Yoshikuni Mizuno

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Asakawa Shuichi; Hattori Nobutaka; Shimizu Atsushi; Shimizu Yoshiko; Minoshima Shinsei; Mizuno Yoshikuni; Shimizu Nobuyoshi
Analysis of eighteen deletion breakpoints in the parkin gene.
Antonini Angelo; Tolosa Eduardo; Mizuno Yoshikuni; Yamamoto Mitsutoshi; Poewe Werner H
A reassessment of risks and benefits of dopamine agonists in Parkinson's disease.
Nishioka Kenya; Ross Owen A; Ishii Kenji; Kachergus Jennifer M; Ishiwata Kiichi; Kitagawa Mayumi; Kono Satoshi; Obi Tomokazu; Mizoguchi Koichi; Inoue Yuichi; Imai Hisamasa; Takanashi Masashi; Mizuno Yoshikuni; Farrer Matthew J; Hattori Nobutaka
Expanding the clinical phenotype of SNCA duplication carriers.

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2009: Asakawa Shuichi; Hattori Nobutaka; Shimizu Atsushi; Shimizu Yoshiko; Minoshima Shinsei; Mizuno Yoshikuni; Shimizu Nobuyoshi
Analysis of eighteen deletion breakpoints in the parkin gene.
Biochemical and biophysical research communications 2009;389(1):181-6.
2009: Antonini Angelo; Tolosa Eduardo; Mizuno Yoshikuni; Yamamoto Mitsutoshi; Poewe Werner H
A reassessment of risks and benefits of dopamine agonists in Parkinson's disease.
Lancet neurology 2009;8(10):929-37.
2009: Nishioka Kenya; Ross Owen A; Ishii Kenji; Kachergus Jennifer M; Ishiwata Kiichi; Kitagawa Mayumi; Kono Satoshi; Obi Tomokazu; Mizoguchi Koichi; Inoue Yuichi; Imai Hisamasa; Takanashi Masashi; Mizuno Yoshikuni; Farrer Matthew J; Hattori Nobutaka
Expanding the clinical phenotype of SNCA duplication carriers.
Movement disorders : official journal of the Movement Disorder Society 2009;24(12):1811-9.
2009: Sasaki Kumi; Shimura Hideki; Itaya Masako; Tanaka Ryota; Mori Hideo; Mizuno Yoshikuni; Kosik Kenneth S; Tanaka Shigeki; Hattori Nobutaka
Excitatory amino acid transporter 2 associates with phosphorylated tau and is localized in neurofibrillary tangles of tauopathic brains.
FEBS letters 2009;583(13):2194-200.
2009: Shiba Kahori; Arai Takeo; Sato Shigeto; Kubo Shin-ichiro; Ohba Yusuke; Mizuno Yoshikuni; Hattori Nobutaka
Parkin stabilizes PINK1 through direct interaction.
Biochemical and biophysical research communications 2009;383(3):331-5.
2009: Tomiyama Hiroyuki; Li Yuanzhe; Yoshino Hiroyo; Mizuno Yoshikuni; Kubo Shin-Ichiro; Toda Tatsushi; Hattori Nobutaka
Mutation analysis for DJ-1 in sporadic and familial parkinsonism: screening strategy in parkinsonism.
Neuroscience letters 2009;455(3):159-61.
2009: Oyama Genko; Hayashi Akito; Mizuno Yoshikuni; Hattori Nobutaka
Mechanism and treatment of dropped head syndrome associated with parkinsonism.
Parkinsonism & related disorders 2009;15(3):181-6.
2009: Fukae Jiro; Sato Shigeto; Shiba Kahori; Sato Ken-ichi; Mori Hideo; Sharp Philip A; Mizuno Yoshikuni; Hattori Nobutaka
Programmed cell death-2 isoform1 is ubiquitinated by parkin and increased in the substantia nigra of patients with autosomal recessive Parkinson's disease.
FEBS letters 2009;583(3):521-5.
2009: Yasuda Toru; Nihira Tomoko; Ren Yong-Ri; Cao Xu-Qing; Wada Keiichiro; Setsuie Rieko; Kabuta Tomohiro; Wada Keiji; Hattori Nobutaka; Mizuno Yoshikuni; Mochizuki Hideki
Effects of UCH-L1 on alpha-synuclein over-expression mouse model of Parkinson's disease.
Journal of neurochemistry 2009;108(4):932-44.
2009: Momma Kazunari; Funayama Manabu; Li Yuanzhe; Ichinose Hiroshi; Motoyoshi Kazuo; Hattori Nobutaka; Mizuno Yoshikuni; Kamakura Keiko
A new mutation in the GCH1 gene presents as early-onset Parkinsonism.
Parkinsonism & related disorders 2009;15(2):160-1.
2009: Ichikawa Naoki; Iwabuchi Kazuhisa; Kurihara Hidetake; Ishii Kumiko; Kobayashi Toshihide; Sasaki Takako; Hattori Nobutaka; Mizuno Yoshikuni; Hozumi Kentaro; Yamada Yoshihiko; Arikawa-Hirasawa Eri
Binding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowth.
Journal of cell science 2009;122(Pt 2):289-99.
2008: Tomiyama Hiroyuki; Kokubo Yasumasa; Sasaki Ryogen; Li Yuanzhe; Imamichi Yoko; Funayama Manabu; Mizuno Yoshikuni; Hattori Nobutaka; Kuzuhara Shigeki
Mutation analyses in amyotrophic lateral sclerosis/parkinsonism-dementia complex of the Kii peninsula, Japan.
Movement disorders : official journal of the Movement Disorder Society 2008;23(16):2344-8.
2008: Funayama Manabu; Li Yuanzhe; Tsoi Tak-Hong; Lam Ching-Wan; Ohi Takekazu; Yazawa Shogo; Uyama Eiichiro; Djaldetti Ruth; Melamed Eldad; Yoshino Hiroyo; Imamichi Yoko; Takashima Hiroshi; Nishioka Kenya; Sato Kenichi; Tomiyama Hiroyuki; Kubo Shin-Ichiro; Mizuno Yoshikuni; Hattori Nobutaka
Familial Parkinsonism with digenic parkin and PINK1 mutations.
Movement disorders : official journal of the Movement Disorder Society 2008;23(10):1461-5.
2008: Kumazawa Ryuya; Tomiyama Hiroyuki; Li Yuanzhe; Imamichi Yoko; Funayama Manabu; Yoshino Hiroyo; Yokochi Fusako; Fukusako Toshihiro; Takehisa Yasushi; Kashihara Kenichi; Kondo Tomoyoshi; Elibol Bulent; Bostantjopoulou Sevasti; Toda Tatsushi; Takahashi Hirohide; Yoshii Fumihito; Mizuno Yoshikuni; Hattori Nobutaka
Mutation analysis of the PINK1 gene in 391 patients with Parkinson disease.
Archives of neurology 2008;65(6):802-8.
2008: Mizuno Yoshikuni; Hattori Nobutaka; Kubo Shin-Ichiro; Sato Shigeto; Nishioka Kenya; Hatano Taku; Tomiyama Hiroyuki; Funayama Manabu; Machida Yutaka; Mochizuki Hideki
Progress in the pathogenesis and genetics of Parkinson's disease.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2008;363(1500):2215-27.
2008: Yamashiro Kazuo; Komine-Kobayashi Miki; Hatano Taku; Urabe Takao; Mochizuki Hideki; Hattori Nobutaka; Iwama Yoshitaka; Daida Hiroyuki; Sakai Michi; Nakayama Takeo; Mizuno Yoshikuni
The frequency of cardiac valvular regurgitation in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2008;23(7):935-41.
2008: Ning Y P; Kanai K; Tomiyama H; Li Y; Funayama M; Yoshino H; Sato S; Asahina M; Kuwabara S; Takeda A; Hattori T; Mizuno Y; Hattori N
PARK9-linked parkinsonism in eastern Asia: mutation detection in ATP13A2 and clinical phenotype.
Neurology 2008;70(16 Pt 2):1491-3.
2008: Obi Kimiko; Akiyama Haruhiko; Kondo Hiromi; Shimomura Yoko; Hasegawa Masato; Iwatsubo Takeshi; Mizuno Yoshikuni; Mochizuki Hideki
Relationship of phosphorylated alpha-synuclein and tau accumulation to Abeta deposition in the cerebral cortex of dementia with Lewy bodies.
Experimental neurology 2008;210(2):409-20.
2008: Obi T; Nishioka K; Ross O A; Terada T; Yamazaki K; Sugiura A; Takanashi M; Mizoguchi K; Mori H; Mizuno Y; Hattori N
Clinicopathologic study of a SNCA gene duplication patient with Parkinson disease and dementia.
Neurology 2008;70(3):238-41.
2008: Oizumi Hideki; Hayashita-Kinoh Hiromi; Hayakawa Hideki; Arai Hiroyuki; Furuya Tsuyoshi; Ren Yong-Ri; Yasuda Toru; Seki Tatsunori; Mizuno Yoshikuni; Mochizuki Hideki
Alteration in the differentiation-related molecular expression in the subventricular zone in a mouse model of Parkinson's disease.
Neuroscience research 2008;60(1):15-21.
2008: Tomiyama Hiroyuki; Mizuta Ikuko; Li Yuanzhe; Funayama Manabu; Yoshino Hiroyo; Li Lin; Murata Miho; Yamamoto Mitsutoshi; Kubo Shin-Ichiro; Mizuno Yoshikuni; Toda Tatsushi; Hattori Nobutaka
LRRK2 P755L variant in sporadic Parkinson's disease.
Journal of human genetics 2008;53(11-12):1012-5.
2007: Dubois Bruno; Burn David; Goetz Christopher; Aarsland Dag; Brown Richard G; Broe Gerald A; Dickson Dennis; Duyckaerts Charles; Cummings Jefferey; Gauthier Serge; Korczyn Amos; Lees Andrew; Levy Richard; Litvan Irene; Mizuno Yoshikuni; McKeith Ian G; Olanow C Warren; Poewe Werner; Sampaio Cristina; Tolosa Eduardo; Emre Murat
Diagnostic procedures for Parkinson's disease dementia: recommendations from the movement disorder society task force.
Movement disorders : official journal of the Movement Disorder Society 2007;22(16):2314-24.
2007: Mizuno Yoshikuni
[Discovery of the parkin gene; the gene for young onset autosomal recessive parkinsonism (AR)]
Rinsho shinkeigaku = Clinical neurology 2007;47(11):752-6.
2007: Mizuno Yoshikuni; Abe Takashi; Hasegawa Kazuko; Kuno Sadako; Kondo Tomoyoshi; Yamamoto Mitsutoshi; Nakashima Mitsuyoshi; Kanazawa Ichiro;
Ropinirole is effective on motor function when used as an adjunct to levodopa in Parkinson's disease: STRONG study.
Movement disorders : official journal of the Movement Disorder Society 2007;22(13):1860-5.
2007: Emre Murat; Aarsland Dag; Brown Richard; Burn David J; Duyckaerts Charles; Mizuno Yoshikino; Broe Gerald Anthony; Cummings Jeffrey; Dickson Dennis W; Gauthier Serge; Goldman Jennifer; Goetz Christopher; Korczyn Amos; Lees Andrew; Levy Richard; Litvan Irene; McKeith Ian; Olanow Warren; Poewe Werner; Quinn Niall; Sampaio Christina; Tolosa Eduardo; Dubois Bruno
Clinical diagnostic criteria for dementia associated with Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2007;22(12):1689-707; quiz 1837.
2007: Yasuda Toru; Fukuda-Tani Momo; Nihira Tomoko; Wada Keiichiro; Hattori Nobutaka; Mizuno Yoshikuni; Mochizuki Hideki
Correlation between levels of pigment epithelium-derived factor and vascular endothelial growth factor in the striatum of patients with Parkinson's disease.
Experimental neurology 2007;206(2):308-17.
2007: Takata Yukiko; Noda Kazuyuki; Fujishima Kenji; Hattori Nobutaka; Mizuno Yoshikuni; Okuma Yasuyuki
[A case of neuralgic amyotrophy in the lower extremity (lumbosacral radiculoplexus neuropathy)]
Brain and nerve = Shinkei kenkyu no shinpo 2007;59(4):435-8.
2007: Hara Kenju; Momose Yoshio; Tokiguchi Susumu; Shimohata Mitsuteru; Terajima Kenshi; Onodera Osamu; Kakita Akiyoshi; Yamada Mitsunori; Takahashi Hitoshi; Hirasawa Motoyuki; Mizuno Yoshikuni; Ogata Katsuhisa; Goto Jun; Kanazawa Ichiro; Nishizawa Masatoyo; Tsuji Shoji
Multiplex families with multiple system atrophy.
Archives of neurology 2007;64(4):545-51.
2007: Hatano Taku; Kubo Shin-Ichiro; Imai Satoshi; Maeda Masahiro; Ishikawa Kiyoshi; Mizuno Yoshikuni; Hattori Nobutaka
Leucine-rich repeat kinase 2 associates with lipid rafts.
Human molecular genetics 2007;16(6):678-90.
2007: Hayakawa Hideki; Hayashita-Kinoh Hiromi; Nihira Tomoko; Seki Tatsunori; Mizuno Yoshikuni; Mochizuki Hideki
The isolation of neural stem cells from the olfactory bulb of Parkinson's disease model.
Neuroscience research 2007;57(3):393-8.
2007: Funayama Manabu; Li Yuanzhe; Tomiyama Hiroyuki; Yoshino Hiroyo; Imamichi Yoko; Yamamoto Mitsutoshi; Murata Miho; Toda Tatsushi; Mizuno Yoshikuni; Hattori Nobutaka
Leucine-rich repeat kinase 2 G2385R variant is a risk factor for Parkinson disease in Asian population.
Neuroreport 2007;18(3):273-5.
2007: Fukae Jiro; Mizuno Yoshikuni; Hattori Nobutaka
Mitochondrial dysfunction in Parkinson's disease.
Mitochondrion 2007;7(1-2):58-62.
2007: Mogi Makio; Kondo Tomoyoshi; Mizuno Yoshikuni; Nagatsu Toshiharu
p53 protein, interferon-gamma, and NF-kappaB levels are elevated in the parkinsonian brain.
Neuroscience letters 2007;414(1):94-7.
2007: Arai Takeo; Fujishima Kenji; Kobayashi Hirokazu; Yamamoto Takuji; Mori Kentaro; Maeda Minoru; Mizuno Yoshikuni; Okuma Yasuyuki
Pseudoathetosis caused by migrated cervical disc.
Parkinsonism & related disorders 2007;13(1):59-61.
2007: Kono Satoshi; Shirakawa Kentaro; Ouchi Yasuomi; Sakamoto Masanobu; Ida Hiroyuki; Sugiura Takeshi; Tomiyama Hiroyuki; Suzuki Hitoshi; Takahashi Yoshitomo; Miyajima Hiroaki; Hattori Nobutaka; Mizuno Yoshikuni
Dopaminergic neuronal dysfunction associated with parkinsonism in both a Gaucher disease patient and a carrier.
Journal of the neurological sciences 2007;252(2):181-4.
2007: Yasuda T; Miyachi S; Kitagawa R; Wada K; Nihira T; Ren Y-R; Hirai Y; Ageyama N; Terao K; Shimada T; Takada M; Mizuno Y; Mochizuki H
Neuronal specificity of alpha-synuclein toxicity and effect of Parkin co-expression in primates.
Neuroscience 2007;144(2):743-53.
2007: Mizuno Yoshikuni; Kanazawa Ichiro; Kuno Sadako; Yanagisawa Nobuo; Yamamoto Mitsutoshi; Kondo Tomoyoshi
Placebo-controlled, double-blind dose-finding study of entacapone in fluctuating parkinsonian patients.
Movement disorders : official journal of the Movement Disorder Society 2007;22(1):75-80.
2007: Setsuie Rieko; Wang Yu-Lai; Mochizuki Hideki; Osaka Hitoshi; Hayakawa Hideki; Ichihara Nobutsune; Li Hang; Furuta Akiko; Sano Yae; Sun Ying-Jie; Kwon Jungkee; Kabuta Tomohiro; Yoshimi Kenji; Aoki Shunsuke; Mizuno Yoshikuni; Noda Mami; Wada Keiji
Dopaminergic neuronal loss in transgenic mice expressing the Parkinson's disease-associated UCH-L1 I93M mutant.
Neurochemistry international 2007;50(1):119-29.
2007: Mizuno Yoshikuni; Hattori Nobutaka; Mochizuki Hideki
Genetic aspects of Parkinson's disease.
Handbook of clinical neurology / edited by P.J. Vinken and G.W. Bruyn 2007;83():217-44.
2007: Tani Momo; Natori Shihoko; Noda Kazuyuki; Fujishima Kenji; Hattori Nobutaka; Mizuno Yoshikuni; Okuma Yasuyuki
Isolated reversible splenial lesion in adult meningitis: a case report and review of the literature.
Internal medicine (Tokyo, Japan) 2007;46(18):1597-600.
2006: Yamakawa Kazuo; Takanashi Masashi; Watanabe Masao; Nakamura Noriyuki; Kobayashi Tomonori; Hasegawa Masato; Mizuno Yoshikuni; Tanaka Shigeki; Mori Hideo
Pathological and biochemical studies on a case of Pick disease with severe white matter atrophy.
Neuropathology : official journal of the Japanese Society of Neuropathology 2006;26(6):586-91.
2006: Nishioka Kenya; Fujishima Kenji; Kobayashi Hirokazu; Mizuno Yoshikuni; Okuma Yasuyuki
An extremely unusual presentation of varicella zoster viral infection of cranial nerves mimicking Garcin syndrome.
Clinical neurology and neurosurgery 2006;108(8):772-4.
2006: Cao Xu-Qing; Arai Hiroyuki; Ren Yong-Ri; Oizumi Hideki; Zhang Ning; Seike Shiho; Furuya Tsuyoshi; Yasuda Toru; Mizuno Yoshikuni; Mochizuki Hideki
Recombinant human granulocyte colony-stimulating factor protects against MPTP-induced dopaminergic cell death in mice by altering Bcl-2/Bax expression levels.
Journal of neurochemistry 2006;99(3):861-7.
2006: Sato Shigeto; Chiba Tomoki; Nishiyama Shingo; Kakiuchi Takeharu; Tsukada Hideo; Hatano Taku; Fukuda Takahiro; Yasoshima Yasunobu; Kai Nobuyuki; Kobayashi Kazuto; Mizuno Yoshikuni; Tanaka Keiji; Hattori Nobutaka
Decline of striatal dopamine release in parkin-deficient mice shown by ex vivo autoradiography.
Journal of neuroscience research 2006;84(6):1350-7.
2006: Nakamura Atsuko; Kitami Toshiaki; Mori Hideo; Mizuno Yoshikuni; Hattori Nobutaka
Nuclear localization of the 20S proteasome subunit in Parkinson's disease.
Neuroscience letters 2006;406(1-2):43-8.
2006: Wada Makoto; Yoshimi Kenji; Higo Noriyuki; Ren Yong-Ri; Mochizuki Hideki; Mizuno Yoshikuni; Kitazawa Shigeru
Statistical parametric mapping of immunopositive cell density.
Neuroscience research 2006;56(1):96-102.
2006: Ren Yong-Ri; Nishida Yoichiro; Yoshimi Kenji; Yasuda Toru; Jishage Kou-Ichi; Uchihara Toshiki; Yokota Takanori; Mizuno Yoshikuni; Mochizuki Hideki
Genetic vitamin E deficiency does not affect MPTP susceptibility in the mouse brain.
Journal of neurochemistry 2006;98(6):1810-6.
2006: Sato Kenichi; Hatano Taku; Yamashiro Kazuo; Kagohashi Maki; Nishioka Kenya; Izawa Nana; Mochizuki Hideki; Hattori Nobutaka; Mori Hideo; Mizuno Yoshikuni;
Prognosis of Parkinson's disease: time to stage III, IV, V, and to motor fluctuations.
Movement disorders : official journal of the Movement Disorder Society 2006;21(9):1384-95.
2006: Arai Takeo; Fukae Jiro; Hatano Taku; Kubo Shin-ichiro; Ohtsubo Toshio; Nakabeppu Yusaku; Mori Hideo; Mizuno Yoshikuni; Hattori Nobutaka
Up-regulation of hMUTYH, a DNA repair enzyme, in the mitochondria of substantia nigra in Parkinson's disease.
Acta neuropathologica 2006;112(2):139-45.
2006: Tomiyama Hiroyuki; Li Yuanzhe; Funayama Manabu; Hasegawa Kazuko; Yoshino Hiroyo; Kubo Shin-Ichiro; Sato Kenichi; Hattori Tatsuya; Lu Chin-Song; Inzelberg Rivka; Djaldetti Ruth; Melamed Eldad; Amouri Rim; Gouider-Khouja Neziha; Hentati Faycal; Hatano Yasuko; Wang Mei; Imamichi Yoko; Mizoguchi Koichi; Miyajima Hiroaki; Obata Fumiya; Toda Tatsushi; Farrer Matthew J; Mizuno Yoshikuni; Hattori Nobutaka
Clinicogenetic study of mutations in LRRK2 exon 41 in Parkinson's disease patients from 18 countries.
Movement disorders : official journal of the Movement Disorder Society 2006;21(8):1102-8.
2006: Kubo Shin-ichiro; Hattori Nobutaka; Mizuno Yoshikuni
Recessive Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2006;21(7):885-93.
2006: Watanabe Terubumi; Zhang Ning; Liu Meizi; Tanaka Ryota; Mizuno Yoshikuni; Urabe Takao
Cilostazol protects against brain white matter damage and cognitive impairment in a rat model of chronic cerebral hypoperfusion.
Stroke; a journal of cerebral circulation 2006;37(6):1539-45.
2006: Ueno Yuji; Fujishima Kenji; Kobayashi Hirokazu; Mizuno Yoshikuni; Okuma Yasuyuki
Cortical myoclonus due to hypocalcemia 12 years after thyroidectomy.
Clinical neurology and neurosurgery 2006;108(4):400-3.
2006: Arai H; Furuya T; Mizuno Y; Mochizuki H
Inflammation and infection in Parkinson's disease.
Histology and histopathology 2006;21(6):673-8.
2006: Wada Keiichirou; Arai Hiroyuki; Takanashi Masashi; Fukae Jiro; Oizumi Hideki; Yasuda Toru; Mizuno Yoshikuni; Mochizuki Hideki
Expression levels of vascular endothelial growth factor and its receptors in Parkinson's disease.
Neuroreport 2006;17(7):705-9.
2006: Yamamoto Shoji; Fukae Jiro; Mori Hideo; Mizuno Yoshikuni; Hattori Nobutaka
Positive immunoreactivity for vesicular monoamine transporter 2 in Lewy bodies and Lewy neurites in substantia nigra.
Neuroscience letters 2006;396(3):187-91.
2006: Hatano Taku; Fukuda Momo; Shiotsuki Hiromi; Miwa Hideto; Urabe Takao; Mizuno Yoshikuni
[Chronic inflammatory demyelinating polyneuropathy followed by systemic lupus erythematosus and Sjögren syndrome: a case report]
Rinsho shinkeigaku = Clinical neurology 2006;46(3):203-9.
2006: Hayashita-Kinoh Hiromi; Yamada Masanori; Yokota Takanori; Mizuno Yoshikuni; Mochizuki Hideki
Down-regulation of alpha-synuclein expression can rescue dopaminergic cells from cell death in the substantia nigra of Parkinson's disease rat model.
Biochemical and biophysical research communications 2006;341(4):1088-95.
2006: Komine-Kobayashi Miki; Zhang Ning; Liu Meizi; Tanaka Ryota; Hara Hideaki; Osaka Akimichi; Mochizuki Hideki; Mizuno Yoshikuni; Urabe Takao
Neuroprotective effect of recombinant human granulocyte colony-stimulating factor in transient focal ischemia of mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(3):402-13.
2006: Watanabe Terubumi; Goto Keigo; Takanashi Masashi; Mori Hideo; Fujii Hiroaki; Hino Okio; Mochizuki Hideki; Mizuno Yoshikuni
[An 80-year-old woman with progressive stroke, who had rheumatoid arthritis and antiphospholipid syndrome]
No to shinkei = Brain and nerve 2006;58(2):173-81.
2006: Liu Ruiqin; Suzuki Asuka; Guo Zhiwei; Mizuno Yoshikuni; Urabe Takao
Intrinsic and extrinsic erythropoietin enhances neuroprotection against ischemia and reperfusion injury in vitro.
Journal of neurochemistry 2006;96(4):1101-10.
2006: Nishioka Kenya; Hayashi Shin; Farrer Matthew J; Singleton Andrew B; Yoshino Hiroyo; Imai Hisamasa; Kitami Toshiaki; Sato Kenichi; Kuroda Ryu; Tomiyama Hiroyuki; Mizoguchi Koichi; Murata Miho; Toda Tatsushi; Imoto Issei; Inazawa Johji; Mizuno Yoshikuni; Hattori Nobutaka
Clinical heterogeneity of alpha-synuclein gene duplication in Parkinson's disease.
Annals of neurology 2006;59(2):298-309.
2006: Matsuda Noriyuki; Kitami Toshiaki; Suzuki Toshiaki; Mizuno Yoshikuni; Hattori Nobutaka; Tanaka Keiji
Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro.
The Journal of biological chemistry 2006;281(6):3204-9.
2006: Wada Keiichiro; Motoi Yumiko; Komatsuzaki Yasuko; Takanashi Masashi; Mori Hideo; Urabe Takao; Mizuno Yoshikuni
[An 81-year-old man with personality change, dementia, and gait disturbance with diffuse leukoaraiosis of the cerebral white matter]
No to shinkei = Brain and nerve 2006;58(1):79-90.
2006: Kitami Makiko-Iijima; Kitami Toshiaki; Nagahama Masami; Tagaya Mitsuo; Hori Seiji; Kakizuka Akira; Mizuno Yoshikuni; Hattori Nobutaka
Dominant-negative effect of mutant valosin-containing protein in aggresome formation.
FEBS letters 2006;580(2):474-8.
2006: Naito Sachio; Mochizuki Hideki; Yasuda Toru; Mizuno Yoshikuni; Furusaka Michihiro; Ikeda Susumu; Adachi Tomohiro; Shimizu Hirohiko M; Suzuki Junichi; Fujiwara Satoru; Okada Tomoko; Nishikawa Kaori; Aoki Shunsuke; Wada Keiji
Characterization of multimetric variants of ubiquitin carboxyl-terminal hydrolase L1 in water by small-angle neutron scattering.
Biochemical and biophysical research communications 2006;339(2):717-25.
2006: Sato Shigeto; Chiba Tomoki; Sakata Eri; Kato Koichi; Mizuno Yoshikuni; Hattori Nobutaka; Tanaka Keiji
14-3-3eta is a novel regulator of parkin ubiquitin ligase.
The EMBO journal 2006;25(1):211-21.
2006: Mochizuki H; Yamada M; Mizuno Y
Alpha-synuclein overexpression model.
Journal of neural transmission. Supplementum 2006;(70):281-4.
2006: Hattori N; Machida Y; Sato S; Noda K; Iijima-Kitami M; Kubo S; Mizuno Y
Molecular mechanisms of nigral neurodegeneration in Park2 and regulation of parkin protein by other proteins.
Journal of neural transmission. Supplementum 2006;(70):205-8.
2006: Mizuno Y; Hattori N; Yoshino H; Hatano Y; Satoh K; Tomiyama H; Li Y
Progress in familial Parkinson's disease.
Journal of neural transmission. Supplementum 2006;(70):191-204.
2006: Yamashiro Kazuo; Watanabe Terubumi; Tanaka Ryota; Komine-Kobayashi Miki; Mizuno Yoshikuni; Urabe Takao
Clustering of risk factors increases the incidence of echolucent carotid plaque in stroke patients.
Cerebrovascular diseases (Basel, Switzerland) 2006;22(5-6):432-8.
2006: Miyamoto Nobukazu; Kagohashi Maki; Nishioka Kenya; Fujishima Kenji; Kitada Tohru; Tomita Yoshiyuki; Mori Kentaro; Maeda Minoru; Wada Ryo; Matsumoto Michio; Mori Hideo; Mizuno Yoshikuni; Okuma Yasuyuki
An autopsy case of Schilder's variant of multiple sclerosis (Schilder's disease).
European neurology 2006;55(2):103-7.
2005: Shimura Hideki; Mori Hideo; Komatsuzaki Yasuko; Nakamura Kazuhiro; Takanashi Masashi; Hattori Nobutaka; Mizuno Yoshikuni
[A 54-year-old man with familial parkinsonism, gaze palsy, and dementia]
No to shinkei = Brain and nerve 2005;57(12):1104-12.
2005: Inzelberg Rivka; Hattori Nobutaka; Mizuno Yoshikuni
Dopaminergic dysfunction in unrelated, asymptomatic carriers of a single parkin mutation.
Neurology 2005;65(11):1843.
2005: Li Xiaobing; Kitami Toshiaki; Wang Mei; Mizuno Yoshikuni; Hattori Nobutaka
Geographic and ethnic differences in frequencies of two polymorphisms (D/N394 and L/I272) of the parkin gene in sporadic Parkinson's disease.
Parkinsonism & related disorders 2005;11(8):485-91.
2005: McKeith I G; Dickson D W; Lowe J; Emre M; O'Brien J T; Feldman H; Cummings J; Duda J E; Lippa C; Perry E K; Aarsland D; Arai H; Ballard C G; Boeve B; Burn D J; Costa D; Del Ser T; Dubois B; Galasko D; Gauthier S; Goetz C G; Gomez-Tortosa E; Halliday G; Hansen L A; Hardy J; Iwatsubo T; Kalaria R N; Kaufer D; Kenny R A; Korczyn A; Kosaka K; Lee V M Y; Lees A; Litvan I; Londos E; Lopez O L; Minoshima S; Mizuno Y; Molina J A; Mukaetova-Ladinska E B; Pasquier F; Perry R H; Schulz J B; Trojanowski J Q; Yamada M;
Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium.
Neurology 2005;65(12):1863-72.
2005: Shimo Yasuji; Sato Kennichi; Iwamoto Hiroyuki; Motoi Yumiko; Mori Hideo; Urabe Takao; Mizuno Yoshikuni
[A 76-year-old woman with personality change, dementia and parkinsonism]
No to shinkei = Brain and nerve 2005;57(11):1011-9.
2005: Oyama Genko; Izawa Nana; Fujishima Kenji; Kobayashi Hirokazu; Mizuno Yoshikuni; Okuma Yasuyuki
[Familial amyotrophic lateral sclerosis with rapid progression]
No to shinkei = Brain and nerve 2005;57(11):1003-6.
2005: Orr Carolyn F; Rowe Dominic B; Mizuno Yoshikuni; Mori Hideo; Halliday Glenda M
A possible role for humoral immunity in the pathogenesis of Parkinson's disease.
Brain : a journal of neurology 2005;128(Pt 11):2665-74.
2005: Hatano Taku; Takanashi Masashi; Sumino Teiko; Liu Ying; Mori Hideo; Hattori Nobutaka; Mizuno Yoshikuni
[A 73-year-old woman with depression, dementia, and parkinsonism]
No to shinkei = Brain and nerve 2005;57(10):907-14.
2005: Namba Takashi; Mochizuki Hideki; Onodera Masafumi; Mizuno Yoshikuni; Namiki Hideo; Seki Tatsunori
The fate of neural progenitor cells expressing astrocytic and radial glial markers in the postnatal rat dentate gyrus.
The European journal of neuroscience 2005;22(8):1928-41.
2005: Zhang Ning; Komine-Kobayashi Miki; Tanaka Ryota; Liu Meizi; Mizuno Yoshikuni; Urabe Takao
Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal ischemia in mice brain.
Stroke; a journal of cerebral circulation 2005;36(10):2220-5.
2005: Motoi Yumiko; Iwamoto Hiroyuki; Itaya Masako; Kobayashi Tomonori; Hasegawa Masato; Yasuda Minoru; Mizuno Yoshikuni; Mori Hideo
Four-repeat tau-positive Pick body-like inclusions are distinct from classic Pick bodies.
Acta neuropathologica 2005;110(4):431-3.
2005: Ide Masayuki; Yamada Kazuo; Toyota Tomoko; Iwayama Yoshimi; Ishitsuka Yuichi; Minabe Yoshio; Nakamura Kazuhiko; Hattori Nobutaka; Asada Takashi; Mizuno Yoshikuni; Mori Norio; Yoshikawa Takeo
Genetic association analyses of PHOX2B and ASCL1 in neuropsychiatric disorders: evidence for association of ASCL1 with Parkinson's disease.
Human genetics 2005;117(6):520-7.
2005: Orimo Satoshi; Amino Takeshi; Yokochi Masayuki; Kojo Tohru; Uchihara Toshiki; Takahashi Atsushi; Wakabayashi Koichi; Takahashi Hitoshi; Hattori Nobutaka; Mizuno Yoshikuni
Preserved cardiac sympathetic nerve accounts for normal cardiac uptake of MIBG in PARK2.
Movement disorders : official journal of the Movement Disorder Society 2005;20(10):1350-3.
2005: Fukae Jiro; Motoi Yumiko; Komatsuzaki Yasuko; Takanashi Masashi; Mochizuki Hideki; Mizuno Yoshikuni
[A 59-year-old woman with personality change and abnormal behavior followed by amyotrophy and dementia]
No to shinkei = Brain and nerve 2005;57(9):810-20.
2005: Mizuno Yoshikuni
[In pursuit of the causes for Parkinson disease]
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2005;94(9):1761-73.
2005: Kubo Shin-ichiro; Nemani Venu M; Chalkley Robert J; Anthony Malcolm D; Hattori Nobutaka; Mizuno Yoshikuni; Edwards Robert H; Fortin Doris L
A combinatorial code for the interaction of alpha-synuclein with membranes.
The Journal of biological chemistry 2005;280(36):31664-72.
2005: Machida Yuh; Lijima Makiko; Nakamura Kazuhiro; Ota Satoshi; Hattori Nobutaka; Mizuno Yoshikuni
[A 60-year-old man with intention tremor as an initial symptom followed by cerebellar ataxia, peripheral neuropathy and dementia]
No to shinkei = Brain and nerve 2005;57(8):710-9.
2005: Guo Li; Itaya Masako; Takanashi Masashi; Mizuno Yoshikuni; Mori Hideo
Relationship between Parkinson disease with dementia and dementia with Lewy bodies.
Parkinsonism & related disorders 2005;11(5):305-9.
2005: Yoshimi Kenji; Ren Yong-Ri; Seki Tatsunori; Yamada Masanori; Ooizumi Hideki; Onodera Masafumi; Saito Yuko; Murayama Shigeo; Okano Hideyuki; Mizuno Yoshikuni; Mochizuki Hideki
Possibility for neurogenesis in substantia nigra of parkinsonian brain.
Annals of neurology 2005;58(1):31-40.
2005: Fukae Jiro; Kubo Shin-Ichiro; Hattori Nobutaka; Komatsu Kaoru; Kato Masaaki; Aoki Masashi; Mizuno Yoshikuni
Hoarseness due to bilateral vocal cord paralysis as an initial manifestation of familial amyotrophic lateral sclerosis.
Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 2005;6(2):122-4.
2005: Li Y; Tomiyama H; Sato K; Hatano Y; Yoshino H; Atsumi M; Kitaguchi M; Sasaki S; Kawaguchi S; Miyajima H; Toda T; Mizuno Y; Hattori N
Clinicogenetic study of PINK1 mutations in autosomal recessive early-onset parkinsonism.
Neurology 2005;64(11):1955-7.
2005: Machida Yutaka; Chiba Tomoki; Takayanagi Atsushi; Tanaka Yoshikazu; Asanuma Masato; Ogawa Norio; Koyama Akihiko; Iwatsubo Takeshi; Ito Shosuke; Jansen Poul Hening; Shimizu Nobuyoshi; Tanaka Keiji; Mizuno Yoshikuni; Hattori Nobutaka
Common anti-apoptotic roles of parkin and alpha-synuclein in human dopaminergic cells.
Biochemical and biophysical research communications 2005;332(1):233-40.
2005: Fukae Jiro; Mochizuki Hideki; Ohashi Rina; Mitani Kazuko; Kawada Junya; Mizuno Yoshikuni
[Late onset hemiparkinsonism-hemiatrophy syndrome: a case report]
Rinsho shinkeigaku = Clinical neurology 2005;45(5):390-3.
2005: Noda Kazuyuki; Kitami Toshiaki; Gai Wei Ping; Chegini Fariba; Jensen Poul Henning; Fujimura Tsutomu; Murayama Kimie; Tanaka Keiji; Mizuno Yoshikuni; Hattori Nobutaka
Phosphorylated IkappaBalpha is a component of Lewy body of Parkinson's disease.
Biochemical and biophysical research communications 2005;331(1):309-17.
2005: Hatano Yasuko; Ri Gyohyo; Hattori Nobutaka; Mizuno Yoshikuni
[Gene abnormalities in Parkinson disease]
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2005;94(4):775-81.
2005: Ichikawa Naoki; Kasai Shingo; Suzuki Nobuharu; Nishi Norio; Oishi Shinya; Fujii Nobutaka; Kadoya Yuichi; Hatori Kozo; Mizuno Yoshikuni; Nomizu Motoyoshi; Arikawa-Hirasawa Eri
Identification of neurite outgrowth active sites on the laminin alpha4 chain G domain.
Biochemistry 2005;44(15):5755-62.
2005: Okuma Yasuyuki; Fujishima Kenji; Miwa Hideto; Mori Hideo; Mizuno Yoshikuni
Myoclonic tremulous movements in multiple system atrophy are a form of cortical myoclonus.
Movement disorders : official journal of the Movement Disorder Society 2005;20(4):451-6.
2005: Kobayashi Miki; Hatano Taku; Tanaka Shigeki; Ishi Kazuhisa; Takanashi Masashi; Urabe Takao; Mizuno Yoshikuni
[A 67-year-old man with rt. hand resting tremor and rigidity after lt. putaminal hemorrhage]
No to shinkei = Brain and nerve 2005;57(3):243-53.
2005: Fukae Jiro; Takanashi Masashi; Kubo Shin-ichiro; Nishioka Ken-ichi; Nakabeppu Yusaku; Mori Hideo; Mizuno Yoshikuni; Hattori Nobutaka
Expression of 8-oxoguanine DNA glycosylase (OGG1) in Parkinson's disease and related neurodegenerative disorders.
Acta neuropathologica 2005;109(3):256-62.
2005: Sato Shigeto; Mizuno Yoshikuni; Hattori Nobutaka
Urinary 8-hydroxydeoxyguanosine levels as a biomarker for progression of Parkinson disease.
Neurology 2005;64(6):1081-3.
2005: Mizuno Yoshikuni
[Studies on pathogenesis of Parkinson's disease]
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2005;94 Suppl():66-70.
2005: Yamada Masanori; Mizuno Yoshikuni; Mochizuki Hideki
Parkin gene therapy for alpha-synucleinopathy: a rat model of Parkinson's disease.
Human gene therapy 2005;16(2):262-70.
2005: Noda Kazuyuki; Kobayashi Tomonori; Matsuoka Shuji; Takanashi Masashi; Kanazawa Akira; Mizuno Yoshikuni
[A 65-year-old man with rigid-bradykinetic parkinsonism, vertical gaze palsy, difficulty of eye-lid opening, and marked pseudo-bulbar palsy]
No to shinkei = Brain and nerve 2005;57(1):73-86.
2005: Yamashiro Kazuo; Kunoki Makiko; Miura Yoshiharu; Tomiyama Junji; Mochizuki Hideki; Mizuno Yoshikuni
[Posterior leukoencephalopathy syndrome presenting with bilateral ataxie optique: a case report]
Rinsho shinkeigaku = Clinical neurology 2005;45(1):13-7.
2005: Tsuchiya Katsumi; Tajima Hisao; Kuwae Toyoyasu; Takeshima Takao; Nakano Toshiya; Tanaka Masaharu; Sunaga Katsuyoshi; Fukuhara Yoko; Nakashima Kenji; Ohama Eisaku; Mochizuki Hideki; Mizuno Yoshikuni; Katsube Nobuo; Ishitani Ryoichi
Pro-apoptotic protein glyceraldehyde-3-phosphate dehydrogenase promotes the formation of Lewy body-like inclusions.
The European journal of neuroscience 2005;21(2):317-26.
2005: Moore Darren J; Zhang Li; Troncoso Juan; Lee Michael K; Hattori Nobutaka; Mizuno Yoshikuni; Dawson Ted M; Dawson Valina L
Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress.
Human molecular genetics 2005;14(1):71-84.
2004: Arai Hiroyuki; Furuya Tsuyoshi; Yasuda Toru; Miura Masayuki; Mizuno Yoshikuni; Mochizuki Hideki
Neurotoxic effects of lipopolysaccharide on nigral dopaminergic neurons are mediated by microglial activation, interleukin-1beta, and expression of caspase-11 in mice.
The Journal of biological chemistry 2004;279(49):51647-53.
2004: Mizuno Yoshikuni
[Progress in the basic and clinical aspects of Parkinson's disease]
Rinsho shinkeigaku = Clinical neurology 2004;44(11):741-50.
2004: Tanaka Keiji; Suzuki Toshiaki; Hattori Nobutaka; Mizuno Yoshikuni
Ubiquitin, proteasome and parkin.
Biochimica et biophysica acta 2004;1695(1-3):235-47.
2004: Hatano Y; Sato K; Elibol B; Yoshino H; Yamamura Y; Bonifati V; Shinotoh H; Asahina M; Kobayashi S; Ng A R; Rosales R L; Hassin-Baer S; Shinar Y; Lu C S; Chang H C; Wu-Chou Y H; Ataç F B; Kobayashi T; Toda T; Mizuno Y; Hattori N
PARK6-linked autosomal recessive early-onset parkinsonism in Asian populations.
Neurology 2004;63(8):1482-5.
2004: Tanaka Masashi; Cabrera Vicente M; González Ana M; Larruga José M; Takeyasu Takeshi; Fuku Noriyuki; Guo Li-Jun; Hirose Raita; Fujita Yasunori; Kurata Miyuki; Shinoda Ken-ichi; Umetsu Kazuo; Yamada Yoshiji; Oshida Yoshiharu; Sato Yuzo; Hattori Nobutaka; Mizuno Yoshikuni; Arai Yasumichi; Hirose Nobuyoshi; Ohta Shigeo; Ogawa Osamu; Tanaka Yasushi; Kawamori Ryuzo; Shamoto-Nagai Masayo; Maruyama Wakako; Shimokata Hiroshi; Suzuki Ryota; Shimodaira Hidetoshi
Mitochondrial genome variation in eastern Asia and the peopling of Japan.
Genome research 2004;14(10A):1832-50.
2004: Yamada Masanori; Iwatsubo Takeshi; Mizuno Yoshikuni; Mochizuki Hideki
Overexpression of alpha-synuclein in rat substantia nigra results in loss of dopaminergic neurons, phosphorylation of alpha-synuclein and activation of caspase-9: resemblance to pathogenetic changes in Parkinson's disease.
Journal of neurochemistry 2004;91(2):451-61.
2004: Mizuno Yoshikuni
[Progress in Parkinson's disease]
Nippon rinsho. Japanese journal of clinical medicine 2004;62(9):1597-600.
2004: Olanow C Warren; Agid Yves; Mizuno Yoshi; Albanese Alberto; Bonuccelli Ubaldo; Damier Philip; De Yebenes Justo; Gershanik Oscar; Guttman Mark; Grandas F; Hallett Mark; Hornykiewicz Ole; Jenner Peter; Katzenschlager R; Langston William J; LeWitt Peter; Melamed Eldad; Mena M A; Michel P P; Mytilineou Catherine; Obeso Jose A; Poewe Werner; Quinn Niall; Raisman-Vozari R; Rajput Ali H; Rascol Olivier; Sampaio Christina; Stocchi Fabrizio
Levodopa in the treatment of Parkinson's disease: current controversies.
Movement disorders : official journal of the Movement Disorder Society 2004;19(9):997-1005.
2004: Motoi Yumiko; Itaya Masako; Mori Hideo; Mizuno Yoshikuni; Iwasaki Tadao; Hattori Hiroaki; Haga Seichi; Ikeda Kazuhiko
Apolipoprotein E receptor 2 is involved in neuritic plaque formation in APP sw mice.
Neuroscience letters 2004;368(2):144-7.
2004: Hatano Yasuko; Li Yuanzhe; Sato Kenichi; Asakawa Shuichi; Yamamura Yasuhiro; Tomiyama Hiroyuki; Yoshino Hiroyo; Asahina Masato; Kobayashi Susumu; Hassin-Baer Sharon; Lu Chin-Song; Ng Arlene R; Rosales Raymond L; Shimizu Nobuyoshi; Toda Tatsushi; Mizuno Yoshikuni; Hattori Nobutaka
Novel PINK1 mutations in early-onset parkinsonism.
Annals of neurology 2004;56(3):424-7.
2004: Hattori Nobutaka; Mizuno Yoshikuni
Pathogenetic mechanisms of parkin in Parkinson's disease.
Lancet 2004;364(9435):722-4.
2004: Calne Donald B; Mizuno Yoshikuni
The neuromythology of Parkinson's Disease.
Parkinsonism & related disorders 2004;10(5):319-22.
2004: Shimo-Nakanishi Yumi; Hasebe Takeshi; Suzuki Asuka; Mochizuki Hideki; Nomiyama Takashi; Tanaka Yasushi; Nagaoka Isao; Mizuno Yoshikuni; Urabe Takao
Functional effects of NAD(P)H oxidase p22(phox) C242T mutation in human leukocytes and association with thrombotic cerebral infarction.
Atherosclerosis 2004;175(1):109-15.
2004: Higashi Youichirou; Asanuma Masato; Miyazaki Ikuko; Hattori Nobutaka; Mizuno Yoshikuni; Ogawa Norio
Parkin attenuates manganese-induced dopaminergic cell death.
Journal of neurochemistry 2004;89(6):1490-7.
2004: Tanaka Ryota; Yamashiro Kazuo; Mochizuki Hideki; Cho Nei; Onodera Masafumi; Mizuno Yoshikuni; Urabe Takao
Neurogenesis after transient global ischemia in the adult hippocampus visualized by improved retroviral vector.
Stroke; a journal of cerebral circulation 2004;35(6):1454-9.
2004: Komine-Kobayashi Miki; Chou Nei; Mochizuki Hideki; Nakao Atsuhito; Mizuno Yoshikuni; Urabe Takao
Dual role of Fcgamma receptor in transient focal cerebral ischemia in mice.
Stroke; a journal of cerebral circulation 2004;35(4):958-63.
2004: Motoi Yumiko; Takanashi Masashi; Itaya Masako; Ikeda Kazuhiko; Mizuno Yoshikuni; Mori Hideo
Glial localization of four-repeat tau in atypical progressive supranuclear palsy.
Neuropathology : official journal of the Japanese Society of Neuropathology 2004;24(1):60-5.
2004: Kagohashi Maki; Okuma Yasuyuki; Fujishima Kenji; Kitada Tohru; Mizuno Yoshikuni
Blepharospasm associated with multiple system atrophy: a case report and review of the literature.
Parkinsonism & related disorders 2004;10(3):169-71.
2004: Furuya Tsuyoshi; Hayakawa Hideki; Yamada Masanori; Yoshimi Kenji; Hisahara Shin; Miura Masayuki; Mizuno Yoshikuni; Mochizuki Hideki
Caspase-11 mediates inflammatory dopaminergic cell death in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(8):1865-72.
2004: Watanabe Terubumi; Okuma Yasuyuki; Fujishima Kenji; Kitada Tohru; Nakao Yasuaki; Mizuno Yoshikuni
Isolated deep cerebral venous thrombosis: an important cause for isolated mental impairment.
European neurology 2004;52(2):123-5.
2004: Yamada M; Onodera M; Mizuno Y; Mochizuki H
Neurogenesis in olfactory bulb identified by retroviral labeling in normal and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated adult mice.
Neuroscience 2004;124(1):173-81.
2004: Yamashiro Kazuo; Okuma Yasuyuki; Fujishima Kenji; Goto Keigo; Mizuno Yoshikuni
Bilateral hypoglossal nerve involvement in chronic inflammatory demyelinating polyneuropathy.
European neurology 2004;51(1):45-6.
2003: Hattori Yuko; Hattori Tatsuya; Mukai Ei-ichiro; Mori Hideo; Mizuno Yoshikuni; Kayukawa Yuhei; Okada Tamotsu; Kanbayashi Takashi
[Excessive daytime sleepiness and low CSF orexin-A/hypocretin-I levels in a patient with probable progressive supranuclear palsy]
No to shinkei = Brain and nerve 2003;55(12):1053-6.
2003: Nagano Yoshito; Yamashita Hiroshi; Takahashi Tetsuya; Kishida Shosei; Nakamura Takeshi; Iseki Eizo; Hattori Nobutaka; Mizuno Yoshikuni; Kikuchi Akira; Matsumoto Masayasu
Siah-1 facilitates ubiquitination and degradation of synphilin-1.
The Journal of biological chemistry 2003;278(51):51504-14.
2003: Hattori Nobutaka; Kobayashi Hirokazu; Sasaki-Hatano Yasuko; Sato Kenichi; Mizuno Yoshikuni
Familial Parkinson's disease: a hint to elucidate the mechanisms of nigral degeneration.
Journal of neurology 2003;250 Suppl 3():III2-10.
2003: Mizuno Yoshikuni; Yanagisawa Nobuo; Kuno Sadako; Yamamoto Mitsutoshi; Hasegawa Kazuko; Origasa Hideki; Kowa Hisayuki;
Randomized, double-blind study of pramipexole with placebo and bromocriptine in advanced Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2003;18(10):1149-56.
2003: Hatano T; Okuma Y; Iijima M; Fujishima K; Goto K; Mizuno Y
Cervical dystonia in dentatorubral-pallidoluysian atrophy.
Acta neurologica Scandinavica 2003;108(4):287-9.
2003: Kim Se Jung; Sung Jee Young; Um Ji Won; Hattori Nobutaka; Mizuno Yoshikuni; Tanaka Keiji; Paik Seung R; Kim Jongsun; Chung Kwang Chul
Parkin cleaves intracellular alpha-synuclein inclusions via the activation of calpain.
The Journal of biological chemistry 2003;278(43):41890-9.
2003: Hattori Nobutaka; Hatano Yasuko; Sato Kenichi; Mizuno Yoshikuni
[Juvenile parkinsonism]
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2003;92(8):1406-13.
2003: Hatano Yasuko; Mori Hideo; Kakusaka Kaoru; Kitada Toru; Urabe Takao; Mizuno Yoshikuni
[A patient with Hashimoto's encephalopathy showing subacute global cognitive dysfunction]
Rinsho shinkeigaku = Clinical neurology 2003;43(6):360-2.
2003: Takahashi Ryosuke; Imai Yuzuru; Hattori Nobutaka; Mizuno Yoshikuni
Parkin and endoplasmic reticulum stress.
Annals of the New York Academy of Sciences 2003;991():101-6.
2003: Okuma Yasuyuki; Hattori Nobutaka; Mizuno Yoshikuni
Sensory neuropathy in autosomal recessive juvenile parkinsonism (PARK2).
Parkinsonism & related disorders 2003;9(5):313-4.
2003: Gouider-Khouja Neziha; Larnaout Abdelmajid; Amouri Rim; Sfar Sana; Belal Samir; Ben Hamida Christiane; Ben Hamida Mongi; Hattori Nobutaka; Mizuno Yoshikuni; Hentati Fayçal
Autosomal recessive parkinsonism linked to parkin gene in a Tunisian family. Clinical, genetic and pathological study.
Parkinsonism & related disorders 2003;9(5):247-51.
2003: Ikebe Shin-ichiro; Harada Toshiaki; Hashimoto Takao; Kanazawa Ichiro; Kuno Sadako; Mizuno Yoshikuni; Mizuta Eiji; Murata Miho; Nagatsu Toshiharu; Nakamura Shigenobu; Takubo Hideki; Yanagisawa Nobuo; Narabayashi Hirotaro
Prevention and treatment of malignant syndrome in Parkinson's disease: a consensus statement of the malignant syndrome research group.
Parkinsonism & related disorders 2003;9 Suppl 1():S47-9.
2003: Takubo Hideki; Shimoda-Matsubayashi Satoe; Mizuno Yoshikuni
Serum creatine kinase is elevated in patients with Parkinson's disease: a case controlled study.
Parkinsonism & related disorders 2003;9 Suppl 1():S43-6.
2003: Takubo Hideki; Harada Toshihide; Hashimoto Takao; Inaba Yutaka; Kanazawa Ichiro; Kuno Sadako; Mizuno Yoshikuni; Mizuta Eiji; Murata Miho; Nagatsu Toshiharu; Nakamura Shigenobu; Yanagisawa Nobuo; Narabayashi Hirotaro
A collaborative study on the malignant syndrome in Parkinson's disease and related disorders.
Parkinsonism & related disorders 2003;9 Suppl 1():S31-41.
2003: Mizuno Yoshikuni; Takubo Hideki; Mizuta Eiiji; Kuno Sadako
Malignant syndrome in Parkinson's disease: concept and review of the literature.
Parkinsonism & related disorders 2003;9 Suppl 1():S3-9.
2003: Narabayashi H; Mizuno Y
Preface: Malignant syndrome in Parkinson's disease.
Parkinsonism & related disorders 2003;9 Suppl 1():S1.
2003: Inzelberg R; Hattori N; Nisipeanu P; Abo Mouch S; Blumen S C; Carasso R L; Mizuno Y
Camptocormia, axial dystonia, and parkinsonism: phenotypic heterogeneity of a parkin mutation.
Neurology 2003;60(8):1393-4.
2003: Rawal N; Periquet M; Lohmann E; Lücking C B; Teive H A; Ambrosio G; Raskin S; Lincoln S; Hattori N; Guimaraes J; Horstink M W I M; Dos Santos Bele W; Brousolle E; Destée A; Mizuno Y; Farrer M; Deleuze J-F; De Michele G; Agid Y; Dürr A; Brice A;
New parkin mutations and atypical phenotypes in families with autosomal recessive parkinsonism.
Neurology 2003;60(8):1378-81.
2003: Mori Hideo; Hattori Nobutaka; Mizuno Yoshikuni
Genotype-phenotype correlation: familial Parkinson disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2003;23(1):90-4.
2003: Furuya Tsuyoshi; Tanaka Ryota; Urabe Takao; Hayakawa Jun; Migita Makoto; Shimada Takashi; Mizuno Yoshikuni; Mochizuki Hideki
Establishment of modified chimeric mice using GFP bone marrow as a model for neurological disorders.
Neuroreport 2003;14(4):629-31.
2003: Sakata Eri; Yamaguchi Yoshiki; Kurimoto Eiji; Kikuchi Jun; Yokoyama Shigeyuki; Yamada Shingo; Kawahara Hiroyuki; Yokosawa Hideyoshi; Hattori Nobutaka; Mizuno Yoshikuni; Tanaka Keiji; Kato Koichi
Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin-like domain.
EMBO reports 2003;4(3):301-6.
2003: Kobayashi Tomonori; Matsumine Hiroto; Zhang JiaLin; Imamichi Yoko; Mizuno Yoshikuni; Hattori Nobutaka
Pseudo-autosomal dominant inheritance of PARK2: two families with parkin gene mutations.
Journal of the neurological sciences 2003;207(1-2):11-7.
2003: Tsuboi Yoshio; Wszolek Zbigniew K; Mizuno Yoshikuni; Kobayashi Tomonori; Yasuda Minoru; Yamada Tatsuo
[Japanese contribution to the understanding of frontotemporal dementia and parkinsonism linked to chromosome 17(FTDP-17)]
No to shinkei = Brain and nerve 2003;55(2):107-19.
2003: Furuya Tsuyoshi; Namihira Tomoo; Yamazaki Shigetaka; Mori Hideo; Hattori Nobutaka; Mizuno Yoshikuni
[A 65-year-old woman with progressive loss of vision and visual field defects]
No to shinkei = Brain and nerve 2003;55(1):87-96.
2003: Kobayashi Tomonori; Ota Satoru; Tanaka Kuniaki; Ito Yuji; Hasegawa Masato; Umeda Yuri; Motoi Yumiko; Takanashi Masashi; Yasuhara Masahiro; Anno Midori; Mizuno Yoshikuni; Mori Hideo
A novel L266V mutation of the tau gene causes frontotemporal dementia with a unique tau pathology.
Annals of neurology 2003;53(1):133-7.
2003: Kobayashi Hirokazu; Krüger Rejko; Markopoulou Katerina; Wszolek Zbigniew; Chase Bruce; Taka Hikaru; Mineki Reiko; Murayama Kimie; Riess Olaf; Mizuno Yoshikuni; Hattori Nobutaka
Haploinsufficiency at the alpha-synuclein gene underlies phenotypic severity in familial Parkinson's disease.
Brain : a journal of neurology 2003;126(Pt 1):32-42.
2003: Mochizuki H; Mizuno Y
Gene therapy for Parkinson's disease.
Journal of neural transmission. Supplementum 2003;(65):205-13.
2003: Tanaka R; Komine-Kobayashi M; Mochizuki H; Yamada M; Furuya T; Migita M; Shimada T; Mizuno Y; Urabe T
Migration of enhanced green fluorescent protein expressing bone marrow-derived microglia/macrophage into the mouse brain following permanent focal ischemia.
Neuroscience 2003;117(3):531-9.
2002: Kondo Tomoyoshi; Takubo Hideki; Yokochi Fusako; Okuma Yasuyuki; Mizuno Yoshikuni
[Long-term treatment of Parkinson's disease patients with selegiline hydrochloride (FPF 1100): outcome of 5-year treatment]
No to shinkei = Brain and nerve 2002;54(12):1041-8.
2002: Tsuboi Y; Baker M; Hutton M L; Uitti R J; Rascol O; Delisle M-B; Soulages X; Murrell J R; Ghetti B; Yasuda M; Komure O; Kuno S; Arima K; Sunohara N; Kobayashi T; Mizuno Y; Wszolek Z K
Clinical and genetic studies of families with the tau N279K mutation (FTDP-17).
Neurology 2002;59(11):1791-3.
2002: Okuma Yasuyuki; Mizuno Yoshikuni
Absence of linkage to 8q24 in a European family with familial adult myoclonic epilepsy (FAME).
Neurology 2002;59(10):1665; author reply 1665-6.
2002: Tanaka Masashi; Fuku Noriyuki; Takeyasu Takeshi; Guo Li-Jun; Hirose Raita; Kurata Miyuki; Borgeld Harm-Jan W; Yamada Yoshiji; Maruyama Wakako; Arai Yasumichi; Hirose Nobuyoshi; Oshida Yoshiharu; Sato Yuzo; Hattori Nobutaka; Mizuno Yoshikuni; Iwata So; Yagi Kunio
Golden mean to longevity: rareness of mitochondrial cytochrome b variants in centenarians but not in patients with Parkinson's disease.
Journal of neuroscience research 2002;70(3):347-55.
2002: Ohizumi H; Okuma Y; Fukae J; Fujishima K; Goto K; Mizuno Y
Head tremor in dentatorubral-pallidoluysian atrophy.
Acta neurologica Scandinavica 2002;106(5):319-21.
2002: Hirasawa Motoyuki; Ikebe Shin-ichiro; Komatsuzaki Yasuko; Takanashi Masashi; Mori Hideo; Urabe Takao; Mizuno Yoshikuni
[A 52-year-old woman with dyskinesia, epilepsy and gait disturbance]
No to shinkei = Brain and nerve 2002;54(10):919-27.
2002: Iroi Atsuko; Okuma Yasuyuki; Fukae Jiro; Fujishima Kenji; Goto Keigo; Mizuno Yoshikuni
[Amyotrophic lateral sclerosis presented with alexia of kanji and word meaning aphasia]
No to shinkei = Brain and nerve 2002;54(10):903-7.
2002: Mochizuki Hideki; Miura Masauki; Shimada Takashi; Mizuno Yoshikuni
Adeno-associated virus-mediated antiapoptotic gene delivery: in vivo gene therapy for neurological disorders.
Methods (San Diego, Calif.) 2002;28(2):248-52.
2002: Miwa H; Mizuno Y
Enlargements of somatosensory-evoked potentials in progressive supranuclear palsy.
Acta neurologica Scandinavica 2002;106(4):209-12.
2002: Iijima Makiko; Okuma Yasuyuki; Ohizumi Hideki; Fujishima Kenji; Goto Keigo; Mizuno Yoshikuni
[A case of brachial plexus neuropathy who presented with acute paralysis of the hand after sleep]
No to shinkei = Brain and nerve 2002;54(9):819-22.
2002: Mori Hideo; Oda Masaya; Komori Takashi; Arai Nobutaka; Takanashi Masashi; Mizutani Toshio; Hirai Shunnichi; Mizuno Yosikuni
Lewy bodies in progressive supranuclear palsy.
Acta neuropathologica 2002;104(3):273-8.
2002: Mizuno Yoshikuni
[Progress in diagnosis and therapy for Parkinson's disease]
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2002;91(8):2344-8.
2002: Suzuki A; Obi K; Urabe T; Hayakawa H; Yamada M; Kaneko S; Onodera M; Mizuno Y; Mochizuki H
Feasibility of ex vivo gene therapy for neurological disorders using the new retroviral vector GCDNsap packaged in the vesicular stomatitis virus G protein.
Journal of neurochemistry 2002;82(4):953-60.
2002: Agid Y; Olanow C W; Mizuno Y
Levodopa: why the controversy?
Lancet 2002;360(9332):575.
2002: Takanashi Masashi; Mori Hideo; Arima Kunimasa; Mizuno Yoshikuni; Hattori Nobutaka
Expression patterns of tau mRNA isoforms correlate with susceptible lesions in progressive supranuclear palsy and corticobasal degeneration.
Brain research. Molecular brain research 2002;104(2):210-9.
2002: Hyun Dong-Hoon; Lee MoonHee; Hattori Nobutaka; Kubo Shin-Ichiro; Mizuno Yoshikuni; Halliwell Barry; Jenner Peter
Effect of wild-type or mutant Parkin on oxidative damage, nitric oxide, antioxidant defenses, and the proteasome.
The Journal of biological chemistry 2002;277(32):28572-7.
2002: Urabe Takao; Tanaka Ryota; Noda Kazuyuki; Mizuno Yoshikuni
Anticoagulant therapy with a selective thrombin inhibitor for acute cerebral infarction: usefulness of coagulation markers for evaluation of efficacy.
Journal of thrombosis and thrombolysis 2002;13(3):155-60.
2002: Kobayashi Tomonori; Mori Hideo; Okuma Yasuyuki; Dickson Dennis W; Cookson Natalie; Tsuboi Yoshio; Motoi Yumiko; Tanaka Ryota; Miyashita Nobuo; Anno Midori; Narabayashi Hirotaro; Mizuno Yoshikuni
Contrasting genotypes of the tau gene in two phenotypically distinct patients with P301L mutation of frontotemporal dementia and parkinsonism linked to chromosome 17.
Journal of neurology 2002;249(6):669-75.
2002: Schlossmacher Michael G; Frosch Matthew P; Gai Wei Ping; Medina Miguel; Sharma Nutan; Forno Lysia; Ochiishi Tomoyo; Shimura Hideki; Sharon Ronit; Hattori Nobutaka; Langston J William; Mizuno Yoshikuni; Hyman Bradley T; Selkoe Dennis J; Kosik Kenneth S
Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies.
The American journal of pathology 2002;160(5):1655-67.
2002: Hattori Nobutaka; Mizuno Yoshikuni
[Mitochondrial dysfunction in Parkinson's disease]
Nippon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 4():406-11.
2002: Sato Kenichi; Hattori Nobutaka; Mizuno Yoshikuni
[Malignant migraine]
Nippon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 4():278-81.
2002: Aoki Yosuke; Saida Takahiko; Nakano Imaharu; Saito Toyokazu; Ikeguchi Kunihiko; Urabe Takao; Nishiguchi Etsuko; Suzuki Hideaki; Takahashi Kiyoshi; Mizuno Yoshikuni
[Determination of medullasin levels for the diagnosis of multiple sclerosis]
Rinsho byori. The Japanese journal of clinical pathology 2002;50(3):308-12.
2002: Tanaka Ryota; Mochizuki Hideki; Suzuki Asuka; Katsube Nobuo; Ishitani Ryoichi; Mizuno Yoshikuni; Urabe Takao
Induction of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) expression in rat brain after focal ischemia/reperfusion.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(3):280-8.
2002: Yokoyama Kazumasa; Ikebe Shin-ichiro; Komatsuzaki Yasuko; Takanashi Masafumi; Mori Hideo; Mochizuki Hideki; Mizuno Yoshikuni
[A 68-year-old woman with dementia and parkinsonism]
No to shinkei = Brain and nerve 2002;54(2):175-84.
2002: Okuma Yasuyuki; Mizuno Yoshikuni; Lee Robert G
Reciprocal Ia inhibition in patients with asymmetric spinal spasticity.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2002;113(2):292-7.
2002: Takanashi Masashi; Ohta Satoshi; Matsuoka Shuji; Mori Hideo; Mizuno Yoshikuni
Mixed multiple system atrophy and progressive supranuclear palsy: a clinical and pathological report of one case.
Acta neuropathologica 2002;103(1):82-7.
2001: Suzuki A; Mochizuki H; Kajiyama Y; Kimura M; Furukawa T; Ichikawa G; Arai H; Mizuno Y
[A case of convergence spasm in hysteria improved with a brief psychiatric assessment]
No to shinkei = Brain and nerve 2001;53(12):1141-4.
2001: Fukae J; Okuma Y; Noda K; Fujishima K; Goto K; Mizuno Y
[A quadriplegic patient with chronic inflammatory demyelinating polyneuropathy (CIDP) who responded well to corticosteroids and intravenous immunoglobulin therapy]
No to shinkei = Brain and nerve 2001;53(12):1115-8.
2001: Yamashiro K; Mori H; Suzuki A; Mori K; Hamano Y; Mizuno Y
[A patient with intravascular malignant lymphomatosis presenting subacute dementia one year after sustained urinary retention and high serum LDH activity from the onset]
Rinsho shinkeigaku = Clinical neurology 2001;41(11):784-91.
2001: Suzuki A; Ikebe S; Komatsuzaki Y; Takanashi M; Mori H; Hattori N; Mizuno Y
[A 64-year-old man with parkinsonism as an initial symptom followed by dementia associated with marked abnormal behaviours]
No to shinkei = Brain and nerve 2001;53(11):1075-87.
2001: Tanaka K; Suzuki T; Chiba T; Shimura H; Hattori N; Mizuno Y
Parkin is linked to the ubiquitin pathway.
Journal of molecular medicine (Berlin, Germany) 2001;79(9):482-94.
2001: Miwa H; Mizuno Y
Capgras syndrome in Parkinson's disease.
Journal of neurology 2001;248(9):804-5.
2001: Mochizuki H; Hayakawa H; Migita M; Shibata M; Tanaka R; Suzuki A; Shimo-Nakanishi Y; Urabe T; Yamada M; Tamayose K; Shimada T; Miura M; Mizuno Y
An AAV-derived Apaf-1 dominant negative inhibitor prevents MPTP toxicity as antiapoptotic gene therapy for Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(19):10918-23.
2001: Mori H; Motoi Y; Kobayashi T; Hasegawa M; Yamamura A; Iwatsubo T; Mizuno Y
Tau accumulation in a patient with pallidonigroluysian atrophy.
Neuroscience letters 2001;309(2):89-92.
2001: Mizuno Y; Hattori N; Mori H; Suzuki T; Tanaka K
Parkin and Parkinson's disease.
Current opinion in neurology 2001;14(4):477-82.
2001: Noda K; Okuma Y; Fukae J; Fujishima K; Goto K; Sadamasa H; Yoshiike T; Mizuno Y
Sweet's syndrome associated with encephalitis.
Journal of the neurological sciences 2001;188(1-2):95-7.
2001: Shimo-Nakanishi Y; Urabe T; Hattori N; Watanabe Y; Nagao T; Yokochi M; Hamamoto M; Mizuno Y
Polymorphism of the lipoprotein lipase gene and risk of atherothrombotic cerebral infarction in the Japanese.
Stroke; a journal of cerebral circulation 2001;32(7):1481-6.
2001: Kubo S I; Kitami T; Noda S; Shimura H; Uchiyama Y; Asakawa S; Minoshima S; Shimizu N; Mizuno Y; Hattori N
Parkin is associated with cellular vesicles.
Journal of neurochemistry 2001;78(1):42-54.
2001: Shimura H; Schlossmacher M G; Hattori N; Frosch M P; Trockenbacher A; Schneider R; Mizuno Y; Kosik K S; Selkoe D J
Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease.
Science (New York, N.Y.) 2001;293(5528):263-9.
2001: Tanaka R; Kobayashi T; Takanashi M; Tadokoro H; Mori H; Suda K; Kanazawa A; Mizuno Y
[A 68-year-old man with speech disturbance as the initial symptom followed by bradykinesia and dementia. Clinical conference]
No to shinkei = Brain and nerve 2001;53(6):585-97.
2001: Imai Y; Soda M; Inoue H; Hattori N; Mizuno Y; Takahashi R
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin.
Cell 2001;105(7):891-902.
2001: Sasaki Y; Takubo H; Arai T; Machida Y; Ikebe S; Yuki N; Mizuno Y
[Atypical Fisher syndrome with optic nerve involvement]
No to shinkei = Brain and nerve 2001;53(6):571-3.
2001: Wang M; Suzuki T; Kitada T; Asakawa S; Minoshima S; Shimizu N; Tanaka K; Mizuno Y; Hattori N
Developmental changes in the expression of parkin and UbcR7, a parkin-interacting and ubiquitin-conjugating enzyme, in rat brain.
Journal of neurochemistry 2001;77(6):1561-8.
2001: Jeon B S; Kim J M; Lee D S; Hattori N; Mizuno Y
An apparently sporadic case with parkin gene mutation in a Korean woman.
Archives of neurology 2001;58(6):988-9.
2001: Nisipeanu P; Inzelberg R; Abo Mouch S; Carasso R L; Blumen S C; Zhang J; Matsumine H; Hattori N; Mizuno Y
Parkin gene causing benign autosomal recessive juvenile parkinsonism.
Neurology 2001;56(11):1573-5.
2001: Shimo Y; Takanashi M; Ohta S; Terashima K; Mori H; Shirai T; Miwa H; Mizuno Y
[A-56-year-old woman with parkinsonism, whose mother had Parkinson's disease]
No to shinkei = Brain and nerve 2001;53(5):495-505.
2001: Kanazawa A; Mizuno Y; Narabayashi H
[Executive function in Parkinson's disease]
Rinsho shinkeigaku = Clinical neurology 2001;41(4-5):167-72.
2001: Furuya T; Miwa H; Hatano T; Miyashita N; Tanaka S; Mizuno Y
[Clinical features of myelitis in patients with atopic symptoms]
No to shinkei = Brain and nerve 2001;53(3):241-5.
2001: Okuma Y; Mizuno Y
Myoclonic tremor in patients with parkinsonian-type multiple system atrophy.
Movement disorders : official journal of the Movement Disorder Society 2001;16(2):378-9.
2001: Mogi M; Togari A; Kondo T; Mizuno Y; Kogure O; Kuno S; Ichinose H; Nagatsu T
Glial cell line-derived neurotrophic factor in the substantia nigra from control and parkinsonian brains.
Neuroscience letters 2001;300(3):179-81.
2001: Kanazawa A; Ikebe S; Komatsuzaki Y; Takanashi M; Mori H; Mochizuki H; Mizuno Y
[An 84-year-old woman with progressive mental deterioration and abnormal behavior]
No to shinkei = Brain and nerve 2001;53(2):199-209.
2001: Nohara C; Akiba H; Nakajima A; Inoue A; Koh C S; Ohshima H; Yagita H; Mizuno Y; Okumura K
Amelioration of experimental autoimmune encephalomyelitis with anti-OX40 ligand monoclonal antibody: a critical role for OX40 ligand in migration, but not development, of pathogenic T cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(3):2108-15.
2001: Lu C S; Wu J C; Tsai C H; Chen R S; Chou Y H; Hattori N; Yoshino H; Mizuno Y
Clinical and genetic studies on familial parkinsonism: the first report on a parkin gene mutation in a Taiwanese family.
Movement disorders : official journal of the Movement Disorder Society 2001;16(1):164-6.
2001: Mizuno Y; Hattori N; Kitada T; Matsumine H; Mori H; Shimura H; Kubo S; Kobayashi H; Asakawa S; Minoshima S; Shimizu N
Familial Parkinson's disease. Alpha-synuclein and parkin.
Advances in neurology 2001;86():13-21.
2001: Okuma Y; Fujishima K; Machida Y; Inagaki N; Sugita Y; Mizuno Y
Propriospinal negative myoclonus.
European neurology 2001;46(2):99-101.
2001: Miwa H; Furuya T; Tanaka S; Mizuno Y
Neurosarcoidosis associated with interferon therapy.
European neurology 2001;45(4):288-9.
2001: Okuma Y; Tanaka R; Fujishima K; Kobayashi T; Mizuno Y
Cortical reflex action myoclonus in neurosyphilis.
European neurology 2001;45(3):193-4.
2000: Hattori N; Shimura H; Kubo S; Suzuki T; Tanaka K; Mizuno Y
[Autosomal recessive juvenile parkinsonism: its pathogenesis is involved in the ubiquitin-proteasome pathway]
Rinsho shinkeigaku = Clinical neurology 2000;40(12):1293-6.
2000: Hatano T; Miwa H; Furuya T; Miyashita N; Tanaka S; Mizuno Y
[Anosognosia for hemiplegia in a patient with pontine infarction]
No to shinkei = Brain and nerve 2000;52(12):1117-20.
2000: Kubo S; Hattori T; Takanashi M; Mori H; Mizutani Y; Suda K; Hattori N; Mizuno Y
[A 57-year-old woman with progressive disturbance of gait and mental deterioration]
No to shinkei = Brain and nerve 2000;52(11):1035-44.
2000: Okuma Y; Urabe T; Mochizuki H; Miwa H; Shimo Y; Mori H; Mizuno Y
Asymmetric cortico-cortical inhibition in patients with progressive limb-kinetic apraxia.
Acta neurologica Scandinavica 2000;102(4):244-8.
2000: Ishiwata T; Suzuki A; Mochizuki H; Okuma Y; Mitani K; Mizuno Y
[Progressive limb-kinetic apraxia with myoclonus focal atrophy in the postcentral gyrus and the supplementary motor area]
No to shinkei = Brain and nerve 2000;52(10):925-8.
2000: Kitada T; Mizuno Y
[Molecular pathogenesis of familial Parkinson's disease]
Nippon rinsho. Japanese journal of clinical medicine 2000;58(10):2016-21.
2000: Tanaka R; Kobayashi T; Motoi Y; Anno M; Mizuno Y; Mori H
A case of frontotemporal dementia with tau P301L mutation in the Far East.
Journal of neurology 2000;247(9):705-7.
2000: Mizuno Y; Hattori N
[Progress in studies of Parkinson's disease]
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2000;89(9):1970-6.
2000: Hattori N; Shimura H; Kubo S; Kitada T; Wang M; Asakawa S; Minashima S; Shimizu N; Suzuki T; Tanaka K; Mizuno Y
Autosomal recessive juvenile parkinsonism: a key to understanding nigral degeneration in sporadic Parkinson's disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2000;20 Suppl():S85-90.
2000: Yamamura Y; Hattori N; Matsumine H; Kuzuhara S; Mizuno Y
Autosomal recessive early-onset parkinsonism with diurnal fluctuation: clinicopathologic characteristics and molecular genetic identification.
Brain & development 2000;22 Suppl 1():S87-91.
2000: Yamamoto T; Goto K; Suzuki A; Nakamura N; Mizuno Y
Long-term improvement of idiopathic hypertrophic cranial pachymeningitis by lymphocytapheresis.
Therapeutic apheresis : official journal of the International Society for Apheresis and the Japanese Society for Apheresis 2000;4(4):313-6.
2000: Sato K; Sato S; Ohta S; Mori H; Matsuoka S; Shirai T; Kanazaea A; Mizuno Y
[A 67-year-old man with progressive disturbance of gait]
No to shinkei = Brain and nerve 2000;52(7):643-53.
2000: Shimura H; Hattori N; Kubo S i; Mizuno Y; Asakawa S; Minoshima S; Shimizu N; Iwai K; Chiba T; Tanaka K; Suzuki T
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase.
Nature genetics 2000;25(3):302-5.
2000: Kitada T; Asakawa S; Minoshima S; Mizuno Y; Shimizu N
Molecular cloning, gene expression, and identification of a splicing variant of the mouse parkin gene.
Mammalian genome : official journal of the International Mammalian Genome Society 2000;11(6):417-21.
2000: Kitada T; Asakawa S; Matsumine H; Hattori N; Shimura H; Minoshima S; Shimizu N; Mizuno Y
Progress in the clinical and molecular genetics of familial parkinsonism.
Neurogenetics 2000;2(4):207-18.
2000: Sato T; Takahashi K; Okuma Y; Mizuno Y; Noto K; Katae M; Dambara T; Fukuchi Y
[A senile case of acute necrotizing myopathy presenting prolonged severe muscle paralysis due to high dose glucocorticoid and muscle relaxant]
Nippon Ronen Igakkai zasshi. Japanese journal of geriatrics 2000;37(3):250-4.
2000: Ikebe S; Mori H; Sumino S; Takanashi M; Hamano Y; Shirai T; Ohkuma Y; Mizuno Y
[A 77-year-old man with gait and gaze disturbance]
No to shinkei = Brain and nerve 2000;52(3):269-79.
2000: Iroi A; Miyashita N; Nakamura S; Ohizumi H; Mizuno Y
[A patient with marked immunodeficiency in an HTLV-I carrier: a case report]
Rinsho shinkeigaku = Clinical neurology 2000;40(2):135-9.
2000: Sasaki Y; Miwa H; Fukae J; Hatori K; Tanaka S; Mizuno Y
[Transient improvement in motor function and hemineglect by vestibular stimulation in a patient with right middle cerebral artery embolism]
No to shinkei = Brain and nerve 2000;52(1):49-52.
2000: Hattori N; Shimura H; Kubo S; Wang M; Shimizu N; Tanaka K; Mizuno Y
Importance of familial Parkinson's disease and parkinsonism to the understanding of nigral degeneration in sporadic Parkinson's disease.
Journal of neural transmission. Supplementum 2000;(60):101-16.
2000: Shimizu N; Asakawa S; Minoshima S; Kitada T; Hattori N; Matsumine H; Yokochi M; Yamamura Y; Mizuno Y
PARKIN as a pathogenic gene for autosomal recessive juvenile parkinsonism.
Journal of neural transmission. Supplementum 2000;(58):19-30.
2000: Urabe T; Yamasaki Y; Hattori N; Yoshikawa M; Uchida K; Mizuno Y
Accumulation of 4-hydroxynonenal-modified proteins in hippocampal CA1 pyramidal neurons precedes delayed neuronal damage in the gerbil brain.
Neuroscience 2000;100(2):241-50.
2000: Mogi M; Togari A; Kondo T; Mizuno Y; Komure O; Kuno S; Ichinose H; Nagatsu T
Caspase activities and tumor necrosis factor receptor R1 (p55) level are elevated in the substantia nigra from parkinsonian brain.
Journal of neural transmission (Vienna, Austria : 1996) 2000;107(3):335-41.
1999: Kitada T; Asakawa S; Matsumine H; Hattori N; Minoshima S; Shimizu N; Mizuno Y
Positional cloning of the autosomal recessive juvenile parkinsonism (AR-JP) gene and its diversity in deletion mutations.
Parkinsonism & related disorders 1999;5(4):163-8.
1999: Hattori N; Mizuno Y
[Parkin gene and its function; a key to understand nigral degeneration]
Rinsho shinkeigaku = Clinical neurology 1999;39(12):1259-61.
1999: Takanashi M; Urabe T; Ohta S; Hamano Y; Mori H; Shirai T; Kondo T; Mizuno Y
[A 73-year-old woman with familial Parkinson's disease]
No to shinkei = Brain and nerve 1999;51(12):1087-96.
1999: Iroi A; Miwa H; Iijima M; Fukae J; Hatori K; Tanaka S; Yano T; Mizuno Y
[The dissecting aortic aneurysm associated with polymyalgia rheumatica: a case report]
No to shinkei = Brain and nerve 1999;51(12):1051-4.
1999: Watanabe T; Miwa H; Wada K; Sugano K; Hatori K; Tanaka S; Mizuno Y
[Rhythmic involuntary movement of the neck in a patient with brainstem encephalitis]
No to shinkei = Brain and nerve 1999;51(12):1045-8.
1999: Okuma Y; Ohi K; Lee R G; Mizuno Y
Effects of test H-reflex size on reciprocal inhibition in forearm muscles.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 1999;110(12):2194-6.
1999: Shimura-Miura H; Hattori N; Kang D; Miyako K; Nakabeppu Y; Mizuno Y
Increased 8-oxo-dGTPase in the mitochondria of substantia nigral neurons in Parkinson's disease.
Annals of neurology 1999;46(6):920-4.
1999: Narabayashi H; Yamaguchi T; Sugi K; Mitamura H; Mizuno Y; Nakashima M
Safety study of lazabemide (Ro19-6327), a new MAO-B inhibitor, on cardiac arrhythmias and blood pressure of patients with Parkinson's disease.
Clinical neuropharmacology 1999;22(6):340-6.
1999: Agid Y; Ahlskog E; Albanese A; Calne D; Chase T; De Yebenes J; Factor S; Fahn S; Gershanik O; Goetz C; Koller W; Kurth M; Lang A; Lees A; Lewitt P; Marsden D; Melamed E; Michel P P; Mizuno Y; Obeso J; Oertel W; Olanow W; Poewe W; Pollak P; Tolosa E
Levodopa in the treatment of Parkinson's disease: a consensus meeting.
Movement disorders : official journal of the Movement Disorder Society 1999;14(6):911-3.
1999: Torizuka K; Mizuno Y; Kubo A; Konishi J; Yonekura Y; Hatazawa J; Momose T; Murata M; Amano T; Fukuyama H; Kuwabara Y
[Phase 2 clinical study of 123I-IBF, a dopamine D2 receptor imaging agent, to evaluate clinical efficacy and safety in Parkinson's disease and Parkinson syndromes]
Kaku igaku. The Japanese journal of nuclear medicine 1999;36(8):845-64.
1999: Miwa H; Sasaki Y; Hatori K; Tanaka S; Mizuno Y
[Idiopathic rabbit syndrome: a case report]
No to shinkei = Brain and nerve 1999;51(10):907-9.
1999: Nisipeanu P; Inzelberg R; Blumen S C; Carasso R L; Hattori N; Matsumine H; Mizuno Y
Autosomal-recessive juvenile parkinsonism in a Jewish Yemenite kindred: mutation of Parkin gene.
Neurology 1999;53(7):1602-4.
1999: Mogi M; Togari A; Kondo T; Mizuno Y; Komure O; Kuno S; Ichinose H; Nagatsu T
Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease.
Neuroscience letters 1999;270(1):45-8.
1999: Hattori N; Sumino S; Takanashi M; Mori H; Wakiya M; Shirai T; Sugita H; Mizuno Y
[An 80-year-old woman with parkinsonism and progressive dementia]
No to shinkei = Brain and nerve 1999;51(6):541-50.
1999: Hattori N; Mizuno Y
[The Parkin gene and its product in AR-JP]
No to shinkei = Brain and nerve 1999;51(6):493-500.
1999: Shimo-Nakanishi Y; Miwa H; Kobayashi H; Oshima H; Nakamura S; Urabe T; Mizuno Y
[Primary progressive limb-kinetic apraxia: a case report with an electrophysiological study]
No to shinkei = Brain and nerve 1999;51(5):439-43.
1999: Shimura H; Hattori N; Kubo S; Yoshikawa M; Kitada T; Matsumine H; Asakawa S; Minoshima S; Yamamura Y; Shimizu N; Mizuno Y
Immunohistochemical and subcellular localization of Parkin protein: absence of protein in autosomal recessive juvenile parkinsonism patients.
Annals of neurology 1999;45(5):668-72.
1999: Wang M; Hattori N; Matsumine H; Kobayashi T; Yoshino H; Morioka A; Kitada T; Asakawa S; Minoshima S; Shimizu N; Mizuno Y
Polymorphism in the parkin gene in sporadic Parkinson's disease.
Annals of neurology 1999;45(5):655-8.
1999: Sugano K; Goto K; Hatori K; Hattori T; Miwa H; Tanaka S; Mizuno Y
[Clinical and neuroradiological features of spontaneous intracranial hypotension: report of two cases]
No to shinkei = Brain and nerve 1999;51(4):345-8.
1999: Miwa H; Kondo T; Mizuno Y
[Striatonigral degeneration and sporadic olivopontocerebellar atrophy: a consideration of the clinical entity of multiple system atrophy]
No to shinkei = Brain and nerve 1999;51(4):305-12.
1999: Mizuno Y; Hattori N; Mori H
Genetics of Parkinson's disease.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 1999;53(3):109-16.
1999: Yoritaka A; Nakagawa-Hattori Y; Hattori N; Kitahara A; Mizuno Y
A large Japanese family with Machado-Joseph disease: clinical and genetic analysis.
Acta neurologica Scandinavica 1999;99(4):241-4.
1999: Hirsch E C; Hunot S; Faucheux B; Agid Y; Mizuno Y; Mochizuki H; Tatton W G; Tatton N; Olanow W C
Dopaminergic neurons degenerate by apoptosis in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 1999;14(2):383-5.
1999: Miwa H; Yoritaka A; Mizuno Y
Hemifacial spasm in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 1999;14(2):358-9.
1999: Hattori T; Tanaka S; Shimo Y; Anno M; Ohta S; Ishi K; Mori H; Ohkuma Y; Mizuno Y
[A 40-year-old woman with progressive dementia and abnormal behavior]
No to shinkei = Brain and nerve 1999;51(2):185-94.
1999: Kanazawa A; Noda K; Suzuki H; Ohta S; Mori H; Suda K; Takubo H; Mizuno Y
[A 96-year-old man with consciousness disturbance, convulsion, and left hemiplegia of acute onset]
No to shinkei = Brain and nerve 1999;51(1):83-93.
1999: Matsumine H; Saito M; Ishikawa A; Yokochi M; Yamamura Y; Tsuji S; Mizuno Y
Dopamine cell death by a single genetic mechanism: phenotypic analysis and linkage study of autosomal recessive juvenile parkinsonism.
Advances in neurology 1999;80():187-94.
1999: Mizuno Y; Shimoda-Matsubayashi S; Matsumine H; Morikawa N; Hattori N; Kondo T
Genetic and environmental factors in the pathogenesis of Parkinson's disease.
Advances in neurology 1999;80():171-9.
1998: Hattori N; Kitada T; Matsumine H; Asakawa S; Yamamura Y; Yoshino H; Kobayashi T; Yokochi M; Wang M; Yoritaka A; Kondo T; Kuzuhara S; Nakamura S; Shimizu N; Mizuno Y
Molecular genetic analysis of a novel Parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: evidence for variable homozygous deletions in the Parkin gene in affected individuals.
Annals of neurology 1998;44(6):935-41.
1998: Miyashita N; Kondo T; Wakiya M; Mori H; Shirai T; Takubo H; Mizuno Y
[A 61-year-old man with progressive gait disturbance, freezing, and vertical gaze paresis who developed esophagus cancer]
No to shinkei = Brain and nerve 1998;50(11):1041-52.
1998: Sugita Y; Matsumine H; Wakiya M; Mori H; Suda K; Kondo T; Mizuno Y
[A 64-year-old woman with progressive gait disturbance and dementia for one year]
No to shinkei = Brain and nerve 1998;50(9):861-70.
1998: Mizuno Y; Yoshino H; Ikebe S; Hattori N; Kobayashi T; Shimoda-Matsubayashi S; Matsumine H; Kondo T
Mitochondrial dysfunction in Parkinson's disease.
Annals of neurology 1998;44(3 Suppl 1):S99-109.
1998: Mori H; Kondo T; Yokochi M; Matsumine H; Nakagawa-Hattori Y; Miyake T; Suda K; Mizuno Y
Pathologic and biochemical studies of juvenile parkinsonism linked to chromosome 6q.
Neurology 1998;51(3):890-2.
1998: Mizuno Y; Hattori N; Matsumine H
Neurochemical and neurogenetic correlates of Parkinson's disease.
Journal of neurochemistry 1998;71(3):893-902.
1998: Yamamura Y; Kuzuhara S; Kondo K; Yanagi T; Uchida M; Matsumine H; Mizuno Y
Clinical, pathologic and genetic studies on autosomal recessive early-onset parkinsonism with diurnal fluctuation.
Parkinsonism & related disorders 1998;4(2):65-72.
1998: Hattori N; Matsumine H; Asakawa S; Kitada T; Yoshino H; Elibol B; Brookes A J; Yamamura Y; Kobayashi T; Wang M; Yoritaka A; Minoshima S; Shimizu N; Mizuno Y
Point mutations (Thr240Arg and Gln311Stop) [correction of Thr240Arg and Ala311Stop] in the Parkin gene.
Biochemical and biophysical research communications 1998;249(3):754-8.
1998: Mizuno Y
Second International Symposium on the Treatment of Parkinson's Disease.
Neurology 1998;51(2 Suppl 2):S1.
1998: Okuma Y; Hattori N; Nobukawa B; Mori H; Suda K; Takubo H; Mizuno Y
[A 74-year-old woman with parkinsonism and dementia who died four years after the onset]
No to shinkei = Brain and nerve 1998;50(7):671-82.
1998: Urabe T; Hattori N; Yoshikawa M; Yoshino H; Uchida K; Mizuno Y
Colocalization of Bcl-2 and 4-hydroxynonenal modified proteins in microglial cells and neurons of rat brain following transient focal ischemia.
Neuroscience letters 1998;247(2-3):159-62.
1998: Kondo T; Shimada H; Hatori K; Sugita Y; Mizuno Y
Talipexole protects dopaminergic neurons from methamphetamine toxicity in C57BL/6N mouse.
Neuroscience letters 1998;247(2-3):143-6.
1998: Takubo H; Hattori N; Irie S; Mizutani Y; Mori H; Suda K; Kondo T; Oshimi K; Mizuno Y
[A 45-year-old man with peripheral monocytosis and right hemiparesis]
No to shinkei = Brain and nerve 1998;50(5):481-9.
1998: Matsumine H; Yamamura Y; Kobayashi T; Nakamura S; Kuzuhara S; Mizuno Y
Early onset parkinsonism with diurnal fluctuation maps to a locus for juvenile parkinsonism.
Neurology 1998;50(5):1340-5.
1998: Shimo Y; Nohara C; Hotta M; Miwa H; Mizuno Y
[Superficial siderosis of the central nervous system: an electrophysiological study]
No to shinkei = Brain and nerve 1998;50(4):361-5.
1998: Matsumine H; Yamamura Y; Hattori N; Kobayashi T; Kitada T; Yoritaka A; Mizuno Y
A microdeletion of D6S305 in a family of autosomal recessive juvenile parkinsonism (PARK2).
Genomics 1998;49(1):143-6.
1998: Hattori N; Yoshino H; Tanaka M; Suzuki H; Mizuno Y
Genotype in the 24-kDa subunit gene (NDUFV2) of mitochondrial complex I and susceptibility to Parkinson disease.
Genomics 1998;49(1):52-8.
1998: Kitada T; Asakawa S; Hattori N; Matsumine H; Yamamura Y; Minoshima S; Yokochi M; Mizuno Y; Shimizu N
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism.
Nature 1998;392(6676):605-8.
1998: Sato S; Hattori N; Matsumine H; Imai H; Mizuno Y
[A patient with focal bi-parietal atrophy presenting motor clumsiness and cortical sensory loss]
Rinsho shinkeigaku = Clinical neurology 1998;38(3):246-51.
1998: Okuma Y; Shimo Y; Shimura H; Hatori K; Hattori T; Tanaka S; Kondo T; Mizuno Y
Familial cortical tremor with epilepsy: an under-recognized familial tremor.
Clinical neurology and neurosurgery 1998;100(1):75-8.
1998: Urabe T; Mori H; Sumino S; Miwa H; Wakiya M; Shirai T; Takubo H; Mizuno Y
[An 81-year-old woman with progressive motor disturbance, extrapyramidal features, dementia, and oculomotor palsy]
No to shinkei = Brain and nerve 1998;50(3):291-301.
1998: Mizuno Y; Mochizuki H; Sugita Y; Goto K
Apoptosis in neurodegenerative disorders.
Internal medicine (Tokyo, Japan) 1998;37(2):192-3.
1998: Miwa H; Koshimura I; Mizuno Y
Recurrent cranial neuropathy as a clinical presentation of idiopathic inflammation of the dura mater: a possible relationship to Tolosa-Hunt syndrome and cranial pachymeningitis.
Journal of the neurological sciences 1998;154(1):101-5.
1998: Motoi Y; Satoh K; Matsumine H; Wakiya M; Mori H; Shirai T; Kondo T; Mizuno Y
[A 49-year-old man with progressive bulbar palsy and respiratory failure]
No to shinkei = Brain and nerve 1998;50(1):93-100.
1998: Kobayashi T; Matsumine H; Matuda S; Mizuno Y
Association between the gene encoding the E2 subunit of the alpha-ketoglutarate dehydrogenase complex and Parkinson's disease.
Annals of neurology 1998;43(1):120-3.
1998: Morikawa N; Naoi M; Maruyama W; Ohta S; Kotake Y; Kawai H; Niwa T; Dostert P; Mizuno Y
Effects of various tetrahydroisoquinoline derivatives on mitochondrial respiration and the electron transfer complexes.
Journal of neural transmission (Vienna, Austria : 1996) 1998;105(6-7):677-88.
1998: Saito M; Matsumine H; Tanaka H; Ishikawa A; Shimoda-Matsubayashi S; Schäffer A A; Mizuno Y; Tsuji S
Refinement of the gene locus for autosomal recessive juvenile parkinsonism (AR-JP) on chromosome 6q25.2-27 and identification of markers exhibiting linkage disequilibrium.
Journal of human genetics 1998;43(1):22-31.
1997: Koshimura I; Sugita H; Sato K; Suzuki H; Mori H; Suda K; Takubo H; Mizuno Y
[A 62-year-old man with an acute onset of consciousness disturbances]
No to shinkei = Brain and nerve 1997;49(12):1161-70.
1997: Nohara C; Matsumine H; Suzuki K; Saito A; Ohtaka M; Mori H; Suda K; Kondo T; Hayakawa M; Kanai J; Mizuno Y
[(Neurological CPC-59). A 65-year-old man with a history of gastric cancer who presented progressive loss of vision, memory loss and consciousness disturbance]
No to shinkei = Brain and nerve 1997;49(11):1041-51.
1997: Shimoda-Matsubayashi S; Hattori T; Matsumine H; Shinohara A; Yoritaka A; Mori H; Kondo T; Chiba M; Mizuno Y
Mn SOD activity and protein in a patient with chromosome 6-linked autosomal recessive parkinsonism in comparison with Parkinson's disease and control.
Neurology 1997;49(5):1257-62.
1997: Motoi Y; Hattori Y; Miwa H; Shina K; Mizuno Y
[A case of post-hemiplegic painful dystonia following thalamic infarction with good response to botulinus toxin]
Rinsho shinkeigaku = Clinical neurology 1997;37(10):881-6.
1997: Koshimura I; Imai H; Hidano T; Endo K; Mochizuki H; Kondo T; Mizuno Y
Dimethoxyphenylethylamine and tetrahydropapaverine are toxic to the nigrostriatal system.
Brain research 1997;773(1-2):108-16.
1997: Kobayashi T; Takanashi M; Mori H; Suzuki M; Suda K; Takubo H; Mizuno Y
[A 85-year-old woman with one year history of convulsion, dementia, and consciousness disturbance]
No to shinkei = Brain and nerve 1997;49(10):953-61.
1997: Mizuno Y; Mochizuki H; Sugita Y; Goto K
[Nervous system diseases and apoptosis]
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 1997;86(9):1606-10.
1997: Miwa H; Mori H; Sumino S; Matsuoka S; Shirai T; Imai H; Mizuno Y
[Neurological CPC.57. An 80-year-old woman with four years history of muscle atrophy involving lower extremities predominantly on the right side]
No to shinkei = Brain and nerve 1997;49(9):857-65.
1997: Yoshino H; Hattori N; Urabe T; Uchida K; Tanaka M; Mizuno Y
Postischemic accumulation of lipid peroxidation products in the rat brain: immunohistochemical detection of 4-hydroxy-2-nonenal modified proteins.
Brain research 1997;767(1):81-6.
1997: Miyashita N; Imai H; Mori H; Kodera M; Shirai T; Mizuno Y
[A 76-year-old man with loss of vision and dementia]
No to shinkei = Brain and nerve 1997;49(8):773-82.
1997: Morikawa N; Mori H; Sumino S; Kodera M; Shirai T; Kondo T; Mizuno Y
[(Neurological CPC.55). A 60-year-old woman with progressive cerebellar ataxia, myoclonus, and dementia]
No to shinkei = Brain and nerve 1997;49(7):663-71.
1997: Satoh S; Miwa H; Nakano M; Kazumi Y; Mizuno Y
[Progressive loss of speech output with festinating speech--a case report]
No to shinkei = Brain and nerve 1997;49(7):646-9.
1997: Yamamoto M; Kondo I; Ogawa N; Asanuma M; Yamashita Y; Mizuno Y
Genetic association between susceptibility to Parkinson's disease and alpha1-antichymotrypsin polymorphism.
Brain research 1997;759(1):153-5.
1997: Ozawa T; Hayakawa M; Katsumata K; Yoneda M; Ikebe S; Mizuno Y
Fragile mitochondrial DNA: the missing link in the apoptotic neuronal cell death in Parkinson's disease.
Biochemical and biophysical research communications 1997;235(1):158-61.
1997: Mizuno Y; Kondo T
Mortality associated with selegiline in Parkinson's disease. What do the available data mean?
Drug safety : an international journal of medical toxicology and drug experience 1997;16(5):289-94.
1997: Ohkuma Y; Sato K; Ohtomo T; Ohishi H; Mitsuoka H; Mori H; Hirai S; Takubo H; Takeda N; Sato K; Mizuno Y
[A 29-year-old man with diabetes insipidus and cerebellar ataxia and development of spinal cord swelling 15 years after the onset]
No to shinkei = Brain and nerve 1997;49(5):473-81.
1997: Yoritaka A; Hattori N; Mori H; Kato K; Mizuno Y
An immunohistochemical study on manganese superoxide dismutase in Parkinson's disease.
Journal of the neurological sciences 1997;148(2):181-6.
1997: Okuma Y; Shimo Y; Hatori K; Hattori T; Tanaka S; Mizuno Y
Familial cortical tremor with epilepsy.
Parkinsonism & related disorders 1997;3(2):83-7.
1997: Goto K; Mochizuki H; Hattori T; Nakamura N; Mizuno Y
Neurotoxic effects of papaverine, tetrahydropapaverine and dimethoxyphenylethylamine on dopaminergic neurons in ventral mesencephalic-striatal co-culture.
Brain research 1997;754(1-2):260-8.
1997: Yoritaka A; Hattori T; Hattori Y; Mori H; Matsuoka S; Shirai T; Kondo T; Mizuno Y
[A 85-year-old woman with the onset of progressive gait disturbance at 80 years of the age]
No to shinkei = Brain and nerve 1997;49(4):379-89.
1997: Goto K; Sato K; Ienaga H; Mori H; Hirose Y; Shirai T; Takubo H; Danbara T; Mizuno Y
[A 36-year-old woman with acute onset left hemiplegia and anosognosia]
No to shinkei = Brain and nerve 1997;49(3):291-300.
1997: Matsumine H; Saito M; Shimoda-Matsubayashi S; Tanaka H; Ishikawa A; Nakagawa-Hattori Y; Yokochi M; Kobayashi T; Igarashi S; Takano H; Sanpei K; Koike R; Mori H; Kondo T; Mizutani Y; Schäffer A A; Yamamura Y; Nakamura S; Kuzuhara S; Tsuji S; Mizuno Y
Localization of a gene for an autosomal recessive form of juvenile Parkinsonism to chromosome 6q25.2-27.
American journal of human genetics 1997;60(3):588-96.
1997: Nakamura T; Yoritaka A; Sumino S; Suzuki H; Mori H; Suda K; Takubo H; Mizuno Y
[A 70-year-old man with a progressive gait disturbance and gaze palsy]
No to shinkei = Brain and nerve 1997;49(1):93-100.
1997: Kudo M; Mizuno Y; Morita H; Miyazaki M
[31P magnetic resonance spectroscopy(MRS) study in basal ganglia of patients with Parkinson's disease]
Nippon rinsho. Japanese journal of clinical medicine 1997;55(1):255-61.
1997: Hatori K; Kondo T; Mizuno Y
[Levodopa loading test as an early marker of Parkinson's disease]
Nippon rinsho. Japanese journal of clinical medicine 1997;55(1):207-12.
1997: Saito M; Matsumine H; Tanaka H; Ishikawa A; Matsubayashi S; Hattori Y; Mizuno Y; Tsuji S
[Clinical characteristics and linkage analysis of autosomal recessive form of juvenile parkinsonism(AR-JP)]
Nippon rinsho. Japanese journal of clinical medicine 1997;55(1):83-8.
1997: Mizuno Y
[Concept and diagnostic criteria of Parkinson's disease and parkinsonism]
Nippon rinsho. Japanese journal of clinical medicine 1997;55(1):16-20.
1997: Yoritaka A; Hattori N; Yoshino H; Mizuno Y
Catechol-O-methyltransferase genotype and susceptibility to Parkinson's disease in Japan. Short communication.
Journal of neural transmission (Vienna, Austria : 1996) 1997;104(11-12):1313-7.
1997: Ogawa N; Kanazawa I; Kowa H; Kuno S; Mizuno Y; Tashiro K; Yanagisawa N
Nationwide multicenter prospective study on the long-term effects of bromocriptine for Parkinson's disease. Final report of a ten-year follow-up.
European neurology 1997;38 Suppl 2():37-49.
1997: Mizuno Y; Yanagisawa N
Analyzer workshop on the treatment of Parkinson's disease.
European neurology 1997;38 Suppl 1():44-57.
1997: Kowa H; Kanazawa I; Goto I; Kuno S; Mizuno Y; Ogawa N; Tashiro K; Yanagisawa N
Nine-year follow-up study of bromocriptine monotherapy for Parkinson's disease.
European neurology 1997;38 Suppl 1():23-8.
1997: Yamamoto M; Yokochi M; Kuno S; Hattori Y; Tsukamoto Y; Narabayashi H; Tohgi H; Mizuno Y; Kowa H; Yanagisawa N; Kanazawa I
Effects of tolcapone, a catechol-O-methyltransferase inhibitor, on motor symptoms and pharmacokinetics of levodopa in patients with Parkinson's disease.
Journal of neural transmission (Vienna, Austria : 1996) 1997;104(2-3):229-36.
1997: Mochizuki H; Mori H; Mizuno Y
Apoptosis in neurodegenerative disorders.
Journal of neural transmission. Supplementum 1997;50():125-40.
1996: Mogi M; Harada M; Kondo T; Mizuno Y; Narabayashi H; Riederer P; Nagatsu T
The soluble form of Fas molecule is elevated in parkinsonian brain tissues.
Neuroscience letters 1996;220(3):195-8.
1996: Hattori Y; Motoi Y; Mori H; Takase S; Suda K; Imai H; Mizuno Y
[A 91-year-old man with a stroke, hypertension, and renal failure]
No to shinkei = Brain and nerve 1996;48(12):1155-64.
1996: Kondo T; Mizuno Y
[Free radical scavengers]
No to shinkei = Brain and nerve 1996;48(12):1099-113.
1996: Hattori N; Goto K; Mori H; Tominaga I; Kondo T; Mizuno Y
[A 46-year-old man with right-side dominant parkinsonism, who suffered a sudden death]
No to shinkei = Brain and nerve 1996;48(11):1059-67.
1996: Nakajima Y; Matsuda K; Mizuno Y
Akinesia and axial rigidity without limb rigidity: an intermediate form between progressive supranuclear palsy and pure akinesia of Imai and Narabayashi.
Parkinsonism & related disorders 1996;2(4):209-14.
1996: Sugita Y; Yokochi M; Ida A; Mori H; Shirai T; Imai H; Mizuno Y
[A 43-year-old woman with 18 years history of parkinsonism]
No to shinkei = Brain and nerve 1996;48(10):963-71.
1996: Nakamura N; Ohta S; Matsumoto M; Mori H; Takubo H; Mizuno Y
[A 63 year-old man with progressive gait disturbance and dysarthria]
No to shinkei = Brain and nerve 1996;48(9):865-75.
1996: Mogi M; Harada M; Kondo T; Mizuno Y; Narabayashi H; Riederer P; Nagatsu T
bcl-2 protein is increased in the brain from parkinsonian patients.
Neuroscience letters 1996;215(2):137-9.
1996: Nakamura N; Hattori N; Tanaka M; Mizuno Y
Specific detection of deleted mitochondrial DNA by in situ hybridization using a chimera probe.
Biochimica et biophysica acta 1996;1308(3):215-21.
1996: Shimoda-Matsubayashi S; Matsumine H; Kobayashi T; Nakagawa-Hattori Y; Shimizu Y; Mizuno Y
Structural dimorphism in the mitochondrial targeting sequence in the human manganese superoxide dismutase gene. A predictive evidence for conformational change to influence mitochondrial transport and a study of allelic association in Parkinson's disease.
Biochemical and biophysical research communications 1996;226(2):561-5.
1996: Mori H; Sato K; Hirasawa E; Kondo T; Mizuno Y
[A 22-year-old man with long-standing weakness and atrophy predominantly in the lower extremities]
No to shinkei = Brain and nerve 1996;48(8):763-71.
1996: Hatori K; Kondo T; Mizuno Y
Levodopa absorption profile in Parkinson's disease: Evidence to indicate qualitative difference from the control.
Parkinsonism & related disorders 1996;2(3):137-44.
1996: Yamamoto T; Kitada T; Hirasawa E; Mori H; Mizuno Y
[A 34-year-old woman with delayed motor milestones, high arched palate, and proximal muscle weakness]
No to shinkei = Brain and nerve 1996;48(7):677-84.
1996: Urabe T; Hattori N; Nagamatsu S; Sawa H; Mizuno Y
Expression of glucose transporters in rat brain following transient focal ischemic injury.
Journal of neurochemistry 1996;67(1):265-71.
1996: Goto K; Mochizuki H; Imai H; Akiyama H; Mizuno Y
An immuno-histochemical study of ferritin in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced hemiparkinsonian monkeys.
Brain research 1996;724(1):125-8.
1996: Takubo H; Kondo T; Mori H; Miyake T; Suda K; Yokochi M; Imai H; Mizuno Y
[A 62-year-old man with familial parkinsonism with the onset at 24 years of the age]
No to shinkei = Brain and nerve 1996;48(6):587-97.
1996: Mochizuki H; Goto K; Mori H; Mizuno Y
Histochemical detection of apoptosis in Parkinson's disease.
Journal of the neurological sciences 1996;137(2):120-3.
1996: Miwa H; Yamaji Y; Abe H; Mizuno Y
Evaluation of the somatosensory evoked blink response in patients with neurological disorders.
Journal of neurology, neurosurgery, and psychiatry 1996;60(5):539-43.
1996: Mori H; Oda M; Mizuno Y
Cortical ballooned neurons in progressive supranuclear palsy.
Neuroscience letters 1996;209(2):109-12.
1996: Miyasaka H; Mori H; Saikawa T; Shirai T; Kondo T; Imai H; Mizuno Y
[A 78-year-old man with young onset parkinsonism and sudden death]
No to shinkei = Brain and nerve 1996;48(5):487-95.
1996: Mizuno Y; Kondo T; Takubo H; Yokochi F
[A long-term clinical effect of selegiline hydrochloride on Parkinson's disease]
No to shinkei = Brain and nerve 1996;48(5):467-72.
1996: Furukawa Y; Shimadzu M; Rajput A H; Shimizu Y; Tagawa T; Mori H; Yokochi M; Narabayashi H; Hornykiewicz O; Mizuno Y; Kish S J
GTP-cyclohydrolase I gene mutations in hereditary progressive amd dopa-responsive dystonia.
Annals of neurology 1996;39(5):609-17.
1996: Mizuno Y; Yokochi F; Ohta S; Mori H; Takubo H
[A 65-year-old man with Parkinsonism, gaze palsy, and dementia]
No to shinkei = Brain and nerve 1996;48(4):381-93.
1996: Yoritaka A; Hattori N; Uchida K; Tanaka M; Stadtman E R; Mizuno Y
Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):2696-701.
1996: Okuma Y; Tanaka S; Nomura Y; Mori H; Yan H; Shirai T; Kondo T; Segawa M; Mizuno Y
[A 63-year-old woman with muscle weakness, myotonia, and parkinsonism]
No to shinkei = Brain and nerve 1996;48(3):287-97.
1996: Miwa H; Mori H; Abe K; Hoshino I; Mizuno Y
[Corticobasal degeneration and progressive supranuclear palsy--differentiation by somatosensory-evoked potentials]
No to shinkei = Brain and nerve 1996;48(3):253-7.
1996: Morikawa N; Nakagawa-Hattori Y; Mizuno Y
Effect of dopamine, dimethoxyphenylethylamine, papaverine, and related compounds on mitochondrial respiration and complex I activity.
Journal of neurochemistry 1996;66(3):1174-81.
1996: Matsubayashi S; Sato K; Takase M; Mori H; Suda K; Kondo T; Mizuno Y
[A 83 year-old woman with dementia, gait disturbance, and convulsion]
No to shinkei = Brain and nerve 1996;49(2):185-93.
1996: Hattori T; Kitada T; Suzuki H; Imai H; Mizuno Y
[A 56-year-old man with fever, backache and tetraparesis]
No to shinkei = Brain and nerve 1996;48(2):183-93.
1996: Miwa H; Mizuno Y
[Dystonia preceding dopa-responsive parkinsonism--heterogeneous clinical features]
No to shinkei = Brain and nerve 1996;48(2):149-54.
1996: Koshimura I; Takeda N; Ohtomo T; Shimada J; Sugano K; Mori H; Mizuno Y; Sato K
[A 32-year-old man who developed a posterior fossa mass 12 years after the radiation therapy for cerebellar arteriovenous malformation]
No to shinkei = Brain and nerve 1996;48(1):81-9.
1996: Mizuno Y; Ikebe S; Mochizuki H; Matumine H; Kondo T
[Etiology and pathogenesis of parkinson's disease]
No to shinkei = Brain and nerve 1996;48(1):5-17.
1996: Kojima J; Yoritaka A; Ikebe S; Nakajima Y; Mizuno Y
[The relationship between visual agnosia and visual pathway for perception]
No to shinkei = Brain and nerve 1996;48(1):31-7.
1996: Miwa H; Hatori K; Kondo T; Imai H; Mizuno Y
Thalamic tremor: case reports and implications of the tremor-generating mechanism.
Neurology 1996;46(1):75-9.
1996: Takakubo F; Yamamoto M; Ogawa N; Yamashita Y; Mizuno Y; Kondo I
Genetic association between cytochrome P450IA1 gene and susceptibility to Parkinson's disease.
Journal of neural transmission (Vienna, Austria : 1996) 1996;103(7):843-9.
1996: Tashiro K; Goto I; Kanazawa I; Kowa H; Kuno S; Mizuno Y; Ogawa N; Yanagisawa N
Eight-year follow-up study of bromocriptine monotherapy for Parkinson's disease.
European neurology 1996;36 Suppl 1():32-7.
1996: Furukawa Y; Mizuno Y; Narabayashi H
Early-onset parkinsonism with dystonia. Clinical and biochemical differences from hereditary progressive dystonia or DOPA-responsive dystonia.
Advances in neurology 1996;69():327-37.
1995: Nakagawa-Hattori Y; Hattori T; Kondo T; Mizuno Y
S-methylation in Parkinson's disease.
Neurology 1995;45(12):2279-81.
1995: Morimoto Y; Murayama N; Kuwano A; Kondo I; Yamashita Y; Mizuno Y
Association analysis of a polymorphism of the monoamine oxidase B gene with Parkinson's disease in a Japanese population.
American journal of medical genetics 1995;60(6):570-2.
1995: Nagaoka M; Nakamura N; Yamamura A; Mori H; Shirai T; Mizuno Y
[A 75-year-old man with parkinsonism and sudden death]
No to shinkei = Brain and nerve 1995;47(12):1199-208.
1995: Matsumine H; Shimizu T; Sato K; Mizuno Y
[Anosognosia, 2)anosodiaphoria]
No to shinkei = Brain and nerve 1995;47(12):1196-7.
1995: Mizuno Y; Mori H; Kondo T
Parkinson's disease: from etiology to treatment.
Internal medicine (Tokyo, Japan) 1995;34(11):1045-54.
1995: Hattori N; Suzuki H; Wang Y; Minoshima S; Shimizu N; Yoshino H; Kurashima R; Tanaka M; Ozawa T; Mizuno Y
Structural organization and chromosomal localization of the human nuclear gene (NDUFV2) for the 24-kDa iron-sulfur subunit of complex I in mitochondrial respiratory chain.
Biochemical and biophysical research communications 1995;216(3):771-7.
1995: Hattori N; Sugano K; Wakiya M; Mori H; Shirai T; Mizuno Y
[A 56-year-old woman with parkinsonism and dementia with the age of onset at 41 years]
No to shinkei = Brain and nerve 1995;47(9):911-9.
1995: Hirabayashi K; Morikawa N; Mori H; Miyake T; Suda K; Kondo T; Mizuno Y
[A 86-year-old woman with dementia, gait and speech disturbance, and right hemiparesis]
No to shinkei = Brain and nerve 1995;47(8):803-12.
1995: Takubo H; Satoh S; Mori H; Tsukahara M; Suda K; Imai H; Mizuno Y
[A 57-year-old woman with gait disturbance, headache, character change, convulsion, and coma]
No to shinkei = Brain and nerve 1995;47(7):699-708.
1995: Kondo T; Mochizuki H; Ueda G; Mori H; Shirai T; Imai H; Mizuno Y
[A 51-year-old man with early onset parkinsonism]
No to shinkei = Brain and nerve 1995;47(6):603-12.
1995: Imamura N; Miwa H; Hironishi M; Goto K; Mizuno Y
[A characteristic blink response observed in a patient with Lance-Adams syndrome--somatosensory-evoked blink response]
No to shinkei = Brain and nerve 1995;47(6):581-4.
1995: Hattori Y; Nohara C; Hirasawa E; Mori H; Imai H; Mizuno Y
[A 21-year-old man with distal dominant progressive muscle atrophy]
No to shinkei = Brain and nerve 1995;47(5):509-18.
1995: Mizuno Y; Ikebe S; Hattori N; Nakagawa-Hattori Y; Mochizuki H; Tanaka M; Ozawa T
Role of mitochondria in the etiology and pathogenesis of Parkinson's disease.
Biochimica et biophysica acta 1995;1271(1):265-74.
1995: Imai H; Furukawa Y; Sumino S; Mori H; Ueda G; Shirai T; Kondo T; Mizuno Y
[A 65-year-old woman with dysarthria, dysphagia, weakness, and gait disturbance]
No to shinkei = Brain and nerve 1995;47(4):399-410.
1995: Mizuno Y; Kondo T; Narabayashi H
Pergolide in the treatment of Parkinson's disease.
Neurology 1995;45(3 Suppl 3):S13-21.
1995: Nakajima Y; Hattori T; Mizuno Y
[Absence of P300 in patients with bilateral hippocampal lesions caused by herpes simplex encephalitis]
No to shinkei = Brain and nerve 1995;47(3):270-5.
1995: Furukawa Y; Nishi K; Mizuno Y; Narabayashi H
[Significance of CSF biopterin and neopterin in hereditary progressive dystonia with marked diurnal fluctuation (HPD)--a clue to pathogenesis]
No to shinkei = Brain and nerve 1995;47(3):261-8.
1995: Mochizuki H; Satoh S; Saikawa M; Mori H; Shirai T; Kondo T; Mizuno Y
[A 74-year-old man with urinary incontinence, right leg weakness and multiple cranial nerve palsies]
No to shinkei = Brain and nerve 1995;47(2):199-209.
1995: Miwa H; Imamura N; Kogahara K; Ohori T; Mizuno Y
Somatosensory evoked blink response: findings in patients with Miller Fisher syndrome and in normal subjects.
Journal of neurology, neurosurgery, and psychiatry 1995;58(1):95-9.
1995: Furukawa Y; Mizuno Y; Nishi K; Narabayashi H
A clue to the pathogenesis of dopa-responsive dystonia.
Annals of neurology 1995;37(1):139-40.
1995: Anno M; Gotoh K; Hirasawa E; Mori H; Nakajima Y; Mizuno Y
[A 54-year-old man with progressive proximal muscle atrophy and gynecomastia]
No to shinkei = Brain and nerve 1995;47(1):87-96.
1994: Komiya T; Kudo M; Urabe T; Mizuno Y
Compliance with antiplatelet therapy in patients with ischemic cerebrovascular disease. Assessment by platelet aggregation testing.
Stroke; a journal of cerebral circulation 1994;25(12):2337-42.
1994: Miyasaka H; Nohara C; Ohtani H; Suda K; Mori H; Nakajima Y; Mizuno Y
[A 65-year-old woman with headache, facial pain, and progressive multiple cranial neuropathy]
No to shinkei = Brain and nerve 1994;46(11):1101-11.
1994: Hatori K; Morikawa N; Nitta T; Mori H; Satoh K; Mizuno Y
[A 37-year-old man with memory loss, homonymous hemianopsia, and elevation of anti-herpes simplex virus antibody titer]
No to shinkei = Brain and nerve 1994;46(10):1001-9.
1994: Mizuno Y; Ikebe S; Hattori N; Mochizuki H; Nakagawa-Hattori Y; Kondo T
Studies on the pathogenesis of Parkinson's disease in Japan.
Archives of gerontology and geriatrics 1994;19(2):105-21.
1994: Komiya T; Shike T; Mori H; Santo M L; Suda K; Kondo T; Mizuno Y
[A 54-year-old man with generalized muscle atrophy and oculomotor paresis]
No to shinkei = Brain and nerve 1994;46(9):895-904.
1994: Nakajima Y; Sekiya M; Goto K; Miyasaka H; Mizuno Y
[Characteristic event-related potentials evoked by somatosensory tasks in a patient with right-left disorientation and finger agnosia]
No to shinkei = Brain and nerve 1994;46(9):873-8.
1994: Hattori Y; Goto Y; Sakuta R; Nonaka I; Mizuno Y; Horai S
Point mutations in mitochondrial tRNA genes: sequence analysis of chronic progressive external ophthalmoplegia (CPEO)
Journal of the neurological sciences 1994;125(1):50-5.
1994: Mizuno Y; Kondo T; Mori H
Various aspects of motor fluctuations and their management in Parkinson's disease.
Neurology 1994;44(7 Suppl 6):S29-34.
1994: Kondo T; Nakamura N; Iesaki T; Kono A; Oomuro H; Mori H; Shirai T; Yamaguchi H; Mizuno Y
[A 46-year-old man with cardiac failure and statues epileptics]
No to shinkei = Brain and nerve 1994;46(7):691-701.
1994: Furukawa Y; Nakajima Y; Nakagawa M; Matsumoto M; Mori H; Mizuno Y
[A 75-year-old woman with multiple cranial nerve palsies and a paranasal mass]
No to shinkei = Brain and nerve 1994;46(6):593-600.
1994: Hatta S; Mochizuki H; Kuru Y; Miwa H; Kondo T; Mori H; Mizuno Y
Serial neuroradiological studies in focal cerebritis.
Neuroradiology 1994;36(4):285-8.
1994: Matsumine H; Matsubayashi S; Nitta T; Matsumoto T; Mori H; Yamamoto T; Sato K; Mizuno Y
[A 52-year-old man with sensory aphasia and multiple intracranial masses]
No to shinkei = Brain and nerve 1994;46(5):499-506.
1994: Mizuno Y; Kondo T; Takubo H; Yokochi F
[A long-term clinical effect of selegiline hydrochloride on Parkinson's disease]
No to shinkei = Brain and nerve 1994;46(5):465-71.
1994: Mizuno Y; Nakajima Y
[The 3 major symptoms and their physiopathology in Parkinson disease]
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 1994;83(4):544-8.
1994: Imai H; Matsubayashi S; Santo M L; Mori H; Suda K; Kondo T; Mizuno Y
[A 85-year-old right-handed woman with aphasia and left hemiparesis]
No to shinkei = Brain and nerve 1994;46(4):397-405.
1994: Nakamura N; Furukawa Y; Fujiki K; Hayakawa M; Mizuno Y
[Leber's hereditary optic neuropathy with onset at the age of 54 years]
Rinsho shinkeigaku = Clinical neurology 1994;34(3):258-60.
1994: Hironishi M; Koshimura I; Nishi K; Komiya T; Mizuno Y
[Pretectal syndrome caused by a plaque of multiple sclerosis]
Rinsho shinkeigaku = Clinical neurology 1994;34(3):236-40.
1994: Matsuda K; Hatori K; Ohtani H; Mori H; Suda K; Imai H; Mizuno Y
[A 78-year-old man with progressive gait disturbance, dysphagia, and dementia]
No to shinkei = Brain and nerve 1994;46(3):297-305.
1994: Yokota J; Imai H; Mizuno Y; Hishii M; Ito M
[Unilateral supranuclear abducens palsy in a pineal tumor]
No to shinkei = Brain and nerve 1994;46(3):291-5.
1994: Mochizuki H; Nakamura N; Nishi K; Mizuno Y
Apoptosis is induced by 1-methyl-4-phenylpyridinium ion (MPP+) in ventral mesencephalic-striatal co-culture in rat.
Neuroscience letters 1994;170(1):191-4.
1994: Mizuno Y
[Parkinson's disease]
No to shinkei = Brain and nerve 1994;46(3):217-27.
1994: Mizuno Y; Matuda S; Yoshino H; Mori H; Hattori N; Ikebe S
An immunohistochemical study on alpha-ketoglutarate dehydrogenase complex in Parkinson's disease.
Annals of neurology 1994;35(2):204-10.
1994: Mochizuki H; Imai H; Endo K; Yokomizo K; Murata Y; Hattori N; Mizuno Y
Iron accumulation in the substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced hemiparkinsonian monkeys.
Neuroscience letters 1994;168(1-2):251-3.
1994: Tanabe K; Yokochi F; Hirai S; Mori H; Suda K; Kondo T; Mizuno Y
[A 75-year-old man with parkinsonism and delirium]
No to shinkei = Brain and nerve 1994;46(1):85-92.
1994: Yanagisawa N; Kanazawa I; Goto I; Kowa H; Kuno S; Mizuno Y; Tashiro K; Ogawa N
Seven-year follow-up study of bromocriptine therapy for Parkinson's disease.
European neurology 1994;34 Suppl 3():29-35.
1993: Mizuno Y
[Diagnostic criteria for brain death]
Rinsho shinkeigaku = Clinical neurology 1993;33(12):1318-20.
1993: Yokochi M; Takaoka S; Kawano H; Mori H; Shirai T; Imai H; Mizuno Y
[A 77-year-old woman with myoclonus and epilepsy]
No to shinkei = Brain and nerve 1993;45(12):1173-85.
1993: Ishigaki Y; Hironishi M; Toganou T; Matsumoto T; Ohta S; Suda K; Nishi K; Yamaguchi H; Mizuno Y
[A 79-year-old man with rapidly progressive tetraparesis]
No to shinkei = Brain and nerve 1993;45(11):1081-9.
1993: Ikebe S; Yokochi F; Wada T; Arakawa A; Mori H; Suda K; Kondo T; Mizuno Y
[A 66-year-old man with backache and progressive difficulty of gait]
No to shinkei = Brain and nerve 1993;45(10):981-90.
1993: Tanaka S; Kitada T; Kanazawa A; Ueda G; Noguchi K; Mori H; Kondo T; Shirai T; Mizuno Y
[A 62-year-old man with multiple cranial nerve palsies on the right side and a pelvic mass]
No to shinkei = Brain and nerve 1993;45(8):777-87.
1993: Mizuno Y; Tanaka S; Mori H; Kondo T
[A 61-year-old man with rapidly progressing dementia and gait disturbance]
No to shinkei = Brain and nerve 1993;45(7):679-85.
1993: Ohkuma Y; Hatta S; Kubota M; Kohno H; Mizutani Y; Shirai T; Sato T; Imai H; Koide H; Mizuno Y
[A 70-year-old man with right hemiparesis and mutism]
No to shinkei = Brain and nerve 1993;45(6):579-84.
1993: Suzuki H; Kawai S; Okada R; Hayashi Y; Kanazawa A; Mizuno Y; Obata K; Shiotsu H; Kuwabara N
[Autopsy results of an elderly case of Parkinson's disease and aorto-esophageal fistula who died of a massive hematemesis during prolonged bed rest]
Nippon Ronen Igakkai zasshi. Japanese journal of geriatrics 1993;30(5):387-92.
1993: Nakajima Y; Kitada T; Mizutani Y; Yamamoto Y; Kuwabara N; Sato T; Kondo T; Mizuno Y
[A 50-year-old man with metamorphopsia and optic nerve swelling]
No to shinkei = Brain and nerve 1993;45(5):485-92.
1993: Nishi K; Kitada T; Mori H; Wada T; Kuwabara N; Imai H; Sato T; Mizuno Y
[A 81-year-old man with dementia, gait disturbance, hemiparesis, and sympathetic apraxia]
No to shinkei = Brain and nerve 1993;45(4):389-95.
1993: Miwa H; Imamura N; Mizutani Y; Shiotsu H; Kuwabara N; Nagaoka M; Sato T; Mizuno Y
[A 93-year-old woman presenting consciousness disturbance, left hemiplegia, and respiratory distress]
No to shinkei = Brain and nerve 1993;45(3):281-7.
1993: Mizuno Y
[Clinical subtypes of Parkinson's disease]
No to shinkei = Brain and nerve 1993;45(2):105-12.
1993: Yamamoto T; Gotoh K; Sato T; Shiotsu H; Kuwabara N; Nagaoka M; Mizuno Y
[Forty-six-year-old woman with progressive external ophthalmoplegia and limb weakness]
No to shinkei = Brain and nerve 1993;45(1):85-92.
1993: Furukawa Y; Nishi K; Kondo T; Mizuno Y; Narabayashi H
CSF biopterin levels and clinical features of patients with juvenile parkinsonism.
Advances in neurology 1993;60():562-7.
1993: Mizuno Y; Ikebe S; Hattori N; Kondo T; Tanaka M; Ozawa T
Mitochondrial energy crisis in Parkinson's disease.
Advances in neurology 1993;60():282-7.
1993: Hattori N; Ikebe S; Tanaka M; Ozawa T; Mizuno Y
Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in Parkinson's disease.
Advances in neurology 1993;60():292-6.
1992: Mizuno Y
[Japanese clinical statistical data of patients with parkinson's disease]
Nippon rinsho. Japanese journal of clinical medicine 1992;50 Suppl():109-17.
1992: Furukawa Y; Nishi K; Kondo T; Tanabe K; Mizuno Y
Significance of CSF total neopterin and biopterin in inflammatory neurological diseases.
Journal of the neurological sciences 1992;111(1):65-72.
1992: Yoritaka A; Kogahara K; Yoshino H; Imai H; Mizuno Y
[Clinical and neuroradiological studies on orbital myositis and Tolosa-Hunt syndrome]
Rinsho shinkeigaku = Clinical neurology 1992;32(6):593-9.
1992: Furukawa Y; Nishi K; Kondo T; Mizuno Y; Narabayashi H
Juvenile parkinsonism: ventricular CSF biopterin levels and clinical features.
Journal of the neurological sciences 1992;108(2):207-13.
1992: Nakagawa-Hattori Y; Yoshino H; Kondo T; Mizuno Y; Horai S
Is Parkinson's disease a mitochondrial disorder?
Journal of the neurological sciences 1992;107(1):29-33.
1992: Miwa H; Hirasawa M; Yoshino H; Hayashi Y; Mizuno Y
[The early hemiparesis of stroke in evolution of basilar artery--case report]
No to shinkei = Brain and nerve 1992;44(1):49-52.
1992: Yokota J; Imai H; Seki K; Ninomiya C; Mizuno Y
Orthostatic tremor associated with voice tremor.
European neurology 1992;32(6):354-8.
1992: Nakanishi T; Iwata M; Goto I; Kanazawa I; Kowa H; Mannen T; Mizuno Y; Nishitani H; Ogawa N; Takahashi A
Nation-wide collaborative study on the long-term effects of bromocriptine in the treatment of parkinsonian patients. Final report.
European neurology 1992;32 Suppl 1():9-22.
1992: Nakanishi T; Kanazawa I; Iwata M; Goto I; Kowa H; Mannen T; Mizuno Y; Nishitani H; Ogawa N; Takahashi A
Nation-wide collaborative study on the long-term effects of bromocriptine in the treatment of parkinsonian patients: analysis on the maintenance and the change of the original mode of treatment.
European neurology 1992;32 Suppl 1():23-9.
1992: Mizuno Y
Drug therapy of Parkinson's disease. An overview.
European neurology 1992;32 Suppl 1():3-8.
1992: Yoshino H; Nakagawa-Hattori Y; Kondo T; Mizuno Y
Mitochondrial complex I and II activities of lymphocytes and platelets in Parkinson's disease.
Journal of neural transmission. Parkinson's disease and dementia section 1992;4(1):27-34.
1991: Mannen T; Mizuno Y; Iwata M; Goto I; Kanazawa I; Kowa H; Nishitani H; Ogawa N; Takahashi A; Tashiro K
A multi-center, double-blind study on slow-release bromocriptine in the treatment of Parkinson's disease.
Neurology 1991;41(10):1598-602.
1991: Hirasawa M; Nakano M; Shiohama N; Komiya T; Mizuno Y
[Amnestic syndrome with bilateral lesions restricted to the field CA-1 of both hippocampi--a case report with CT and MRI findings]
Rinsho shinkeigaku = Clinical neurology 1991;31(10):1147-50.
1991: Hatori K; Urabe T; Kanazawa A; Mizuno Y
[A case of brainstem vascular malformation with isolated trochlear nerve palsy as the initial symptom]
No to shinkei = Brain and nerve 1991;43(10):965-8.
1991: Hattori N; Tanaka M; Ozawa T; Mizuno Y
Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in Parkinson's disease.
Annals of neurology 1991;30(4):563-71.
1991: Mizuno Y
[Parkinson's disease; etiology and animal model]
No to shinkei = Brain and nerve 1991;43(8):703-11.
1991: Takahashi K; Mochizuki H; Yoshino H; Imai H; Mizuno Y
[Post-hemiplegic dystonia with a discrete lesion in the postero-lateral part of the contralateral putamen]
Rinsho shinkeigaku = Clinical neurology 1991;31(6):662-5.
1991: Nakanishi T; Mizuno Y; Goto I; Iwata M; Kanazawa I; Kowa H; Mannen T; Nishitani H; Ogawa N; Takahashi A
A nationwide collaborative study on the long-term effects of bromocriptine in patients with Parkinson's disease. The fourth interim report.
European neurology 1991;31 Suppl 1():3-16.
1990: Ozawa T; Tanaka M; Ikebe S; Ohno K; Kondo T; Mizuno Y
Quantitative determination of deleted mitochondrial DNA relative to normal DNA in parkinsonian striatum by a kinetic PCR analysis.
Biochemical and biophysical research communications 1990;172(2):483-9.
1990: Abe K; Ohta S; Komiya T; Sakamoto N; Mizuno Y
Fibromuscular dysplasia complicated by primary thrombocythemia presenting recurrent ischemic cerebrovascular accidents: a case report.
Japanese journal of medicine 1990;29(5):548-54.
1990: Ikebe S; Tanaka M; Ohno K; Sato W; Hattori K; Kondo T; Mizuno Y; Ozawa T
Increase of deleted mitochondrial DNA in the striatum in Parkinson's disease and senescence.
Biochemical and biophysical research communications 1990;170(3):1044-8.
1990: Suzuki K; Mizuno Y; Yoshida M
Inhibition of mitochondrial respiration by 1,2,3,4-tetrahydroisoquinoline-like endogenous alkaloids in mouse brain.
Neurochemical research 1990;15(7):705-10.
1990: Mizuno Y; Suzuki K; Ohta S
Postmortem changes in mitochondrial respiratory enzymes in brain and a preliminary observation in Parkinson's disease.
Journal of the neurological sciences 1990;96(1):49-57.
1990: Shioya N; Yokota J; Miwa H; Hattori T; Mizuno Y
[Vestibular ataxia caused by meningeal carcinomatosis]
Rinsho shinkeigaku = Clinical neurology 1990;30(3):308-13.
1990: Mizuno Y
[The role of oxygen free radicals in the aging of the brain]
Nippon Ronen Igakkai zasshi. Japanese journal of geriatrics 1990;27(2):182-7.
1990: Nakanishi T; Kanazawa I; Goto I; Iwata M; Kowa H; Mannen T; Mizuno Y; Nishitani H; Ogawa N; Takahashi A
Third interim report of the nationwide collaborative study on the long-term effects of bromocriptine in the treatment of parkinsonian patients.
European neurology 1990;30 Suppl 1():3-8.
1990: Shimoda-Matsubayashi S; Kuru Y; Sumie H; Ito T; Hattori N; Okuma Y; Mizuno Y
MRI findings in the mild type of mucopolysaccharidosis II (Hunter's syndrome).
Neuroradiology 1990;32(4):328-30.
1989: Mizuno Y
[Contribution of MPTP to studies on the pathogenesis of Parkinson's disease]
Rinsho shinkeigaku = Clinical neurology 1989;29(12):1494-6.
1989: Mizuno Y; Ohta S; Tanaka M; Takamiya S; Suzuki K; Sato T; Oya H; Ozawa T; Kagawa Y
Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease.
Biochemical and biophysical research communications 1989;163(3):1450-5.
1989: Nakanishi T; Iwata M; Goto I; Kanazawa I; Kowa H; Mannen T; Mizuno Y; Nishitani H; Ogawa N; Takahashi A
Second interim report of the nation-wide collaborative study on the long-term effects of bromocriptine in the treatment of parkinsonian patients.
European neurology 1989;29 Suppl 1():3-8.
1988: Sakuma H; Takase S; Mizuno Y; Teramura K; Hanew K
Hypothalamo-pituitary dopaminergic system in patients with myotonic dystrophy.
The Tohoku journal of experimental medicine 1988;156(3):291-8.
1988: Nakanishi T; Mizuno Y; Goto I; Iwata M; Kanazawa I; Kowa H; Mannen T; Nishitani H; Ogawa N; Takahashi A
A nation-wide collaborative study on the long-term effects of bromocriptine in patients with Parkinson's disease. First interim report in Japan.
European neurology 1988;28 Suppl 1():3-8.
1986: Tanaka Y; Niijima K; Mizuno Y; Yoshida M
Changes in gamma-aminobutyrate, glutamate, aspartate, glycine, and taurine contents in the striatum after unilateral nigrostriatal lesions in rats.
Experimental neurology 1986;91(2):259-68.
1985: Toyokura Y; Mizuno Y; Kase M; Sobue I; Kuroiwa Y; Narabayashi H; Uono M; Nakanishi T; Kameyama M; Ito H
Effects of bromocriptine on parkinsonism. A nation-wide collaborative double-blind study.
Acta neurologica Scandinavica 1985;72(2):157-70.
1985: Saito T; Mizuno Y; Yoshida M
[Differential diagnosis of parkinsonism based on a semiquantitative scoring system--chiefly to discriminate two major causes, paralysis agitans and vascular parkinsonism]
Rinsho shinkeigaku = Clinical neurology 1985;25(5):591-6.
1984: Katsuki T; Shimizu N; Mizuno Y
[Onset-and end-of-dose dyskinesias induced by L-dopa treatment in a patient with juvenile parkinsonism]
No to shinkei = Brain and nerve 1984;36(12):1201-5.
1984: Mizuno Y; Joshita Y; Yoshida M; Kaneko J; Tanaka Y; Nagatsuka Y
[Effects of the "drug holiday" on problems of long-term levodopa therapy against Parkinson's disease]
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 1984;73(4):474-80.
1984: Tanaka Y; Mizuno Y
[GABA, glutamate, aspartate, glycine, and taurine contents in spinocerebellar degeneration and parkinsonism]
Rinsho shinkeigaku = Clinical neurology 1984;24(3):256-63.
1983: Mizuno Y; Joshita Y
[Superoxide dismutase activities in multi-system degeneration and parkinsonism]
Rinsho shinkeigaku = Clinical neurology 1983;23(3):203-11.
1982: Mizuno Y
[A study on long-term levodopa therapy in Parkinson's disease]
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 1982;71(11):1553-9.
1981: Seki J; Arakawa Y; Imai K; Tamura Z; Yoshiue S; Mizuno Y; Yamada K; Matsue M; Narabayashi H
High-performance liquid chromatographic determination of L-3,4-dihydroxy-phenylalanine (L-DOPA) and its metabolites in the urine of patients with Parkinson's disease, control patients and normal subjects after oral administration of L-DOPA.
Chemical & pharmaceutical bulletin 1981;29(3):789-95.
1979: Mizuno Y; Ariga T
[Cerebrospinal fluid homovanillic acid in paralysis agitans and spinocerebellar degeneration (author's transl)]
Rinsho shinkeigaku = Clinical neurology 1979;19(6):367-71.
1979: Mizuno Y
[Cerebrospinal fluid methoxyhydroxy-phenylene glycol in Parkinson's disease and spinocerebellar degeneration (author's transl)]
No to shinkei = Brain and nerve 1979;31(3):309-12.
1978: Mizuno Y
[Striano-nigral degeneration]
Nippon rinsho. Japanese journal of clinical medicine 1978;Suppl():1720-1.
1977: Mizuno Y
Simple gas chromatographic analysis of plasma dopa and dopamine.
Clinica chimica acta; international journal of clinical chemistry 1977;74(1):11-9.
1976: Mizuno Y
[Effects and side effects of levodopa in parkinsonism - results of a collaborative study. (3) Side effects of levodopa]
Rinsho shinkeigaku = Clinical neurology 1976;16(12):874-6.
1976: Mizuno Y; Yoshida M; Obayashi T; Ueki A
[Combined treatment of Parkinsonism with L-dopa and peripheral dopa decarboxylase inhibitors--clinical course of 13 cases and levels of serum/dopa and dopamine]
Rinsho shinkeigaku = Clinical neurology 1976;16(7):511-9.
1975: Yoshida M; Mizuno Y
[Physiology and pharmacology of extrapyramidal tract]
Nippon rinsho. Japanese journal of clinical medicine 1975;33(10):2964-77.

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