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Michael Beckett

Research Profile

Anatomy

Physiology

Living Beings

Disorders

Procedures

Chemicals & Drugs

Phenomena

Radiation, Ionizing

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Publications

TOP 3
Hua Liang; Mark W Lingen; Ralph R Weichselbaum; Maryellyn Witt; Michael A Beckett; Byron Burnette; Steven Chmura; Thomas E Darga; Liufu Deng; Nicole Liadis; Yang-Xin Fu
Radiation-Induced Equilibrium Is a Balance between Tumor Cell Proliferation and T Cell-Mediated Killing.
Sean P Pitroda; Harold G Sutton; Randy F Sweis; Wei Zhang; Tong Zhou; Michael A Beckett; Thomas E Darga; Matthew Filippo; Joe G. N. Garcia; Sajid A Khan; Nikolai N Khodarev; Edwardine Labay; Hua Liang; Helena J Mauceri; Samantha Perakis; Ralph R Weichselbaum
Tumor endothelial inflammation predicts clinical outcome in diverse human cancers.
Alexander P Soneru; Ralph R Weichselbaum; Michael A Beckett; Raphael C Lee
Mg ATP and antioxidants augment the radioprotective effect of surfactant copolymers.

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All Publications

2013: Hua Liang; Mark W Lingen; Ralph R Weichselbaum; Maryellyn Witt; Michael A Beckett; Byron Burnette; Steven Chmura; Thomas E Darga; Liufu Deng; Nicole Liadis; Yang-Xin Fu
Radiation-Induced Equilibrium Is a Balance between Tumor Cell Proliferation and T Cell-Mediated Killing.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(11):5874-81.
2012: Sean P Pitroda; Harold G Sutton; Randy F Sweis; Wei Zhang; Tong Zhou; Michael A Beckett; Thomas E Darga; Matthew Filippo; Joe G. N. Garcia; Sajid A Khan; Nikolai N Khodarev; Edwardine Labay; Hua Liang; Helena J Mauceri; Samantha Perakis; Ralph R Weichselbaum
Tumor endothelial inflammation predicts clinical outcome in diverse human cancers.
PloS one 2012;7(10):e46104.
2011: Alexander P Soneru; Ralph R Weichselbaum; Michael A Beckett; Raphael C Lee
Mg ATP and antioxidants augment the radioprotective effect of surfactant copolymers.
Health physics 2011;101(6):731-8.
2011: Juan Camilo Barreto-Andrade; Michael A Beckett; Thomas E Darga; Elena V Efimova; Stephen J Kron; Helena J Mauceri; Mitchell C Posner; Harold G Sutton; Everett E Vokes; Ralph R Weichselbaum
Response of human prostate cancer cells and tumors to combining PARP inhibition with ionizing radiation.
Molecular cancer therapeutics 2011;10(7):1185-93.
2010: Yuru Meng; Helena J Mauceri; Nikolai N Khodarev; Thomas E Darga; Sean P Pitroda; Michael A Beckett; Donald W Kufe; Ralph R Weichselbaum
Ad.Egr-TNF and local ionizing radiation suppress metastases by interferon-beta-dependent activation of antigen-specific CD8+ T cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(5):912-20.
2010: Yuru Meng; Michael A Beckett; Hua Liang; Helena J Mauceri; Nico van Rooijen; Kenneth S Cohen; Ralph R Weichselbaum
Blockade of tumor necrosis factor alpha signaling in tumor-associated macrophages as a radiosensitizing strategy.
Cancer research 2010;70(4):1534-43.
2009: Sean P Pitroda; Nikolai N Khodarev; Michael A Beckett; Donald W Kufe; Ralph R Weichselbaum
MUC1-induced alterations in a lipid metabolic gene network predict response of human breast cancers to tamoxifen treatment.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(14):5837-41.
2009: Nikolai N Khodarev; Sean P Pitroda; Michael A Beckett; Dhara M MacDermed; Lei Huang; Donald W Kufe; Ralph R Weichselbaum
MUC1-induced transcriptional programs associated with tumorigenesis predict outcome in breast and lung cancer.
Cancer research 2009;69(7):2833-7.
2009: Helena J Mauceri; Michael A Beckett; H Liang; H G Sutton; S Pitroda; E Galka; E Efimova; Thomas E Darga; N N Khodarev; C Richter King; Mitchell C Posner; Samuel Hellman; Donald Kufe; Ralph R Weichselbaum
Translational strategies exploiting TNF-alpha that sensitize tumors to radiation therapy.
Cancer gene therapy 2009;16(4):373-81.
2009: Sean P Pitroda; Bassam T Wakim; Ravi F Sood; Mara G Beveridge; Michael A Beckett; Dhara M MacDermed; Ralph R Weichselbaum; Nikolai N Khodarev
STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect.
BMC medicine 2009;7():68.
2009: Nikolai N Khodarev; Paul Roach; Sean P Pitroda; Daniel W Golden; Mihir Bhayani; Michael Y Shao; Thomas E Darga; Mara G Beveridge; Ravi F Sood; Harold G Sutton; Michael A Beckett; Helena J Mauceri; Mitchell C Posner; Ralph R Weichselbaum
STAT1 pathway mediates amplification of metastatic potential and resistance to therapy.
PloS one 2009;4(6):e5821.
2007: Nikolai N Khodarev; Andy J Minn; Elena V Efimova; Thomas E Darga; Edwardine Labay; Michael A Beckett; Helena J Mauceri; Bernard Roizman; Ralph R Weichselbaum
Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells.
Cancer research 2007;67(19):9214-20.
2006: James Mezhir; Kerrington D Smith; Eric T Kimchi; James Park; Carlos A Lopez; Helena J Mauceri; Michael A Beckett; Samuel Hellman; Ralph R Weichselbaum; Mitchell C Posner
Establishment of a syngeneic model of hepatic colorectal oligometastases.
The Journal of surgical research 2006;136(2):288-93.
2005: Kevin T Murphy; Abdullah Wardak; Michael A Beckett; Carlos A Lopez; Neil Mehta; Eric T Kimchi; Rabih M Salloum; Nora T Jaskowiak; Mitchell C Posner; Tsuneya Ohno; Donald Kufe; Ralph R Weichselbaum; Helena J Mauceri
Forphenicinol enhances the antitumor effects of cyclophosphamide in a model of squamous cell carcinoma.
Cancer chemotherapy and pharmacology 2005;56(3):317-21.
2004: Carlos A Lopez; Eric T Kimchi; Helena J Mauceri; James Park; Neil Mehta; Kevin T Murphy; Michael A Beckett; Samuel Hellman; Mitchell C Posner; Donald Kufe; Ralph R Weichselbaum
Chemoinducible gene therapy: a strategy to enhance doxorubicin antitumor activity.
Molecular cancer therapeutics 2004;3(9):1167-75.
2004: Ben Greenebaum; Katie Blossfield; Jurgen Hannig; Cinthya S Carrillo; Michael A Beckett; Ralph R Weichselbaum; Raphael Lee
Poloxamer 188 prevents acute necrosis of adult skeletal muscle cells following high-dose irradiation.
Burns : journal of the International Society for Burn Injuries 2004;30(6):539-47.
2004: Carlos A Lopez; James Park; Helena J Mauceri; Michael A Beckett; Ralph R Weichselbaum; Mitchell C Posner
Control of gene therapy by MDR1 and EGR1 promoter sequences in transcriptional targeting by chemotherapy (Review).
International journal of oncology 2004;24(3):731-6.
2004: Nikolai N Khodarev; Michael A Beckett; Edwardine Labay; Thomas E Darga; Bernard Roizman; Ralph R Weichselbaum
STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(6):1714-9.
2004: Neelam Taneja; Mandel Davis; John Choy; Michael A Beckett; Rachana Singh; Stephen J Kron; Ralph R Weichselbaum
Histone H2AX phosphorylation as a predictor of radiosensitivity and target for radiotherapy.
The Journal of biological chemistry 2004;279(3):2273-80.
2002: Helena J Mauceri; Saraswathy Seetharam; Michael A Beckett; L Philip Schumm; Ann Koons; Vinay K Gupta; James Park; Abdullah Manan; John Y Lee; Anthony G Montag; Donald Kufe; Ralph R Weichselbaum
Angiostatin potentiates cyclophosphamide treatment of metastatic disease.
Cancer chemotherapy and pharmacology 2002;50(5):412-8.
2002: Helena J Mauceri; Saraswathy Seetharam; Michael A Beckett; John Y Lee; Vinay K Gupta; Stephen Gately; M Sharon Stack; Charles K Brown; Kirsten Swedberg; Donald Kufe; Ralph R Weichselbaum
Tumor production of angiostatin is enhanced after exposure to TNF-alpha.
International journal of cancer. Journal international du cancer 2002;97(4):410-5.
2002: Vinay K Gupta; Nora T Jaskowiak; Michael A Beckett; Helena J Mauceri; Jeremy Grunstein; Randall S Johnson; Douglas A Calvin; Edwardine Nodzenski; Marija Pejovic; Donald Kufe; Mitchell C Posner; Ralph R Weichselbaum
Vascular endothelial growth factor enhances endothelial cell survival and tumor radioresistance.
Cancer journal (Sudbury, Mass.) 2002;8(1):47-54.
2001: Nalin Gupta; Edwardine Nodzenski; Nikolai N Khodarev; Jianqing Yu; Leila Khorasani; Michael A Beckett; Donald Kufe; Ralph R Weichselbaum
Angiostatin effects on endothelial cells mediated by ceramide and RhoA.
EMBO reports 2001;2(6):536-40.
2000: Rabih M Salloum; Nora T Jaskowiak; Helena J Mauceri; Saraswathy Seetharam; Michael A Beckett; Ann Koons; DM Hari; Vinay K Gupta; C Reimer; Raghu Kalluri; Mitchell C Posner; Samuel Hellman; Donald Kufe; Ralph R Weichselbaum
NM-3, an isocoumarin, increases the antitumor effects of radiotherapy without toxicity.
Cancer research 2000;60(24):6958-63.
2000: Nadar N Hanna; Saraswathy Seetharam; Helena J Mauceri; Michael A Beckett; Nora T Jaskowiak; Rabih M Salloum; DM Hari; Mohanraj Dhanabal; Ramani Ramchandran; Raghu Kalluri; Vikas P Sukhatme; Donald Kufe; Ralph R Weichselbaum
Antitumor interaction of short-course endostatin and ionizing radiation.
Cancer journal (Sudbury, Mass.) 2000;6(5):287-93.
2000: Jurgen Hannig; Dongsheng Zhang; D J Canaday; Michael A Beckett; R Dean Astumian; Ralph R Weichselbaum; Raphael Lee
Surfactant sealing of membranes permeabilized by ionizing radiation.
Radiation research 2000;154(2):171-7.
2000: DM Hari; Michael A Beckett; Vikas P Sukhatme; Mohanraj Dhanabal; Edwardine Nodzenski; H Lu; Helena J Mauceri; Donald Kufe; Ralph R Weichselbaum
Angiostatin induces mitotic cell death of proliferating endothelial cells.
Molecular cell biology research communications : MCBRC 2000;3(5):277-82.
1999: M A Terry; Jurgen Hannig; C S Carrillo; Michael A Beckett; Ralph R Weichselbaum; Raphael Lee
Oxidative cell membrane alteration. Evidence for surfactant-mediated sealing.
Annals of the New York Academy of Sciences 1999;888():274-84.
1999: David Henry Gorski; Michael A Beckett; Nora T Jaskowiak; Douglas P Calvin; Helena J Mauceri; Rabih M Salloum; Saraswathy Seetharam; Ann Koons; DM Hari; Donald Kufe; Ralph R Weichselbaum
Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation.
Cancer research 1999;59(14):3374-8.
1999: Jurgen Hannig; J Yu; Michael A Beckett; R Weichselbaum; Raphael Lee
Poloxamine 1107 sealing of radiopermeabilized erythrocyte membranes.
International journal of radiation biology 1999;75(3):379-85.
1999: Helena J Mauceri; Nadar N Hanna; MJ Staba; Michael A Beckett; Donald Kufe; Ralph R Weichselbaum
Radiation-inducible gene therapy.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1999;322(2-3):225-8.
1998: David Henry Gorski; Helena J Mauceri; Rabih M Salloum; Stephen Gately; Samuel Hellman; Michael A Beckett; Vikas P Sukhatme; Gerald A Soff; Donald Kufe; Ralph R Weichselbaum
Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin.
Cancer research 1998;58(24):5686-9.
1998: Douglas K Bishop; US Ear; A Bhattacharyya; C Calderone; Michael A Beckett; Ralph R Weichselbaum; Akira Shinohara
Xrcc3 is required for assembly of Rad51 complexes in vivo.
The Journal of biological chemistry 1998;273(34):21482-8.
1998: Saraswathy Seetharam; Edwardine Nodzenski; Michael A Beckett; Ruth Heimann; A Cha; I Margulies; Ira Pastan; Donald Kufe; Ralph R Weichselbaum
Modulation of apoptotic response of a radiation-resistant human carcinoma by Pseudomonas exotoxin-chimeric protein.
Cancer research 1998;58(15):3215-20.
1998: Helena J Mauceri; Nadar N Hanna; Michael A Beckett; David Henry Gorski; MJ Staba; K A Stellato; K Bigelow; Ruth Heimann; Stephen Gately; Mohanraj Dhanabal; Gerald A Soff; Vikas P Sukhatme; Donald Kufe; Ralph R Weichselbaum
Combined effects of angiostatin and ionizing radiation in antitumour therapy.
Nature 1998;394(6690):287-91.
1997: Steven J Chmura; Helena J Mauceri; S Advani; Ruth Heimann; Michael A Beckett; Edwardine Nodzenski; J Quintans; Donald Kufe; Ralph R Weichselbaum
Decreasing the apoptotic threshold of tumor cells through protein kinase C inhibition and sphingomyelinase activation increases tumor killing by ionizing radiation.
Cancer research 1997;57(19):4340-7.
1997: Steven J Chmura; Edwardine Nodzenski; Michael A Beckett; Donald Kufe; J Quintans; Ralph R Weichselbaum
Loss of ceramide production confers resistance to radiation-induced apoptosis.
Cancer research 1997;57(7):1270-5.
1995: L P Seung; Helena J Mauceri; Michael A Beckett; Dennis E Hallahan; Samuel Hellman; Ralph R Weichselbaum
Genetic radiotherapy overcomes tumor resistance to cytotoxic agents.
Cancer research 1995;55(23):5561-5.
1995: Arno J Mundt; Azhar M. Awan; G S Sibley; M Simon; S J Rubin; Brian L Samuels; W Wong; Michael A Beckett; Srinivasan Vijayakumar; Ralph R Weichselbaum
Conservative surgery and adjuvant radiation therapy in the management of adult soft tissue sarcoma of the extremities: clinical and radiobiological results.
International journal of radiation oncology, biology, physics 1995;32(4):977-85.
1995: Ralph R Weichselbaum; Michael A Beckett; Everett E Vokes; D G Brachman; Daniel J Haraf; Dennis E Hallahan; Donald Kufe
Cellular and molecular mechanisms of radioresistance.
Cancer treatment and research 1995;74():131-40.
1994: Ralph R Weichselbaum; Dennis E Hallahan; Michael A Beckett; Helena J Mauceri; H Lee; Vikas P Sukhatme; Donald Kufe
Gene therapy targeted by radiation preferentially radiosensitizes tumor cells.
Cancer research 1994;54(16):4266-9.
1993: J M Cowan; Michael A Beckett; Ralph R Weichselbaum
Chromosome changes characterizing in vitro response to radiation in human squamous cell carcinoma lines.
Cancer research 1993;53(22):5542-7.
1993: D G Brachman; Michael A Beckett; D Graves; Daniel J Haraf; Everett E Vokes; Ralph R Weichselbaum
p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines.
Cancer research 1993;53(16):3667-9.
1993: L A Pekarek; Ralph R Weichselbaum; Michael A Beckett; James B Nachman; Hans Schreiber
Footprinting of individual tumors and their variants by constitutive cytokine expression patterns.
Cancer research 1993;53(9):1978-81.
1992: D G Brachman; D Graves; Everett E Vokes; Michael A Beckett; Daniel J Haraf; A Montag; E Dunphy; R Mick; D Yandell; Ralph R Weichselbaum
Occurrence of p53 gene deletions and human papilloma virus infection in human head and neck cancer.
Cancer research 1992;52(17):4832-6.
1992: Ralph R Weichselbaum; Michael A Beckett; Dennis E Hallahan; Donald Kufe; Everett E Vokes
Molecular targets to overcome radioresistance.
Seminars in oncology 1992;19(4 Suppl 11):14-20.
1992: J M Cowan; Michael A Beckett; S Ahmed-Swan; Ralph R Weichselbaum
Cytogenetic evidence of the multistep origin of head and neck squamous cell carcinomas.
Journal of the National Cancer Institute 1992;84(10):793-7.
1992: E J Dunphy; Michael A Beckett; L H Thompson; Ralph R Weichselbaum
Expression of the polymorphic human DNA repair gene XRCC1 does not correlate with radiosensitivity in the cells of human head and neck tumor cell lines.
Radiation research 1992;130(2):166-70.
1992: D R Jaffe; Y Montero-Puerner; Michael A Beckett; J M Cowan; Ralph R Weichselbaum; Alan M Diamond
Differential retention of tumor- and differentiation-suppressor functions in cells derived from a human squamous cell carcinoma.
Molecular carcinogenesis 1992;5(4):278-85.
1991: D G Brachman; Dennis E Hallahan; Michael A Beckett; D W Yandell; Ralph R Weichselbaum
p53 gene mutations and abnormal retinoblastoma protein in radiation-induced human sarcomas.
Cancer research 1991;51(23 Pt 1):6393-6.
1991: Dennis E Hallahan; S Virudachalam; Michael A Beckett; M L Sherman; Donald Kufe; Ralph R Weichselbaum
Mechanisms of X-ray-mediated protooncogene c-jun expression in radiation-induced human sarcoma cell lines.
International journal of radiation oncology, biology, physics 1991;21(6):1677-81.
1991: Jeffrey L Schwartz; R Mustafi; Michael A Beckett; E A Czyzewski; E Farhangi; David J Grdina; Jacob Rotmensch; Ralph R Weichselbaum
Radiation-induced DNA double-strand break frequencies in human squamous cell carcinoma cell lines of different radiation sensitivities.
International journal of radiation biology 1991;59(6):1341-52.
1991: B L Samuels; J L Murray; M B Cohen; Ahmad R Safa; B K Sinha; Alan J Townsend; Michael A Beckett; Ralph R Weichselbaum
Increased glutathione peroxidase activity in a human sarcoma cell line with inherent doxorubicin resistance.
Cancer research 1991;51(2):521-7.
1991: S J Rubin; Dennis E Hallahan; C R Ashman; D G Brachman; Michael A Beckett; S Virudachalam; D W Yandell; Ralph R Weichselbaum
Two prostate carcinoma cell lines demonstrate abnormalities in tumor suppressor genes.
Journal of surgical oncology 1991;46(1):31-6.
1990: J M Cowan; Michael A Beckett; N Tarbell; Ralph R Weichselbaum
Symmetrical chromosome rearrangements in cell lines established from human radiation-induced sarcomas.
Cancer genetics and cytogenetics 1990;50(1):125-37.
1990: J M Cowan; Michael A Beckett; N J Tarbell; Ralph R Weichselbaum
Monosomy 12p in a radiation-induced germ cell tumor.
Genes, chromosomes & cancer 1990;2(3):186-90.
1990: Ralph R Weichselbaum; Michael A Beckett; Srinivasan Vijayakumar; M A Simon; Azhar M. Awan; James B Nachman; WR Panje; M E Goldman; A G Tybor; W J Moran
Radiobiological characterization of head and neck and sarcoma cells derived from patients prior to radiotherapy.
International journal of radiation oncology, biology, physics 1990;19(2):313-9.
1990: Dennis E Hallahan; Michael A Beckett; Donald Kufe; Ralph R Weichselbaum
The interaction between recombinant human tumor necrosis factor and radiation in 13 human tumor cell lines.
International journal of radiation oncology, biology, physics 1990;19(1):69-74.
1990: Jeffrey L Schwartz; R Mustafi; Michael A Beckett; Ralph R Weichselbaum
Prediction of the radiation sensitivity of human squamous cell carcinoma cells using DNA filter elution.
Radiation research 1990;123(1):1-6.
1989: Dennis E Hallahan; David Spriggs; Michael A Beckett; Donald Kufe; Ralph R Weichselbaum
Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(24):10104-7.
1989: Ralph R Weichselbaum; Jacob Rotmensch; S Ahmed-Swan; Michael A Beckett
Radiobiological characterization of 53 human tumor cell lines.
International journal of radiation biology 1989;56(5):553-60.
1989: Ralph R Weichselbaum; E J Dunphy; Michael A Beckett; A G Tybor; W J Moran; M E Goldman; Everett E Vokes; WR Panje
Epidermal growth factor receptor gene amplification and expression in head and neck cancer cell lines.
Head & neck 1989;11(5):437-42.
1989: Ralph R Weichselbaum; Michael A Beckett; Srinivasan Vijayakumar; S Ahmed-Swan; A Dritschilo; J L Schwartz; W J Moran; M E Goldman; A G Tybor; Everett E Vokes
Radioresistant tumor cell lines derived from head and neck radiation failures.
Head & neck 1989;11(4):343-8.
1989: Ralph R Weichselbaum; Michael A Beckett; Alan M Diamond
An important step in radiation carcinogenesis may be inactivation of cellular genes.
International journal of radiation oncology, biology, physics 1989;16(1):277-82.
1988: Ralph R Weichselbaum; Michael A Beckett; M A Simon; C McCauley; Daniel J Haraf; Azhar M. Awan; Brian L Samuels; James B Nachman; A Dritschilo
In vitro radiobiological parameters of human sarcoma cell lines.
International journal of radiation oncology, biology, physics 1988;15(4):937-42.
1988: Jeffrey L Schwartz; Jacob Rotmensch; Michael A Beckett; D R Jaffe; M Toohill; S M Giovanazzi; J McIntosh; Ralph R Weichselbaum
X-ray and cis-diamminedichloroplatinum(II) cross-resistance in human tumor cell lines.
Cancer research 1988;48(18):5133-5.
1988: Ralph R Weichselbaum; Michael A Beckett; Jeffrey L Schwartz; A Dritschilo
Radioresistant tumor cells are present in head and neck carcinomas that recur after radiotherapy.
International journal of radiation oncology, biology, physics 1988;15(3):575-9.
1988: Michael A Beckett; Ralph R Weichselbaum
Southern analysis of human head and neck cancer cells for homologous sequences using yeast gamma repair genes.
Journal of surgical oncology 1988;38(4):257-60.
1988: S P Ackland; Richard L Schilsky; Michael A Beckett; Ralph R Weichselbaum
Synergistic cytotoxicity and DNA strand break formation by bromodeoxyuridine and bleomycin in human tumor cells.
Cancer research 1988;48(15):4244-9.
1988: Ralph R Weichselbaum; Michael A Beckett; W Dahlberg; A Dritschilo
Heterogeneity of radiation response of a parent human epidermoid carcinoma cell line and four clones.
International journal of radiation oncology, biology, physics 1988;14(5):907-12.
1988: Ralph R Weichselbaum; Michael A Beckett; Alan M Diamond
Some retinoblastomas, osteosarcomas, and soft tissue sarcomas may share a common etiology.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(7):2106-9.

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