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Karin Moelling

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Anatomy

Cell Line

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Molecular Sequence Data

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HIV-1

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Ulrich Nübel; Brar Piening; Wolfgang Witte; Michael Behnke; Justus Benzler; Felix Bröcker; Christoph Bührer; Manuel Dehnert; Gerhard Falkenhorst; Petra Gastmeier; Jochen Hecht; Michael Kube; Franziska Layer; Karin Moelling; Matthias Nachtnebel; Tim Eckmanns
MRSA transmission on a neonatal intensive care unit: epidemiological and genome-based phylogenetic analyses.
Karin Moelling
Are viruses our oldest ancestors?
Felix Broecker; Karsten Andrae; Karin Moelling
Premature activation of the HIV RNase H drives the virus into suicide: a novel microbicide?

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All Publications

2013: Ulrich Nübel; Brar Piening; Wolfgang Witte; Michael Behnke; Justus Benzler; Felix Bröcker; Christoph Bührer; Manuel Dehnert; Gerhard Falkenhorst; Petra Gastmeier; Jochen Hecht; Michael Kube; Franziska Layer; Karin Moelling; Matthias Nachtnebel; Tim Eckmanns
MRSA transmission on a neonatal intensive care unit: epidemiological and genome-based phylogenetic analyses.
PloS one 2013;8(1):e54898.
2012: Karin Moelling
Are viruses our oldest ancestors?
EMBO reports 2012;13(12):1033.
2012: Felix Broecker; Karsten Andrae; Karin Moelling
Premature activation of the HIV RNase H drives the virus into suicide: a novel microbicide?
AIDS research and human retroviruses 2012;28(11):1397-403.
2012: Karin Moelling
Targeting the retroviral ribonuclease H by rational drug design.
AIDS (London, England) 2012;26(16):1983-93.
2012: Felix Broecker; Karin Moelling
Short hairpin-looped oligodeoxynucleotides reduce hepatitis C virus replication.
Virology journal 2012;9():134.
2012: Jochen Heinrich; Dominique Schols; Karin Moelling
A short hairpin loop-structured oligodeoxynucleotide targeting the virion-associated RNase H of HIV inhibits HIV production in cell culture and in huPBL-SCID mice.
Intervirology 2012;55(3):242-6.
2009: Martin Baumgartner; Andreas Weiss; Thorsten Fritzius; Jochen Heinrich; Karin Moelling
The PDZ protein MPP2 interacts with c-Src in epithelial cells.
Experimental cell research 2009;315(17):2888-98.
2009: Marco H Hofmann; Jochen Heinrich; Gerald Radziwill; Gerald Radziwil; Karin Moelling
A short hairpin DNA analogous to miR-125b inhibits C-Raf expression, proliferation, and survival of breast cancer cells.
Molecular cancer research : MCR 2009;7(10):1635-44.
2009: Terry Kwok; Jochen Heinrich; Jiunshan Jung-Shiu; Michelle G Meier; Srikanth Mathur; Karin Moelling
Reduction of gene expression by a hairpin-loop structured oligodeoxynucleotide: alternative to siRNA and antisense.
Biochimica et biophysica acta 2009;1790(10):1170-8.
2009: Faiza Noreen; Jochen Heinrich; Karin Moelling
Antitumor activity of small double-stranded oligodeoxynucleotides targeting telomerase RNA in malignant melanoma cells.
Oligonucleotides 2009;19(2):169-78.
2009: Lina Wittmer-Elzaouk; Jiunshan Jung-Shiu; Jochen Heinrich; Karin Moelling
Retroviral self-inactivation in the mouse vagina induced by short DNA.
Antiviral research 2009;82(1):22-8.
2009: Alexey A Matskevich; Jiun-Shan Jung; Michael Schümann; Manel Cascallo; Karin Moelling
Vero cells as a model to study the effects of adenoviral gene delivery vectors on the RNAi system in context of viral infection.
Journal of innate immunity 2009;1(4):389-94.
2009: Alexander Falkenhagen; Jochen Heinrich; Karin Moelling
Short hairpin-loop-structured oligodeoxynucleotides reduce HSV-1 replication.
Virology journal 2009;6():43.
2009: Terry Kwok; Hanspeter Helfer; Mohammad Intakhab Alam; Jochen Heinrich; Jovan Pavlovic; Karin Moelling
Inhibition of influenza A virus replication by short double-stranded oligodeoxynucleotides.
Archives of virology 2009;154(1):109-14.
2008: Alexey A Matskevich; Karin Moelling
Stimuli-dependent cleavage of Dicer during apoptosis.
The Biochemical journal 2008;412(3):527-34.
2008: Thorsten Fritzius; Karin Moelling
Akt- and Foxo1-interacting WD-repeat-FYVE protein promotes adipogenesis.
The EMBO journal 2008;27(9):1399-410.
2008: Angelika Ress; Karin Moelling
The PDZ protein erbin modulates beta-catenin-dependent transcription.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 2008;41(3):284-9.
2008: Martin Baumgartner; Gerald Radziwill; Mihaela Lorger; Andreas Weiss; Karin Moelling
c-Src-mediated epithelial cell migration and invasion regulated by PDZ binding site.
Molecular and cellular biology 2008;28(2):642-55.
2007: Prisca Boisguerin; Bernhard Ay; Gerald Radziwill; Rafael D Fritz; Karin Moelling; Rudolf Volkmer
Characterization of a putative phosphorylation switch: adaptation of SPOT synthesis to analyze PDZ domain regulation mechanisms.
Chembiochem : a European journal of chemical biology 2007;8(18):2302-7.
2007: Johanna Keyser; Mihaela Lorger; Jovan Pavlovic; Gerald Radziwill; Karin Moelling
Role of AF6 protein in cell-to-cell spread of Herpes simplex virus 1.
FEBS letters 2007;581(28):5349-54.
2007: Andreas Weiss; Martin Baumgartner; Gerald Radziwill; Julia Dennler; Karin Moelling
c-Src is a PDZ interaction partner and substrate of the E3 ubiquitin ligase Ligand-of-Numb protein X1.
FEBS letters 2007;581(26):5131-6.
2007: Elisabeth Ortner; Karin Moelling
Heteromeric complex formation of ASK2 and ASK1 regulates stress-induced signaling.
Biochemical and biophysical research communications 2007;362(2):454-9.
2007: Alexey A Matskevich; Karin Moelling
Dicer is involved in protection against influenza A virus infection.
The Journal of general virology 2007;88(Pt 10):2627-35.
2007: Nurguel Usluoglu; Jovan Pavlovic; Karin Moelling; Gerald Radziwill
RIP2 mediates LPS-induced p38 and IkappaBalpha signaling including IL-12 p40 expression in human monocyte-derived dendritic cells.
European journal of immunology 2007;37(8):2317-25.
2007: Gerald Radziwill; Andreas Weiss; Jochen Heinrich; Martin Baumgartner; Prisca Boisguerin; Koji Owada; Karin Moelling
Regulation of c-Src by binding to the PDZ domain of AF-6.
The EMBO journal 2007;26(11):2633-44.
2007: Kathrin Matzen; Lina Elzaouk; Alexey A Matskevich; Anja Nitzsche; Jochen Heinrich; Karin Moelling
RNase H-mediated retrovirus destruction in vivo triggered by oligodeoxynucleotides.
Nature biotechnology 2007;25(6):669-74.
2007: Thorsten Fritzius; Alexander D Frey; Marc Schweneker; Daniel Mayer; Karin Moelling
WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta.
The FEBS journal 2007;274(6):1552-66.
2006: Alexey A Matskevich; Algirdas Ziogas; Jochen Heinrich; Sandra A Quast; Karin Moelling
Short partially double-stranded oligodeoxynucleotide induces reverse transcriptase/RNase H-mediated cleavage of HIV RNA and contributes to abrogation of infectivity of virions.
AIDS research and human retroviruses 2006;22(12):1220-30.
2006: Lina Elzaouk; Karin Moelling; Jovan Pavlovic
Anti-tumor activity of mesenchymal stem cells producing IL-12 in a mouse melanoma model.
Experimental dermatology 2006;15(11):865-74.
2006: Thorsten Fritzius; Gabriela Burkard; Elvira Haas; Jochen Heinrich; Marc Schweneker; Magnus Bosse; Sven Zimmermann; Alexander D Frey; Antje Caelers; André S Bachmann; Karin Moelling
A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambda.
The Biochemical journal 2006;399(1):9-20.
2006: Mihaela Lorger; Karin Moelling
Regulation of epithelial wound closure and intercellular adhesion by interaction of AF6 with actin cytoskeleton.
Journal of cell science 2006;119(Pt 16):3385-98.
2006: Lina Elzaouk; Jovan Pavlovic; Karin Moelling
Analysis of antitumor activity elicited by vaccination with combinations of interleukin-12 DNA with gp100 DNA or the chemokine CCL21 in vivo.
Human gene therapy 2006;17(8):859-70.
2006: Karin Moelling; Susanne Abels; Joerg Jendis; Alexey A Matskevich; Jochen Heinrich
Silencing of HIV by hairpin-loop-structured DNA oligonucleotide.
FEBS letters 2006;580(14):3545-50.
2006: Mangesh Joshi; Carolyn Vargas; Prisca Boisguerin; Anne Diehl; Gerd Krause; Peter Schmieder; Karin Moelling; Volker Hagen; Markus Schade; Hartmut Oschkinat
Discovery of low-molecular-weight ligands for the AF6 PDZ domain.
Angewandte Chemie (International ed. in English) 2006;45(23):3790-5.
2006: Angelika Ress; Karin Moelling
Bcr interferes with beta-catenin-Tcf1 interaction.
FEBS letters 2006;580(5):1227-30.
2006: Karin Moelling; Alexey A Matskevich; J-S Jung
Relationship between retroviral replication and RNA interference machineries.
Cold Spring Harbor symposia on quantitative biology 2006;71():365-8.
2006: Angelika Ress; Karin Moelling
Interaction partners of the PDZ domain of erbin.
Protein and peptide letters 2006;13(9):877-81.
2005: Angelika Ress; Karin Moelling
Bcr is a negative regulator of the Wnt signalling pathway.
EMBO reports 2005;6(11):1095-100.
2005: Algirdas Ziogas; Karin Moelling; Gerald Radziwill
CNK1 is a scaffold protein that regulates Src-mediated Raf-1 activation.
The Journal of biological chemistry 2005;280(25):24205-11.
2005: Marc Schweneker; André S Bachmann; Karin Moelling
JM4 is a four-transmembrane protein binding to the CCR5 receptor.
FEBS letters 2005;579(7):1751-8.
2005: Lucie Heinzerling; Günter Burg; Reinhard Dummer; Tanja Maier; Patrick A Oberholzer; Jan Schultz; Lina Elzaouk; Jovan Pavlovic; Karin Moelling
Intratumoral injection of DNA encoding human interleukin 12 into patients with metastatic melanoma: clinical efficacy.
Human gene therapy 2005;16(1):35-48.
2004: Marc Schweneker; André S Bachmann; Karin Moelling
The HIV-1 co-receptor CCR5 binds to alpha-catenin, a component of the cellular cytoskeleton.
Biochemical and biophysical research communications 2004;325(3):751-7.
2004: Urs Wiedemann; Prisca Boisguerin; Rainer Leben; Dietmar Leitner; Gerd Krause; Karin Moelling; Rudolf Volkmer-Engert; Hartmut Oschkinat
Quantification of PDZ domain specificity, prediction of ligand affinity and rational design of super-binding peptides.
Journal of molecular biology 2004;343(3):703-18.
2004: Jan G Schiltz; Ulrich Salzer; M Hasan Mohajeri; Daniel Franke; Jochen Heinrich; Jovan Pavlovic; M Axel Wollmer; Roger M Nitsch; Karin Moelling
Antibodies from a DNA peptide vaccination decrease the brain amyloid burden in a mouse model of Alzheimer's disease.
Journal of molecular medicine (Berlin, Germany) 2004;82(10):706-14.
2004: Thomas Pap; Michael Nawrath; Jochen Heinrich; Magnus Bosse; Anja Baier; Klaus M Hummel; Peter Petrow; Stefan Kuchen; Beat A Michel; Renate E Gay; Ulf Müller-Ladner; Karin Moelling; Steffen Gay
Cooperation of Ras- and c-Myc-dependent pathways in regulating the growth and invasiveness of synovial fibroblasts in rheumatoid arthritis.
Arthritis and rheumatism 2004;50(9):2794-802.
2004: Johanna Keyser; Jan Schultz; Kristin Ladell; Lina Elzaouk; Lucie Heinzerling; Jovan Pavlovic; Karin Moelling
IP-10-encoding plasmid DNA therapy exhibits anti-tumor and anti-metastatic efficiency.
Experimental dermatology 2004;13(6):380-90.
2004: Prisca Boisguerin; Rainer Leben; Bernhard Ay; Gerald Radziwill; Karin Moelling; Liying Dong; Rudolf Volkmer-Engert
An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies.
Chemistry & biology 2004;11(4):449-59.
2003: Gerald Radziwill; R A Erdmann; U Margelisch; Karin Moelling
The Bcr kinase downregulates Ras signaling by phosphorylating AF-6 and binding to its PDZ domain.
Molecular and cellular biology 2003;23(13):4663-72.
2003: Kristin Ladell; Jochen Heinrich; Marc Schweneker; Karin Moelling
A combination of plasmid DNAs encoding murine fetal liver kinase 1 extracellular domain, murine interleukin-12, and murine interferon-gamma inducible protein-10 leads to tumor regression and survival in melanoma-bearing mice.
Journal of molecular medicine (Berlin, Germany) 2003;81(4):271-8.
2002: Jochen Heinrich; Jan Schultz; Magnus Bosse; Günter Ziegelin; Erich Lanka; Karin Moelling
Linear closed mini DNA generated by the prokaryotic cleaving-joining enzyme TelN is functional in mammalian cells.
Journal of molecular medicine (Berlin, Germany) 2002;80(10):648-54.
2002: Karin Moelling; Karen Schad; Magnus Bosse; Sven Zimmermann; Marc Schweneker
Regulation of Raf-Akt Cross-talk.
The Journal of biological chemistry 2002;277(34):31099-106.
2002: Lucie Heinzerling; Reinhard Dummer; Jovan Pavlovic; Jan Schultz; Günter Burg; Karin Moelling
Tumor regression of human and murine melanoma after intratumoral injection of IL-12-encoding plasmid DNA in mice.
Experimental dermatology 2002;11(3):232-40.
2001: Hans Peter Reusch; S Zimmermann; Michael Schaefer; Martin Paul; Karin Moelling
Regulation of Raf by Akt controls growth and differentiation in vascular smooth muscle cells.
The Journal of biological chemistry 2001;276(36):33630-7.
2001: Michael Nawrath; Jovan Pavlovic; Karin Moelling
Synergistic effect of a combined DNA and peptide vaccine against gp100 in a malignant melanoma mouse model.
Journal of molecular medicine (Berlin, Germany) 2001;79(2-3):133-42.
2001: Lucie Heinzerling; Karsten Feige; Stefan Rieder; Margarete K Akens; R Dummer; Gerald Stranzinger; Karin Moelling
Tumor regression induced by intratumoral injection of DNA coding for human interleukin 12 into melanoma metastases in gray horses.
Journal of molecular medicine (Berlin, Germany) 2001;78(12):692-702.
2000: Jan Schultz; Lucie Heinzerling; Jovan Pavlovic; Karin Moelling
Induction of long-lasting cytokine effect by injection of IL-12 encoding plasmid DNA.
Cancer gene therapy 2000;7(12):1557-65.
2000: Michael Nawrath; Jovan Pavlovic; Karin Moelling
Inhibition of human hematopoietic tumor formation by targeting a repressor Myb-KRAB to DNA.
Cancer gene therapy 2000;7(6):963-72.
2000: T Heinicke; Gerald Radziwill; Michael Nawrath; C Rommel; Jovan Pavlovic; Karin Moelling
Retroviral gene transfer of dominant negative raf-1 mutants suppresses ha-ras-induced transformation and delays tumor formation.
Cancer gene therapy 2000;7(5):697-706.
2000: Jochen Heinrich; B Strack; Michael Nawrath; Jovan Pavlovic; Karin Moelling
Immunization with Naked DNA Coexpressing Antigen and Cytokine via IRES.
Methods in molecular medicine 2000;29():335-44.
2000: Jochen Heinrich; Magnus Bosse; Holger Eickhoff; Wilfried Nietfeld; R Reinhardt; H Lehrach; Karin Moelling
Induction of putative tumor-suppressing genes in Rat-1 fibroblasts by oncogenic Raf-1 as evidenced by robot-assisted complex hybridization.
Journal of molecular medicine (Berlin, Germany) 2000;78(7):380-8.
2000: K Kasono; Y Heike; Jialing Xiang; Alain Piché; Hyung-Gyoon Kim; M Kim; M Hagiwara; Michael Nawrath; Karin Moelling; David T Curiel
Tetracycline-induced expression of an anti-c-Myb single-chain antibody and its inhibitory effect on proliferation of the human leukemia cell line K562.
Cancer gene therapy 2000;7(1):151-9.
1999: Sven Zimmermann; Karin Moelling
Phosphorylation and regulation of Raf by Akt (protein kinase B).
Science (New York, N.Y.) 1999;286(5445):1741-4.
1999: C Rommel; Brian A Clarke; Sven Zimmermann; L Nuñez; R Rossman; K Reid; Karin Moelling; George D Yancopoulos; David J Glass
Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.
Science (New York, N.Y.) 1999;286(5445):1738-41.
1999: T Schuh; Jan Schultz; Karin Moelling; Jovan Pavlovic
DNA-based vaccine against La Crosse virus: protective immune response mediated by neutralizing antibodies and CD4+ T cells.
Human gene therapy 1999;10(10):1649-58.
1999: E Operschall; T Schuh; Lucie Heinzerling; Jovan Pavlovic; Karin Moelling
Enhanced protection against viral infection by co-administration of plasmid DNA coding for viral antigen and cytokines in mice.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 1999;13(1-2):17-27.
1999: Michael Nawrath; Jovan Pavlovic; R Dummet; Jan Schultz; B Strack; Jochen Heinrich; Karin Moelling
Reduced melanoma tumor formation in mice immunized with DNA expressing the melanoma-specific antigen gp100/pmel17.
Leukemia 1999;13 Suppl 1():S48-51.
1999: Jan Schultz; Jovan Pavlovic; B Strack; Michael Nawrath; Karin Moelling
Long-lasting anti-metastatic efficiency of interleukin 12-encoding plasmid DNA.
Human gene therapy 1999;10(3):407-17.
1999: S Schneider; Michael Buchert; Oleg Georgiev; Bruno Catimel; Michael M Halford; S A Stacker; Thomas Baechi; Karin Moelling; Christopher M Hovens
Mutagenesis and selection of PDZ domains that bind new protein targets.
Nature biotechnology 1999;17(2):170-5.
1999: Michael Buchert; S Schneider; Virginia Meskenaite; MT Adams; E Canaani; Thomas Baechi; Karin Moelling; Christopher M Hovens
The junction-associated protein AF-6 interacts and clusters with specific Eph receptor tyrosine kinases at specialized sites of cell-cell contact in the brain.
The Journal of cell biology 1999;144(2):361-71.
1998: K Kasono; Alain Piché; Jialing Xiang; Hyung-Gyoon Kim; G Bilbao; F Johanning; Michael Nawrath; Karin Moelling; David T Curiel
Functional knock-out of c-myb by an intracellular anti-c-Myb single-chain antibody.
Biochemical and biophysical research communications 1998;251(1):124-30.
1998: Algirdas Ziogas; I C Lorenz; Karin Moelling; Gerald Radziwill
Mitotic Raf-1 is stimulated independently of Ras and is active in the cytoplasm.
The Journal of biological chemistry 1998;273(37):24108-14.
1998: J Jendis; B Strack; Karin Moelling
Inhibition of replication of drug-resistant HIV type 1 isolates by polypurine tract-specific oligodeoxynucleotide TFO A.
AIDS research and human retroviruses 1998;14(11):999-1005.
1998: André S Bachmann; A Surovoy; G Jung; Karin Moelling
Integrin receptor-targeted transfer peptides for efficient delivery of antisense oligodeoxynucleotides.
Journal of molecular medicine (Berlin, Germany) 1998;76(2):126-32.
1998: Michael Nawrath; Jochen Heinrich; B Strack; Jovan Pavlovic; Karin Moelling
A DNA vaccine against malignant melanoma coexpressing antigen and cytokine.
Advances in experimental medicine and biology 1998;451():305-10.
1997: Thierry Dubois; C Rommel; Steven Howell; U Steinhussen; Yasmina Soneji; N Morrice; Karin Moelling; Alastair Aitken
14-3-3 is phosphorylated by casein kinase I on residue 233. Phosphorylation at this site in vivo regulates Raf/14-3-3 interaction.
The Journal of biological chemistry 1997;272(46):28882-8.
1997: Sven Zimmermann; C Rommel; Algirdas Ziogas; J Lovric; Karin Moelling; Gerald Radziwill
MEK1 mediates a positive feedback on Raf-1 activity independently of Ras and Src.
Oncogene 1997;15(13):1503-11.
1997: S Schneider; Oleg Georgiev; Michael Buchert; MT Adams; Karin Moelling; Christopher M Hovens
An epitope tagged mammalian/prokaryotic expression vector with positive selection of cloned inserts.
Gene 1997;197(1-2):337-41.
1997: Michael Buchert; S Schneider; MT Adams; Hans Peter Hefti; Karin Moelling; Christopher M Hovens
Useful vectors for the two-hybrid system in mammalian cells.
BioTechniques 1997;23(3):396-8, 400, 402.
1997: Karin Moelling
DNA for genetic vaccination and therapy.
Cytokines, cellular & molecular therapy 1997;3(2):127-35.
1997: C Rommel; Gerald Radziwill; Karin Moelling; Ernst Hafen
Negative regulation of Raf activity by binding of 14-3-3 to the amino terminus of Raf in vivo.
Mechanisms of development 1997;64(1-2):95-104.
1996: G Vorbrueggen; J Lovrić; Karin Moelling
Functional analysis of phosphorylation at serine 532 of human c-Myb by MAP kinase.
Biological chemistry 1996;377(11):721-30.
1996: Gerald Radziwill; U Steinhusen; A Aitken; Karin Moelling
Inhibition of Raf/MAPK signaling in Xenopus oocyte extracts by Raf-1-specific peptides.
Biochemical and biophysical research communications 1996;227(1):20-6.
1996: Jovan Pavlovic; Michael Nawrath; R Tu; T Heinicke; Karin Moelling
Anti-tumor immunity is involved in the thymidine kinase-mediated killing of tumors induced by activated Ki-ras(G12V).
Gene therapy 1996;3(7):635-43.
1996: J Lovrić; Gerald Radziwill; Karin Moelling
Specific association of Mil/Raf proteins with a 34 kDa phosphoprotein.
Oncogene 1996;12(5):1145-51.
1996: J Lovrić; Karin Moelling
Activation of Mil/Raf protein kinases in mitotic cells.
Oncogene 1996;12(5):1109-16.
1996: C Rommel; Gerald Radziwill; J Lovrić; J Noeldeke; T Heinicke; D Jones; A Aitken; Karin Moelling
Activated Ras displaces 14-3-3 protein from the amino terminus of c-Raf-1.
Oncogene 1996;12(3):609-19.
1996: E Schmalzbauer; B Strack; J Dannull; S Guehmann; Karin Moelling
Mutations of basic amino acids of NCp7 of human immunodeficiency virus type 1 affect RNA binding in vitro.
Journal of virology 1996;70(2):771-7.
1996: Karin Moelling; B Strack; Gerald Radziwill
Signal transduction as target of gene therapy.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1996;142():63-71.
1995: W Nürnberg; Metin Artuc; M Nawrath; J Lovric; S Stüting; Karin Moelling; B M Czarnetzki; Dirk Schadendorf
Human c-myb is expressed in cervical carcinomas and transactivates the HPV-16 promoter.
Cancer research 1995;55(19):4432-7.
1995: I Goren; O J Semmes; K T Jeang; Karin Moelling
The amino terminus of Tax is required for interaction with the cyclic AMP response element binding protein.
Journal of virology 1995;69(9):5806-11.
1995: W Nürnberg; Metin Artuc; G Vorbrueggen; F Kalkbrenner; Karin Moelling; B M Czarnetzki; Dirk Schadendorf
Nuclear proto-oncogene products transactivate the human papillomavirus type 16 promoter.
British journal of cancer 1995;71(5):1018-24.
1995: S Volkmann; J Jendis; A Frauendorf; Karin Moelling
Inhibition of HIV-1 reverse transcription by triple-helix forming oligonucleotides with viral RNA.
Nucleic acids research 1995;23(7):1204-12.
1995: Gerald Radziwill; M Niehof; C Rommel; Karin Moelling
Direct interaction and N-terminal phosphorylation of c-Jun by c-Mil/Raf.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(5):1421-5.
1995: M Niehof; Gerald Radziwill; S Klauser; Karin Moelling
A small peptide derived from the aminoterminus of c-Raf-1 inhibits c-Raf-1/Ras binding.
Biochemical and biophysical research communications 1995;206(1):46-50.
1994: P Beimling; M Niehof; Gerald Radziwill; Karin Moelling
The aminoterminus of c-Raf-1 binds a protein kinase phosphorylating Ser259.
Biochemical and biophysical research communications 1994;204(2):841-8.
1994: G Müller; B Strack; J Dannull; B S Sproat; A Surovoy; G Jung; Karin Moelling
Amino acid requirements of the nucleocapsid protein of HIV-1 for increasing catalytic activity of a Ki-ras ribozyme in vitro.
Journal of molecular biology 1994;242(4):422-9.
1994: M Niehof; P Beimling; Karin Moelling
The aminoterminus of c-Raf-1 binds a 28-kD cellular protein.
Biochemical and biophysical research communications 1994;203(3):1560-6.
1994: Karin Moelling; G Mueller; J Dannull; C Reuss; P Beimling; C Bartz; B Wiedenmann; K Yoon; A Surovoy; G Jung
Stimulation of Ki-ras ribozyme activity by RNA binding protein, NCp7, in vitro and in pancreatic tumor cell line, capan 1.
Annals of the New York Academy of Sciences 1994;733():113-21.
1994: G Vorbrueggen; F Kalkbrenner; S Guehmann; Karin Moelling
The carboxyterminus of human c-myb protein stimulates activated transcription in trans.
Nucleic acids research 1994;22(13):2466-75.
1994: K Schramm; M Niehof; Gerald Radziwill; C Rommel; Karin Moelling
Phosphorylation of c-Raf-1 by protein kinase A interferes with activation.
Biochemical and biophysical research communications 1994;201(2):740-7.
1994: J Lovrić; O Bischof; Karin Moelling
Cell cycle-dependent association of Gag-Mil and hsp90.
FEBS letters 1994;343(1):15-21.
1994: J Dannull; A Surovoy; G Jung; Karin Moelling
Specific binding of HIV-1 nucleocapsid protein to PSI RNA in vitro requires N-terminal zinc finger and flanking basic amino acid residues.
The EMBO journal 1994;13(7):1525-33.
1993: S Volkmann; B M Wöhrl; M Tisdale; Karin Moelling
Enzymatic analysis of two HIV-1 reverse transcriptase mutants with mutations in carboxyl-terminal amino acid residues conserved among retroviral ribonucleases H.
The Journal of biological chemistry 1993;268(4):2674-83.
1993: A Surovoy; J Dannull; Karin Moelling; G Jung
Conformational and nucleic acid binding studies on the synthetic nucleocapsid protein of HIV-1.
Journal of molecular biology 1993;229(1):94-104.
1992: A Zobel; F Kalkbrenner; G Vorbrueggen; Karin Moelling
Transactivation of the human c-myc gene by c-Myb.
Biochemical and biophysical research communications 1992;186(2):715-22.
1992: S Guehmann; G Vorbrueggen; F Kalkbrenner; Karin Moelling
Reduction of a conserved Cys is essential for Myb DNA-binding.
Nucleic acids research 1992;20(9):2279-86.
1992: P Beimling; Karin Moelling
Direct interaction of CREB protein with 21 bp Tax-response elements of HTLV-ILTR.
Oncogene 1992;7(2):257-62.
1991: B M Wöhrl; S Volkmann; Karin Moelling
Mutations of a conserved residue within HIV-1 ribonuclease H affect its exo- and endonuclease activities.
Journal of molecular biology 1991;220(3):801-18.
1991: A Zobel; F Kalkbrenner; S Guehmann; M Nawrath; G Vorbrueggen; Karin Moelling
Interaction of the v-and c-Myb proteins with regulatory sequences of the human c-myc gene.
Oncogene 1991;6(8):1397-407.
1991: B M Wöhrl; Karin Moelling
Coupling of reverse transcriptase and RNase H during HIV-1 replication.
Behring Institute Mitteilungen 1991;(89):100-7.
1991: U Lorenz; Elisabeth Sock; Friedrich Grummt; Karin Moelling
Analysis of DNA sequences present in complexes of v-Myc and cellular DNA.
Oncogene 1991;6(1):51-7.
1991: T Schulze; M Nawrath; Karin Moelling
Cleavage of the HIV-1 p66 reverse transcriptase/RNase H by the p9 protease in vitro generates active p15 RNase H.
Archives of virology 1991;118(3-4):179-88.
1990: B M Wöhrl; Karin Moelling
Interaction of HIV-1 ribonuclease H with polypurine tract containing RNA-DNA hybrids.
Biochemistry 1990;29(44):10141-7.
1990: F Kalkbrenner; S Guehmann; Karin Moelling
Transcriptional activation by human c-myb and v-myb genes.
Oncogene 1990;5(5):657-61.
1990: P Beimling; Karin Moelling
Tax-independent binding of multiple cellular factors to Tax-response element DNA of HTLV-I.
Oncogene 1990;5(3):361-8.
1990: H Bading; Karin Moelling
Transcriptional down-regulation of c-myc expression by protein synthesis-dependent and -independent pathways in a human T lymphoblastic tumor cell line.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1990;1(3):113-7.
1989: Karin Moelling; T Schulze; H Diringer
Inhibition of human immunodeficiency virus type 1 RNase H by sulfated polyanions.
Journal of virology 1989;63(12):5489-91.
1989: H Bading; E W Rauterberg; Karin Moelling
Distribution of c-myc, c-myb, and Ki-67 antigens in interphase and mitotic human cells evidenced by immunofluorescence staining technique.
Experimental cell research 1989;185(1):50-9.
1989: H Bading; C Beutler; Karin Moelling
Mapping of a small phosphopeptide at the carboxyterminus of the viral myb protein by monoclonal antibodies.
Oncogene 1989;4(1):33-8.
1988: S Billich; M T Knoop; J Hansen; P Strop; Juraj Sedlacek; R Mertz; Karin Moelling
Synthetic peptides as substrates and inhibitors of human immune deficiency virus-1 protease.
The Journal of biological chemistry 1988;263(34):17905-8.
1988: H Bading; J Gerdes; R Schwarting; H Stein; Karin Moelling
Nuclear and cytoplasmic distribution of cellular myb protein in human haematopoietic cells evidenced by monoclonal antibody.
Oncogene 1988;3(3):257-65.
1988: J Hansen; S Billich; T Schulze; S Sukrow; Karin Moelling
Partial purification and substrate analysis of bacterially expressed HIV protease by means of monoclonal antibody.
The EMBO journal 1988;7(6):1785-91.
1988: J Hansen; T Schulze; W Mellert; Karin Moelling
Identification and characterization of HIV-specific RNase H by monoclonal antibody.
The EMBO journal 1988;7(1):239-43.
1987: H Bading; C Beutler; P Beimling; J Gerdes; H Stein; Karin Moelling
Monoclonal antibodies against the viral and human cellular myb gene product.
Haematology and blood transfusion 1987;31():488-92.
1987: H Bading; J Hansen; Karin Moelling
Selective DNA binding of the human cellular myb protein isolated by immunoaffinity chromatography using a monoclonal antibody.
Oncogene 1987;1(4):395-401.
1986: Karin Moelling; T Sander; U Lorenz; P Beimling; H Bading
Interaction of the oncogene protein myc with specific DNA fragments.
Journal of cancer research and clinical oncology 1986;112(2):97-9.
1985: P Beimling; T Benter; T Sander; Karin Moelling
Isolation and characterization of the human cellular myc gene product.
Biochemistry 1985;24(23):6349-55.
1985: B Heimann; P Beimling; E Pfaff; H Schaller; Karin Moelling
Analysis of a tyrosine-specific protein kinase activity associated with the retroviral erbB oncogene product.
Experimental cell research 1985;161(1):199-208.
1985: Karin Moelling; E Pfaff; H Beug; P Beimling; T Bunte; H E Schaller; T Graf
DNA-binding activity is associated with purified myb proteins from AMV and E26 viruses and is temperature-sensitive for E26 ts mutants.
Cell 1985;40(4):983-90.
1985: T Benter; P Beimling; E Pfaff; T Sander; B Heimann; Karin Moelling
Identification of the human cellular myc gene product by antibody against the bacterially expressed protein.
Haematology and blood transfusion 1985;29():266-8.
1984: Karin Moelling; B Heimann; P Beimling; U R Rapp; T Sander
Serine- and threonine-specific protein kinase activities of purified gag-mil and gag-raf proteins.
Nature 1984;312(5994):558-61.
1984: T Bunte; P Donner; E Pfaff; B Reis; Irene Greiser-Wilke; H Schaller; Karin Moelling
Inhibition of DNA binding of purified p55v-myc in vitro by antibodies against bacterially expressed myc protein and a synthetic peptide.
The EMBO journal 1984;3(8):1919-24.
1984: Karin Moelling; T Benter; T Bunte; E Pfaff; W Deppert; J M Egly; N B Miyamoto
Properties of the myc-gene product: nuclear association, inhibition of transcription and activation in stimulated lymphocytes.
Current topics in microbiology and immunology 1984;113():198-207.
1983: P Donner; T Bunte; Irene Greiser-Wilke; Karin Moelling
Decreased DNA-binding ability of purified transformation-specific proteins from deletion mutants of the acute avian leukemia virus MC29.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(10):2861-5.
1983: Karin Moelling; Irene Greiser-Wilke; M K Owada; P Donner; T Bunte
DNA-binding ability of transforming proteins from avian erythroblastosis virus and mutant avian myelocytomatosis virus, MC29, in comparison with MC29 wild type.
Haematology and blood transfusion 1983;28():214-7.
1983: T Bunte; Irene Greiser-Wilke; Karin Moelling
The transforming protein of the MC29-related virus CMII is a nuclear DNA-binding protein whereas MH2 codes for a cytoplasmic RNA-DNA binding polyprotein.
The EMBO journal 1983;2(7):1087-92.
1982: P Donner; Irene Greiser-Wilke; Karin Moelling
Nuclear localization and DNA binding of the transforming gene product of avian myelocytomatosis virus.
Nature 1982;296(5854):262-9.
1982: T Bunte; Irene Greiser-Wilke; P Donner; Karin Moelling
Association of gag-myc proteins from avian myelocytomatosis virus wild-type and mutants with chromatin.
The EMBO journal 1982;1(8):919-27.
1982: Karin Moelling; M K Owada; Irene Greiser-Wilke; T Bunte; P Donner
Biochemical characterization of transformation-specific proteins of acute avian leukemia and sarcoma viruses.
Journal of cellular biochemistry 1982;20(1):63-9.
1981: P Donner; T Bunte; M K Owada; Karin Moelling
Biochemical characterization of pp60src-associated protein kinase from avian sarcoma virus Schmidt-Ruppin strain.
The Journal of biological chemistry 1981;256(16):8786-94.
1981: T Bunte; M K Owada; P Donner; C B Boschek; Karin Moelling
Association of the transformation-specific protein pp60src with the membrane of an avian sarcoma virus.
Journal of virology 1981;38(3):1034-47.
1981: M K Owada; P Donner; A Scott; Karin Moelling
Isolation of an avian sarcoma virus-specific protein kinase from virus particles.
Virology 1981;110(2):333-43.
1981: Karin Moelling; M K Owada; P Donner; T Bunte
The transformation-specific protein pp60src from an avian sarcoma virus.
Haematology and blood transfusion 1981;26():405-8.