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Paul Monahan

Research Profile

Chemicals & Drugs

Disorders

Procedures

Genetic Therapy

Living Beings

Physiology

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Gene Transfer Techniques

Genes & Molecular Sequences

Transgenes

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Publications

TOP 3
J Michael Soucie; Meera B Chitlur; Christine De Staercke; Ralph Gruppo; W Craig Hooper; Craig Kessler; Roshni Kulkarni; Marilyn J Manco-Johnson; Paul E Monahan; Jerry Powell; Meredith Pyle; Michael Recht; Brenda Riske; Hernan Sabio; Sean Trimble
Evidence for the continued transmission of parvovirus B19 in patients with bleeding disorders treated with plasma-derived factor concentrates.
Brian R Branchford; Paul E Monahan; Jorge Di Paola
New developments in the treatment of pediatric hemophilia and bleeding disorders.
Paul E Monahan; Rolf Ljung; Andrea S Doria; Victor Jiménez-Yuste
Optimizing joint function: new knowledge and novel tools and treatments.

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All Publications

2013: J Michael Soucie; Meera B Chitlur; Christine De Staercke; Ralph Gruppo; W Craig Hooper; Craig Kessler; Roshni Kulkarni; Marilyn J Manco-Johnson; Paul E Monahan; Jerry Powell; Meredith Pyle; Michael Recht; Brenda Riske; Hernan Sabio; Sean Trimble
Evidence for the continued transmission of parvovirus B19 in patients with bleeding disorders treated with plasma-derived factor concentrates.
Transfusion 2013;53(5):1143-4.
2013: Brian R Branchford; Paul E Monahan; Jorge Di Paola
New developments in the treatment of pediatric hemophilia and bleeding disorders.
Current opinion in pediatrics 2013;25(1):23-30.
2012: Paul E Monahan; Rolf Ljung; Andrea S Doria; Victor Jiménez-Yuste
Optimizing joint function: new knowledge and novel tools and treatments.
Haemophilia : the official journal of the World Federation of Hemophilia 2012;18 Suppl 5():17-26.
2011: Paul E Monahan; Brenda Riske; Judith R Baker; J Michael Soucie
Physical functioning in boys with hemophilia in the U.S.
American journal of preventive medicine 2011;41(6 Suppl 4):S360-8.
2010: Paul E Monahan
The expanding menagerie: animal models of hemophilia A.
Journal of thrombosis and haemostasis : JTH 2010;8(11):2469-71.
2010: Paul E Monahan; Clinton D Lothrop; Junjiang Sun; Matthew L Hirsch; Tal Kafri; Boris Kantor; Rita Sarkar; D Michael Tillson; Joseph R Elia; R Jude Samulski
Proteasome inhibitors enhance gene delivery by AAV virus vectors expressing large genomes in hemophilia mouse and dog models: a strategy for broad clinical application.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(11):1907-16.
2010: Paul E Monahan; R Liesner; S T Sullivan; M E Ramirez; P Kelly; D A Roth
Safety and efficacy of investigator-prescribed BeneFIX prophylaxis in children less than 6 years of age with severe haemophilia B.
Haemophilia : the official journal of the World Federation of Hemophilia 2010;16(3):460-8.
2010: Paul E Monahan; Junjiang Sun
Hemophilic synovitis: factor VII and the potential role of extravascular factor VIIa.
Thrombosis research 2010;125 Suppl 1():S63-6.
2009: Boris Kantor; Hong Ma; Jennifer Webster-Cyriaque; Paul E Monahan; Tal Kafri
Epigenetic activation of unintegrated HIV-1 genomes by gut-associated short chain fatty acids and its implications for HIV infection.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(44):18786-91.
2009: Tong Gui; A Reheman; H Ni; P L Gross; F Yin; Dougald M Monroe; Paul E Monahan; Darrel W Stafford
Abnormal hemostasis in a knock-in mouse carrying a variant of factor IX with impaired binding to collagen type IV.
Journal of thrombosis and haemostasis : JTH 2009;7(11):1843-51.
2009: Chengwen Li; Kevin Goudy; Matt Hirsch; Aravind Asokan; Yun Fan; Jeff Alexander; Junjiang Sun; Paul E Monahan; David Seiber; John Sidney; Alessandro Sette; Roland Tisch; Jeffrey Frelinger; R Jude Samulski
Cellular immune response to cryptic epitopes during therapeutic gene transfer.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(26):10770-4.
2008: Junjiang Sun; Narine Hakobyan; Leonard A Valentino; Brian L Feldman; R Jude Samulski; Paul E Monahan
Intraarticular factor IX protein or gene replacement protects against development of hemophilic synovitis in the absence of circulating factor IX.
Blood 2008;112(12):4532-41.
2008: Brent W Weston; Paul E Monahan
Familial deficiency of vitamin K-dependent clotting factors.
Haemophilia : the official journal of the World Federation of Hemophilia 2008;14(6):1209-13.
2008: Paul E Monahan
Factor IX: Insights from knock-out and genetically engineered mice.
Thrombosis and haemostasis 2008;100(4):563-75.
2008: Zhijian Wu; Junjiang Sun; Taiping Zhang; Chaoying Yin; Fang Yin; Terry Van Dyke; R Jude Samulski; Paul E Monahan
Optimization of self-complementary AAV vectors for liver-directed expression results in sustained correction of hemophilia B at low vector dose.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(2):280-9.
2008: Paul E Monahan
Experimental animal use in the study of haemophilic bleeding.
Haemophilia : the official journal of the World Federation of Hemophilia 2008;14(1):112-6.
2007: Feng Liu; Demet Sag; Jue Wang; Lisa M Shollenberger; Feilong Niu; Xing Yuan; Shyh-Dar Li; Mike Thompson; Paul E Monahan
Sine-wave current for efficient and safe in vivo gene transfer.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(10):1842-7.
2007: Paul E Monahan
Neonatal immune tolerance for hemophilia: can we "tolerate" new paradigms for gene therapy trials?
Journal of thrombosis and haemostasis : JTH 2007;5(9):1801-4.
2007: J Teitel; Erik Berntorp; P Collins; Roseline d'Oiron; Bruce M Ewenstein; E Gomperts; Jenny Goudemand; Alessandro Gringeri; Nigel S Key; Cindy A Leissinger; Paul E Monahan; G Young
A systematic approach to controlling problem bleeds in patients with severe congenital haemophilia A and high-titre inhibitors.
Haemophilia : the official journal of the World Federation of Hemophilia 2007;13(3):256-63.
2007: T-P Zhang; Da-Yun Jin; R M Wardrop; Tong Gui; Robert Maile; Jeffrey Frelinger; Darrel W Stafford; Paul E Monahan
Transgene expression levels and kinetics determine risk of humoral immune response modeled in factor IX knockout and missense mutant mice.
Gene therapy 2007;14(5):429-40.
2007: Tong Gui; Adili Reheman; William K Funkhouser; Dwight A Bellinger; John R Hagaman; Darrel W Stafford; Paul E Monahan; Heyu Ni
In vivo response to vascular injury in the absence of factor IX: examination in factor IX knockout mice.
Thrombosis research 2007;121(2):225-34.
2006: Karyn B Stitzenberg; Mark D Piehl; Paul E Monahan; J Duncan Phillips
Interval laparoscopic appendectomy for appendicitis complicated by pylephlebitis.
JSLS : Journal of the Society of Laparoendoscopic Surgeons / Society of Laparoendoscopic Surgeons 2006;10(1):108-13.
2005: Dmitri V Kravtsov; Paul E Monahan; David Gailani
A classification system for cross-reactive material-negative factor XI deficiency.
Blood 2005;105(12):4671-3.
2005: Iris Schrijver; Debbie W Hong; Lisa Mandle; Carol D Jones; Donna DiMichele; Paul E Monahan; James L Zehnder
High frequency of premature termination mutations in the factor V gene: three factor V deficiency case reports and a mutation review.
Thrombosis and haemostasis 2005;93(3):610-1.
2004: Paul E Monahan; Louis M Aledort
Factors affecting choice of hemostatic agent for the hemophilia patient with an inhibitor antibody.
American journal of hematology 2004;77(4):346-50.
2004: Kevin E Van Cott; Paul E Monahan; Timothy C Nichols; William H Velander
Haemophilic factors produced by transgenic livestock: abundance that can enable alternative therapies worldwide.
Haemophilia : the official journal of the World Federation of Hemophilia 2004;10 Suppl 4():70-6.
2004: Da-Yun Jin; Tai-Ping Zhang; Tong Gui; Darrel W Stafford; Paul E Monahan
Creation of a mouse expressing defective human factor IX.
Blood 2004;104(6):1733-9.
2004: Mike Douvas; Paul E Monahan
Life-threatening thrombosis complicating the management of hepatic hemorrhage: anticoagulant treatment in a newborn with hemophilia B.
Journal of pediatric hematology/oncology 2004;26(4):258-63.
2003: Douglass Mccarty; Haiyan Fu; Paul E Monahan; C E Toulson; P Naik; R Jude Samulski
Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo.
Gene therapy 2003;10(26):2112-8.
2002: Matthew W Richardson; Geoffrey A Allen; Paul E Monahan
Thrombosis in children: current perspective and distinct challenges.
Thrombosis and haemostasis 2002;88(6):900-11.
2002: Paul E Monahan; Gilbert C White
Hemophilia gene therapy: update.
Current opinion in hematology 2002;9(5):430-6.
2002: Paul E Monahan; Karin Jooss; Mark S Sands
Safety of adeno-associated virus gene therapy vectors: a current evaluation.
Expert opinion on drug safety 2002;1(1):79-91.
2001: Hengjun Chao; Paul E Monahan; Y Liu; R Jude Samulski; Christopher E Walsh
Sustained and complete phenotype correction of hemophilia B mice following intramuscular injection of AAV1 serotype vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;4(3):217-22.
2001: Julie Blatt; Stuart Gold; Joseph M Wiley; Paul E Monahan; H C Cooper; D Harvey
Off-label use of recombinant factor VIIa in patients following bone marrow transplantation.
Bone marrow transplantation 2001;28(4):405-7.
2001: Douglass Mccarty; Paul E Monahan; R Jude Samulski
Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis.
Gene therapy 2001;8(16):1248-54.
2000: Paul E Monahan; R Jude Samulski
Adeno-associated virus vectors for gene therapy: more pros than cons?
Molecular medicine today 2000;6(11):433-40.
2000: Ajay K Malik; Paul E Monahan; David L Allen; B G Chen; R Jude Samulski; Kotoku Kurachi
Kinetics of recombinant adeno-associated virus-mediated gene transfer.
Journal of virology 2000;74(8):3555-65.
2000: Paul E Monahan; R Jude Samulski
AAV vectors: is clinical success on the horizon?
Gene therapy 2000;7(1):24-30.
1999: Hengjun Chao; R Jude Samulski; Dwight A Bellinger; Paul E Monahan; Timothy C Nichols; Christopher E Walsh
Persistent expression of canine factor IX in hemophilia B canines.
Gene therapy 1999;6(10):1695-704.
1998: Paul E Monahan; R Jude Samulski; J Tazelaar; Xiao Xiao; Timothy C Nichols; Dwight A Bellinger; Marjorie S Read; Christopher E Walsh
Direct intramuscular injection with recombinant AAV vectors results in sustained expression in a dog model of hemophilia.
Gene therapy 1998;5(1):40-9.
1991: J R Kerrigan; PM Martha; Richard J Krieg; T A Queen; Paul E Monahan; Alan D Rogol
Augmented hypothalamic proopiomelanocortin gene expression with pubertal development in the male rat: evidence for an androgen receptor-independent action.
Endocrinology 1991;128(2):1029-35.