Subburaman Mohan

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Chemicals & Drugs

Anatomy

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Bone Density

Physiology

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Publications

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Hall Susan L; Chen Shin-Tai; Gysin Reinhard; Gridley Daila S; Mohan Subburaman; Lau K-H William
Stem cell antigen-1+ cell-based bone morphogenetic protein-4 gene transfer strategy in mice failed to promote endosteal bone formation.
Ohlsson Claes; Mohan Subburaman; Sjögren Klara; Tivesten Asa; Isgaard Jörgen; Isaksson Olle; Jansson John-Olov; Svensson Johan
The role of liver-derived insulin-like growth factor-I.
Sjögren Klara; Lagerquist Marie; Moverare-Skrtic Sofia; Andersson Niklas; Windahl Sara H; Swanson Charlotte; Mohan Subburaman; Poutanen Matti; Ohlsson Claes
Elevated aromatase expression in osteoblasts leads to increased bone mass without systemic adverse effects.

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All Publications

2009: Hall Susan L; Chen Shin-Tai; Gysin Reinhard; Gridley Daila S; Mohan Subburaman; Lau K-H William
Stem cell antigen-1+ cell-based bone morphogenetic protein-4 gene transfer strategy in mice failed to promote endosteal bone formation.
The journal of gene medicine 2009;11(10):877-88.
2009: Ohlsson Claes; Mohan Subburaman; Sjögren Klara; Tivesten Asa; Isgaard Jörgen; Isaksson Olle; Jansson John-Olov; Svensson Johan
The role of liver-derived insulin-like growth factor-I.
Endocrine reviews 2009;30(5):494-535.
2009: Sjögren Klara; Lagerquist Marie; Moverare-Skrtic Sofia; Andersson Niklas; Windahl Sara H; Swanson Charlotte; Mohan Subburaman; Poutanen Matti; Ohlsson Claes
Elevated aromatase expression in osteoblasts leads to increased bone mass without systemic adverse effects.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009;24(7):1263-70.
2009: Linares Gabriel R; Xing Weirong; Govoni Kristen E; Chen Shin-Tai; Mohan Subburaman
Glutaredoxin 5 regulates osteoblast apoptosis by protecting against oxidative stress.
Bone 2009;44(5):795-804.
2009: Govoni K E; Linares G R; Chen S-T; Pourteymoor S; Mohan S
T-box 3 negatively regulates osteoblast differentiation by inhibiting expression of osterix and runx2.
Journal of cellular biochemistry 2009;106(3):482-90.
2009: Yu Hongrun; Edderkaoui Bouchra; Cortez Alejandro; Davidson Heather M; Wergedal Jon E; Baylink David J; Mohan Subburaman
Mapping of the chromosome 17 BMD QTL in the F(2) male mice of MRL/MpJ x SJL/J.
Genetica 2009;135(1):59-66.
2008: Govoni Kristen E; Wergedal Jon E; Chadwick Robert B; Srivastava Apurva K; Mohan Subburaman
Prepubertal OVX increases IGF-I expression and bone accretion in C57BL/6J mice.
American journal of physiology. Endocrinology and metabolism 2008;295(5):E1172-80.
2008: Rundle Charles H; Wang Xiaoguang; Sheng Matilda H-C; Wergedal Jon E; Lau K-H William; Mohan Subburaman
Bax deficiency in mice increases cartilage production during fracture repair through a mechanism involving increased chondrocyte proliferation without changes in apoptosis.
Bone 2008;43(5):880-8.
2008: Rundle Charles H; Wang Xiaoguang; Wergedal Jon E; Mohan Subburaman; Lau K-H William
Fracture healing in mice deficient in plasminogen activator inhibitor-1.
Calcified tissue international 2008;83(4):276-84.
2008: Strohbach Cassandra; Kleinman Sabrina; Linkhart Thomas; Amaar Yousef; Chen Shin-Tai; Mohan Subburaman; Strong Donna
Potential involvement of the interaction between insulin-like growth factor binding protein (IGFBP)-6 and LIM mineralization protein (LMP)-1 in regulating osteoblast differentiation.
Journal of cellular biochemistry 2008;104(5):1890-905.
2008: Sheng Matilda H-C; Wergedal Jon E; Mohan Subburaman; Lau K-H William
Osteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity.
FEBS letters 2008;582(10):1451-8.
2008: Mohan Subburaman; Baylink David J; Srivastava Apurva K
A chemical mutagenesis screen to identify modifier genes that interact with growth hormone and TGF-beta signaling pathways.
Bone 2008;42(2):388-95.
2008: Kesavan Chandrasekhar; Mohan Subburaman
Lack of anabolic response to skeletal loading in mice with targeted disruption of the pleiotrophin gene.
BMC research notes 2008;1():124.
2007: Chen Andy B; Hamamura Kazunori; Wang Guohua; Xing Weirong; Mohan Subburaman; Yokota Hiroki; Liu Yunlong
Model-based comparative prediction of transcription-factor binding motifs in anabolic responses in bone.
Genomics, proteomics & bioinformatics / Beijing Genomics Institute 2007;5(3-4):158-65.
2007: Rehage Mark; Mohan Subburaman; Wergedal Jon E; Bonafede Blake; Tran Kiet; Hou Diana; Phang David; Kumar Ashok; Qin Xuezhong
Transgenic overexpression of pregnancy-associated plasma protein-A increases the somatic growth and skeletal muscle mass in mice.
Endocrinology 2007;148(12):6176-85.
2007: Govoni Kristen E; Wergedal Jon E; Florin Lore; Angel Peter; Baylink David J; Mohan Subburaman
Conditional deletion of insulin-like growth factor-I in collagen type 1alpha2-expressing cells results in postnatal lethality and a dramatic reduction in bone accretion.
Endocrinology 2007;148(12):5706-15.
2007: Yu Hongrun; Baylink David J; Masinde Godfred L; Li Runzhi; Nguyen Bay; Davidson Heather M; Xu Shizhong; Mohan Subburaman
Mouse chromosome 9 quantitative trait loci for soft tissue regeneration: congenic analysis and fine mapping.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2007;15(6):922-7.
2007: Hall Susan L; Lau Kin-Hing William; Chen Shin-Tai; Wergedal Jon E; Srivastava Apurva; Klamut Henry; Sheng Matilda H-C; Gridley Daila S; Mohan Subburaman; Baylink David J
Sca-1(+) hematopoietic cell-based gene therapy with a modified FGF-2 increased endosteal/trabecular bone formation in mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(10):1881-9.
2007: Edderkaoui B; Baylink D J; Beamer W G; Shultz K L; Wergedal J E; Mohan S
Genetic regulation of femoral bone mineral density: complexity of sex effect in chromosome 1 revealed by congenic sublines of mice.
Bone 2007;41(3):340-5.
2007: Kesavan Chandrasekhar; Baylink David J; Kapoor Susanna; Mohan Subburaman
Novel loci regulating bone anabolic response to loading: expression QTL analysis in C57BL/6JXC3H/HeJ mice cross.
Bone 2007;41(2):223-30.
2007: Govoni Kristen E; Lee Seong Keun; Chung Yoon-Sok; Behringer Richard R; Wergedal Jon E; Baylink David J; Mohan Subburaman
Disruption of insulin-like growth factor-I expression in type IIalphaI collagen-expressing cells reduces bone length and width in mice.
Physiological genomics 2007;30(3):354-62.
2007: Wergedal Jon E; Ackert-Bicknell Cheryl L; Beamer Wesley G; Mohan Subburaman; Baylink David J; Srivastava Apurva K
Mapping genetic loci that regulate lipid levels in a NZB/B1NJxRF/J intercross and a combined intercross involving NZB/B1NJ, RF/J, MRL/MpJ, and SJL/J mouse strains.
Journal of lipid research 2007;48(8):1724-34.
2007: Xing Weirong; Singgih Anny; Kapoor Anil; Alarcon Catrina M; Baylink David J; Mohan Subburaman
Nuclear factor-E2-related factor-1 mediates ascorbic acid induction of osterix expression via interaction with antioxidant-responsive element in bone cells.
The Journal of biological chemistry 2007;282(30):22052-61.
2007: Svensson Johan; Tivesten Asa; Sjögren Klara; Isaksson Olle; Bergström Göran; Mohan Subburaman; Mölne Johan; Isgaard Jörgen; Ohlsson Claes
Liver-derived IGF-I regulates kidney size, sodium reabsorption, and renal IGF-II expression.
The Journal of endocrinology 2007;193(3):359-66.
2007: Wang Xiaoguang; Rundle Charles H; Wergedal Jon E; Srivastava Apurva K; Mohan Subburaman; Lau K-H William
Loss of sex-specific difference in femoral bone parameters in male leptin knockout mice.
Calcified tissue international 2007;80(6):374-82.
2007: Ehrnborg Christer; Ohlsson Claes; Mohan Subburaman; Bengtsson Bengt-Ake; Rosén Thord
Increased serum concentration of IGFBP-4 and IGFBP-5 in healthy adults during one month's treatment with supraphysiological doses of growth hormone.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2007;17(3):234-41.
2007: Edderkaoui Bouchra; Baylink David J; Beamer Wesley G; Wergedal Jon E; Porte Ryan; Chaudhuri Asok; Mohan Subburaman
Identification of mouse Duffy antigen receptor for chemokines (Darc) as a BMD QTL gene.
Genome research 2007;17(5):577-85.
2007: Gheorghe Ciprian P; Mohan Subburaman; Oberg Kerby C; Longo Lawrence D
Gene expression patterns in the hypoxic murine placenta: a role in epigenesis?
Reproductive sciences (Thousand Oaks, Calif.) 2007;14(3):223-33.
2007: Chadwick Robert B; Bu Liming; Yu Hongrun; Hu Yan; Wergedal Jon E; Mohan Subburaman; Baylink David J
Digit tip regrowth and differential gene expression in MRL/Mpj, DBA/2, and C57BL/6 mice.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2007;15(2):275-84.
2007: Kasukawa Yuji; Miyakoshi Naohisa; Srivastava Apurva K; Nozaka Koji; Maekawa Shigeto; Baylink David J; Mohan Subburaman; Itoi Eiji
The selective cyclooxygenase-2 inhibitor celecoxib reduces bone resorption, but not bone formation, in ovariectomized mice in vivo.
The Tohoku journal of experimental medicine 2007;211(3):275-83.
2007: Yu H; Mohan S; Edderkaoui B; Masinde G L; Davidson H M; Wergedal J E; Beamer W G; Baylink D J
Detecting novel bone density and bone size quantitative trait loci using a cross of MRL/MpJ and CAST/EiJ inbred mice.
Calcified tissue international 2007;80(2):103-10.
2006: Qin Xuezhong; Wergedal Jon E; Rehage Mark; Tran Kiet; Newton Jacqueline; Lam Paggie; Baylink David J; Mohan Subburaman
Pregnancy-associated plasma protein-A increases osteoblast proliferation in vitro and bone formation in vivo.
Endocrinology 2006;147(12):5653-61.
2006: Amaar Yousef G; Minera Marlon G; Hatran Laurice K; Strong Donna D; Mohan Subburaman; Reeves Mark E
Ras association domain family 1C protein stimulates human lung cancer cell proliferation.
American journal of physiology. Lung cellular and molecular physiology 2006;291(6):L1185-90.
2006: Xing Weirong; Baylink David; Kapoor Anil; Mohan Subburaman
A platform of high-efficiency nonviral gene transfer in mouse osteoblast cells in vitro.
Molecular biotechnology 2006;34(1):29-35.
2006: Kesavan Chandrasekhar; Mohan Subburaman; Srivastava Apurva K; Kapoor Susanna; Wergedal Jon E; Yu Hongrun; Baylink David J
Identification of genetic loci that regulate bone adaptive response to mechanical loading in C57BL/6J and C3H/HeJ mice intercross.
Bone 2006;39(3):634-43.
2006: Govoni Kristen E; Lee Seong Keun; Chadwick Robert B; Yu Hongrun; Kasukawa Yuji; Baylink David J; Mohan Subburaman
Whole genome microarray analysis of growth hormone-induced gene expression in bone: T-box3, a novel transcription factor, regulates osteoblast proliferation.
American journal of physiology. Endocrinology and metabolism 2006;291(1):E128-36.
2006: Gheorghe Ciprian; Mohan Subburaman; Longo Lawrence D
Gene expression patterns in the developing murine placenta.
Journal of the Society for Gynecologic Investigation 2006;13(4):256-62.
2006: Sheng M H-C; Lau K-H W; Mohan S; Baylink D J; Wergedal J E
High osteoblastic activity in C3H/HeJ mice compared to C57BL/6J mice is associated with low apoptosis in C3H/HeJ osteoblasts.
Calcified tissue international 2006;78(5):293-301.
2006: Dogra Charu; Changotra Harish; Mohan Subburaman; Kumar Ashok
Tumor necrosis factor-like weak inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor-kappaB and degradation of MyoD protein.
The Journal of biological chemistry 2006;281(15):10327-36.
2006: Rundle Charles H; Wang Hali; Yu Hongrun; Chadwick Robert B; Davis Emile I; Wergedal Jon E; Lau K-H William; Mohan Subburaman; Ryaby James T; Baylink David J
Microarray analysis of gene expression during the inflammation and endochondral bone formation stages of rat femur fracture repair.
Bone 2006;38(4):521-9.
2006: Masinde Godfred L; Li Runzhi; Nguyen Bay; Yu Hongrun; Srivastava Apurva K; Edderkaoui Bouchra; Wergedal Jon E; Baylink David J; Mohan Subburaman
New quantitative trait loci that regulate wound healing in an intercross progeny from DBA/1J and 129 x 1/SvJ inbred strains of mice.
Functional & integrative genomics 2006;6(2):157-63.
2006: Amaar Yousef G; Tapia Blanca; Chen Shin-Tai; Baylink David J; Mohan Subburaman
Identification and characterization of novel IGFBP5 interacting protein: evidence IGFBP5-IP is a potential regulator of osteoblast cell proliferation.
American journal of physiology. Cell physiology 2006;290(3):C900-6.
2006: Edderkaoui Bouchra; Baylink David J; Beamer Wesley G; Wergedal Jon E; Dunn Nancy R; Shultz Kathryn L; Mohan Subburaman
Multiple genetic loci from CAST/EiJ chromosome 1 affect vBMD either positively or negatively in a C57BL/6J background.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21(1):97-104.
2006: Srivastava Apurva K; Mohan Subburaman; Masinde Godfred L; Yu Hongrun; Baylink David J
Identification of quantitative trait loci that regulate obesity and serum lipid levels in MRL/MpJ x SJL/J inbred mice.
Journal of lipid research 2006;47(1):123-33.
2005: Yu Hongrun; Mohan Subburaman; Masinde Godfred L; Baylink David J
Mapping the dominant wound healing and soft tissue regeneration QTL in MRL x CAST.
Mammalian genome : official journal of the International Mammalian Genome Society 2005;16(12):918-24.
2005: Wedhas Nia; Klamut Henry J; Dogra Charu; Srivastava Apurva K; Mohan Subburaman; Kumar Ashok
Inhibition of mechanosensitive cation channels inhibits myogenic differentiation by suppressing the expression of myogenic regulatory factors and caspase-3 activity.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(14):1986-97.
2005: Xing Weirong; Baylink David; Kesavan Chandrasekhar; Hu Yan; Kapoor Susanna; Chadwick Robert B; Mohan Subburaman
Global gene expression analysis in the bones reveals involvement of several novel genes and pathways in mediating an anabolic response of mechanical loading in mice.
Journal of cellular biochemistry 2005;96(5):1049-60.
2005: Kumar Ashok; Mohan Subburaman; Newton Jacqueline; Rehage Mark; Tran Kiet; Baylink David J; Qin Xuezhong
Pregnancy-associated plasma protein-A regulates myoblast proliferation and differentiation through an insulin-like growth factor-dependent mechanism.
The Journal of biological chemistry 2005;280(45):37782-9.
2005: Kesavan Chandrasekhar; Mohan Subburaman; Oberholtzer Susanna; Wergedal Jon E; Baylink David J
Mechanical loading-induced gene expression and BMD changes are different in two inbred mouse strains.
Journal of applied physiology (Bethesda, Md. : 1985) 2005;99(5):1951-7.
2005: Mohan Subburaman; Kapoor Anil; Singgih Anny; Zhang Zhang; Taylor Tim; Yu Hongrun; Chadwick Robert B; Chung Yoon-Sok; Donahue Leah Rae; Rosen Clifford; Crawford Grace C; Wergedal Jon; Baylink David J
Spontaneous fractures in the mouse mutant sfx are caused by deletion of the gulonolactone oxidase gene, causing vitamin C deficiency.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005;20(9):1597-610.
2005: Amaar Yousef G; Baylink David J; Mohan Subburaman
Ras-association domain family 1 protein, RASSF1C, is an IGFBP-5 binding partner and a potential regulator of osteoblast cell proliferation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005;20(8):1430-9.
2005: Andersson Martin K; Stark André; Anissian Lucas; Mohan Subburaman; Tsai Jon A
Low IGF-I in synovial fluid and serum in patients with aseptic prosthesis loosening.
Acta orthopaedica 2005;76(3):320-5.
2005: Wang Hui; Zhang Yuan-Ming; Li Xinmin; Masinde Godfred L; Mohan Subburaman; Baylink David J; Xu Shizhong
Bayesian shrinkage estimation of quantitative trait loci parameters.
Genetics 2005;170(1):465-80.
2005: Kapur Sonia; Mohan Subburaman; Baylink David J; Lau K-H William
Fluid shear stress synergizes with insulin-like growth factor-I (IGF-I) on osteoblast proliferation through integrin-dependent activation of IGF-I mitogenic signaling pathway.
The Journal of biological chemistry 2005;280(20):20163-70.
2005: Rooman Raoul P A; De Beeck Lieve Op; Martin Manou; van Doorn Jaap; Mohan Subburaman; Du Caju Marc V L
Ethinylestradiol and testosterone have divergent effects on circulating IGF system components in adolescents with constitutional tall stature.
European journal of endocrinology / European Federation of Endocrine Societies 2005;152(4):597-604.
2005: Masinde Godfred; Li Xinmin; Baylink David J; Nguyen Bay; Mohan Subburaman
Isolation of wound healing/regeneration genes using restrictive fragment differential display-PCR in MRL/MPJ and C57BL/6 mice.
Biochemical and biophysical research communications 2005;330(1):117-22.
2005: Govoni Kristen E; Baylink David J; Mohan Subburaman
The multi-functional role of insulin-like growth factor binding proteins in bone.
Pediatric nephrology (Berlin, Germany) 2005;20(3):261-8.
2005: Lorentzon Mattias; Greenhalgh Chris J; Mohan Subburaman; Alexander Warren S; Ohlsson Claes
Reduced bone mineral density in SOCS-2-deficient mice.
Pediatric research 2005;57(2):223-6.
2005: Salih Dervis A M; Mohan Subburaman; Kasukawa Yuji; Tripathi Gyanendra; Lovett Fiona A; Anderson Neil F; Carter Emma J; Wergedal Jon E; Baylink David J; Pell Jennifer M
Insulin-like growth factor-binding protein-5 induces a gender-related decrease in bone mineral density in transgenic mice.
Endocrinology 2005;146(2):931-40.
2005: Fleenor Donald; Oden Jon; Kelly Paul A; Mohan Subburaman; Alliouachene Samira; Pende Mario; Wentz Sabrina; Kerr Jennifer; Freemark Michael
Roles of the lactogens and somatogens in perinatal and postnatal metabolism and growth: studies of a novel mouse model combining lactogen resistance and growth hormone deficiency.
Endocrinology 2005;146(1):103-12.
2004: Fischer Frank; Schulte Helmut; Mohan Subburaman; Tataru Mira-Christine; Köhler Ekkehart; Assmann Gerd; von Eckardstein Arnold
Associations of insulin-like growth factors, insulin-like growth factor binding proteins and acid-labile subunit with coronary heart disease.
Clinical endocrinology 2004;61(5):595-602.
2004: Faridi Jesika S; Mohan Subburaman; De León Daisy D
Modulation of cathepsin D routing by IGF-II involves IGF-II binding to IGF-II/M6P receptor in MCF-7 breast cancer cells.
Growth factors (Chur, Switzerland) 2004;22(3):169-77.
2004: Chung Yoon-Sok; Baylink David J; Srivastava Apurva K; Amaar Yousef; Tapia Blanca; Kasukawa Yuji; Mohan Subburaman
Effects of secreted frizzled-related protein 3 on osteoblasts in vitro.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(9):1395-402.
2004: Xing Weirong; Baylink David; Kesavan Chandrasekhar; Mohan Subburaman
HSV-1 amplicon-mediated transfer of 128-kb BMP-2 genomic locus stimulates osteoblast differentiation in vitro.
Biochemical and biophysical research communications 2004;319(3):781-6.
2004: Bowers Cyril Y; Granda Ramona; Mohan Subburaman; Kuipers Jonathan; Baylink David; Veldhuis Johannes D
Sustained elevation of pulsatile growth hormone (GH) secretion and insulin-like growth factor I (IGF-I), IGF-binding protein-3 (IGFBP-3), and IGFBP-5 concentrations during 30-day continuous subcutaneous infusion of GH-releasing peptide-2 in older men and women.
The Journal of clinical endocrinology and metabolism 2004;89(5):2290-300.
2004: Eckstein Felix; Weusten Axel; Schmidt Corina; Wehr Ulrich; Wanke Rüdiger; Rambeck Walter; Wolf Eckhard; Mohan Subburaman
Longitudinal in vivo effects of growth hormone overexpression on bone in transgenic mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(5):802-10.
2004: Mazerbourg Sabine; Callebaut Isabelle; Zapf Jürgen; Mohan Subburaman; Overgaard Michael; Monget Philippe
Up date on IGFBP-4: regulation of IGFBP-4 levels and functions, in vitro and in vivo.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2004;14(2):71-84.
2004: Sivanandam Arun S; Mohan Subburaman; Kita Hirohito; Kapur Sanjay; Chen Shin-Tai; Linkhart Thomas A; Bagi Gyorgy; Baylink David J; Qin Xuezhong
Studies on regulation of IGF (insulin-like growth factor)-binding protein (IGFBP) 4 proteolysis by pregnancy-associated plasma protein-A (PAPP-A) in cells treated with phorbol ester.
The Biochemical journal 2004;379(Pt 1):57-64.
2004: Sivanandam Arun S; Mohan Subburaman; Kapur Sanjay; Kita Hirohito; Lau K-H William; Bagi Gyorgy; Baylink David J; Qin Xuezhong
Covalent interaction between proform of eosinophil major basic protein (proMBP) and pregnancy-associated plasma protein-A (PAPP-A) is a cell-mediated event and required for proMBP inhibition of the catalytic activity of PAPP-A.
Archives of biochemistry and biophysics 2004;423(2):343-50.
2004: Kasukawa Yuji; Miyakoshi Naohisa; Mohan Subburaman
The anabolic effects of GH/IGF system on bone.
Current pharmaceutical design 2004;10(21):2577-92.
2004: Fiedler Roman; Deuber Heinz J; Langer Thomas; Osten Bernd; Mohan Subburaman; Jehle Peter M
Effects of reduced dialysate calcium on calcium-phosphorus product and bone metabolism in hemodialysis patients.
Nephron. Clinical practice 2004;96(1):c3-9.
2003: Movérare Sofia; Venken Katrien; Eriksson Anna-Lena; Andersson Niklas; Skrtic Stanko; Wergedal Jon; Mohan Subburaman; Salmon Phil; Bouillon Roger; Gustafsson Jan-Ake; Vanderschueren Dirk; Ohlsson Claes
Differential effects on bone of estrogen receptor alpha and androgen receptor activation in orchidectomized adult male mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(23):13573-8.
2003: Kasukawa Yuji; Baylink David J; Wergedal Jon E; Amaar Yousef; Srivastava Apurva K; Guo Rongqing; Mohan Subburaman
Lack of insulin-like growth factor I exaggerates the effect of calcium deficiency on bone accretion in mice.
Endocrinology 2003;144(11):4682-9.
2003: Donahue Leah Rae; Chang Bo; Mohan Subburaman; Miyakoshi Nao; Wergedal Jon E; Baylink David J; Hawes Norman L; Rosen Clifford J; Ward-Bailey Patricia; Zheng Qing Y; Bronson Roderick T; Johnson Kenneth R; Davisson Muriel T
A missense mutation in the mouse Col2a1 gene causes spondyloepiphyseal dysplasia congenita, hearing loss, and retinoschisis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(9):1612-21.
2003: Kasukawa Yuji; Baylink David J; Guo Rongqing; Mohan Subburaman
Evidence that sensitivity to growth hormone (GH) is growth period and tissue type dependent: studies in GH-deficient lit/lit mice.
Endocrinology 2003;144(9):3950-7.
2003: Srivastava A K; Mohan S; Wergedal J E; Baylink D J
A genomewide screening of N-ethyl-N-nitrosourea-mutagenized mice for musculoskeletal phenotypes.
Bone 2003;33(2):179-91.
2003: Mohan Subburaman; Masinde Godfred; Li Xinmin; Baylink David J
Mapping quantitative trait loci that influence serum insulin-like growth factor binding protein-5 levels in F2 mice (MRL/MpJ X SJL/J).
Endocrinology 2003;144(8):3491-6.
2003: Masinde G L; Wergedal J; Davidson H; Mohan S; Li R; Li X; Baylink D J
Quantitative trait loci for periosteal circumference (PC): identification of single loci and epistatic effects in F2 MRL/SJL mice.
Bone 2003;32(5):554-60.
2003: Mohan Subburaman; Richman Charmaine; Guo Rongqing; Amaar Yousef; Donahue Leah Rea; Wergedal Jon; Baylink David J
Insulin-like growth factor regulates peak bone mineral density in mice by both growth hormone-dependent and -independent mechanisms.
Endocrinology 2003;144(3):929-36.
2002: Mohan Subburaman; Thompson Garrett R; Amaar Yousef G; Hathaway Gary; Tschesche Harald; Baylink David J
ADAM-9 is an insulin-like growth factor binding protein-5 protease produced and secreted by human osteoblasts.
Biochemistry 2002;41(51):15394-403.
2002: Sjögren Klara; Sheng Matilda; Movérare Sofia; Liu Jun-Li; Wallenius Kristina; Törnell Jan; Isaksson Olle; Jansson John-Olov; Mohan Subburaman; Ohlsson Claes
Effects of liver-derived insulin-like growth factor I on bone metabolism in mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(11):1977-87.
2002: Masinde G L; Li X; Gu W; Wergedal J; Mohan S; Baylink D J
Quantitative trait loci for bone density in mice: the genes determining total skeletal density and femur density show little overlap in F2 mice.
Calcified tissue international 2002;71(5):421-8.
2002: Li X; Srivastava A K; Gu W; Masinde G; Mohan S; Baylink D J
Opposing changes in osteocalcin levels in bone vs serum during the acquisition of peak bone density in C3H/HeJ and C57BL/6J mice.
Calcified tissue international 2002;71(5):416-20.
2002: Mohan S; Baylink D J
IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms.
The Journal of endocrinology 2002;175(1):19-31.
2002: Qin Xuezhong; Sexton Christopher; Byun Dongwon; Strong Donna D; Baylink David J; Mohan Subburaman
Differential regulation of pregnancy associated plasma protein (PAPP)-A during pregnancy in human and mouse.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2002;12(5):359-66.
2002: Sugimoto Toshitsugu; Kaji Hiroshi; Nakaoka Daiki; Yamauchi Mika; Yano Shozo; Sugishita Takeshi; Baylink David J; Mohan Subburaman; Chihara Kazuo
Effect of low-dose of recombinant human growth hormone on bone metabolism in elderly women with osteoporosis.
European journal of endocrinology / European Federation of Endocrine Societies 2002;147(3):339-48.
2002: Kasukawa Yuji; Stabnov Lisa; Miyakoshi Naohisa; Baylink David J; Mohan Subburaman
Insulin-like growth factor I effect on the number of osteoblast progenitors is impaired in ovariectomized mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(9):1579-87.
2002: Masinde Godfred L; Li Xinmin; Gu Weikuan; Hamilton-Ulland Melanie; Mohan Subburaman; Baylink David J
Quantitative trait loci that harbor genes regulating muscle size in (MRL/MPJ x SJL/J) F(2) mice.
Functional & integrative genomics 2002;2(3):120-5.
2002: Masinde Godfred L; Li Xinmin; Gu Weikuan; Davidson Heather; Hamilton-Ulland Melanie; Wergedal Jon; Mohan Subburaman; Baylink David J
Quantitative trait loci (QTL) for lean body mass and body length in MRL/MPJ and SJL/J F(2) mice.
Functional & integrative genomics 2002;2(3):98-104.
2002: Gysin R; Wergedal J E; Sheng M H-C; Kasukawa Y; Miyakoshi N; Chen S-T; Peng H; Lau K-H W; Mohan S; Baylink D J
Ex vivo gene therapy with stromal cells transduced with a retroviral vector containing the BMP4 gene completely heals critical size calvarial defect in rats.
Gene therapy 2002;9(15):991-9.
2002: Srivastava A K; Mohan S; Singer F R; Baylink D J
A urine midmolecule osteocalcin assay shows higher discriminatory power than a serum midmolecule osteocalcin assay during short-term alendronate treatment of osteoporotic patients.
Bone 2002;31(1):62-9.
2002: Stabnov L; Kasukawa Y; Guo R; Amaar Y; Wergedal J E; Baylink D J; Mohan S
Effect of insulin-like growth factor-1 (IGF-1) plus alendronate on bone density during puberty in IGF-1-deficient MIDI mice.
Bone 2002;30(6):909-16.
2002: Rooman Raoul P A; De Beeck Lieve Op; Martin Manou; Van Doorn Jaap; Mohan Subburaman; Du Caju Marc V L
IGF-I, IGF-II, 'free' IGF-I and IGF-binding proteins-2 to -6 during high-dose oestrogen treatment in constitutionally tall girls.
European journal of endocrinology / European Federation of Endocrine Societies 2002;146(6):823-9.
2002: Li Xinmin; Masinde Godfred; Gu Weikuan; Wergedal Jon; Mohan Subburaman; Baylink David J
Genetic dissection of femur breaking strength in a large population (MRL/MpJ x SJL/J) of F2 Mice: single QTL effects, epistasis, and pleiotropy.
Genomics 2002;79(5):734-40.
2002: Gu Weikuan; Li Xinmin; Lau K-H William; Edderkaoui Bouchra; Donahae Leah R; Rosen Clifford J; Beamer Wesley G; Shultz Kathryn L; Srivastava Apurva; Mohan Subburaman; Baylink David J
Gene expression between a congenic strain that contains a quantitative trait locus of high bone density from CAST/EiJ and its wild-type strain C57BL/6J.
Functional & integrative genomics 2002;1(6):375-86.
2002: Li Xinmin; Masinde Godfred; Gu Weikuan; Wergedal Jon; Hamilton-Ulland Melanie; Xu Shizhong; Mohan Subburaman; Baylink David J
Chromosomal regions harboring genes for the work to femur failure in mice.
Functional & integrative genomics 2002;1(6):367-74.
2002: Cheng Ming Zhao; Rawlinson Simon C F; Pitsillides Andrew A; Zaman Gul; Mohan Subburaman; Baylink David J; Lanyon Lance E
Human osteoblasts' proliferative responses to strain and 17beta-estradiol are mediated by the estrogen receptor and the receptor for insulin-like growth factor I.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(4):593-602.
2002: Lindberg Marie K; Movérare Sofia; Skrtic Stanko; Alatalo Sari; Halleen Jussi; Mohan Subburaman; Gustafsson J A; Ohlsson Claes
Two different pathways for the maintenance of trabecular bone in adult male mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(4):555-62.
2002: Amaar Yousef G; Thompson Garrett R; Linkhart Thomas A; Chen Shin-Tai; Baylink David J; Mohan Subburaman
Insulin-like growth factor-binding protein 5 (IGFBP-5) interacts with a four and a half LIM protein 2 (FHL2).
The Journal of biological chemistry 2002;277(14):12053-60.
2002: Li Xinmin; Gu Weikuan; Mohan Subburaman; Baylink David J
DNA microarrays: their use and misuse.
Microcirculation (New York, N.Y. : 1994) 2002;9(1):13-22.
2002: Umemura Yoshihisa; Baylink David J; Wergedal Jon E; Mohan Subburaman; Srivastava Apurva K
A time course of bone response to jump exercise in C57BL/6J mice.
Journal of bone and mineral metabolism 2002;20(4):209-15.
2002: Gu W K; Li X M; Edderkaoui B; Strong D D; Lau K H W; Beamer W G; Donahue L R; Mohan S; Baylink D J
Construction of a BAC contig for a 3 cM biologically significant region of mouse chromosome 1.
Genetica 2002;114(1):1-9.
2001: Srivastava A K; MacFarlane G; Srivastava V P; Mohan S; Baylink D J
A new monoclonal antibody ELISA for detection and characterization of C-telopeptide fragments of type I collagen in urine.
Calcified tissue international 2001;69(6):327-36.
2001: Masinde G L; Li X; Gu W; Davidson H; Mohan S; Baylink D J
Identification of wound healing/regeneration quantitative trait loci (QTL) at multiple time points that explain seventy percent of variance in (MRL/MpJ and SJL/J) mice F2 population.
Genome research 2001;11(12):2027-33.
2001: Lindberg M K; Alatalo S L; Halleen J M; Mohan S; Gustafsson J A; Ohlsson C
Estrogen receptor specificity in the regulation of the skeleton in female mice.
The Journal of endocrinology 2001;171(2):229-36.
2001: Schneider M R; Zhou R; Hoeflich A; Krebs O; Schmidt J; Mohan S; Wolf E; Lahm H
Insulin-like growth factor-binding protein-5 inhibits growth and induces differentiation of mouse osteosarcoma cells.
Biochemical and biophysical research communications 2001;288(2):435-42.
2001: Srivastava A K; Bhattacharyya S; Li X; Mohan S; Baylink D J
Circadian and longitudinal variation of serum C-telopeptide, osteocalcin, and skeletal alkaline phosphatase in C3H/HeJ mice.
Bone 2001;29(4):361-7.
2001: Miyakoshi N; Kasukawa Y; Linkhart T A; Baylink D J; Mohan S
Evidence that anabolic effects of PTH on bone require IGF-I in growing mice.
Endocrinology 2001;142(10):4349-56.
2001: Li X; Gu W; Masinde G; Hamilton-Ulland M; Rundle C H; Mohan S; Baylink D J
Genetic variation in bone-regenerative capacity among inbred strains of mice.
Bone 2001;29(2):134-40.
2001: Li X; Mohan S; Gu W; Wergedal J; Baylink D J
Quantitative assessment of forearm muscle size, forelimb grip strength, forearm bone mineral density, and forearm bone size in determining humerus breaking strength in 10 inbred strains of mice.
Calcified tissue international 2001;68(6):365-9.
2001: Li X; Gu W; Masinde G; Hamilton-Ulland M; Xu S; Mohan S; Baylink D J
Genetic control of the rate of wound healing in mice.
Heredity 2001;86(Pt 6):668-74.
2001: Miyakoshi N; Qin X; Kasukawa Y; Richman C; Srivastava A K; Baylink D J; Mohan S
Systemic administration of insulin-like growth factor (IGF)-binding protein-4 (IGFBP-4) increases bone formation parameters in mice by increasing IGF bioavailability via an IGFBP-4 protease-dependent mechanism.
Endocrinology 2001;142(6):2641-8.
2001: Richman C; Kutilek S; Miyakoshi N; Srivastava A K; Beamer W G; Donahue L R; Rosen C J; Wergedal J E; Baylink D J; Mohan S
Postnatal and pubertal skeletal changes contribute predominantly to the differences in peak bone density between C3H/HeJ and C57BL/6J mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(2):386-97.
2001: Byun D; Mohan S; Yoo M; Sexton C; Baylink D J; Qin X
Pregnancy-associated plasma protein-A accounts for the insulin-like growth factor (IGF)-binding protein-4 (IGFBP-4) proteolytic activity in human pregnancy serum and enhances the mitogenic activity of IGF by degrading IGFBP-4 in vitro.
The Journal of clinical endocrinology and metabolism 2001;86(2):847-54.
2001: Li X; Mohan S; Gu W; Baylink D J
Analysis of gene expression in the wound repair/regeneration process.
Mammalian genome : official journal of the International Mammalian Genome Society 2001;12(1):52-9.
2001: Miyakoshi N; Richman C; Kasukawa Y; Linkhart T A; Baylink D J; Mohan S
Evidence that IGF-binding protein-5 functions as a growth factor.
The Journal of clinical investigation 2001;107(1):73-81.
2000: Li X; Mohan S; Gu W; Miyakoshi N; Baylink D J
Differential protein profile in the ear-punched tissue of regeneration and non-regeneration strains of mice: a novel approach to explore the candidate genes for soft-tissue regeneration.
Biochimica et biophysica acta 2000;1524(2-3):102-9.
2000: Srivastava A K; Bhattacharyya S; Castillo G; Miyakoshi N; Mohan S; Baylink D J
Development and evaluation of C-telopeptide enzyme-linked immunoassay for measurement of bone resorption in mouse serum.
Bone 2000;27(4):529-33.
2000: Mohan S; Kutilek S; Zhang C; Shen H G; Kodama Y; Srivastava A K; Wergedal J E; Beamer W G; Baylink D J
Comparison of bone formation responses to parathyroid hormone(1-34), (1-31), and (2-34) in mice.
Bone 2000;27(4):471-8.
2000: Srivastava A K; Castillo G; Wergedal J E; Mohan S; Baylink D J
Development and application of a synthetic peptide-based osteocalcin assay for the measurement of bone formation in mouse serum.
Calcified tissue international 2000;67(3):255-9.
2000: Farley J; Dimai H P; Stilt-Coffing B; Farley P; Pham T; Mohan S
Calcitonin increases the concentration of insulin-like growth factors in serum-free cultures of human osteoblast-line cells.
Calcified tissue international 2000;67(3):247-54.
2000: Qin X; Byun D; Lau K H; Baylink D J; Mohan S
Evidence that the interaction between insulin-like growth factor (IGF)-II and IGF binding protein (IGFBP)-4 is essential for the action of the IGF-II-dependent IGFBP-4 protease.
Archives of biochemistry and biophysics 2000;379(2):209-16.
2000: Srivastava A K; Bhattacharyya S; Castillo G; Wergedal J; Mohan S; Baylink D J
Development and application of a serum C-telopeptide and osteocalcin assay to measure bone turnover in an ovariectomized rat model.
Calcified tissue international 2000;66(6):435-42.
2000: Vidal O; Lindberg M K; Hollberg K; Baylink D J; Andersson G; Lubahn D B; Mohan S; Gustafsson J A; Ohlsson C
Estrogen receptor specificity in the regulation of skeletal growth and maturation in male mice.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5474-9.
2000: Feldmann B; Jehle P M; Mohan S; Lang G E; Lang G K; Brueckel J; Boehm B O
Diabetic retinopathy is associated with decreased serum levels of free IGF-I and changes of IGF-binding proteins.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2000;10(1):53-9.
2000: Wagner M S; Stracke S; Jehle P M; Keller F; Zellner D; Baylink D J; Mohan S
Evaluation of IGF system component levels and mitogenic activity of uremic serum on normal human osteoblasts.
Nephron 2000;84(2):158-66.
2000: Jehle P M; Ostertag A; Schulten K; Schulz W; Jehle D R; Stracke S; Fiedler R; Deuber H J; Keller F; Boehm B O; Baylink D J; Mohan S
Insulin-like growth factor system components in hyperparathyroidism and renal osteodystrophy.
Kidney international 2000;57(2):423-36.
2000: Byun D; Mohan S; Kim C; Suh K; Yoo M; Lee H; Baylink D J; Qin X
Studies on human pregnancy-induced insulin-like growth factor (IGF)-binding protein-4 proteases in serum: determination of IGF-II dependency and localization of cleavage site.
The Journal of clinical endocrinology and metabolism 2000;85(1):373-81.
2000: Sjögren K; Bohlooly-Y M; Olsson B; Coschigano K; Törnell J; Mohan S; Isaksson O G; Baumann G; Kopchick J; Ohlsson C
Disproportional skeletal growth and markedly decreased bone mineral content in growth hormone receptor -/- mice.
Biochemical and biophysical research communications 2000;267(2):603-8.
1999: Qin X; Byun D; Strong D D; Baylink D J; Mohan S
Studies on the role of human insulin-like growth factor-II (IGF-II)-dependent IGF binding protein (hIGFBP)-4 protease in human osteoblasts using protease-resistant IGFBP-4 analogs.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(12):2079-88.
1999: Miyakoshi N; Richman C; Qin X; Baylink D J; Mohan S
Effects of recombinant insulin-like growth factor-binding protein-4 on bone formation parameters in mice.
Endocrinology 1999;140(12):5719-28.
1999: Hoeflich A; Wu M; Mohan S; Föll J; Wanke R; Froehlich T; Arnold G J; Lahm H; Kolb H J; Wolf E
Overexpression of insulin-like growth factor-binding protein-2 in transgenic mice reduces postnatal body weight gain.
Endocrinology 1999;140(12):5488-96.
1999: Richman C; Baylink D J; Lang K; Dony C; Mohan S
Recombinant human insulin-like growth factor-binding protein-5 stimulates bone formation parameters in vitro and in vivo.
Endocrinology 1999;140(10):4699-705.
1999: Cheng M z; Zaman G; Rawlinson S C; Mohan S; Baylink D J; Lanyon L E
Mechanical strain stimulates ROS cell proliferation through IGF-II and estrogen through IGF-I.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(10):1742-50.
1999: Boonyaratanakornkit V; Strong D D; Mohan S; Baylink D J; Beck C A; Linkhart T A
Progesterone stimulation of human insulin-like growth factor-binding protein-5 gene transcription in human osteoblasts is mediated by a CACCC sequence in the proximal promoter.
The Journal of biological chemistry 1999;274(37):26431-8.
1999: Hathout E H; Baylink D J; Mohan S
Normal growth despite GH, IGF-I and IGF-II deficiency.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 1999;9(4):272-7.
1999: Libanati C; Baylink D J; Lois-Wenzel E; Srinvasan N; Mohan S
Studies on the potential mediators of skeletal changes occurring during puberty in girls.
The Journal of clinical endocrinology and metabolism 1999;84(8):2807-14.
1999: Baylink D J; Strong D D; Mohan S
The diagnosis and treatment of osteoporosis: future prospects.
Molecular medicine today 1999;5(3):133-40.
1998: Jehle P M; Jehle D R; Mohan S; Böhm B O
Serum levels of insulin-like growth factor system components and relationship to bone metabolism in Type 1 and Type 2 diabetes mellitus patients.
The Journal of endocrinology 1998;159(2):297-306.
1998: Qin X; Strong D D; Baylink D J; Mohan S
Structure-function analysis of the human insulin-like growth factor binding protein-4.
The Journal of biological chemistry 1998;273(36):23509-16.
1998: Svensson J; Ohlsson C; Jansson J O; Murphy G; Wyss D; Krupa D; Cerchio K; Polvino W; Gertz B; Baylink D; Mohan S; Bengtsson B A
Treatment with the oral growth hormone secretagogue MK-677 increases markers of bone formation and bone resorption in obese young males.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1998;13(7):1158-66.
1998: Jehle P M; Jehle D R; Mohan S; Keller F
Renal osteodystrophy: new insights in pathophysiology and treatment modalities with special emphasis on the insulin-like growth factor system.
Nephron 1998;79(3):249-64.
1997: Srinivasan N; Baylink D J; Sampath K; Mohan S
Effects of inhibitors of signal transduction pathways on transforming growth factor beta1 and osteogenic protein-1-induced insulinlike growth factor binding protein-3 expression in human bone cells.
Journal of cellular physiology 1997;173(1):28-35.
1997: Hayden J M; Strong D D; Baylink D J; Powell D R; Sampath T K; Mohan S
Osteogenic protein-1 stimulates production of insulin-like growth factor binding protein-3 nuclear transcripts in human osteosarcoma cells.
Endocrinology 1997;138(10):4240-7.
1997: Rosen C J; Dimai H P; Vereault D; Donahue L R; Beamer W G; Farley J; Linkhart S; Linkhart T; Mohan S; Baylink D J
Circulating and skeletal insulin-like growth factor-I (IGF-I) concentrations in two inbred strains of mice with different bone mineral densities.
Bone 1997;21(3):217-23.
1997: Malpe R; Baylink D J; Linkhart T A; Wergedal J E; Mohan S
Insulin-like growth factor (IGF)-I, -II, IGF binding proteins (IGFBP)-3, -4, and -5 levels in the conditioned media of normal human bone cells are skeletal site-dependent.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(3):423-30.
1997: Honda Y; Knutsen R; Strong D D; Sampath T K; Baylink D J; Mohan S
Osteogenic protein-1 stimulates mRNA levels of BMP-6 and decreases mRNA levels of BMP-2 and -4 in human osteosarcoma cells.
Calcified tissue international 1997;60(3):297-301.
1997: Qin X; Morales S; Lee K W; Boonyaratanakornkit V; Baylink D J; Mohan S; Strong D D
Structural and functional analysis of the 5'-flanking region of the human insulin-like growth factor binding protein (IGFBP)-4 gene.
Biochimica et biophysica acta 1997;1350(2):136-40.
1996: Baylink T M; Mohan S; Fitzsimmons R J; Baylink D J
Evaluation of signal transduction mechanisms for the mitogenic effects of prostaglandin E2 in normal human bone cells in vitro.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(10):1413-8.
1996: Linkhart T A; Mohan S; Baylink D J
Growth factors for bone growth and repair: IGF, TGF beta and BMP.
Bone 1996;19(1 Suppl):1S-12S.
1996: Srinivasan N; Edwall D; Linkhart T A; Baylink D J; Mohan S
Insulin-like growth factor-binding protein-6 produced by human PC-3 prostate cancer cells: isolation, characterization and its biological action.
The Journal of endocrinology 1996;149(2):297-303.
1996: Chevalley T; Strong D D; Mohan S; Baylink D; Linkhart T A
Evidence for a role for insulin-like growth factor binding proteins in glucocorticoid inhibition of normal human osteoblast-like cell proliferation.
European journal of endocrinology / European Federation of Endocrine Societies 1996;134(5):591-601.
1996: Honda Y; Landale E C; Strong D D; Baylink D J; Mohan S
Recombinant synthesis of insulin-like growth factor-binding protein-4 (IGFBP-4): Development, validation, and application of a radioimmunoassay for IGFBP-4 in human serum and other biological fluids.
The Journal of clinical endocrinology and metabolism 1996;81(4):1389-96.
1996: Zhou Y; Mohan S; Linkhart T A; Baylink D J; Strong D D
Retinoic acid regulates insulin-like growth factor-binding protein expression in human osteoblast cells.
Endocrinology 1996;137(3):975-83.
1996: Mohan S; Baylink D J
Insulin-like growth factor system components and the coupling of bone formation to resorption.
Hormone research 1996;45 Suppl 1():59-62.
1995: Honda Y; Fitzsimmons R J; Baylink D J; Mohan S
Effects of extracellular calcium on insulin-like growth factor II in human bone cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1995;10(11):1660-5.
1995: Mohan S; Libanati C; Dony C; Lang K; Srinivasan N; Baylink D J
Development, validation, and application of a radioimmunoassay for insulin-like growth factor binding protein-5 in human serum and other biological fluids.
The Journal of clinical endocrinology and metabolism 1995;80(9):2638-45.
1995: Mohan S; Nakao Y; Honda Y; Landale E; Leser U; Dony C; Lang K; Baylink D J
Studies on the mechanisms by which insulin-like growth factor (IGF) binding protein-4 (IGFBP-4) and IGFBP-5 modulate IGF actions in bone cells.
The Journal of biological chemistry 1995;270(35):20424-31.
1995: Hayden J M; Mohan S; Baylink D J
The insulin-like growth factor system and the coupling of formation to resorption.
Bone 1995;17(2 Suppl):93S-98S.
1995: Fitzsimmons R J; Ryaby J T; Mohan S; Magee F P; Baylink D J
Combined magnetic fields increase insulin-like growth factor-II in TE-85 human osteosarcoma bone cell cultures.
Endocrinology 1995;136(7):3100-6.
1995: Kanzaki S; Baxter R C; Knutsen R; Baylink D J; Mohan S
Evidence that human bone cells in culture secrete insulin-like growth factor (IGF)-II and IGF binding protein-3 but not acid-labile subunit both under basal and regulated conditions.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1995;10(6):854-8.
1995: Tabuenca A; Mohan S; Garberoglio C A; Borgen P I; Rosol T; Linkhart T A
Parathyroid hormone-related protein: primary osteolytic factor produced by breast tumor cells in vitro?
World journal of surgery 1995;19(2):292-7; discussion 297-8.
1995: Knutsen R; Honda Y; Strong D D; Sampath T K; Baylink D J; Mohan S
Regulation of insulin-like growth factor system components by osteogenic protein-1 in human bone cells.
Endocrinology 1995;136(3):857-65.
1995: Mohan S; Baylink D J
Development of a simple valid method for the complete removal of insulin-like growth factor (IGF)-binding proteins from IGFs in human serum and other biological fluids: comparison with acid-ethanol treatment and C18 Sep-Pak separation.
The Journal of clinical endocrinology and metabolism 1995;80(2):637-47.
1995: Landale E C; Strong D D; Mohan S; Baylink D J
Sequence comparison and predicted structure for the four exon-encoded regions of human insulin-like growth factor binding protein 4.
Growth factors (Chur, Switzerland) 1995;12(4):245-50.
1995: Mohan S; Farley J R; Baylink D J
Age-related changes in IGFBP-4 and IGFBP-5 levels in human serum and bone: implications for bone loss with aging.
Progress in growth factor research 1995;6(2-4):465-73.
1994: Strong D D; Merriman H L; Landale E C; Baylink D J; Mohan S
The effects of the insulin-like growth factors and transforming growth factor beta on the Jun proto-oncogene family in MC3T3-E1 cells.
Calcified tissue international 1994;55(4):311-5.
1994: Scharla S H; Strong D D; Mohan S; Chevalley T; Linkhart T A
Effect of tumor necrosis factor-alpha on the expression of insulin-like growth factor I and insulin-like growth factor binding protein 4 in mouse osteoblasts.
European journal of endocrinology / European Federation of Endocrine Societies 1994;131(3):293-301.
1994: Malpe R; Baylink D J; Sampath T K; Mohan S
Evidence that human bone cells in culture contain binding sites for osteogenic protein-1.
Biochemical and biophysical research communications 1994;201(3):1140-7.
1994: Nakao Y; Hilliker S; Baylink D J; Mohan S
Studies on the regulation of insulin-like growth factor binding protein 3 secretion in human osteosarcoma cells in vitro.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994;9(6):865-72.
1994: Kanzaki S; Hilliker S; Baylink D J; Mohan S
Evidence that human bone cells in culture produce insulin-like growth factor-binding protein-4 and -5 proteases.
Endocrinology 1994;134(1):383-92.
1993: Baylink D J; Finkelman R D; Mohan S
Growth factors to stimulate bone formation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1993;8 Suppl 2():S565-72.
1993: Scharla S H; Strong D D; Rosen C; Mohan S; Holick M; Baylink D J; Linkhart T A
1,25-Dihydroxyvitamin D3 increases secretion of insulin-like growth factor binding protein-4 (IGFBP-4) by human osteoblast-like cells in vitro and elevates IGFBP-4 serum levels in vivo.
The Journal of clinical endocrinology and metabolism 1993;77(5):1190-7.
1993: Mohan S; Strong D D; Hilliker S; Malpe R; Lee K; Farley J; Baylink D J
Dibutyryl cyclic adenosine monophosphate differentially regulates cell proliferation in low and high alkaline phosphatase SaOS-2 human osteosarcoma cells: evidence for mediation by the insulin-like growth factor-II system.
Journal of cellular physiology 1993;156(3):462-8.
1993: Knutsen R; Wergedal J E; Sampath T K; Baylink D J; Mohan S
Osteogenic protein-1 stimulates proliferation and differentiation of human bone cells in vitro.
Biochemical and biophysical research communications 1993;194(3):1352-8.
1993: Lau K H; Utrapiromsuk S; Yoo A; Mohan S; Strong D D; Baylink D J
Mechanism of mitogenic action of aluminum ion on human bone cells: potential involvement of the insulin-like growth factor regulatory system.
Archives of biochemistry and biophysics 1993;303(2):267-73.
1993: Schiltz P M; Mohan S; Baylink D J
Insulin-like growth factor binding protein-4 inhibits both basal and IGF-mediated chick pelvic cartilage growth in vitro.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1993;8(4):391-6.
1993: Mohan S
Insulin-like growth factor binding proteins in bone cell regulation.
Growth regulation 1993;3(1):67-70.
1993: Amarnani S; Merriman H L; Linkhart T A; Baylink D J; Mohan S
Autocrine regulators of MC3T3-E1 cell proliferation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1993;8(2):157-65.
1993: Oberbauer A M; Strong D D; Linkhart T A; Mohan S; Longo L D
Fibroblast growth factor enhances the transcription and stability of human chorionic gonadotropin beta-subunit messenger ribonucleic acid in Jar choriocarcinoma cells.
Endocrinology 1993;132(2):757-62.
1993: Mohan S; Baylink D J
Characterization of the IGF regulatory system in bone.
Advances in experimental medicine and biology 1993;343():397-406.
1992: Mohan S; Strong D D; Lempert U G; Tremollieres F; Wergedal J E; Baylink D J
Studies on regulation of insulin-like growth factor binding protein (IGFBP)-3 and IGFBP-4 production in human bone cells.
Acta endocrinologica 1992;127(6):555-64.
1992: Tremollieres F A; Strong D D; Baylink D J; Mohan S
Progesterone and promegestone stimulate human bone cell proliferation and insulin-like growth factor-2 production.
Acta endocrinologica 1992;126(4):329-37.
1992: Finkelman R D; Mohan S; Linkhart T A; Abraham S M; Boussy J P; Baylink D J
PTH stimulates the proliferation of TE-85 human osteosarcoma cells by a mechanism not involving either increased cAMP or increased secretion of IGF-I, IGF-II or TGF beta.
Bone and mineral 1992;16(2):89-100.
1992: Fitzsimmons R J; Strong D D; Mohan S; Baylink D J
Low-amplitude, low-frequency electric field-stimulated bone cell proliferation may in part be mediated by increased IGF-II release.
Journal of cellular physiology 1992;150(1):84-9.
1992: Rosen C; Donahue L R; Hunter S; Holick M; Kavookjian H; Kirschenbaum A; Mohan S; Baylink D J
The 24/25-kDa serum insulin-like growth factor-binding protein is increased in elderly women with hip and spine fractures.
The Journal of clinical endocrinology and metabolism 1992;74(1):24-7.
1992: Schiltz P M; Ohta T; Glass D; Mohan S; Baylink D J
Growth hormone stimulates cortical bone formation in immature hypophysectomized rats.
Endocrine research 1992;18(1):19-30.
1991: Scharla S H; Strong D D; Mohan S; Baylink D J; Linkhart T A
1,25-Dihydroxyvitamin D3 differentially regulates the production of insulin-like growth factor I (IGF-I) and IGF-binding protein-4 in mouse osteoblasts.
Endocrinology 1991;129(6):3139-46.
1991: Tremollieres F A; Strong D D; Baylink D J; Mohan S
Insulin-like growth factor II and transforming growth factor beta 1 regulate insulin-like growth factor I secretion in mouse bone cells.
Acta endocrinologica 1991;125(5):538-46.
1991: Mohan S; Baylink D J
Evidence that the inhibition of TE85 human bone cell proliferation by agents which stimulate cAMP production may in part be mediated by changes in the IGF-II regulatory system.
Growth regulation 1991;1(3):110-8.
1991: Finkelman R D; Linkhart T A; Mohan S; Lau K H; Baylink D J; Bell N H
Vitamin D deficiency causes a selective reduction in deposition of transforming growth factor beta in rat bone: possible mechanism for impaired osteoinduction.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(9):3657-60.
1991: Bautista C M; Baylink D J; Mohan S
Isolation of a novel insulin-like growth factor (IGF) binding protein from human bone: a potential candidate for fixing IGF-II in human bone.
Biochemical and biophysical research communications 1991;176(2):756-63.
1991: Mohan S; Baylink D J
Bone growth factors.
Clinical orthopaedics and related research 1991;(263):30-48.
1991: Lau K H; Stepan J J; Yoo A; Mohan S; Baylink D J
Evidence that tartrate-resistant acid phosphatases from osteoclastomas and hairy cell leukemia spleen are members of a multigene family.
The International journal of biochemistry 1991;23(11):1237-44.
1991: Stepan J J; Mohan S; Jennings J C; Wergedal J E; Taylor A K; Baylink D J
Quantitation of growth factors in ossein-mineral-compound.
Life sciences 1991;49(13):PL79-84.
1990: LaTour D; Mohan S; Linkhart T A; Baylink D J; Strong D D
Inhibitory insulin-like growth factor-binding protein: cloning, complete sequence, and physiological regulation.
Molecular endocrinology (Baltimore, Md.) 1990;4(12):1806-14.
1990: Perkel V S; Mohan S; Herring S J; Baylink D J; Linkhart T A
Human prostatic cancer cells, PC3, elaborate mitogenic activity which selectively stimulates human bone cells.
Cancer research 1990;50(21):6902-7.
1990: Perkel V S; Mohan S; Baylink D J; Linkhart T A
An inhibitory insulin-like growth factor binding protein (In-IGFBP) from human prostatic cell conditioned medium reveals N-terminal sequence identity with bone derived In-IGFBP.
The Journal of clinical endocrinology and metabolism 1990;71(2):533-5.
1990: Finkelman R D; Mohan S; Jennings J C; Taylor A K; Jepsen S; Baylink D J
Quantitation of growth factors IGF-I, SGF/IGF-II, and TGF-beta in human dentin.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1990;5(7):717-23.
1990: Mohan S; Bautista C M; Herring S J; Linkhart T A; Baylink D J
Development of valid methods to measure insulin-like growth factors-I and -II in bone cell-conditioned medium.
Endocrinology 1990;126(5):2534-42.
1990: Stepan J J; Lau K H; Mohan S; Singer F R; Baylink D J
Purification and N-terminal amino acid sequence of the tartrate-resistant acid phosphatase from human osteoclastoma: evidence for a single structure.
Biochemical and biophysical research communications 1990;168(2):792-800.
1990: Merriman H L; La Tour D; Linkhart T A; Mohan S; Baylink D J; Strong D D
Insulin-like growth factor-I and insulin-like growth factor-II induce c-fos in mouse osteoblastic cells.
Calcified tissue international 1990;46(4):258-62.
1990: Taylor A K; Linkhart S; Mohan S; Christenson R A; Singer F R; Baylink D J
Multiple osteocalcin fragments in human urine and serum as detected by a midmolecule osteocalcin radioimmunoassay.
The Journal of clinical endocrinology and metabolism 1990;70(2):467-72.
1990: Wergedal J E; Mohan S; Lundy M; Baylink D J
Skeletal growth factor and other growth factors known to be present in bone matrix stimulate proliferation and protein synthesis in human bone cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1990;5(2):179-86.
1990: Jennings J C; Mohan S
Heterogeneity of latent transforming growth factor-beta isolated from bone matrix proteins.
Endocrinology 1990;126(2):1014-21.
1990: Bautista C M; Mohan S; Baylink D J
Insulin-like growth factors I and II are present in the skeletal tissues of ten vertebrates.
Metabolism: clinical and experimental 1990;39(1):96-100.
1990: Mohan S
A simple and efficient scheme for the purification of insulin-like growth factor II from human bone matrix extract.
Growth factors (Chur, Switzerland) 1990;2(4):267-71.
1989: Stepán J J; Lau K H; Mohan S; Kraenzlin M; Baylink D J
Purification and N-terminal sequence of two tartrate-resistant acid phosphatases type-5 from the hairy cell leukemia spleen.
Biochemical and biophysical research communications 1989;165(3):1027-34.
1989: Mohan S; Bautista C M; Wergedal J; Baylink D J
Isolation of an inhibitory insulin-like growth factor (IGF) binding protein from bone cell-conditioned medium: a potential local regulator of IGF action.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(21):8338-42.
1989: Linkhart T A; Mohan S
Parathyroid hormone stimulates release of insulin-like growth factor-I (IGF-I) and IGF-II from neonatal mouse calvaria in organ culture.
Endocrinology 1989;125(3):1484-91.
1989: Jennings J C; Mohan S; Baylink D J
Beta 2-microglobulin is not a bone cell mitogen.
Endocrinology 1989;125(1):404-9.
1989: Mohan S; Linkhart T; Rosenfeld R; Baylink D
Characterization of the receptor for insulin-like growth factor II in bone cells.
Journal of cellular physiology 1989;140(1):169-76.
1989: Linkhart T A; Mohan S; Jennings J C; Baylink D J
Copurification of osteolytic and transforming growth factor beta activities produced by human lung tumor cells associated with humoral hypercalcemia of malignancy.
Cancer research 1989;49(2):271-8.
1988: Oberbauer A M; Linkhart T A; Mohan S; Longo L D
Fibroblast growth factor enhances human chorionic gonadotropin synthesis independent of mitogenic stimulation in Jar choriocarcinoma cells.
Endocrinology 1988;123(6):2696-700.
1988: Jennings J C; Mohan S; Linkhart T A; Widstrom R; Baylink D J
Comparison of the biological actions of TGF beta-1 and TGF beta-2: differential activity in endothelial cells.
Journal of cellular physiology 1988;137(1):167-72.
1988: Taylor A K; Linkhart S G; Mohan S; Baylink D J
Development of a new radioimmunoassay for human osteocalcin: evidence for a midmolecule epitope.
Metabolism: clinical and experimental 1988;37(9):872-7.
1988: Mohan S; Jennings J C; Linkhart T A; Baylink D J
Primary structure of human skeletal growth factor: homology with human insulin-like growth factor-II.
Biochimica et biophysica acta 1988;966(1):44-55.
1988: Linkhart T A; Mohan S; Baylink D J
Bone repletion in vitro: evidence for a locally regulated bone repair response to PTH treatment.
Bone 1988;9(6):371-9.
1986: Mohan S; Jennings J C; Linkhart T A; Baylink D J
Isolation and purification of a low-molecular-weight skeletal growth factor from human bones.
Biochimica et biophysica acta 1986;884(2):234-42.
1986: Linkhart S; Mohan S; Linkhart T A; Kumegawa M; Baylink D J
Human skeletal growth factor stimulates collagen synthesis and inhibits proliferation in a clonal osteoblast cell line (MC3T3-E1).
Journal of cellular physiology 1986;128(2):307-12.
1986: Linkhart T A; Jennings J C; Mohan S; Wakley G K; Baylink D J
Characterization of mitogenic activities extracted from bovine bone matrix.
Bone 1986;7(6):479-87.
1984: Mohan S; Linkhart T; Farley J; Baylink D
Bone-derived factors active on bone cells.
Calcified tissue international 1984;36 Suppl 1():S139-45.

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