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Lennart Möller

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Chemicals & Drugs

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Clara Ersson; Magdalena Ferlinska; Lykke Forchhammer; Roger Godschalk; Jennifer A Higgins; George D D Jones; Mahsa Karbaschi; Blanca Laffon; Steffen Loft; Adela López de Cerain; Giuseppe Matullo; Vilas Mistry; Peter Møller; Kirsty Nelson-Smith; David H Phillips; Marisa Porrini; Patrizia Riso; Michael Routledge; Osman Sozeri; Maciej Stepnik; João Paulo Teixeira; Vanessa Valdiglesias; Frederik-Jan van Schooten; Alessandra Allione; Amaia Azqueta; Andrew R Collins; Marcus S Cooke; Laura-Ana Corcuera; Solange Costa; Lennart Möller
An ECVAG inter-laboratory validation study of the comet assay: inter-laboratory and intra-laboratory variations of DNA strand breaks and FPG-sensitive sites in human mononuclear cells.
Ylva Rodhe; Royne Thorman; Therese Woodhill; Lennart Möller; Britta Hylander
The effect of sea buckthorn supplement on oral health, inflammation, and DNA damage in hemodialysis patients: a double-blinded, randomized crossover study.
Pontus Cronholm; Karine Elihn; Jonas Hedberg; Hanna L Karlsson; Troy A Lowe; Inger Odnevall Wallinder; Lina Winnberg; Lennart Möller
Intracellular uptake and toxicity of Ag and CuO nanoparticles: a comparison between nanoparticles and their corresponding metal ions.

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2013: Clara Ersson; Magdalena Ferlinska; Lykke Forchhammer; Roger Godschalk; Jennifer A Higgins; George D D Jones; Mahsa Karbaschi; Blanca Laffon; Steffen Loft; Adela López de Cerain; Giuseppe Matullo; Vilas Mistry; Peter Møller; Kirsty Nelson-Smith; David H Phillips; Marisa Porrini; Patrizia Riso; Michael Routledge; Osman Sozeri; Maciej Stepnik; João Paulo Teixeira; Vanessa Valdiglesias; Frederik-Jan van Schooten; Alessandra Allione; Amaia Azqueta; Andrew R Collins; Marcus S Cooke; Laura-Ana Corcuera; Solange Costa; Lennart Möller
An ECVAG inter-laboratory validation study of the comet assay: inter-laboratory and intra-laboratory variations of DNA strand breaks and FPG-sensitive sites in human mononuclear cells.
Mutagenesis 2013;28(3):279-86.
2013: Ylva Rodhe; Royne Thorman; Therese Woodhill; Lennart Möller; Britta Hylander
The effect of sea buckthorn supplement on oral health, inflammation, and DNA damage in hemodialysis patients: a double-blinded, randomized crossover study.
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 2013;23(3):172-9.
2013: Pontus Cronholm; Karine Elihn; Jonas Hedberg; Hanna L Karlsson; Troy A Lowe; Inger Odnevall Wallinder; Lina Winnberg; Lennart Möller
Intracellular uptake and toxicity of Ag and CuO nanoparticles: a comparison between nanoparticles and their corresponding metal ions.
Small (Weinheim an der Bergstrasse, Germany) 2013;9(7):970-82.
2013: Karine Elihn; Hanna L Karlsson; Klara Midander; Pontus Cronholm; Inger Odnevall Wallinder; Lennart Möller
Cellular dose of partly soluble cu particle aerosols at the air-liquid interface using an in vitro lung cell exposure system.
Journal of aerosol medicine and pulmonary drug delivery 2013;26(2):84-93.
2012: J Shi; I Odnevall Wallinder; Y Hedberg; Hanna L Karlsson; M Lundin; Lennart Möller
Hemolytic properties of synthetic nano- and porous silica particles: the effect of surface properties and the protection by the plasma corona.
Acta biomaterialia 2012;8(9):3478-90.
2012: Therese Bergström; Clara Ersson; Jan Bergman; Lennart Möller
Vitamins at physiological levels cause oxidation to the DNA nucleoside deoxyguanosine and to DNA--alone or in synergism with metals.
Mutagenesis 2012;27(4):511-7.
2012: J Kain; Hanna L Karlsson; Lennart Möller
DNA damage induced by micro- and nanoparticles--interaction with FPG influences the detection of DNA oxidation in the comet assay.
Mutagenesis 2012;27(4):491-500.
2011: Clara Ersson; Lennart Möller
The effects on DNA migration of altering parameters in the comet assay protocol such as agarose density, electrophoresis conditions and durations of the enzyme or the alkaline treatments.
Mutagenesis 2011;26(6):689-95.
2011: Therese Bergström; Jan Bergman; Lennart Möller
Vitamin A and C compounds permitted in supplements differ in their abilities to affect cell viability, DNA and the DNA nucleoside deoxyguanosine.
Mutagenesis 2011;26(6):735-44.
2011: Clara Ersson; Lennart Möller; Ylva Rodhe; Royne Thorman; Britta Hylander
DNA damage in salivary gland tissue in patients with chronic kidney disease, measured by the comet assay.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2011;112(2):209-15.
2011: Pontus Cronholm; Klara Midander; Hanna L Karlsson; Karine Elihn; Inger Odnevall Wallinder; Lennart Möller
Effect of sonication and serum proteins on copper release from copper nanoparticles and the toxicity towards lung epithelial cells.
Nanotoxicology 2011;5(2):269-81.
2010: Charlotte Jonsson; Per Stål; Urban Sjöqvist; Jan-Erik Akerlund; Robert Löfberg; Lennart Möller
DNA adducts in normal colonic mucosa from healthy controls and patients with colon polyps and colorectal carcinomas.
Mutagenesis 2010;25(5):499-504.
2010: Clara Johansson; Peter Møller; Lykke Forchhammer; Steffen Loft; Roger Godschalk; Sabine A S Langie; Stijn Lumeij; George D D Jones; Rachel W L Kwok; Amaya Azqueta; David H Phillips; Osman Sozeri; Michael Routledge; Alexander J Charlton; Patrizia Riso; Marisa Porrini; Alessandra Allione; Giuseppe Matullo; Jadwiga Palus; Maciej Stepnik; Andrew R Collins; Lennart Möller
An ECVAG trial on assessment of oxidative damage to DNA measured by the comet assay.
Mutagenesis 2010;25(2):125-32.
2009: Hanna L Karlsson; Johanna Gustafsson; Pontus Cronholm; Lennart Möller
Size-dependent toxicity of metal oxide particles--a comparison between nano- and micrometer size.
Toxicology letters 2009;188(2):112-8.
2009: Eszter Nagy; Michael G Cornelius; Lennart Möller
Accelerated (32)P-HPLC for bulky DNA adducts.
Mutagenesis 2009;24(2):183-9.
2008: Hanna L Karlsson; Pontus Cronholm; Johanna Gustafsson; Lennart Möller
Copper oxide nanoparticles are highly toxic: a comparison between metal oxide nanoparticles and carbon nanotubes.
Chemical research in toxicology 2008;21(9):1726-32.
2008: Clara Johansson; Elisabet Rytter; Jonas Nygren; Bengt Vessby; Samar Basu; Lennart Möller
Down-regulation of oxidative DNA lesions in human mononuclear cells after antioxidant supplementation correlates to increase of gamma-tocopherol.
International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition 2008;78(4-5):183-94.
2008: Hanna L Karlsson; Asa Holgersson; Lennart Möller
Mechanisms related to the genotoxicity of particles in the subway and from other sources.
Chemical research in toxicology 2008;21(3):726-31.
2007: Nuria Arranz; Ana I Haza; Almudena García; Lennart Möller; Joseph Rafter; Paloma Morales
Protective effects of organosulfur compounds towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2007;45(9):1662-9.
2007: Anya G Polischouk; Asa Holgersson; Dali Zong; Bo Stenerlöw; Hanna L Karlsson; Lennart Möller; Kristina Viktorsson; Rolf Lewensohn
The antipsychotic drug trifluoperazine inhibits DNA repair and sensitizes non small cell lung carcinoma cells to DNA double-strand break induced cell death.
Molecular cancer therapeutics 2007;6(8):2303-9.
2007: Eszter Nagy; Shuichi Adachi; Takeji Takamura-Enya; Magnus Zeisig; Lennart Möller
DNA adduct formation and oxidative stress from the carcinogenic urban air pollutant 3-nitrobenzanthrone and its isomer 2-nitrobenzanthrone, in vitro and in vivo.
Mutagenesis 2007;22(2):135-45.
2006: Nuria Arranz; Ana I Haza; Almudena García; Lennart Möller; Joseph Rafter; Paloma Morales
Protective effects of isothiocyanates towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay.
Journal of applied toxicology : JAT 2006;26(6):493-9.
2006: Hanna L Karlsson; Anders G Ljungman; John Lindbom; Lennart Möller
Comparison of genotoxic and inflammatory effects of particles generated by wood combustion, a road simulator and collected from street and subway.
Toxicology letters 2006;165(3):203-11.
2006: Nuria Arranz; Ana I Haza; Almudena García; Lennart Möller; Joseph Rafter; Paloma Morales
Protective effects of isothiocyanates towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay.
Journal of applied toxicology : JAT 2006;26(5):466-73.
2006: Eszter Nagy; Shuichi Adachi; Takeji Takamura-Enya; Magnus Zeisig; Lennart Möller
DNA damage and acute toxicity caused by the urban air pollutant 3-nitrobenzanthrone in rats: characterization of DNA adducts in eight different tissues and organs with synthesized standards.
Environmental and molecular mutagenesis 2006;47(7):541-52.
2006: Tim Hofer; Hanna L Karlsson; Lennart Möller
DNA oxidative damage and strand breaks in young healthy individuals: a gender difference and the role of life style factors.
Free radical research 2006;40(7):707-14.
2005: Eszter Nagy; Clara Johansson; Magnus Zeisig; Lennart Möller
Oxidative stress and DNA damage caused by the urban air pollutant 3-NBA and its isomer 2-NBA in human lung cells analyzed with three independent methods.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;827(1):94-103.
2005: Eszter Nagy; Magnus Zeisig; Ken Kawamura; Yoshiharu Hisamatsu; Akiko Sugeta; Shuichi Adachi; Lennart Möller
DNA adduct and tumor formations in rats after intratracheal administration of the urban air pollutant 3-nitrobenzanthrone.
Carcinogenesis 2005;26(10):1821-8.
2005: Grzegorz Nowak; Ulf G Norén; Annika Wernerson; Hanns-Ulrich Marschall; Lennart Möller; Bo-Göran Ericzon
Enteral donor pre-treatment with ursodeoxycholic acid protects the liver against ischaemia-reperfusion injury in rats.
Transplant international : official journal of the European Society for Organ Transplantation 2005;17(12):804-9.
2005: Hanna L Karlsson; Lennart Nilsson; Lennart Möller
Subway particles are more genotoxic than street particles and induce oxidative stress in cultured human lung cells.
Chemical research in toxicology 2005;18(1):19-23.
2004: Hanna L Karlsson; Jonas Nygren; Lennart Möller
Genotoxicity of airborne particulate matter: the role of cell-particle interaction and of substances with adduct-forming and oxidizing capacity.
Mutation research 2004;565(1):1-10.
2004: Linda L Magnusson; Jens Peter Bonde; Jørn Olsen; Lennart Möller; Kerstin Bingefors; Helena Wennborg
Paternal laboratory work and congenital malformations.
Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine 2004;46(8):761-7.
2004: Pawel Baranczewski; Lennart Möller
Relationship between content and activity of cytochrome P450 and induction of heterocyclic amine DNA adducts in human liver samples in vivo and in vitro.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(6):1071-8.
2004: Hanna L Eriksson; Magnus Zeisig; Lars-Gösta Ekström; Lennart Möller
32P-postlabeling of DNA adducts arising from complex mixtures: HPLC versus TLC separation applied to adducts from petroleum products.
Archives of toxicology 2004;78(3):174-81.
2004: Eszter Nagy; Ulf G Norén; Magnus Zeisig; Lars-Gösta Ekström; Lennart Möller
DNA adduct formation and physiological effects from crude oil distillate and its derived base oil in isolated, perfused rat liver.
Archives of toxicology 2004;78(2):114-21.
2003: Rainer Tuominen; Margareta Warholm; Lennart Möller; Agneta Rannug
Constitutive CYP1B1 mRNA expression in human blood mononuclear cells in relation to gender, genotype, and environmental factors.
Environmental research 2003;93(2):138-48.
2003: H Horie; Magnus Zeisig; K Hirayama; T Midtvedt; Lennart Möller; Joseph Rafter
Probiotic mixture decreases DNA adduct formation in colonic epithelium induced by the food mutagen 2-amino-9H-pyrido[2,3-b]indole in a human-flora associated mouse model.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 2003;12(2):101-7.
2003: Paweł Jałoszyński; Pawel Jaruga; Ryszard Oliński; Wieslawa Biczysko; Witold Szyfter; Eszter Nagy; Lennart Möller; Krzysztof Szyfter
Oxidative DNA base modifications and polycyclic aromatic hydrocarbon DNA adducts in squamous cell carcinoma of larynx.
Free radical research 2003;37(3):231-40.
2002: Rainer Tuominen; Pawel Baranczewski; Margareta Warholm; Lars Hagmar; Lennart Möller; Agneta Rannug
Susceptibility factors and DNA adducts in peripheral blood mononuclear cells of aluminium smelter workers exposed to polycyclic aromatic hydrocarbons.
Archives of toxicology 2002;76(3):178-86.
2002: Tim Hofer; Lennart Möller
Optimization of the workup procedure for the analysis of 8-oxo-7,8-dihydro-2'-deoxyguanosine with electrochemical detection.
Chemical research in toxicology 2002;15(3):426-32.
2001: L K Akkineni; Magnus Zeisig; Pawel Baranczewski; Lars-Gösta Ekström; Lennart Möller
Formation of DNA adducts from oil-derived products analyzed by 32P-HPLC.
Archives of toxicology 2001;74(11):720-31.
2000: Y Yang; William J Griffiths; Mirjam M Nordling; J Nygren; Lennart Möller; J Bergman; E Liepinsh; G Otting; J A Gustafsson; Joseph Rafter; Jan Sjövall
Ring opening of benzo[a]pyrene in the germ-free rat is a novel pathway for formation of potentially genotoxic metabolites.
Biochemistry 2000;39(50):15585-91.
2000: K Hirayama; Pawel Baranczewski; J E Akerlund; T Midtvedt; Lennart Möller; Joseph Rafter
Effects of human intestinal flora on mutagenicity of and DNA adduct formation from food and environmental mutagens.
Carcinogenesis 2000;21(11):2105-11.
2000: J Banaszewski; Zygmunt Szmeja; Witold Szyfter; Krzysztof Szyfter; Pawel Baranczewski; Lennart Möller
Analysis of aromatic DNA adducts in laryngeal biopsies.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2000;257(3):149-53.
1999: T Skarin; Björn Rozell; J Bergman; Rune Toftgård; Lennart Möller
Protection against 12-O-tetradecanoylphorbol-13-acetate induced skin-hyperplasia and tumor promotion, in a two-stage carcinogenesis mouse model, by the 2,3-dimethyl-6(2-dimethylaminoethyl)-6H-indolo-[2,3-b]quinoxaline analogue of ellipticine.
Chemico-biological interactions 1999;122(2):89-106.
1999: Magnus Zeisig; Tim Hofer; J Cadet; Lennart Möller
32P-postlabeling high-performance liquid chromatography (32P-HPLC) adapted for analysis of 8-hydroxy-2'-deoxyguanosine.
Carcinogenesis 1999;20(7):1241-5.
1999: X S Cui; Lennart C Eriksson; Lennart Möller
Formation and persistence of DNA adducts during and after a long-term administration of 2-nitrofluorene.
Mutation research 1999;442(1):9-18.
1998: Lennart Möller; Tim Hofer; Magnus Zeisig
Methodological considerations and factors affecting 8-hydroxy-2-deoxyguanosine analysis.
Free radical research 1998;29(6):511-24.
1998: Tim Hofer; Lennart Möller
Reduction of oxidation during the preparation of DNA and analysis of 8-hydroxy-2'-deoxyguanosine.
Chemical research in toxicology 1998;11(8):882-7.
1997: Lennart Möller; Tim Hofer
[32P]ATP mediates formation of 8-hydroxy-2'-deoxyguanosine from 2'-deoxyguanosine, a possible problem in the 32P-postlabeling assay.
Carcinogenesis 1997;18(12):2415-9.
1997: Magnus Zeisig; Lennart Möller
32P-Postlabeling high-performance liquid chromatographic improvements to characterize DNA adduct stereoisomers from benzo[a]pyrene and benzo[c]phenanthrene, and to separate DNA adducts from 7,12-dimethylbenz[a]anthracene.
Journal of chromatography. B, Biomedical sciences and applications 1997;691(2):341-50.
1996: P Wohlin; Magnus Zeisig; J A Gustafsson; Lennart Möller
32-P-HPLC analysis of DNA adducts formed in vitro and in vivo by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,4,8-trimethyl-3H-imidazo[4,5-f]quinoxaline, utilizing an improved adduct enrichment procedure.
Chemical research in toxicology 1996;9(6):1050-6.
1996: X S Cui; J Bergman; Lennart Möller
Preneoplastic lesions, DNA adduct formation and mutagenicity of 5-, 7- and 9-hydroxy-2-nitrofluorene, metabolites of the air pollutant 2-nitrofluorene.
Mutation research 1996;369(3-4):147-55.
1996: Lennart Möller; Ewa Grzybowska; Magnus Zeisig; B Cimander; Kari Hemminki; Mieczyslaw Chorazy
Seasonal variation of DNA adduct pattern in human lymphocytes analyzed by 32P-HPLC.
Carcinogenesis 1996;17(1):61-6.
1995: X S Cui; Ulla-Britta Torndal; Lennart C Eriksson; Lennart Möller
Early formation of DNA adducts compared with tumor formation in a long-term tumor study in rats after administration of 2-nitrofluorene.
Carcinogenesis 1995;16(9):2135-41.
1995: S Adachi; Magnus Zeisig; Lennart Möller
Improvements in the analytical method for 8-hydroxydeoxyguanosine in nuclear DNA.
Carcinogenesis 1995;16(2):253-8.
1995: P Stál; Rolf Hultcrantz; Lennart Möller; Lennart C Eriksson
The effects of dietary iron on initiation and promotion in chemical hepatocarcinogenesis.
Hepatology (Baltimore, Md.) 1995;21(2):521-8.
1995: Magnus Zeisig; Lennart Möller
32P-HPLC suitable for characterization of DNA adducts formed in vitro by polycyclic aromatic hydrocarbons and derivatives.
Carcinogenesis 1995;16(1):1-9.
1994: Lennart Möller
In vivo metabolism and genotoxic effects of nitrated polycyclic aromatic hydrocarbons.
Environmental health perspectives 1994;102 Suppl 4():139-46.
1994: Lennart Möller; D Schuetzle; H Autrup
Future research needs associated with the assessment of potential human health risks from exposure to toxic ambient air pollutants.
Environmental health perspectives 1994;102 Suppl 4():193-210.
1994: Lennart Möller; Magnus Zeisig; T Midtvedt; J A Gustafsson
Intestinal microflora enhances formation of DNA adducts following administration of 2-NF and 2-AAF.
Carcinogenesis 1994;15(5):857-61.
1993: Lennart Möller; X S Cui; Ulla-Britta Torndal; Lennart C Eriksson
Preneoplastic lesions and DNA adduct formation of the airborne genotoxic agents 2-nitrofluorene and 2,7-dinitrofluorene.
Carcinogenesis 1993;14(12):2627-32.
1993: Lennart Möller; I Lax; Lennart C Eriksson
Nitrated polycyclic aromatic hydrocarbons: a risk assessment for the urban citizen.
Environmental health perspectives 1993;101 Suppl 3():309-15.
1993: Lennart Möller; Magnus Zeisig; Rune Toftgård
Lack of initiating capacity of the genotoxic air pollutant 2-nitrofluorene in the mouse skin two-stage carcinogenesis system.
Carcinogenesis 1993;14(8):1723-5.
1993: Lennart Möller; Magnus Zeisig; Pavel Vodicka
Optimization of an HPLC method for analyses of 32P-postlabeled DNA adducts.
Carcinogenesis 1993;14(7):1343-8.
1993: Lennart Möller; Magnus Zeisig
DNA adduct formation after oral administration of 2-nitrofluorene and N-acetyl-2-aminofluorene, analyzed by 32P-TLC and 32P-HPLC.
Carcinogenesis 1993;14(1):53-9.
1990: S Törnquist; Lennart Möller; J Gabrielsson; J A Gustafsson; Rune Toftgård
2-Nitrofluorene metabolism in the rat lung. Pharmacokinetic and metabolic effects of beta-naphthoflavone treatment.
Carcinogenesis 1990;11(8):1249-54.
1989: Lennart Möller; Ulla-Britta Torndal; Lennart C Eriksson; J A Gustafsson
The air pollutant 2-nitrofluorene as initiator and promoter in a liver model for chemical carcinogenesis.
Carcinogenesis 1989;10(3):435-40.
1988: S Törnquist; M Sundin; Lennart Möller; J A Gustafsson; Rune Toftgård
Age dependent expression of cytochrome P-450b and metabolism of the potent carcinogen 2-nitrofluorene in the rat lung.
Carcinogenesis 1988;9(12):2209-14.
1988: B Beije; Lennart Möller
2-Nitrofluorene and related compounds: prevalence and biological effects.
Mutation research 1988;196(2):177-209.
1988: B Beije; Lennart Möller
Correlation between induction of unscheduled DNA synthesis in the liver and excretion of mutagenic metabolites in the urine of rats exposed to the carcinogenic air pollutant 2-nitrofluorene.
Carcinogenesis 1988;9(8):1465-70.
1988: Lennart Möller; M Corrie; T Midtvedt; Joseph Rafter; J A Gustafsson
The role of the intestinal microflora in the formation of mutagenic metabolites from the carcinogenic air pollutant 2-nitrofluorene.
Carcinogenesis 1988;9(5):823-30.
1987: Lennart Möller; S Törnquist; B Beije; Joseph Rafter; Rune Toftgård; J A Gustafsson
Metabolism of the carcinogenic air pollutant 2-nitrofluorene in the isolated perfused rat lung and liver.
Carcinogenesis 1987;8(12):1847-52.
1987: Lennart Möller; Joseph Rafter; J A Gustafsson
Metabolism of the carcinogenic air pollutant 2-nitrofluorene in the rat.
Carcinogenesis 1987;8(5):637-45.