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Danesh Moazed

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TOP 3
Feng Wang; Mohammed Altaf; Mark A Currie; Aaron Johnson; Geng Li; Chenning Lu; Danesh Moazed
Heterochromatin protein Sir3 induces contacts between the amino terminus of histone H4 and nucleosomal DNA.
Danesh Moazed
Chromatin: a tail of repression.
Danesh Moazed
A piRNA to remember.

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All Publications

2013: Feng Wang; Mohammed Altaf; Mark A Currie; Aaron Johnson; Geng Li; Chenning Lu; Danesh Moazed
Heterochromatin protein Sir3 induces contacts between the amino terminus of histone H4 and nucleosomal DNA.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(21):8495-500.
2013: Danesh Moazed
Chromatin: a tail of repression.
Current biology : CB 2013;23(10):R456-9.
2012: Danesh Moazed
A piRNA to remember.
Cell 2012;149(3):512-4.
2012: Daniel Holoch; Danesh Moazed
RNAi in fission yeast finds new targets and new ways of targeting at the nuclear periphery.
Genes & development 2012;26(8):741-5.
2012: Shu-Yun Tung; Thomas Walz; Jia-Yang Hong; Danesh Moazed; Gunn-Guang Liou
Chromatin affinity-precipitation using a small metabolic molecule: its application to analysis of O-acetyl-ADP-ribose.
Cellular and molecular life sciences : CMLS 2012;69(4):641-50.
2011: Danesh Moazed
Mechanisms for the inheritance of chromatin states.
Cell 2011;146(4):510-8.
2011: Monika Gullerova; Danesh Moazed; Nick J Proudfoot
Autoregulation of convergent RNAi genes in fission yeast.
Genes & development 2011;25(6):556-68.
2010: Erica L Gerace; Danesh Moazed
Histone demethylation and timely DNA replication.
Molecular cell 2010;40(5):683-4.
2010: Erica L Gerace; Mario Halic; Danesh Moazed
The methyltransferase activity of Clr4Suv39h triggers RNAi independently of histone H3K9 methylation.
Molecular cell 2010;39(3):360-72.
2010: Mario Halic; Danesh Moazed
Dicer-independent primal RNAs trigger RNAi and heterochromatin formation.
Cell 2010;140(4):504-16.
2009: Danesh Moazed
Molecular biology. Rejoice--RNAi for yeast.
Science (New York, N.Y.) 2009;326(5952):533-4.
2009: Mario Halic; Danesh Moazed
22G-RNAs in transposon silencing and centromere function.
Molecular cell 2009;36(2):170-1.
2009: Aaron Johnson; Geng Li; Timothy W Sikorski; Stephen Buratowski; Christopher L Woodcock; Danesh Moazed
Reconstitution of heterochromatin-dependent transcriptional gene silencing.
Molecular cell 2009;35(6):769-81.
2009: Manisha Sinha; Shinya Watanabe; Aaron Johnson; Danesh Moazed; Craig L Peterson
Recombinational repair within heterochromatin requires ATP-dependent chromatin remodeling.
Cell 2009;138(6):1109-21.
2009: Mario Halic; Danesh Moazed
Transposon silencing by piRNAs.
Cell 2009;138(6):1058-60.
2009: Haitao Li; Mohammad R Motamedi; Calvin K Yip; Zhanxin Wang; Thomas Walz; Dinshaw J Patel; Danesh Moazed
An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Molecular cell 2009;34(2):155-67.
2009: Brett N Tomson; Rami Rahal; Vladimír Reiser; Fernando Monje-Casas; Karim Mekhail; Danesh Moazed; Angelika Amon
Regulation of Spo12 phosphorylation and its essential role in the FEAR network.
Current biology : CB 2009;19(6):449-60.
2009: Danesh Moazed
Small RNAs in transcriptional gene silencing and genome defence.
Nature 2009;457(7228):413-20.
2008: Mohammad R Motamedi; Eun-Jin Erica Hong; Xue Li; Scott Gerber; Carilee Denison; Steven P Gygi; Danesh Moazed
HP1 proteins form distinct complexes and mediate heterochromatic gene silencing by nonoverlapping mechanisms.
Molecular cell 2008;32(6):778-90.
2008: Karim Mekhail; Jan Seebacher; Steven P Gygi; Danesh Moazed
Role for perinuclear chromosome tethering in maintenance of genome stability.
Nature 2008;456(7222):667-70.
2008: Johannes R Buchberger; Megumi Onishi; Geng Li; Jan Seebacher; Adam D Rudner; Steven P Gygi; Danesh Moazed
Sir3-nucleosome interactions in spreading of silent chromatin in Saccharomyces cerevisiae.
Molecular and cellular biology 2008;28(22):6903-18.
2008: Hiten D Madhani; Nicole J Francis; Robert E Kingston; Roger D Kornberg; Danesh Moazed; Geeta J Narlikar; Barbara Panning; Kevin Struhl
Epigenomics: a roadmap, but to where?
Science (New York, N.Y.) 2008;322(5898):43-4.
2008: Marc Bühler; Noah Spies; David P Bartel; Danesh Moazed
TRAMP-mediated RNA surveillance prevents spurious entry of RNAs into the Schizosaccharomyces pombe siRNA pathway.
Nature structural & molecular biology 2008;15(10):1015-23.
2008: Tetsushi Iida; Jun-ichi Nakayama; Danesh Moazed
siRNA-mediated heterochromatin establishment requires HP1 and is associated with antisense transcription.
Molecular cell 2008;31(2):178-89.
2008: Yariv Kanfi; Ronnie Shalman; Victoria Peshti; Shmuel N Pilosof; Yosi M Gozlan; Kevin J Pearson; Batya Lerrer; Danesh Moazed; Jean-Christophe Marine; Rafael de Cabo; Haim Y Cohen
Regulation of SIRT6 protein levels by nutrient availability.
FEBS letters 2008;582(5):543-8.
2007: Megumi Onishi; GANGUANG LIOU; Johannes R Buchberger; Thomas Walz; Danesh Moazed
Role of the conserved Sir3-BAH domain in nucleosome binding and silent chromatin assembly.
Molecular cell 2007;28(6):1015-28.
2007: Marc Bühler; Danesh Moazed
Transcription and RNAi in heterochromatic gene silencing.
Nature structural & molecular biology 2007;14(11):1041-8.
2007: Serafin U Colmenares; Shane M Buker; Marc Buhler; Mensur Dlakic; Danesh Moazed
Coupling of double-stranded RNA synthesis and siRNA generation in fission yeast RNAi.
Molecular cell 2007;27(3):449-61.
2007: Hengyao Niu; Xue Li; Emily Job; Caroline Park; Danesh Moazed; Steven P Gygi; Nancy M Hollingsworth
Mek1 kinase is regulated to suppress double-strand break repair between sister chromatids during budding yeast meiosis.
Molecular and cellular biology 2007;27(15):5456-67.
2007: georgios skiniotis; Danesh Moazed; Thomas Walz
Acetylated histone tail peptides induce structural rearrangements in the RSC chromatin remodeling complex.
The Journal of biological chemistry 2007;282(29):20804-8.
2007: Marc Bühler; Wilhelm Haas; Steven P Gygi; Danesh Moazed
RNAi-dependent and -independent RNA turnover mechanisms contribute to heterochromatic gene silencing.
Cell 2007;129(4):707-21.
2007: Fei Lan; Mikel Zaratiegui; Judit Villén; Matthew W Vaughn; André Verdel; Maite Huarte; Yujiang Shi; Steven P Gygi; Danesh Moazed; Robert A Martienssen; Yang Shi
S. pombe LSD1 homologs regulate heterochromatin propagation and euchromatic gene transcription.
Molecular cell 2007;26(1):89-101.
2007: Shane M Buker; Tetsushi Iida; Marc Bühler; Judit Villén; Steven P Gygi; Jun-Ichi Nakayama; Danesh Moazed
Two different Argonaute complexes are required for siRNA generation and heterochromatin assembly in fission yeast.
Nature structural & molecular biology 2007;14(3):200-7.
2007: Corey A Morris; Danesh Moazed
Centromere assembly and propagation.
Cell 2007;128(4):647-50.
2006: Julie Huang; Ilana L Brito; Judit Villén; Steven P Gygi; Angelika Amon; Danesh Moazed
Inhibition of homologous recombination by a cohesin-associated clamp complex recruited to the rDNA recombination enhancer.
Genes & development 2006;20(20):2887-901.
2006: Mirela Matecic; Kristen Martins-Taylor; Merrit Hickman; Jason Tanny; Danesh Moazed; Scott G Holmes
New alleles of SIR2 define cell-cycle-specific silencing functions.
Genetics 2006;173(4):1939-50.
2006: Marc Bühler; André Verdel; Danesh Moazed
Tethering RITS to a nascent transcript initiates RNAi- and heterochromatin-dependent gene silencing.
Cell 2006;125(5):873-86.
2006: Julie Huang; Danesh Moazed
Sister chromatid cohesion in silent chromatin: each sister to her own ring.
Genes & development 2006;20(2):132-7.
2006: Danesh Moazed; Marc Bühler; Shane M Buker; Serafin U Colmenares; E L Gerace; Scott A Gerber; Eun-Jin Erica Hong; Mohammad R Motamedi; André Verdel; Judit Villén; Steven P Gygi
Studies on the mechanism of RNAi-dependent heterochromatin assembly.
Cold Spring Harbor symposia on quantitative biology 2006;71():461-71.
2005: André Verdel; Danesh Moazed
RNAi-directed assembly of heterochromatin in fission yeast.
FEBS letters 2005;579(26):5872-8.
2005: Eun-Jin Erica Hong; Judit Villén; Erica L Gerace; Steven P Gygi; Danesh Moazed
A cullin E3 ubiquitin ligase complex associates with Rik1 and the Clr4 histone H3-K9 methyltransferase and is required for RNAi-mediated heterochromatin formation.
RNA biology 2005;2(3):106-11.
2005: Stephen Buratowski; Danesh Moazed
Gene regulation: expression and silencing coupled.
Nature 2005;435(7046):1174-5.
2005: Adam D Rudner; Brian E Hall; Tom Ellenberger; Danesh Moazed
A nonhistone protein-protein interaction required for assembly of the SIR complex and silent chromatin.
Molecular and cellular biology 2005;25(11):4514-28.
2005: GANGUANG LIOU; Jason Tanny; Ryan G Kruger; Thomas Walz; Danesh Moazed
Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation.
Cell 2005;121(4):515-27.
2005: Carilee Denison; Adam D Rudner; Scott A Gerber; Corey E Bakalarski; Danesh Moazed; Steven P Gygi
A proteomic strategy for gaining insights into protein sumoylation in yeast.
Molecular & cellular proteomics : MCP 2005;4(3):246-54.
2005: Tomoyasu Sugiyama; Hugh P Cam; André Verdel; Danesh Moazed; Shiv I S Grewal
RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(1):152-7.
2005: André Verdel; Danesh Moazed
Labeling and characterization of small RNAs associated with the RNA interference effector complex RITS.
Methods in enzymology 2005;392():297-307.
2004: Mohammad R Motamedi; André Verdel; Serafin U Colmenares; Scott A Gerber; Steven P Gygi; Danesh Moazed
Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs.
Cell 2004;119(6):789-802.
2004: Ken-ichi Noma; Tomoyasu Sugiyama; Hugh P Cam; André Verdel; Martin Zofall; Songtao Jia; Danesh Moazed; Shiv I S Grewal
RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing.
Nature genetics 2004;36(11):1174-80.
2004: Jason Tanny; Donald Kirkpatrick; Scott A Gerber; Steven P Gygi; Danesh Moazed
Budding yeast silencing complexes and regulation of Sir2 activity by protein-protein interactions.
Molecular and cellular biology 2004;24(16):6931-46.
2004: Frank Stegmeier; Julie Huang; Rami Rahal; Jessica Zmolik; Danesh Moazed; Angelika Amon
The replication fork block protein Fob1 functions as a negative regulator of the FEAR network.
Current biology : CB 2004;14(6):467-80.
2004: André Verdel; Songtao Jia; Scott Gerber; Tomoyasu Sugiyama; Steven P Gygi; Shiv I S Grewal; Danesh Moazed
RNAi-mediated targeting of heterochromatin by the RITS complex.
Science (New York, N.Y.) 2004;303(5658):672-6.
2004: Danesh Moazed; Adam D Rudner; Julie Huang; Georg J Hoppe; Jason Tanny
A model for step-wise assembly of heterochromatin in yeast.
Novartis Foundation symposium 2004;259():48-56; discussion 56-62, 163-9.
2003: Julie Huang; Danesh Moazed
Association of the RENT complex with nontranscribed and coding regions of rDNA and a regional requirement for the replication fork block protein Fob1 in rDNA silencing.
Genes & development 2003;17(17):2162-76.
2003: Shiv I S Grewal; Danesh Moazed
Heterochromatin and epigenetic control of gene expression.
Science (New York, N.Y.) 2003;301(5634):798-802.
2003: Gurumurthy D Shankaranarayana; Mohammad R Motamedi; Danesh Moazed; Shiv I S Grewal
Sir2 regulates histone H3 lysine 9 methylation and heterochromatin assembly in fission yeast.
Current biology : CB 2003;13(14):1240-6.
2003: Ju-Fang Chang; Brian E Hall; Jason Tanny; Danesh Moazed; David J Filman; Tom Ellenberger
Structure of the coiled-coil dimerization motif of Sir4 and its interaction with Sir3.
Structure (London, England : 1993) 2003;11(6):637-49.
2002: Jiaxu Li; Danesh Moazed; Steven P Gygi
Association of the histone methyltransferase Set2 with RNA polymerase II plays a role in transcription elongation.
The Journal of biological chemistry 2002;277(51):49383-8.
2002: Jason Tanny; Danesh Moazed
Recognition of acetylated proteins: lessons from an ancient family of enzymes.
Structure (London, England : 1993) 2002;10(10):1290-2.
2002: Georg J Hoppe; Jason Tanny; Adam D Rudner; Scott A Gerber; Sherwin Danaie; Steven P Gygi; Danesh Moazed
Steps in assembly of silent chromatin in yeast: Sir3-independent binding of a Sir2/Sir4 complex to silencers and role for Sir2-dependent deacetylation.
Molecular and cellular biology 2002;22(12):4167-80.
2002: Doug R Kellogg; Danesh Moazed
Protein- and immunoaffinity purification of multiprotein complexes.
Methods in enzymology 2002;351():172-83.
2001: Danesh Moazed
Common themes in mechanisms of gene silencing.
Molecular cell 2001;8(3):489-98.
2001: Wenying Shou; Kathleen M Sakamoto; J Keener; K W Morimoto; E E Traverso; Ramzi Azzam; Georg J Hoppe; R M Renny Feldman; JA DeModena; Danesh Moazed; Harry Charbonneau; M Nomura; Raymond J Deshaies
Net1 stimulates RNA polymerase I transcription and regulates nucleolar structure independently of controlling mitotic exit.
Molecular cell 2001;8(1):45-55.
2001: Danesh Moazed
Enzymatic activities of Sir2 and chromatin silencing.
Current opinion in cell biology 2001;13(2):232-8.
2001: Jason Tanny; Danesh Moazed
Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(2):415-20.
1999: Jason Tanny; G J Dowd; Julie Huang; H Hilz; Danesh Moazed
An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing.
Cell 1999;99(7):735-45.
1999: Aaron F Straight; Wenying Shou; G J Dowd; C W Turck; Raymond J Deshaies; A D Johnson; Danesh Moazed
Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity.
Cell 1999;97(2):245-56.
1999: Wenying Shou; J H Seol; A Shevchenko; Christopher Baskerville; Danesh Moazed; Z W Chen; J Jang; Andrej Shevchenko; Harry Charbonneau; Raymond J Deshaies
Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex.
Cell 1999;97(2):233-44.
1999: C Merryman; Danesh Moazed; G Daubresse; Harry F Noller
Nucleotides in 23S rRNA protected by the association of 30S and 50S ribosomal subunits.
Journal of molecular biology 1999;285(1):107-13.
1999: C Merryman; Danesh Moazed; J McWhirter; Harry F Noller
Nucleotides in 16S rRNA protected by the association of 30S and 50S ribosomal subunits.
Journal of molecular biology 1999;285(1):97-105.
1996: Danesh Moazed; D Johnson
A deubiquitinating enzyme interacts with SIR4 and regulates silencing in S. cerevisiae.
Cell 1996;86(4):667-77.
1995: Danesh Moazed; R R Samaha; C Gualerzi; Harry F Noller
Specific protection of 16 S rRNA by translational initiation factors.
Journal of molecular biology 1995;248(2):207-10.
1991: Danesh Moazed; Harry F Noller
Sites of interaction of the CCA end of peptidyl-tRNA with 23S rRNA.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(9):3725-8.
1990: Danesh Moazed; Harry F Noller
Binding of tRNA to the ribosomal A and P sites protects two distinct sets of nucleotides in 16 S rRNA.
Journal of molecular biology 1990;211(1):135-45.
1989: Danesh Moazed; Harry F Noller
Intermediate states in the movement of transfer RNA in the ribosome.
Nature 1989;342(6246):142-8.
1989: Danesh Moazed; Harry F Noller
Interaction of tRNA with 23S rRNA in the ribosomal A, P, and E sites.
Cell 1989;57(4):585-97.
1988: Danesh Moazed; J M Robertson; Harry F Noller
Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA.
Nature 1988;334(6180):362-4.
1987: Danesh Moazed; Harry F Noller
Chloramphenicol, erythromycin, carbomycin and vernamycin B protect overlapping sites in the peptidyl transferase region of 23S ribosomal RNA.
Biochimie 1987;69(8):879-84.
1987: Harry F Noller; S Stern; Danesh Moazed; Edmund (Ted) Powers; P Svensson; L M Changchien
Studies on the architecture and function of 16S rRNA.
Cold Spring Harbor symposia on quantitative biology 1987;52():695-708.