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Takuya Mizuno

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Saori Umeki; Yasuo Ema; Yorihiro Nishimura; Masaru Okuda; Masayuki Shimojima; Ryoichi Suzuki; Takuya Mizuno
Anti-adhesive property of P-selectin glycoprotein ligand-1 (PSGL-1) due to steric hindrance effect.
Saori Umeki; Jumpei Yamazaki; Yasuo Ema; Toshiharu Hayashi; Hiroko Hiraoka; Masahito Kubo; Yasuhiko Okamura; Masaru Okuda; Ryoichi Suzuki; Kenji Tani; Hajime Tsujimoto; Takuya Mizuno
Establishment of five canine lymphoma cell lines and tumor formation in a xenotransplantation model.
Nobuyuki Fujiwara; Hideyoshi Kawasaki; Takuya Mizuno; Koichi Sato; Michael P Vitek; Ryotaro Yabe; Dale J Christensen; Takashi Ohama
A potential therapeutic application of SET/I2PP2A inhibitor OP449 for canine T-cell lymphoma.

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All Publications

2013: Saori Umeki; Yasuo Ema; Yorihiro Nishimura; Masaru Okuda; Masayuki Shimojima; Ryoichi Suzuki; Takuya Mizuno
Anti-adhesive property of P-selectin glycoprotein ligand-1 (PSGL-1) due to steric hindrance effect.
Journal of cellular biochemistry 2013;114(6):1271-85.
2013: Saori Umeki; Jumpei Yamazaki; Yasuo Ema; Toshiharu Hayashi; Hiroko Hiraoka; Masahito Kubo; Yasuhiko Okamura; Masaru Okuda; Ryoichi Suzuki; Kenji Tani; Hajime Tsujimoto; Takuya Mizuno
Establishment of five canine lymphoma cell lines and tumor formation in a xenotransplantation model.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2013;75(4):467-74.
2013: Nobuyuki Fujiwara; Hideyoshi Kawasaki; Takuya Mizuno; Koichi Sato; Michael P Vitek; Ryotaro Yabe; Dale J Christensen; Takashi Ohama
A potential therapeutic application of SET/I2PP2A inhibitor OP449 for canine T-cell lymphoma.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2013;75(3):349-54.
2012: T Nakashima; Y Yamamoto; Toshiharu Hayashi; Takuya Mizuno
Administration of interferon (IFN)-α exacerbates reovirus type-2-triggered autoimmune insulitis in DBA/1J mice.
Scandinavian journal of immunology 2012;76(4):378-86.
2012: Yutaka Terada; Toshiharu Hayashi; Hiroyuki Iwata; Hassan Youssef Abdel Hamid Mahmoud; Takuya Mizuno; Masami Mochizuki; Masahiro Morimoto; Yumiko Nagao; Keita Noguchi; Masaru Okuda; Hiroshi Shimoda; Masayuki Shimojima; Yuto Shiozaki; Yoshikazu Tanaka; Ken Maeda
Feline infectious peritonitis virus with a large deletion in the 5'-terminal region of the spike gene retains its virulence for cats.
The Journal of general virology 2012;93(Pt 9):1930-4.
2012: Tomomi Nakashima; Toshiharu Hayashi; Takuya Mizuno
Reovirus type-2 infection in newborn DBA/1J mice reduces the development of late allergic asthma.
International journal of experimental pathology 2012;93(3):234-42.
2012: Kenji Baba; Hiroko Hiraoka; Kazuhito Itamoto; Kozue Kitagawa; Takuya Mizuno; Akiteru Amimoto; Hiroshi Sato; Masaru Okuda
Ehrlichia canis infection in two dogs that emigrated from endemic areas.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2012;74(6):775-8.
2012: Takumi Okawa; Yuko Wada; Kenji Baba; Hiroko Hiraoka; Kazuhito Itamoto; Takuya Mizuno; Masaru Okuda
Development of high-grade B-cell lymphoma concurrent with T-cell chronic lymphocytic leukemia in a dog.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2012;74(5):677-80.
2012: Toshiharu Hayashi; Natsumi Shimoyama; Takuya Mizuno
Destruction of salivary and lacrimal glands by Th1-polarized reaction in a model of secondary Sjögren's syndrome in lupus-prone female NZB × NZWF(1) mice.
Inflammation 2012;35(2):638-46.
2011: Takako Shimokawa Miyama; Saori Umeki; Masaru Okuda; Kumiko Sada; Kenji Baba; Yasuyuki Endo; Hiroko Hiraoka; Masaharu Hisasue; Hisashi Inokuma; Takuya Mizuno
Neutropenia associated with osteomyelitis due to Hepatozoon canis infection in a dog.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2011;73(10):1389-93.
2011: Saori Umeki; Ryoichi Suzuki; Masayuki Shimojima; Yasuo Ema; Takuma Yanase; Hiroyuki Iwata; Masaru Okuda; Takuya Mizuno
Characterization of monoclonal antibodies against canine P-selectin glycoprotein ligand-1 (PSGL-1).
Veterinary immunology and immunopathology 2011;142(1-2):119-25.
2011: Takumi Okawa; Takuma Yanase; Takako Shimokawa Miyama; Hiroko Hiraoka; Kenji Baba; Kenji Tani; Masaru Okuda; Takuya Mizuno
Prekallikrein deficiency in a dog.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2011;73(1):107-11.
2010: Takako Shimokawa Miyama; Kazuhito Itamoto; Chihiro Yoshioka; Koji Minami; Takumi Okawa; Yuka Fujisaki; Hiroko Hiraoka; Takuya Mizuno; Masaru Okuda
Evaluation of the hemodynamic impact of continuous renal replacement therapy in healthy dogs.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2010;72(4):493-7.
2010: Takako Shimokawa Miyama; Chihiro Yoshioka; Koji Minami; Takumi Okawa; Hiroko Hiraoka; Kazuhito Itamoto; Takuya Mizuno; Masaru Okuda
Nafamostat mesilate is not appropriate as an anticoagulant during continuous renal replacement therapy in dogs.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2010;72(3):363-7.
2009: Takuya Mizuno; Ryoichi Suzuki; Saori Umeki; Masaru Okuda
Crossreactivity of antibodies to canine CD25 and Foxp3 and identification of canine CD4+CD25 +Foxp3+ cells in canine peripheral blood.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2009;71(12):1561-8.
2009: Takako Shimokawa Miyama; Emiko Iwamoto; Saori Umeki; Munekazu Nakaichi; Masaru Okuda; Takuya Mizuno
Magnetic resonance imaging and clinical findings in a miniature Schnauzer with hypodipsic hypernatremia.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2009;71(10):1387-91.
2009: Takuya Mizuno; Satoshi Kanbayashi; Takumi Okawa; Sadatoshi Maeda; Masaru Okuda
Molecular cloning of canine interleukin-31 and its expression in various tissues.
Veterinary immunology and immunopathology 2009;131(1-2):140-3.
2009: Emiko Iwamoto; Yuko Wada; Yuka Fujisaki; Saori Umeki; Miyuki Y Jones; Takuya Mizuno; Kazuhito Itamoto; Ken Maeda; Hiroyuki Iwata; Masaru Okuda
Nationwide survey of leptospira antibodies in dogs in Japan: results from microscopic agglutination test and enzyme-linked immunosorbent assay.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2009;71(9):1191-9.
2009: Hiroko Hiraoka; Koji Minami; Naoki Kaneko; Takako Shimokawa Miyama; Yasuhiko Okamura; Takuya Mizuno; Masaru Okuda
Aberrations of the FHIT gene and Fhit protein in canine lymphoma cell lines.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2009;71(6):769-77.
2009: Hiroko Hiraoka; Koji Minami; Naoki Kaneko; Takako Shimokawa Miyama; Takuya Mizuno; Masaru Okuda
Molecular cloning of the canine fragile histidine triad (FHIT) gene and Fhit protein expression in canine peripheral blood mononuclear cells.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2009;71(5):645-9.
2009: Naoki Kaneko; Yoshifumi Yamamoto; Yuko Wada; Takako Shimokawa Miyama; Hiroko Hiraoka; Kazuhito Itamoto; Takuya Mizuno; Munekazu Nakaichi; Tomoko Takahashi; Toshihiro Watari; Masaru Okuda
Application of polymerase chain reaction to analysis of antigen receptor rearrangements to support endoscopic diagnosis of canine alimentary lymphoma.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2009;71(5):555-9.
2009: Naoki Kaneko; Takashi Tanimoto; Masahiro Morimoto; Toshiharu Hayashi; Takako Shimokawa Miyama; Hiroko Hiraoka; Kazuhito Itamoto; Satoshi Une; Takuya Mizuno; Masaru Okuda
Use of formalin-fixed paraffin-embedded tissue and single-strand conformation polymorphism analysis for polymerase chain reaction of antigen receptor rearrangements in dogs.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2009;71(4):535-8.
2007: Hiroko Hiraoka; Masaharu Hisasue; Naho Nagashima; Takako Miyama; Takashi Tanimoto; Malaika Watanabe; Kazuhito Itamoto; Takuya Mizuno; Hisashi Inokuma; Masaru Okuda
A dog with myelodysplastic syndrome: chronic myelomonocytic leukemia.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2007;69(6):665-8.
2006: Takuya Mizuno; Kenji Baba; Yuko Goto; Kenichi Masuda; Koichi Ohno; Hajime Tsujimoto
Genomic cloning of feline Fas ligand gene and characterization of the transcription regulatory region.
Veterinary immunology and immunopathology 2006;114(3-4):305-12.
2006: Malaika Watanabe; Tatsuo Oikawa; Hiroko Hiraoka; Naoki Kaneko; Kazuhito Itamoto; Takuya Mizuno; Masaru Okuda; Hisashi Inokuma
Experimental inoculation of beagle dogs with Ehrlichia species detected from Ixodes ovatus.
Veterinary parasitology 2006;136(2):147-54.
2006: Tatsuo Oikawa; Masaru Okuda; Naoki Kaneko; Malaika Watanabe; Hiroko Hiraoka; Kazuhito Itamoto; Munekazu Nakaichi; Takuya Mizuno; Hisashi Inokuma
Cloning of the feline GADD45 cDNA and analysis of its mutation in feline lymphoma cell lines.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2006;68(3):297-301.
2004: Yasuhito Fujino; Zhiyong Ma; Hitoshi Satoh; Takuya Mizuno; Masaharu Hisasue; Kenji Baba; Kenichi Masuda; Koichi Ohno; Takafumi Onishi; Hajime Tsujimoto
Characterization of a newly established nonproducer lymphoma cell line for feline leukemia virus.
Veterinary immunology and immunopathology 2004;102(4):429-39.
2004: Takuya Mizuno; Kenji Baba; Yuko Goto; Kenichi Masuda; Koichi Ohno; Hajime Tsujimoto
Alternatively spliced transcripts of Fas mRNAs in feline lymphoid cells.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 2004;31(4):159-66.
2003: Takuya Mizuno; Yuko Goto; Kenji Baba; Yasuyuki Momoi; Yasuyuki Endo; Yorihiro Nishimura; Kenichi Masuda; Koichi Ohno; Hajime Tsujimoto
Quantitative analysis of Fas and Fas ligand mRNAs in a feline T-lymphoid cell line after infection with feline immunodeficiency virus and primary peripheral blood mononuclear cells obtained from cats infected with the virus.
Veterinary immunology and immunopathology 2003;93(3-4):117-23.
2003: Takuya Mizuno; Yuko Goto; Kenji Baba; Kenichi Masuda; Koichi Ohno; Hajime Tsujimoto
Molecular cloning of feline tumour necrosis factor receptor type I (TNFR I) and expression of TNFR I and TNFR II in lymphoid cells in cats.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 2003;30(2):107-13.
2002: Yuko Goto; Yoshiaki Nishimura; Kenji Baba; Takuya Mizuno; Yasuyuki Endo; Kenichi Masuda; Koichi Ohno; Hajime Tsujimoto
Association of plasma viral RNA load with prognosis in cats naturally infected with feline immunodeficiency virus.
Journal of virology 2002;76(19):10079-83.
2002: Akiko Kubota; Rui Kano; Takuya Mizuno; Masaharu Hisasue; Peter F Moore; Toshihiro Watari; Hajime Tsujimoto; Atsuhiko Hasegawa
Parathyroid hormone-related protein (PTHrP) produced by dog lymphoma cells.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2002;64(9):835-7.
2001: Shin Maeda; Takuya Mizuno; Kohei Yamashita; Keigo Kurata; Kenichi Masuda; Koichi Ohno; Hajime Tsujimoto
Molecular cloning of canine thymus and activation-regulated chemokine (TARC) gene and its expression in various tissues.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2001;63(9):1035-8.
2001: Masaharu Hisasue; H Okayama; Taro Okayama; T Suzuki; Takuya Mizuno; Yasuhito Fujino; K Naganobu; Atsuhiko Hasegawa; Toshihiro Watari; N Matsuki; Kenichi Masuda; Koichi Ohno; Hajime Tsujimoto
Hematologic abnormalities and outcome of 16 cats with myelodysplastic syndromes.
Journal of veterinary internal medicine / American College of Veterinary Internal Medicine 2001;15(5):471-7.
2001: Takuya Mizuno; Yuko Goto; Kenji Baba; Kenichi Masuda; Koichi Ohno; Hajime Tsujimoto
TNF-alpha-induced cell death in feline immunodeficiency virus-infected cells is mediated by the caspase cascade.
Virology 2001;287(2):446-55.
2000: Yuko Goto; Yorihiro Nishimura; Takuya Mizuno; Yasuyuki Endo; Kenji Baba; Yasuyuki Momoi; Toshihiro Watari; Atsuhiko Hasegawa; Hajime Tsujimoto
Quantification of viral ribonucleic acid in plasma of cats naturally infected with feline immunodeficiency virus.
American journal of veterinary research 2000;61(12):1609-13.
2000: Masaharu Hisasue; Kazuo Nishigaki; H Katae; K Yuri; Takuya Mizuno; Yasuhito Fujino; Asuka Setoguchi; Atsuhiko Hasegawa; Toshihiro Watari; Kenichi Masuda; Koichi Ohno; Hajime Tsujimoto
Clonality analysis of various hematopoietic disorders in cats naturally infected with feline leukemia virus.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2000;62(10):1059-65.
2000: Yasuyuki Endo; Yuko Goto; Yorihiro Nishimura; Takuya Mizuno; Toshihiro Watari; Atsuhiko Hasegawa; T Hohdatsu; Hidekazu Koyama; Hajime Tsujimoto
Inhibitory effect of stromal cell derived factor-1 on the replication of divergent strains of feline immunodeficiency virus in a feline T-lymphoid cell line.
Veterinary immunology and immunopathology 2000;74(3-4):303-14.
1999: Yorihiro Nishimura; Yuko Goto; K Yoneda; Yasuyuki Endo; Takuya Mizuno; M Hamachi; H Maruyama; H Kinoshita; S Koga; M Komori; Seigo Fushuku; K Ushinohama; Masao Akuzawa; Toshihiro Watari; Atsuhiko Hasegawa; Hajime Tsujimoto
Interspecies transmission of feline immunodeficiency virus from the domestic cat to the Tsushima cat (Felis bengalensis euptilura) in the wild.
Journal of virology 1999;73(9):7916-21.
1998: E Mortola; Yasuyuki Endo; Takuya Mizuno; Koichi Ohno; Toshihiro Watari; Hajime Tsujimoto; Atsuhiko Hasegawa
Effect of interleukin-12 and interleukin-10 on the virus replication and apoptosis in T-cells infected with feline immunodeficiency virus.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 1998;60(11):1181-5.
1998: Takuya Mizuno; Yasuyuki Endo; Yasuyuki Momoi; Yuko Goto; Yorihiro Nishimura; K Tsubota; Takeshi Mikami; Koichi Ohno; Toshihiro Watari; Hajime Tsujimoto; Atsuhiko Hasegawa
Molecular cloning of feline Fas antigen and Fas ligand cDNAs.
Veterinary immunology and immunopathology 1998;65(2-4):161-72.
1998: Yasuyuki Endo; Takuya Mizuno; Yorihiro Nishimura; Yuko Goto; Toshihiro Watari; Hajime Tsujimoto; Atsuhiko Hasegawa
Molecular cloning of feline CC-chemokine cDNAs.
Veterinary immunology and immunopathology 1998;65(2-4):113-23.
1998: Yorihiro Nishimura; Yuko Goto; H Pang; Yasuyuki Endo; Takuya Mizuno; Yasuyuki Momoi; Toshihiro Watari; Hajime Tsujimoto; Atsuhiko Hasegawa
Genetic heterogeneity of env gene of feline immunodeficiency virus obtained from multiple districts in Japan.
Virus research 1998;57(1):101-12.
1998: Yasuyuki Endo; K W Cho; Kazuo Nishigaki; Yasuyuki Momoi; Yorihiro Nishimura; Takuya Mizuno; Yuko Goto; Toshihiro Watari; Hajime Tsujimoto; Atsuhiko Hasegawa
Clinicopathological and immunological characteristics of six cats with granular lymphocyte tumors.
Comparative immunology, microbiology and infectious diseases 1998;21(1):27-42.
1997: Takuya Mizuno; Yasuyuki Momoi; Yasuyuki Endo; Yorihiro Nishimura; Yuko Goto; Koichi Ohno; Toshihiro Watari; Hajime Tsujimoto; Atsuhiko Hasegawa
Apoptosis enhanced by soluble factor produced in feline immunodeficiency virus infection.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 1997;59(11):1049-51.
1997: Yasuyuki Endo; K W Cho; Kazuo Nishigaki; Yasuyuki Momoi; Yorihiro Nishimura; Takuya Mizuno; Yuko Goto; Toshihiro Watari; Hajime Tsujimoto; Atsuhiko Hasegawa
Molecular characteristics of malignant lymphomas in cats naturally infected with feline immunodeficiency virus.
Veterinary immunology and immunopathology 1997;57(3-4):153-67.
1996: Yorihiro Nishimura; Shin-ichiro Nakamura; N Goto; T Hasegawa; H Pang; Yuko Goto; Hiroki Kato; HY Youn; Y Endo; Takuya Mizuno; Yasuyuki Momoi; Koichi Ohno; Toshihiro Watari; Hajime Tsujimoto; A Hasegawa
Molecular characterization of feline immunodeficiency virus genome obtained directly from organs of a naturally infected cat with marked neurological symptoms and encephalitis.
Archives of virology 1996;141(10):1933-48.
1996: Yasuyuki Momoi; Takuya Mizuno; Yorihiro Nishimura; Y Endo; Koichi Ohno; Toshihiro Watari; Ryo Goitsuka; Hajime Tsujimoto; A Hasegawa
Detection of apoptosis induced in peripheral blood lymphocytes from cats infected with feline immunodeficiency virus.
Archives of virology 1996;141(9):1651-9.