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Italo Mocchetti

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Italo Mocchetti; Lee A Campbell; G Jean Harry; Valeriya Avdoshina
When human immunodeficiency virus meets chemokines and microglia: neuroprotection or neurodegeneration?
Italo Mocchetti
Catechins in neuroAIDS.
Alessia Bachis; Maia Parsadanian; Luigi Zecca; Valeriya Avdoshina; Italo Mocchetti
Human immunodeficiency virus type 1 alters brain-derived neurotrophic factor processing in neurons.

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All Publications

2013: Italo Mocchetti; Lee A Campbell; G Jean Harry; Valeriya Avdoshina
When human immunodeficiency virus meets chemokines and microglia: neuroprotection or neurodegeneration?
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2013;8(1):118-31.
2012: Italo Mocchetti
Catechins in neuroAIDS.
Journal of neurovirology 2012;18(6):443-4.
2012: Alessia Bachis; Maia Parsadanian; Luigi Zecca; Valeriya Avdoshina; Italo Mocchetti
Human immunodeficiency virus type 1 alters brain-derived neurotrophic factor processing in neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(28):9477-84.
2012: Alexander Kirilyuk; Italo Mocchetti; Nagarajan Pattabiraman; Geetaram Sahu; Mika Shimoji; Jeffrey A Toretsky; Vladimir N Uversky; Christopher Albanese; Jason Catania; Antonio Giordano; Maria Laura Avantaggiati
An intrinsically disordered region of the acetyltransferase p300 with similarity to prion-like domains plays a role in aggregation.
PloS one 2012;7(11):e48243.
2011: Norton Neff; Italo Mocchetti; Alessandro Guidotti
Preface. Fifty years of Neuropharmacology a tribute to Ermino Costa.
Pharmacological research : the official journal of the Italian Pharmacological Society 2011;64(4):309.
2011: Italo Mocchetti
Pharmacological regulation of gene expression.
Pharmacological research : the official journal of the Italian Pharmacological Society 2011;64(4):323-6.
2011: Italo Mocchetti; Alessandro Guidotti
The Fidia-Georgetown Institute for the Neurosciences (FGIN) 1985-1994.
Pharmacological research : the official journal of the Italian Pharmacological Society 2011;64(4):314-5.
2011: Seung T Lim; Kamilla Esfahani; Valeriya Avdoshina; Italo Mocchetti
Exogenous gangliosides increase the release of brain-derived neurotrophic factor.
Neuropharmacology 2011;60(7-8):1160-7.
2011: Valeriya Avdoshina; Alessia Bachis; Alfredo Garzino-Demo; Chenglong Liu; Pauline M Maki; Maria C G Monaco; Rochelle E Tractenberg; Mary A Young; Italo Mocchetti
HIV-1 decreases the levels of neurotrophins in human lymphocytes.
AIDS (London, England) 2011;25(8):1126-8.
2011: Valeriya Avdoshina; Jody Becker; Lee A Campbell; Maia Parsadanian; Timothy Mhyre; Lino Tessarollo; Italo Mocchetti
Neurotrophins modulate the expression of chemokine receptors in the brain.
Journal of neurovirology 2011;17(1):58-62.
2010: Valeriya Avdoshina; Francesca Biggio; Guillermo Palchik; Lee A Campbell; Italo Mocchetti
Morphine induces the release of CCL5 from astrocytes: potential neuroprotective mechanism against the HIV protein gp120.
Glia 2010;58(13):1630-9.
2010: Alessia Bachis; Maria I Cruz; Italo Mocchetti
M-tropic HIV envelope protein gp120 exhibits a different neuropathological profile than T-tropic gp120 in rat striatum.
The European journal of neuroscience 2010;32(4):570-8.
2010: S Sakura Minami; Elkhansa Sidahmed; Saba Aid; Mika Shimoji; Takako Niikura; Italo Mocchetti; G William Rebeck; Jay S Prendergast; Chris Dealwis; Ronald Wetzel; Francesca Bosetti; Yasuji Matsuoka; Hyang-Sook Hoe; Raymond Scott Turner
Therapeutic versus neuroinflammatory effects of passive immunization is dependent on Aβ/amyloid burden in a transgenic mouse model of Alzheimer's disease.
Journal of neuroinflammation 2010;7():57.
2009: Italo Mocchetti
The areas of pathology, biomolecular mechanisms, and therapeutic approaches. Preface.
Neurotoxicity research 2009;16(3):185.
2009: Mika Shimoji; Fernando Pagan; Edward B Healton; Italo Mocchetti
CXCR4 and CXCL12 expression is increased in the nigro-striatal system of Parkinson's disease.
Neurotoxicity research 2009;16(3):318-28.
2009: Francesca Biggio; Giorgio Gorini; Cinzia Utzeri; Pierluigi Olla; Francesco Marrosu; Italo Mocchetti; Paolo Follesa
Chronic vagus nerve stimulation induces neuronal plasticity in the rat hippocampus.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2009;12(9):1209-21.
2009: Farid Ahmed; Linda MacArthur; Maria A De Bernardi; Italo Mocchetti
Retrograde and anterograde transport of HIV protein gp120 in the nervous system.
Brain, behavior, and immunity 2009;23(3):355-64.
2009: Alessia Bachis; Francesca Biggio; Eugene O Major; Italo Mocchetti
M- and T-tropic HIVs promote apoptosis in rat neurons.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2009;4(1):150-60.
2008: Alessia Bachis; Alessandra Mallei; Maria Idalia Cruz; Anton Wellstein; Italo Mocchetti
Chronic antidepressant treatments increase basic fibroblast growth factor and fibroblast growth factor-binding protein in neurons.
Neuropharmacology 2008;55(7):1114-20.
2008: Alessia Bachis; Maria Idalia Cruz; Rachel L Nosheny; Italo Mocchetti
Chronic unpredictable stress promotes neuronal apoptosis in the cerebral cortex.
Neuroscience letters 2008;442(2):104-8.
2008: Farid Ahmed; Lino Tessarollo; Carol Thiele; Italo Mocchetti
Brain-derived neurotrophic factor modulates expression of chemokine receptors in the brain.
Brain research 2008;1227():1-11.
2008: Italo Mocchetti; Milton Brown
Targeting neurotrophin receptors in the central nervous system.
CNS & neurological disorders drug targets 2008;7(1):71-82.
2008: Italo Mocchetti; Alessia Bachis; Eliezer Masliah
Chemokine receptors and neurotrophic factors: potential therapy against aids dementia?
Journal of neuroscience research 2008;86(2):243-55.
2007: Italo Mocchetti; Rachel L Nosheny; Gianluigi Tanda; Ke Ren; Edwin M Meyer
Brain-derived neurotrophic factor prevents human immunodeficiency virus type 1 protein gp120 neurotoxicity in the rat nigrostriatal system.
Annals of the New York Academy of Sciences 2007;1122():144-54.
2007: Italo Mocchetti; Alessia Bachis; Rachel L Nosheny; Gianluigi Tanda
Brain-derived neurotrophic factor expression in the substantia nigra does not change after lesions of dopaminergic neurons.
Neurotoxicity research 2007;12(2):135-43.
2007: Rachel L Nosheny; Farid Ahmed; Alexander Yakovlev; Edwin M Meyer; Ke Ren; Lino Tessarollo; Italo Mocchetti
Brain-derived neurotrophic factor prevents the nigrostriatal degeneration induced by human immunodeficiency virus-1 glycoprotein 120 in vivo.
The European journal of neuroscience 2007;25(8):2275-84.
2006: Rachel L Nosheny; Alessia Bachis; Sadia A Aden; Maria A De Bernardi; Italo Mocchetti
Intrastriatal administration of human immunodeficiency virus-1 glycoprotein 120 reduces glial cell-line derived neurotrophic factor levels and causes apoptosis in the substantia nigra.
Journal of neurobiology 2006;66(12):1311-21.
2006: Christine Seitz McCauslin; Victoria Heath; Anna Maria Colangelo; Radek Malik; Sook Lee; Alessandra Mallei; Italo Mocchetti; Peter F Johnson
CAAT/enhancer-binding protein delta and cAMP-response element-binding protein mediate inducible expression of the nerve growth factor gene in the central nervous system.
The Journal of biological chemistry 2006;281(26):17681-8.
2006: Alessia Bachis; Sadia A Aden; Rachel L Nosheny; Peter M Andrews; Italo Mocchetti
Axonal transport of human immunodeficiency virus type 1 envelope protein glycoprotein 120 is found in association with neuronal apoptosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(25):6771-80.
2006: Alessia Bachis; Italo Mocchetti
Semisynthetic sphingoglycolipid LIGA20 is neuroprotective against human immunodeficiency virus-gp120-mediated apoptosis.
Journal of neuroscience research 2006;83(5):890-6.
2005: Alessandra Mallei; Sadia A Aden; Alessia Bachis; Cinzia Brandoli; Ennio Ongini; Italo Mocchetti
The nitrosteroid NCX 1015, a prednisolone derivative, improves recovery of function in rats after spinal cord injury.
Brain research 2005;1062(1-2):16-25.
2005: Rachel L Nosheny; Italo Mocchetti; Alessia Bachis
Brain-derived neurotrophic factor as a prototype neuroprotective factor against HIV-1-associated neuronal degeneration.
Neurotoxicity research 2005;8(1-2):187-98.
2005: Italo Mocchetti
Exogenous gangliosides, neuronal plasticity and repair, and the neurotrophins.
Cellular and molecular life sciences : CMLS 2005;62(19-20):2283-94.
2005: Alessia Bachis; Italo Mocchetti
Brain-derived neurotrophic factor is neuroprotective against human immunodeficiency virus-1 envelope proteins.
Annals of the New York Academy of Sciences 2005;1053():247-57.
2004: Rachel L Nosheny; Alessia Bachis; Elio Acquas; Italo Mocchetti
Human immunodeficiency virus type 1 glycoprotein gp120 reduces the levels of brain-derived neurotrophic factor in vivo: potential implication for neuronal cell death.
The European journal of neuroscience 2004;20(11):2857-64.
2004: Alessandra Mallei; Stuart J Rabin; Italo Mocchetti
Autocrine regulation of nerve growth factor expression by Trk receptors.
Journal of neurochemistry 2004;90(5):1085-93.
2004: Anna Maria Colangelo; Alessandra Mallei; Peter F Johnson; Italo Mocchetti
Synergistic effect of dexamethasone and beta-adrenergic receptor agonists on the nerve growth factor gene transcription.
Brain research. Molecular brain research 2004;124(2):97-104.
2004: Italo Mocchetti; Alessia Bachis
Brain-derived neurotrophic factor activation of TrkB protects neurons from HIV-1/gp120-induced cell death.
Critical reviews in neurobiology 2004;16(1-2):51-7.
2004: Elio Acquas; Alessia Bachis; Rachel L Nosheny; Ibolja Cernak; Italo Mocchetti
Human immunodeficiency virus type 1 protein gp120 causes neuronal cell death in the rat brain by activating caspases.
Neurotoxicity research 2004;5(8):605-15.
2004: Alessia Bachis; Italo Mocchetti
The chemokine receptor CXCR4 and not the N-methyl-D-aspartate receptor mediates gp120 neurotoxicity in cerebellar granule cells.
Journal of neuroscience research 2004;75(1):75-82.
2003: Alessia Bachis; Eugene O Major; Italo Mocchetti
Brain-derived neurotrophic factor inhibits human immunodeficiency virus-1/gp120-mediated cerebellar granule cell death by preventing gp120 internalization.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(13):5715-22.
2002: Stuart J Rabin; Alessia Bachis; Italo Mocchetti
Gangliosides activate Trk receptors by inducing the release of neurotrophins.
The Journal of biological chemistry 2002;277(51):49466-72.
2002: Alessandra Mallei; Bitao Shi; Italo Mocchetti
Antidepressant treatments induce the expression of basic fibroblast growth factor in cortical and hippocampal neurons.
Molecular pharmacology 2002;61(5):1017-24.
2001: BR Pflug; Anna Maria Colangelo; CS Tornatore; Italo Mocchetti
TrkA induces differentiation but not apoptosis in C6-2B glioma cells.
Journal of neuroscience research 2001;64(6):636-45.
2001: Alessia Bachis; Anna Maria Colangelo; Stefano Vicini; P P Doe; Maria A De Bernardi; Gary Brooker; Italo Mocchetti
Interleukin-10 prevents glutamate-mediated cerebellar granule cell death by blocking caspase-3-like activity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(9):3104-12.
2001: Cinzia Brandoli; B Shi; BR Pflug; Peter Andrews; Jean R Wrathall; Italo Mocchetti
Dexamethasone reduces the expression of p75 neurotrophin receptor and apoptosis in contused spinal cord.
Brain research. Molecular brain research 2001;87(1):61-70.
2000: B Shi; Italo Mocchetti
Dexamethasone induces TrkA and p75NTR immunoreactivity in the cerebral cortex and hippocampus.
Experimental neurology 2000;162(2):257-67.
1999: yang teng; Italo Mocchetti; Angelo M Taveira-DaSilva; Richard A Gillis; Jean R Wrathall
Basic fibroblast growth factor increases long-term survival of spinal motor neurons and improves respiratory function after experimental spinal cord injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(16):7037-47.
1998: B Shi; Stuart J Rabin; Cinzia Brandoli; Italo Mocchetti
Dexamethasone induces hypertrophy of developing medial septum cholinergic neurons: potential role of nerve growth factor.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(22):9326-34.
1998: Ann M Marini; Stuart J Rabin; Robert Henry Lipsky; Italo Mocchetti
Activity-dependent release of brain-derived neurotrophic factor underlies the neuroprotective effect of N-methyl-D-aspartate.
The Journal of biological chemistry 1998;273(45):29394-9.
1998: Cinzia Brandoli; A Sanna; Maria A De Bernardi; P Follesa; Gary Brooker; Italo Mocchetti
Brain-derived neurotrophic factor and basic fibroblast growth factor downregulate NMDA receptor function in cerebellar granule cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(19):7953-61.
1998: Anna Maria Colangelo; Peter F Johnson; Italo Mocchetti
beta-adrenergic receptor-induced activation of nerve growth factor gene transcription in rat cerebral cortex involves CCAAT/enhancer-binding protein delta.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(18):10920-5.
1998: Stuart J Rabin; CS Tornatore; B Baker-Cairns; G Spiga; Italo Mocchetti
TrkA receptors delay C6-2B glioma cell growth in rat striatum.
Brain research. Molecular brain research 1998;56(1-2):273-6.
1998: yang teng; Italo Mocchetti; Jean R Wrathall
Basic and acidic fibroblast growth factors protect spinal motor neurones in vivo after experimental spinal cord injury.
The European journal of neuroscience 1998;10(2):798-802.
1998: P Follesa; Jean R Wrathall; Italo Mocchetti
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)-quinoxaline (NBQX) increases fibroblast growth factor mRNA levels after contusive spinal cord injury.
Brain research 1998;782(1-2):306-9.
1998: Anna Maria Colangelo; P Follesa; Italo Mocchetti
Differential induction of nerve growth factor and basic fibroblast growth factor mRNA in neonatal and aged rat brain.
Brain research. Molecular brain research 1998;53(1-2):218-25.
1997: Ann M Marini; G Spiga; Italo Mocchetti
Toward the development of strategies to prevent ischemic neuronal injury. In vitro studies.
Annals of the New York Academy of Sciences 1997;825():209-19.
1997: CS Tornatore; Stuart J Rabin; B Baker-Cairns; S Keir; Italo Mocchetti
Engraftment of C6-2B cells into the striatum of ACI nude rats as a tool for comparison of the in vitro and in vivo phenotype of a glioma cell line.
Cell transplantation 1997;6(3):317-26.
1997: C Zocchia; G Spiga; Stuart J Rabin; Maria C Grekova; John R Richert; ON Chernyshev; Carol A. Colton; Italo Mocchetti
Biological activity of interleukin-10 in the central nervous system.
Neurochemistry international 1997;30(4-5):433-9.
1996: Italo Mocchetti; Stuart J Rabin; Anna Maria Colangelo; S R Whittemore; Jean R Wrathall
Increased basic fibroblast growth factor expression following contusive spinal cord injury.
Experimental neurology 1996;141(1):154-64.
1996: M A De Bernardi; S J Rabins; Anna Maria Colangelo; Gary Brooker; Italo Mocchetti
TrkA mediates the nerve growth factor-induced intracellular calcium accumulation.
The Journal of biological chemistry 1996;271(11):6092-8.
1996: Italo Mocchetti; G Spiga; V Y Hayes; PJ Isackson; Anna Maria Colangelo
Glucocorticoids differentially increase nerve growth factor and basic fibroblast growth factor expression in the rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(6):2141-8.
1996: Anna Maria Colangelo; L Pani; Italo Mocchetti
Correlation between increased AP-1NGF binding activity and induction of nerve growth factor transcription by multiple signal transduction pathways in C6-2B glioma cells.
Brain research. Molecular brain research 1996;35(1-2):1-10.
1995: Italo Mocchetti; Jean R Wrathall
Neurotrophic factors in central nervous system trauma.
Journal of neurotrauma 1995;12(5):853-70.
1995: Stuart J Rabin; Italo Mocchetti
GM1 ganglioside activates the high-affinity nerve growth factor receptor trkA.
Journal of neurochemistry 1995;65(1):347-54.
1995: V Y Hayes; PJ Isackson; M Fabrazzo; P Follesa; Italo Mocchetti
Induction of nerve growth factor and basic fibroblast growth factor mRNA following clenbuterol: contrasting anatomical and cellular localization.
Experimental neurology 1995;132(1):33-41.
1995: Martin Dym; M C Jia; Ghenima Dirami; J M Price; Stuart J Rabin; Italo Mocchetti; Neelakanta Ravindranath
Expression of c-kit receptor and its autophosphorylation in immature rat type A spermatogonia.
Biology of reproduction 1995;52(1):8-19.
1994: Anna Maria Colangelo; D W Fink; Stuart J Rabin; Italo Mocchetti
Induction of nerve growth factor responsiveness in C6-2B glioma cells by expression of trkA proto-oncogene.
Glia 1994;12(2):117-27.
1994: P Follesa; Karen Gale; Italo Mocchetti
Regional and temporal pattern of expression of nerve growth factor and basic fibroblast growth factor mRNA in rat brain following electroconvulsive shock.
Experimental neurology 1994;127(1):37-44.
1994: P Follesa; Jean R Wrathall; Italo Mocchetti
Increased basic fibroblast growth factor mRNA following contusive spinal cord injury.
Brain research. Molecular brain research 1994;22(1-4):1-8.
1993: F Y Sun; Erminio Costa; Italo Mocchetti
Adrenal steroids mediate the increase of hippocampal nerve growth factor biosynthesis following bicuculline convulsions.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1993;8(3):219-25.
1993: P Longone; Italo Mocchetti; M A Riva; W J Wojcik
Characterization of a decrease in muscarinic m2 mRNA in cerebellar granule cells by carbachol.
The Journal of pharmacology and experimental therapeutics 1993;265(1):441-6.
1993: P Follesa; Italo Mocchetti
Regulation of basic fibroblast growth factor and nerve growth factor mRNA by beta-adrenergic receptor activation and adrenal steroids in rat central nervous system.
Molecular pharmacology 1993;43(2):132-8.
1992: X Z Ding; Italo Mocchetti
Regulation of cholecystokinin mRNA content in rat striatum: a glutamatergic hypothesis.
The Journal of pharmacology and experimental therapeutics 1992;263(1):368-73.
1992: MARCO RIVA; Karen Gale; Italo Mocchetti
Basic fibroblast growth factor mRNA increases in specific brain regions following convulsive seizures.
Brain research. Molecular brain research 1992;15(3-4):311-8.
1992: Italo Mocchetti
Theoretical basis for a pharmacology of nerve growth factor biosynthesis.
Annual review of pharmacology and toxicology 1992;32():303-28.
1992: X Z Ding; Italo Mocchetti
Dopaminergic regulation of cholecystokinin mRNA content in rat striatum.
Brain research. Molecular brain research 1992;12(1-3):77-83.
1991: Italo Mocchetti; M R Santi
Diazepam binding inhibitor peptide: cloning and gene expression.
Neuropharmacology 1991;30(12B):1365-71.
1991: MARCO RIVA; Italo Mocchetti
Developmental expression of the basic fibroblast growth factor gene in rat brain.
Brain research. Developmental brain research 1991;62(1):45-50.
1991: M E Reynolds; N Brunello; Italo Mocchetti; Jean R Wrathall
Localization of nerve growth factor receptor mRNA in contused rat spinal cord by in situ hybridization.
Brain research 1991;559(1):149-53.
1991: D J Messersmith; M Fabrazzo; Italo Mocchetti; Lawrence F Kromer
Effects of sciatic nerve transplants after fimbria-fornix lesion: examination of the role of nerve growth factor.
Brain research 1991;557(1-2):293-7.
1991: M Fabrazzo; Erminio Costa; Italo Mocchetti
Stimulation of nerve growth factor biosynthesis in developing rat brain by reserpine: steroids as potential mediators.
Molecular pharmacology 1991;39(2):144-9.
1990: N Brunello; M Reynolds; Jean R Wrathall; Italo Mocchetti
Increased nerve growth factor receptor mRNA in contused rat spinal cord.
Neuroscience letters 1990;118(2):238-40.
1990: Alexander G Yakovlev; M A De Bernardi; M Fabrazzo; Gary Brooker; Erminio Costa; Italo Mocchetti
Regulation of nerve growth factor receptor mRNA content by dexamethasone: in vitro and in vivo studies.
Neuroscience letters 1990;116(1-2):216-20.
1990: Italo Mocchetti
Molecular biology of diazepam binding inhibitor peptide.
Neurochemical research 1990;15(2):125-30.
1989: Italo Mocchetti; M A De Bernardi; A M Szekely; Hannu Alho; Gary Brooker; Erminio Costa
Regulation of nerve growth factor biosynthesis by beta-adrenergic receptor activation in astrocytoma cells: a potential role of c-Fos protein.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(10):3891-5.
1989: Italo Mocchetti; A Ritter; Erminio Costa
Down-regulation of proopiomelanocortin synthesis and beta-endorphin utilization in hypothalamus of morphine-tolerant rats.
Journal of molecular neuroscience : MN 1989;1(1):33-8.
1988: M A DeBernardi; R R Crowe; Italo Mocchetti; T B Shows; R L Eddy; Erminio Costa
Chromosomal localization of the human diazepam binding inhibitor gene.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(17):6561-5.
1988: R Dal Toso; M A De Bernardi; Gary Brooker; Erminio Costa; Italo Mocchetti
Beta adrenergic and prostaglandin receptor activation increases nerve growth factor mRNA content in C6-2B rat astrocytoma cells.
The Journal of pharmacology and experimental therapeutics 1988;246(3):1190-3.
1987: R Dal Toso; M A De Bernardi; Erminio Costa; Italo Mocchetti
Beta-adrenergic receptor regulation of NGF-mRNA content in rat C6-2B glioma cells.
Neuropharmacology 1987;26(12):1783-6.
1987: Italo Mocchetti; Erminio Costa
In vivo studies of the regulation of neuropeptide stores in structures of the rat brain.
Neuropharmacology 1987;26(7B):855-62.