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Søren Molin

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Søren Damkiær; Søren Molin; Lei Yang; Lars Jelsbak
Evolutionary remodeling of global regulatory networks during long-term bacterial adaptation to human hosts.
Yang Liu; Søren Molin; Liang Yang; Henrik Franzyk; Kolja M Knapp; Anders Folkesson
High in vitro antimicrobial activity of β-peptoid-peptide hybrid oligomers against planktonic and biofilm cultures of Staphylococcus epidermidis.
Anders Folkesson; Niels Høiby; Lars Jelsbak; Helle Krogh Johansen; Oana Ciofu; Lei Yang; Søren Molin
Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective.

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All Publications

2013: Søren Damkiær; Søren Molin; Lei Yang; Lars Jelsbak
Evolutionary remodeling of global regulatory networks during long-term bacterial adaptation to human hosts.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(19):7766-71.
2013: Yang Liu; Søren Molin; Liang Yang; Henrik Franzyk; Kolja M Knapp; Anders Folkesson
High in vitro antimicrobial activity of β-peptoid-peptide hybrid oligomers against planktonic and biofilm cultures of Staphylococcus epidermidis.
International journal of antimicrobial agents 2013;41(1):20-7.
2012: Anders Folkesson; Niels Høiby; Lars Jelsbak; Helle Krogh Johansen; Oana Ciofu; Lei Yang; Søren Molin
Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective.
Nature reviews. Microbiology 2012;10(12):841-51.
2012: Martin H Rau; Garth D Ehrlich; Rasmus Lykke Marvig; Søren Molin; Lars Jelsbak
Deletion and acquisition of genomic content during early stage adaptation of Pseudomonas aeruginosa to a human host environment.
Environmental microbiology 2012;14(8):2200-11.
2012: Rasmus Lykke Marvig; Søren Molin; Mette S R Søndergaard; Søren Damkiær; Niels Høiby; Helle Krogh Johansen; Lars Jelsbak
Mutations in 23S rRNA confer resistance against azithromycin in Pseudomonas aeruginosa.
Antimicrobial agents and chemotherapy 2012;56(8):4519-21.
2012: María Gómez-Lozano; Rasmus Lykke Marvig; Søren Molin; Katherine S Long
Genome-wide identification of novel small RNAs in Pseudomonas aeruginosa.
Environmental microbiology 2012;14(8):2006-16.
2012: Liang Yang; Zhijun Song; Hong Wu; Søren Damkiaer; Michael Givskov; Wang Hengzhuang; Niels Høiby; Nicholas Jochumsen; Søren Molin
Polysaccharides serve as scaffold of biofilms formed by mucoid Pseudomonas aeruginosa.
FEMS immunology and medical microbiology 2012;65(2):366-76.
2012: Liang Yang; Niels Høiby; Yang Liu; Søren Molin; Zhijun Song; Hong Wu; Michael Givskov
Combating biofilms.
FEMS immunology and medical microbiology 2012;65(2):146-57.
2012: Robert Sautter; Lisa Schneper; Tina Wassermann; Søren Molin; Dennis E Ohman; Damaris Ramos; Oana Ciofu; Caroline A Devries; Morten Hentzer; Arne Heydorn; Niels Høiby; Arsalan Kharazmi; Chong-Lek Koh; Kalai Mathee
A complex multilevel attack on Pseudomonas aeruginosa algT/U expression and algT/U activity results in the loss of alginate production.
Gene 2012;498(2):242-53.
2011: Nicholas Jochumsen; Yang Liu; Søren Molin; Anders Folkesson
A Mig-14-like protein (PA5003) affects antimicrobial peptide recognition in Pseudomonas aeruginosa.
Microbiology (Reading, England) 2011;157(Pt 9):2647-57.
2011: Liang Yang; Jingdong Zhang; Yifan Hu; Yang Liu; Jens Ulstrup; Søren Molin
Distinct roles of extracellular polymeric substances in Pseudomonas aeruginosa biofilm development.
Environmental microbiology 2011;13(7):1705-17.
2011: Lei Yang; Lars Jelsbak; Søren Molin
Microbial ecology and adaptation in cystic fibrosis airways.
Environmental microbiology 2011;13(7):1682-9.
2011: Yifan Hu; Jens Ulstrup; Jingdong Zhang; Søren Molin; Vincent Dupres
Adhesive properties of Staphylococcus epidermidis probed by atomic force microscopy.
Physical chemistry chemical physics : PCCP 2011;13(21):9995-10003.
2011: Hong Wu; Baoleri Lee; Liang Yang; Hengzuang Wang; Michael Givskov; Søren Molin; Niels Høiby; Zhijun Song
Effects of ginseng on Pseudomonas aeruginosa motility and biofilm formation.
FEMS immunology and medical microbiology 2011;62(1):49-56.
2011: Lei Yang; Lars Jelsbak; Rasmus Lykke Marvig; Søren Damkiær; Christopher T Workman; Martin Holm Rau; Susse Kirkelund Hansen; Anders Folkesson; Helle Krogh Johansen; Oana Ciofu; Niels Høiby; Morten O A Sommer; Søren Molin
Evolutionary dynamics of bacteria in a human host environment.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(18):7481-6.
2011: Baoleri Lee; Charlotte K Schjerling; Nikolai Kirkby; Nadine Hoffmann; Rehannah Borup; Søren Molin; Niels Høiby; Oana Ciofu
Mucoid Pseudomonas aeruginosa isolates maintain the biofilm formation capacity and the gene expression profiles during the chronic lung infection of CF patients.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2011;119(4-5):263-74.
2011: Liang Yang; Hong Wu; Niels Hóiby; Yang Liu; Søren Molin; Zhi-jun Song
Current understanding of multi-species biofilms.
International journal of oral science 2011;3(2):74-81.
2011: Niels Høiby; Peter Østrup Jensen; Helle Krogh Johansen; Søren Molin; Claus Moser; Zhi-jun Song; Tim Tolker-Nielsen; Oana Ciofu; Michael Givskov; Thomas Bjarnsholt
The clinical impact of bacterial biofilms.
International journal of oral science 2011;3(2):55-65.
2011: Caroline Giraud; Christophe S Bernard; Virginie Calderon; Liang Yang; Alain Filloux; Søren Molin; Gwennaele Fichant; Christophe Bordi; Sophie de Bentzmann
The PprA-PprB two-component system activates CupE, the first non-archetypal Pseudomonas aeruginosa chaperone-usher pathway system assembling fimbriae.
Environmental microbiology 2011;13(3):666-83.
2011: Morten Alhede; Marie Allesen-Holm; Lisa D Christensen; Michael Givskov; Niels Høiby; Peter Østrup Jensen; Kasper Nørskov Kragh; Søren Molin; Anne K Nielsen; Matt Parsek; Klaus Qvortrup; Tim Tolker-Nielsen; Maria van Gennip; Dan Wozniak; Thomas Bjarnsholt
Phenotypes of non-attached Pseudomonas aeruginosa aggregates resemble surface attached biofilm.
PloS one 2011;6(11):e27943.
2011: Lei Yang; Liang Yang; Niels Høiby; Søren Molin; Martin Holm Rau; Lars Jelsbak
Bacterial adaptation during chronic infection revealed by independent component analysis of transcriptomic data.
BMC microbiology 2011;11():184.
2010: Gloria Herrmann; Liang Yang; Hong Wu; Zhijun Song; Hengzhuang Wang; Niels Høiby; Martina Ulrich; Søren Molin; Joachim Riethmüller; Gerd Döring
Colistin-tobramycin combinations are superior to monotherapy concerning the killing of biofilm Pseudomonas aeruginosa.
The Journal of infectious diseases 2010;202(10):1585-92.
2010: Yang Liu; Liang Yang; Søren Molin
Synergistic activities of an efflux pump inhibitor and iron chelators against Pseudomonas aeruginosa growth and biofilm formation.
Antimicrobial agents and chemotherapy 2010;54(9):3960-3.
2010: Maciej Skolimowski; Martin Weiss Nielsen; Jenny Emnéus; Søren Molin; Rafael Taboryski; Claus Sternberg; Martin Dufva; Oliver Geschke
Microfluidic dissolved oxygen gradient generator biochip as a useful tool in bacterial biofilm studies.
Lab on a chip 2010;10(16):2162-9.
2010: Martin Holm Rau; Susse Kirkelund Hansen; Helle Krogh Johansen; Line Elnif Thomsen; Christopher T Workman; Kristian Fog Nielsen; Lars Jelsbak; Niels Høiby; Lei Yang; Søren Molin
Early adaptive developments of Pseudomonas aeruginosa after the transition from life in the environment to persistent colonization in the airways of human cystic fibrosis hosts.
Environmental microbiology 2010;12(6):1643-58.
2010: Niels Høiby; Thomas Bjarnsholt; Michael Givskov; Søren Molin; Oana Ciofu
Antibiotic resistance of bacterial biofilms.
International journal of antimicrobial agents 2010;35(4):322-32.
2010: Martin Lappann; Heike Claus; Tessa van Alen; Morten Harmsen; Johannes Elias; Søren Molin; Ulrich Vogel
A dual role of extracellular DNA during biofilm formation of Neisseria meningitidis.
Molecular microbiology 2010;75(6):1355-71.
2010: Liang Yang; Yang Liu; Claus Sternberg; Søren Molin
Evaluation of enoyl-acyl carrier protein reductase inhibitors as Pseudomonas aeruginosa quorum-quenching reagents.
Molecules (Basel, Switzerland) 2010;15(2):780-92.
2009: Maria van Gennip; Claus Moser; Louise D Christensen; Thomas Bjarnsholt; Henrik Calum; Peter Østrup Jensen; Lars Christophersen; Hans Petter Hougen; Oana Ciofu; Søren Molin; Michael Givskov; Niels Høiby
Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa.
The Journal of antimicrobial chemotherapy 2009;64(6):1241-50.
2009: Zhiqiang Qin; Jingdong Zhang; Yifan Hu; Qijin Chi; Ninell P Mortensen; Di Qu; Søren Molin; Jens Ulstrup
Organic compounds inhibiting S. epidermidis adhesion and biofilm formation.
Ultramicroscopy 2009;109(8):881-8.
2009: Claus Moser; Maria Van Gennip; Thomas Bjarnsholt; Peter Østrup Jensen; Baoleri Lee; Hans Petter Hougen; Henrik Calum; Oana Ciofu; Michael Givskov; Søren Molin; Niels Høiby
Novel experimental Pseudomonas aeruginosa lung infection model mimicking long-term host-pathogen interactions in cystic fibrosis.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2009;117(2):95-107.
2008: Lei Yang; Janus A J Haagensen; Lars Jelsbak; Helle Krogh Johansen; Claus Sternberg; Niels Høiby; Søren Molin
In situ growth rates and biofilm development of Pseudomonas aeruginosa populations in chronic lung infections.
Journal of bacteriology 2008;190(8):2767-76.
2008: Anders Folkesson; Janus A J Haagensen; Claudia Zampaloni; Claus Sternberg; Søren Molin
Biofilm induced tolerance towards antimicrobial peptides.
PloS one 2008;3(4):e1891.
2007: Susse Kirkelund Hansen; Janus A J Haagensen; Morten Gjermansen; Thomas Martini Jørgensen; Tim Tolker-Nielsen; Søren Molin
Characterization of a Pseudomonas putida rough variant evolved in a mixed-species biofilm with Acinetobacter sp. strain C6.
Journal of bacteriology 2007;189(13):4932-43.
2007: Lars Jelsbak; Helle Krogh Johansen; Anne-Louise Frost; Regitze Thøgersen; Line E Thomsen; Oana Ciofu; Lei Yang; Janus A J Haagensen; Niels Høiby; Søren Molin
Molecular epidemiology and dynamics of Pseudomonas aeruginosa populations in lungs of cystic fibrosis patients.
Infection and immunity 2007;75(5):2214-24.
2007: Susse Kirkelund Hansen; Paul B Rainey; Janus A J Haagensen; Søren Molin
Evolution of species interactions in a biofilm community.
Nature 2007;445(7127):533-6.
2007: Lars Mølbak; Søren Molin; Niels Kroer
Root growth and exudate production define the frequency of horizontal plasmid transfer in the Rhizosphere.
FEMS microbiology ecology 2007;59(1):167-76.
2007: Janus A J Haagensen; Mikkel Klausen; Robert Ernst; Samuel I Miller; Anders Folkesson; Tim Tolker-Nielsen; Søren Molin
Differentiation and distribution of colistin- and sodium dodecyl sulfate-tolerant cells in Pseudomonas aeruginosa biofilms.
Journal of bacteriology 2007;189(1):28-37.
2006: Martin Lappann; Janus A J Haagensen; Heike Claus; Ulrich Vogel; Søren Molin
Meningococcal biofilm formation: structure, development and phenotypes in a standardized continuous flow system.
Molecular microbiology 2006;62(5):1292-309.
2006: Heike Laue; Alexander Schenk; Hongqiao Li; Lotte Lambertsen; Thomas Neu; Søren Molin; Matthias S Ullrich
Contribution of alginate and levan production to biofilm formation by Pseudomonas syringae.
Microbiology (Reading, England) 2006;152(Pt 10):2909-18.
2006: Andreas Reisner; Brigitte M Höller; Søren Molin; Ellen L Zechner
Synergistic effects in mixed Escherichia coli biofilms: conjugative plasmid transfer drives biofilm expansion.
Journal of bacteriology 2006;188(10):3582-8.
2006: Andreas Reisner; Karen A Krogfelt; Bjarke M Klein; Ellen L Zechner; Søren Molin
In vitro biofilm formation of commensal and pathogenic Escherichia coli strains: impact of environmental and genetic factors.
Journal of bacteriology 2006;188(10):3572-81.
2006: Jörg Mampel; Thomas Spirig; Stefan S Weber; Janus A J Haagensen; Søren Molin; Hubert Hilbi
Planktonic replication is essential for biofilm formation by Legionella pneumophila in a complex medium under static and dynamic flow conditions.
Applied and environmental microbiology 2006;72(4):2885-95.
2006: Marie Allesen-Holm; Kim Barken; Liang Yang; Mikkel Klausen; Jeremy S Webb; Staffan Kjelleberg; Søren Molin; Michael Givskov; Tim Tolker-Nielsen
A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms.
Molecular microbiology 2006;59(4):1114-28.
2005: Adam C Martiny; Hans-Jørgen Albrechtsen; Erik Arvin; Søren Molin
Identification of bacteria in biofilm and bulk water samples from a nonchlorinated model drinking water distribution system: detection of a large nitrite-oxidizing population associated with Nitrospira spp.
Applied and environmental microbiology 2005;71(12):8611-7.
2005: Raul Fernandez-Lopez; Cristina Machón; Christopher Longshaw; Steve Martin; Søren Molin; Ellen L Zechner; Manuel Espinosa; Erich Lanka; Fernando de la Cruz
Unsaturated fatty acids are inhibitors of bacterial conjugation.
Microbiology (Reading, England) 2005;151(Pt 11):3517-26.
2005: Baoleri Lee; Janus A J Haagensen; Oana Ciofu; Jens Bo Andersen; Niels Høiby; Søren Molin
Heterogeneity of biofilms formed by nonmucoid Pseudomonas aeruginosa isolates from patients with cystic fibrosis.
Journal of clinical microbiology 2005;43(10):5247-55.
2005: Morten Gjermansen; Paula Ragas; Claus Sternberg; Søren Molin; Tim Tolker-Nielsen
Characterization of starvation-induced dispersion in Pseudomonas putida biofilms.
Environmental microbiology 2005;7(6):894-906.
2005: Nadine Hoffmann; Thomas Bovbjerg Rasmussen; Peter Østrup Jensen; Charlotte Stub; Morten Hentzer; Søren Molin; Oana Ciofu; Michael Givskov; Helle Krogh Johansen; Niels Høiby
Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis.
Infection and immunity 2005;73(4):2504-14.
2005: Thomas Bjarnsholt; Peter Østrup Jensen; Mette Burmølle; Morten Hentzer; Janus A J Haagensen; Hans Petter Hougen; Henrik Calum; Kit G Madsen; Claus Moser; Søren Molin; Niels Høiby; Michael Givskov
Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent.
Microbiology (Reading, England) 2005;151(Pt 2):373-83.
2005: Andreas Reisner; Niels Høiby; Tim Tolker-Nielsen; Søren Molin
Microbial pathogenesis and biofilm development.
Contributions to microbiology 2005;12():114-31.
2004: Lotte Lambertsen; Søren Molin; Niels Kroer; Christopher M Thomas
Transcriptional regulation of pWW0 transfer genes in Pseudomonas putida KT2440.
Plasmid 2004;52(3):169-81.
2004: Erin Werner; Frank Roe; Amandine Bugnicourt; Michael J Franklin; Arne Heydorn; Søren Molin; Betsey Pitts; Philip S Stewart
Stratified growth in Pseudomonas aeruginosa biofilms.
Applied and environmental microbiology 2004;70(10):6188-96.
2004: Lotte Lambertsen; Claus Sternberg; Søren Molin
Mini-Tn7 transposons for site-specific tagging of bacteria with fluorescent proteins.
Environmental microbiology 2004;6(7):726-32.
2004: Andres Plata Stapper; Giri Narasimhan; Dennis Ohman; Johnny Barakat; Morten Hentzer; Søren Molin; Arsalan Kharazmi; Niels Høiby; Kalai Mathee
Alginate production affects Pseudomonas aeruginosa biofilm development and architecture, but is not essential for biofilm formation.
Journal of medical microbiology 2004;53(Pt 7):679-90.
2004: H Wu; Zhijun Song; Morten Hentzer; Jens Bo Andersen; Søren Molin; Michael Givskov; Niels Høiby
Synthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice.
The Journal of antimicrobial chemotherapy 2004;53(6):1054-61.
2004: Tina S Boldt; Jan Sørensen; Ulrich Karlson; Søren Molin; Cayo Ramos
Combined use of different Gfp reporters for monitoring single-cell activities of a genetically modified PCB degrader in the rhizosphere of alfalfa.
FEMS microbiology ecology 2004;48(2):139-48.
2004: Christophe Beloin; Jaione Valle; Patricia Latour-Lambert; Philippe Faure; Mickaël Kzreminski; Damien BALESTRINO; Janus A J Haagensen; Søren Molin; Gérard Prensier; Brigitte Arbeille; Jean-Marc Ghigo
Global impact of mature biofilm lifestyle on Escherichia coli K-12 gene expression.
Molecular microbiology 2004;51(3):659-74.
2004: Kim Barken; Magdalena Gabig-Ciminska; Anders Holmgren; Søren Molin
Effect of unlabeled helper probes on detection of an RNA target by bead-based sandwich hybridization.
BioTechniques 2004;36(1):124-32.
2003: Adam C Martiny; Thomas Martini Jørgensen; Hans-Jørgen Albrechtsen; Erik Arvin; Søren Molin
Long-term succession of structure and diversity of a biofilm formed in a model drinking water distribution system.
Applied and environmental microbiology 2003;69(11):6899-907.
2003: Mikkel Klausen; Anders Aaes-Jørgensen; Søren Molin; Tim Tolker-Nielsen
Involvement of bacterial migration in the development of complex multicellular structures in Pseudomonas aeruginosa biofilms.
Molecular microbiology 2003;50(1):61-8.
2003: Morten Hentzer; Hong Wu; Jens Bo Andersen; Kathrin Riedel; Thomas Bovbjerg Rasmussen; Niels Bagge; Naresh Kumar; Mark A Schembri; Zhijun Song; Peter Kristoffersen; Mike Manefield; J William Costerton; Søren Molin; Leo Eberl; Peter D Steinberg; Staffan Kjelleberg; Niels Høiby; Michael Givskov
Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors.
The EMBO journal 2003;22(15):3803-15.
2003: Lars Ravn Flodgaard; Allan B Christensen; Søren Molin; Michael Givskov; Lone Gram
Influence of food preservation parameters and associated microbiota on production rate, profile and stability of acylated homoserine lactones from food-derived Enterobacteriaceae.
International journal of food microbiology 2003;84(2):145-56.
2003: Søren Molin; Tim Tolker-Nielsen
Gene transfer occurs with enhanced efficiency in biofilms and induces enhanced stabilisation of the biofilm structure.
Current opinion in biotechnology 2003;14(3):255-61.
2003: Mikkel Klausen; Arne Heydorn; Paula Ragas; Lotte Lambertsen; Anders Aaes-Jørgensen; Søren Molin; Tim Tolker-Nielsen
Biofilm formation by Pseudomonas aeruginosa wild type, flagella and type IV pili mutants.
Molecular microbiology 2003;48(6):1511-24.
2003: Tine Rask Licht; Carsten Struve; Bjarke Bak Christensen; RL Poulsen; Søren Molin; Karen A Krogfelt
Evidence of increased spread and establishment of plasmid RP4 in the intestine under sub-inhibitory tetracycline concentrations.
FEMS microbiology ecology 2003;44(2):217-23.
2003: Andreas Reisner; Janus A J Haagensen; Mark A Schembri; Ellen L Zechner; Søren Molin
Development and maturation of Escherichia coli K-12 biofilms.
Molecular microbiology 2003;48(4):933-46.
2003: Allan B Christensen; Kathrin Riedel; Leo Eberl; Lars Ravn Flodgaard; Søren Molin; Lone Gram; Michael Givskov
Quorum-sensing-directed protein expression in Serratia proteamaculans B5a.
Microbiology (Reading, England) 2003;149(Pt 2):471-83.
2003: Jens Bo Andersen; Birgit Koch; Tommy Harder Nielsen; Dan Sørensen; Michael Hansen; Ole Nybroe; Carsten Christophersen; Jan Sørensen; Søren Molin; Michael Givskov
Surface motility in Pseudomonas sp. DSS73 is required for efficient biological containment of the root-pathogenic microfungi Rhizoctonia solani and Pythium ultimum.
Microbiology (Reading, England) 2003;149(Pt 1):37-46.
2002: Anette Steidle; Marie Allesen-Holm; Kathrin Riedel; Gabriele Berg; Michael Givskov; Søren Molin; Leo Eberl
Identification and characterization of an N-acylhomoserine lactone-dependent quorum-sensing system in Pseudomonas putida strain IsoF.
Applied and environmental microbiology 2002;68(12):6371-82.
2002: Janus A J Haagensen; S K Hansen; T Johansen; Søren Molin
In situ detection of horizontal transfer of mobile genetic elements.
FEMS microbiology ecology 2002;42(2):261-8.
2002: Andreas Reisner; Søren Molin; Ellen L Zechner
Recombinogenic engineering of conjugative plasmids with fluorescent marker cassettes.
FEMS microbiology ecology 2002;42(2):251-9.
2002: Birgit Huber; Kathrin Riedel; Manuela Köthe; Michael Givskov; Søren Molin; Leo Eberl
Genetic analysis of functions involved in the late stages of biofilm development in Burkholderia cepacia H111.
Molecular microbiology 2002;46(2):411-26.
2002: Birgit Koch; Tommy Harder Nielsen; Dan Sørensen; Jens Bo Andersen; Carsten Christophersen; Søren Molin; Michael Givskov; Jan Sørensen; Ole Nybroe
Lipopeptide production in Pseudomonas sp. strain DSS73 is regulated by components of sugar beet seed exudate via the Gac two-component regulatory system.
Applied and environmental microbiology 2002;68(9):4509-16.
2002: Bjarke Bak Christensen; Janus A J Haagensen; Arne Heydorn; Søren Molin
Metabolic commensalism and competition in a two-species microbial consortium.
Applied and environmental microbiology 2002;68(5):2495-502.
2002: Arne Heydorn; Bjarne K Ersbøll; Junichi Kato; Morten Hentzer; Matthew R Parsek; Tim Tolker-Nielsen; Michael Givskov; Søren Molin
Statistical analysis of Pseudomonas aeruginosa biofilm development: impact of mutations in genes involved in twitching motility, cell-to-cell signaling, and stationary-phase sigma factor expression.
Applied and environmental microbiology 2002;68(4):2008-17.
2002: Morten Hentzer; Kathrin Riedel; Thomas Bovbjerg Rasmussen; Arne Heydorn; Jens Bo Andersen; Matthew R Parsek; Scott A Rice; Leo Eberl; Søren Molin; Niels Høiby; Staffan Kjelleberg; Michael Givskov
Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound.
Microbiology (Reading, England) 2002;148(Pt 1):87-102.
2001: Kathrin Riedel; Morten Hentzer; O Geisenberger; Birgit Huber; Anette Steidle; H Wu; Niels Høiby; Michael Givskov; Søren Molin; Leo Eberl
N-acylhomoserine-lactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms.
Microbiology (Reading, England) 2001;147(Pt 12):3249-62.
2001: Birgit Huber; Kathrin Riedel; Morten Hentzer; Arne Heydorn; Astrid Gotschlich; Michael Givskov; Søren Molin; Leo Eberl
The cep quorum-sensing system of Burkholderia cepacia H111 controls biofilm formation and swarming motility.
Microbiology (Reading, England) 2001;147(Pt 9):2517-28.
2001: Morten Hentzer; Gail M Teitzel; G J Balzer; Arne Heydorn; Søren Molin; Michael Givskov; Matthew R Parsek
Alginate overproduction affects Pseudomonas aeruginosa biofilm structure and function.
Journal of bacteriology 2001;183(18):5395-401.
2001: MC Hansen; A K Nielsen; Søren Molin; Karin Hammer; Mogens Kilstrup
Changes in rRNA levels during stress invalidates results from mRNA blotting: fluorescence in situ rRNA hybridization permits renormalization for estimation of cellular mRNA levels.
Journal of bacteriology 2001;183(16):4747-51.
2001: MC Hansen; Robert J Palmer; C Udsen; D C White; Søren Molin
Assessment of GFP fluorescence in cells of Streptococcus gordonii under conditions of low pH and low oxygen concentration.
Microbiology (Reading, England) 2001;147(Pt 5):1383-91.
2001: Lars Ravn; Allan B Christensen; Søren Molin; Michael Givskov; Lone Gram
Methods for detecting acylated homoserine lactones produced by Gram-negative bacteria and their application in studies of AHL-production kinetics.
Journal of microbiological methods 2001;44(3):239-51.
2001: Wen-Tso Liu; AT Nielsen; J H Wu; C S Tsai; Y Matsuo; Søren Molin
In situ identification of polyphosphate- and polyhydroxyalkanoate-accumulating traits for microbial populations in a biological phosphorus removal process.
Environmental microbiology 2001;3(2):110-22.
2001: Jens Bo Andersen; Arne Heydorn; Morten Hentzer; Leo Eberl; O Geisenberger; Bjarke Bak Christensen; Søren Molin; Michael Givskov
gfp-based N-acyl homoserine-lactone sensor systems for detection of bacterial communication.
Applied and environmental microbiology 2001;67(2):575-85.
2001: Camilla U Rang; T Midtvedt; Søren Molin; Lin Chao
Chemostat modeling of Escherichia coli persistence in conventionalized mono-associated and streptomycin-treated mice.
Canadian journal of microbiology 2001;47(1):86-90.
2001: C Ramos; Tine Rask Licht; Claus Sternberg; Karen A Krogfelt; Søren Molin
Monitoring bacterial growth activity in biofilms from laboratory flow chambers, plant rhizosphere, and animal intestine.
Methods in enzymology 2001;337():21-42.
2000: Kristian Kjaergaard; Mark A Schembri; C Ramos; Søren Molin; Per Klemm
Antigen 43 facilitates formation of multispecies biofilms.
Environmental microbiology 2000;2(6):695-702.
2000: Tim Tolker-Nielsen; U C Brinch; Paula Ragas; Jens Bo Andersen; Carsten S Jacobsen; Søren Molin
Development and dynamics of Pseudomonas sp. biofilms.
Journal of bacteriology 2000;182(22):6482-9.
2000: H Wu; Z Song; Morten Hentzer; Jens Bo Andersen; Arne Heydorn; Kalai Mathee; Claus Moser; Leo Eberl; Søren Molin; Niels Høiby; Michael Givskov
Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa.
Microbiology (Reading, England) 2000;146 ( Pt 10)():2481-93.
2000: Arne Heydorn; Bjarne K Ersbøll; Morten Hentzer; Matthew R Parsek; Michael Givskov; Søren Molin
Experimental reproducibility in flow-chamber biofilms.
Microbiology (Reading, England) 2000;146 ( Pt 10)():2409-15.
2000: Arne Heydorn; AT Nielsen; Morten Hentzer; Claus Sternberg; Michael Givskov; Bjarne K Ersbøll; Søren Molin
Quantification of biofilm structures by the novel computer program COMSTAT.
Microbiology (Reading, England) 2000;146 ( Pt 10)():2395-407.
2000: Leo Eberl; Aldo Ammendola; Michael Rothballer; Michael Givskov; Claus Sternberg; Mogens Kilstrup; Karl-Heinz Schleifer; Søren Molin
Inactivation of gltB abolishes expression of the assimilatory nitrate reductase gene (nasB) in Pseudomonas putida KT2442.
Journal of bacteriology 2000;182(12):3368-76.
2000: M Lange; Tim Tolker-Nielsen; Søren Molin; Birgitte K Ahring
In situ reverse transcription-PCR for monitoring gene expression in individual Methanosarcina mazei S-6 cells.
Applied and environmental microbiology 2000;66(5):1796-800.
2000: Tim Tolker-Nielsen; Allan B Christensen; K Holmstrøm; Leo Eberl; Thomas Bovbjerg Rasmussen; Claus Sternberg; Arne Heydorn; Søren Molin; Michael Givskov
Assessment of flhDC mRNA levels in Serratia liquefaciens swarm cells.
Journal of bacteriology 2000;182(10):2680-6.
2000: AT Nielsen; Tim Tolker-Nielsen; Kim Barken; Søren Molin
Role of commensal relationships on the spatial structure of a surface-attached microbial consortium.
Environmental microbiology 2000;2(1):59-68.
2000: Douglas E Caldwell; Rita R Colwell; S Harayama; Staffan Kjelleberg; Michael Givskov; Søren Molin; AT Nielsen; Arne Heydorn; Tim Tolker-Nielsen; Claus Sternberg; K Nealson; N R Pace; P Rainey; E Stackebrandt; B J Tindall; David A Stahl
Crystal ball: leading scientists in the field of environmental microbiology consider the technical and conceptual developments that they believe will drive innovative research during the first years of the new millennium.
Environmental microbiology 2000;2(1):3-10.
2000: C Ramos; Lars Mølbak; Søren Molin
Bacterial activity in the rhizosphere analyzed at the single-cell level by monitoring ribosome contents and synthesis rates.
Applied and environmental microbiology 2000;66(2):801-9.
1999: Søren Molin; Michael Givskov
Application of molecular tools for in situ monitoring of bacterial growth activity.
Environmental microbiology 1999;1(5):383-91.
1999: Tine Rask Licht; Bjarke Bak Christensen; Karen A Krogfelt; Søren Molin
Plasmid transfer in the animal intestine and other dynamic bacterial populations: the role of community structure and environment.
Microbiology (Reading, England) 1999;145 ( Pt 9)():2615-22.
1999: Claus Sternberg; Bjarke Bak Christensen; T Johansen; A Toftgaard Nielsen; Jens Bo Andersen; Michael Givskov; Søren Molin
Distribution of bacterial growth activity in flow-chamber biofilms.
Applied and environmental microbiology 1999;65(9):4108-17.
1999: Lone Gram; Allan B Christensen; Lars Ravn; Søren Molin; Michael Givskov
Production of acylated homoserine lactones by psychrotrophic members of the Enterobacteriaceae isolated from foods.
Applied and environmental microbiology 1999;65(8):3458-63.
1999: Kalai Mathee; Oana Ciofu; Claus Sternberg; PW Lindum; Joan I A Campbell; P Jensen; A H Johnsen; Michael Givskov; Dennis Ohman; Søren Molin; Niels Høiby; Arsalan Kharazmi
Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung.
Microbiology (Reading, England) 1999;145 ( Pt 6)():1349-57.
1999: O Geisenberger; Aldo Ammendola; Bjarke Bak Christensen; Søren Molin; Karl-Heinz Schleifer; Leo Eberl
Monitoring the conjugal transfer of plasmid RP4 in activated sludge and in situ identification of the transconjugants.
FEMS microbiology letters 1999;174(1):9-17.
1999: Camilla U Rang; Tine Rask Licht; T Midtvedt; P L Conway; Lin Chao; Karen A Krogfelt; Paul S Cohen; Søren Molin
Estimation of growth rates of Escherichia coli BJ4 in streptomycin-treated and previously germfree mice by in situ rRNA hybridization.
Clinical and diagnostic laboratory immunology 1999;6(3):434-6.
1999: K Hølmstrom; Tim Tolker-Nielsen; Søren Molin
Physiological states of individual Salmonella typhimurium cells monitored by in situ reverse transcription-PCR.
Journal of bacteriology 1999;181(6):1733-8.
1999: Leo Eberl; Søren Molin; Michael Givskov
Surface motility of serratia liquefaciens MG1.
Journal of bacteriology 1999;181(6):1703-12.
1999: AT Nielsen; Wen-Tso Liu; C Filipe; L Grady; Søren Molin; David A Stahl
Identification of a novel group of bacteria in sludge from a deteriorated biological phosphorus removal reactor.
Applied and environmental microbiology 1999;65(3):1251-8.
1999: Tine Rask Licht; Tim Tolker-Nielsen; K Holmstrøm; Karen A Krogfelt; Søren Molin
Inhibition of Escherichia coli precursor-16S rRNA processing by mouse intestinal contents.
Environmental microbiology 1999;1(1):23-32.
1999: Bjarke Bak Christensen; Claus Sternberg; Jens Bo Andersen; Robert J Palmer; AT Nielsen; Michael Givskov; Søren Molin
Molecular tools for study of biofilm physiology.
Methods in enzymology 1999;310():20-42.
1998: PW Lindum; Uffe Anthoni; Carsten Christophersen; Leo Eberl; Søren Molin; Michael Givskov
N-Acyl-L-homoserine lactone autoinducers control production of an extracellular lipopeptide biosurfactant required for swarming motility of Serratia liquefaciens MG1.
Journal of bacteriology 1998;180(23):6384-8.
1998: M I Ramos-González; Søren Molin
Cloning, sequencing, and phenotypic characterization of the rpoS gene from Pseudomonas putida KT2440.
Journal of bacteriology 1998;180(13):3421-31.
1998: Bjarke Bak Christensen; Claus Sternberg; Jens Bo Andersen; Leo Eberl; S Moller; Michael Givskov; Søren Molin
Establishment of new genetic traits in a microbial biofilm community.
Applied and environmental microbiology 1998;64(6):2247-55.
1998: Jens Bo Andersen; Claus Sternberg; LK Poulsen; S P Bjorn; Michael Givskov; Søren Molin
New unstable variants of green fluorescent protein for studies of transient gene expression in bacteria.
Applied and environmental microbiology 1998;64(6):2240-6.
1998: B Normander; Bjarke Bak Christensen; Søren Molin; Niels Kroer
Effect of bacterial distribution and activity on conjugal gene transfer on the phylloplane of the bush bean (Phaseolus vulgaris).
Applied and environmental microbiology 1998;64(5):1902-9.
1998: Tim Tolker-Nielsen; K Holmstrøm; L Boe; Søren Molin
Non-genetic population heterogeneity studied by in situ polymerase chain reaction.
Molecular microbiology 1998;27(6):1099-105.
1998: S Møller; Claus Sternberg; Jens Bo Andersen; Bjarke Bak Christensen; J L Ramos; Michael Givskov; Søren Molin
In situ gene expression in mixed-culture biofilms: evidence of metabolic interactions between community members.
Applied and environmental microbiology 1998;64(2):721-32.
1998: Michael Givskov; Jörgen Östling; Leo Eberl; PW Lindum; Allan B Christensen; G Christiansen; Søren Molin; Staffan Kjelleberg
Two separate regulatory systems participate in control of swarming motility of Serratia liquefaciens MG1.
Journal of bacteriology 1998;180(3):742-5.
1997: Camilla U Rang; R Mikkola; Søren Molin; P L Conway
Ribosomal efficiency and growth rates of freshly isolated Escherichia coli strains originating from the gastrointestinal tract.
FEBS letters 1997;418(1-2):27-9.
1997: Tim Tolker-Nielsen; K Holmstrøm; Søren Molin
Visualization of specific gene expression in individual Salmonella typhimurium cells by in situ PCR.
Applied and environmental microbiology 1997;63(11):4196-203.
1997: LK Poulsen; H M Dalton; M L Angles; K C Marshall; Søren Molin; AE Goodman
Simultaneous determination of gene expression and bacterial identity in single cells in defined mixtures of pure cultures.
Applied and environmental microbiology 1997;63(9):3698-702.
1997: A R Pedersen; S Møller; Søren Molin; Erik Arvin
Activity of Toluene-degrading Pseudomonas putida in the early growth phase of a biofilm for waste gas treatment.
Biotechnology and bioengineering 1997;54(2):131-41.
1997: Tim Tolker-Nielsen; M H Larsen; H Kyed; Søren Molin
Effects of stress treatments on the detection of Salmonella typhimurium by in situ hybridization.
International journal of food microbiology 1997;35(3):251-8.
1997: Claus Sternberg; Leo Eberl; LK Poulsen; Søren Molin
Detection of bioluminescence from individual bacterial cells: a comparison of two different low-light imaging systems.
Journal of bioluminescence and chemiluminescence 1997;12(1):7-13.
1996: S Møller; A R Pedersen; LK Poulsen; Erik Arvin; Søren Molin
Activity and three-dimensional distribution of toluene-degrading Pseudomonas putida in a multispecies biofilm assessed by quantitative in situ hybridization and scanning confocal laser microscopy.
Applied and environmental microbiology 1996;62(12):4632-40.
1996: Michael Givskov; Rocky de Nys; Mike Manefield; L Gram; R Maximilien; Leo Eberl; Søren Molin; Peter D Steinberg; Staffan Kjelleberg
Eukaryotic interference with homoserine lactone-mediated prokaryotic signalling.
Journal of bacteriology 1996;178(22):6618-22.
1996: Tim Tolker-Nielsen; Søren Molin
Role of ribosome degradation in the death of heat-stressed Salmonella typhimurium.
FEMS microbiology letters 1996;142(2-3):155-60.
1996: Tine Rask Licht; Karen A Krogfelt; Paul S Cohen; LK Poulsen; J Urbance; Søren Molin
Role of lipopolysaccharide in colonization of the mouse intestine by Salmonella typhimurium studied by in situ hybridization.
Infection and immunity 1996;64(9):3811-7.
1996: Leo Eberl; MK Winson; Claus Sternberg; GS Stewart; G Christiansen; Siri Ram Chhabra; Barrie W Bycroft; P Williams; Søren Molin; Michael Givskov
Involvement of N-acyl-L-hormoserine lactone autoinducers in controlling the multicellular behaviour of Serratia liquefaciens.
Molecular microbiology 1996;20(1):127-36.
1996: Karen A Krogfelt; Tine Rask Licht; Søren Molin
Lipopolysaccharide's role in the association of Salmonella cells to the mouse intestine studied by ribosomal in situ hybridization.
Advances in experimental medicine and biology 1996;408():123-8.
1996: Bjarke Bak Christensen; Claus Sternberg; Søren Molin
Bacterial plasmid conjugation on semi-solid surfaces monitored with the green fluorescent protein (GFP) from Aequorea victoria as a marker.
Gene 1996;173(1 Spec No):59-65.
1996: Leo Eberl; G Christiansen; Søren Molin; Michael Givskov
Differentiation of Serratia liquefaciens into swarm cells is controlled by the expression of the flhD master operon.
Journal of bacteriology 1996;178(2):554-9.
1995: L S van Overbeek; Leo Eberl; Michael Givskov; Søren Molin; J D van Elsas
Survival of, and induced stress resistance in, carbon-starved Pseudomonas fluorescens cells residing in soil.
Applied and environmental microbiology 1995;61(12):4202-8.
1995: LK Poulsen; Tine Rask Licht; Camilla U Rang; Karen A Krogfelt; Søren Molin
Physiological state of Escherichia coli BJ4 growing in the large intestines of streptomycin-treated mice.
Journal of bacteriology 1995;177(20):5840-5.
1995: Michael Givskov; Leo Eberl; G Christiansen; M J Benedik; Søren Molin
Induction of phospholipase- and flagellar synthesis in Serratia liquefaciens is controlled by expression of the flagellar master operon flhD.
Molecular microbiology 1995;15(3):445-54.
1995: Per Klemm; L B Jensen; Søren Molin
A stochastic killing system for biological containment of Escherichia coli.
Applied and environmental microbiology 1995;61(2):481-6.
1995: C S Kristensen; Leo Eberl; J M Sanchez-Romero; Michael Givskov; Søren Molin; Víctor de Lorenzo
Site-specific deletions of chromosomally located DNA segments with the multimer resolution system of broad-host-range plasmid RP4.
Journal of bacteriology 1995;177(1):52-8.
1994: LK Poulsen; F Lan; C S Kristensen; P Hobolth; Søren Molin; Karen A Krogfelt
Spatial distribution of Escherichia coli in the mouse large intestine inferred from rRNA in situ hybridization.
Infection and immunity 1994;62(11):5191-4.
1994: Michael Givskov; Leo Eberl; Søren Molin
Responses to nutrient starvation in Pseudomonas putida KT2442: two-dimensional electrophoretic analysis of starvation- and stress-induced proteins.
Journal of bacteriology 1994;176(16):4816-24.
1994: Michael Givskov; Leo Eberl; S Møller; LK Poulsen; Søren Molin
Responses to nutrient starvation in Pseudomonas putida KT2442: analysis of general cross-protection, cell shape, and macromolecular content.
Journal of bacteriology 1994;176(1):7-14.
1993: L B Jensen; J L Ramos; Z Kaneva; Søren Molin
A substrate-dependent biological containment system for Pseudomonas putida based on the Escherichia coli gef gene.
Applied and environmental microbiology 1993;59(11):3713-7.
1993: Søren Molin
Environmental potential of suicide genes.
Current opinion in biotechnology 1993;4(3):299-305.
1993: Michael Givskov; Søren Molin
Secretion of Serratia liquefaciens phospholipase from Escherichia coli.
Molecular microbiology 1993;8(2):229-42.
1993: Søren Molin; L Boe; L B Jensen; C S Kristensen; Michael Givskov; J L Ramos; Asim K Bej
Suicidal genetic elements and their use in biological containment of bacteria.
Annual review of microbiology 1993;47():139-66.
1992: Michael Givskov; Søren Molin
Expression of extracellular phospholipase from Serratia liquefaciens is growth-phase-dependent, catabolite-repressed and regulated by anaerobiosis.
Molecular microbiology 1992;6(10):1363-74.
1992: L K Poulsen; N W Larsen; Søren Molin; P Andersson
Analysis of an Escherichia coli mutant strain resistant to the cell-killing function encoded by the gef gene family.
Molecular microbiology 1992;6(7):895-905.
1992: Søren Molin
Designing microbes for release into the environment.
Science progress 1992;76(300 Pt 2):139-48.
1991: L K Poulsen; A Refn; Søren Molin; P Andersson
The gef gene from Escherichia coli is regulated at the level of translation.
Molecular microbiology 1991;5(7):1639-48.
1991: L K Poulsen; A Refn; Søren Molin; P Andersson
Topographic analysis of the toxic Gef protein from Escherichia coli.
Molecular microbiology 1991;5(7):1627-37.
1991: A Contreras; Søren Molin; Juan L Ramos
Conditional-suicide containment system for bacteria which mineralize aromatics.
Applied and environmental microbiology 1991;57(5):1504-8.
1988: Michael Givskov; L Olsen; Søren Molin
Cloning and expression in Escherichia coli of the gene for extracellular phospholipase A1 from Serratia liquefaciens.
Journal of bacteriology 1988;170(12):5855-62.
1987: L Boe; Kenn Gerdes; Søren Molin
Effects of genes exerting growth inhibition and plasmid stability on plasmid maintenance.
Journal of bacteriology 1987;169(10):4646-50.
1987: P B Rasmussen; Kenn Gerdes; Søren Molin
Genetic analysis of the parB+ locus of plasmid R1.
Molecular & general genetics : MGG 1987;209(1):122-8.
1987: Michael Givskov; P Stougaard; J Light; Søren Molin
Identification and characterization of mutations responsible for a runaway replication phenotype of plasmid R1.
Gene 1987;57(2-3):203-11.
1986: Kenn Gerdes; F W Bech; S T Jørgensen; A Løbner-Olesen; P B Rasmussen; Tove Atlung; L Boe; O Karlstrom; Søren Molin; K von Meyenburg
Mechanism of postsegregational killing by the hok gene product of the parB system of plasmid R1 and its homology with the relF gene product of the E. coli relB operon.
The EMBO journal 1986;5(8):2023-9.
1986: E Riise; Søren Molin
Purification and characterization of the CopB replication control protein, and precise mapping of its target site in the R1 plasmid.
Plasmid 1986;15(3):163-71.
1986: Kenn Gerdes; P B Rasmussen; Søren Molin
Unique type of plasmid maintenance function: postsegregational killing of plasmid-free cells.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(10):3116-20.
1985: J Light; E Riise; Søren Molin
Transcription and its regulation in the basic replicon region of plasmid R1.
Molecular & general genetics : MGG 1985;198(3):503-8.
1984: K Nordström; Søren Molin; J Light
Control of replication of bacterial plasmids: genetics, molecular biology, and physiology of the plasmid R1 system.
Plasmid 1984;12(2):71-90.
1983: J Light; Søren Molin
Post-transcriptional control of expression of the repA gene of plasmid R1 mediated by a small RNA molecule.
The EMBO journal 1983;2(1):93-8.
1982: E Riise; P Stougaard; B Bindslev; K Nordström; Søren Molin
Molecular cloning and functional characterization of a copy number control gene (copB) of plasmid R1.
Journal of bacteriology 1982;151(3):1136-45.
1982: P Stougaard; J Light; Søren Molin
Convergent transcription interferes with expression of the copy number control gene, copA, from plasmid R1.
The EMBO journal 1982;1(3):323-8.
1981: P Stougaard; Søren Molin; K Nordström
RNAs involved in copy-number control and incompatibility of plasmid R1.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(10):6008-12.
1981: Søren Molin; P Stougaard; J Light; M Nordström; K Nordström
Isolation and characterization of new copy mutants of plasmid R1, and identification of a polypeptide involved in copy number control.
Molecular & general genetics : MGG 1981;181(1):123-30.
1981: P Stougaard; Søren Molin; K Nordström; F G Hansen
The nucleotide sequence of the replication control region of the resistance plasmid R1drd-19.
Molecular & general genetics : MGG 1981;181(1):116-22.