Danesh Moazed

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TOP 3
Moazed Danesh
Molecular biology. Rejoice--RNAi for yeast.
Halic Mario; Moazed Danesh
22G-RNAs in transposon silencing and centromere function.
Johnson Aaron; Li Geng; Sikorski Timothy W; Buratowski Stephen; Woodcock Christopher L; Moazed Danesh
Reconstitution of heterochromatin-dependent transcriptional gene silencing.

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All Publications

2009: Moazed Danesh
Molecular biology. Rejoice--RNAi for yeast.
Science (New York, N.Y.) 2009;326(5952):533-4.
2009: Halic Mario; Moazed Danesh
22G-RNAs in transposon silencing and centromere function.
Molecular cell 2009;36(2):170-1.
2009: Johnson Aaron; Li Geng; Sikorski Timothy W; Buratowski Stephen; Woodcock Christopher L; Moazed Danesh
Reconstitution of heterochromatin-dependent transcriptional gene silencing.
Molecular cell 2009;35(6):769-81.
2009: Sinha Manisha; Watanabe Shinya; Johnson Aaron; Moazed Danesh; Peterson Craig L
Recombinational repair within heterochromatin requires ATP-dependent chromatin remodeling.
Cell 2009;138(6):1109-21.
2009: Halic Mario; Moazed Danesh
Transposon silencing by piRNAs.
Cell 2009;138(6):1058-60.
2009: Li Haitao; Motamedi Mohammad R; Yip Calvin K; Wang Zhanxin; Walz Thomas; Patel Dinshaw J; Moazed Danesh
An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Molecular cell 2009;34(2):155-67.
2009: Tomson Brett N; Rahal Rami; Reiser Vladimír; Monje-Casas Fernando; Mekhail Karim; Moazed Danesh; Amon Angelika
Regulation of Spo12 phosphorylation and its essential role in the FEAR network.
Current biology : CB 2009;19(6):449-60.
2009: Moazed Danesh
Small RNAs in transcriptional gene silencing and genome defence.
Nature 2009;457(7228):413-20.
2008: Motamedi Mohammad R; Hong Eun-Jin Erica; Li Xue; Gerber Scott; Denison Carilee; Gygi Steven; Moazed Danesh
HP1 proteins form distinct complexes and mediate heterochromatic gene silencing by nonoverlapping mechanisms.
Molecular cell 2008;32(6):778-90.
2008: Mekhail Karim; Seebacher Jan; Gygi Steven P; Moazed Danesh
Role for perinuclear chromosome tethering in maintenance of genome stability.
Nature 2008;456(7222):667-70.
2008: Buchberger Johannes R; Onishi Megumi; Li Geng; Seebacher Jan; Rudner Adam D; Gygi Steven P; Moazed Danesh
Sir3-nucleosome interactions in spreading of silent chromatin in Saccharomyces cerevisiae.
Molecular and cellular biology 2008;28(22):6903-18.
2008: Madhani Hiten D; Francis Nicole J; Kingston Robert E; Kornberg Roger D; Moazed Danesh; Narlikar Geeta J; Panning Barbara; Struhl Kevin
Epigenomics: a roadmap, but to where?
Science (New York, N.Y.) 2008;322(5898):43-4.
2008: Bühler Marc; Spies Noah; Bartel David P; Moazed Danesh
TRAMP-mediated RNA surveillance prevents spurious entry of RNAs into the Schizosaccharomyces pombe siRNA pathway.
Nature structural & molecular biology 2008;15(10):1015-23.
2008: Iida Tetsushi; Nakayama Jun-ichi; Moazed Danesh
siRNA-mediated heterochromatin establishment requires HP1 and is associated with antisense transcription.
Molecular cell 2008;31(2):178-89.
2008: Kanfi Yariv; Shalman Ronnie; Peshti Victoria; Pilosof Shmuel N; Gozlan Yosi M; Pearson Kevin J; Lerrer Batya; Moazed Danesh; Marine Jean-Christophe; de Cabo Rafael; Cohen Haim Y
Regulation of SIRT6 protein levels by nutrient availability.
FEBS letters 2008;582(5):543-8.
2007: Onishi Megumi; Liou Gunn-Guang; Buchberger Johannes R; Walz Thomas; Moazed Danesh
Role of the conserved Sir3-BAH domain in nucleosome binding and silent chromatin assembly.
Molecular cell 2007;28(6):1015-28.
2007: Colmenares Serafin U; Buker Shane M; Buhler Marc; Dlakic Mensur; Moazed Danesh
Coupling of double-stranded RNA synthesis and siRNA generation in fission yeast RNAi.
Molecular cell 2007;27(3):449-61.
2007: Niu Hengyao; Li Xue; Job Emily; Park Caroline; Moazed Danesh; Gygi Steven P; Hollingsworth Nancy M
Mek1 kinase is regulated to suppress double-strand break repair between sister chromatids during budding yeast meiosis.
Molecular and cellular biology 2007;27(15):5456-67.
2007: Skiniotis Georgios; Moazed Danesh; Walz Thomas
Acetylated histone tail peptides induce structural rearrangements in the RSC chromatin remodeling complex.
The Journal of biological chemistry 2007;282(29):20804-8.
2007: Bühler Marc; Haas Wilhelm; Gygi Steven P; Moazed Danesh
RNAi-dependent and -independent RNA turnover mechanisms contribute to heterochromatic gene silencing.
Cell 2007;129(4):707-21.
2007: Lan Fei; Zaratiegui Mikel; Villén Judit; Vaughn Matthew W; Verdel André; Huarte Maite; Shi Yujiang; Gygi Steven P; Moazed Danesh; Martienssen Robert A; Shi Yang
S. pombe LSD1 homologs regulate heterochromatin propagation and euchromatic gene transcription.
Molecular cell 2007;26(1):89-101.
2007: Buker Shane M; Iida Tetsushi; Bühler Marc; Villén Judit; Gygi Steven P; Nakayama Jun-Ichi; Moazed Danesh
Two different Argonaute complexes are required for siRNA generation and heterochromatin assembly in fission yeast.
Nature structural & molecular biology 2007;14(3):200-7.
2007: Morris Corey A; Moazed Danesh
Centromere assembly and propagation.
Cell 2007;128(4):647-50.
2006: Huang Julie; Brito Ilana L; Villén Judit; Gygi Steven P; Amon Angelika; Moazed Danesh
Inhibition of homologous recombination by a cohesin-associated clamp complex recruited to the rDNA recombination enhancer.
Genes & development 2006;20(20):2887-901.
2006: Matecic Mirela; Martins-Taylor Kristen; Hickman Merrit; Tanny Jason; Moazed Danesh; Holmes Scott G
New alleles of SIR2 define cell-cycle-specific silencing functions.
Genetics 2006;173(4):1939-50.
2006: Bühler Marc; Verdel André; Moazed Danesh
Tethering RITS to a nascent transcript initiates RNAi- and heterochromatin-dependent gene silencing.
Cell 2006;125(5):873-86.
2006: Huang Julie; Moazed Danesh
Sister chromatid cohesion in silent chromatin: each sister to her own ring.
Genes & development 2006;20(2):132-7.
2006: Moazed D; Bühler M; Buker S M; Colmenares S U; Gerace E L; Gerber S A; Hong E-J E; Motamedi M R; Verdel A; Villén J; Gygi S P
Studies on the mechanism of RNAi-dependent heterochromatin assembly.
Cold Spring Harbor symposia on quantitative biology 2006;71():461-71.
2005: Verdel André; Moazed Danesh
RNAi-directed assembly of heterochromatin in fission yeast.
FEBS letters 2005;579(26):5872-8.
2005: Hong Eun-Jin Erica; Villén Judit; Gerace Erica L; Gygi Steven P; Moazed Danesh
A cullin E3 ubiquitin ligase complex associates with Rik1 and the Clr4 histone H3-K9 methyltransferase and is required for RNAi-mediated heterochromatin formation.
RNA biology 2005;2(3):106-11.
2005: Buratowski Stephen; Moazed Danesh
Gene regulation: expression and silencing coupled.
Nature 2005;435(7046):1174-5.
2005: Rudner Adam D; Hall Brian E; Ellenberger Tom; Moazed Danesh
A nonhistone protein-protein interaction required for assembly of the SIR complex and silent chromatin.
Molecular and cellular biology 2005;25(11):4514-28.
2005: Liou Gunn-Guang; Tanny Jason C; Kruger Ryan G; Walz Thomas; Moazed Danesh
Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation.
Cell 2005;121(4):515-27.
2005: Denison Carilee; Rudner Adam D; Gerber Scott A; Bakalarski Corey E; Moazed Danesh; Gygi Steven P
A proteomic strategy for gaining insights into protein sumoylation in yeast.
Molecular & cellular proteomics : MCP 2005;4(3):246-54.
2005: Sugiyama Tomoyasu; Cam Hugh; Verdel André; Moazed Danesh; Grewal Shiv I S
RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(1):152-7.
2005: Verdel André; Moazed Danesh
Labeling and characterization of small RNAs associated with the RNA interference effector complex RITS.
Methods in enzymology 2005;392():297-307.
2004: Motamedi Mohammad R; Verdel André; Colmenares Serafin U; Gerber Scott A; Gygi Steven P; Moazed Danesh
Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs.
Cell 2004;119(6):789-802.
2004: Noma Ken-ichi; Sugiyama Tomoyasu; Cam Hugh; Verdel Andre; Zofall Martin; Jia Songtao; Moazed Danesh; Grewal Shiv I S
RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing.
Nature genetics 2004;36(11):1174-80.
2004: Tanny Jason C; Kirkpatrick Donald S; Gerber Scott A; Gygi Steven P; Moazed Danesh
Budding yeast silencing complexes and regulation of Sir2 activity by protein-protein interactions.
Molecular and cellular biology 2004;24(16):6931-46.
2004: Stegmeier Frank; Huang Julie; Rahal Rami; Zmolik Jessica; Moazed Danesh; Amon Angelika
The replication fork block protein Fob1 functions as a negative regulator of the FEAR network.
Current biology : CB 2004;14(6):467-80.
2004: Verdel André; Jia Songtao; Gerber Scott; Sugiyama Tomoyasu; Gygi Steven; Grewal Shiv I S; Moazed Danesh
RNAi-mediated targeting of heterochromatin by the RITS complex.
Science (New York, N.Y.) 2004;303(5658):672-6.
2004: Moazed Danesh; Rudner Adam D; Huang Julie; Hoppe Georg J; Tanny Jason C
A model for step-wise assembly of heterochromatin in yeast.
Novartis Foundation symposium 2004;259():48-56; discussion 56-62, 163-9.
2003: Huang Julie; Moazed Danesh
Association of the RENT complex with nontranscribed and coding regions of rDNA and a regional requirement for the replication fork block protein Fob1 in rDNA silencing.
Genes & development 2003;17(17):2162-76.
2003: Grewal Shiv I S; Moazed Danesh
Heterochromatin and epigenetic control of gene expression.
Science (New York, N.Y.) 2003;301(5634):798-802.
2003: Shankaranarayana Gurumurthy D; Motamedi Mohammad R; Moazed Danesh; Grewal Shiv I S
Sir2 regulates histone H3 lysine 9 methylation and heterochromatin assembly in fission yeast.
Current biology : CB 2003;13(14):1240-6.
2003: Chang Ju-Fang; Hall Brian E; Tanny Jason C; Moazed Danesh; Filman David; Ellenberger Tom
Structure of the coiled-coil dimerization motif of Sir4 and its interaction with Sir3.
Structure (London, England : 1993) 2003;11(6):637-49.
2002: Li Jiaxu; Moazed Danesh; Gygi Steven P
Association of the histone methyltransferase Set2 with RNA polymerase II plays a role in transcription elongation.
The Journal of biological chemistry 2002;277(51):49383-8.
2002: Tanny Jason C; Moazed Danesh
Recognition of acetylated proteins: lessons from an ancient family of enzymes.
Structure (London, England : 1993) 2002;10(10):1290-2.
2002: Hoppe Georg J; Tanny Jason C; Rudner Adam D; Gerber Scott A; Danaie Sherwin; Gygi Steven P; Moazed Danesh
Steps in assembly of silent chromatin in yeast: Sir3-independent binding of a Sir2/Sir4 complex to silencers and role for Sir2-dependent deacetylation.
Molecular and cellular biology 2002;22(12):4167-80.
2002: Kellogg Douglas R; Moazed Danesh
Protein- and immunoaffinity purification of multiprotein complexes.
Methods in enzymology 2002;351():172-83.
2001: Moazed D
Common themes in mechanisms of gene silencing.
Molecular cell 2001;8(3):489-98.
2001: Shou W; Sakamoto K M; Keener J; Morimoto K W; Traverso E E; Azzam R; Hoppe G J; Feldman R M; DeModena J; Moazed D; Charbonneau H; Nomura M; Deshaies R J
Net1 stimulates RNA polymerase I transcription and regulates nucleolar structure independently of controlling mitotic exit.
Molecular cell 2001;8(1):45-55.
2001: Moazed D
Enzymatic activities of Sir2 and chromatin silencing.
Current opinion in cell biology 2001;13(2):232-8.
2001: Tanny J C; Moazed D
Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(2):415-20.
1999: Tanny J C; Dowd G J; Huang J; Hilz H; Moazed D
An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing.
Cell 1999;99(7):735-45.
1999: Straight A F; Shou W; Dowd G J; Turck C W; Deshaies R J; Johnson A D; Moazed D
Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity.
Cell 1999;97(2):245-56.
1999: Shou W; Seol J H; Shevchenko A; Baskerville C; Moazed D; Chen Z W; Jang J; Shevchenko A; Charbonneau H; Deshaies R J
Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex.
Cell 1999;97(2):233-44.
1999: Merryman C; Moazed D; Daubresse G; Noller H F
Nucleotides in 23S rRNA protected by the association of 30S and 50S ribosomal subunits.
Journal of molecular biology 1999;285(1):107-13.
1999: Merryman C; Moazed D; McWhirter J; Noller H F
Nucleotides in 16S rRNA protected by the association of 30S and 50S ribosomal subunits.
Journal of molecular biology 1999;285(1):97-105.
1996: Moazed D; Johnson D
A deubiquitinating enzyme interacts with SIR4 and regulates silencing in S. cerevisiae.
Cell 1996;86(4):667-77.
1995: Moazed D; Samaha R R; Gualerzi C; Noller H F
Specific protection of 16 S rRNA by translational initiation factors.
Journal of molecular biology 1995;248(2):207-10.
1991: Moazed D; Noller H F
Sites of interaction of the CCA end of peptidyl-tRNA with 23S rRNA.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(9):3725-8.
1990: Moazed D; Noller H F
Binding of tRNA to the ribosomal A and P sites protects two distinct sets of nucleotides in 16 S rRNA.
Journal of molecular biology 1990;211(1):135-45.
1989: Moazed D; Noller H F
Intermediate states in the movement of transfer RNA in the ribosome.
Nature 1989;342(6246):142-8.
1989: Moazed D; Noller H F
Interaction of tRNA with 23S rRNA in the ribosomal A, P, and E sites.
Cell 1989;57(4):585-97.
1988: Moazed D; Robertson J M; Noller H F
Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA.
Nature 1988;334(6180):362-4.
1987: Moazed D; Noller H F
Chloramphenicol, erythromycin, carbomycin and vernamycin B protect overlapping sites in the peptidyl transferase region of 23S ribosomal RNA.
Biochimie 1987;69(8):879-84.
1987: Noller H F; Stern S; Moazed D; Powers T; Svensson P; Changchien L M
Studies on the architecture and function of 16S rRNA.
Cold Spring Harbor symposia on quantitative biology 1987;52():695-708.

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Danesh Moazed

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