graff; James P Phipps; Jason M Grayson; Steven B Mizel
Enhanced antigen processing of flagellin fusion proteins promotes the antigen-specific CD8+ T cell response independently of TLR5 and MyD88.
Steven B Mizel; John T Bates
Flagellin as an adjuvant: cellular mechanisms and potential.

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All Publications

2011: Kimberly M Clark; John B Johnson; Nancy D Kock; Steven B Mizel; Griffith D Parks
Parainfluenza virus 5-based vaccine vectors expressing vaccinia virus (VACV) antigens provide long-term protection in mice from lethal intranasal VACV challenge.
Virology 2011;419(2):97-106.
2011: John T Bates; Aaron H Graff; James P Phipps; Jason M Grayson; Steven B Mizel
Enhanced antigen processing of flagellin fusion proteins promotes the antigen-specific CD8+ T cell response independently of TLR5 and MyD88.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(11):6255-62.
2010: Steven B Mizel; John T Bates
Flagellin as an adjuvant: cellular mechanisms and potential.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(10):5677-82.
2010: Maryam Ahmed; Shelby Puckett; Subhashini Arimilli; Cassandra L Braxton; Steven B Mizel; Douglas S Lyles
Stimulation of human dendritic cells by wild-type and M protein mutant vesicular stomatitis viruses engineered to express bacterial flagellin.
Journal of virology 2010;84(22):12093-8.
2010: Kristen N Delaney; James P Phipps; John B Johnson; Steven B Mizel
A recombinant flagellin-poxvirus fusion protein vaccine elicits complement-dependent protection against respiratory challenge with vaccinia virus in mice.
Viral immunology 2010;23(2):201-10.
2010: Cassandra L Braxton; Shelby H Puckett; Steven B Mizel; Douglas S Lyles
Protection against lethal vaccinia virus challenge by using an attenuated matrix protein mutant vesicular stomatitis virus vaccine vector expressing poxvirus antigens.
Journal of virology 2010;84(7):3552-61.
2009: Eric T Weimer; Sean E Ervin; Daniel J Wozniak; Steven B Mizel
Immunization of young African green monkeys with OprF epitope 8-OprI-type A- and B-flagellin fusion proteins promotes the production of protective antibodies against nonmucoid Pseudomonas aeruginosa.
Vaccine 2009;27(48):6762-9.
2009: John T Bates; Satoshi Uematsu; Shizuo Akira; Steven B Mizel
Direct stimulation of tlr5+/+ CD11c+ cells is necessary for the adjuvant activity of flagellin.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(12):7539-47.
2009: Eric T Weimer; Haiping Lu; Nancy D Kock; Daniel J Wozniak; Steven B Mizel
A fusion protein vaccine containing OprF epitope 8, OprI, and type A and B flagellins promotes enhanced clearance of nonmucoid Pseudomonas aeruginosa.
Infection and immunity 2009;77(6):2356-66.
2009: Steven B Mizel; Aaron H Graff; Nammalwar Sriranganathan; Sean Ervin; Cynthia J Lees; Mark Lively; Roy R Hantgan; Michael J Thomas; James Wood; Brian Bell
Flagellin-F1-V fusion protein is an effective plague vaccine in mice and two species of nonhuman primates.
Clinical and vaccine immunology : CVI 2009;16(1):21-8.
2008: Subhashini Arimilli; John B Johnson; Kimberly M Clark; Aaron H Graff; Martha Alexander-Miller; Steven B Mizel; Griffith D Parks
Engineered expression of the TLR5 ligand flagellin enhances paramyxovirus activation of human dendritic cell function.
Journal of virology 2008;82(22):10975-85.
2008: John T Bates; Anna N Honko; Aaron H Graff; Nancy D Kock; Steven B Mizel
Mucosal adjuvant activity of flagellin in aged mice.
Mechanisms of ageing and development 2008;129(5):271-81.
2006: Anna N Honko; Nammalwar Sriranganathan; Cynthia J Lees; Steven B Mizel
Flagellin is an effective adjuvant for immunization against lethal respiratory challenge with Yersinia pestis.
Infection and immunity 2006;74(2):1113-20.
2005: A Phillip West; Brooke A Dancho; Steven B Mizel
Gangliosides inhibit flagellin signaling in the absence of an effect on flagellin binding to toll-like receptor 5.
The Journal of biological chemistry 2005;280(10):9482-8.
2005: Anna N Honko; Steven B Mizel
Effects of flagellin on innate and adaptive immunity.
Immunologic research 2005;33(1):83-101.
2004: Anna N Honko; Steven B Mizel
Mucosal administration of flagellin induces innate immunity in the mouse lung.
Infection and immunity 2004;72(11):6676-9.
2003: Steven B Mizel; A Phillip West; Roy R Hantgan
Identification of a sequence in human toll-like receptor 5 required for the binding of Gram-negative flagellin.
The Journal of biological chemistry 2003;278(26):23624-9.
2003: Steven B Mizel; Anna N Honko; Marlena A Moors; Pameeka S Smith; A Phillip West
Induction of macrophage nitric oxide production by Gram-negative flagellin involves signaling via heteromeric Toll-like receptor 5/Toll-like receptor 4 complexes.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(12):6217-23.
2002: Steven B Mizel; James A Snipes
Gram-negative flagellin-induced self-tolerance is associated with a block in interleukin-1 receptor-associated kinase release from toll-like receptor 5.
The Journal of biological chemistry 2002;277(25):22414-20.
2001: Marlena A Moors; Liwu Li; Steven B Mizel
Activation of interleukin-1 receptor-associated kinase by gram-negative flagellin.
Infection and immunity 2001;69(7):4424-9.
2000: P F McDermott; F Ciacci-Woolwine; James A Snipes; Steven B Mizel
High-affinity interaction between gram-negative flagellin and a cell surface polypeptide results in human monocyte activation.
Infection and immunity 2000;68(10):5525-9.
2000: Marlena A Moors; Steven B Mizel
Proteasome-mediated regulation of interleukin-1beta turnover and export in human monocytes.
Journal of leukocyte biology 2000;68(1):131-6.
2000: C A Learn; Steven B Mizel; Charles E McCall
mRNA and protein stability regulate the differential expression of pro- and anti-inflammatory genes in endotoxin-tolerant THP-1 cells.
The Journal of biological chemistry 2000;275(16):12185-93.
1999: F Ciacci-Woolwine; P F McDermott; Steven B Mizel
Induction of cytokine synthesis by flagella from gram-negative bacteria may be dependent on the activation or differentiation state of human monocytes.
Infection and immunity 1999;67(10):5176-85.
1998: F Ciacci-Woolwine; Ian C Blomfield; S H Richardson; Steven B Mizel
Salmonella flagellin induces tumor necrosis factor alpha in a human promonocytic cell line.
Infection and immunity 1998;66(3):1127-34.
1997: F Ciacci-Woolwine; Louis S Kucera; S H Richardson; Nathan Iyer; Steven B Mizel
Salmonellae activate tumor necrosis factor alpha production in a human promonocytic cell line via a released polypeptide.
Infection and immunity 1997;65(11):4624-33.
1995: Steven B Mizel; Louis S Kucera; S H Richardson; F Ciacci; N P Iyer
Regulation of macrophage activation and human immunodeficiency virus production by invasive Salmonella strains.
Infection and immunity 1995;63(5):1820-6.