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Daria Mochly-Rosen

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Palaniyandi Suresh Selvaraj; Sun Lihan; Ferreira Julio Cesar Batista; Mochly-Rosen Daria
Protein kinase C in heart failure: a therapeutic target?
Kaneda Hideaki; Ikeno Fumiaki; Inagaki Koichi; Mochly-Rosen Daria
Preserved coronary endothelial function by inhibition of delta protein kinase C in a porcine acute myocardial infarction model.
Churchill Eric N; Disatnik Marie-Hélène; Mochly-Rosen Daria
Time-dependent and ethanol-induced cardiac protection from ischemia mediated by mitochondrial translocation of varepsilonPKC and activation of aldehyde dehydrogenase 2.

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All Publications

2009: Palaniyandi Suresh Selvaraj; Sun Lihan; Ferreira Julio Cesar Batista; Mochly-Rosen Daria
Protein kinase C in heart failure: a therapeutic target?
Cardiovascular research 2009;82(2):229-39.
2009: Kaneda Hideaki; Ikeno Fumiaki; Inagaki Koichi; Mochly-Rosen Daria
Preserved coronary endothelial function by inhibition of delta protein kinase C in a porcine acute myocardial infarction model.
International journal of cardiology 2009;133(2):256-9.
2009: Churchill Eric N; Disatnik Marie-Hélène; Mochly-Rosen Daria
Time-dependent and ethanol-induced cardiac protection from ischemia mediated by mitochondrial translocation of varepsilonPKC and activation of aldehyde dehydrogenase 2.
Journal of molecular and cellular cardiology 2009;46(2):278-84.
2009: Castañeda Dora; Zhao Heng; Mochly-Rosen Daria; Steinberg Gary K
Activating deltaPKC antagonizes the protective effect of ERK1/2 inhibition against stroke in rats.
Brain research 2009;1251():256-61.
2009: Churchill Eric N; Qvit Nir; Mochly-Rosen Daria
Rationally designed peptide regulators of protein kinase C.
Trends in endocrinology and metabolism: TEM 2009;20(1):25-33.
2008: Churchill Eric N; Disatnik Marie-Helene; Budas Grant R; Mochly-Rosen Daria
Ethanol for cardiac ischemia: the role of protein kinase c.
Therapeutic advances in cardiovascular disease 2008;2(6):469-83.
2008: Palaniyandi Suresh Selvaraj; Inagaki Koichi; Mochly-Rosen Daria
Mast cells and epsilonPKC: a role in cardiac remodeling in hypertension-induced heart failure.
Journal of molecular and cellular cardiology 2008;45(6):779-86.
2008: Chen Che-Hong; Budas Grant R; Churchill Eric N; Disatnik Marie-Hélène; Hurley Thomas D; Mochly-Rosen Daria
Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart.
Science (New York, N.Y.) 2008;321(5895):1493-5.
2008: Kim Jeewon; Choi Yoon-La; Vallentin Alice; Hunrichs Ben S; Hellerstein Marc K; Peehl Donna M; Mochly-Rosen Daria
Centrosomal PKCbetaII and pericentrin are critical for human prostate cancer growth and angiogenesis.
Cancer research 2008;68(16):6831-9.
2008: Bright Rachel; Sun Guo-Hua; Yenari Midori A; Steinberg Gary K; Mochly-Rosen Daria
epsilonPKC confers acute tolerance to cerebral ischemic reperfusion injury.
Neuroscience letters 2008;441(1):120-4.
2008: Koyanagi Tomoyoshi; Wong Lily Y; Inagaki Koichi; Petrauskene Olga V; Mochly-Rosen Daria
Alteration of gene expression during progression of hypertension-induced cardiac dysfunction in rats.
American journal of physiology. Heart and circulatory physiology 2008;295(1):H220-6.
2008: Inagaki Koichi; Koyanagi Tomoyoshi; Berry Natalia C; Sun Lihan; Mochly-Rosen Daria
Pharmacological inhibition of epsilon-protein kinase C attenuates cardiac fibrosis and dysfunction in hypertension-induced heart failure.
Hypertension 2008;51(6):1565-9.
2008: Yao Lina; Fan Peidong; Jiang Zhan; Gordon Adrienne; Mochly-Rosen Daria; Diamond Ivan
Dopamine and ethanol cause translocation of epsilonPKC associated with epsilonRACK: cross-talk between cAMP-dependent protein kinase A and protein kinase C signaling pathways.
Molecular pharmacology 2008;73(4):1105-12.
2008: Kvezereli M; Vallentin A; Mochly-Rosen D; Busque S; Fontaine M J
Islet cell survival during isolation improved through protein kinase C epsilon activation.
Transplantation proceedings 2008;40(2):375-8.
2008: Qi Xin; Mochly-Rosen Daria
The PKCdelta -Abl complex communicates ER stress to the mitochondria - an essential step in subsequent apoptosis.
Journal of cell science 2008;121(Pt 6):804-13.
2008: Bates Eric; Bode Christoph; Costa Marco; Gibson C Michael; Granger Christopher; Green Cindy; Grimes Kevin; Harrington Robert; Huber Kurt; Kleiman Neal; Mochly-Rosen Daria; Roe Matthew; Sadowski Zygmunt; Solomon Scott; Widimsky Petr
Intracoronary KAI-9803 as an adjunct to primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction.
Circulation 2008;117(7):886-96.
2008: Qi Xin; Inagaki Koichi; Sobel Raymond A; Mochly-Rosen Daria
Sustained pharmacological inhibition of deltaPKC protects against hypertensive encephalopathy through prevention of blood-brain barrier breakdown in rats.
The Journal of clinical investigation 2008;118(1):173-82.
2008: Churchill Eric; Budas Grant; Vallentin Alice; Koyanagi Tomoyoshi; Mochly-Rosen Daria
PKC isozymes in chronic cardiac disease: possible therapeutic targets?
Annual review of pharmacology and toxicology 2008;48():569-99.
2007: Newton Alexandra C; Mochly-Rosen Daria
Induced fit and wit: celebrating the life of Daniel E. Koshland, Jr. (1920 - 2007).
IUBMB life 2007;59(12):741-3.
2007: Budas G R; Mochly-Rosen D
Mitochondrial protein kinase Cepsilon (PKCepsilon): emerging role in cardiac protection from ischaemic damage.
Biochemical Society transactions 2007;35(Pt 5):1052-4.
2007: Churchill E N; Mochly-Rosen D
The roles of PKCdelta and epsilon isoenzymes in the regulation of myocardial ischaemia/reperfusion injury.
Biochemical Society transactions 2007;35(Pt 5):1040-2.
2007: Budas G R; Koyanagi T; Churchill E N; Mochly-Rosen D
Competitive inhibitors and allosteric activators of protein kinase C isoenzymes: a personal account and progress report on transferring academic discoveries to the clinic.
Biochemical Society transactions 2007;35(Pt 5):1021-6.
2007: Qi Xin; Vallentin Alice; Churchill Eric; Mochly-Rosen Daria
deltaPKC participates in the endoplasmic reticulum stress-induced response in cultured cardiac myocytes and ischemic heart.
Journal of molecular and cellular cardiology 2007;43(4):420-8.
2007: Koyanagi Tomoyoshi; Noguchi Kenichiro; Ootani Akifumi; Inagaki Koichi; Robbins Robert C; Mochly-Rosen Daria
Pharmacological inhibition of epsilon PKC suppresses chronic inflammation in murine cardiac transplantation model.
Journal of molecular and cellular cardiology 2007;43(4):517-22.
2007: Shimohata Takayoshi; Zhao Heng; Sung Jae Hoon; Sun Guohua; Mochly-Rosen Daria; Steinberg Gary K
Suppression of deltaPKC activation after focal cerebral ischemia contributes to the protective effect of hypothermia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(8):1463-75.
2007: Battaini Fiorenzo; Mochly-Rosen Daria
Happy birthday protein kinase C: past, present and future of a superfamily.
Pharmacological research : the official journal of the Italian Pharmacological Society 2007;55(6):461-6.
2007: Kheifets Viktoria; Mochly-Rosen Daria
Insight into intra- and inter-molecular interactions of PKC: design of specific modulators of kinase function.
Pharmacological research : the official journal of the Italian Pharmacological Society 2007;55(6):467-76.
2007: Budas Grant R; Churchill Eric N; Mochly-Rosen Daria
Cardioprotective mechanisms of PKC isozyme-selective activators and inhibitors in the treatment of ischemia-reperfusion injury.
Pharmacological research : the official journal of the Italian Pharmacological Society 2007;55(6):523-36.
2007: Bright Rachel; Steinberg Gary K; Mochly-Rosen Daria
DeltaPKC mediates microcerebrovascular dysfunction in acute ischemia and in chronic hypertensive stress in vivo.
Brain research 2007;1144():146-55.
2007: Liron Tamar; Chen Leon E; Khaner Hanita; Vallentin Alice; Mochly-Rosen Daria
Rational design of a selective antagonist of epsilon protein kinase C derived from the selective allosteric agonist, pseudo-RACK peptide.
Journal of molecular and cellular cardiology 2007;42(4):835-41.
2007: Ikeno Fumiaki; Inagaki Koichi; Rezaee Mehrdad; Mochly-Rosen Daria
Impaired perfusion after myocardial infarction is due to reperfusion-induced deltaPKC-mediated myocardial damage.
Cardiovascular research 2007;73(4):699-709.
2007: Brandman Relly; Disatnik Marie-Hélène; Churchill Eric; Mochly-Rosen Daria
Peptides derived from the C2 domain of protein kinase C epsilon (epsilon PKC) modulate epsilon PKC activity and identify potential protein-protein interaction surfaces.
The Journal of biological chemistry 2007;282(6):4113-23.
2007: Vallentin Alice; Mochly-Rosen Daria
RBCK1, a protein kinase CbetaI (PKCbetaI)-interacting protein, regulates PKCbeta-dependent function.
The Journal of biological chemistry 2007;282(3):1650-7.
2007: Mamidipudi Vidya; Miller Laura D; Mochly-Rosen Daria; Cartwright Christine A
Peptide modulators of Src activity in G1 regulate entry into S phase and proliferation of NIH 3T3 cells.
Biochemical and biophysical research communications 2007;352(2):423-30.
2007: Siwko Stefan; Mochly-Rosen Daria
Use of a novel method to find substrates of protein kinase C delta identifies M2 pyruvate kinase.
The international journal of biochemistry & cell biology 2007;39(5):978-87.
2006: Kheifets Viktoria; Bright Rachel; Inagaki Koichi; Schechtman Deborah; Mochly-Rosen Daria
Protein kinase C delta (deltaPKC)-annexin V interaction: a required step in deltaPKC translocation and function.
The Journal of biological chemistry 2006;281(32):23218-26.
2006: Inagaki Koichi; Churchill Eric; Mochly-Rosen Daria
Epsilon protein kinase C as a potential therapeutic target for the ischemic heart.
Cardiovascular research 2006;70(2):222-30.
2005: Bright Rachel; Mochly-Rosen Daria
The role of protein kinase C in cerebral ischemic and reperfusion injury.
Stroke; a journal of cerebral circulation 2005;36(12):2781-90.
2005: Malhotra Ashwani; Begley Rebecca; Kang Barinder P S; Rana Irmindra; Liu Jing; Yang Guiping; Mochly-Rosen Daria; Meggs Leonard G
PKC-{epsilon}-dependent survival signals in diabetic hearts.
American journal of physiology. Heart and circulatory physiology 2005;289(4):H1343-50.
2005: Szabo Gyongyi; Hoek Jan B; Darley-Usmar Victor; Hajnoczky Gyorgy; Knudsen Thomas; Mochly-Rosen Daria; Zakhari Sam
RSA 2004: combined basic research satellite symposium - session three: alcohol and mitochondrial metabolism: at the crossroads of life and death.
Alcoholism, clinical and experimental research 2005;29(9):1749-52.
2005: Shumilla Jennifer A; Liron Tamar; Mochly-Rosen Daria; Kendig Joan J; Sweitzer Sarah M
Ethanol withdrawal-associated allodynia and hyperalgesia: age-dependent regulation by protein kinase C epsilon and gamma isoenzymes.
The journal of pain : official journal of the American Pain Society 2005;6(8):535-49.
2005: Inagaki K; Mochly-Rosen D
DeltaPKC-mediated activation of epsilonPKC in ethanol-induced cardiac protection from ischemia.
Journal of molecular and cellular cardiology 2005;39(2):203-11.
2005: Churchill Eric N; Murriel Christopher L; Chen Che-Hong; Mochly-Rosen Daria; Szweda Luke I
Reperfusion-induced translocation of deltaPKC to cardiac mitochondria prevents pyruvate dehydrogenase reactivation.
Circulation research 2005;97(1):78-85.
2005: Raval Ami P; Dave Kunjan R; Prado Ricardo; Katz Laurence M; Busto Raul; Sick Thomas J; Ginsberg Myron D; Mochly-Rosen Daria; Pérez-Pinzón Miguel A
Protein kinase C delta cleavage initiates an aberrant signal transduction pathway after cardiac arrest and oxygen glucose deprivation.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(6):730-41.
2005: Tanaka Masashi; Gunawan Feny; Terry Raya D; Inagaki Koichi; Caffarelli Anthony D; Hoyt Grant; Tsao Philip S; Mochly-Rosen Daria; Robbins Robert C
Inhibition of heart transplant injury and graft coronary artery disease after prolonged organ ischemia by selective protein kinase C regulators.
The Journal of thoracic and cardiovascular surgery 2005;129(5):1160-7.
2005: Li Hui-Fang; Mochly-Rosen Daria; Kendig Joan J
Protein kinase Cgamma mediates ethanol withdrawal hyper-responsiveness of NMDA receptor currents in spinal cord motor neurons.
British journal of pharmacology 2005;144(3):301-7.
2005: Inagaki Koichi; Begley Rebecca; Ikeno Fumiaki; Mochly-Rosen Daria
Cardioprotection by epsilon-protein kinase C activation from ischemia: continuous delivery and antiarrhythmic effect of an epsilon-protein kinase C-activating peptide.
Circulation 2005;111(1):44-50.
2004: Murriel Christopher L; Churchill Eric; Inagaki Koichi; Szweda Luke I; Mochly-Rosen Daria
Protein kinase Cdelta activation induces apoptosis in response to cardiac ischemia and reperfusion damage: a mechanism involving BAD and the mitochondria.
The Journal of biological chemistry 2004;279(46):47985-91.
2004: Tanaka Masashi; Terry Raya D; Mokhtari Golnaz K; Inagaki Koichi; Koyanagi Tomoyoshi; Kofidis Theo; Mochly-Rosen Daria; Robbins Robert C
Suppression of graft coronary artery disease by a brief treatment with a selective epsilonPKC activator and a deltaPKC inhibitor in murine cardiac allografts.
Circulation 2004;110(11 Suppl 1):II194-9.
2004: Bright Rachel; Raval Ami P; Dembner Jeffrey M; Pérez-Pinzón Miguel A; Steinberg Gary K; Yenari Midori A; Mochly-Rosen Daria
Protein kinase C delta mediates cerebral reperfusion injury in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(31):6880-8.
2004: Sweitzer Sarah M; Wong Shirley M E; Tjolsen Arne; Allen Caroline P; Mochly-Rosen Daria; Kendig Joan J
Exaggerated nociceptive responses on morphine withdrawal: roles of protein kinase C epsilon and gamma.
Pain 2004;110(1-2):281-9.
2004: Miller Laura D; Lee Kelly C; Mochly-Rosen Daria; Cartwright Christine A
RACK1 regulates Src-mediated Sam68 and p190RhoGAP signaling.
Oncogene 2004;23(33):5682-6.
2004: Wang Jian; Bright Rachel; Mochly-Rosen Daria; Giffard Rona G
Cell-specific role for epsilon- and betaI-protein kinase C isozymes in protecting cortical neurons and astrocytes from ischemia-like injury.
Neuropharmacology 2004;47(1):136-45.
2004: Lange-Asschenfeldt Christian; Raval Ami P; Dave Kunjan R; Mochly-Rosen Daria; Sick Thomas J; Pérez-Pinzón Miguel A
Epsilon protein kinase C mediated ischemic tolerance requires activation of the extracellular regulated kinase pathway in the organotypic hippocampal slice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2004;24(6):636-45.
2004: Begley Rebecca; Liron Tamar; Baryza Jeremy; Mochly-Rosen Daria
Biodistribution of intracellularly acting peptides conjugated reversibly to Tat.
Biochemical and biophysical research communications 2004;318(4):949-54.
2004: Sweitzer Sarah M; Wong Shirley M E; Peters Michael C; Mochly-Rosen Daria; Yeomans David C; Kendig Joan J
Protein kinase C epsilon and gamma: involvement in formalin-induced nociception in neonatal rats.
The Journal of pharmacology and experimental therapeutics 2004;309(2):616-25.
2004: Souroujon Miriam C; Yao Lina; Chen Haibin; Endemann Gerda; Khaner Hanita; Geeraert Virginie; Schechtman Deborah; Gordon Adrienne S; Diamond Ivan; Mochly-Rosen Daria
State-specific monoclonal antibodies identify an intermediate state in epsilon protein kinase C activation.
The Journal of biological chemistry 2004;279(17):17617-24.
2004: Schechtman Deborah; Craske Madeleine L; Kheifets Viktoria; Meyer Tobias; Schechtman Jack; Mochly-Rosen Daria
A critical intramolecular interaction for protein kinase Cepsilon translocation.
The Journal of biological chemistry 2004;279(16):15831-40.
2004: Gray Mary O; Zhou Hui-Zhong; Schafhalter-Zoppoth Ingeborg; Zhu Peili; Mochly-Rosen Daria; Messing Robert O
Preservation of base-line hemodynamic function and loss of inducible cardioprotection in adult mice lacking protein kinase C epsilon.
The Journal of biological chemistry 2004;279(5):3596-604.
2003: Murriel Christopher L; Mochly-Rosen Daria
Opposing roles of delta and epsilonPKC in cardiac ischemia and reperfusion: targeting the apoptotic machinery.
Archives of biochemistry and biophysics 2003;420(2):246-54.
2003: Inagaki Koichi; Chen Leon; Ikeno Fumiaki; Lee Felix H; Imahashi Ken-ichi; Bouley Donna M; Rezaee Mehrdad; Yock Paul G; Murphy Elizabeth; Mochly-Rosen Daria
Inhibition of delta-protein kinase C protects against reperfusion injury of the ischemic heart in vivo.
Circulation 2003;108(19):2304-7.
2003: Braun Martin Ulrich; Mochly-Rosen Daria
Opposing effects of delta- and zeta-protein kinase C isozymes on cardiac fibroblast proliferation: use of isozyme-selective inhibitors.
Journal of molecular and cellular cardiology 2003;35(8):895-903.
2003: Inagaki Koichi; Hahn Harvey S; Dorn Gerald W; Mochly-Rosen Daria
Additive protection of the ischemic heart ex vivo by combined treatment with delta-protein kinase C inhibitor and epsilon-protein kinase C activator.
Circulation 2003;108(7):869-75.
2003: Koponen Susanna; Kurkinen Kaisa; Akerman Karl E O; Mochly-Rosen Daria; Chan Pak H; Koistinaho Jari
Prevention of NMDA-induced death of cortical neurons by inhibition of protein kinase Czeta.
Journal of neurochemistry 2003;86(2):442-50.
2003: Xiao Guang-Qian; Mochly-Rosen Daria; Boutjdir Mohamed
PKC isozyme selective regulation of cloned human cardiac delayed slow rectifier K current.
Biochemical and biophysical research communications 2003;306(4):1019-25.
2003: Endemann Gerda; Schechtman Deborah; Mochly-Rosen Daria
Cytotoxicity of pEGFP vector is due to residues encoded by multiple cloning site.
Analytical biochemistry 2003;313(2):345-7.
2003: Raval Ami P; Dave Kunjan R; Mochly-Rosen Daria; Sick Thomas J; Pérez-Pinzón Miguel A
Epsilon PKC is required for the induction of tolerance by ischemic and NMDA-mediated preconditioning in the organotypic hippocampal slice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(2):384-91.
2003: Schechtman Deborah; Murriel Christopher; Bright Rachel; Mochly-Rosen Daria
Overlay method for detecting protein-protein interactions.
Methods in molecular biology (Clifton, N.J.) 2003;233():351-7.
2003: Schechtman Deborah; Mochly-Rosen Daria; Ron Dorit
Glutathione S-transferase pull-down assay.
Methods in molecular biology (Clifton, N.J.) 2003;233():345-50.
2003: Endemann Gerda; Mochly-Rosen Daria
Methods for detecting binding proteins: an introduction.
Methods in molecular biology (Clifton, N.J.) 2003;233():307-25.
2002: Dell Edward J; Connor Jennifer; Chen Songhai; Stebbins Elizabeth G; Skiba Nikolai P; Mochly-Rosen Daria; Hamm Heidi E
The betagamma subunit of heterotrimeric G proteins interacts with RACK1 and two other WD repeat proteins.
The Journal of biological chemistry 2002;277(51):49888-95.
2002: Inagaki Koichi; Iwanaga Yoshitaka; Sarai Nobuaki; Onozawa Yoko; Takenaka Hiroyuki; Mochly-Rosen Daria; Kihara Yasuki
Tissue angiotensin II during progression or ventricular hypertrophy to heart failure in hypertensive rats; differential effects on PKC epsilon and PKC beta.
Journal of molecular and cellular cardiology 2002;34(10):1377-85.
2002: Jin Zhu-Qiu; Zhou Hui-Zhong; Zhu Peili; Honbo Norman; Mochly-Rosen Daria; Messing Robert O; Goetzl Edward J; Karliner Joel S; Gray Mary O
Cardioprotection mediated by sphingosine-1-phosphate and ganglioside GM-1 in wild-type and PKC epsilon knockout mouse hearts.
American journal of physiology. Heart and circulatory physiology 2002;282(6):H1970-7.
2002: Knauf Jeffrey A; Ward Laura S; Nikiforov Yuri E; Nikiforova Marina; Puxeddu Efisio; Medvedovic Mario; Liron Tamar; Mochly-Rosen Daria; Fagin James A
Isozyme-specific abnormalities of PKC in thyroid cancer: evidence for post-transcriptional changes in PKC epsilon.
The Journal of clinical endocrinology and metabolism 2002;87(5):2150-9.
2002: Disatnik Marie-Hélène; Boutet Stéphane C; Lee Christine H; Mochly-Rosen Daria; Rando Thomas A
Sequential activation of individual PKC isozymes in integrin-mediated muscle cell spreading: a role for MARCKS in an integrin signaling pathway.
Journal of cell science 2002;115(Pt 10):2151-63.
2002: Ridge Karen M; Dada Laura; Lecuona Emilia; Bertorello Alejandro M; Katz Adrian I; Mochly-Rosen Daria; Sznajder Jacob I
Dopamine-induced exocytosis of Na,K-ATPase is dependent on activation of protein kinase C-epsilon and -delta.
Molecular biology of the cell 2002;13(4):1381-9.
2002: Banci Lucia; Cavallaro Gabriele; Kheifets Viktoria; Mochly-Rosen Daria
Molecular dynamics characterization of the C2 domain of protein kinase Cbeta.
The Journal of biological chemistry 2002;277(15):12988-97.
2002: Dorn Gerald W; Mochly-Rosen Daria
Intracellular transport mechanisms of signal transducers.
Annual review of physiology 2002;64():407-29.
2002: Schechtman Deborah; Mochly-Rosen Daria
Isozyme-specific inhibitors and activators of protein kinase C.
Methods in enzymology 2002;345():470-89.
2001: Chen L; Wright L R; Chen C H; Oliver S F; Wender P A; Mochly-Rosen D
Molecular transporters for peptides: delivery of a cardioprotective epsilonPKC agonist peptide into cells and intact ischemic heart using a transport system, R(7).
Chemistry & biology 2001;8(12):1123-9.
2001: Xiao G Q; Qu Y; Sun Z Q; Mochly-Rosen D; Boutjdir M
Evidence for functional role of epsilonPKC isozyme in the regulation of cardiac Na(+) channels.
American journal of physiology. Cell physiology 2001;281(5):C1477-86.
2001: Schechtman D; Mochly-Rosen D
Adaptor proteins in protein kinase C-mediated signal transduction.
Oncogene 2001;20(44):6339-47.
2001: Chen L; Hahn H; Wu G; Chen C H; Liron T; Schechtman D; Cavallaro G; Banci L; Guo Y; Bolli R; Dorn G W; Mochly-Rosen D
Opposing cardioprotective actions and parallel hypertrophic effects of delta PKC and epsilon PKC.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11114-9.
2001: Stebbins E G; Mochly-Rosen D
Binding specificity for RACK1 resides in the V5 region of beta II protein kinase C.
The Journal of biological chemistry 2001;276(32):29644-50.
2001: Mackay K; Mochly-Rosen D
Localization, anchoring, and functions of protein kinase C isozymes in the heart.
Journal of molecular and cellular cardiology 2001;33(7):1301-7.
2001: Mackay K; Mochly-Rosen D
Arachidonic acid protects neonatal rat cardiac myocytes from ischaemic injury through epsilon protein kinase C.
Cardiovascular research 2001;50(1):65-74.
2001: Chen C; Mochly-Rosen D
Opposing effects of delta and xi PKC in ethanol-induced cardioprotection.
Journal of molecular and cellular cardiology 2001;33(3):581-5.
2001: Mochly-Rosen D; Fagin J A; Knauf J A; Nikiforov Y; Liron T; Schechtman D
Spontaneous occurrence of an inhibitor of protein kinase C localization in a thyroid cancer cell line: role in thyroid tumorigenesis.
Advances in enzyme regulation 2001;41():87-97.
2000: Hu K; Mochly-Rosen D; Boutjdir M
Evidence for functional role of epsilonPKC isozyme in the regulation of cardiac Ca(2+) channels.
American journal of physiology. Heart and circulatory physiology 2000;279(6):H2658-64.
2000: Mackay K; Mochly-Rosen D
Involvement of a p38 mitogen-activated protein kinase phosphatase in protecting neonatal rat cardiac myocytes from ischemia.
Journal of molecular and cellular cardiology 2000;32(8):1585-8.
2000: Mochly-Rosen D; Wu G; Hahn H; Osinska H; Liron T; Lorenz J N; Yatani A; Robbins J; Dorn G W
Cardiotrophic effects of protein kinase C epsilon: analysis by in vivo modulation of PKCepsilon translocation.
Circulation research 2000;86(11):1173-9.
2000: Aley K O; Messing R O; Mochly-Rosen D; Levine J D
Chronic hypersensitivity for inflammatory nociceptor sensitization mediated by the epsilon isozyme of protein kinase C.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(12):4680-5.
1999: Dorn G W; Souroujon M C; Liron T; Chen C H; Gray M O; Zhou H Z; Csukai M; Wu G; Lorenz J N; Mochly-Rosen D
Sustained in vivo cardiac protection by a rationally designed peptide that causes epsilon protein kinase C translocation.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12798-803.
1999: Chen C H; Gray M O; Mochly-Rosen D
Cardioprotection from ischemia by a brief exposure to physiological levels of ethanol: role of epsilon protein kinase C.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12784-9.
1999: Rodriguez M M; Ron D; Touhara K; Chen C H; Mochly-Rosen D
RACK1, a protein kinase C anchoring protein, coordinates the binding of activated protein kinase C and select pleckstrin homology domains in vitro.
Biochemistry 1999;38(42):13787-94.
1999: Knauf J A; Elisei R; Mochly-Rosen D; Liron T; Chen X N; Gonsky R; Korenberg J R; Fagin J A
Involvement of protein kinase Cepsilon (PKCepsilon) in thyroid cell death. A truncated chimeric PKCepsilon cloned from a thyroid cancer cell line protects thyroid cells from apoptosis.
The Journal of biological chemistry 1999;274(33):23414-25.
1999: Rodriguez M M; Chen C H; Smith B L; Mochly-Rosen D
Characterization of the binding and phosphorylation of cardiac calsequestrin by epsilon protein kinase C.
FEBS letters 1999;454(3):240-6.
1999: Csukai M; Mochly-Rosen D
Pharmacologic modulation of protein kinase C isozymes: the role of RACKs and subcellular localisation.
Pharmacological research : the official journal of the Italian Pharmacological Society 1999;39(4):253-9.
1999: Mackay K; Mochly-Rosen D
An inhibitor of p38 mitogen-activated protein kinase protects neonatal cardiac myocytes from ischemia.
The Journal of biological chemistry 1999;274(10):6272-9.
1998: Laudanna C; Mochly-Rosen D; Liron T; Constantin G; Butcher E C
Evidence of zeta protein kinase C involvement in polymorphonuclear neutrophil integrin-dependent adhesion and chemotaxis.
The Journal of biological chemistry 1998;273(46):30306-15.
1998: Souroujon M C; Mochly-Rosen D
Peptide modulators of protein-protein interactions in intracellular signaling.
Nature biotechnology 1998;16(10):919-24.
1998: Mochly-Rosen D; Gordon A S
Anchoring proteins for protein kinase C: a means for isozyme selectivity.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(1):35-42.
1998: Csukai M; Mochly-Rosen D
Molecular genetic approaches. II. Expression-interaction cloning.
Methods in molecular biology (Clifton, N.J.) 1998;88():133-9.
1997: Gray M O; Karliner J S; Mochly-Rosen D
A selective epsilon-protein kinase C antagonist inhibits protection of cardiac myocytes from hypoxia-induced cell death.
The Journal of biological chemistry 1997;272(49):30945-51.
1997: Csukai M; Chen C H; De Matteis M A; Mochly-Rosen D
The coatomer protein beta'-COP, a selective binding protein (RACK) for protein kinase Cepsilon.
The Journal of biological chemistry 1997;272(46):29200-6.
1997: Yedovitzky M; Mochly-Rosen D; Johnson J A; Gray M O; Ron D; Abramovitch E; Cerasi E; Nesher R
Translocation inhibitors define specificity of protein kinase C isoenzymes in pancreatic beta-cells.
The Journal of biological chemistry 1997;272(3):1417-20.
1996: Johnson J A; Gray M O; Karliner J S; Chen C H; Mochly-Rosen D
An improved permeabilization protocol for the introduction of peptides into cardiac myocytes. Application to protein kinase C research.
Circulation research 1996;79(6):1086-99.
1996: Johnson J A; Gray M O; Chen C H; Mochly-Rosen D
A protein kinase C translocation inhibitor as an isozyme-selective antagonist of cardiac function.
The Journal of biological chemistry 1996;271(40):24962-6.
1996: Smith B L; Krushelnycky B W; Mochly-Rosen D; Berg P
The HIV nef protein associates with protein kinase C theta.
The Journal of biological chemistry 1996;271(28):16753-7.
1995: Disatnik M H; Jones S N; Mochly-Rosen D
Stimulus-dependent subcellular localization of activated protein kinase C; a study with acidic fibroblast growth factor and transforming growth factor-beta 1 in cardiac myocytes.
Journal of molecular and cellular cardiology 1995;27(11):2473-81.
1995: Ron D; Luo J; Mochly-Rosen D
C2 region-derived peptides inhibit translocation and function of beta protein kinase C in vivo.
The Journal of biological chemistry 1995;270(41):24180-7.
1995: Mochly-Rosen D; Smith B L; Chen C H; Disatnik M H; Ron D
Interaction of protein kinase C with RACK1, a receptor for activated C-kinase: a role in beta protein kinase C mediated signal transduction.
Biochemical Society transactions 1995;23(3):596-600.
1995: Brzoska P M; Chen H; Zhu Y; Levin N A; Disatnik M H; Mochly-Rosen D; Murnane J P; Christman M F
The product of the ataxia-telangiectasia group D complementing gene, ATDC, interacts with a protein kinase C substrate and inhibitor.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):7824-8.
1995: Johnson J A; Mochly-Rosen D
Inhibition of the spontaneous rate of contraction of neonatal cardiac myocytes by protein kinase C isozymes. A putative role for the epsilon isozyme.
Circulation research 1995;76(4):654-63.
1995: Ron D; Mochly-Rosen D
An autoregulatory region in protein kinase C: the pseudoanchoring site.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(2):492-6.
1994: Ron D; Mochly-Rosen D
Agonists and antagonists of protein kinase C function, derived from its binding proteins.
The Journal of biological chemistry 1994;269(34):21395-8.
1994: Disatnik M H; Winnier A R; Mochly-Rosen D; Arteaga C L
Distinct responses of protein kinase C isozymes to c-erbB-2 activation in SKBR-3 human breast carcinoma cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(8):873-80.
1994: Ron D; Chen C H; Caldwell J; Jamieson L; Orr E; Mochly-Rosen D
Cloning of an intracellular receptor for protein kinase C: a homolog of the beta subunit of G proteins.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(3):839-43.
1994: Disatnik M H; Buraggi G; Mochly-Rosen D
Localization of protein kinase C isozymes in cardiac myocytes.
Experimental cell research 1994;210(2):287-97.
1994: Disatnik M H; Hernandez-Sotomayor S M; Jones G; Carpenter G; Mochly-Rosen D
Phospholipase C-gamma 1 binding to intracellular receptors for activated protein kinase C.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(2):559-63.
1992: Smith B L; Mochly-Rosen D
Inhibition of protein kinase C function by injection of intracellular receptors for the enzyme.
Biochemical and biophysical research communications 1992;188(3):1235-40.
1992: Mochly-Rosen D; Miller K G; Scheller R H; Khaner H; Lopez J; Smith B L
p65 fragments, homologous to the C2 region of protein kinase C, bind to the intracellular receptors for protein kinase C.
Biochemistry 1992;31(35):8120-4.
1991: Mochly-Rosen D; Khaner H; Lopez J; Smith B L
Intracellular receptors for activated protein kinase C. Identification of a binding site for the enzyme.
The Journal of biological chemistry 1991;266(23):14866-8.
1991: Mochly-Rosen D; Khaner H; Lopez J
Identification of intracellular receptor proteins for activated protein kinase C.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(9):3997-4000.
1990: Mochly-Rosen D; Gordon A S
GTP-binding proteins are restricted to signal transduction sites.
Biochemical and biophysical research communications 1990;173(1):388-95.
1990: Mochly-Rosen D; Henrich C J; Cheever L; Khaner H; Simpson P C
A protein kinase C isozyme is translocated to cytoskeletal elements on activation.
Cell regulation 1990;1(9):693-706.
1988: Mochly-Rosen D; Chang F H; Cheever L; Kim M; Diamond I; Gordon A S
Chronic ethanol causes heterologous desensitization of receptors by reducing alpha s messenger RNA.
Nature 1988;333(6176):848-50.
1985: Souroujon M C; Pizzighella S; Mochly-Rosen D; Fuchs S
Antigenic specificity of acetylcholine receptor in developing muscle. Studies with monoclonal antibodies.
Journal of neuroimmunology 1985;8(2-3):159-66.
1983: Pizzighella S; Gordon A S; Souroujon M C; Mochly-Rosen D; Sharp A; Fuchs S
An anti-acetylcholine receptor monoclonal antibody cross-reacts with phosvitin.
FEBS letters 1983;159(1-2):246-50.
1983: Souroujon M C; Mochly-Rosen D; Gordon A S; Fuchs S
Interaction of monoclonal antibodies to Torpedo acetylcholine receptor with the receptor of skeletal muscle.
Muscle & nerve 1983;6(4):303-11.

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