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Kenneth Becker

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Kenneth L Becker
Immunoneutralization of procalcitonin or its component peptides: a promising treatment of sepsis.
Kenneth L Becker; Richard Snider; Eric S Nylen
Procalcitonin in sepsis and systemic inflammation: a harmful biomarker and a therapeutic target.
Kenneth L Becker; Richard H Snider; Eric S Nylen
Procalcitonin assay in systemic inflammation, infection, and sepsis: clinical utility and limitations.

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All Publications

2010: Kenneth L Becker
Immunoneutralization of procalcitonin or its component peptides: a promising treatment of sepsis.
Clinical science (London, England : 1979) 2010;119(12):515-7.
2010: Kenneth L Becker; Richard Snider; Eric S Nylen
Procalcitonin in sepsis and systemic inflammation: a harmful biomarker and a therapeutic target.
British journal of pharmacology 2010;159(2):253-64.
2008: Kenneth L Becker; Richard H Snider; Eric S Nylen
Procalcitonin assay in systemic inflammation, infection, and sepsis: clinical utility and limitations.
Critical care medicine 2008;36(3):941-52.
2005: Glenn R Stryjewski; Eric S Nylen; Michael J Bell; Richard H Snider; Kenneth L Becker; Amy Wu; Christopher Lawlor; Heidi J Dalton
Interleukin-6, interleukin-8, and a rapid and sensitive assay for calcitonin precursors for the determination of bacterial sepsis in febrile neutropenic children.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2005;6(2):129-35.
2004: Beat Müller; Mirjam Christ-Crain; Eric S Nylen; Richard H Snider; Kenneth L Becker
Limits to the use of the procalcitonin level as a diagnostic marker.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004;39(12):1867-8.
2004: Kenneth L Becker; Eric S Nylén; Jon C White; Beat Müller; Richard H Snider
Clinical review 167: Procalcitonin and the calcitonin gene family of peptides in inflammation, infection, and sepsis: a journey from calcitonin back to its precursors.
The Journal of clinical endocrinology and metabolism 2004;89(4):1512-25.
2003: Philippe Linscheid; Dalma Seboek; Eric S Nylen; Igor Langer; Mirjam Schlatter; Kenneth L Becker; Ulrich Keller; Beat Müller
In vitro and in vivo calcitonin I gene expression in parenchymal cells: a novel product of human adipose tissue.
Endocrinology 2003;144(12):5578-84.
2003: Basil J Ammori; Kenneth L Becker; Peter Kite; Richard H Snider; Eric S Nylén; Jon C White; GR Barclay; Michael Larvin; Michael John McMahon
Calcitonin precursors: early markers of gut barrier dysfunction in patients with acute pancreatitis.
Pancreas 2003;27(3):239-43.
2003: H Bihan; Kenneth L Becker; Richard H Snider; Eric S Nylen; L Vittaz; C Lauret; E Modigliani; J L Moretti; R Cohen
Calcitonin precursor levels in human medullary thyroid carcinoma.
Thyroid : official journal of the American Thyroid Association 2003;13(8):819-22.
2003: Eric S Nylen; Beat Muller; Kenneth L Becker; Richard H Snider
The future diagnostic role of procalcitonin levels: the need for improved sensitivity.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003;36(6):823-4; author reply 826-7.
2003: Basil J Ammori; Kenneth L Becker; Peter Kite; Richard H Snider; Eric S Nylén; Jon C White; Michael Larvin; Michael John McMahon
Calcitonin precursors in the prediction of severity of acute pancreatitis on the day of admission.
The British journal of surgery 2003;90(2):197-204.
2003: Kenneth L Becker; Eric S Nylén; Richard H Snider; Beat Müller; Jon C White
Immunoneutralization of procalcitonin as therapy of sepsis.
Journal of endotoxin research 2003;9(6):367-74.
2002: Kristin E Wagner; Jose Martinez; Steven D Vath; Richard H Snider; Eric S Nylén; Kenneth L Becker; Beat Müller; Jon C White
Early immunoneutralization of calcitonin precursors attenuates the adverse physiologic response to sepsis in pigs.
Critical care medicine 2002;30(10):2313-21.
2001: V S Domenech; Eric S Nylen; Jon C White; Richard H Snider; Kenneth L Becker; R Landmann; Beat Müller
Calcitonin gene-related peptide expression in sepsis: postulation of microbial infection-specific response elements within the calcitonin I gene promoter.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2001;49(6):514-21.
2001: HL Preas; Eric S Nylen; Richard H Snider; Kenneth L Becker; Jon C White; J M Agosti; Anthony F Suffredini
Effects of anti-inflammatory agents on serum levels of calcitonin precursors during human experimental endotoxemia.
The Journal of infectious diseases 2001;184(3):373-6.
2001: Gabriel I Uwaifo; A T Remaley; M Stene; James C Reynolds; Paul M Yen; Richard H Snider; Kenneth L Becker; Nicholas Sarlis
A case of spurious hypercalcitoninemia: a cautionary tale on the use of plasma calcitonin assays in the screening of patients with thyroid nodules for neoplasia.
Journal of endocrinological investigation 2001;24(5):361-9.
2001: Jose Martinez; K E Wagner; Richard H Snider; Eric S Nylen; Beat Muller; Babak Sarani; Kenneth L Becker; Jon C White
Late immunoneutralization of procalcitonin arrests the progression of lethal porcine sepsis.
Surgical infections 2001;2(3):193-202; discussion 202-3.
2001: Beat Müller; Jon C White; Eric S Nylén; Richard H Snider; Kenneth L Becker; Joel F Habener
Ubiquitous expression of the calcitonin-i gene in multiple tissues in response to sepsis.
The Journal of clinical endocrinology and metabolism 2001;86(1):396-404.
2000: Beat Müller; Kenneth L Becker; M Kränzlin; Hartmut Schächinger; Peter R Huber; E S Nylèn; Richard H Snider; Jon C White; H Schmidt-Gayk; Werner Zimmerli; R Ritz
Disordered calcium homeostasis of sepsis: association with calcitonin precursors.
European journal of clinical investigation 2000;30(9):823-31.
2000: KT Whang; Steven D Vath; Kenneth L Becker; Richard H Snider; Eric S Nylen; Beat Muller; Q Li; L Tamarkin; Jon C White
Procalcitonin and proinflammatory cytokine interactions in sepsis.
Shock (Augusta, Ga.) 2000;14(1):73-8.
2000: Beat Müller; Kenneth L Becker; Hartmut Schächinger; Peter Rickenbacher; Peter R Huber; Werner Zimmerli; R Ritz
Calcitonin precursors are reliable markers of sepsis in a medical intensive care unit.
Critical care medicine 2000;28(4):977-83.
1999: KT Whang; Steven D Vath; Kenneth L Becker; Richard H Snider; Eric S Nylen; Beat Muller; Q Li; L Tamarkin; Jon C White
Procalcitonin and proinflammatory cytokine in interactions in sepsis.
Shock (Augusta, Ga.) 1999;12(4):268-73.
1998: KT Whang; P M Steinwald; Jon C White; Eric S Nylen; Richard H Snider; G L Simon; R L Goldberg; Kenneth L Becker
Serum calcitonin precursors in sepsis and systemic inflammation.
The Journal of clinical endocrinology and metabolism 1998;83(9):3296-301.
1998: Eric S Nylen; KT Whang; Richard H Snider; P M Steinwald; Jon C White; Kenneth L Becker
Mortality is increased by procalcitonin and decreased by an antiserum reactive to procalcitonin in experimental sepsis.
Critical care medicine 1998;26(6):1001-6.
1997: Richard H Snider; Eric S Nylen; Kenneth L Becker
Procalcitonin and its component peptides in systemic inflammation: immunochemical characterization.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 1997;45(9):552-60.
1997: Eric S Nylén; A Al Arifi; Kenneth L Becker; Richard H Snider; Abdulaziz Alzeer
Effect of classic heatstroke on serum procalcitonin.
Critical care medicine 1997;25(8):1362-5.
1996: E S Nylén; Richard H Snider; K A Thompson; P Rohatgi; Kenneth L Becker
Pneumonitis-associated hyperprocalcitoninemia.
The American journal of the medical sciences 1996;312(1):12-8.
1995: Eric S Nylen; J Jeng; Marion H Jordan; Richard H Snider; K A Thompson; M S Lewis; W J O'Neill; Kenneth L Becker
Late pulmonary sequela following burns: persistence of hyperprocalcitonemia using a 1-57 amino acid N-terminal flanking peptide assay.
Respiratory medicine 1995;89(1):41-6.
1994: Eric S Nylen; J L Hall; S H Krasnow; Kenneth L Becker; Robert Wadleigh
Nonsurgical closure of esophago-respiratory fistulas: role for the somatostatin analogue octreotide acetate?
The American journal of the medical sciences 1994;308(3):152-6.
1994: M J Kelley; Richard H Snider; Kenneth L Becker; Bruce E Johnson
Small cell lung carcinoma cell lines express mRNA for calcitonin and alpha- and beta-calcitonin gene related peptides.
Cancer letters 1994;81(1):19-25.
1994: M J Kelley; Kenneth L Becker; J M Rushin; David Venzon; R Phelps; D C Ihde; D P Bliss; K Melby; Richard H Snider; Bruce E Johnson
Calcitonin elevation in small cell lung cancer without ectopic production.
American journal of respiratory and critical care medicine 1994;149(1):183-90.
1993: A R Tabassian; Richard H Snider; Eric S Nylen; M Cassidy; Kenneth L Becker
Heterogeneity studies of hamster calcitonin following acute exposure to cigarette smoke: evidence for monomeric secretion.
The Anatomical record 1993;236(1):253-6.
1993: Eric S Nylen; Kenneth L Becker
Chronic hyperoxia and hamster pulmonary neuroendocrine cell bombesin and calcitonin.
The Anatomical record 1993;236(1):248-52.
1993: J M Polak; Kenneth L Becker; E Cutz; D B Gail; Lucyna Goniakowska-Witalinska; J R Gosney; J M Lauweryns; I Linnoila; E M McDowell; Y E Miller
Lung endocrine cell markers, peptides, and amines.
The Anatomical record 1993;236(1):169-71.
1993: Kenneth L Becker; W J O'Neil; Richard H Snider; Eric S Nylen; C F Moore; J Jeng; O L Silva; M S Lewis; Marion H Jordan
Hypercalcitonemia in inhalation burn injury: a response of the pulmonary neuroendocrine cell?
The Anatomical record 1993;236(1):136-8, 172-3; discussion 138-43.
1993: Eric S Nylen; Kenneth L Becker; Richard H Snider; A R Tabassian; M M Cassidy; R I Linnoila
Cholinergic-nicotinic control of growth and secretion of cultured pulmonary neuroendocrine cells.
The Anatomical record 1993;236(1):129-35.
1992: W J O'Neill; Marion H Jordan; M S Lewis; Richard H Snider; C F Moore; Kenneth L Becker
Serum calcitonin may be a marker for inhalation injury in burns.
The Journal of burn care & rehabilitation 1992;13(6):605-16.
1992: Eric S Nylen; W O'Neill; Marion H Jordan; Richard H Snider; C F Moore; M Lewis; O L Silva; Kenneth L Becker
Serum procalcitonin as an index of inhalation injury in burns.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1992;24(9):439-43.
1990: A R Tabassian; Eric S Nylen; L Lukacs; M M Cassidy; Kenneth L Becker
Cholinergic regulation of hamster pulmonary neuroendocrine cell calcitonin.
Experimental lung research 1990;16(3):267-77.
1990: Hildegard M Schuller; H P Witschi; Eric S Nylen; P A Joshi; E Correa; Kenneth L Becker
Pathobiology of lung tumors induced in hamsters by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and the modulating effect of hyperoxia.
Cancer research 1990;50(6):1960-5.
1990: Eric S Nylen; Richard H Snider; C F Moore; Kenneth L Becker
Modulation of pulmonary bombesin by nicotine and vagotomy.
Life sciences 1990;47(3):213-8.
1990: Eric S Nylen; Kenneth L Becker; P A Joshi; Richard H Snider; Hildegard M Schuller
Pulmonary bombesin and calcitonin in hamsters during exposure to hyperoxia and diethylnitrosamine.
American journal of respiratory cell and molecular biology 1990;2(1):25-31.
1990: H M Schüller; Eric S Nylen; P Park; Kenneth L Becker
Nicotine, acetylcholine and bombesin are trophic growth factors in neuroendocrine cell lines derived from experimental hamster lung tumors.
Life sciences 1990;47(6):571-8.
1989: A R Tabassian; Eric S Nylen; R I Linnoila; Richard H Snider; M M Cassidy; Kenneth L Becker
Stimulation of hamster pulmonary neuroendocrine cells and associated peptides by repeated exposure to cigarette smoke.
The American review of respiratory disease 1989;140(2):436-40.
1988: L Y Korman; Eric S Nylen; T M Finan; R I Linnoila; Kenneth L Becker
Primary culture of the enteric nervous system from neonatal hamster intestine. Selection of vasoactive intestinal polypeptide-containing neurons.
Gastroenterology 1988;95(4):1003-10.
1988: Richard H Snider; C F Moore; Eric S Nylen; Kenneth L Becker
Improved HPLC separation of radiolabelled hormonal peptides.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1988;20(4):254-5.
1988: Hildegard M Schuller; Kenneth L Becker; H P Witschi
An animal model for neuroendocrine lung cancer.
Carcinogenesis 1988;9(2):293-6.
1988: A R Tabassian; Eric S Nylen; A E Giron; Richard H Snider; M M Cassidy; Kenneth L Becker
Evidence for cigarette smoke-induced calcitonin secretion from lungs of man and hamster.
Life sciences 1988;42(23):2323-9.
1988: E S Nylén; R I Linnoila; Kenneth L Becker
Prenatal cholinergic stimulation of pulmonary neuroendocrine cells by nicotine.
Acta physiologica Scandinavica 1988;132(1):117-8.
1987: Eric S Nylen; R I Linnoila; Richard H Snider; A R Tabassian; Kenneth L Becker
Comparative studies of hamster calcitonin from pulmonary endocrine cells in vitro.
Peptides 1987;8(6):977-82.
1986: A G Pedersen; Kenneth L Becker; F Bach; Richard H Snider; A F Gazdar; P S Sorensen; P A Bunn; Heine H Hansen
Cerebrospinal fluid bombesin and calcitonin in patients with central nervous system metastases from small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1986;4(11):1620-7.
1986: Bruce E Johnson; J Battey; I Linnoila; Kenneth L Becker; R W Makuch; Richard H Snider; D N Carney; J D Minna
Changes in the phenotype of human small cell lung cancer cell lines after transfection and expression of the c-myc proto-oncogene.
The Journal of clinical investigation 1986;78(2):525-32.
1984: R I Linnoila; Kenneth L Becker; O L Silva; Richard H Snider; C F Moore
Calcitonin as a marker for diethylnitrosamine-induced pulmonary endocrine cell hyperplasia in hamsters.
Laboratory investigation; a journal of technical methods and pathology 1984;51(1):39-45.
1983: Kenneth L Becker; A F Gazdar; D N Carney; Richard H Snider; C F Moore; O L Silva
Calcitonin secretion by continuous cultures of small cell carcinoma of the lung: incidence and immunoheterogeneity studies.
Cancer letters 1983;18(2):179-85.
1982: Kenneth L Becker; O L Silva; Richard H Snider; C F Moore; G W Geelhoed
The surgical implications of hypercalcitonemia.
Surgery, gynecology & obstetrics 1982;154(6):897-908.
1981: G W Geelhoed; Kenneth L Becker; W O'Neill; Richard H Snider; C F Moore; O L Silva
Calcitonin studies in the rhesus monkey.
World journal of surgery 1981;5(4):579-86.
1981: O L Silva; Kenneth L Becker; Richard H Snider; C F Moore; H M Lando
Urine calcitonin in normal children.
Pediatric research 1981;15(7):1032-5.
1981: Kenneth L Becker; O L Silva
Hypothesis: the bronchial Kulchitsky (K) cell as a source of humoral biologic activity.
Medical hypotheses 1981;7(7):943-9.
1981: Kenneth L Becker; D Nash; O L Silva; Richard H Snider; C F Moore
Increased serum and urinary calcitonin levels in patients with pulmonary disease.
Chest 1981;79(2):211-6.
1981: O L Silva; P Titus-Dillon; Kenneth L Becker; Richard H Snider; C F Moore
Increased serum calcitonin in pregnancy.
Journal of the National Medical Association 1981;73(7):649-52.
1980: Kenneth L Becker; O L Silva; J Cyrus; Richard H Snider; C F Moore
Hypercalcitonemia in pernicious anemia.
Experientia 1980;36(11):1330-1.
1980: Kenneth L Becker; O L Silva; R M Post; J C Ballenger; J S Carman; Richard H Snider; C F Moore
Immunoreactive calcitonin in cerebrospinal fluid of man.
Brain research 1980;194(2):598-602.
1980: Kenneth L Becker; O L Silva; L A Wisneski; J Cyrus; Richard H Snider; C F Moore; G A Higgins
Limited calcitonin reserve in hyperparathyroidism.
The American journal of the medical sciences 1980;280(1):11-5.
1980: Kenneth L Becker; G Geelhoed; W O'Neill; K G Monaghan; Richard H Snider; C F Moore; O L Silva
Calcitonin in tissues of thyroidectomized monkey.
Experientia 1980;36(5):609-10.
1980: Kenneth L Becker; K G Monaghan; O L Silva
Immunocytochemical localization of calcitonin in Kulchitsky cells of human lung.
Archives of pathology & laboratory medicine 1980;104(4):196-8.
1980: Kenneth L Becker; D R Nash; O L Silva; Richard H Snider; C F Moore
Urine calcitonin levels in patients with bronchogenic carcinoma.
JAMA : the journal of the American Medical Association 1980;243(7):670-2.