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Yoshiyuki Mizushina

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Kuramochi Kouji; Fukudome Keishi; Kuriyama Isoko; Takeuchi Toshifumi; Sato Yoshihiro; Kamisuki Shinji; Tsubaki Kazunori; Sugawara Fumio; Yoshida Hiromi; Mizushina Yoshiyuki
Synthesis and structure-activity relationships of dehydroaltenusin derivatives as selective DNA polymerase alpha inhibitors.
Matsui Yuki; Hada Takahiko; Maeda Naoki; Sato Yoshihiro; Yamaguchi Yasuhiro; Takeuchi Toshifumi; Takemura Masaharu; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Mizushina Yoshiyuki
Structure and activity relationship of monogalactosyl diacylglycerols, which selectively inhibited in vitro mammalian replicative DNA polymerase activity and human cancer cell growth.
Mizushina Yoshiyuki
Specific inhibitors of mammalian DNA polymerase species.

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All Publications

2009: Kuramochi Kouji; Fukudome Keishi; Kuriyama Isoko; Takeuchi Toshifumi; Sato Yoshihiro; Kamisuki Shinji; Tsubaki Kazunori; Sugawara Fumio; Yoshida Hiromi; Mizushina Yoshiyuki
Synthesis and structure-activity relationships of dehydroaltenusin derivatives as selective DNA polymerase alpha inhibitors.
Bioorganic & medicinal chemistry 2009;17(20):7227-38.
2009: Matsui Yuki; Hada Takahiko; Maeda Naoki; Sato Yoshihiro; Yamaguchi Yasuhiro; Takeuchi Toshifumi; Takemura Masaharu; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Mizushina Yoshiyuki
Structure and activity relationship of monogalactosyl diacylglycerols, which selectively inhibited in vitro mammalian replicative DNA polymerase activity and human cancer cell growth.
Cancer letters 2009;283(1):101-7.
2009: Mizushina Yoshiyuki
Specific inhibitors of mammalian DNA polymerase species.
Bioscience, biotechnology, and biochemistry 2009;73(6):1239-51.
2009: Kayashima Tomoko; Mori Masaharu; Yoshida Hiromi; Mizushina Yoshiyuki; Matsubara Kiminori
1,4-Naphthoquinone is a potent inhibitor of human cancer cell growth and angiogenesis.
Cancer letters 2009;278(1):34-40.
2009: Nishimura Katsumi; Takenaka Yukiko; Kishi Manami; Tanahashi Takao; Yoshida Hiromi; Okuda Chiaki; Mizushina Yoshiyuki
Synthesis and DNA polymerase alpha and beta inhibitory activity of alkyl p-coumarates and related compounds.
Chemical & pharmaceutical bulletin 2009;57(5):476-80.
2009: Kumamoto-Yonezawa Yuko; Sasaki Ryohei; Ota Yosuke; Suzuki Yoko; Fukushima Shoji; Hada Takahiko; Uryu Keisuke; Sugimura Kazuro; Yoshida Hiromi; Mizushina Yoshiyuki
Cell cycle arrest triggered by conjugated eicosapentaenoic acid occurs through several mechanisms including G1 checkpoint activation by induced RPA and ATR expression.
Biochimica et biophysica acta 2009;1790(5):339-46.
2009: Kimura Takuma; Takeuchi Toshifumi; Kumamoto-Yonezawa Yuko; Ohashi Eiji; Ohmori Haruo; Masutani Chikahide; Hanaoka Fumio; Sugawara Fumio; Yoshida Hiromi; Mizushina Yoshiyuki
Penicilliols A and B, novel inhibitors specific to mammalian Y-family DNA polymerases.
Bioorganic & medicinal chemistry 2009;17(5):1811-6.
2009: Mizushina Yoshiyuki; Manita Daisuke; Takeuchi Toshifumi; Sugawara Fumio; Kumamoto-Yonezawa Yuko; Matsui Yuki; Takemura Masaharu; Sasaki Mitsuru; Yoshida Hiromi; Takikawa Hirosato
The inhibitory action of kohamaic acid A derivatives on mammalian DNA polymerase beta.
Molecules (Basel, Switzerland) 2009;14(1):102-21.
2008: Kuriyama Isoko; Fukudome Keishi; Kamisuki Shinji; Kuramochi Kouji; Tsubaki Kazunori; Sakaguchi Kengo; Sugawara Fumio; Yoshida Hiromi; Mizushina Yoshiyuki
The specific inhibitory effect of demethoxydehydroaltenusin, a derivative of dehydroaltenusin, on mammalian DNA polymerase alpha.
International journal of molecular medicine 2008;22(6):793-9.
2008: Takikawa Hirosato; Kamatani Naoki; Nakanishi Kohei; Tashiro Takuya; Sasaki Mitsuru; Yoshida Hiromi; Mizushina Yoshiyuki
Synthetic studies on kohamaic acids: synthesis of structurally simplified analogs of kohamaic acid A.
Bioscience, biotechnology, and biochemistry 2008;72(11):3071-4.
2008: Matsubara Kiminori; Kayashima Tomoko; Mori Masaharu; Yoshida Hiromi; Mizushina Yoshiyuki
Inhibitory effects of vitamin K3 on DNA polymerase and angiogenesis.
International journal of molecular medicine 2008;22(3):381-7.
2008: Maeda Naoki; Kokai Yasuo; Ohtani Seiji; Sahara Hiroeki; Kumamoto-Yonezawa Yuko; Kuriyama Isoko; Hada Takahiko; Sato Noriyuki; Yoshida Hiromi; Mizushina Yoshiyuki
Anti-tumor effect of orally administered spinach glycolipid fraction on implanted cancer cells, colon-26, in mice.
Lipids 2008;43(8):741-8.
2008: Mizushina Yoshiyuki; Takeuchi Toshifumi; Hada Takahiko; Maeda Naoki; Sugawara Fumio; Yoshida Hiromi; Fujita Masatoshi
The inhibitory action of SQDG (sulfoquinovosyl diacylglycerol) from spinach on Cdt1-geminin interaction.
Biochimie 2008;90(6):947-56.
2008: Kuramochi Kouji; Yukizawa Shunsuke; Ikeda Seiki; Sunoki Takashi; Arai Satoshi; Matsui Rie; Morita Akinori; Mizushina Yoshiyuki; Sakaguchi Kengo; Sugawara Fumio; Ikekita Masahiko; Kobayashi Susumu
Syntheses and applications of fluorescent and biotinylated epolactaene derivatives: Epolactaene and its derivative induce disulfide formation.
Bioorganic & medicinal chemistry 2008;16(9):5039-49.
2008: Nishida Masayuki; Ida Noriko; Horio Mao; Takeuchi Toshifumi; Kamisuki Shinji; Murata Hiroshi; Kuramochi Kouji; Sugawara Fumio; Yoshida Hiromi; Mizushina Yoshiyuki
Hymenoic acid, a novel specific inhibitor of human DNA polymerase lambda from a fungus of Hymenochaetaceae sp.
Bioorganic & medicinal chemistry 2008;16(9):5115-22.
2008: Sasaki Ryohei; Suzuki Yoko; Yonezawa Yuko; Ota Yosuke; Okamoto Yoshiaki; Demizu Yusuke; Huang Peng; Yoshida Hiromi; Sugimura Kazuro; Mizushina Yoshiyuki
DNA polymerase gamma inhibition by vitamin K3 induces mitochondria-mediated cytotoxicity in human cancer cells.
Cancer science 2008;99(5):1040-8.
2008: Kimura Takuma; Nishida Masayuki; Kuramochi Kouji; Sugawara Fumio; Yoshida Hiromi; Mizushina Yoshiyuki
Novel azaphilones, kasanosins A and B, which are specific inhibitors of eukaryotic DNA polymerases beta and lambda from Talaromyces sp.
Bioorganic & medicinal chemistry 2008;16(8):4594-9.
2008: Ishimaru Chisato; Yonezawa Yuko; Kuriyama Isoko; Nishida Masayuki; Yoshida Hiromi; Mizushina Yoshiyuki
Inhibitory effects of cholesterol derivatives on DNA polymerase and topoisomerase activities, and human cancer cell growth.
Lipids 2008;43(4):373-82.
2008: Mizushina Yoshiyuki; Takeuchi Toshifumi; Takakusagi Yoichi; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Fujita Masatoshi
Inhibitory action of polyunsaturated fatty acids on Cdt1-geminin interaction.
International journal of molecular medicine 2008;21(3):281-90.
2008: Naganuma Mitsuki; Nishida Masayuki; Kuramochi Kouji; Sugawara Fumio; Yoshida Hiromi; Mizushina Yoshiyuki
1-deoxyrubralactone, a novel specific inhibitor of families X and Y of eukaryotic DNA polymerases from a fungal strain derived from sea algae.
Bioorganic & medicinal chemistry 2008;16(6):2939-44.
2008: Takahashi Shunya; Yonezawa Yuko; Kubota Akemi; Ogawa Narihito; Maeda Katsuya; Koshino Hiroyuki; Nakata Tadashi; Yoshida Hiromi; Mizushina Yoshiyuki
Pyranicin, a non-classical annonaceous acetogenin, is a potent inhibitor of DNA polymerase, topoisomerase and human cancer cell growth.
International journal of oncology 2008;32(2):451-8.
2008: Mizushina Yoshiyuki; Takeuchi Toshifumi; Takakusagi Yoichi; Yonezawa Yuko; Mizuno Takeshi; Yanagi Ken-Ichiro; Imamoto Naoko; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Fujita Masatoshi
Coenzyme Q10 as a potent compound that inhibits Cdt1-geminin interaction.
Biochimica et biophysica acta 2008;1780(2):203-13.
2008: Kuriyama Isoko; Mizuno Takeshi; Fukudome Keishi; Kuramochi Kouji; Tsubaki Kazunori; Usui Takeo; Imamoto Naoko; Sakaguchi Kengo; Sugawara Fumio; Yoshida Hiromi; Mizushina Yoshiyuki
Effect of dehydroaltenusin-C12 derivative, a selective DNA polymerase alpha inhibitor, on DNA replication in cultured cells.
Molecules (Basel, Switzerland) 2008;13(12):2948-61.
2007: Nakamura Ryoichi; Takeuchi Ryo; Kuramochi Kouji; Mizushina Yoshiyuki; Ishimaru Chisato; Takakusagi Yoichi; Takemura Masaharu; Kobayashi Susumu; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo
Chemical properties of fatty acid derivatives as inhibitors of DNA polymerases.
Organic & biomolecular chemistry 2007;5(24):3912-21.
2007: Yonezawa Yuko; Hada Takahiko; Uryu Keisuke; Tsuzuki Tsuyoshi; Nakagawa Kiyotaka; Miyazawa Teruo; Yoshida Hiromi; Mizushina Yoshiyuki
Mechanism of cell cycle arrest and apoptosis induction by conjugated eicosapentaenoic acid, which is a mammalian DNA polymerase and topoisomerase inhibitor.
International journal of oncology 2007;30(5):1197-204.
2007: Mizushina Yoshiyuki; Dairaku Issei; Yanaka Noriyuki; Takeuchi Toshifumi; Ishimaru Chisato; Sugawara Fumio; Yoshida Hiromi; Kato Norihisa
Inhibitory action of polyunsaturated fatty acids on IMP dehydrogenase.
Biochimie 2007;89(5):581-90.
2007: Kamisuki Shinji; Ishimaru Chisato; Onoda Kadohiro; Kuriyama Isoko; Ida Noriko; Sugawara Fumio; Yoshida Hiromi; Mizushina Yoshiyuki
Nodulisporol and Nodulisporone, novel specific inhibitors of human DNA polymerase lambda from a fungus, Nodulisporium sp.
Bioorganic & medicinal chemistry 2007;15(9):3109-14.
2007: Matsubara Kiminori; Saito Akiko; Tanaka Akira; Nakajima Noriyuki; Akagi Reiko; Mori Masaharu; Mizushina Yoshiyuki
Epicatechin conjugated with fatty acid is a potent inhibitor of DNA polymerase and angiogenesis.
Life sciences 2007;80(17):1578-85.
2007: Ishimaru Chisato; Kuriyama Isoko; Shimazaki Noriko; Koiwai Osamu; Sakaguchi Kengo; Kato Ikuo; Yoshida Hiromi; Mizushina Yoshiyuki
Cholesterol hemisuccinate: a selective inhibitor of family X DNA polymerases.
Biochemical and biophysical research communications 2007;354(2):619-25.
2007: Iijima Hiroshi; Kasai Nobuyuki; Chiku Hiroyuki; Takeuchi Toshifumi; Kuramochi Kouji; Hanashima Shinya; Kobayashi Susumu; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Mizushina Yoshiyuki
Structure-activity relationship of a glycolipid, sulfoquinovosyl diacylglycerol, with the DNA binding activity of p53.
International journal of molecular medicine 2007;19(1):41-8.
2007: Maeda Naoki; Kokai Yasuo; Ohtani Seiji; Sahara Hiroeki; Kuriyama Isoko; Kamisuki Shinji; Takahashi Shunya; Sakaguchi Kengo; Sugawara Fumio; Yoshida Hiromi; Sato Noriyuki; Mizushina Yoshiyuki
Anti-tumor effects of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha.
Biochemical and biophysical research communications 2007;352(2):390-6.
2007: Maeda Naoki; Kokai Yasuo; Ohtani Seiji; Sahara Hiroeki; Hada Takahiko; Ishimaru Chisato; Kuriyama Isoko; Yonezawa Yuko; Iijima Hiroshi; Yoshida Hiromi; Sato Noriyuki; Mizushina Yoshiyuki
Anti-tumor effects of the glycolipids fraction from spinach which inhibited DNA polymerase activity.
Nutrition and cancer 2007;57(2):216-23.
2007: Maeda Naoki; Hada Takahiko; Yoshida Hiromi; Mizushina Yoshiyuki
Inhibitory effect on replicative DNA polymerases, human cancer cell proliferation, and in vivo anti-tumor activity by glycolipids from spinach.
Current medicinal chemistry 2007;14(9):955-67.
2006: Murakami Shizuka; Kamisuki Shinji; Takata Kei-ichi; Kasai Nobuyuki; Kimura Seisuke; Mizushina Yoshiyuki; Ohta Keisuke; Sugawara Fumio; Sakaguchi Kengo
Site-directed mutational analysis of structural interactions of low molecule compounds binding to the N-terminal 8 kDa domain of DNA polymerase beta.
Biochemical and biophysical research communications 2006;350(1):7-16.
2006: Yonezawa Yuko; Hada Takahiko; Uryu Keisuke; Iijima Hiroshi; Yoshida Hiromi; Mizushina Yoshiyuki
Inhibitory action of C22-fatty acids on DNA polymerases and DNA topoisomerases.
International journal of molecular medicine 2006;18(4):583-8.
2006: Yonezawa Yuko; Kuriyama Isoko; Fukuoh Atsushi; Muta Tsuyoshi; Kang Dongchon; Takemura Masaharu; Kato Ikuo; Yoshida Hiromi; Mizushina Yoshiyuki
Inhibitory effect of coenzyme Q on eukaryotic DNA polymerase gamma and DNA topoisomerase II activities on the growth of a human cancer cell line.
Cancer science 2006;97(8):716-23.
2006: Iijima Hiroshi; Kasai Nobuyuki; Chiku Hiroyuki; Murakami Shizuka; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Mizushina Yoshiyuki
The inhibitory action of long-chain fatty acids on the DNA binding activity of p53.
Lipids 2006;41(6):521-7.
2006: Mizushina Yoshiyuki; Nakanishi Rumi; Kuriyama Isoko; Kamiya Kohei; Satake Toshiko; Shimazaki Noriko; Koiwai Osamu; Uchiyama Yukinobu; Yonezawa Yuko; Takemura Masaharu; Sakaguchi Kengo; Yoshida Hiromi
Beta-sitosterol-3-O-beta-D-glucopyranoside: a eukaryotic DNA polymerase lambda inhibitor.
The Journal of steroid biochemistry and molecular biology 2006;99(2-3):100-7.
2006: Kuramochi Kouji; Matsui Rie; Matsubara Yasuaki; Nakai Junko; Sunoki Takashi; Arai Satoshi; Nagata Seigo; Nagahara Yukitoshi; Mizushina Yoshiyuki; Ikekita Masahiko; Kobayashi Susumu
Apoptosis-inducing effect of epolactaene derivatives on BALL-1 cells.
Bioorganic & medicinal chemistry 2006;14(7):2151-61.
2006: Iijima Hiroshi; Musumi Keiichi; Hada Takahiko; Maeda Naoki; Yonezawa Yuko; Yoshida Hiromi; Mizushina Yoshiyuki
Inhibitory effect of monogalactosyldiacylglycerol, extracted from spinach using supercritical CO2, on mammalian DNA polymerase activity.
Journal of agricultural and food chemistry 2006;54(5):1627-32.
2006: Takeuchi Toshifumi; Ishidoh Tomomi; Iijima Hiroshi; Kuriyama Isoko; Shimazaki Noriko; Koiwai Osamu; Kuramochi Kouji; Kobayashi Susumu; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Mizushina Yoshiyuki
Structural relationship of curcumin derivatives binding to the BRCT domain of human DNA polymerase lambda.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(3):223-35.
2006: Matsubara Kiminori; Saito Akiko; Tanaka Akira; Nakajima Noriyuki; Akagi Reiko; Mori Masaharu; Mizushina Yoshiyuki
Catechin conjugated with fatty acid inhibits DNA polymerase and angiogenesis.
DNA and cell biology 2006;25(2):95-103.
2006: Mizushina Yoshiyuki; Yagita Etsuko; Kuramochi Kouji; Kuriyama Isoko; Shimazaki Noriko; Koiwai Osamu; Uchiyama Yukinobu; Yomezawa Yuko; Sugawara Fumio; Kobayashi Susumu; Sakaguchi Kengo; Yoshida Hiromi
5-(Hydroxymethyl)-2-furfural: a selective inhibitor of DNA polymerase lambda and terminal deoxynucleotidyltransferase.
Archives of biochemistry and biophysics 2006;446(1):69-76.
2006: Mizushina Yoshiyuki; Nakagawa Kiyotaka; Shibata Akira; Awata Yasutoshi; Kuriyama Isoko; Shimazaki Noriko; Koiwai Osamu; Uchiyama Yukinobu; Sakaguchi Kengo; Miyazawa Teruo; Yoshida Hiromi
Inhibitory effect of tocotrienol on eukaryotic DNA polymerase lambda and angiogenesis.
Biochemical and biophysical research communications 2006;339(3):949-55.
2006: Furukawa Tomoyuki; Nishida Masayuki; Hada Takahiko; Kuramochi Kouji; Sugawara Fumio; Kobayashi Susumu; Iijima Hiroshi; Shimada Hiroaki; Yoshida Hiromi; Mizushina Yoshiyuki
Inhibitory effect of sulfoquinovosyl diacylglycerol on prokaryotic DNA polymerase I activity and cell growth of Escherichia coli.
Journal of oleo science 2006;56(1):43-7.
2005: Mizushina Yoshiyuki; Ishidoh Tomomi; Takeuchi Toshifumi; Shimazaki Noriko; Koiwai Osamu; Kuramochi Kouji; Kobayashi Susumu; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi
Monoacetylcurcumin: a new inhibitor of eukaryotic DNA polymerase lambda and a new ligand for inhibitor-affinity chromatography.
Biochemical and biophysical research communications 2005;337(4):1288-95.
2005: Mizushina Yoshiyuki; Kasai Nobuyuki; Iijima Hiroshi; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo
Sulfo-quinovosyl-acyl-glycerol (SQAG), a eukaryotic DNA polymerase inhibitor and anti-cancer agent.
Current medicinal chemistry. Anti-cancer agents 2005;5(6):613-25.
2005: Kato Ikuo; Kuriyama Isoko; Asano Naoki; Ikeda Kyoko; Yoshida Hiromi; Mizushina Yoshiyuki
Inhibitory effect of dipeptide alcohol derivatives containing mercapto group on eukaryotic DNA polymerase alpha.
International journal of molecular medicine 2005;16(4):653-9.
2005: Kuriyama Isoko; Musumi Keiichi; Yonezawa Yuko; Takemura Masaharu; Maeda Naoki; Iijima Hiroshi; Hada Takahiko; Yoshida Hiromi; Mizushina Yoshiyuki
Inhibitory effects of glycolipids fraction from spinach on mammalian DNA polymerase activity and human cancer cell proliferation.
The Journal of nutritional biochemistry 2005;16(10):594-601.
2005: Kasai Nobuyuki; Mizushina Yoshiyuki; Murata Hiroshi; Yamazaki Takayuki; Ohkubo Tadayasu; Sakaguchi Kengo; Sugawara Fumio
Sulfoquinovosylmonoacylglycerol inhibitory mode analysis of rat DNA polymerase beta.
The FEBS journal 2005;272(17):4349-61.
2005: Mizushina Yoshiyuki; Akihisa Toshihiro; Ukiya Motohiko; Hamasaki Yusuke; Murakami-Nakai Chikako; Kuriyama Isoko; Takeuchi Toshifumi; Sugawara Fumio; Yoshida Hiromi
Structural analysis of isosteviol and related compounds as DNA polymerase and DNA topoisomerase inhibitors.
Life sciences 2005;77(17):2127-40.
2005: Mizushina Yoshiyuki; Takikawa Hirosato; Imamura Yusuke; Sasaki Mitsuru; Mori Kenji; Yoshida Hiromi
Inhibitory effect of mispyric acid on mammalian DNA polymerases.
Bioscience, biotechnology, and biochemistry 2005;69(8):1534-8.
2005: Yonezawa Yuko; Hada Takahiko; Uryu Keisuke; Tsuzuki Tsuyoshi; Eitsuka Takahiro; Miyazawa Teruo; Murakami-Nakai Chikako; Yoshida Hiromi; Mizushina Yoshiyuki
Inhibitory effect of conjugated eicosapentaenoic acid on mammalian DNA polymerase and topoisomerase activities and human cancer cell proliferation.
Biochemical pharmacology 2005;70(3):453-60.
2005: Mizushina Yoshiyuki; Saito Akiko; Tanaka Akira; Nakajima Noriyuki; Kuriyama Isoko; Takemura Masaharu; Takeuchi Toshifumi; Sugawara Fumio; Yoshida Hiromi
Structural analysis of catechin derivatives as mammalian DNA polymerase inhibitors.
Biochemical and biophysical research communications 2005;333(1):101-9.
2005: Matsubara Kiminori; Matsumoto Hiroaki; Mizushina Yoshiyuki; Mori Masaharu; Nakajima Nobuyoshi; Fuchigami Michiko; Yoshida Hiromi; Hada Takahiko
Inhibitory effect of glycolipids from spinach on in vitro and ex vivo angiogenesis.
Oncology reports 2005;14(1):157-60.
2005: Itoh Atsuko; Kumashiro Tomoko; Yamaguchi Machiko; Nagakura Naotaka; Mizushina Yoshiyuki; Nishi Toyoyuki; Tanahashi Takao
Indole alkaloids and other constituents of Rauwolfia serpentina.
Journal of natural products 2005;68(6):848-52.
2005: Mizushina Yoshiyuki; Kuramochi Kouji; Ikawa Hiroshi; Kuriyama Isoko; Shimazaki Noriko; Takemura Masaharu; Oshige Masahiko; Yoshida Hiromi; Koiwai Osamu; Sugawara Fumio; Kobayashi Susumu; Sakaguchi Kengo
Structural analysis of epolactaene derivatives as DNA polymerase inhibitors and anti-inflammatory compounds.
International journal of molecular medicine 2005;15(5):785-93.
2005: Saito Akiko; Mizushina Yoshiyuki; Ikawa Hiroshi; Yoshida Hiromi; Doi Yuki; Tanaka Akira; Nakajima Noriyuki
Systematic synthesis of galloyl-substituted procyanidin B1 and B2, and their ability of DPPH radical scavenging activity and inhibitory activity of DNA polymerases.
Bioorganic & medicinal chemistry 2005;13(8):2759-71.
2005: Kuriyama Isoko; Asano Naoki; Kato Ikuo; Ikeda Kyoko; Takemura Masaharu; Yoshida Hiromi; Sakaguchi Kengo; Mizushina Yoshiyuki
Dipeptide alcohol-based inhibitors of eukaryotic DNA polymerase alpha.
Bioorganic & medicinal chemistry 2005;13(6):2187-96.
2005: Yonezawa Yuko; Tsuzuki Tsuyoshi; Eitsuka Takahiro; Miyazawa Teruo; Hada Takahiko; Uryu Keisuke; Murakami-Nakai Chikako; Ikawa Hiroshi; Kuriyama Isoko; Takemura Masaharu; Oshige Masahiko; Yoshida Hiromi; Sakaguchi Kengo; Mizushina Yoshiyuki
Inhibitory effect of conjugated eicosapentaenoic acid on human DNA topoisomerases I and II.
Archives of biochemistry and biophysics 2005;435(1):197-206.
2005: Maeda Naoki; Hada Takahiko; Murakami-Nakai Chikako; Kuriyama Isoko; Ichikawa Hideki; Fukumori Yoshinobu; Hiratsuka Junichi; Yoshida Hiromi; Sakaguchi Kengo; Mizushina Yoshiyuki
Effects of DNA polymerase inhibitory and antitumor activities of lipase-hydrolyzed glycolipid fractions from spinach.
The Journal of nutritional biochemistry 2005;16(2):121-8.
2004: Mizushina Yoshiyuki; Tsuzuki Tsuyoshi; Eitsuka Takahiro; Miyazawa Teruo; Kobayashi Kanako; Ikawa Hiroshi; Kuriyama Isoko; Yonezawa Yuko; Takemura Masaharu; Yoshida Hiromi; Sakaguchi Kengo
Inhibitory action of conjugated C18-fatty acids on DNA polymerases and DNA topoisomerases.
Lipids 2004;39(10):977-83.
2004: Kamisuki Shinji; Takahashi Shunya; Mizushina Yoshiyuki; Sakaguchi Kengo; Nakata Tadashi; Sugawara Fumio
Precise structural elucidation of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha.
Bioorganic & medicinal chemistry 2004;12(20):5355-9.
2004: Tsuruma T; Sahara H; Takenouchi M; Yagihashi A; Iwayama Y; Shima H; Furuhata T; Torigoe T; Hanashima S; Yamazaki T; Sugawara F; Mizushina Y; Ohta K; Sakaguchi K; Sato N; Hirata K
Synthetic sulfonolipids deduced from sulfonoquinovosyl diacylglycerols of sea urchin reduces hepatic ischemia-reperfusion injury in rats.
Transplantation proceedings 2004;36(7):1965-9.
2004: Murakami-Nakai Chikako; Maeda Naoki; Yonezawa Yuko; Kuriyama Isoko; Kamisuki Shinji; Takahashi Shunya; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo; Mizushina Yoshiyuki
The effects of dehydroaltenusin, a novel mammalian DNA polymerase alpha inhibitor, on cell proliferation and cell cycle progression.
Biochimica et biophysica acta 2004;1674(2):193-9.
2004: Mizushina Yoshiyuki; Kasai Nobuyuki; Miura Katsumi; Hanashima Shinya; Takemura Masaharu; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo
Structural relationship of lithocholic acid derivatives binding to the N-terminal 8-kDa domain of DNA polymerase beta.
Biochemistry 2004;43(33):10669-77.
2004: Ogawa Akitsu; Murakami Chikako; Kamisuki Shinji; Kuriyama Isoko; Yoshida Hiromi; Sugawara Fumio; Mizushina Yoshiyuki
Pseudodeflectusin, a novel isochroman derivative from Aspergillus pseudodeflectus a parasite of the sea weed, Sargassum fusiform, as a selective human cancer cytotoxin.
Bioorganic & medicinal chemistry letters 2004;14(13):3539-43.
2004: Kuramochi Kouji; Mizushina Yoshiyuki; Nagata Seigo; Sugawara Fumio; Sakaguchi Kengo; Kobayashi Susumu
Structure-activity relationships of epolactaene analogs as DNA polymerases inhibitors.
Bioorganic & medicinal chemistry 2004;12(9):1983-9.
2004: Mizushina Yoshiyuki; Akihisa Toshihiro; Ukiya Motohiko; Murakami Chikako; Kuriyama Isoko; Xu Xianai; Yoshida Hiromi; Sakaguchi Kengo
A novel DNA topoisomerase inhibitor: dehydroebriconic acid, one of the lanostane-type triterpene acids from Poria cocos.
Cancer science 2004;95(4):354-60.
2004: Murakami Chikako; Miuzno Takeshi; Hanaoka Fumio; Yoshida Hiromi; Sakaguchi Kengo; Mizushina Yoshiyuki
Mechanism of cell cycle arrest by sulfoquinovosyl monoacylglycerol with a C18-saturated fatty acid (C18-SQMG).
Biochemical pharmacology 2004;67(7):1373-80.
2004: Kuriyama Isoko; Asano Naoki; Kato Ikuo; Oshige Masahiko; Sugino Akio; Kadota Yasuhiro; Kuchitsu Kazuyuki; Yoshida Hiromi; Sakaguchi Kengo; Mizushina Yoshiyuki
L-Homoserylaminoethanol, a novel dipeptide alcohol inhibitor of eukaryotic DNA polymerase from a plant cultured cells, Nicotina tabacum L.
Bioorganic & medicinal chemistry 2004;12(5):957-62.
2004: Akihisa Toshihiro; Mizushina Yoshiyuki; Ukiya Motohiko; Oshikubo Manabu; Kondo Seizo; Kimura Yumiko; Suzuki Takashi; Tai Takaaki
Dehydrotrametenonic acid and dehydroeburiconic acid from Poria cocos and their inhibitory effects on eukaryotic DNA polymerase alpha and beta.
Bioscience, biotechnology, and biochemistry 2004;68(2):448-50.
2004: Matsubara Kiminori; Mori Masaharu; Mizushina Yoshiyuki
Petasiphenol which inhibits DNA polymerase lambda activity is an inhibitor of in vitro angiogenesis.
Oncology reports 2004;11(2):447-51.
2003: Mizushina Yoshiyuki; Xu Xianai; Matsubara Kiminori; Murakami Chikako; Kuriyama Isoko; Oshige Masahiko; Takemura Masaharu; Kato Norihisa; Yoshida Hiromi; Sakaguchi Kengo
Pyridoxal 5'-phosphate is a selective inhibitor in vivo of DNA polymerase alpha and epsilon.
Biochemical and biophysical research communications 2003;312(4):1025-32.
2003: Mizushina Yoshiyuki; Hirota Mitsuru; Murakami Chikako; Ishidoh Tomomi; Kamisuki Shinji; Shimazaki Noriko; Takemura Masaharu; Perpelescu Marinela; Suzuki Motoshi; Yoshida Hiromi; Sugawara Fumio; Koiwai Osamu; Sakaguchi Kengo
Some anti-chronic inflammatory compounds are DNA polymerase lambda-specific inhibitors.
Biochemical pharmacology 2003;66(10):1935-44.
2003: Mizushina Yoshiyuki; Maeda Naoki; Kawasaki Miho; Ichikawa Hideki; Murakami Chikako; Takemura Masaharu; Xu Xianai; Sugawara Fumio; Fukumori Yoshinobu; Yoshida Hiromi; Sakaguchi Kengo
Inhibitory action of emulsified sulfoquinovosyl acylglycerol on mammalian DNA polymerases.
Lipids 2003;38(10):1065-74.
2003: Murakami Chikako; Takemura Masaharu; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo; Mizushina Yoshiyuki
Analysis of cell cycle regulation by 1-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride (SQMG), an inhibitor of eukaryotic DNA polymerases.
Biochemical pharmacology 2003;66(4):541-50.
2003: Mizushina Yoshiyuki; Xu Xianai; Murakami Chikako; Okano Toshio; Takemura Masaharu; Yoshida Hiromi; Sakaguchi Kengo
Selective inhibition of mammalian DNA polymerase alpha by vitamin D2 and D3.
Journal of pharmacological sciences 2003;92(3):283-90.
2003: Matsubara Kiminori; Matsumoto Hiroaki; Mizushina Yoshiyuki; Lee Jung Sup; Kato Norihisa
Inhibitory effect of pyridoxal 5'-phosphate on endothelial cell proliferation, replicative DNA polymerase and DNA topoisomerase.
International journal of molecular medicine 2003;12(1):51-5.
2003: Mizushina Yoshiyuki; Murakami Chikako; Yogi Kentaro; Ueda Katsuhiro; Ishidoh Tomomi; Takemura Masaharu; Perpelescu Marinela; Suzuki Motoshi; Oshige Masahiko; Yamaguchi Toyofumi; Saneyoshi Mineo; Yoshida Hiromi; Sakaguchi Kengo
Kohamaic acid A, a novel sesterterpenic acid, inhibits activities of DNA polymerases from deuterostomes.
Biochimica et biophysica acta 2003;1648(1-2):55-61.
2003: Mizushina Yoshiyuki; Ikuta Akira; Endoh Kenji; Oshige Masahiko; Kasai Nobuyuki; Kamiya Kohei; Satake Toshiko; Takazawa Hiroshi; Morita Hiromasa; Tomiyasu Hiroaki; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo
Inhibition of DNA polymerases and DNA topoisomerase II by triterpenes produced by plant callus.
Biochemical and biophysical research communications 2003;305(2):365-73.
2003: Mizushina Yoshiyuki; Murakami Chikako; Takikawa Hirosato; Kasai Nobuyuki; Xu Xianai; Mori Kenji; Oshige Masahiko; Yamaguchi Toyofumi; Saneyoshi Mineo; Shimazaki Noriko; Koiwai Osamu; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo
Molecular action mode of Hippospongic acid A, an inhibitor of gastrulation of starfish embryos.
Journal of biochemistry 2003;133(4):541-52.
2003: Mizushina Yoshiyuki; Xu Xianai; Asano Naoki; Kasai Nobuyuki; Kato Atsushi; Takemura Masaharu; Asahara Hitomi; Linn Stuart; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo
The inhibitory action of pyrrolidine alkaloid, 1,4-dideoxy-1,4-imino-D-ribitol, on eukaryotic DNA polymerases.
Biochemical and biophysical research communications 2003;304(1):78-85.
2003: Mizushina Yoshiyuki; Ishidoh Tomomi; Kamisuki Shinji; Nakazawa Satoshi; Takemura Masaharu; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo
Flavonoid glycoside: a new inhibitor of eukaryotic DNA polymerase alpha and a new carrier for inhibitor-affinity chromatography.
Biochemical and biophysical research communications 2003;301(2):480-7.
2003: Mizushina Yoshiyuki; Xu Xianai; Asahara Hitomi; Takeuchi Ryo; Oshige Masahiko; Shimazaki Noriko; Takemura Masaharu; Yamaguchi Toyofumi; Kuroda Kazufumi; Linn Stuart; Yoshida Hiromi; Koiwai Osamu; Saneyoshi Mineo; Sugawara Fumio; Sakaguchi Kengo
A sulphoquinovosyl diacylglycerol is a DNA polymerase epsilon inhibitor.
The Biochemical journal 2003;370(Pt 1):299-305.
2003: Murakami Chikako; Yamazaki Takayuki; Hanashima Shinya; Takahashi Shunya; Takemura Masaharu; Yoshida Shonen; Ohta Keisuke; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo; Mizushina Yoshiyuki
A novel DNA polymerase inhibitor and a potent apoptosis inducer: 2-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride with stearic acid.
Biochimica et biophysica acta 2003;1645(1):72-80.
2003: Murakami Chikako; Kumagai Taeko; Hada Takahiko; Kanekazu Ui; Nakazawa Satoshi; Kamisuki Shinji; Maeda Naoki; Xu Xianai; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo; Mizushina Yoshiyuki
Effects of glycolipids from spinach on mammalian DNA polymerases.
Biochemical pharmacology 2003;65(2):259-67.
2002: Mizushina Yoshiyuki; Kamisuki Shinji; Kasai Nobuyuki; Ishidoh Tomomi; Shimazaki Noriko; Takemura Masaharu; Asahara Hitomi; Linn Stuart; Yoshida Shonen; Koiwai Osamu; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo
Petasiphenol: a DNA polymerase lambda inhibitor.
Biochemistry 2002;41(49):14463-71.
2002: Kasai Nobuyuki; Mizushina Yoshiyuki; Sugawara Fumio; Sakaguchi Kengo
Three-dimensional structural model analysis of the binding site of an inhibitor, nervonic acid, of both DNA polymerase beta and HIV-1 reverse transcriptase.
Journal of biochemistry 2002;132(5):819-28.
2002: Oda Masako; Ueno Takamasa; Kasai Nobuyuki; Takahashi Hirotada; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo; Hayashi Hideya; Mizushina Yoshiyuki
Inhibition of telomerase by linear-chain fatty acids: a structural analysis.
The Biochemical journal 2002;367(Pt 2):329-34.
2002: Matsumoto Yoshitaka; Sahara Hiroeki; Fujita Tatsuya; Shimozawa Kumiko; Takenouchi Mika; Torigoe Toshihiko; Hanashima Shinya; Yamazaki Takeyuki; Takahashi Shunya; Sugawara Fumio; Mizushina Yoshiyuki; Ohta Keisuke; Takahashi Nobuaki; Gasa Shinsei; Jimbow Kouichi; Sakaguchi Kengo; Sato Noriyuki
An immunosuppressive effect by synthetic sulfonolipids deduced from sulfonoquinovosyl diacylglycerols of sea urchin.
Transplantation 2002;74(2):261-7.
2002: Murakami Chikako; Yamazaki Takayuki; Hanashima Shinya; Takahashi Shunya; Ohta Keisuke; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo; Mizushina Yoshiyuki
Structure-function relationship of synthetic sulfoquinovosyl-acylglycerols as mammalian DNA polymerase inhibitors.
Archives of biochemistry and biophysics 2002;403(2):229-36.
2002: Mizushina Yoshiyuki; Kasai Nobuyuki; Sugawara Fumio; Sakaguchi Kengo
[Structural homology between molecular probes binding site of DNA polymerase beta and DNA topoisomerase II]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2002;47(6):708-14.
2002: Murakami Chikako; Ishijima Kiyomi; Hirota Mitsuru; Sakaguchi Kengo; Yoshida Hiromi; Mizushina Yoshiyuki
Novel anti-inflammatory compounds from Rubus sieboldii, triterpenoids, are inhibitors of mammalian DNA polymerases.
Biochimica et biophysica acta 2002;1596(2):193-200.
2002: Sakaguchi Kengo; Sugawara Fumio; Mizushina Yoshiyuki
[Inhibitors of eukaryotic DNA polymerases]
Seikagaku. The Journal of Japanese Biochemical Society 2002;74(3):244-51.
2002: Murakami Chikako; Takemura Masaharu; Sugiyama Yuichi; Kamisuki Shinji; Asahara Hitomi; Kawasaki Miho; Ishidoh Tomomi; Linn Stuart; Yoshida Shonen; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo; Mizushina Yoshiyuki
Vitamin A-related compounds, all-trans retinal and retinoic acids, selectively inhibit activities of mammalian replicative DNA polymerases.
Biochimica et biophysica acta 2002;1574(1):85-92.
2002: Kamisuki Shinji; Murakami Chikako; Ohta Keisuke; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo; Mizushina Yoshiyuki
Actions of derivatives of dehydroaltenusin, a new mammalian DNA polymerase alpha-specific inhibitor.
Biochemical pharmacology 2002;63(3):421-7.
2002: Mizushina Yoshiyuki; Murakami Chikako; Ohta Keisuke; Takikawa Hirosato; Mori Kenji; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo
Selective inhibition of the activities of both eukaryotic DNA polymerases and DNA topoisomerases by elenic acid.
Biochemical pharmacology 2002;63(3):399-407.
2002: Watanabe Madoka; Hanashima Shinya; Mizushina Yoshiyuki; Yoshida Hiromi; Oshige Masahiko; Sakaguchi Kengo; Sugawara Fumio
Biotinylated lithocholic acids for affinity chromatography of mammalian DNA polymerases alpha and beta.
Bioorganic & medicinal chemistry letters 2002;12(3):287-90.
2002: Sahara Hiroeki; Hanashima Shinya; Yamazaki Takayuki; Takahashi Shunya; Sugawara Fumio; Ohtani Seiji; Ishikawa Masako; Mizushina Yoshiyuki; Ohta Keisuke; Shimozawa Kumiko; Gasa Shinsei; Jimbow Kouichi; Sakaguchi Kengo; Sato Noriyuki; Takahashi Nobuaki
Anti-tumor effect of chemically synthesized sulfolipids based on sea urchin's natural sulfonoquinovosylmonoacylglycerols.
Japanese journal of cancer research : Gann 2002;93(1):85-92.
2002: Mizushina Yoshiyuki; Kamisuki Shinji; Kasai Nobuyuki; Shimazaki Noriko; Takemura Masaharu; Asahara Hitomi; Linn Stuart; Yoshida Shonen; Matsukage Akio; Koiwai Osamu; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo
A plant phytotoxin, solanapyrone A, is an inhibitor of DNA polymerase beta and lambda.
The Journal of biological chemistry 2002;277(1):630-8.
2001: Ohta K; Mizushina Y; Yamazaki T; Hanashima S; Sugawara F; Sakaguchi K
Specific interaction between an oligosaccharide on the tumor cell surface and the novel antitumor agents, sulfoquinovosylacylglycerols.
Biochemical and biophysical research communications 2001;288(4):893-900.
2001: Mizushina Y; Kasai N; Sugawara F; Iida A; Yoshida H; Sakaguchi K
Three-dimensional structural model analysis of the binding site of lithocholic acid, an inhibitor of DNA polymerase beta and DNA topoisomerase II.
Journal of biochemistry 2001;130(5):657-64.
2001: Mizushina Y; Sugiyama Y; Yoshida H; Hanashima S; Yamazaki T; Kamisuki S; Ohta K; Takemura M; Yamaguchi T; Matsukage A; Yoshida S; Saneyoshi M; Sugawara F; Sakagauchi K
Galactosyldiacylglycerol, a mammalian DNA polymerase alpha-specific inhibitor from a sea alga, Petalonia bingbamiae.
Biological & pharmaceutical bulletin 2001;24(9):982-7.
2001: Hanashima S; Mizushina Y; Yamazaki T; Ohta K; Takahashi S; Sahara H; Sakaguchi K; Sugawar F
Synthesis of sulfoquinovosylacylglycerols, inhibitors of eukaryotic DNA polymerase alpha and beta.
Bioorganic & medicinal chemistry 2001;9(2):367-76.
2000: Mizushina Y; Sugawara F; Iida A; Sakaguchi K
Structural homology between DNA binding sites of DNA polymerase beta and DNA topoisomerase II.
Journal of molecular biology 2000;304(3):385-95.
2000: Matsumoto Y; Sahara H; Fujita T; Hanashima S; Yamazaki T; Takahashi S; Sugawara F; Mizushina Y; Ohta K; Takahashi N; Jimbow K; Sakaguchi K; Sato N
A novel immunosuppressive agent, SQDG, derived from sea urchin.
Transplantation proceedings 2000;32(7):2051-3.
2000: Hanashima S; Mizushina Y; Ohta K; Yamazaki T; Sugawara F; Sakaguchi K
Structure-activity relationship of a novel group of mammalian DNA polymerase inhibitors, synthetic sulfoquinovosylacylglycerols.
Japanese journal of cancer research : Gann 2000;91(10):1073-83.
2000: Mizushina Y; Ueno T; Oda M; Yamaguchi T; Saneyoshi M; Sakaguchi K
The biochemical mode of inhibition of DNA polymerase beta by alpha-rubromycin.
Biochimica et biophysica acta 2000;1523(2-3):172-81.
2000: Mizushina Y; Ohkubo T; Sugawara F; Sakaguchi K
Structure of lithocholic acid binding to the N-terminal 8-kDa domain of DNA polymerase beta.
Biochemistry 2000;39(41):12606-13.
2000: Mizushina Y; Kamisuki S; Mizuno T; Takemura M; Asahara H; Linn S; Yamaguchi T; Matsukage A; Hanaoka F; Yoshida S; Saneyoshi M; Sugawara F; Sakaguchi K
Dehydroaltenusin, a mammalian DNA polymerase alpha inhibitor.
The Journal of biological chemistry 2000;275(43):33957-61.
2000: Mizushina Y; Iida A; Ohta K; Sugawara F; Sakaguchi K
Novel triterpenoids inhibit both DNA polymerase and DNA topoisomerase.
The Biochemical journal 2000;350 Pt 3():757-63.
2000: Mizushina Y; Sagisaka M; Sakaib H; Abeb M; Sakaguchi K
Mode analysis of binding of fatty acids to mammalian DNA polymerases.
Biochimica et biophysica acta 2000;1486(2-3):211-8.
2000: Mizushina Y; Kobayashi S; Kuramochi K; Nagata S; Sugawara F; Sakaguchi K
Epolactaene, a novel neuritogenic compound in human neuroblastoma cells, selectively inhibits the activities of mammalian DNA polymerases and human DNA topoisomerase II.
Biochemical and biophysical research communications 2000;273(2):784-8.
2000: Mizushina Y; Miyazaki S; Ohta K; Hirota M; Sakaguchi K
Novel anti-inflammatory compounds from Myrsine seguinii, terpeno-benzoic acids, are inhibitors of mammalian DNA polymerases.
Biochimica et biophysica acta 2000;1475(1):1-4.
2000: Ohta K; Hanashima S; Mizushina Y; Yamazaki T; Saneyoshi M; Sugawara F; Sakaguchi K
Studies on a novel DNA polymerase inhibitor group, synthetic sulfoquinovosylacylglycerols: inhibitory action on cell proliferation.
Mutation research 2000;467(2):139-52.
1999: Mizushina Y; Takahashi N; Hanashima L; Koshino H; Esumi Y; Uzawa J; Sugawara F; Sakaguchi K
Lucidenic acid O and lactone, new terpene inhibitors of eukaryotic DNA polymerases from a basidiomycete, Ganoderma lucidum.
Bioorganic & medicinal chemistry 1999;7(9):2047-52.
1999: Mizushina Y; Ohkubo T; Date T; Yamaguchi T; Saneyoshi M; Sugawara F; Sakaguchi K
Mode analysis of a fatty acid molecule binding to the N-terminal 8-kDa domain of DNA polymerase beta. A 1:1 complex and binding surface.
The Journal of biological chemistry 1999;274(36):25599-607.
1999: Mizushina Y; Takahashi N; Ogawa A; Tsurugaya K; Koshino H; Takemura M; Yoshida S; Matsukage A; Sugawara F; Sakaguchi K
The cyanogenic glucoside, prunasin (D-mandelonitrile-beta-D-glucoside), is a novel inhibitor of DNA polymerase beta.
Journal of biochemistry 1999;126(2):430-6.
1999: Ohta K; Mizushina Y; Hirata N; Takemura M; Sugawara F; Matsukage A; Yoshida S; Sakaguchi K
Action of a new mammalian DNA polymerase inhibitor, sulfoquinovosyldiacylglycerol.
Biological & pharmaceutical bulletin 1999;22(2):111-6.
1998: Mizushina Y; Ueno T; Goto Y; Isobe Y; Sako M; Fujita T; Hirota K; Hayashi H; Sakaguchi K
Carboxyflavins, novel inhibitors of Taq DNA polymerase.
International journal of molecular medicine 1998;2(3):283-6.
1998: Togashi H; Mizushina Y; Takemura M; Sugawara F; Koshino H; Esumi Y; Uzawa J; Kumagai H; Matsukage A; Yoshida S; Sakaguchi K
4-Hydroxy-17-methylincisterol, an inhibitor of DNA polymerase-alpha activity and the growth of human cancer cells in vitro.
Biochemical pharmacology 1998;56(5):583-90.
1998: Mizushina Y; Hanashima L; Yamaguchi T; Takemura M; Sugawara F; Saneyoshi M; Matsukage A; Yoshida S; Sakaguchi K
A mushroom fruiting body-inducing substance inhibits activities of replicative DNA polymerases.
Biochemical and biophysical research communications 1998;249(1):17-22.
1998: Seto H; Hatanaka M; Kimura S; Oshige M; Tsuya Y; Mizushina Y; Sawado T; Aoyagi N; Matsumoto T; Hashimoto J; Sakaguchi K
Purification and characterization of a 100 kDa DNA polymerase from cauliflower inflorescence.
The Biochemical journal 1998;332 ( Pt 2)():557-63.
1998: Mizushina Y; Watanabe I; Togashi H; Hanashima L; Takemura M; Ohta K; Sugawara F; Koshino H; Esumi Y; Uzawa J; Matsukage A; Yoshida S; Sakaguchi K
An ergosterol peroxide, a natural product that selectively enhances the inhibitory effect of linoleic acid on DNA polymerase beta.
Biological & pharmaceutical bulletin 1998;21(5):444-8.
1998: Mizushina Y; Matsukage A; Sakaguchi K
The biochemical inhibition mode of bredinin-5'-monophosphate on DNA polymerase beta.
Biochimica et biophysica acta 1998;1403(1):5-11.
1998: Ohta K; Mizushina Y; Hirata N; Takemura M; Sugawara F; Matsukage A; Yoshida S; Sakaguchi K
Sulfoquinovosyldiacylglycerol, KM043, a new potent inhibitor of eukaryotic DNA polymerases and HIV-reverse transcriptase type 1 from a marine red alga, Gigartina tenella.
Chemical & pharmaceutical bulletin 1998;46(4):684-6.
1998: Mizushina Y; Tanaka N; Kitamura A; Tamai K; Ikeda M; Takemura M; Sugawara F; Arai T; Matsukage A; Yoshida S; Sakaguchi K
The inhibitory effect of novel triterpenoid compounds, fomitellic acids, on DNA polymerase beta.
The Biochemical journal 1998;330 ( Pt 3)():1325-32.
1998: Mizushina Y; Watanabe I; Ohta K; Takemura M; Sahara H; Takahashi N; Gasa S; Sugawara F; Matsukage A; Yoshida S; Sakaguchi K
Studies on inhibitors of mammalian DNA polymerase alpha and beta: sulfolipids from a pteridophyte, Athyrium niponicum.
Biochemical pharmacology 1998;55(4):537-41.
1998: Tanaka N; Kitamura A; Mizushina Y; Sugawara F; Sakaguchi K
Fomitellic acids, triterpenoid inhibitors of eukaryotic DNA polymerases from a basidiomycete, Fomitella fraxinea.
Journal of natural products 1998;61(2):193-7.
1998: Horie T; Mizushina Y; Takemura M; Sugawara F; Matsukage A; Yoshida S; Sakaguchi K
A 5'-monophosphate form of bredinin selectively inhibits the activities of mammalian DNA polymerases in vitro.
International journal of molecular medicine 1998;1(1):83-90.
1997: Mizushina Y; Yoshida S; Matsukage A; Sakaguchi K
The inhibitory action of fatty acids on DNA polymerase beta.
Biochimica et biophysica acta 1997;1336(3):509-21.
1996: Mizushina Y; Tanaka N; Yagi H; Kurosawa T; Onoue M; Seto H; Horie T; Aoyagi N; Yamaoka M; Matsukage A; Yoshida S; Sakaguchi K
Fatty acids selectively inhibit eukaryotic DNA polymerase activities in vitro.
Biochimica et biophysica acta 1996;1308(3):256-62.
1996: Mizushina Y; Yagi H; Tanaka N; Kurosawa T; Seto H; Katsumi K; Onoue M; Ishida H; Iseki A; Nara T; Morohashi K; Horie T; Onomura Y; Narusawa M; Aoyagi N; Takami K; Yamaoka M; Inoue Y; Matsukage A; Yoshida S; Sakaguchi K
Screening of inhibitor of eukaryotic DNA polymerases produced by microorganisms.
The Journal of antibiotics 1996;49(5):491-2.

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