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Gabriela Moeslein

Research Profile

Disorders

Chemicals & Drugs

Physiology

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Immunohistochemistry

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Publications

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Christoph Engel; Encarna Gómez García; Timm O Goecke; Heike Goergens; Frederik J Hes; Elke Holinski-Feder; Nicoline Hoogerbrugge; Irma Kluijt; Tom G W Letteboer; Markus Loeffler; Fred H Menko; Gabriela Moeslein; Peter Propping; Nils Rahner; Hans K Schackert; Wolff Schmiegel; Rolf H Sijmons; Verena Steinke; Theo A M van Os; Reinhard Buettner; Wolfgang Dietmaier; Magnus von Knebel Doeberitz; Anja Wagner; Hans F A Vasen
Risks of less common cancers in proven mutation carriers with lynch syndrome.
Bernd Frank; Barbara Burwinkel; Justo Lorenzo Bermejo; Asta Försti; Kari Hemminki; Richard Houlston; Elisabeth Mangold; Nils Rahner; Waltraut Friedl; Nicolaus Friedrichs; Reinhard Buettner; Christoph Engel; Markus Loeffler; Elke Holinski-Feder; Monika Morak; Gisela Keller; Hans K Schackert; Stefan Krüger; Timm Goecke; Gabriela Moeslein; Matthias Kloor; Johannes Gebert; Erdmute Kunstmann; Karsten Schulmann; Josef Rüschoff; Peter Propping
Ten recently identified associations between nsSNPs and colorectal cancer could not be replicated in German families.
Pia Alhopuro; Denis Phichith; Sari Tuupanen; Heli Sammalkorpi; Miranda Nybondas; Juha Saharinen; James P Robinson; Zhaohui Yang; Li-Qiong Chen; Torben Orntoft; Jukka-Pekka Mecklin; Heikki Järvinen; Charis Eng; Gabriela Moeslein; Darryl Shibata; richard Houlston; Anneke Lucassen; Ian P M Tomlinson; Virpi Launonen; Ari Ristimäki; Diego Arango; Auli Karhu; H Lee Sweeney; Lauri A Aaltonen
Unregulated smooth-muscle myosin in human intestinal neoplasia.

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All Publications

2012: Christoph Engel; Encarna Gómez García; Timm O Goecke; Heike Goergens; Frederik J Hes; Elke Holinski-Feder; Nicoline Hoogerbrugge; Irma Kluijt; Tom G W Letteboer; Markus Loeffler; Fred H Menko; Gabriela Moeslein; Peter Propping; Nils Rahner; Hans K Schackert; Wolff Schmiegel; Rolf H Sijmons; Verena Steinke; Theo A M van Os; Reinhard Buettner; Wolfgang Dietmaier; Magnus von Knebel Doeberitz; Anja Wagner; Hans F A Vasen
Risks of less common cancers in proven mutation carriers with lynch syndrome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(35):4409-15.
2008: Bernd Frank; Barbara Burwinkel; Justo Lorenzo Bermejo; Asta Försti; Kari Hemminki; Richard Houlston; Elisabeth Mangold; Nils Rahner; Waltraut Friedl; Nicolaus Friedrichs; Reinhard Buettner; Christoph Engel; Markus Loeffler; Elke Holinski-Feder; Monika Morak; Gisela Keller; Hans K Schackert; Stefan Krüger; Timm Goecke; Gabriela Moeslein; Matthias Kloor; Johannes Gebert; Erdmute Kunstmann; Karsten Schulmann; Josef Rüschoff; Peter Propping
Ten recently identified associations between nsSNPs and colorectal cancer could not be replicated in German families.
Cancer letters 2008;271(1):153-7.
2008: Pia Alhopuro; Denis Phichith; Sari Tuupanen; Heli Sammalkorpi; Miranda Nybondas; Juha Saharinen; James P Robinson; Zhaohui Yang; Li-Qiong Chen; Torben Orntoft; Jukka-Pekka Mecklin; Heikki Järvinen; Charis Eng; Gabriela Moeslein; Darryl Shibata; richard Houlston; Anneke Lucassen; Ian P M Tomlinson; Virpi Launonen; Ari Ristimäki; Diego Arango; Auli Karhu; H Lee Sweeney; Lauri A Aaltonen
Unregulated smooth-muscle myosin in human intestinal neoplasia.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(14):5513-8.
2007: Miguel Abal; Antonia Obrador-Hevia; Klaus-Peter Janssen; Laura Casadome; Mireia Menendez; Sabrina Carpentier; Emmanuel Barillot; Mechthild Wagner; Wilhelm Ansorge; Gabriela Moeslein; Hafida Fsihi; Vladimir Bezrookove; Jaume Reventos; Daniel Louvard; Gabriel Capella; Sylvie Robine
APC inactivation associates with abnormal mitosis completion and concomitant BUB1B/MAD2L1 up-regulation.
Gastroenterology 2007;132(7):2448-58.
2006: Timm Goecke; Karsten Schulmann; Christoph Engel; Elke Holinski-Feder; Constanze Pagenstecher; Hans K Schackert; Matthias Kloor; Erdmute Kunstmann; Holger Vogelsang; Gisela Keller; Wolfgang Dietmaier; Elisabeth Mangold; Nicolaus Friedrichs; Peter Propping; Stefan Krüger; Johannes Gebert; Wolff Schmiegel; Josef Rueschoff; Markus Loeffler; Gabriela Moeslein
Genotype-phenotype comparison of German MLH1 and MSH2 mutation carriers clinically affected with Lynch syndrome: a report by the German HNPCC Consortium.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(26):4285-92.
2006: Steffen Pistorius; Heike Görgens; Stefan Krüger; Christoph Engel; Elisabeth Mangold; Constanze Pagenstecher; Elke Holinski-Feder; Gabriela Moeslein; Magnus von Knebel Doeberitz; Josef Rüschoff; Judith Karner-Hanusch; Hans-Detlev Saeger; Hans K Schackert
N-acetyltransferase (NAT) 2 acetylator status and age of onset in patients with hereditary nonpolyposis colorectal cancer (HNPCC).
Cancer letters 2006;241(1):150-7.
2006: Stefan Krüger; Christoph Engel; Andrea Bier; Elisabeth Mangold; Constanze Pagenstecher; Magnus von Knebel Doeberitz; Elke Holinski-Feder; Gabriela Moeslein; Gisela Keller; Erdmute Kunstmann; Waltraut Friedl; Jens Plaschke; Josef Rüschoff; Hans K Schackert
Absence of association between cyclin D1 (CCND1) G870A polymorphism and age of onset in hereditary nonpolyposis colorectal cancer.
Cancer letters 2006;236(2):191-7.
2006: Christoph Engel; Jochen Forberg; Elke Holinski-Feder; Constanze Pagenstecher; Jens Plaschke; Matthias Kloor; Christopher Poremba; Christian Pox; Josef Rüschoff; Gisela Keller; Wolfgang Dietmaier; Petra Rümmele; Nicolaus Friedrichs; Elisabeth Mangold; Reinhard Buettner; Hans K Schackert; Peter Kienle; Susanne Stemmler; Gabriela Moeslein; Markus Loeffler
Novel strategy for optimal sequential application of clinical criteria, immunohistochemistry and microsatellite analysis in the diagnosis of hereditary nonpolyposis colorectal cancer.
International journal of cancer. Journal international du cancer 2006;118(1):115-22.
2005: Stefan Krüger; Andrea Bier; Christoph Engel; Elisabeth Mangold; Constanze Pagenstecher; Magnus von Knebel Doeberitz; Elke Holinski-Feder; Gabriela Moeslein; Karsten Schulmann; Jens Plaschke; Josef Rüschoff; Hans K Schackert
The p53 codon 72 variation is associated with the age of onset of hereditary non-polyposis colorectal cancer (HNPCC).
Journal of medical genetics 2005;42(10):769-73.
2005: Elisabeth Mangold; Constanze Pagenstecher; Waltraut Friedl; Micaela Mathiak; Reinhard Buettner; Christoph Engel; Markus Loeffler; Elke Holinski-Feder; Yvonne Müller-Koch; Gisela Keller; Hans K Schackert; Stefan Krüger; Timm Goecke; Gabriela Moeslein; Matthias Kloor; Johannes Gebert; Erdmute Kunstmann; Karsten Schulmann; Josef Rüschoff; Peter Propping
Spectrum and frequencies of mutations in MSH2 and MLH1 identified in 1,721 German families suspected of hereditary nonpolyposis colorectal cancer.
International journal of cancer. Journal international du cancer 2005;116(5):692-702.
2005: Irina Drobinskaya; Helmut E Gabbert; Gabriela Moeslein; Wolfram Mueller
A new method for optimizing multiplex DNA microsatellite analysis in low quality archival specimens.
Anticancer research 2005;25(5):3251-8.
2005: Stefan Krüger; Ann-Sophie Silber; Christoph Engel; Heike Görgens; Elisabeth Mangold; Constanze Pagenstecher; Elke Holinski-Feder; Magnus von Knebel Doeberitz; Gabriela Moeslein; Wolfgang Dietmaier; Susanne Stemmler; Waltraut Friedl; Josef Rüschoff; Hans K Schackert
Arg462Gln sequence variation in the prostate-cancer-susceptibility gene RNASEL and age of onset of hereditary non-polyposis colorectal cancer: a case-control study.
The lancet oncology 2005;6(8):566-72.
2005: Valerie Schumacher; Tilman Vogel; Barbara Leube; Christiane Driemel; Timm Goecke; Gabriela Moeslein; Brigitte Royer-Pokora
Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.
Human genetics 2005;116(6):541.
2005: Valerie Schumacher; Tilman Vogel; Barbara Leube; Christiane Driemel; Timm Goecke; Gabriela Moeslein; Brigitte Royer-Pokora
Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.
Human genetics 2005;116(6):540.
2005: Valerie Schumacher; Tilman Vogel; Barbara Leube; Christiane Driemel; Timm Goecke; Gabriela Moeslein; Brigitte Royer-Pokora
Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.
Human genetics 2005;116(6):540.
2005: Valerie Schumacher; Tilman Vogel; Barbara Leube; Christiane Driemel; Timm Goecke; Gabriela Moeslein; Brigitte Royer-Pokora
Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.
Human genetics 2005;116(6):540.
2005: Valerie Schumacher; Tilman Vogel; Barbara Leube; Christiane Driemel; Timm Goecke; Gabriela Moeslein; Brigitte Royer-Polora
Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.
Human genetics 2005;116(6):537.
2005: Valerie Schumacher; Tilman Vogel; Barbara Leube; Christiane Driemel; Timm Goecke; Gabriela Moeslein; Brigitte Royer-Pokora
Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.
Human genetics 2005;116(6):537.
2005: Valerie Schumacher; Tilman Vogel; Barbara Leube; Christiane Driemel; Timm Goecke; Gabriela Moeslein; Brigitte Royer-Polora
Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.
Human genetics 2005;116(6):536.
2005: Valerie Schumacher; Tilman Vogel; Barbara Leube; Christiane Driemel; Timm Goecke; Gabriela Moeslein; Brigitte Royer-Pokora
Gene symbol: STK11. Disease: Peutz-Jeghers syndrome.
Human genetics 2005;116(6):533.
2005: Yansong Bian; Trinidad Caldes; Juul Wijnen; Patrick Franken; H F A Vasen; Virginia G Kaklamani; Khedoudja Nafa; Paolo Peterlongo; Nathan Ellis; John A Baron; John Burn; Gabriela Moeslein; Patrick J Morrison; Yu Chen; Habibul Ahsan; Patrice Watson; Henry T Lynch; Albert de La Chapelle; Riccardo Fodde; Boris Pasche
TGFBR1*6A may contribute to hereditary colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(13):3074-8.
2005: Karsten Schulmann; Frank Brasch; Erdmute Kunstmann; Christoph Engel; Constanze Pagenstecher; Holger Vogelsang; Stefan Krüger; Tilman Vogel; Hanns-Peter Knaebel; Josef Rüschoff; Stephan Hahn; Magnus V Knebel-Doeberitz; Gabriela Moeslein; Meltzer Stephen J.; Hans K Schackert; Christiane Tympner; Elisabeth Mangold; Wolff Schmiegel
HNPCC-associated small bowel cancer: clinical and molecular characteristics.
Gastroenterology 2005;128(3):590-9.
2004: Jens Plaschke; Christoph Engel; Stefan Krüger; Elke Holinski-Feder; Constanze Pagenstecher; Elisabeth Mangold; Gabriela Moeslein; Karsten Schulmann; Johannes Gebert; Magnus von Knebel Doeberitz; Josef Rüschoff; Markus Loeffler; Hans K Schackert
Lower incidence of colorectal cancer and later age of disease onset in 27 families with pathogenic MSH6 germline mutations compared with families with MLH1 or MSH2 mutations: the German Hereditary Nonpolyposis Colorectal Cancer Consortium.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(22):4486-94.
2004: Anika Hansmann; Claudia Adolph; Tilman Vogel; Andreas Unger; Gabriela Moeslein
High-dose tamoxifen and sulindac as first-line treatment for desmoid tumors.
Cancer 2004;100(3):612-20.
2003: Vladimir Bezrookove; Ron Smits; Gabriela Moeslein; Riccardo Fodde; Hans J Tanke; Anton K Raap; Firouz Darroudi
Premature chromosome condensation revisited: a novel chemical approach permits efficient cytogenetic analysis of cancers.
Genes, chromosomes & cancer 2003;38(2):177-86.
2001: Elke Holinski-Feder; Yvonne Müller-Koch; Waltraut Friedl; Gabriela Moeslein; Gisela Keller; Jens Plaschke; W Ballhausen; Manfred Gross; K Baldwin-Jedele; Matthias Jungck; Elisabeth Mangold; Holger Vogelsang; Hans K Schackert; P Lohsea; Jan Murken; Thomas Meitinger
DHPLC mutation analysis of the hereditary nonpolyposis colon cancer (HNPCC) genes hMLH1 and hMSH2.
Journal of biochemical and biophysical methods 2001;47(1-2):21-32.
1997: T Bocker; J Diermann; W Friedl; Johannes Gebert; E Holinski-Feder; Judith Karner-Hanusch; Magnus von Knebel Doeberitz; K Koelble; Gabriela Moeslein; Hans K Schackert; H C Wirtz; Richard Fishel; Josef Rüschoff
Microsatellite instability analysis: a multicenter study for reliability and quality control.
Cancer research 1997;57(21):4739-43.