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Mauro Modesti

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Publications

TOP 3
Graeme A King; Mauro Modesti; Ulrich Bockelmann; Peter Gross; Gijs J L Wuite; Erwin J G Peterman
Revealing the competition between peeled ssDNA, melting bubbles, and S-DNA during DNA overstretching using fluorescence microscopy.
Sara N Andres; Mauro Modesti; Dejan Ristic; Alexandra Vergnes; Claire Wyman; Murray S Junop
A human XRCC4-XLF complex bridges DNA.
J T Holthausen; Roland Kanaar; Mauro Modesti; Dejan Ristic; H Sanchez; M T J van Loenhout; S E van Rossum-Fikkert; Cees Dekker; Claire Wyman
Effect of the BRCA2 CTRD domain on RAD51 filaments analyzed by an ensemble of single molecule techniques.

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All Publications

2013: Graeme A King; Mauro Modesti; Ulrich Bockelmann; Peter Gross; Gijs J L Wuite; Erwin J G Peterman
Revealing the competition between peeled ssDNA, melting bubbles, and S-DNA during DNA overstretching using fluorescence microscopy.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(10):3859-64.
2012: Sara N Andres; Mauro Modesti; Dejan Ristic; Alexandra Vergnes; Claire Wyman; Murray S Junop
A human XRCC4-XLF complex bridges DNA.
Nucleic acids research 2012;40(4):1868-78.
2011: J T Holthausen; Roland Kanaar; Mauro Modesti; Dejan Ristic; H Sanchez; M T J van Loenhout; S E van Rossum-Fikkert; Cees Dekker; Claire Wyman
Effect of the BRCA2 CTRD domain on RAD51 filaments analyzed by an ensemble of single molecule techniques.
Nucleic acids research 2011;39(15):6558-67.
2009: Joost van Mameren; Peter Gross; Geraldine Farge; Pleuni Hooijman; Mauro Modesti; Maria Falkenberg; Gijs J L Wuite; Erwin J G Peterman
Unraveling the structure of DNA during overstretching by using multicolor, single-molecule fluorescence imaging.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(43):18231-6.
2009: Peï-Yu Wu; Philippe Frit; SriLakshmi Meesala; Stéphanie Dauvillier; Mauro Modesti; Sara N Andres; Ying Huang; JoAnn Sekiguchi; Patrick Calsou; bernard salles; Murray S Junop
Structural and functional interaction between the human DNA repair proteins DNA ligase IV and XRCC4.
Molecular and cellular biology 2009;29(11):3163-72.
2009: Joost van Mameren; Mauro Modesti; Roland Kanaar; Claire Wyman; Erwin J G Peterman; Gijs J L Wuite
Counting RAD51 proteins disassembling from nucleoprotein filaments under tension.
Nature 2009;457(7230):745-8.
2008: Thijn van Der Heijden; Mauro Modesti; Susanne Hage; Roland Kanaar; Claire Wyman; Cees Dekker
Homologous recombination in real time: DNA strand exchange by RecA.
Molecular cell 2008;30(4):530-8.
2007: Sara N Andres; Mauro Modesti; Chun J Tsai; Gilbert Chu; Murray S Junop
Crystal structure of human XLF: a twist in nonhomologous DNA end-joining.
Molecular cell 2007;28(6):1093-101.
2007: Mauro Modesti; Magda Budzowska; Céline Baldeyron; Jeroen A A Demmers; Rodolfo Ghirlando; Roland Kanaar
RAD51AP1 is a structure-specific DNA binding protein that stimulates joint molecule formation during RAD51-mediated homologous recombination.
Molecular cell 2007;28(3):468-81.
2007: Ilya Grigoriev; Daniël Splinter; Nanda Keijzer; Phebe Wulf; Jeroen A A Demmers; Toshihisa Ohtsuka; Mauro Modesti; Ivan V Maly; Frank Grosveld; Casper C Hoogenraad; Anna Akhmanova
Rab6 regulates transport and targeting of exocytotic carriers.
Developmental cell 2007;13(2):305-14.
2007: Mauro Modesti; Dejan Ristic; Thijn van Der Heijden; Cees Dekker; Joost van Mameren; Erwin J G Peterman; Gijs J L Wuite; Roland Kanaar; Claire Wyman
Fluorescent human RAD51 reveals multiple nucleation sites and filament segments tightly associated along a single DNA molecule.
Structure (London, England : 1993) 2007;15(5):599-609.
2007: Thijn van Der Heijden; Ralf Seidel; Mauro Modesti; Roland Kanaar; Claire Wyman; Cees Dekker
Real-time assembly and disassembly of human RAD51 filaments on individual DNA molecules.
Nucleic acids research 2007;35(17):5646-57.
2006: Pierre-Olivier Mari; Bogdan I Florea; Stephan P Persengiev; Nicole S Verkaik; Hennie T Brüggenwirth; Mauro Modesti; Giuseppina Giglia-Mari; Karel Bezstarosti; Jeroen A A Demmers; Theo M Luider; Adriaan B Houtsmuller; Dik C van Gent
Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(49):18597-602.
2006: Katsuhiro Hanada; Magda Budzowska; Mauro Modesti; Alex Maas; Claire Wyman; Jeroen Essers; Roland Kanaar
The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks.
The EMBO journal 2006;25(20):4921-32.
2006: Joost van Mameren; Mauro Modesti; Roland Kanaar; Claire Wyman; Gijs J L Wuite; Erwin J G Peterman
Dissecting elastic heterogeneity along DNA molecules coated partly with Rad51 using concurrent fluorescence microscopy and optical tweezers.
Biophysical journal 2006;91(8):L78-80.
2005: Dejan Ristic; Mauro Modesti; Thijn van Der Heijden; John van Noort; Cees Dekker; Roland Kanaar; Claire Wyman
Human Rad51 filaments on double- and single-stranded DNA: correlating regular and irregular forms with recombination function.
Nucleic acids research 2005;33(10):3292-302.
2004: Gideon Lansbergen; Yulia Komarova; Mauro Modesti; Claire Wyman; Casper C Hoogenraad; Holly V Goodson; Régis P Lemaitre; David N Drechsel; Erik van Munster; Theodorus W J Gadella; Frank Grosveld; Niels Galjart; Gary G Borisy; Anna Akhmanova
Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization.
The Journal of cell biology 2004;166(7):1003-14.
2003: Mauro Modesti; Murray S Junop; Rodolfo Ghirlando; Mandy W M M van de Rakt; Martin Gellert; WEI YANG; Roland Kanaar
Tetramerization and DNA ligase IV interaction of the DNA double-strand break repair protein XRCC4 are mutually exclusive.
Journal of molecular biology 2003;334(2):215-28.
2003: Dejan Ristic; Mauro Modesti; Roland Kanaar; Claire Wyman
Rad52 and Ku bind to different DNA structures produced early in double-strand break repair.
Nucleic acids research 2003;31(18):5229-37.
2001: Mauro Modesti; Roland Kanaar
DNA repair: spot(light)s on chromatin.
Current biology : CB 2001;11(6):R229-32.
2001: Martijn de Jager; Mies L G Dronkert; Mauro Modesti; Cecile E M T Beerens; Roland Kanaar; Dik C van Gent
DNA-binding and strand-annealing activities of human Mre11: implications for its roles in DNA double-strand break repair pathways.
Nucleic acids research 2001;29(6):1317-25.
2001: Mauro Modesti; Roland Kanaar
Homologous recombination: from model organisms to human disease.
Genome biology 2001;2(5):REVIEWS1014.
2000: Murray S Junop; Mauro Modesti; Alba Guarné; Rodolfo Ghirlando; Martin Gellert; WEI YANG
Crystal structure of the Xrcc4 DNA repair protein and implications for end joining.
The EMBO journal 2000;19(22):5962-70.
1999: Mauro Modesti; Joanne E Hesse; Martin Gellert
DNA binding of Xrcc4 protein is associated with V(D)J recombination but not with stimulation of DNA ligase IV activity.
The EMBO journal 1999;18(7):2008-18.
1999: Martin Gellert; Joanne E Hesse; K Hiom; Meni Melek; Mauro Modesti; Tanya T Paull; Dale A Ramsden; Dik C van Gent
V(D)J recombination: links to transposition and double-strand break repair.
Cold Spring Harbor symposia on quantitative biology 1999;64():161-7.