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Jeremy Mogridge

Research Profile

Chemicals & Drugs

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Anatomy

Genes & Molecular Sequences

Amino Acid Sequences

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Physiology

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Anthrax

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Publications

TOP 3
Kuo-Chieh Liao; Jeremy Mogridge
Activation of the Nlrp1b inflammasome by reduction of cytosolic ATP.
Kristopher M Garlick; Sarah Batty; Jeremy Mogridge
Binding of filamentous actin to anthrax toxin receptor 1 decreases its association with protective antigen.
Bradley C Frew; Vineet R Joag; Jeremy Mogridge
Proteolytic processing of Nlrp1b is required for inflammasome activity.

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All Publications

2013: Kuo-Chieh Liao; Jeremy Mogridge
Activation of the Nlrp1b inflammasome by reduction of cytosolic ATP.
Infection and immunity 2013;81(2):570-9.
2012: Kristopher M Garlick; Sarah Batty; Jeremy Mogridge
Binding of filamentous actin to anthrax toxin receptor 1 decreases its association with protective antigen.
Biochemistry 2012;51(6):1249-56.
2012: Bradley C Frew; Vineet R Joag; Jeremy Mogridge
Proteolytic processing of Nlrp1b is required for inflammasome activity.
PLoS pathogens 2012;8(4):e1002659.
2011: Amit Joshi; Sandesh Kate; Vincent Poon; Dhananjoy Mondal; Mohan B Boggara; Arundhati Saraph; Jacob T Martin; Ryan McAlpine; Ryan Day; Angel Enrique Garcia; Jeremy Mogridge; Ravi S Kane
Structure-based design of a heptavalent anthrax toxin inhibitor.
Biomacromolecules 2011;12(3):791-6.
2010: Stephanie Ngai; Sarah Batty; Kuo-Chieh Liao; Jeremy Mogridge
An anthrax lethal factor mutant that is defective at causing pyroptosis retains proapoptotic activity.
The FEBS journal 2010;277(1):119-27.
2009: Kristopher M Garlick; Jeremy Mogridge
Direct interaction between anthrax toxin receptor 1 and the actin cytoskeleton.
Biochemistry 2009;48(44):10577-81.
2009: Kuo-Chieh Liao; Jeremy Mogridge
Expression of Nlrp1b inflammasome components in human fibroblasts confers susceptibility to anthrax lethal toxin.
Infection and immunity 2009;77(10):4455-62.
2008: Prakash Rai; David Vance; Vincent Poon; Jeremy Mogridge; Ravi S Kane
Stable and potent polyvalent anthrax toxin inhibitors: raft-inspired domain formation in liposomes that contain PEGylated lipids.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(26):7748-51.
2008: Sarah Chapelsky; Sarah Batty; Mia Frost; Jeremy Mogridge
Inhibition of anthrax lethal toxin-induced cytolysis of RAW264.7 cells by celastrol.
PloS one 2008;3(1):e1421.
2007: Prakash Rai; Arundhati Saraph; Randolph Ashton; Vincent Poon; Jeremy Mogridge; Ravi S Kane
Raftlike polyvalent inhibitors of the anthrax toxin: modulating inhibitory potency by formation of lipid microdomains.
Angewandte Chemie (International ed. in English) 2007;46(13):2207-9.
2006: saleem basha; Prakash Rai; Vincent Poon; Arundhati Saraph; Kunal V Gujraty; Mandy Y Go; Skanda Sadacharan; Mia Frost; Jeremy Mogridge; Ravi S Kane
Polyvalent inhibitors of anthrax toxin that target host receptors.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(36):13509-13.
2006: Amit Joshi; Arundhati Saraph; Vincent Poon; Jeremy Mogridge; Ravi S Kane
Synthesis of potent inhibitors of anthrax toxin based on poly-L-glutamic acid.
Bioconjugate chemistry 2006;17(5):1265-9.
2006: Michael J Gubbins; Jody Berry; Cindi R Corbett; Jeremy Mogridge; Xin Y Yuan; Lisa Schmidt; Brigitte Nicolas; Amin Kabani; Raymond S W Tsang
Production and characterization of neutralizing monoclonal antibodies that recognize an epitope in domain 2 of Bacillus anthracis protective antigen.
FEMS immunology and medical microbiology 2006;47(3):436-43.
2006: Kunal V Gujraty; Amit Joshi; Arundhati Saraph; Vincent Poon; Jeremy Mogridge; Ravi S Kane
Synthesis of polyvalent inhibitors of controlled molecular weight: structure-activity relationship for inhibitors of anthrax toxin.
Biomacromolecules 2006;7(7):2082-5.
2006: Mandy Y Go; Sanguk Kim; Anthony W Partridge; Roman A Melnyk; Arianna Rath; Charles M Deber; Jeremy Mogridge
Self-association of the transmembrane domain of an anthrax toxin receptor.
Journal of molecular biology 2006;360(1):145-56.
2006: Prakash Rai; Chakradhar Padala; Vincent Poon; Arundhati Saraph; saleem basha; Sandesh Kate; Kevin Tao; Jeremy Mogridge; Ravi S Kane
Statistical pattern matching facilitates the design of polyvalent inhibitors of anthrax and cholera toxins.
Nature biotechnology 2006;24(5):582-6.
2006: Sarah Batty; Edith M C Chow; Altaf Kassam; Sandy D Der; Jeremy Mogridge
Inhibition of mitogen-activated protein kinase signalling by Bacillus anthracis lethal toxin causes destabilization of interleukin-8 mRNA.
Cellular microbiology 2006;8(1):130-8.
2005: Kunal V Gujraty; Skanda Sadacharan; Mia Frost; Vincent Poon; Ravi S Kane; Jeremy Mogridge
Functional characterization of peptide-based anthrax toxin inhibitors.
Molecular pharmaceutics 2005;2(5):367-72.
2005: Altaf Kassam; Sandy D Der; Jeremy Mogridge
Differentiation of human monocytic cell lines confers susceptibility to Bacillus anthracis lethal toxin.
Cellular microbiology 2005;7(2):281-92.
2004: Jeremy Mogridge
Anthrax and bioterrorism: are we prepared?
Lancet 2004;364(9432):393-5.
2004: Jeremy Mogridge
Using light scattering to determine the stoichiometry of protein complexes.
Methods in molecular biology (Clifton, N.J.) 2004;261():113-8.
2003: Kenneth A Bradley; Jeremy Mogridge; G Jonah; A Rainey; Sarah Batty; John A T Young
Binding of anthrax toxin to its receptor is similar to alpha integrin-ligand interactions.
The Journal of biological chemistry 2003;278(49):49342-7.
2002: Michael Mourez; D Borden Lacy; Kristina Cunningham; Rachel Legmann; Bret R Sellman; Jeremy Mogridge; R. John Collier
2001: a year of major advances in anthrax toxin research.
Trends in microbiology 2002;10(6):287-93.
2002: Kristina Cunningham; D Borden Lacy; Jeremy Mogridge; R. John Collier
Mapping the lethal factor and edema factor binding sites on oligomeric anthrax protective antigen.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):7049-53.
2002: Jeremy Mogridge; Kristina Cunningham; D Borden Lacy; Michael Mourez; R. John Collier
The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):7045-8.
2002: Jeremy Mogridge; Kristina Cunningham; R. John Collier
Stoichiometry of anthrax toxin complexes.
Biochemistry 2002;41(3):1079-82.
2001: Kenneth A Bradley; Jeremy Mogridge; Michael Mourez; R. John Collier; John A T Young
Identification of the cellular receptor for anthrax toxin.
Nature 2001;414(6860):225-9.
2001: Michael Mourez; Ravi S Kane; Jeremy Mogridge; Steven J Metallo; Pascal Deschatelets; Bret R Sellman; George M Whitesides; R. John Collier
Designing a polyvalent inhibitor of anthrax toxin.
Nature biotechnology 2001;19(10):958-61.
2001: Ying Zhou; Thien-Fah Mah; Y T Yu; Jeremy Mogridge; E R Olson; Jack Greenblatt; David I Friedman
Interactions of an Arg-rich region of transcription elongation protein NusA with NUT RNA: implications for the order of assembly of the lambda N antitermination complex in vivo.
Journal of molecular biology 2001;310(1):33-49.
2001: Jeremy Mogridge; Michael Mourez; R. John Collier
Involvement of domain 3 in oligomerization by the protective antigen moiety of anthrax toxin.
Journal of bacteriology 2001;183(6):2111-6.
2000: JL Elliott; Jeremy Mogridge; R. John Collier
A quantitative study of the interactions of Bacillus anthracis edema factor and lethal factor with activated protective antigen.
Biochemistry 2000;39(22):6706-13.
1998: Pascale Legault; Joyce Li; Jeremy Mogridge; Lewis E Kay; Jack Greenblatt
NMR structure of the bacteriophage lambda N peptide/boxB RNA complex: recognition of a GNRA fold by an arginine-rich motif.
Cell 1998;93(2):289-99.
1998: Jeremy Mogridge; Jack Greenblatt
Specific binding of Escherichia coli ribosomal protein S1 to boxA transcriptional antiterminator RNA.
Journal of bacteriology 1998;180(8):2248-52.
1998: Jeremy Mogridge; Thien-Fah Mah; Jack Greenblatt
Involvement of boxA nucleotides in the formation of a stable ribonucleoprotein complex containing the bacteriophage lambda N protein.
The Journal of biological chemistry 1998;273(7):4143-8.
1998: Jack Greenblatt; Thien-Fah Mah; Pascale Legault; Jeremy Mogridge; Joyce Li; Lewis E Kay
Structure and mechanism in transcriptional antitermination by the bacteriophage lambda N protein.
Cold Spring Harbor symposia on quantitative biology 1998;63():327-36.
1998: Jeremy Mogridge; Pascale Legault; Joyce Li; Mark Van Oene; Lewis E Kay; Jack Greenblatt
Independent ligand-induced folding of the RNA-binding domain and two functionally distinct antitermination regions in the phage lambda N protein.
Molecular cell 1998;1(2):265-75.
1995: Jeremy Mogridge; Thien-Fah Mah; Jack Greenblatt
A protein-RNA interaction network facilitates the template-independent cooperative assembly on RNA polymerase of a stable antitermination complex containing the lambda N protein.
Genes & development 1995;9(22):2831-45.
1994: Jim Hu; Y Xu; K Schappert; T Harrington; A Wang; R Braga; Jeremy Mogridge; James D Friesen
Mutational analysis of the PRP4 protein of Saccharomyces cerevisiae suggests domain structure and snRNP interactions.
Nucleic acids research 1994;22(9):1724-34.