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Yoshikuni Mizuno

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Saori Miyakawa; Yoshikuni Mizuno; Sayaka Funabe; Nobutaka Hattori; Masaaki Ichinoe; Tetuo Mikami; Hideo Mori; Shigeo Murayama; Kazutoshi Nishiyama; Mieko Ogino; Makoto Saegusa; Yasushi Shimo; Akiko Uchino; Hideki Mochizuki
Lewy body pathology in a patient with a homozygous parkin deletion.
Hideki Shimura; Yoshikuni Mizuno; Nobutaka Hattori
Parkin and Parkinson disease.
Yoshikuni Mizuno; Werner Poewe; Olivier Rascol; Akiko Sarashina; Anthony H V Schapira; Mitsutoshi Yamamoto; Paolo Barone; Kazuko Hasegawa; Nobutaka Hattori; Robert A Hauser; Tatsuro Kagimura; Sadako Kuno
Efficacy and safety of extended- versus immediate-release pramipexole in Japanese patients with advanced and (L)-dopa-undertreated Parkinson disease: a double-blind, randomized trial.

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2013: Saori Miyakawa; Yoshikuni Mizuno; Sayaka Funabe; Nobutaka Hattori; Masaaki Ichinoe; Tetuo Mikami; Hideo Mori; Shigeo Murayama; Kazutoshi Nishiyama; Mieko Ogino; Makoto Saegusa; Yasushi Shimo; Akiko Uchino; Hideki Mochizuki
Lewy body pathology in a patient with a homozygous parkin deletion.
Movement disorders : official journal of the Movement Disorder Society 2013;28(3):388-91.
2012: Hideki Shimura; Yoshikuni Mizuno; Nobutaka Hattori
Parkin and Parkinson disease.
Clinical chemistry 2012;58(8):1260-1.
2012: Yoshikuni Mizuno; Werner Poewe; Olivier Rascol; Akiko Sarashina; Anthony H V Schapira; Mitsutoshi Yamamoto; Paolo Barone; Kazuko Hasegawa; Nobutaka Hattori; Robert A Hauser; Tatsuro Kagimura; Sadako Kuno
Efficacy and safety of extended- versus immediate-release pramipexole in Japanese patients with advanced and (L)-dopa-undertreated Parkinson disease: a double-blind, randomized trial.
Clinical neuropharmacology 2012;35(4):174-81.
2012: Kohei Shimada; Atsuko Shinohara; Takashi Ueno; Momoko Chiba; Koichi Ishiguro; Masako Itaya; Taiki Kambe; Miyuki Kunichika; Shin-Ei Matsumoto; Yoshikuni Mizuno; Hideo Mori; Yumiko Motoi; Nobutaka Hattori
Long-term oral lithium treatment attenuates motor disturbance in tauopathy model mice: implications of autophagy promotion.
Neurobiology of disease 2012;46(1):101-8.
2012: Yoichi Imaizumi; Daisuke Ito; Tetsuro Kobayashi; Masato Koike; Arifumi Kosakai; Naoko Kuzumaki; Yoshikuni Mizuno; Noboru Mizushima; Hideki Mochizuki; Atsushi Nakanishi; Tomoko Nihira; Manabu Ohyama; Yohei Okada; Wado Akamatsu; Masayuki Amagai; Manabu Funayama; Nobutaka Hattori; Hideki Hayakawa; Kozo Hayashi; Akiyoshi Hirayama; Takako Hishiki; Shigeto Sato; Masanobu Shouji; Tomoyoshi Soga; Makoto Suematsu; Norihiro Suzuki; Masashi Takanashi; Yasuo Uchiyama; Takuya Yagi; Hideyuki Okano
Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue.
Molecular brain 2012;5():35.
2011: Tomoko Nihira; Takashi Shimada; Toru Yasuda; Yukihiko Hirai; Yoshikuni Mizuno; Hideki Mochizuki
Adeno-associated viral vector-mediated gene transduction in mesencephalic slice culture.
Journal of neuroscience methods 2011;201(1):55-60.
2011: Naomi Seki; Yuji K Takahashi; Hiroyuki Tomiyama; Peter St George-Hyslop; Jun Goto; Nobutaka Hattori; Anthony E Lang; Connie Marras; Yoshikuni Mizuno; Shigeo Murayama; Ekaterina Rogaeva; Shoji Tsuji
Comprehensive mutational analysis of LRRK2 reveals variants supporting association with autosomal dominant Parkinson's disease.
Journal of human genetics 2011;56(9):671-5.
2011: Toru Yasuda; Nobutaka Hattori; Hideki Hayakawa; Koichi Miyake; Yoshikuni Mizuno; Makiko Nagai; Yasuto Nakata; Tomoko Nihira; Yong-Ri Ren; Takashi Shimada; Masahiko Takada; Hideki Mochizuki
Parkin-mediated protection of dopaminergic neurons in a chronic MPTP-minipump mouse model of Parkinson disease.
Journal of neuropathology and experimental neurology 2011;70(8):686-97.
2011: Taiki Kambe; Yumiko Motoi; Ran Inoue; Nobuhiko Kojima; Norihiro Tada; Tetsuya Kimura; Naruhiko Sahara; Shunji Yamashita; Tatsuya Mizoroki; Akihiko Takashima; Kohei Shimada; Koichi Ishiguro; Hiroshi Mizuma; Hirotaka Onoe; Yoshikuni Mizuno; Nobutaka Hattori
Differential regional distribution of phosphorylated tau and synapse loss in the nucleus accumbens in tauopathy model mice.
Neurobiology of disease 2011;42(3):404-14.
2011: Koji Kamagata; Yumiko Motoi; Masaaki Hori; Michimasa Suzuki; Atsushi Nakanishi; Keigo Shimoji; Shinsuke Kyougoku; Ryohei Kuwatsuru; Keisuke Sasai; Osamu Abe; Yoshikuni Mizuno; Shigeki Aoki; Nobutaka Hattori
Posterior hypoperfusion in Parkinson's disease with and without dementia measured with arterial spin labeling MRI.
Journal of magnetic resonance imaging : JMRI 2011;33(4):803-7.
2010: Momo Tani; Hideki Hayakawa; Toru Yasuda; Tomoko Nihira; Nobutaka Hattori; Yoshikuni Mizuno; Hideki Mochizuki
Ectopic expression of α-synuclein affects the migration of neural stem cells in mouse subventricular zone.
Journal of neurochemistry 2010;115(4):854-63.
2010: Manabu Funayama; Hiroyuki Tomiyama; Ruey-Meei Wu; Kotaro Ogaki; Hiroyo Yoshino; Yoshikuni Mizuno; Nobutaka Hattori
Rapid screening of ATP13A2 variant with high-resolution melting analysis.
Movement disorders : official journal of the Movement Disorder Society 2010;25(14):2434-7.
2010: Lin Li; Manabu Funayama; Hiroyuki Tomiyama; Yuanzhe Li; Hiroyo Yoshino; Ryogen Sasaki; Yasumasa Kokubo; Shigeki Kuzuhara; Yoshikuni Mizuno; Nobutaka Hattori
No evidence for pathogenic role of GIGYF2 mutation in Parkinson disease in Japanese patients.
Neuroscience letters 2010;479(3):245-8.
2010: Yoshikuni Mizuno; Kazuko Hasegawa; Tomoyoshi Kondo; Sadako Kuno; Mitsutoshi Yamamoto
Clinical efficacy of istradefylline (KW-6002) in Parkinson's disease: a randomized, controlled study.
Movement disorders : official journal of the Movement Disorder Society 2010;25(10):1437-43.
2009: Shuichi Asakawa; Nobutaka Hattori; Atsushi Shimizu; Yoshiko Shimizu; Shinsei Minoshima; Yoshikuni Mizuno; Nobuyoshi Shimizu
Analysis of eighteen deletion breakpoints in the parkin gene.
Biochemical and biophysical research communications 2009;389(1):181-6.
2009: Angelo Antonini; Eduardo Tolosa; Yoshikuni Mizuno; Mitsutoshi Yamamoto; Werner Poewe
A reassessment of risks and benefits of dopamine agonists in Parkinson's disease.
Lancet neurology 2009;8(10):929-37.
2009: Kenya Nishioka; Owen A Ross; Kenji Ishii; Jennifer Kachergus; Kiichi Ishiwata; Mayumi Kitagawa; Satoshi Kono; Tomokazu Obi; Koichi Mizoguchi; Yuichi Inoue; H Imai; Masashi Takanashi; Yoshikuni Mizuno; Matthew J Farrer; Nobutaka Hattori
Expanding the clinical phenotype of SNCA duplication carriers.
Movement disorders : official journal of the Movement Disorder Society 2009;24(12):1811-9.
2009: Kumi Sasaki; Hideki Shimura; Masako Itaya; Ryota Tanaka; Hideo Mori; Yoshikuni Mizuno; Kenneth S Kosik; Shigeki Tanaka; Nobutaka Hattori
Excitatory amino acid transporter 2 associates with phosphorylated tau and is localized in neurofibrillary tangles of tauopathic brains.
FEBS letters 2009;583(13):2194-200.
2009: Kahori Shiba; Takeo Arai; Shigeto Sato; Shin-ichiro Kubo; Yusuke Ohba; Yoshikuni Mizuno; Nobutaka Hattori
Parkin stabilizes PINK1 through direct interaction.
Biochemical and biophysical research communications 2009;383(3):331-5.
2009: Hiroyuki Tomiyama; Yuanzhe Li; Hiroyo Yoshino; Yoshikuni Mizuno; Shin-Ichiro Kubo; Tatsushi Toda; Nobutaka Hattori
Mutation analysis for DJ-1 in sporadic and familial parkinsonism: screening strategy in parkinsonism.
Neuroscience letters 2009;455(3):159-61.
2009: Genko Oyama; Akito Hayashi; Yoshikuni Mizuno; Nobutaka Hattori
Mechanism and treatment of dropped head syndrome associated with parkinsonism.
Parkinsonism & related disorders 2009;15(3):181-6.
2009: Jiro Fukae; Shigeto Sato; Kahori Shiba; Ken-ichi Sato; Hideo Mori; Philip A Sharp; Yoshikuni Mizuno; Nobutaka Hattori
Programmed cell death-2 isoform1 is ubiquitinated by parkin and increased in the substantia nigra of patients with autosomal recessive Parkinson's disease.
FEBS letters 2009;583(3):521-5.
2009: Toru Yasuda; Tomoko Nihira; Yong-Ri Ren; Xu-Qing Cao; Keiichiro Wada; Rieko Setsuie; Tomohiro Kabuta; Keiichiro Wada; Nobutaka Hattori; Yoshikuni Mizuno; Hideki Mochizuki
Effects of UCH-L1 on alpha-synuclein over-expression mouse model of Parkinson's disease.
Journal of neurochemistry 2009;108(4):932-44.
2009: Kazunari Momma; Manabu Funayama; Yuanzhe Li; Hiroshi Ichinose; Kazuo Motoyoshi; Nobutaka Hattori; Yoshikuni Mizuno; Keiko Kamakura
A new mutation in the GCH1 gene presents as early-onset Parkinsonism.
Parkinsonism & related disorders 2009;15(2):160-1.
2009: Naoki Ichikawa; Kazuhisa Iwabuchi; Hidetake Kurihara; Kumiko Ishii; Toshihide Kobayashi; Takako Sasaki; Nobutaka Hattori; Yoshikuni Mizuno; Kentaro Hozumi; Yoshihiko Yamada; Eri Arikawa-Hirasawa
Binding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowth.
Journal of cell science 2009;122(Pt 2):289-99.
2008: Hiroyuki Tomiyama; Yasumasa Kokubo; Ryogen Sasaki; Yuanzhe Li; Yoko Imamichi; Manabu Funayama; Yoshikuni Mizuno; Nobutaka Hattori; Shigeki Kuzuhara
Mutation analyses in amyotrophic lateral sclerosis/parkinsonism-dementia complex of the Kii peninsula, Japan.
Movement disorders : official journal of the Movement Disorder Society 2008;23(16):2344-8.
2008: Manabu Funayama; Yuanzhe Li; Tak-Hong Tsoi; Ching-Wan Lam; Takekazu Ohi; Shogo Yazawa; Eiichiro Uyama; Ruth Djaldetti; Eldad Melamed; Hiroyo Yoshino; Yoko Imamichi; Hiroshi Takashima; Kenya Nishioka; Kenichi Sato; Hiroyuki Tomiyama; Shin-Ichiro Kubo; Yoshikuni Mizuno; Nobutaka Hattori
Familial Parkinsonism with digenic parkin and PINK1 mutations.
Movement disorders : official journal of the Movement Disorder Society 2008;23(10):1461-5.
2008: Yoshikuni Mizuno; Nobutaka Hattori; Shin-Ichiro Kubo; Shigeto Sato; Kenya Nishioka; Taku Hatano; Hiroyuki Tomiyama; Manabu Funayama; Yutaka Machida; Hideki Mochizuki
Progress in the pathogenesis and genetics of Parkinson's disease.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2008;363(1500):2215-27.
2008: Ryuya Kumazawa; Hiroyuki Tomiyama; Yuanzhe Li; Yoko Imamichi; Manabu Funayama; Hiroyo Yoshino; Fusako Yokochi; Toshihiro Fukusako; Yasushi Takehisa; Kenichi Kashihara; Tomoyoshi Kondo; Bulent Elibol; Sevasti Bostantjopoulou; Tatsushi Toda; Hirohide Takahashi; Fumihito Yoshii; Yoshikuni Mizuno; Nobutaka Hattori
Mutation analysis of the PINK1 gene in 391 patients with Parkinson disease.
Archives of neurology 2008;65(6):802-8.
2008: Kazuo Yamashiro; Miki Komine-Kobayashi; Taku Hatano; Takao Urabe; Hideki Mochizuki; Nobutaka Hattori; Yoshitaka Iwama; Hiroyuki Daida; Michi Sakai; Takeo Nakayama; Yoshikuni Mizuno
The frequency of cardiac valvular regurgitation in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2008;23(7):935-41.
2008: Y P Ning; K Kanai; Hiroyuki Tomiyama; Yuanzhe Li; Manabu Funayama; Hiroyo Yoshino; Shigeto Sato; Masato Asahina; S Kuwabara; Atsushi Takeda; T Hattori; Yoshikuni Mizuno; Nobutaka Hattori
PARK9-linked parkinsonism in eastern Asia: mutation detection in ATP13A2 and clinical phenotype.
Neurology 2008;70(16 Pt 2):1491-3.
2008: Kimiko Obi; Haruhiko Akiyama; Hiromi Kondo; Yoko Shimomura; Masato Hasegawa; Takeshi Iwatsubo; Yoshikuni Mizuno; Hideki Mochizuki
Relationship of phosphorylated alpha-synuclein and tau accumulation to Abeta deposition in the cerebral cortex of dementia with Lewy bodies.
Experimental neurology 2008;210(2):409-20.
2008: Tomokazu Obi; K Nishioka; O A Ross; T Terada; K Yamazaki; A Sugiura; M Takanashi; Kouichi Mizoguchi; H Mori; Yoshikuni Mizuno; Nobutaka Hattori
Clinicopathologic study of a SNCA gene duplication patient with Parkinson disease and dementia.
Neurology 2008;70(3):238-41.
2008: Hiroyuki Tomiyama; Ikuko Mizuta; Yuanzhe Li; Manabu Funayama; Hiroyo Yoshino; Lin Li; Miho Murata; Mitsutoshi Yamamoto; Shin-Ichiro Kubo; Yoshikuni Mizuno; Tatsushi Toda; Nobutaka Hattori
LRRK2 P755L variant in sporadic Parkinson's disease.
Journal of human genetics 2008;53(11-12):1012-5.
2008: Hideki Oizumi; Hiromi Hayashita-Kinoh; Hideki Hayakawa; Hiroyuki Arai; Tsuyoshi Furuya; Yong-Ri Ren; Toru Yasuda; Tatsunori Seki; Yoshikuni Mizuno; Hideki Mochizuki
Alteration in the differentiation-related molecular expression in the subventricular zone in a mouse model of Parkinson's disease.
Neuroscience research 2008;60(1):15-21.
2007: Bruno Dubois; David J Burn; Christopher G Goetz; Dag Aarsland; Richard Brown; Gerald A Broe; dennis dickson; Charles Duyckaerts; Jeffrey L Cummings; S Gauthier; Amos D Korczyn; Andrew J Lees; Richard Levy; Irene Litvan; Yoshikuni Mizuno; Ian G McKeith; C Warren Olanow; Werner Poewe; Cristina Sampaio; Eduardo Tolosa; Murat Emre
Diagnostic procedures for Parkinson's disease dementia: recommendations from the movement disorder society task force.
Movement disorders : official journal of the Movement Disorder Society 2007;22(16):2314-24.
2007: Yoshikuni Mizuno
[Discovery of the parkin gene; the gene for young onset autosomal recessive parkinsonism (AR)].
Rinshō shinkeigaku = Clinical neurology 2007;47(11):752-6.
2007: Yoshikuni Mizuno; Takashi Abe; Kazuko Hasegawa; Sadako Kuno; Tomoyoshi Kondo; Mitsutoshi Yamamoto; Mitsuyoshi Nakashima; Ichiro Kanazawa
Ropinirole is effective on motor function when used as an adjunct to levodopa in Parkinson's disease: STRONG study.
Movement disorders : official journal of the Movement Disorder Society 2007;22(13):1860-5.
2007: Murat Emre; Dag Aarsland; Richard Brown; David J Burn; Charles Duyckaerts; Yoshikuni Mizuno; Gerald A Broe; Jeffrey L Cummings; dennis dickson; S Gauthier; Jennifer Goldman; Christopher G Goetz; Amos D Korczyn; Andrew J Lees; Richard Levy; Irene Litvan; Ian G McKeith; Warren Olanow; Werner Poewe; Niall Quinn; Cristina Sampaio; Eduardo Tolosa; Bruno Dubois
Clinical diagnostic criteria for dementia associated with Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2007;22(12):1689-707; quiz 1837.
2007: Toru Yasuda; Momo Fukuda-Tani; Tomoko Nihira; Keiichiro Wada; Nobutaka Hattori; Yoshikuni Mizuno; Hideki Mochizuki
Correlation between levels of pigment epithelium-derived factor and vascular endothelial growth factor in the striatum of patients with Parkinson's disease.
Experimental neurology 2007;206(2):308-17.
2007: Yukiko Takata; Kazuyuki Noda; Kenji Fujishima; Nobutaka Hattori; Yoshikuni Mizuno; Yasuyuki Okuma
[A case of neuralgic amyotrophy in the lower extremity (lumbosacral radiculoplexus neuropathy)].
Brain and nerve = Shinkei kenkyū no shinpo 2007;59(4):435-8.
2007: Kenju Hara; Yoshio Momose; Susumu Tokiguchi; Mitsuteru Shimohata; Kenshi Terajima; Osamu Onodera; Akiyoshi Kakita; Mitsunori Yamada; Hitoshi Takahashi; Motoyuki Hirasawa; Yoshikuni Mizuno; Katsuhisa Ogata; Jun Goto; Ichiro Kanazawa; Masatoyo Nishizawa; Shoji Tsuji
Multiplex families with multiple system atrophy.
Archives of neurology 2007;64(4):545-51.
2007: Taku Hatano; Shin-Ichiro Kubo; Satoshi Imai; Masahiro Maeda; Kiyoshi Ishikawa; Yoshikuni Mizuno; Nobutaka Hattori
Leucine-rich repeat kinase 2 associates with lipid rafts.
Human molecular genetics 2007;16(6):678-90.
2007: Hideki Hayakawa; Hiromi Hayashita-Kinoh; Tomoko Nihira; Tatsunori Seki; Yoshikuni Mizuno; Hideki Mochizuki
The isolation of neural stem cells from the olfactory bulb of Parkinson's disease model.
Neuroscience research 2007;57(3):393-8.
2007: Makio Mogi; Tomoyoshi Kondo; Yoshikuni Mizuno; Toshiharu Nagatsu
p53 protein, interferon-gamma, and NF-kappaB levels are elevated in the parkinsonian brain.
Neuroscience letters 2007;414(1):94-7.
2007: Manabu Funayama; Yuanzhe Li; Hiroyuki Tomiyama; Hiroyo Yoshino; Yoko Imamichi; Mitsutoshi Yamamoto; Miho Murata; Tatsushi Toda; Yoshikuni Mizuno; Nobutaka Hattori
Leucine-rich repeat kinase 2 G2385R variant is a risk factor for Parkinson disease in Asian population.
Neuroreport 2007;18(3):273-5.
2007: Jiro Fukae; Yoshikuni Mizuno; Nobutaka Hattori
Mitochondrial dysfunction in Parkinson's disease.
Mitochondrion 2007;7(1-2):58-62.
2007: Takeo Arai; Kenji Fujishima; Hirokazu Kobayashi; Takuji Yamamoto; Kentaro Mori; Minoru Maeda; Yoshikuni Mizuno; Yasuyuki Okuma
Pseudoathetosis caused by migrated cervical disc.
Parkinsonism & related disorders 2007;13(1):59-61.
2007: Satoshi Kono; Kentaro Shirakawa; Yasuomi Ouchi; Masanobu Sakamoto; Hiroyuki Ida; Takeshi Sugiura; Hiroyuki Tomiyama; Hitoshi Suzuki; Yoshitomo Takahashi; Hiroaki Miyajima; Nobutaka Hattori; Yoshikuni Mizuno
Dopaminergic neuronal dysfunction associated with parkinsonism in both a Gaucher disease patient and a carrier.
Journal of the neurological sciences 2007;252(2):181-4.
2007: Toru Yasuda; Shigehiro Miyachi; Ryo Kitagawa; K Wada; T Nihira; Yong-Ri Ren; Yukihiko Hirai; N Ageyama; K Terao; Takashi Shimada; Masahiko Takada; Yoshikuni Mizuno; Hideki Mochizuki
Neuronal specificity of alpha-synuclein toxicity and effect of Parkin co-expression in primates.
Neuroscience 2007;144(2):743-53.
2007: Yoshikuni Mizuno; Nobutaka Hattori; Hideki Mochizuki
Genetic aspects of Parkinson's disease.
Handbook of clinical neurology 2007;83():217-44.
2007: Momo Tani; Shihoko Natori; Kazuyuki Noda; Kenji Fujishima; Nobutaka Hattori; Yoshikuni Mizuno; Yasuyuki Okuma
Isolated reversible splenial lesion in adult meningitis: a case report and review of the literature.
Internal medicine (Tokyo, Japan) 2007;46(18):1597-600.
2007: Yoshikuni Mizuno; Ichiro Kanazawa; Sadako Kuno; Nobuo Yanagisawa; Mitsutoshi Yamamoto; Tomoyoshi Kondo
Placebo-controlled, double-blind dose-finding study of entacapone in fluctuating parkinsonian patients.
Movement disorders : official journal of the Movement Disorder Society 2007;22(1):75-80.
2007: Rieko Setsuie; Yu-Lai Wang; Hideki Mochizuki; Hitoshi Osaka; Hideki Hayakawa; Nobutsune Ichihara; Hang Li; Akiko Furuta; Yae Sano; Ying-Jie Sun; Jungkee Kwon; Tomohiro Kabuta; Kenji Yoshimi; Shunsuke Aoki; Yoshikuni Mizuno; Mami Noda; Keiji Wada
Dopaminergic neuronal loss in transgenic mice expressing the Parkinson's disease-associated UCH-L1 I93M mutant.
Neurochemistry international 2007;50(1):119-29.
2006: Kazuo Yamakawa; Masashi Takanashi; Masao Watanabe; Noriyuki Nakamura; Tomonori Kobayashi; Masato Hasegawa; Yoshikuni Mizuno; Shigeki Tanaka; Hideo Mori
Pathological and biochemical studies on a case of Pick disease with severe white matter atrophy.
Neuropathology : official journal of the Japanese Society of Neuropathology 2006;26(6):586-91.
2006: Kenya Nishioka; Kenji Fujishima; Hirokazu Kobayashi; Yoshikuni Mizuno; Yasuyuki Okuma
An extremely unusual presentation of varicella zoster viral infection of cranial nerves mimicking Garcin syndrome.
Clinical neurology and neurosurgery 2006;108(8):772-4.
2006: Xu-Qing Cao; Hiroyuki Arai; Yong-Ri Ren; Hideki Oizumi; Ning Zhang; Shiho Seike; Tsuyoshi Furuya; Toru Yasuda; Yoshikuni Mizuno; Hideki Mochizuki
Recombinant human granulocyte colony-stimulating factor protects against MPTP-induced dopaminergic cell death in mice by altering Bcl-2/Bax expression levels.
Journal of neurochemistry 2006;99(3):861-7.
2006: Shigeto Sato; Tomoki Chiba; Shingo Nishiyama; Takeharu Kakiuchi; Hideo Tsukada; Taku Hatano; Takahiro Fukuda; Yasunobu Yasoshima; Nobuyuki Kai; Kazuto Kobayashi; Yoshikuni Mizuno; Keiji Tanaka; Nobutaka Hattori
Decline of striatal dopamine release in parkin-deficient mice shown by ex vivo autoradiography.
Journal of neuroscience research 2006;84(6):1350-7.
2006: Atsuko Nakamura; Toshiaki Kitami; Hideo Mori; Yoshikuni Mizuno; Nobutaka Hattori
Nuclear localization of the 20S proteasome subunit in Parkinson's disease.
Neuroscience letters 2006;406(1-2):43-8.
2006: Makoto Wada; Kenji Yoshimi; Noriyuki Higo; Yong-Ri Ren; Hideki Mochizuki; Yoshikuni Mizuno; Shigeru Kitazawa
Statistical parametric mapping of immunopositive cell density.
Neuroscience research 2006;56(1):96-102.
2006: Yong-Ri Ren; Yoichiro Nishida; Kenji Yoshimi; Toru Yasuda; Kou-ichi Jishage; Toshiki Uchihara; Takanori Yokota; Yoshikuni Mizuno; Hideki Mochizuki
Genetic vitamin E deficiency does not affect MPTP susceptibility in the mouse brain.
Journal of neurochemistry 2006;98(6):1810-6.
2006: Kenichi Sato; Taku Hatano; Kazuo Yamashiro; Maki Kagohashi; Kenya Nishioka; Nana Izawa; Hideki Mochizuki; Nobutaka Hattori; Hideo Mori; Yoshikuni Mizuno
Prognosis of Parkinson's disease: time to stage III, IV, V, and to motor fluctuations.
Movement disorders : official journal of the Movement Disorder Society 2006;21(9):1384-95.
2006: Takeo Arai; Jiro Fukae; Taku Hatano; Shin-ichiro Kubo; Toshio Ohtsubo; Yusaku Nakabeppu; Hideo Mori; Yoshikuni Mizuno; Nobutaka Hattori
Up-regulation of hMUTYH, a DNA repair enzyme, in the mitochondria of substantia nigra in Parkinson's disease.
Acta neuropathologica 2006;112(2):139-45.
2006: Hiroyuki Tomiyama; Yuanzhe Li; Manabu Funayama; Kazuko Hasegawa; Hiroyo Yoshino; Shin-Ichiro Kubo; Kenichi Sato; Tatsuya Hattori; Chin-Song Lu; Rivka Inzelberg; Ruth Djaldetti; Eldad Melamed; Rim Amouri; Neziha Gouider-Khouja; Faycal Hentati; Yasuko Hatano; Mei Wang; Yoko Imamichi; Koichi Mizoguchi; Hiroaki Miyajima; Fumiya Obata; Tatsushi Toda; Matthew J Farrer; Yoshikuni Mizuno; Nobutaka Hattori
Clinicogenetic study of mutations in LRRK2 exon 41 in Parkinson's disease patients from 18 countries.
Movement disorders : official journal of the Movement Disorder Society 2006;21(8):1102-8.
2006: Shin-ichiro Kubo; Nobutaka Hattori; Yoshikuni Mizuno
Recessive Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2006;21(7):885-93.
2006: Terubumi Watanabe; Ning Zhang; Meizi Liu; Ryota Tanaka; Yoshikuni Mizuno; Takao Urabe
Cilostazol protects against brain white matter damage and cognitive impairment in a rat model of chronic cerebral hypoperfusion.
Stroke; a journal of cerebral circulation 2006;37(6):1539-45.
2006: Yuji Ueno; Kenji Fujishima; Hirokazu Kobayashi; Yoshikuni Mizuno; Yasuyuki Okuma
Cortical myoclonus due to hypocalcemia 12 years after thyroidectomy.
Clinical neurology and neurosurgery 2006;108(4):400-3.
2006: Heii Arai; T Furuya; Yoshikuni Mizuno; H Mochizuki
Inflammation and infection in Parkinson's disease.
Histology and histopathology 2006;21(6):673-8.
2006: Keiichirou Wada; Hiroyuki Arai; Masashi Takanashi; Jiro Fukae; Hideki Oizumi; Toru Yasuda; Yoshikuni Mizuno; Hideki Mochizuki
Expression levels of vascular endothelial growth factor and its receptors in Parkinson's disease.
Neuroreport 2006;17(7):705-9.
2006: Shoji Yamamoto; Jiro Fukae; Hideo Mori; Yoshikuni Mizuno; Nobutaka Hattori
Positive immunoreactivity for vesicular monoamine transporter 2 in Lewy bodies and Lewy neurites in substantia nigra.
Neuroscience letters 2006;396(3):187-91.
2006: Hiromi Hayashita-Kinoh; Masanori Yamada; Takanori Yokota; Yoshikuni Mizuno; Hideki Mochizuki
Down-regulation of alpha-synuclein expression can rescue dopaminergic cells from cell death in the substantia nigra of Parkinson's disease rat model.
Biochemical and biophysical research communications 2006;341(4):1088-95.
2006: Taku Hatano; Momo Fukuda; Hiromi Shiotsuki; Hideto Miwa; Takao Urabe; Yoshikuni Mizuno
[Chronic inflammatory demyelinating polyneuropathy followed by systemic lupus erythematosus and Sjögren syndrome: a case report].
Rinshō shinkeigaku = Clinical neurology 2006;46(3):203-9.
2006: Miki Komine-Kobayashi; Ning Zhang; Meizi Liu; Ryota Tanaka; Hideaki Hara; Akimichi Osaka; Hideki Mochizuki; Yoshikuni Mizuno; Takao Urabe
Neuroprotective effect of recombinant human granulocyte colony-stimulating factor in transient focal ischemia of mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(3):402-13.
2006: Noriyuki Matsuda; Toshiaki Kitami; Toshiaki Suzuki; Yoshikuni Mizuno; Nobutaka Hattori; Keiji Tanaka
Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro.
The Journal of biological chemistry 2006;281(6):3204-9.
2006: Terubumi Watanabe; Keigo Goto; Masashi Takanashi; Hideo Mori; Hiroaki Fujii; Okio Hino; Hideki Mochizuki; Yoshikuni Mizuno
[An 80-year-old woman with progressive stroke, who had rheumatoid arthritis and antiphospholipid syndrome].
Nō to shinkei = Brain and nerve 2006;58(2):173-81.
2006: Ruiqin Liu; Asuka Suzuki; Zhiwei Guo; Yoshikuni Mizuno; Takao Urabe
Intrinsic and extrinsic erythropoietin enhances neuroprotection against ischemia and reperfusion injury in vitro.
Journal of neurochemistry 2006;96(4):1101-10.
2006: Kenya Nishioka; Shin Hayashi; Matthew J Farrer; Andrew Singleton; Hiroyo Yoshino; Hisamasa Imai; Toshiaki Kitami; Kenichi Sato; Ryu Kuroda; Hiroyuki Tomiyama; Koichi Mizoguchi; Miho Murata; Tatsushi Toda; Issei Imoto; Johji Inazawa; Yoshikuni Mizuno; Nobutaka Hattori
Clinical heterogeneity of alpha-synuclein gene duplication in Parkinson's disease.
Annals of neurology 2006;59(2):298-309.
2006: Makiko-Iijima Kitami; Toshiaki Kitami; Masami Nagahama; Mitsuo Tagaya; Seiji Hori; Akira Kakizuka; Yoshikuni Mizuno; Nobutaka Hattori
Dominant-negative effect of mutant valosin-containing protein in aggresome formation.
FEBS letters 2006;580(2):474-8.
2006: Sachio Naito; Hideki Mochizuki; Toru Yasuda; Yoshikuni Mizuno; Michihiro Furusaka; Susumu Ikeda; Tomohiro Adachi; Hirohiko M Shimizu; Junichi Suzuki; Satoru Fujiwara; Tomoko Okada; Kaori Nishikawa; Shunsuke Aoki; Keiji Wada
Characterization of multimetric variants of ubiquitin carboxyl-terminal hydrolase L1 in water by small-angle neutron scattering.
Biochemical and biophysical research communications 2006;339(2):717-25.
2006: Shigeto Sato; Tomoki Chiba; Eri Sakata; Koichi Kato; Yoshikuni Mizuno; Nobutaka Hattori; Keiji Tanaka
14-3-3eta is a novel regulator of parkin ubiquitin ligase.
The EMBO journal 2006;25(1):211-21.
2006: Hideki Mochizuki; Masanori Yamada; Yoshikuni Mizuno
Alpha-synuclein overexpression model.
Journal of neural transmission. Supplementum 2006;(70):281-4.
2006: Nobutaka Hattori; Yutaka Machida; Shigeto Sato; Kazuyuki Noda; M Iijima-Kitami; S i Kubo; Yoshikuni Mizuno
Molecular mechanisms of nigral neurodegeneration in Park2 and regulation of parkin protein by other proteins.
Journal of neural transmission. Supplementum 2006;(70):205-8.
2006: Yoshikuni Mizuno; Nobutaka Hattori; Hiroyo Yoshino; Y Hatano; K Satoh; Hiroyuki Tomiyama; Y Li
Progress in familial Parkinson's disease.
Journal of neural transmission. Supplementum 2006;(70):191-204.
2006: Kazuo Yamashiro; Terubumi Watanabe; Ryota Tanaka; Miki Komine-Kobayashi; Yoshikuni Mizuno; Takao Urabe
Clustering of risk factors increases the incidence of echolucent carotid plaque in stroke patients.
Cerebrovascular diseases (Basel, Switzerland) 2006;22(5-6):432-8.
2006: Nobukazu Miyamoto; Maki Kagohashi; Kenya Nishioka; Kenji Fujishima; Tohru Kitada; Yoshiyuki Tomita; Kentaro Mori; Minoru Maeda; Ryo Wada; Michio Matsumoto; Hideo Mori; Yoshikuni Mizuno; Yasuyuki Okuma
An autopsy case of Schilder's variant of multiple sclerosis (Schilder's disease).
European neurology 2006;55(2):103-7.
2006: Keiichiro Wada; Yumiko Motoi; Yasuko Komatsuzaki; Masashi Takanashi; Hideo Mori; Takao Urabe; Yoshikuni Mizuno
[An 81-year-old man with personality change, dementia, and gait disturbance with diffuse leukoaraiosis of the cerebral white matter].
Nō to shinkei = Brain and nerve 2006;58(1):79-90.
2005: Ian G McKeith; dennis dickson; J Lowe; M Emre; John T O'Brien; H Feldman; Jeffrey L Cummings; J E Duda; Carol F Lippa; Elaine K Perry; Dag Aarsland; Heii Arai; Clive G Ballard; Bradley Boeve; David J Burn; D Costa; T Del Ser; Bruno Dubois; Douglas Galasko; S Gauthier; Christopher G Goetz; E Gomez-Tortosa; G Halliday; Lawrence A Hansen; John Hardy; Takeshi Iwatsubo; Rajesh N. Kalaria; Daniel Kaufer; R A Kenny; Amos D Korczyn; Kenji Kosaka; Virginia M-Y Lee; Andrew J Lees; I Litvan; E Londos; Oscar L Lopez; Satoshi Minoshima; Yoshikuni Mizuno; J A Molina; E B Mukaetova-Ladinska; Florence Pasquier; Robert H Perry; J B Schulz; John Q Trojanowski; Masahito Yamada
Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium.
Neurology 2005;65(12):1863-72.
2005: Rivka Inzelberg; Nobutaka Hattori; Yoshikuni Mizuno
Dopaminergic dysfunction in unrelated, asymptomatic carriers of a single parkin mutation.
Neurology 2005;65(11):1843.
2005: Hideki Shimura; Hideo Mori; Yasuko Komatsuzaki; Kazuhiro Nakamura; Masashi Takanashi; Nobutaka Hattori; Yoshikuni Mizuno
[A 54-year-old man with familial parkinsonism, gaze palsy, and dementia].
Nō to shinkei = Brain and nerve 2005;57(12):1104-12.
2005: Xiaobing Li; Toshiaki Kitami; Mei Wang; Yoshikuni Mizuno; Nobutaka Hattori
Geographic and ethnic differences in frequencies of two polymorphisms (D/N394 and L/I272) of the parkin gene in sporadic Parkinson's disease.
Parkinsonism & related disorders 2005;11(8):485-91.
2005: Yasuji Shimo; Kennichi Sato; Hiroyuki Iwamoto; Yumiko Motoi; Hideo Mori; Takao Urabe; Yoshikuni Mizuno
[A 76-year-old woman with personality change, dementia and parkinsonism].
Nō to shinkei = Brain and nerve 2005;57(11):1011-9.
2005: Genko Oyama; Nana Izawa; Kenji Fujishima; Hirokazu Kobayashi; Yoshikuni Mizuno; Yasuyuki Okuma
[Familial amyotrophic lateral sclerosis with rapid progression].
Nō to shinkei = Brain and nerve 2005;57(11):1003-6.
2005: Carolyn F Orr; Dominic Rowe; Yoshikuni Mizuno; Hideo Mori; Linda Truong
A possible role for humoral immunity in the pathogenesis of Parkinson's disease.
Brain : a journal of neurology 2005;128(Pt 11):2665-74.
2005: Taku Hatano; Masashi Takanashi; Teiko Sumino; Ying Liu; Hideo Mori; Nobutaka Hattori; Yoshikuni Mizuno
[A 73-year-old woman with depression, dementia, and parkinsonism].
Nō to shinkei = Brain and nerve 2005;57(10):907-14.
2005: Takashi Namba; Hideki Mochizuki; Masafumi Onodera; Yoshikuni Mizuno; Hideo Namiki; Tatsunori Seki
The fate of neural progenitor cells expressing astrocytic and radial glial markers in the postnatal rat dentate gyrus.
The European journal of neuroscience 2005;22(8):1928-41.
2005: Ning Zhang; Miki Komine-Kobayashi; Ryota Tanaka; Meizi Liu; Yoshikuni Mizuno; Takao Urabe
Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal ischemia in mice brain.
Stroke; a journal of cerebral circulation 2005;36(10):2220-5.
2005: Yumiko Motoi; Hiroyuki Iwamoto; Masako Itaya; Tomonori Kobayashi; Masato Hasegawa; Minoru Yasuda; Yoshikuni Mizuno; Hideo Mori
Four-repeat tau-positive Pick body-like inclusions are distinct from classic Pick bodies.
Acta neuropathologica 2005;110(4):431-3.
2005: Masayuki Ide; Kazuo Yamada; Tomoko Toyota; Yoshimi Iwayama; Yuichi Ishitsuka; Yoshio Minabe; Kazuhiko Nakamura; Nobutaka Hattori; Takashi Asada; Yoshikuni Mizuno; Norio Mori; Takeo Yoshikawa
Genetic association analyses of PHOX2B and ASCL1 in neuropsychiatric disorders: evidence for association of ASCL1 with Parkinson's disease.
Human genetics 2005;117(6):520-7.
2005: Satoshi Orimo; Takeshi Amino; Masayuki Yokochi; Tohru Kojo; Toshiki Uchihara; Atsushi Takahashi; Koichi Wakabayashi; Hitoshi Takahashi; Nobutaka Hattori; Yoshikuni Mizuno
Preserved cardiac sympathetic nerve accounts for normal cardiac uptake of MIBG in PARK2.
Movement disorders : official journal of the Movement Disorder Society 2005;20(10):1350-3.
2005: Yoshikuni Mizuno
[In pursuit of the causes for Parkinson disease].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2005;94(9):1761-73.
2005: Shin-ichiro Kubo; Venu M Nemani; Robert J Chalkley; Malcolm D Anthony; Nobutaka Hattori; Yoshikuni Mizuno; Robert H Edwards; Doris L Fortin
A combinatorial code for the interaction of alpha-synuclein with membranes.
The Journal of biological chemistry 2005;280(36):31664-72.
2005: Jiro Fukae; Yumiko Motoi; Yasuko Komatsuzaki; Masashi Takanashi; Hideki Mochizuki; Yoshikuni Mizuno
[A 59-year-old woman with personality change and abnormal behavior followed by amyotrophy and dementia].
Nō to shinkei = Brain and nerve 2005;57(9):810-20.
2005: Yuh Machida; Makiko Lijima; Kazuhiro Nakamura; Satoshi Ota; Nobutaka Hattori; Yoshikuni Mizuno
[A 60-year-old man with intention tremor as an initial symptom followed by cerebellar ataxia, peripheral neuropathy and dementia].
Nō to shinkei = Brain and nerve 2005;57(8):710-9.
2005: Li Guo; Masako Itaya; Masashi Takanashi; Yoshikuni Mizuno; Hideo Mori
Relationship between Parkinson disease with dementia and dementia with Lewy bodies.
Parkinsonism & related disorders 2005;11(5):305-9.
2005: Kenji Yoshimi; Yong-Ri Ren; Tatsunori Seki; Masanori Yamada; Hideki Ooizumi; Masafumi Onodera; Yuko Saito; Shigeo Murayama; Hideyuki Okano; Yoshikuni Mizuno; Hideki Mochizuki
Possibility for neurogenesis in substantia nigra of parkinsonian brain.
Annals of neurology 2005;58(1):31-40.
2005: Yutaka Machida; Tomoki Chiba; Atsushi Takayanagi; Yoshikazu Tanaka; Masato Asanuma; Norio Ogawa; Akihiko Koyama; Takeshi Iwatsubo; Shosuke Ito; Poul Hening Jansen; Nobuyoshi Shimizu; Keiji Tanaka; Yoshikuni Mizuno; Nobutaka Hattori
Common anti-apoptotic roles of parkin and alpha-synuclein in human dopaminergic cells.
Biochemical and biophysical research communications 2005;332(1):233-40.
2005: Yuanzhe Li; Hiroyuki Tomiyama; Kenichi Sato; Yasuko Hatano; Hiroyo Yoshino; Masahiko Atsumi; Masataka Kitaguchi; S Sasaki; S Kawaguchi; H Miyajima; Tatsushi Toda; Yoshikuni Mizuno; Nobutaka Hattori
Clinicogenetic study of PINK1 mutations in autosomal recessive early-onset parkinsonism.
Neurology 2005;64(11):1955-7.
2005: Jiro Fukae; Shin-Ichiro Kubo; Nobutaka Hattori; Kaoru Komatsu; Masaaki Kato; Masashi Aoki; Yoshikuni Mizuno
Hoarseness due to bilateral vocal cord paralysis as an initial manifestation of familial amyotrophic lateral sclerosis.
Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 2005;6(2):122-4.
2005: Kazuyuki Noda; Toshiaki Kitami; Wei Ping Gai; Fariba Chegini; Poul Henning Jensen; Tsutomu Fujimura; Kimie Murayama; Keiji Tanaka; Yoshikuni Mizuno; Nobutaka Hattori
Phosphorylated IkappaBalpha is a component of Lewy body of Parkinson's disease.
Biochemical and biophysical research communications 2005;331(1):309-17.
2005: Jiro Fukae; Hideki Mochizuki; Rina Ohashi; Kazuko Mitani; Junya Kawada; Yoshikuni Mizuno
[Late onset hemiparkinsonism-hemiatrophy syndrome: a case report].
Rinshō shinkeigaku = Clinical neurology 2005;45(5):390-3.
2005: Naoki Ichikawa; Shingo Kasai; Nobuharu Suzuki; Norio Nishi; Shinya Oishi; Nobutaka Fujii; Yuichi Kadoya; Kozo Hatori; Yoshikuni Mizuno; Motoyoshi Nomizu; Eri Arikawa-Hirasawa
Identification of neurite outgrowth active sites on the laminin alpha4 chain G domain.
Biochemistry 2005;44(15):5755-62.
2005: Yasuko Hatano; Gyohyo Ri; Nobutaka Hattori; Yoshikuni Mizuno
[Gene abnormalities in Parkinson disease].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2005;94(4):775-81.
2005: Yasuyuki Okuma; Kenji Fujishima; Hideto Miwa; Hideo Mori; Yoshikuni Mizuno
Myoclonic tremulous movements in multiple system atrophy are a form of cortical myoclonus.
Movement disorders : official journal of the Movement Disorder Society 2005;20(4):451-6.
2005: Shigeto Sato; Yoshikuni Mizuno; Nobutaka Hattori
Urinary 8-hydroxydeoxyguanosine levels as a biomarker for progression of Parkinson disease.
Neurology 2005;64(6):1081-3.
2005: Miki Kobayashi; Taku Hatano; Shigeki Tanaka; Kazuhisa Ishi; Masashi Takanashi; Takao Urabe; Yoshikuni Mizuno
[A 67-year-old man with rt. hand resting tremor and rigidity after lt. putaminal hemorrhage].
Nō to shinkei = Brain and nerve 2005;57(3):243-53.
2005: Jiro Fukae; Masashi Takanashi; Shin-ichiro Kubo; Ken-ichi Nishioka; Yusaku Nakabeppu; Hideo Mori; Yoshikuni Mizuno; Nobutaka Hattori
Expression of 8-oxoguanine DNA glycosylase (OGG1) in Parkinson's disease and related neurodegenerative disorders.
Acta neuropathologica 2005;109(3):256-62.
2005: Yoshikuni Mizuno
[Studies on pathogenesis of Parkinson's disease].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2005;94 Suppl():66-70.
2005: Masanori Yamada; Yoshikuni Mizuno; Hideki Mochizuki
Parkin gene therapy for alpha-synucleinopathy: a rat model of Parkinson's disease.
Human gene therapy 2005;16(2):262-70.
2005: Kazuyuki Noda; Tomonori Kobayashi; Shuji Matsuoka; Masashi Takanashi; Akira Kanazawa; Yoshikuni Mizuno
[A 65-year-old man with rigid-bradykinetic parkinsonism, vertical gaze palsy, difficulty of eye-lid opening, and marked pseudo-bulbar palsy].
Nō to shinkei = Brain and nerve 2005;57(1):73-86.
2005: Kazuo Yamashiro; Makiko Kunoki; Yoshiharu Miura; Junji Tomiyama; Hideki Mochizuki; Yoshikuni Mizuno
[Posterior leukoencephalopathy syndrome presenting with bilateral ataxie optique: a case report].
Rinshō shinkeigaku = Clinical neurology 2005;45(1):13-7.
2005: Katsumi Tsuchiya; Hisao Tajima; Toyoyasu Kuwae; Takao Takeshima; Toshiya Nakano; Masaharu Tanaka; Katsuyoshi Sunaga; Yoko Fukuhara; Kenji Nakashima; Eisaku Ohama; Hideki Mochizuki; Yoshikuni Mizuno; Nobuo Katsube; Ryoichi Ishitani
Pro-apoptotic protein glyceraldehyde-3-phosphate dehydrogenase promotes the formation of Lewy body-like inclusions.
The European journal of neuroscience 2005;21(2):317-26.
2005: Darren J Moore; Li Zhang; Juan C Troncoso; Michael K Lee; Nobutaka Hattori; Yoshikuni Mizuno; Ted M Dawson; Valina Dawson
Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress.
Human molecular genetics 2005;14(1):71-84.
2004: Hiroyuki Arai; Tsuyoshi Furuya; Toru Yasuda; Masayuki Miura; Yoshikuni Mizuno; Hideki Mochizuki
Neurotoxic effects of lipopolysaccharide on nigral dopaminergic neurons are mediated by microglial activation, interleukin-1beta, and expression of caspase-11 in mice.
The Journal of biological chemistry 2004;279(49):51647-53.
2004: Keiji Tanaka; Toshiaki Suzuki; Nobutaka Hattori; Yoshikuni Mizuno
Ubiquitin, proteasome and parkin.
Biochimica et biophysica acta 2004;1695(1-3):235-47.
2004: Yoshikuni Mizuno
[Progress in the basic and clinical aspects of Parkinson's disease].
Rinshō shinkeigaku = Clinical neurology 2004;44(11):741-50.
2004: Yasuko Hatano; Kenichi Sato; B Elibol; Hiroyo Yoshino; Yasuhiro Yamamura; Vincenzo Bonifati; Hitoshi Shinotoh; Masato Asahina; S Kobayashi; A R Ng; R L Rosales; Sharon Hassin-Baer; Y Shinar; Chin-Song Lu; H C Chang; Yah-Huei Wu Chou; F Belgin Ataç; Tomonori Kobayashi; Tatsushi Toda; Yoshikuni Mizuno; Nobutaka Hattori
PARK6-linked autosomal recessive early-onset parkinsonism in Asian populations.
Neurology 2004;63(8):1482-5.
2004: Masashi Tanaka; Vicente M Cabrera; Ana M González; José M Larruga; Takeshi Takeyasu; Noriyuki Fuku; Li-Jun Guo; Raita Hirose; Yasunori Fujita; Miyuki Kurata; Ken-ichi Shinoda; Kazuo Umetsu; Yoshiji Yamada; Yoshiharu Oshida; Yuzo Sato; Nobutaka Hattori; Yoshikuni Mizuno; Yasumichi Arai; Nobuyoshi Hirose; Shigeo Ohta; Osamu Ogawa; Yasushi Tanaka; Ryuzo Kawamori; Masayo Shamoto-Nagai; Wakako Maruyama; Hiroshi Shimokata; Ryota Suzuki; Hidetoshi Shimodaira
Mitochondrial genome variation in eastern Asia and the peopling of Japan.
Genome research 2004;14(10A):1832-50.
2004: Masanori Yamada; Takeshi Iwatsubo; Yoshikuni Mizuno; Hideki Mochizuki
Overexpression of alpha-synuclein in rat substantia nigra results in loss of dopaminergic neurons, phosphorylation of alpha-synuclein and activation of caspase-9: resemblance to pathogenetic changes in Parkinson's disease.
Journal of neurochemistry 2004;91(2):451-61.
2004: Yumiko Motoi; Masako Itaya; Hideo Mori; Yoshikuni Mizuno; Tadao Iwasaki; Hiroaki Hattori; Seichi Haga; Kazuhiko Ikeda
Apolipoprotein E receptor 2 is involved in neuritic plaque formation in APP sw mice.
Neuroscience letters 2004;368(2):144-7.
2004: Yoshikuni Mizuno
[Progress in Parkinson's disease].
Nihon rinsho. Japanese journal of clinical medicine 2004;62(9):1597-600.
2004: C Warren Olanow; Yves Agid; Yoshikuni Mizuno; Alberto Albanese; Ubaldo Bonuccelli; U Bonucelli; Philippe Damier; Justo De Yebenes; Oscar S Gershanik; Mark Guttman; Francisco Grandas; Mark Hallett; Oleh Hornykiewicz; Peter Jenner; Regina Katzenschlager; William J Langston; Peter LeWitt; Eldad Melamed; M A Mena; Patrick P Michel; Catherine Mytilineou; Jose A Obeso; Werner Poewe; Niall Quinn; Rita Raisman-Vozari; Ali H Rajput; Olivier Rascol; Cristina Sampaio; Fabrizio Stocchi
Levodopa in the treatment of Parkinson's disease: current controversies.
Movement disorders : official journal of the Movement Disorder Society 2004;19(9):997-1005.
2004: Yasuko Hatano; Yuanzhe Li; Kenichi Sato; Shuichi Asakawa; Yasuhiro Yamamura; Hiroyuki Tomiyama; Hiroyo Yoshino; Masato Asahina; Susumu Kobayashi; Sharon Hassin-Baer; Chin-Song Lu; Arlene R Ng; Raymond L Rosales; Nobuyoshi Shimizu; Tatsushi Toda; Yoshikuni Mizuno; Nobutaka Hattori
Novel PINK1 mutations in early-onset parkinsonism.
Annals of neurology 2004;56(3):424-7.
2004: Nobutaka Hattori; Yoshikuni Mizuno
Pathogenetic mechanisms of parkin in Parkinson's disease.
Lancet 2004;364(9435):722-4.
2004: Donald B Calne; Yoshikuni Mizuno
The neuromythology of Parkinson's Disease.
Parkinsonism & related disorders 2004;10(5):319-22.
2004: Yumi Shimo-Nakanishi; Takeshi Hasebe; Asuka Suzuki; Hideki Mochizuki; Takashi Nomiyama; Yasushi Tanaka; Isao Nagaoka; Yoshikuni Mizuno; Takao Urabe
Functional effects of NAD(P)H oxidase p22(phox) C242T mutation in human leukocytes and association with thrombotic cerebral infarction.
Atherosclerosis 2004;175(1):109-15.
2004: Youichirou Higashi; Masato Asanuma; Ikuko Miyazaki; Nobutaka Hattori; Yoshikuni Mizuno; Norio Ogawa
Parkin attenuates manganese-induced dopaminergic cell death.
Journal of neurochemistry 2004;89(6):1490-7.
2004: Ryota Tanaka; Kazuo Yamashiro; Hideki Mochizuki; Nei Cho; Masafumi Onodera; Yoshikuni Mizuno; Takao Urabe
Neurogenesis after transient global ischemia in the adult hippocampus visualized by improved retroviral vector.
Stroke; a journal of cerebral circulation 2004;35(6):1454-9.
2004: Miki Komine-Kobayashi; Nei Chou; Hideki Mochizuki; Atsuhito Nakao; Yoshikuni Mizuno; Takao Urabe
Dual role of Fcgamma receptor in transient focal cerebral ischemia in mice.
Stroke; a journal of cerebral circulation 2004;35(4):958-63.
2004: Yumiko Motoi; Masashi Takanashi; Masako Itaya; Kazuhiko Ikeda; Yoshikuni Mizuno; Hideo Mori
Glial localization of four-repeat tau in atypical progressive supranuclear palsy.
Neuropathology : official journal of the Japanese Society of Neuropathology 2004;24(1):60-5.
2004: Maki Kagohashi; Yasuyuki Okuma; Kenji Fujishima; Tohru Kitada; Yoshikuni Mizuno
Blepharospasm associated with multiple system atrophy: a case report and review of the literature.
Parkinsonism & related disorders 2004;10(3):169-71.
2004: Tsuyoshi Furuya; Hideki Hayakawa; Masanori Yamada; Kenji Yoshimi; Shin Hisahara; Masayuki Miura; Yoshikuni Mizuno; Hideki Mochizuki
Caspase-11 mediates inflammatory dopaminergic cell death in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(8):1865-72.
2004: Terubumi Watanabe; Yasuyuki Okuma; Kenji Fujishima; Tohru Kitada; Yasuaki Nakao; Yoshikuni Mizuno
Isolated deep cerebral venous thrombosis: an important cause for isolated mental impairment.
European neurology 2004;52(2):123-5.
2004: Masanori Yamada; M Onodera; Yoshikuni Mizuno; Hideki Mochizuki
Neurogenesis in olfactory bulb identified by retroviral labeling in normal and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated adult mice.
Neuroscience 2004;124(1):173-81.
2004: Kazuo Yamashiro; Yasuyuki Okuma; Kenji Fujishima; Keigo Goto; Yoshikuni Mizuno
Bilateral hypoglossal nerve involvement in chronic inflammatory demyelinating polyneuropathy.
European neurology 2004;51(1):45-6.
2003: Yoshito Nagano; Hiroshi Yamashita; Tetsuya Takahashi; Shosei Kishida; Takeshi Nakamura; Eizo Iseki; Nobutaka Hattori; Yoshikuni Mizuno; Akira Kikuchi; Masayasu Matsumoto
Siah-1 facilitates ubiquitination and degradation of synphilin-1.
The Journal of biological chemistry 2003;278(51):51504-14.
2003: Yuko Hattori; Tatsuya Hattori; Ei-ichiro Mukai; Hideo Mori; Yoshikuni Mizuno; Yuhei Kayukawa; Tamotsu Okada; Takashi Kanbayashi
[Excessive daytime sleepiness and low CSF orexin-A/hypocretin-I levels in a patient with probable progressive supranuclear palsy].
Nō to shinkei = Brain and nerve 2003;55(12):1053-6.
2003: Se Jung Kim; Jee Young Sung; Ji Won Um; Nobutaka Hattori; Yoshikuni Mizuno; Keiji Tanaka; Seung R Paik; Jongsun Kim; Kwang Chul Chung
Parkin cleaves intracellular alpha-synuclein inclusions via the activation of calpain.
The Journal of biological chemistry 2003;278(43):41890-9.
2003: Nobutaka Hattori; Hirokazu Kobayashi; Yasuko Sasaki-Hatano; Kenichi Sato; Yoshikuni Mizuno
Familial Parkinson's disease: a hint to elucidate the mechanisms of nigral degeneration.
Journal of neurology 2003;250 Suppl 3():III2-10.
2003: Yoshikuni Mizuno; Nobuo Yanagisawa; Sadako Kuno; Mitsutoshi Yamamoto; Kazuko Hasegawa; Hideki Origasa; Hisanori Kowa
Randomized, double-blind study of pramipexole with placebo and bromocriptine in advanced Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2003;18(10):1149-56.
2003: T Hatano; Yasuyuki Okuma; M Iijima; Kenji Fujishima; K Goto; Yoshikuni Mizuno
Cervical dystonia in dentatorubral-pallidoluysian atrophy.
Acta neurologica Scandinavica 2003;108(4):287-9.
2003: Nobutaka Hattori; Yasuko Hatano; Kenichi Sato; Yoshikuni Mizuno
[Juvenile parkinsonism].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2003;92(8):1406-13.
2003: Yasuko Hatano; Hideo Mori; Kaoru Kakusaka; Tohru Kitada; Takao Urabe; Yoshikuni Mizuno
[A patient with Hashimoto's encephalopathy showing subacute global cognitive dysfunction].
Rinshō shinkeigaku = Clinical neurology 2003;43(6):360-2.
2003: Ryosuke Takahashi; Yuzuru Imai; Nobutaka Hattori; Yoshikuni Mizuno
Parkin and endoplasmic reticulum stress.
Annals of the New York Academy of Sciences 2003;991():101-6.
2003: Yasuyuki Okuma; Nobutaka Hattori; Yoshikuni Mizuno
Sensory neuropathy in autosomal recessive juvenile parkinsonism (PARK2).
Parkinsonism & related disorders 2003;9(5):313-4.
2003: Neziha Gouider-Khouja; Abdelmajid Larnaout; Rim Amouri; Sana Sfar; Samir Belal; Christiane Ben Hamida; Mongi Ben Hamida; Nobutaka Hattori; Yoshikuni Mizuno; Faycal Hentati
Autosomal recessive parkinsonism linked to parkin gene in a Tunisian family. Clinical, genetic and pathological study.
Parkinsonism & related disorders 2003;9(5):247-51.
2003: Rivka Inzelberg; Nobutaka Hattori; Puiu Nisipeanu; S Abo Mouch; Sergiu C Blumen; Ralph L Carasso; Yoshikuni Mizuno
Camptocormia, axial dystonia, and parkinsonism: phenotypic heterogeneity of a parkin mutation.
Neurology 2003;60(8):1393-4.
2003: Nina Rawal; Magali Periquet; Ebba Lohmann; Christoph B Lücking; Hélio A G Teive; G Ambrosio; Salmo Raskin; Sarah J Lincoln; Nobutaka Hattori; Joao Guimaraes; Martin Horstink; W Dos Santos Bele; E Brousolle; Alain Destée; Yoshikuni Mizuno; Matthew J Farrer; Jean-François Deleuze; Giuseppe De Michele; Yves Agid; Alexandra Dürr; Alexis Brice
New parkin mutations and atypical phenotypes in families with autosomal recessive parkinsonism.
Neurology 2003;60(8):1378-81.
2003: Shin-ichiro Ikebe; Toshiaki Harada; Takao Hashimoto; Ichiro Kanazawa; Sadako Kuno; Yoshikuni Mizuno; Eiji Mizuta; Miho Murata; Toshiharu Nagatsu; Shigenobu Nakamura; Hideki Takubo; Nobuo Yanagisawa; Hirotaro Narabayashi
Prevention and treatment of malignant syndrome in Parkinson's disease: a consensus statement of the malignant syndrome research group.
Parkinsonism & related disorders 2003;9 Suppl 1():S47-9.
2003: Hideki Takubo; Satoe Shimoda-Matsubayashi; Yoshikuni Mizuno
Serum creatine kinase is elevated in patients with Parkinson's disease: a case controlled study.
Parkinsonism & related disorders 2003;9 Suppl 1():S43-6.
2003: Hideki Takubo; Toshihide Harada; Takao Hashimoto; Yutaka Inaba; Ichiro Kanazawa; Sadako Kuno; Yoshikuni Mizuno; Eiji Mizuta; Miho Murata; Toshiharu Nagatsu; Shigenobu Nakamura; Nobuo Yanagisawa; Hirotaro Narabayashi
A collaborative study on the malignant syndrome in Parkinson's disease and related disorders.
Parkinsonism & related disorders 2003;9 Suppl 1():S31-41.
2003: Yoshikuni Mizuno; Hideki Takubo; Eiji Mizuta; Sadako Kuno
Malignant syndrome in Parkinson's disease: concept and review of the literature.
Parkinsonism & related disorders 2003;9 Suppl 1():S3-9.
2003: Hirotaro Narabayashi; Yoshikuni Mizuno
Preface: Malignant syndrome in Parkinson's disease.
Parkinsonism & related disorders 2003;9 Suppl 1():S1.
2003: Tsuyoshi Furuya; Ryota Tanaka; Takao Urabe; Jun Hayakawa; Makoto Migita; Takashi Shimada; Yoshikuni Mizuno; Hideki Mochizuki
Establishment of modified chimeric mice using GFP bone marrow as a model for neurological disorders.
Neuroreport 2003;14(4):629-31.
2003: Tomonori Kobayashi; Hiroto Matsumine; JiaLin Zhang; Yoko Imamichi; Yoshikuni Mizuno; Nobutaka Hattori
Pseudo-autosomal dominant inheritance of PARK2: two families with parkin gene mutations.
Journal of the neurological sciences 2003;207(1-2):11-7.
2003: Hideo Mori; Nobutaka Hattori; Yoshikuni Mizuno
Genotype-phenotype correlation: familial Parkinson disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2003;23(1):90-4.
2003: Eri Sakata; Yoshiki Yamaguchi; Eiji Kurimoto; Jun Kikuchi; Shigeyuki Yokoyama; Shingo Yamada; Hiroyuki Kawahara; Hideyoshi Yokosawa; Nobutaka Hattori; Yoshikuni Mizuno; Keiji Tanaka; Koichi Kato
Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin-like domain.
EMBO reports 2003;4(3):301-6.
2003: Yoshio Tsuboi; Zbigniew K Wszolek; Yoshikuni Mizuno; Tomonori Kobayashi; Minoru Yasuda; Tatsuo Yamada
[Japanese contribution to the understanding of frontotemporal dementia and parkinsonism linked to chromosome 17(FTDP-17)].
Nō to shinkei = Brain and nerve 2003;55(2):107-19.
2003: Hideki Mochizuki; Yoshikuni Mizuno
Gene therapy for Parkinson's disease.
Journal of neural transmission. Supplementum 2003;(65):205-13.
2003: Tsuyoshi Furuya; Tomoo Namihira; Shigetaka Yamazaki; Hideo Mori; Nobutaka Hattori; Yoshikuni Mizuno
[A 65-year-old woman with progressive loss of vision and visual field defects].
Nō to shinkei = Brain and nerve 2003;55(1):87-96.
2003: Ryota Tanaka; Miki Komine-Kobayashi; Hideki Mochizuki; Masanori Yamada; Tsuyoshi Furuya; Makoto Migita; Takashi Shimada; Yoshikuni Mizuno; Takao Urabe
Migration of enhanced green fluorescent protein expressing bone marrow-derived microglia/macrophage into the mouse brain following permanent focal ischemia.
Neuroscience 2003;117(3):531-9.
2003: Tomonori Kobayashi; Satoru Ota; Kuniaki Tanaka; Yuji Ito; Masato Hasegawa; Yuri Umeda; Yumiko Motoi; Masashi Takanashi; Masahiro Yasuhara; Midori Anno; Yoshikuni Mizuno; Hideo Mori
A novel L266V mutation of the tau gene causes frontotemporal dementia with a unique tau pathology.
Annals of neurology 2003;53(1):133-7.
2003: Hirokazu Kobayashi; Rejko Krüger; Katerina Markopoulou; Zbigniew K Wszolek; Bruce Chase; Hikari Taka; Reiko Mineki; Kimie Murayama; Olaf Riess; Yoshikuni Mizuno; Nobutaka Hattori
Haploinsufficiency at the alpha-synuclein gene underlies phenotypic severity in familial Parkinson's disease.
Brain : a journal of neurology 2003;126(Pt 1):32-42.
2002: Yoshio Tsuboi; Matt Baker; Michael Hutton; Ryan Uitti; Olivier Rascol; Marie-Bernadette Delisle; X Soulages; Jill R Murrell; Bernardino Ghetti; Minoru Yasuda; Osamu Komure; S Kuno; K Arima; N Sunohara; T Kobayashi; Yoshikuni Mizuno; Zbigniew K Wszolek
Clinical and genetic studies of families with the tau N279K mutation (FTDP-17).
Neurology 2002;59(11):1791-3.
2002: Tomoyoshi Kondo; Hideki Takubo; Fusako Yokochi; Yasuyuki Okuma; Yoshikuni Mizuno
[Long-term treatment of Parkinson's disease patients with selegiline hydrochloride (FPF 1100): outcome of 5-year treatment].
Nō to shinkei = Brain and nerve 2002;54(12):1041-8.
2002: Yasuyuki Okuma; Yoshikuni Mizuno
Absence of linkage to 8q24 in a European family with familial adult myoclonic epilepsy (FAME).
Neurology 2002;59(10):1665; author reply 1665-6.
2002: Masashi Tanaka; Noriyuki Fuku; Takeshi Takeyasu; Li-Jun Guo; Raita Hirose; Miyuki Kurata; Harm-Jan W Borgeld; Yoshiji Yamada; Wakako Maruyama; Yasumichi Arai; Nobuyoshi Hirose; Yoshiharu Oshida; Yuzo Sato; Nobutaka Hattori; Yoshikuni Mizuno; So Iwata; Kunio Yagi
Golden mean to longevity: rareness of mitochondrial cytochrome b variants in centenarians but not in patients with Parkinson's disease.
Journal of neuroscience research 2002;70(3):347-55.
2002: H Ohizumi; Yasuyuki Okuma; Jiro Fukae; Kenji Fujishima; K Goto; Yoshikuni Mizuno
Head tremor in dentatorubral-pallidoluysian atrophy.
Acta neurologica Scandinavica 2002;106(5):319-21.
2002: Motoyuki Hirasawa; Shin-ichiro Ikebe; Yasuko Komatsuzaki; Masashi Takanashi; Hideo Mori; Takao Urabe; Yoshikuni Mizuno
[A 52-year-old woman with dyskinesia, epilepsy and gait disturbance].
Nō to shinkei = Brain and nerve 2002;54(10):919-27.
2002: Atsuko Iroi; Yasuyuki Okuma; Jiro Fukae; Kenji Fujishima; Keigo Goto; Yoshikuni Mizuno
[Amyotrophic lateral sclerosis presented with alexia of kanji and word meaning aphasia].
Nō to shinkei = Brain and nerve 2002;54(10):903-7.
2002: Hideki Mochizuki; Masauki Miura; Takashi Shimada; Yoshikuni Mizuno
Adeno-associated virus-mediated antiapoptotic gene delivery: in vivo gene therapy for neurological disorders.
Methods (San Diego, Calif.) 2002;28(2):248-52.
2002: Hideto Miwa; Yoshikuni Mizuno
Enlargements of somatosensory-evoked potentials in progressive supranuclear palsy.
Acta neurologica Scandinavica 2002;106(4):209-12.
2002: Makiko Iijima; Yasuyuki Okuma; Hideki Ohizumi; Kenji Fujishima; Keigo Goto; Yoshikuni Mizuno
[A case of brachial plexus neuropathy who presented with acute paralysis of the hand after sleep].
Nō to shinkei = Brain and nerve 2002;54(9):819-22.
2002: Hideo Mori; Masaya Oda; Takashi Komori; Nobutaka Arai; Masashi Takanashi; Toshio Mizutani; Shunnichi Hirai; Yoshikuni Mizuno
Lewy bodies in progressive supranuclear palsy.
Acta neuropathologica 2002;104(3):273-8.
2002: Yves Agid; C Warren Olanow; Yoshikuni Mizuno
Levodopa: why the controversy?
Lancet 2002;360(9332):575.
2002: Masashi Takanashi; Hideo Mori; Kunimasa Arima; Yoshikuni Mizuno; Nobutaka Hattori
Expression patterns of tau mRNA isoforms correlate with susceptible lesions in progressive supranuclear palsy and corticobasal degeneration.
Brain research. Molecular brain research 2002;104(2):210-9.
2002: Yoshikuni Mizuno
[Progress in diagnosis and therapy for Parkinson's disease].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2002;91(8):2344-8.
2002: Dong-Hoon Hyun; MoonHee Lee; Nobutaka Hattori; Shin-Ichiro Kubo; Yoshikuni Mizuno; Barry Halliwell; Peter Jenner
Effect of wild-type or mutant Parkin on oxidative damage, nitric oxide, antioxidant defenses, and the proteasome.
The Journal of biological chemistry 2002;277(32):28572-7.
2002: Asuka Suzuki; K Obi; Takao Urabe; H Hayakawa; Masanori Yamada; S Kaneko; M Onodera; Yoshikuni Mizuno; Hideki Mochizuki
Feasibility of ex vivo gene therapy for neurological disorders using the new retroviral vector GCDNsap packaged in the vesicular stomatitis virus G protein.
Journal of neurochemistry 2002;82(4):953-60.
2002: Takao Urabe; Ryota Tanaka; Kazuyuki Noda; Yoshikuni Mizuno
Anticoagulant therapy with a selective thrombin inhibitor for acute cerebral infarction: usefulness of coagulation markers for evaluation of efficacy.
Journal of thrombosis and thrombolysis 2002;13(3):155-60.
2002: Tomonori Kobayashi; Hideo Mori; Yasuyuki Okuma; dennis dickson; Natalie Cookson; Yoshio Tsuboi; Yumiko Motoi; Ryota Tanaka; Nobuo Miyashita; Midori Anno; Hirotaro Narabayashi; Yoshikuni Mizuno
Contrasting genotypes of the tau gene in two phenotypically distinct patients with P301L mutation of frontotemporal dementia and parkinsonism linked to chromosome 17.
Journal of neurology 2002;249(6):669-75.
2002: Michael G Schlossmacher; Matthew P Frosch; Wei Ping Gai; Miguel Medina; Nutan Sharma; Lysia Forno; Tomoyo Ochiishi; Hideki Shimura; Ronit Sharon; Nobutaka Hattori; J William Langston; Yoshikuni Mizuno; Bradley T Hyman; Dennis J Selkoe; Kenneth S Kosik
Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies.
The American journal of pathology 2002;160(5):1655-67.
2002: Nobutaka Hattori; Yoshikuni Mizuno
[Mitochondrial dysfunction in Parkinson's disease].
Nihon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 4():406-11.
2002: Kenichi Sato; Nobutaka Hattori; Yoshikuni Mizuno
[Malignant migraine].
Nihon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 4():278-81.
2002: Yosuke Aoki; Takahiko Saida; Imaharu Nakano; Toyokazu Saito; Kunihiko Ikeguchi; Takao Urabe; Etsuko Nishiguchi; Hideaki Suzuki; Kiyoshi Takahashi; Yoshikuni Mizuno
[Determination of medullasin levels for the diagnosis of multiple sclerosis].
Rinsho byori. The Japanese journal of clinical pathology 2002;50(3):308-12.
2002: Ryota Tanaka; Hideki Mochizuki; Asuka Suzuki; Nobuo Katsube; Ryoichi Ishitani; Yoshikuni Mizuno; Takao Urabe
Induction of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) expression in rat brain after focal ischemia/reperfusion.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(3):280-8.
2002: Kazumasa Yokoyama; Shin-ichiro Ikebe; Yasuko Komatsuzaki; Masashi Takanashi; Hideo Mori; Hideki Mochizuki; Yoshikuni Mizuno
[A 68-year-old woman with dementia and parkinsonism].
Nō to shinkei = Brain and nerve 2002;54(2):175-84.
2002: Yasuyuki Okuma; Yoshikuni Mizuno; Robert G Lee
Reciprocal Ia inhibition in patients with asymmetric spinal spasticity.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2002;113(2):292-7.
2002: Masashi Takanashi; Satoshi Ohta; Shuji Matsuoka; Hideo Mori; Yoshikuni Mizuno
Mixed multiple system atrophy and progressive supranuclear palsy: a clinical and pathological report of one case.
Acta neuropathologica 2002;103(1):82-7.
2001: A Suzuki; Hideki Mochizuki; Y Kajiyama; M Kimura; T Furukawa; Ginichirou Ichikawa; Heii Arai; Yoshikuni Mizuno
[A case of convergence spasm in hysteria improved with a brief psychiatric assessment].
Nō to shinkei = Brain and nerve 2001;53(12):1141-4.
2001: Jiro Fukae; Yasuyuki Okuma; Kazuyuki Noda; Kenji Fujishima; Keigo Goto; Yoshikuni Mizuno
[A quadriplegic patient with chronic inflammatory demyelinating polyneuropathy (CIDP) who responded well to corticosteroids and intravenous immunoglobulin therapy].
Nō to shinkei = Brain and nerve 2001;53(12):1115-8.
2001: Kazuo Yamashiro; Hideo Mori; A Suzuki; Kiyoshi L Mori; Y Hamano; Yoshikuni Mizuno
[A patient with intravascular malignant lymphomatosis presenting subacute dementia one year after sustained urinary retention and high serum LDH activity from the onset].
Rinshō shinkeigaku = Clinical neurology 2001;41(11):784-91.
2001: A Suzuki; Shin-ichiro Ikebe; Yasuko Komatsuzaki; Masashi Takanashi; Hideo Mori; Nobutaka Hattori; Yoshikuni Mizuno
[A 64-year-old man with parkinsonism as an initial symptom followed by dementia associated with marked abnormal behaviours].
Nō to shinkei = Brain and nerve 2001;53(11):1075-87.
2001: Hideki Mochizuki; Hideki Hayakawa; Makoto Migita; M Shibata; Ryota Tanaka; Asuka Suzuki; Yumi Shimo-Nakanishi; Takao Urabe; Masanori Yamada; Kenji Tamayose; Takashi Shimada; Masayuki Miura; Yoshikuni Mizuno
An AAV-derived Apaf-1 dominant negative inhibitor prevents MPTP toxicity as antiapoptotic gene therapy for Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(19):10918-23.
2001: Keiichi Tanaka; T Suzuki; Tsutomu Chiba; H Shimura; Nobutaka Hattori; Yoshikuni Mizuno
Parkin is linked to the ubiquitin pathway.
Journal of molecular medicine (Berlin, Germany) 2001;79(9):482-94.
2001: H Miwa; Yoshikuni Mizuno
Capgras syndrome in Parkinson's disease.
Journal of neurology 2001;248(9):804-5.
2001: Hideo Mori; Yumiko Motoi; Tomonori Kobayashi; Masato Hasegawa; A Yamamura; Takeshi Iwatsubo; Yoshikuni Mizuno
Tau accumulation in a patient with pallidonigroluysian atrophy.
Neuroscience letters 2001;309(2):89-92.
2001: Yoshikuni Mizuno; Nobutaka Hattori; Hideo Mori; T Suzuki; Keiji Tanaka
Parkin and Parkinson's disease.
Current opinion in neurology 2001;14(4):477-82.
2001: Kazuyuki Noda; Yasuyuki Okuma; Jiro Fukae; Kenji Fujishima; Keigo Goto; H Sadamasa; T Yoshiike; Yoshikuni Mizuno
Sweet's syndrome associated with encephalitis.
Journal of the neurological sciences 2001;188(1-2):95-7.
2001: Hideki Shimura; Michael G Schlossmacher; Nobutaka Hattori; Matthew P Frosch; A Trockenbacher; R Schneider; Yoshikuni Mizuno; Kenneth S Kosik; Dennis J Selkoe
Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease.
Science (New York, N.Y.) 2001;293(5528):263-9.
2001: Yumi Shimo-Nakanishi; Takao Urabe; Nobutaka Hattori; Yoshiro Watanabe; T Nagao; Masayuki Yokochi; Makoto Hamamoto; Yoshikuni Mizuno
Polymorphism of the lipoprotein lipase gene and risk of atherothrombotic cerebral infarction in the Japanese.
Stroke; a journal of cerebral circulation 2001;32(7):1481-6.
2001: S i Kubo; Toshiaki Kitami; S Noda; Hideki Shimura; Yasuo Uchiyama; Shuichi Asakawa; Shinsei Minoshima; Nobuyoshi Shimizu; Yoshikuni Mizuno; Nobutaka Hattori
Parkin is associated with cellular vesicles.
Journal of neurochemistry 2001;78(1):42-54.
2001: Yuzuru Imai; Mariko Soda; Haruhisa Inoue; Nobutaka Hattori; Yoshikuni Mizuno; Ryosuke Takahashi
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin.
Cell 2001;105(7):891-902.
2001: Puiu Nisipeanu; Rivka Inzelberg; S Abo Mouch; Ralph L Carasso; Sergiu C Blumen; J Zhang; H Matsumine; Nobutaka Hattori; Yoshikuni Mizuno
Parkin gene causing benign autosomal recessive juvenile parkinsonism.
Neurology 2001;56(11):1573-5.
2001: R Tanaka; Tomonori Kobayashi; Masashi Takanashi; Hiroyuki Tadokoro; Hideo Mori; Koichi Suda; Akira Kanazawa; Yoshikuni Mizuno
[A 68-year-old man with speech disturbance as the initial symptom followed by bradykinesia and dementia. Clinical conference].
Nō to shinkei = Brain and nerve 2001;53(6):585-97.
2001: Y Sasaki; Hideki Takubo; T Arai; Y Machida; Shin-ichiro Ikebe; N Yuki; Yoshikuni Mizuno
[Atypical Fisher syndrome with optic nerve involvement].
Nō to shinkei = Brain and nerve 2001;53(6):571-3.
2001: M Wang; T Suzuki; Tohru Kitada; Shuichi Asakawa; Shinsei Minoshima; Nobuyoshi Shimizu; Keiji Tanaka; Yoshikuni Mizuno; Nobutaka Hattori
Developmental changes in the expression of parkin and UbcR7, a parkin-interacting and ubiquitin-conjugating enzyme, in rat brain.
Journal of neurochemistry 2001;77(6):1561-8.
2001: B S Jeon; J M Kim; D S Lee; Nobutaka Hattori; Yoshikuni Mizuno
An apparently sporadic case with parkin gene mutation in a Korean woman.
Archives of neurology 2001;58(6):988-9.
2001: Yasuji Shimo; Masashi Takanashi; Satoshi Ohta; K Terashima; Hideo Mori; T Shirai; Hideto Miwa; Yoshikuni Mizuno
[A-56-year-old woman with parkinsonism, whose mother had Parkinson's disease].
Nō to shinkei = Brain and nerve 2001;53(5):495-505.
2001: Akira Kanazawa; Yoshikuni Mizuno; Hirotaro Narabayashi
[Executive function in Parkinson's disease].
Rinshō shinkeigaku = Clinical neurology 2001;41(4-5):167-72.
2001: Makio Mogi; Akifumi Togari; T Kondo; Yoshikuni Mizuno; O Kogure; S Kuno; H Ichinose; Toshiharu Nagatsu
Glial cell line-derived neurotrophic factor in the substantia nigra from control and parkinsonian brains.
Neuroscience letters 2001;300(3):179-81.
2001: Tsuyoshi Furuya; Hideto Miwa; Taku Hatano; N Miyashita; Shigeki Tanaka; Yoshikuni Mizuno
[Clinical features of myelitis in patients with atopic symptoms].
Nō to shinkei = Brain and nerve 2001;53(3):241-5.
2001: Y Okuma; Yoshikuni Mizuno
Myoclonic tremor in patients with parkinsonian-type multiple system atrophy.
Movement disorders : official journal of the Movement Disorder Society 2001;16(2):378-9.
2001: Akira Kanazawa; Shin-ichiro Ikebe; Yasuko Komatsuzaki; Masashi Takanashi; Hideo Mori; Hideki Mochizuki; Yoshikuni Mizuno
[An 84-year-old woman with progressive mental deterioration and abnormal behavior].
Nō to shinkei = Brain and nerve 2001;53(2):199-209.
2001: C Nohara; Hisaya Akiba; Atsuo Nakajima; A Inoue; C S Koh; H Ohshima; Hideo Yagita; Yoshikuni Mizuno; Ko Okumura
Amelioration of experimental autoimmune encephalomyelitis with anti-OX40 ligand monoclonal antibody: a critical role for OX40 ligand in migration, but not development, of pathogenic T cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(3):2108-15.
2001: Hiroto Matsumine; Nobutaka Hattori; Yoshikuni Mizuno
Autosomal Recessive Juvenile Parkinsonism (AR-JP): Genetic Diagnosis.
Methods in molecular medicine 2001;62():13-29.
2001: Yoshikuni Mizuno; Nobutaka Hattori; Tohru Kitada; Hiroto Matsumine; Hideo Mori; Hideki Shimura; S i Kubo; Hirokazu Kobayashi; Shuichi Asakawa; Shinsei Minoshima; Nobuyoshi Shimizu
Familial Parkinson's disease. Alpha-synuclein and parkin.
Advances in neurology 2001;86():13-21.
2001: Yasuyuki Okuma; Kenji Fujishima; Y Machida; N Inagaki; Y Sugita; Yoshikuni Mizuno
Propriospinal negative myoclonus.
European neurology 2001;46(2):99-101.
2001: H Miwa; T Furuya; S Tanaka; Yoshikuni Mizuno
Neurosarcoidosis associated with interferon therapy.
European neurology 2001;45(4):288-9.
2001: Yasuyuki Okuma; R Tanaka; Kenji Fujishima; T Kobayashi; Yoshikuni Mizuno
Cortical reflex action myoclonus in neurosyphilis.
European neurology 2001;45(3):193-4.
2001: Chin-Song Lu; J C Wu; C H Tsai; Rou-Shayn Chen; Y H Chou; Nobutaka Hattori; H Yoshino; Yoshikuni Mizuno
Clinical and genetic studies on familial parkinsonism: the first report on a parkin gene mutation in a Taiwanese family.
Movement disorders : official journal of the Movement Disorder Society 2001;16(1):164-6.
2000: Nobutaka Hattori; H Shimura; S Kubo; T Suzuki; K Tanaka; Yoshikuni Mizuno
[Autosomal recessive juvenile parkinsonism: its pathogenesis is involved in the ubiquitin-proteasome pathway].
Rinshō shinkeigaku = Clinical neurology 2000;40(12):1293-6.
2000: Taku Hatano; Hideto Miwa; Tsuyoshi Furuya; N Miyashita; Shigeki Tanaka; Yoshikuni Mizuno
[Anosognosia for hemiplegia in a patient with pontine infarction].
Nō to shinkei = Brain and nerve 2000;52(12):1117-20.
2000: S Kubo; T Hattori; Masashi Takanashi; Hideo Mori; Y Mizutani; Koichi Suda; Nobutaka Hattori; Yoshikuni Mizuno
[A 57-year-old woman with progressive disturbance of gait and mental deterioration].
Nō to shinkei = Brain and nerve 2000;52(11):1035-44.
2000: Yasuyuki Okuma; Takao Urabe; Hideki Mochizuki; Hideto Miwa; Yasuji Shimo; Hideo Mori; Yoshikuni Mizuno
Asymmetric cortico-cortical inhibition in patients with progressive limb-kinetic apraxia.
Acta neurologica Scandinavica 2000;102(4):244-8.
2000: T Ishiwata; A Suzuki; Hideki Mochizuki; Yasuyuki Okuma; K Mitani; Yoshikuni Mizuno
[Progressive limb-kinetic apraxia with myoclonus focal atrophy in the postcentral gyrus and the supplementary motor area].
Nō to shinkei = Brain and nerve 2000;52(10):925-8.
2000: Tohru Kitada; Yoshikuni Mizuno
[Molecular pathogenesis of familial Parkinson's disease].
Nihon rinsho. Japanese journal of clinical medicine 2000;58(10):2016-21.
2000: Yoshikuni Mizuno; Nobutaka Hattori
[Progress in studies of Parkinson's disease].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2000;89(9):1970-6.
2000: Ryota Tanaka; Tomonori Kobayashi; Yumiko Motoi; Midori Anno; Yoshikuni Mizuno; Hideo Mori
A case of frontotemporal dementia with tau P301L mutation in the Far East.
Journal of neurology 2000;247(9):705-7.
2000: Nobutaka Hattori; Hideki Shimura; S i Kubo; Tohru Kitada; M Wang; Shuichi Asakawa; S Minashima; Nobuyoshi Shimizu; T Suzuki; Keiji Tanaka; Yoshikuni Mizuno
Autosomal recessive juvenile parkinsonism: a key to understanding nigral degeneration in sporadic Parkinson's disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2000;20 Suppl():S85-90.
2000: Yasuhiro Yamamura; Nobutaka Hattori; H Matsumine; S Kuzuhara; Yoshikuni Mizuno
Autosomal recessive early-onset parkinsonism with diurnal fluctuation: clinicopathologic characteristics and molecular genetic identification.
Brain & development 2000;22 Suppl 1():S87-91.
2000: T Yamamoto; K Goto; A Suzuki; N Nakamura; Yoshikuni Mizuno
Long-term improvement of idiopathic hypertrophic cranial pachymeningitis by lymphocytapheresis.
Therapeutic apheresis : official journal of the International Society for Apheresis and the Japanese Society for Apheresis 2000;4(4):313-6.
2000: Kiyoshi Sato; S Sato; Satoshi Ohta; Hideo Mori; Shuji Matsuoka; T Shirai; A Kanazaea; Yoshikuni Mizuno
[A 67-year-old man with progressive disturbance of gait].
Nō to shinkei = Brain and nerve 2000;52(7):643-53.
2000: Hideki Shimura; Nobutaka Hattori; S i Kubo; Yoshikuni Mizuno; Shuichi Asakawa; Shinsei Minoshima; Nobuyoshi Shimizu; K Iwai; Tomoki Chiba; Keiji Tanaka; T Suzuki
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase.
Nature genetics 2000;25(3):302-5.
2000: Tohru Kitada; Shuichi Asakawa; Shinsei Minoshima; Yoshikuni Mizuno; Nobuyoshi Shimizu
Molecular cloning, gene expression, and identification of a splicing variant of the mouse parkin gene.
Mammalian genome : official journal of the International Mammalian Genome Society 2000;11(6):417-21.
2000: Tohru Kitada; Shuichi Asakawa; Hiroto Matsumine; Nobutaka Hattori; Hideki Shimura; Shinsei Minoshima; Nobuyoshi Shimizu; Yoshikuni Mizuno
Progress in the clinical and molecular genetics of familial parkinsonism.
Neurogenetics 2000;2(4):207-18.
2000: Teruhiko Sato; Kazuhisa Takahashi; Yasuyuki Okuma; Yoshikuni Mizuno; Kensho Noto; Masaharu Katae; Takashi Dambara; Yoshinosuke Fukuchi
[A senile case of acute necrotizing myopathy presenting prolonged severe muscle paralysis due to high dose glucocorticoid and muscle relaxant].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 2000;37(3):250-4.
2000: Shin-ichiro Ikebe; Hideo Mori; S Sumino; Masashi Takanashi; Y Hamano; T Shirai; Y Ohkuma; Yoshikuni Mizuno
[A 77-year-old man with gait and gaze disturbance].
Nō to shinkei = Brain and nerve 2000;52(3):269-79.
2000: A Iroi; N Miyashita; S Nakamura; H Ohizumi; Yoshikuni Mizuno
[A patient with marked immunodeficiency in an HTLV-I carrier: a case report].
Rinshō shinkeigaku = Clinical neurology 2000;40(2):135-9.
2000: Nobutaka Hattori; Hideki Shimura; S i Kubo; M Wang; Nobuyoshi Shimizu; Keiji Tanaka; Yoshikuni Mizuno
Importance of familial Parkinson's disease and parkinsonism to the understanding of nigral degeneration in sporadic Parkinson's disease.
Journal of neural transmission. Supplementum 2000;(60):101-16.
2000: Nobuyoshi Shimizu; Shuichi Asakawa; Shinsei Minoshima; Tohru Kitada; Nobutaka Hattori; Hiroto Matsumine; Masayuki Yokochi; Yasuhiro Yamamura; Yoshikuni Mizuno
PARKIN as a pathogenic gene for autosomal recessive juvenile parkinsonism.
Journal of neural transmission. Supplementum 2000;(58):19-30.
2000: Takao Urabe; Y Yamasaki; Nobutaka Hattori; M Yoshikawa; K Uchida; Yoshikuni Mizuno
Accumulation of 4-hydroxynonenal-modified proteins in hippocampal CA1 pyramidal neurons precedes delayed neuronal damage in the gerbil brain.
Neuroscience 2000;100(2):241-50.
2000: Makio Mogi; Akifumi Togari; T Kondo; Yoshikuni Mizuno; O Komure; S Kuno; H Ichinose; Toshiharu Nagatsu
Caspase activities and tumor necrosis factor receptor R1 (p55) level are elevated in the substantia nigra from parkinsonian brain.
Journal of neural transmission (Vienna, Austria : 1996) 2000;107(3):335-41.
2000: Y Sasaki; Hideto Miwa; Jiro Fukae; Kozo Hatori; Shigeki Tanaka; Yoshikuni Mizuno
[Transient improvement in motor function and hemineglect by vestibular stimulation in a patient with right middle cerebral artery embolism].
Nō to shinkei = Brain and nerve 2000;52(1):49-52.
1999: Tohru Kitada; Shuichi Asakawa; Hiroto Matsumine; Nobutaka Hattori; Shinsei Minoshima; Nobuyoshi Shimizu; Yoshikuni Mizuno
Positional cloning of the autosomal recessive juvenile parkinsonism (AR-JP) gene and its diversity in deletion mutations.
Parkinsonism & related disorders 1999;5(4):163-8.
1999: Nobutaka Hattori; Yoshikuni Mizuno
[Parkin gene and its function; a key to understand nigral degeneration].
Rinshō shinkeigaku = Clinical neurology 1999;39(12):1259-61.
1999: Masashi Takanashi; Takao Urabe; Satoshi Ohta; Y Hamano; Hideo Mori; T Shirai; Tomoyoshi Kondo; Yoshikuni Mizuno
[A 73-year-old woman with familial Parkinson's disease].
Nō to shinkei = Brain and nerve 1999;51(12):1087-96.
1999: A Iroi; Hideto Miwa; M Iijima; Jiro Fukae; Kozo Hatori; Shigeki Tanaka; T Yano; Yoshikuni Mizuno
[The dissecting aortic aneurysm associated with polymyalgia rheumatica: a case report].
Nō to shinkei = Brain and nerve 1999;51(12):1051-4.
1999: Terubumi Watanabe; Hideto Miwa; Keiichiro Wada; K Sugano; Kozo Hatori; Shigeki Tanaka; Yoshikuni Mizuno
[Rhythmic involuntary movement of the neck in a patient with brainstem encephalitis].
Nō to shinkei = Brain and nerve 1999;51(12):1045-8.
1999: Yasuyuki Okuma; K Ohi; R G Lee; Yoshikuni Mizuno
Effects of test H-reflex size on reciprocal inhibition in forearm muscles.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 1999;110(12):2194-6.
1999: H Shimura-Miura; Nobutaka Hattori; D Kang; K Miyako; Yusaku Nakabeppu; Yoshikuni Mizuno
Increased 8-oxo-dGTPase in the mitochondria of substantia nigral neurons in Parkinson's disease.
Annals of neurology 1999;46(6):920-4.
1999: H Narabayashi; T Yamaguchi; K Sugi; H Mitamura; Yoshikuni Mizuno; M Nakashima
Safety study of lazabemide (Ro19-6327), a new MAO-B inhibitor, on cardiac arrhythmias and blood pressure of patients with Parkinson's disease.
Clinical neuropharmacology 1999;22(6):340-6.
1999: Yves Agid; E Ahlskog; A Albanese; Donald B Calne; Thomas N Chase; J De Yebenes; Stewart A Factor; Stanley Fahn; Oscar S Gershanik; Christopher G Goetz; William Koller; M Kurth; Anthony E Lang; Andrew J Lees; Peter LeWitt; D Marsden; Eldad Melamed; Patrick P Michel; Yoshikuni Mizuno; Jose A Obeso; Wolfgang H Oertel; W Olanow; Werner Poewe; Pierre Pollak; Eduardo Tolosa
Levodopa in the treatment of Parkinson's disease: a consensus meeting.
Movement disorders : official journal of the Movement Disorder Society 1999;14(6):911-3.
1999: Puiu Nisipeanu; Rivka Inzelberg; Sergiu C Blumen; Ralph L Carasso; Nobutaka Hattori; H Matsumine; Yoshikuni Mizuno
Autosomal-recessive juvenile parkinsonism in a Jewish Yemenite kindred: mutation of Parkin gene.
Neurology 1999;53(7):1602-4.
1999: K Torizuka; Yoshikuni Mizuno; A Kubo; Junji Konishi; Yoshiharu Yonekura; J Hatazawa; T Momose; M Murata; T Amano; Hidenao Fukuyama; Y Kuwabara
[Phase 2 clinical study of 123I-IBF, a dopamine D2 receptor imaging agent, to evaluate clinical efficacy and safety in Parkinson's disease and Parkinson syndromes].
Kaku igaku. The Japanese journal of nuclear medicine 1999;36(8):845-64.
1999: Hideto Miwa; Y Sasaki; Kozo Hatori; Shigeki Tanaka; Yoshikuni Mizuno
[Idiopathic rabbit syndrome: a case report].
Nō to shinkei = Brain and nerve 1999;51(10):907-9.
1999: Makio Mogi; Akifumi Togari; T Kondo; Yoshikuni Mizuno; O Komure; S Kuno; H Ichinose; Toshiharu Nagatsu
Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease.
Neuroscience letters 1999;270(1):45-8.
1999: Nobutaka Hattori; S Sumino; Masashi Takanashi; Hideo Mori; M Wakiya; T Shirai; H Sugita; Yoshikuni Mizuno
[An 80-year-old woman with parkinsonism and progressive dementia].
Nō to shinkei = Brain and nerve 1999;51(6):541-50.
1999: Nobutaka Hattori; Yoshikuni Mizuno
[The Parkin gene and its product in AR-JP].
Nō to shinkei = Brain and nerve 1999;51(6):493-500.
1999: Yumi Shimo-Nakanishi; Hideto Miwa; Hirokazu Kobayashi; H Oshima; S Nakamura; Takao Urabe; Yoshikuni Mizuno
[Primary progressive limb-kinetic apraxia: a case report with an electrophysiological study].
Nō to shinkei = Brain and nerve 1999;51(5):439-43.
1999: Hideki Shimura; Nobutaka Hattori; S i Kubo; M Yoshikawa; Tohru Kitada; Hiroto Matsumine; Shuichi Asakawa; Shinsei Minoshima; Yasuhiro Yamamura; Nobuyoshi Shimizu; Yoshikuni Mizuno
Immunohistochemical and subcellular localization of Parkin protein: absence of protein in autosomal recessive juvenile parkinsonism patients.
Annals of neurology 1999;45(5):668-72.
1999: M Wang; Nobutaka Hattori; Hiroto Matsumine; Tomonori Kobayashi; Hiroyo Yoshino; A Morioka; Tohru Kitada; Shuichi Asakawa; Shinsei Minoshima; Nobuyoshi Shimizu; Yoshikuni Mizuno
Polymorphism in the parkin gene in sporadic Parkinson's disease.
Annals of neurology 1999;45(5):655-8.
1999: K Sugano; K Goto; K Hatori; T Hattori; H Miwa; Shigeki Tanaka; Yoshikuni Mizuno
[Clinical and neuroradiological features of spontaneous intracranial hypotension: report of two cases].
Nō to shinkei = Brain and nerve 1999;51(4):345-8.
1999: Hideto Miwa; Tomoyoshi Kondo; Yoshikuni Mizuno
[Striatonigral degeneration and sporadic olivopontocerebellar atrophy: a consideration of the clinical entity of multiple system atrophy].
Nō to shinkei = Brain and nerve 1999;51(4):305-12.
1999: Yoshikuni Mizuno; Nobutaka Hattori; Hideo Mori
Genetics of Parkinson's disease.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 1999;53(3):109-16.
1999: A Yoritaka; Y Nakagawa-Hattori; Nobutaka Hattori; A Kitahara; Yoshikuni Mizuno
A large Japanese family with Machado-Joseph disease: clinical and genetic analysis.
Acta neurologica Scandinavica 1999;99(4):241-4.
1999: Etienne C Hirsch; Stéphane Hunot; Baptiste A Faucheux; Yves Agid; Yoshikuni Mizuno; H Mochizuki; William G Tatton; Nadine A Tatton; W C Olanow
Dopaminergic neurons degenerate by apoptosis in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 1999;14(2):383-5.
1999: Hideto Miwa; A Yoritaka; Yoshikuni Mizuno
Hemifacial spasm in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 1999;14(2):358-9.
1999: T Hattori; Shigeki Tanaka; Yasuji Shimo; Midori Anno; Satoshi Ohta; Kazuhisa Ishi; Hideo Mori; Y Ohkuma; Yoshikuni Mizuno
[A 40-year-old woman with progressive dementia and abnormal behavior].
Nō to shinkei = Brain and nerve 1999;51(2):185-94.
1999: Hiroto Matsumine; M Saito; A Ishikawa; Masayuki Yokochi; Yasuhiro Yamamura; Shoji Tsuji; Yoshikuni Mizuno
Dopamine cell death by a single genetic mechanism: phenotypic analysis and linkage study of autosomal recessive juvenile parkinsonism.
Advances in neurology 1999;80():187-94.
1999: Yoshikuni Mizuno; S Shimoda-Matsubayashi; Hiroto Matsumine; N Morikawa; Nobutaka Hattori; Tomoyoshi Kondo
Genetic and environmental factors in the pathogenesis of Parkinson's disease.
Advances in neurology 1999;80():171-9.
1999: Akira Kanazawa; Kazuyuki Noda; H Suzuki; Satoshi Ohta; Hideo Mori; Koichi Suda; Hideki Takubo; Yoshikuni Mizuno
[A 96-year-old man with consciousness disturbance, convulsion, and left hemiplegia of acute onset].
Nō to shinkei = Brain and nerve 1999;51(1):83-93.
1998: Nobutaka Hattori; Tohru Kitada; Hiroto Matsumine; Shuichi Asakawa; Yasuhiro Yamamura; Hiroyo Yoshino; Tomonori Kobayashi; Masayuki Yokochi; M Wang; A Yoritaka; Tomoyoshi Kondo; S Kuzuhara; S Nakamura; Nobuyoshi Shimizu; Yoshikuni Mizuno
Molecular genetic analysis of a novel Parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: evidence for variable homozygous deletions in the Parkin gene in affected individuals.
Annals of neurology 1998;44(6):935-41.
1998: N Miyashita; Tomoyoshi Kondo; M Wakiya; Hideo Mori; T Shirai; Hideki Takubo; Yoshikuni Mizuno
[A 61-year-old man with progressive gait disturbance, freezing, and vertical gaze paresis who developed esophagus cancer].
Nō to shinkei = Brain and nerve 1998;50(11):1041-52.
1998: Y Sugita; Hiroto Matsumine; M Wakiya; Hideo Mori; Koichi Suda; Tomoyoshi Kondo; Yoshikuni Mizuno
[A 64-year-old woman with progressive gait disturbance and dementia for one year].
Nō to shinkei = Brain and nerve 1998;50(9):861-70.
1998: Yoshikuni Mizuno; Hiroyo Yoshino; Shin-ichiro Ikebe; Nobutaka Hattori; Tomonori Kobayashi; S Shimoda-Matsubayashi; Hiroto Matsumine; Tomoyoshi Kondo
Mitochondrial dysfunction in Parkinson's disease.
Annals of neurology 1998;44(3 Suppl 1):S99-109.
1998: Hideo Mori; Tomoyoshi Kondo; Masayuki Yokochi; Hiroto Matsumine; Y Nakagawa-Hattori; T Miyake; K Suda; Yoshikuni Mizuno
Pathologic and biochemical studies of juvenile parkinsonism linked to chromosome 6q.
Neurology 1998;51(3):890-2.
1998: Yoshikuni Mizuno; Nobutaka Hattori; Hiroto Matsumine
Neurochemical and neurogenetic correlates of Parkinson's disease.
Journal of neurochemistry 1998;71(3):893-902.
1998: Nobutaka Hattori; Hiroto Matsumine; Shuichi Asakawa; Tohru Kitada; Hiroyo Yoshino; B Elibol; A J Brookes; Yasuhiro Yamamura; Tomonori Kobayashi; M Wang; A Yoritaka; Shinsei Minoshima; Nobuyoshi Shimizu; Yoshikuni Mizuno
Point mutations (Thr240Arg and Gln311Stop) [correction of Thr240Arg and Ala311Stop] in the Parkin gene.
Biochemical and biophysical research communications 1998;249(3):754-8.
1998: Yasuhiro Yamamura; S Kuzuhara; K Kondo; T Yanagi; M Uchida; H Matsumine; Yoshikuni Mizuno
Clinical, pathologic and genetic studies on autosomal recessive early-onset parkinsonism with diurnal fluctuation.
Parkinsonism & related disorders 1998;4(2):65-72.
1998: Yoshikuni Mizuno
Second International Symposium on the Treatment of Parkinson's Disease.
Neurology 1998;51(2 Suppl 2):S1.
1998: Yasuyuki Okuma; Nobutaka Hattori; Bunsei Nobukawa; Hideo Mori; Koichi Suda; Hideki Takubo; Yoshikuni Mizuno
[A 74-year-old woman with parkinsonism and dementia who died four years after the onset].
Nō to shinkei = Brain and nerve 1998;50(7):671-82.
1998: T Urabe; Nobutaka Hattori; M Yoshikawa; H Yoshino; K Uchida; Yoshikuni Mizuno
Colocalization of Bcl-2 and 4-hydroxynonenal modified proteins in microglial cells and neurons of rat brain following transient focal ischemia.
Neuroscience letters 1998;247(2-3):159-62.
1998: Tomoyoshi Kondo; H Shimada; Kozo Hatori; Y Sugita; Yoshikuni Mizuno
Talipexole protects dopaminergic neurons from methamphetamine toxicity in C57BL/6N mouse.
Neuroscience letters 1998;247(2-3):143-6.
1998: Hideki Takubo; Nobutaka Hattori; S Irie; Y Mizutani; Hideo Mori; Koichi Suda; Tomoyoshi Kondo; K Oshimi; Yoshikuni Mizuno
[A 45-year-old man with peripheral monocytosis and right hemiparesis].
Nō to shinkei = Brain and nerve 1998;50(5):481-9.
1998: Hiroto Matsumine; Yasuhiro Yamamura; Tomonori Kobayashi; S Nakamura; S Kuzuhara; Yoshikuni Mizuno
Early onset parkinsonism with diurnal fluctuation maps to a locus for juvenile parkinsonism.
Neurology 1998;50(5):1340-5.
1998: Tohru Kitada; Shuichi Asakawa; Nobutaka Hattori; Hiroto Matsumine; Yasuhiro Yamamura; Shinsei Minoshima; Masayuki Yokochi; Yoshikuni Mizuno; Nobuyoshi Shimizu
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism.
Nature 1998;392(6676):605-8.
1998: Yasuji Shimo; C Nohara; M Hotta; Hideto Miwa; Yoshikuni Mizuno
[Superficial siderosis of the central nervous system: an electrophysiological study].
Nō to shinkei = Brain and nerve 1998;50(4):361-5.
1998: Hiroto Matsumine; Yasuhiro Yamamura; Nobutaka Hattori; Tomonori Kobayashi; Tohru Kitada; A Yoritaka; Yoshikuni Mizuno
A microdeletion of D6S305 in a family of autosomal recessive juvenile parkinsonism (PARK2).
Genomics 1998;49(1):143-6.
1998: Nobutaka Hattori; Hiroyo Yoshino; M Tanaka; H Suzuki; Yoshikuni Mizuno
Genotype in the 24-kDa subunit gene (NDUFV2) of mitochondrial complex I and susceptibility to Parkinson disease.
Genomics 1998;49(1):52-8.
1998: S Sato; Nobutaka Hattori; Hiroto Matsumine; H Imai; Yoshikuni Mizuno
[A patient with focal bi-parietal atrophy presenting motor clumsiness and cortical sensory loss].
Rinshō shinkeigaku = Clinical neurology 1998;38(3):246-51.
1998: Yasuyuki Okuma; Yasuji Shimo; H Shimura; Kozo Hatori; T Hattori; Shigeki Tanaka; Tomoyoshi Kondo; Yoshikuni Mizuno
Familial cortical tremor with epilepsy: an under-recognized familial tremor.
Clinical neurology and neurosurgery 1998;100(1):75-8.
1998: Takao Urabe; Hideo Mori; S Sumino; Hideto Miwa; M Wakiya; T Shirai; Hideki Takubo; Yoshikuni Mizuno
[An 81-year-old woman with progressive motor disturbance, extrapyramidal features, dementia, and oculomotor palsy].
Nō to shinkei = Brain and nerve 1998;50(3):291-301.
1998: Yoshikuni Mizuno; H Mochizuki; Y Sugita; K Goto
Apoptosis in neurodegenerative disorders.
Internal medicine (Tokyo, Japan) 1998;37(2):192-3.
1998: Hideto Miwa; I Koshimura; Yoshikuni Mizuno
Recurrent cranial neuropathy as a clinical presentation of idiopathic inflammation of the dura mater: a possible relationship to Tolosa-Hunt syndrome and cranial pachymeningitis.
Journal of the neurological sciences 1998;154(1):101-5.
1998: N Morikawa; Makoto Naoi; Wakako Maruyama; S Ohta; Y Kotake; H Kawai; T Niwa; P Dostert; Yoshikuni Mizuno
Effects of various tetrahydroisoquinoline derivatives on mitochondrial respiration and the electron transfer complexes.
Journal of neural transmission (Vienna, Austria : 1996) 1998;105(6-7):677-88.
1998: M Saito; Hiroto Matsumine; Hajime Tanaka; A Ishikawa; S Shimoda-Matsubayashi; A A Schäffer; Yoshikuni Mizuno; Shoji Tsuji
Refinement of the gene locus for autosomal recessive juvenile parkinsonism (AR-JP) on chromosome 6q25.2-27 and identification of markers exhibiting linkage disequilibrium.
Journal of human genetics 1998;43(1):22-31.
1998: Y Motoi; K Satoh; Hiroto Matsumine; M Wakiya; Hideo Mori; T Shirai; Tomoyoshi Kondo; Yoshikuni Mizuno
[A 49-year-old man with progressive bulbar palsy and respiratory failure].
Nō to shinkei = Brain and nerve 1998;50(1):93-100.
1998: Tomonori Kobayashi; Hiroto Matsumine; S Matuda; Yoshikuni Mizuno
Association between the gene encoding the E2 subunit of the alpha-ketoglutarate dehydrogenase complex and Parkinson's disease.
Annals of neurology 1998;43(1):120-3.
1997: I Koshimura; H Sugita; Kiyoshi Sato; H Suzuki; Hideo Mori; Koichi Suda; Hideki Takubo; Yoshikuni Mizuno
[A 62-year-old man with an acute onset of consciousness disturbances].
Nō to shinkei = Brain and nerve 1997;49(12):1161-70.
1997: C Nohara; Hiroto Matsumine; K Suzuki; A Saito; M Ohtaka; Hideo Mori; Koichi Suda; Tomoyoshi Kondo; M Hayakawa; J Kanai; Yoshikuni Mizuno
[(Neurological CPC-59). A 65-year-old man with a history of gastric cancer who presented progressive loss of vision, memory loss and consciousness disturbance].
Nō to shinkei = Brain and nerve 1997;49(11):1041-51.
1997: S Shimoda-Matsubayashi; T Hattori; Hiroto Matsumine; A Shinohara; A Yoritaka; Hideo Mori; Tomoyoshi Kondo; M Chiba; Yoshikuni Mizuno
Mn SOD activity and protein in a patient with chromosome 6-linked autosomal recessive parkinsonism in comparison with Parkinson's disease and control.
Neurology 1997;49(5):1257-62.
1997: I Koshimura; H Imai; T Hidano; K Endo; Hideki Mochizuki; T Kondo; Yoshikuni Mizuno
Dimethoxyphenylethylamine and tetrahydropapaverine are toxic to the nigrostriatal system.
Brain research 1997;773(1-2):108-16.
1997: Yumiko Motoi; Y Hattori; Hideto Miwa; K Shina; Yoshikuni Mizuno
[A case of post-hemiplegic painful dystonia following thalamic infarction with good response to botulinus toxin].
Rinshō shinkeigaku = Clinical neurology 1997;37(10):881-6.
1997: Tomonori Kobayashi; Masashi Takanashi; Hideo Mori; M Suzuki; Koichi Suda; Hideki Takubo; Yoshikuni Mizuno
[A 85-year-old woman with one year history of convulsion, dementia, and consciousness disturbance].
Nō to shinkei = Brain and nerve 1997;49(10):953-61.
1997: Yoshikuni Mizuno; H Mochizuki; Y Sugita; K Goto
[Nervous system diseases and apoptosis].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 1997;86(9):1606-10.
1997: Hideto Miwa; Hideo Mori; S Sumino; Shuji Matsuoka; T Shirai; H Imai; Yoshikuni Mizuno
[Neurological CPC.57. An 80-year-old woman with four years history of muscle atrophy involving lower extremities predominantly on the right side].
Nō to shinkei = Brain and nerve 1997;49(9):857-65.
1997: H Yoshino; Nobutaka Hattori; T Urabe; K Uchida; M Tanaka; Yoshikuni Mizuno
Postischemic accumulation of lipid peroxidation products in the rat brain: immunohistochemical detection of 4-hydroxy-2-nonenal modified proteins.
Brain research 1997;767(1):81-6.
1997: N Miyashita; H Imai; Hideo Mori; M Kodera; T Shirai; Yoshikuni Mizuno
[A 76-year-old man with loss of vision and dementia].
Nō to shinkei = Brain and nerve 1997;49(8):773-82.
1997: N Morikawa; Hideo Mori; S Sumino; M Kodera; T Shirai; Tomoyoshi Kondo; Yoshikuni Mizuno
[(Neurological CPC.55). A 60-year-old woman with progressive cerebellar ataxia, myoclonus, and dementia].
Nō to shinkei = Brain and nerve 1997;49(7):663-71.
1997: S Satoh; Hideto Miwa; M Nakano; Y Kazumi; Yoshikuni Mizuno
[Progressive loss of speech output with festinating speech--a case report].
Nō to shinkei = Brain and nerve 1997;49(7):646-9.
1997: T Ozawa; M Hayakawa; K Katsumata; Makoto Yoneda; S Ikebe; Yoshikuni Mizuno
Fragile mitochondrial DNA: the missing link in the apoptotic neuronal cell death in Parkinson's disease.
Biochemical and biophysical research communications 1997;235(1):158-61.
1997: M Yamamoto; I Kondo; N Ogawa; M Asanuma; Y Yamashita; Yoshikuni Mizuno
Genetic association between susceptibility to Parkinson's disease and alpha1-antichymotrypsin polymorphism.
Brain research 1997;759(1):153-5.
1997: A Yoritaka; Nobutaka Hattori; Hideo Mori; K Kato; Yoshikuni Mizuno
An immunohistochemical study on manganese superoxide dismutase in Parkinson's disease.
Journal of the neurological sciences 1997;148(2):181-6.
1997: Yoshikuni Mizuno; Tomoyoshi Kondo
Mortality associated with selegiline in Parkinson's disease. What do the available data mean?
Drug safety : an international journal of medical toxicology and drug experience 1997;16(5):289-94.
1997: Y Ohkuma; Kiyoshi Sato; T Ohtomo; H Ohishi; Hideyuki Mitsuoka; Hideo Mori; S Hirai; Hideki Takubo; N Takeda; K Sato; Yoshikuni Mizuno
[A 29-year-old man with diabetes insipidus and cerebellar ataxia and development of spinal cord swelling 15 years after the onset].
Nō to shinkei = Brain and nerve 1997;49(5):473-81.
1997: K Goto; Hideki Mochizuki; T Hattori; N Nakamura; Yoshikuni Mizuno
Neurotoxic effects of papaverine, tetrahydropapaverine and dimethoxyphenylethylamine on dopaminergic neurons in ventral mesencephalic-striatal co-culture.
Brain research 1997;754(1-2):260-8.
1997: Y Okuma; Y Shimo; K Hatori; T Hattori; S Tanaka; Yoshikuni Mizuno
Familial cortical tremor with epilepsy.
Parkinsonism & related disorders 1997;3(2):83-7.
1997: A Yoritaka; T Hattori; Y Hattori; Hideo Mori; Shuji Matsuoka; T Shirai; Tomoyoshi Kondo; Yoshikuni Mizuno
[A 85-year-old woman with the onset of progressive gait disturbance at 80 years of the age].
Nō to shinkei = Brain and nerve 1997;49(4):379-89.
1997: Keigo Goto; Kiyoshi Sato; H Ienaga; Hideo Mori; Y Hirose; T Shirai; Hideki Takubo; Takashi Danbara; Yoshikuni Mizuno
[A 36-year-old woman with acute onset left hemiplegia and anosognosia].
Nō to shinkei = Brain and nerve 1997;49(3):291-300.
1997: Hiroto Matsumine; M Saito; S Shimoda-Matsubayashi; Hajime Tanaka; A Ishikawa; Y Nakagawa-Hattori; Masayuki Yokochi; Tomonori Kobayashi; S Igarashi; H Takano; K Sanpei; R Koike; Hideo Mori; Tomoyoshi Kondo; Y Mizutani; A A Schäffer; Yasuhiro Yamamura; S Nakamura; S Kuzuhara; Shoji Tsuji; Yoshikuni Mizuno
Localization of a gene for an autosomal recessive form of juvenile Parkinsonism to chromosome 6q25.2-27.
American journal of human genetics 1997;60(3):588-96.
1997: A Yoritaka; Nobutaka Hattori; Hiroyo Yoshino; Yoshikuni Mizuno
Catechol-O-methyltransferase genotype and susceptibility to Parkinson's disease in Japan. Short communication.
Journal of neural transmission (Vienna, Austria : 1996) 1997;104(11-12):1313-7.
1997: Norio Ogawa; I Kanazawa; H Kowa; S Kuno; Yoshikuni Mizuno; K Tashiro; N Yanagisawa
Nationwide multicenter prospective study on the long-term effects of bromocriptine for Parkinson's disease. Final report of a ten-year follow-up.
European neurology 1997;38 Suppl 2():37-49.
1997: Yoshikuni Mizuno; Nobuo Yanagisawa
Analyzer workshop on the treatment of Parkinson's disease.
European neurology 1997;38 Suppl 1():44-57.
1997: Hisanori Kowa; Ichiro Kanazawa; I Goto; S Kuno; Yoshikuni Mizuno; N Ogawa; K Tashiro; N Yanagisawa
Nine-year follow-up study of bromocriptine monotherapy for Parkinson's disease.
European neurology 1997;38 Suppl 1():23-8.
1997: M Yamamoto; M Yokochi; S Kuno; Y Hattori; Y Tsukamoto; H Narabayashi; H Tohgi; Yoshikuni Mizuno; H Kowa; N Yanagisawa; I Kanazawa
Effects of tolcapone, a catechol-O-methyltransferase inhibitor, on motor symptoms and pharmacokinetics of levodopa in patients with Parkinson's disease.
Journal of neural transmission (Vienna, Austria : 1996) 1997;104(2-3):229-36.
1997: Hideki Mochizuki; H Mori; Yoshikuni Mizuno
Apoptosis in neurodegenerative disorders.
Journal of neural transmission. Supplementum 1997;50():125-40.
1997: T Nakamura; A Yoritaka; S Sumino; H Suzuki; Hideo Mori; Koichi Suda; Hideki Takubo; Yoshikuni Mizuno
[A 70-year-old man with a progressive gait disturbance and gaze palsy].
Nō to shinkei = Brain and nerve 1997;49(1):93-100.
1997: M Kudo; Yoshikuni Mizuno; H Morita; M Miyazaki
[31P magnetic resonance spectroscopy(MRS) study in basal ganglia of patients with Parkinson's disease].
Nihon rinsho. Japanese journal of clinical medicine 1997;55(1):255-61.
1997: Kozo Hatori; Tomoyoshi Kondo; Yoshikuni Mizuno
[Levodopa loading test as an early marker of Parkinson's disease].
Nihon rinsho. Japanese journal of clinical medicine 1997;55(1):207-12.
1997: M Saito; H Matsumine; H Tanaka; A Ishikawa; S Matsubayashi; Y Hattori; Yoshikuni Mizuno; S Tsuji
[Clinical characteristics and linkage analysis of autosomal recessive form of juvenile parkinsonism(AR-JP)].
Nihon rinsho. Japanese journal of clinical medicine 1997;55(1):83-8.
1997: Yoshikuni Mizuno
[Concept and diagnostic criteria of Parkinson's disease and parkinsonism].
Nihon rinsho. Japanese journal of clinical medicine 1997;55(1):16-20.
1996: M Mogi; M Harada; T Kondo; Yoshikuni Mizuno; H Narabayashi; Peter Riederer; Toshiharu Nagatsu
The soluble form of Fas molecule is elevated in parkinsonian brain tissues.
Neuroscience letters 1996;220(3):195-8.
1996: Y Hattori; Y Motoi; Hideo Mori; S Takase; Koichi Suda; H Imai; Yoshikuni Mizuno
[A 91-year-old man with a stroke, hypertension, and renal failure].
Nō to shinkei = Brain and nerve 1996;48(12):1155-64.
1996: T Kondo; Yoshikuni Mizuno
[Free radical scavengers].
Nō to shinkei = Brain and nerve 1996;48(12):1099-113.
1996: Nobutaka Hattori; K Goto; Hideo Mori; I Tominaga; T Kondo; Yoshikuni Mizuno
[A 46-year-old man with right-side dominant parkinsonism, who suffered a sudden death].
Nō to shinkei = Brain and nerve 1996;48(11):1059-67.
1996: Y Nakajima; K Matsuda; Yoshikuni Mizuno
Akinesia and axial rigidity without limb rigidity: an intermediate form between progressive supranuclear palsy and pure akinesia of Imai and Narabayashi.
Parkinsonism & related disorders 1996;2(4):209-14.
1996: Y Sugita; Masayuki Yokochi; Akinori Ida; Hideo Mori; T Shirai; H Imai; Yoshikuni Mizuno
[A 43-year-old woman with 18 years history of parkinsonism].
Nō to shinkei = Brain and nerve 1996;48(10):963-71.
1996: S Shimoda-Matsubayashi; Hiroto Matsumine; Tomonori Kobayashi; Y Nakagawa-Hattori; Y Shimizu; Yoshikuni Mizuno
Structural dimorphism in the mitochondrial targeting sequence in the human manganese superoxide dismutase gene. A predictive evidence for conformational change to influence mitochondrial transport and a study of allelic association in Parkinson's disease.
Biochemical and biophysical research communications 1996;226(2):561-5.
1996: N Nakamura; Nobutaka Hattori; M Tanaka; Yoshikuni Mizuno
Specific detection of deleted mitochondrial DNA by in situ hybridization using a chimera probe.
Biochimica et biophysica acta 1996;1308(3):215-21.
1996: M Mogi; M Harada; T Kondo; Yoshikuni Mizuno; H Narabayashi; Peter Riederer; Toshiharu Nagatsu
bcl-2 protein is increased in the brain from parkinsonian patients.
Neuroscience letters 1996;215(2):137-9.
1996: N Nakamura; Satoshi Ohta; M Matsumoto; Hideo Mori; Hideki Takubo; Yoshikuni Mizuno
[A 63 year-old man with progressive gait disturbance and dysarthria].
Nō to shinkei = Brain and nerve 1996;48(9):865-75.
1996: Hideo Mori; K Sato; E Hirasawa; T Kondo; Yoshikuni Mizuno
[A 22-year-old man with long-standing weakness and atrophy predominantly in the lower extremities].
Nō to shinkei = Brain and nerve 1996;48(8):763-71.
1996: Kozo Hatori; Tomoyoshi Kondo; Yoshikuni Mizuno
Levodopa absorption profile in Parkinson's disease: Evidence to indicate qualitative difference from the control.
Parkinsonism & related disorders 1996;2(3):137-44.
1996: T Yamamoto; Tohru Kitada; E Hirasawa; Hideo Mori; Yoshikuni Mizuno
[A 34-year-old woman with delayed motor milestones, high arched palate, and proximal muscle weakness].
Nō to shinkei = Brain and nerve 1996;48(7):677-84.
1996: T Urabe; Nobutaka Hattori; S Nagamatsu; H Sawa; Yoshikuni Mizuno
Expression of glucose transporters in rat brain following transient focal ischemic injury.
Journal of neurochemistry 1996;67(1):265-71.
1996: K Goto; Hideki Mochizuki; H Imai; Haruhiko Akiyama; Yoshikuni Mizuno
An immuno-histochemical study of ferritin in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced hemiparkinsonian monkeys.
Brain research 1996;724(1):125-8.
1996: Hideki Takubo; T Kondo; Hideo Mori; T Miyake; Koichi Suda; Masayuki Yokochi; H Imai; Yoshikuni Mizuno
[A 62-year-old man with familial parkinsonism with the onset at 24 years of the age].
Nō to shinkei = Brain and nerve 1996;48(6):587-97.
1996: Hideo Mori; M Oda; Yoshikuni Mizuno
Cortical ballooned neurons in progressive supranuclear palsy.
Neuroscience letters 1996;209(2):109-12.
1996: H Mochizuki; K Goto; Hideo Mori; Yoshikuni Mizuno
Histochemical detection of apoptosis in Parkinson's disease.
Journal of the neurological sciences 1996;137(2):120-3.
1996: Hideto Miwa; Y Yamaji; H Abe; Yoshikuni Mizuno
Evaluation of the somatosensory evoked blink response in patients with neurological disorders.
Journal of neurology, neurosurgery, and psychiatry 1996;60(5):539-43.
1996: H Miyasaka; H Mori; T Saikawa; T Shirai; T Kondo; H Imai; Yoshikuni Mizuno
[A 78-year-old man with young onset parkinsonism and sudden death].
Nō to shinkei = Brain and nerve 1996;48(5):487-95.
1996: Yoshikuni Mizuno; T Kondo; Hideki Takubo; F Yokochi
[A long-term clinical effect of selegiline hydrochloride on Parkinson's disease].
Nō to shinkei = Brain and nerve 1996;48(5):467-72.
1996: Yoshiaki Furukawa; M Shimadzu; Ali H Rajput; Y Shimizu; T Tagawa; Hideo Mori; Masayuki Yokochi; H Narabayashi; Oleh Hornykiewicz; Yoshikuni Mizuno; Stephen J Kish
GTP-cyclohydrolase I gene mutations in hereditary progressive amd dopa-responsive dystonia.
Annals of neurology 1996;39(5):609-17.
1996: A Yoritaka; Nobutaka Hattori; K Uchida; M Tanaka; E R Stadtman; Yoshikuni Mizuno
Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):2696-701.
1996: Yoshikuni Mizuno; F Yokochi; Satoshi Ohta; Hideo Mori; Hideki Takubo
[A 65-year-old man with Parkinsonism, gaze palsy, and dementia].
Nō to shinkei = Brain and nerve 1996;48(4):381-93.
1996: Y Okuma; Shigeki Tanaka; Y Nomura; Hideo Mori; H Yan; T Shirai; T Kondo; M Segawa; Yoshikuni Mizuno
[A 63-year-old woman with muscle weakness, myotonia, and parkinsonism].
Nō to shinkei = Brain and nerve 1996;48(3):287-97.
1996: Hideto Miwa; Hideo Mori; K Abe; I Hoshino; Yoshikuni Mizuno
[Corticobasal degeneration and progressive supranuclear palsy--differentiation by somatosensory-evoked potentials].
Nō to shinkei = Brain and nerve 1996;48(3):253-7.
1996: N Morikawa; Y Nakagawa-Hattori; Yoshikuni Mizuno
Effect of dopamine, dimethoxyphenylethylamine, papaverine, and related compounds on mitochondrial respiration and complex I activity.
Journal of neurochemistry 1996;66(3):1174-81.
1996: S Matsubayashi; K Sato; M Takase; Hideo Mori; Koichi Suda; T Kondo; Yoshikuni Mizuno
[A 83 year-old woman with dementia, gait disturbance, and convulsion].
Nō to shinkei = Brain and nerve 1996;49(2):185-93.
1996: T Hattori; Tohru Kitada; H Suzuki; H Imai; Yoshikuni Mizuno
[A 56-year-old man with fever, backache and tetraparesis].
Nō to shinkei = Brain and nerve 1996;48(2):183-93.
1996: Hideto Miwa; Yoshikuni Mizuno
[Dystonia preceding dopa-responsive parkinsonism--heterogeneous clinical features].
Nō to shinkei = Brain and nerve 1996;48(2):149-54.
1996: F Takakubo; M Yamamoto; N Ogawa; Y Yamashita; Yoshikuni Mizuno; Ikuko Kondo
Genetic association between cytochrome P450IA1 gene and susceptibility to Parkinson's disease.
Journal of neural transmission (Vienna, Austria : 1996) 1996;103(7):843-9.
1996: K Tashiro; I Goto; I Kanazawa; H Kowa; S Kuno; Yoshikuni Mizuno; N Ogawa; N Yanagisawa
Eight-year follow-up study of bromocriptine monotherapy for Parkinson's disease.
European neurology 1996;36 Suppl 1():32-7.
1996: I Koshimura; N Takeda; T Ohtomo; J Shimada; K Sugano; Hideo Mori; Yoshikuni Mizuno; K Sato
[A 32-year-old man who developed a posterior fossa mass 12 years after the radiation therapy for cerebellar arteriovenous malformation].
Nō to shinkei = Brain and nerve 1996;48(1):81-9.
1996: Yoshikuni Mizuno; S Ikebe; Hideki Mochizuki; H Matumine; T Kondo
[Etiology and pathogenesis of parkinson's disease].
Nō to shinkei = Brain and nerve 1996;48(1):5-17.
1996: J Kojima; A Yoritaka; S Ikebe; Y Nakajima; Yoshikuni Mizuno
[The relationship between visual agnosia and visual pathway for perception].
Nō to shinkei = Brain and nerve 1996;48(1):31-7.
1996: Yoshiaki Furukawa; Yoshikuni Mizuno; H Narabayashi
Early-onset parkinsonism with dystonia. Clinical and biochemical differences from hereditary progressive dystonia or DOPA-responsive dystonia.
Advances in neurology 1996;69():327-37.
1996: Hideto Miwa; Kozo Hatori; T Kondo; H Imai; Yoshikuni Mizuno
Thalamic tremor: case reports and implications of the tremor-generating mechanism.
Neurology 1996;46(1):75-9.
1995: Y Morimoto; N Murayama; A Kuwano; Ikuko Kondo; Y Yamashita; Yoshikuni Mizuno
Association analysis of a polymorphism of the monoamine oxidase B gene with Parkinson's disease in a Japanese population.
American journal of medical genetics 1995;60(6):570-2.
1995: Y Nakagawa-Hattori; T Hattori; T Kondo; Yoshikuni Mizuno
S-methylation in Parkinson's disease.
Neurology 1995;45(12):2279-81.
1995: M Nagaoka; N Nakamura; A Yamamura; Hideo Mori; T Shirai; Yoshikuni Mizuno
[A 75-year-old man with parkinsonism and sudden death].
Nō to shinkei = Brain and nerve 1995;47(12):1199-208.
1995: Hiroto Matsumine; T Shimizu; K Sato; Yoshikuni Mizuno
[Anosognosia, 2)anosodiaphoria].
Nō to shinkei = Brain and nerve 1995;47(12):1196-7.
1995: Nobutaka Hattori; H Suzuki; Y Wang; Shinsei Minoshima; Nobuyoshi Shimizu; Hiroyo Yoshino; R Kurashima; M Tanaka; T Ozawa; Yoshikuni Mizuno
Structural organization and chromosomal localization of the human nuclear gene (NDUFV2) for the 24-kDa iron-sulfur subunit of complex I in mitochondrial respiratory chain.
Biochemical and biophysical research communications 1995;216(3):771-7.
1995: Yoshikuni Mizuno; H Mori; T Kondo
Parkinson's disease: from etiology to treatment.
Internal medicine (Tokyo, Japan) 1995;34(11):1045-54.
1995: Nobutaka Hattori; K Sugano; M Wakiya; Hideo Mori; T Shirai; Yoshikuni Mizuno
[A 56-year-old woman with parkinsonism and dementia with the age of onset at 41 years].
Nō to shinkei = Brain and nerve 1995;47(9):911-9.
1995: K Hirabayashi; N Morikawa; Hideo Mori; T Miyake; Koichi Suda; T Kondo; Yoshikuni Mizuno
[A 86-year-old woman with dementia, gait and speech disturbance, and right hemiparesis].
Nō to shinkei = Brain and nerve 1995;47(8):803-12.
1995: Hideki Takubo; S Satoh; Hideo Mori; M Tsukahara; Koichi Suda; H Imai; Yoshikuni Mizuno
[A 57-year-old woman with gait disturbance, headache, character change, convulsion, and coma].
Nō to shinkei = Brain and nerve 1995;47(7):699-708.
1995: T Kondo; H Mochizuki; G Ueda; Hiroshi Mori; T Shirai; H Imai; Yoshikuni Mizuno
[A 51-year-old man with early onset parkinsonism].
Nō to shinkei = Brain and nerve 1995;47(6):603-12.
1995: N Imamura; Hideto Miwa; M Hironishi; K Goto; Yoshikuni Mizuno
[A characteristic blink response observed in a patient with Lance-Adams syndrome--somatosensory-evoked blink response].
Nō to shinkei = Brain and nerve 1995;47(6):581-4.
1995: Yoshikuni Mizuno; S Ikebe; Nobutaka Hattori; Y Nakagawa-Hattori; Hideki Mochizuki; M Tanaka; T Ozawa
Role of mitochondria in the etiology and pathogenesis of Parkinson's disease.
Biochimica et biophysica acta 1995;1271(1):265-74.
1995: Y Hattori; C Nohara; E Hirasawa; Hideo Mori; H Imai; Yoshikuni Mizuno
[A 21-year-old man with distal dominant progressive muscle atrophy].
Nō to shinkei = Brain and nerve 1995;47(5):509-18.
1995: H Imai; Yoshiaki Furukawa; S Sumino; Hideo Mori; G Ueda; T Shirai; T Kondo; Yoshikuni Mizuno
[A 65-year-old woman with dysarthria, dysphagia, weakness, and gait disturbance].
Nō to shinkei = Brain and nerve 1995;47(4):399-410.
1995: Yoshikuni Mizuno; T Kondo; H Narabayashi
Pergolide in the treatment of Parkinson's disease.
Neurology 1995;45(3 Suppl 3):S13-21.
1995: Y Nakajima; T Hattori; Yoshikuni Mizuno
[Absence of P300 in patients with bilateral hippocampal lesions caused by herpes simplex encephalitis].
Nō to shinkei = Brain and nerve 1995;47(3):270-5.
1995: Yoshiaki Furukawa; K Nishi; Yoshikuni Mizuno; H Narabayashi
[Significance of CSF biopterin and neopterin in hereditary progressive dystonia with marked diurnal fluctuation (HPD)--a clue to pathogenesis].
Nō to shinkei = Brain and nerve 1995;47(3):261-8.
1995: Hideki Mochizuki; S Satoh; M Saikawa; Hideo Mori; T Shirai; T Kondo; Yoshikuni Mizuno
[A 74-year-old man with urinary incontinence, right leg weakness and multiple cranial nerve palsies].
Nō to shinkei = Brain and nerve 1995;47(2):199-209.
1995: Hideto Miwa; N Imamura; K Kogahara; T Ohori; Yoshikuni Mizuno
Somatosensory evoked blink response: findings in patients with Miller Fisher syndrome and in normal subjects.
Journal of neurology, neurosurgery, and psychiatry 1995;58(1):95-9.
1995: Y Furukawa; Yoshikuni Mizuno; K Nishi; H Narabayashi
A clue to the pathogenesis of dopa-responsive dystonia.
Annals of neurology 1995;37(1):139-40.
1995: Midori Anno; K Gotoh; E Hirasawa; Hideo Mori; Y Nakajima; Yoshikuni Mizuno
[A 54-year-old man with progressive proximal muscle atrophy and gynecomastia].
Nō to shinkei = Brain and nerve 1995;47(1):87-96.
1994: T Komiya; M Kudo; T Urabe; Yoshikuni Mizuno
Compliance with antiplatelet therapy in patients with ischemic cerebrovascular disease. Assessment by platelet aggregation testing.
Stroke; a journal of cerebral circulation 1994;25(12):2337-42.
1994: H Miyasaka; C Nohara; H Ohtani; Koichi Suda; Hideo Mori; Y Nakajima; Yoshikuni Mizuno
[A 65-year-old woman with headache, facial pain, and progressive multiple cranial neuropathy].
Nō to shinkei = Brain and nerve 1994;46(11):1101-11.
1994: Kozo Hatori; N Morikawa; T Nitta; Hideo Mori; K Satoh; Yoshikuni Mizuno
[A 37-year-old man with memory loss, homonymous hemianopsia, and elevation of anti-herpes simplex virus antibody titer].
Nō to shinkei = Brain and nerve 1994;46(10):1001-9.
1994: Yoshikuni Mizuno; S Ikebe; Nobutaka Hattori; Hideki Mochizuki; Y Nakagawa-Hattori; T Kondo
Studies on the pathogenesis of Parkinson's disease in Japan.
Archives of gerontology and geriatrics 1994;19(2):105-21.
1994: T Komiya; Toshihide Shike; Hideo Mori; M L Santo; Koichi Suda; T Kondo; Yoshikuni Mizuno
[A 54-year-old man with generalized muscle atrophy and oculomotor paresis].
Nō to shinkei = Brain and nerve 1994;46(9):895-904.
1994: Y Nakajima; M Sekiya; K Goto; H Miyasaka; Yoshikuni Mizuno
[Characteristic event-related potentials evoked by somatosensory tasks in a patient with right-left disorientation and finger agnosia].
Nō to shinkei = Brain and nerve 1994;46(9):873-8.
1994: Y Hattori; Y Goto; R Sakuta; I Nonaka; Yoshikuni Mizuno; S Horai
Point mutations in mitochondrial tRNA genes: sequence analysis of chronic progressive external ophthalmoplegia (CPEO)
Journal of the neurological sciences 1994;125(1):50-5.
1994: Yoshikuni Mizuno; T Kondo; Hideo Mori
Various aspects of motor fluctuations and their management in Parkinson's disease.
Neurology 1994;44(7 Suppl 6):S29-34.
1994: T Kondo; N Nakamura; T Iesaki; A Kono; H Oomuro; Hideo Mori; T Shirai; H Yamaguchi; Yoshikuni Mizuno
[A 46-year-old man with cardiac failure and statues epileptics].
Nō to shinkei = Brain and nerve 1994;46(7):691-701.
1994: Yoshiaki Furukawa; Y Nakajima; M Nakagawa; M Matsumoto; Hideo Mori; Yoshikuni Mizuno
[A 75-year-old woman with multiple cranial nerve palsies and a paranasal mass].
Nō to shinkei = Brain and nerve 1994;46(6):593-600.
1994: S Hatta; Hideki Mochizuki; Y Kuru; H Miwa; T Kondo; H Mori; Yoshikuni Mizuno
Serial neuroradiological studies in focal cerebritis.
Neuroradiology 1994;36(4):285-8.
1994: Hiroto Matsumine; S Matsubayashi; T Nitta; T Matsumoto; Hideo Mori; T Yamamoto; K Sato; Yoshikuni Mizuno
[A 52-year-old man with sensory aphasia and multiple intracranial masses].
Nō to shinkei = Brain and nerve 1994;46(5):499-506.
1994: Yoshikuni Mizuno; T Kondo; Hideki Takubo; F Yokochi
[A long-term clinical effect of selegiline hydrochloride on Parkinson's disease].
Nō to shinkei = Brain and nerve 1994;46(5):465-71.
1994: Yoshikuni Mizuno; Y Nakajima
[The 3 major symptoms and their physiopathology in Parkinson disease].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 1994;83(4):544-8.
1994: H Imai; S Matsubayashi; M L Santo; Hideo Mori; Koichi Suda; T Kondo; Yoshikuni Mizuno
[A 85-year-old right-handed woman with aphasia and left hemiparesis].
Nō to shinkei = Brain and nerve 1994;46(4):397-405.
1994: Hideki Mochizuki; N Nakamura; K Nishi; Yoshikuni Mizuno
Apoptosis is induced by 1-methyl-4-phenylpyridinium ion (MPP+) in ventral mesencephalic-striatal co-culture in rat.
Neuroscience letters 1994;170(1):191-4.
1994: N Nakamura; Y Furukawa; Keiko Fujiki; M Hayakawa; Yoshikuni Mizuno
[Leber's hereditary optic neuropathy with onset at the age of 54 years].
Rinshō shinkeigaku = Clinical neurology 1994;34(3):258-60.
1994: M Hironishi; I Koshimura; K Nishi; T Komiya; Yoshikuni Mizuno
[Pretectal syndrome caused by a plaque of multiple sclerosis].
Rinshō shinkeigaku = Clinical neurology 1994;34(3):236-40.
1994: K Matsuda; Kozo Hatori; H Ohtani; Hideo Mori; Koichi Suda; H Imai; Yoshikuni Mizuno
[A 78-year-old man with progressive gait disturbance, dysphagia, and dementia].
Nō to shinkei = Brain and nerve 1994;46(3):297-305.
1994: J Yokota; H Imai; Yoshikuni Mizuno; M Hishii; M Ito
[Unilateral supranuclear abducens palsy in a pineal tumor].
Nō to shinkei = Brain and nerve 1994;46(3):291-5.
1994: Yoshikuni Mizuno
[Parkinson's disease].
Nō to shinkei = Brain and nerve 1994;46(3):217-27.
1994: Hideki Mochizuki; H Imai; K Endo; K Yokomizo; Y Murata; Nobutaka Hattori; Yoshikuni Mizuno
Iron accumulation in the substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced hemiparkinsonian monkeys.
Neuroscience letters 1994;168(1-2):251-3.
1994: Yoshikuni Mizuno; S Matuda; Hiroyo Yoshino; Hideo Mori; Nobutaka Hattori; S Ikebe
An immunohistochemical study on alpha-ketoglutarate dehydrogenase complex in Parkinson's disease.
Annals of neurology 1994;35(2):204-10.
1994: K Tanabe; F Yokochi; S Hirai; Hideo Mori; Koichi Suda; T Kondo; Yoshikuni Mizuno
[A 75-year-old man with parkinsonism and delirium].
Nō to shinkei = Brain and nerve 1994;46(1):85-92.
1994: Nobuo Yanagisawa; I Kanazawa; I Goto; H Kowa; S Kuno; Yoshikuni Mizuno; K Tashiro; N Ogawa
Seven-year follow-up study of bromocriptine therapy for Parkinson's disease.
European neurology 1994;34 Suppl 3():29-35.
1993: Yoshikuni Mizuno
[Diagnostic criteria for brain death].
Rinshō shinkeigaku = Clinical neurology 1993;33(12):1318-20.
1993: Masayuki Yokochi; S Takaoka; H Kawano; Hideo Mori; T Shirai; H Imai; Yoshikuni Mizuno
[A 77-year-old woman with myoclonus and epilepsy].
Nō to shinkei = Brain and nerve 1993;45(12):1173-85.
1993: Y Ishigaki; M Hironishi; T Toganou; T Matsumoto; Satoshi Ohta; Koichi Suda; K Nishi; H Yamaguchi; Yoshikuni Mizuno
[A 79-year-old man with rapidly progressive tetraparesis].
Nō to shinkei = Brain and nerve 1993;45(11):1081-9.
1993: S Ikebe; F Yokochi; T Wada; A Arakawa; Hideo Mori; Koichi Suda; T Kondo; Yoshikuni Mizuno
[A 66-year-old man with backache and progressive difficulty of gait].
Nō to shinkei = Brain and nerve 1993;45(10):981-90.
1993: Shigeki Tanaka; Tohru Kitada; A Kanazawa; G Ueda; K Noguchi; Hideo Mori; T Kondo; T Shirai; Yoshikuni Mizuno
[A 62-year-old man with multiple cranial nerve palsies on the right side and a pelvic mass].
Nō to shinkei = Brain and nerve 1993;45(8):777-87.
1993: Yoshikuni Mizuno; Shigeki Tanaka; Hideo Mori; T Kondo
[A 61-year-old man with rapidly progressing dementia and gait disturbance].
Nō to shinkei = Brain and nerve 1993;45(7):679-85.
1993: Y Ohkuma; S Hatta; M Kubota; H Kohno; Y Mizutani; T Shirai; T Sato; H Imai; H Koide; Yoshikuni Mizuno
[A 70-year-old man with right hemiparesis and mutism].
Nō to shinkei = Brain and nerve 1993;45(6):579-84.
1993: H Suzuki; S Kawai; R Okada; Y Hayashi; A Kanazawa; Yoshikuni Mizuno; K Obata; H Shiotsu; N Kuwabara
[Autopsy results of an elderly case of Parkinson's disease and aorto-esophageal fistula who died of a massive hematemesis during prolonged bed rest].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 1993;30(5):387-92.
1993: Y Nakajima; Tohru Kitada; Y Mizutani; Y Yamamoto; N Kuwabara; T Sato; T Kondo; Yoshikuni Mizuno
[A 50-year-old man with metamorphopsia and optic nerve swelling].
Nō to shinkei = Brain and nerve 1993;45(5):485-92.
1993: K Nishi; Tohru Kitada; Hideo Mori; T Wada; N Kuwabara; H Imai; T Sato; Yoshikuni Mizuno
[A 81-year-old man with dementia, gait disturbance, hemiparesis, and sympathetic apraxia].
Nō to shinkei = Brain and nerve 1993;45(4):389-95.
1993: Hideto Miwa; N Imamura; Y Mizutani; H Shiotsu; N Kuwabara; M Nagaoka; T Sato; Yoshikuni Mizuno
[A 93-year-old woman presenting consciousness disturbance, left hemiplegia, and respiratory distress].
Nō to shinkei = Brain and nerve 1993;45(3):281-7.
1993: Yoshikuni Mizuno
[Clinical subtypes of Parkinson's disease].
Nō to shinkei = Brain and nerve 1993;45(2):105-12.
1993: T Yamamoto; K Gotoh; T Sato; H Shiotsu; N Kuwabara; M Nagaoka; Yoshikuni Mizuno
[Forty-six-year-old woman with progressive external ophthalmoplegia and limb weakness].
Nō to shinkei = Brain and nerve 1993;45(1):85-92.
1993: Yoshiaki Furukawa; K Nishi; T Kondo; Yoshikuni Mizuno; H Narabayashi
CSF biopterin levels and clinical features of patients with juvenile parkinsonism.
Advances in neurology 1993;60():562-7.
1993: Yoshikuni Mizuno; S Ikebe; Nobutaka Hattori; T Kondo; M Tanaka; T Ozawa
Mitochondrial energy crisis in Parkinson's disease.
Advances in neurology 1993;60():282-7.
1993: Nobutaka Hattori; S Ikebe; M Tanaka; T Ozawa; Yoshikuni Mizuno
Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in Parkinson's disease.
Advances in neurology 1993;60():292-6.
1992: Yoshikuni Mizuno
[Japanese clinical statistical data of patients with parkinson's disease].
Nihon rinsho. Japanese journal of clinical medicine 1992;50 Suppl():109-17.
1992: Yoshiaki Furukawa; K Nishi; T Kondo; K Tanabe; Yoshikuni Mizuno
Significance of CSF total neopterin and biopterin in inflammatory neurological diseases.
Journal of the neurological sciences 1992;111(1):65-72.
1992: A Yoritaka; K Kogahara; Hiroyo Yoshino; H Imai; Yoshikuni Mizuno
[Clinical and neuroradiological studies on orbital myositis and Tolosa-Hunt syndrome].
Rinshō shinkeigaku = Clinical neurology 1992;32(6):593-9.
1992: Yoshiaki Furukawa; K Nishi; T Kondo; Yoshikuni Mizuno; H Narabayashi
Juvenile parkinsonism: ventricular CSF biopterin levels and clinical features.
Journal of the neurological sciences 1992;108(2):207-13.
1992: Y Nakagawa-Hattori; Hiroyo Yoshino; T Kondo; Yoshikuni Mizuno; S Horai
Is Parkinson's disease a mitochondrial disorder?
Journal of the neurological sciences 1992;107(1):29-33.
1992: Hideto Miwa; M Hirasawa; Hiroyo Yoshino; Y Hayashi; Yoshikuni Mizuno
[The early hemiparesis of stroke in evolution of basilar artery--case report].
Nō to shinkei = Brain and nerve 1992;44(1):49-52.
1992: J Yokota; H Imai; K Seki; C Ninomiya; Yoshikuni Mizuno
Orthostatic tremor associated with voice tremor.
European neurology 1992;32(6):354-8.
1992: T Nakanishi; M Iwata; I Goto; I Kanazawa; H Kowa; T Mannen; Yoshikuni Mizuno; H Nishitani; N Ogawa; A Takahashi
Nation-wide collaborative study on the long-term effects of bromocriptine in the treatment of parkinsonian patients. Final report.
European neurology 1992;32 Suppl 1():9-22.
1992: T Nakanishi; I Kanazawa; M Iwata; I Goto; H Kowa; T Mannen; Yoshikuni Mizuno; H Nishitani; N Ogawa; A Takahashi
Nation-wide collaborative study on the long-term effects of bromocriptine in the treatment of parkinsonian patients: analysis on the maintenance and the change of the original mode of treatment.
European neurology 1992;32 Suppl 1():23-9.
1992: Yoshikuni Mizuno
Drug therapy of Parkinson's disease. An overview.
European neurology 1992;32 Suppl 1():3-8.
1992: Hiroyo Yoshino; Y Nakagawa-Hattori; T Kondo; Yoshikuni Mizuno
Mitochondrial complex I and II activities of lymphocytes and platelets in Parkinson's disease.
Journal of neural transmission. Parkinson's disease and dementia section 1992;4(1):27-34.
1991: T Mannen; Yoshikuni Mizuno; M Iwata; I Goto; Ichiro Kanazawa; H Kowa; H Nishitani; N Ogawa; A Takahashi; K Tashiro
A multi-center, double-blind study on slow-release bromocriptine in the treatment of Parkinson's disease.
Neurology 1991;41(10):1598-602.
1991: M Hirasawa; M Nakano; N Shiohama; T Komiya; Yoshikuni Mizuno
[Amnestic syndrome with bilateral lesions restricted to the field CA-1 of both hippocampi--a case report with CT and MRI findings].
Rinshō shinkeigaku = Clinical neurology 1991;31(10):1147-50.
1991: Kozo Hatori; Takao Urabe; A Kanazawa; Yoshikuni Mizuno
[A case of brainstem vascular malformation with isolated trochlear nerve palsy as the initial symptom].
Nō to shinkei = Brain and nerve 1991;43(10):965-8.
1991: Nobutaka Hattori; M Tanaka; T Ozawa; Yoshikuni Mizuno
Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in Parkinson's disease.
Annals of neurology 1991;30(4):563-71.
1991: Yoshikuni Mizuno
[Parkinson's disease; etiology and animal model].
Nō to shinkei = Brain and nerve 1991;43(8):703-11.
1991: K Takahashi; Hideki Mochizuki; Hiroyo Yoshino; H Imai; Yoshikuni Mizuno
[Post-hemiplegic dystonia with a discrete lesion in the postero-lateral part of the contralateral putamen].
Rinshō shinkeigaku = Clinical neurology 1991;31(6):662-5.
1991: T Nakanishi; Yoshikuni Mizuno; I Goto; M Iwata; I Kanazawa; H Kowa; T Mannen; H Nishitani; N Ogawa; A Takahashi
A nationwide collaborative study on the long-term effects of bromocriptine in patients with Parkinson's disease. The fourth interim report.
European neurology 1991;31 Suppl 1():3-16.
1990: T Ozawa; M Tanaka; S Ikebe; K Ohno; T Kondo; Yoshikuni Mizuno
Quantitative determination of deleted mitochondrial DNA relative to normal DNA in parkinsonian striatum by a kinetic PCR analysis.
Biochemical and biophysical research communications 1990;172(2):483-9.
1990: K Abe; S Ohta; T Komiya; N Sakamoto; Yoshikuni Mizuno
Fibromuscular dysplasia complicated by primary thrombocythemia presenting recurrent ischemic cerebrovascular accidents: a case report.
Japanese journal of medicine 1990;29(5):548-54.
1990: S Ikebe; M Tanaka; K Ohno; W Sato; K Hattori; T Kondo; Yoshikuni Mizuno; T Ozawa
Increase of deleted mitochondrial DNA in the striatum in Parkinson's disease and senescence.
Biochemical and biophysical research communications 1990;170(3):1044-8.
1990: K Suzuki; Yoshikuni Mizuno; M Yoshida
Inhibition of mitochondrial respiration by 1,2,3,4-tetrahydroisoquinoline-like endogenous alkaloids in mouse brain.
Neurochemical research 1990;15(7):705-10.
1990: Yoshikuni Mizuno; K Suzuki; S Ohta
Postmortem changes in mitochondrial respiratory enzymes in brain and a preliminary observation in Parkinson's disease.
Journal of the neurological sciences 1990;96(1):49-57.
1990: N Shioya; J Yokota; Hideto Miwa; T Hattori; Yoshikuni Mizuno
[Vestibular ataxia caused by meningeal carcinomatosis].
Rinshō shinkeigaku = Clinical neurology 1990;30(3):308-13.
1990: Yoshikuni Mizuno
[The role of oxygen free radicals in the aging of the brain].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 1990;27(2):182-7.
1990: T Nakanishi; I Kanazawa; I Goto; M Iwata; H Kowa; T Mannen; Yoshikuni Mizuno; H Nishitani; N Ogawa; A Takahashi
Third interim report of the nationwide collaborative study on the long-term effects of bromocriptine in the treatment of parkinsonian patients.
European neurology 1990;30 Suppl 1():3-8.
1990: S Shimoda-Matsubayashi; Y Kuru; H Sumie; T Ito; Nobutaka Hattori; Y Okuma; Yoshikuni Mizuno
MRI findings in the mild type of mucopolysaccharidosis II (Hunter's syndrome).
Neuroradiology 1990;32(4):328-30.
1989: Yoshikuni Mizuno
[Contribution of MPTP to studies on the pathogenesis of Parkinson's disease].
Rinshō shinkeigaku = Clinical neurology 1989;29(12):1494-6.
1989: Yoshikuni Mizuno; S Ohta; M Tanaka; Shinzaburo Takamiya; K Suzuki; T Sato; H Oya; T Ozawa; Y Kagawa
Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease.
Biochemical and biophysical research communications 1989;163(3):1450-5.
1989: T Nakanishi; M Iwata; I Goto; I Kanazawa; H Kowa; T Mannen; Yoshikuni Mizuno; H Nishitani; N Ogawa; A Takahashi
Second interim report of the nation-wide collaborative study on the long-term effects of bromocriptine in the treatment of parkinsonian patients.
European neurology 1989;29 Suppl 1():3-8.
1988: H Sakuma; Sadao Takase; Yoshikuni Mizuno; K Teramura; K Hanew
Hypothalamo-pituitary dopaminergic system in patients with myotonic dystrophy.
The Tohoku journal of experimental medicine 1988;156(3):291-8.
1988: T Nakanishi; Yoshikuni Mizuno; I Goto; M Iwata; I Kanazawa; H Kowa; T Mannen; H Nishitani; N Ogawa; A Takahashi
A nation-wide collaborative study on the long-term effects of bromocriptine in patients with Parkinson's disease. First interim report in Japan.
European neurology 1988;28 Suppl 1():3-8.
1986: Y Tanaka; K Niijima; Yoshikuni Mizuno; M Yoshida
Changes in gamma-aminobutyrate, glutamate, aspartate, glycine, and taurine contents in the striatum after unilateral nigrostriatal lesions in rats.
Experimental neurology 1986;91(2):259-68.
1985: Y Toyokura; Yoshikuni Mizuno; M Kase; I Sobue; Y Kuroiwa; H Narabayashi; M Uono; T Nakanishi; M Kameyama; H Ito
Effects of bromocriptine on parkinsonism. A nation-wide collaborative double-blind study.
Acta neurologica Scandinavica 1985;72(2):157-70.
1985: T Saito; Yoshikuni Mizuno; M Yoshida
[Differential diagnosis of parkinsonism based on a semiquantitative scoring system--chiefly to discriminate two major causes, paralysis agitans and vascular parkinsonism].
Rinshō shinkeigaku = Clinical neurology 1985;25(5):591-6.
1984: T Katsuki; N Shimizu; Yoshikuni Mizuno
[Onset-and end-of-dose dyskinesias induced by L-dopa treatment in a patient with juvenile parkinsonism].
Nō to shinkei = Brain and nerve 1984;36(12):1201-5.
1984: Yoshikuni Mizuno; Y Joshita; M Yoshida; J Kaneko; Y Tanaka; Y Nagatsuka
[Effects of the "drug holiday" on problems of long-term levodopa therapy against Parkinson's disease].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 1984;73(4):474-80.
1984: Y Tanaka; Yoshikuni Mizuno
[GABA, glutamate, aspartate, glycine, and taurine contents in spinocerebellar degeneration and parkinsonism].
Rinshō shinkeigaku = Clinical neurology 1984;24(3):256-63.
1983: Yoshikuni Mizuno; Y Joshita
[Superoxide dismutase activities in multi-system degeneration and parkinsonism].
Rinshō shinkeigaku = Clinical neurology 1983;23(3):203-11.
1982: Yoshikuni Mizuno
[A study on long-term levodopa therapy in Parkinson's disease].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 1982;71(11):1553-9.
1981: J Seki; Y Arakawa; K Imai; Z Tamura; S Yoshiue; Yoshikuni Mizuno; K Yamada; M Matsue; H Narabayashi
High-performance liquid chromatographic determination of L-3,4-dihydroxy-phenylalanine (L-DOPA) and its metabolites in the urine of patients with Parkinson's disease, control patients and normal subjects after oral administration of L-DOPA.
Chemical & pharmaceutical bulletin 1981;29(3):789-95.
1979: Yoshikuni Mizuno; T Ariga
[Cerebrospinal fluid homovanillic acid in paralysis agitans and spinocerebellar degeneration (author's transl)].
Rinshō shinkeigaku = Clinical neurology 1979;19(6):367-71.
1979: Yoshikuni Mizuno
[Cerebrospinal fluid methoxyhydroxy-phenylene glycol in Parkinson's disease and spinocerebellar degeneration (author's transl)].
Nō to shinkei = Brain and nerve 1979;31(3):309-12.
1978: Yoshikuni Mizuno
[Striano-nigral degeneration].
Nihon rinsho. Japanese journal of clinical medicine 1978;Suppl():1720-1.
1977: Yoshikuni Mizuno
Simple gas chromatographic analysis of plasma dopa and dopamine.
Clinica chimica acta; international journal of clinical chemistry 1977;74(1):11-9.
1976: Yoshikuni Mizuno
[Effects and side effects of levodopa in parkinsonism - results of a collaborative study. (3) Side effects of levodopa].
Rinshō shinkeigaku = Clinical neurology 1976;16(12):874-6.
1976: Yoshikuni Mizuno; M Yoshida; T Obayashi; A Ueki
[Combined treatment of Parkinsonism with L-dopa and peripheral dopa decarboxylase inhibitors--clinical course of 13 cases and levels of serum/dopa and dopamine].
Rinshō shinkeigaku = Clinical neurology 1976;16(7):511-9.
1975: M Yoshida; Yoshikuni Mizuno
[Physiology and pharmacology of extrapyramidal tract].
Nihon rinsho. Japanese journal of clinical medicine 1975;33(10):2964-77.