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Robert Mooney

Research Profile

Chemicals & Drugs

Phenomena

Phosphorylation

Physiology

Anatomy

Living Beings

Mouse
Rats

Disorders

Insulin Resistance

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Publications

TOP 3
Alicia H Clementi; Allison M Gaudy; Leonidas G Koniaris; Teresa Zimmers; Robert A Mooney
Deletion of interleukin-6 improves pyruvate tolerance without altering hepatic insulin signaling in the leptin receptor-deficient mouse.
Erik R Sampson; Edward M Schwarz; Ye Tian; Hani Awad; Susan V Bukata; Di Chen; Matthew J Hilton; Robert A Mooney; Regis J O'Keefe; J Edward Puzas; Randy N Rosier; Michael J Zuscik
Teriparatide as a chondroregenerative therapy for injury-induced osteoarthritis.
Robert A Mooney; Randy N Rosier; Erik R Sampson; Jaclyn Lerea; Michael J Zuscik
High-fat diet accelerates progression of osteoarthritis after meniscal/ligamentous injury.

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All Publications

2011: Alicia H Clementi; Allison M Gaudy; Leonidas G Koniaris; Teresa Zimmers; Robert A Mooney
Deletion of interleukin-6 improves pyruvate tolerance without altering hepatic insulin signaling in the leptin receptor-deficient mouse.
Metabolism: clinical and experimental 2011;60(11):1610-9.
2011: Erik R Sampson; Edward M Schwarz; Ye Tian; Hani Awad; Susan V Bukata; Di Chen; Matthew J Hilton; Robert A Mooney; Regis J O'Keefe; J Edward Puzas; Randy N Rosier; Michael J Zuscik
Teriparatide as a chondroregenerative therapy for injury-induced osteoarthritis.
Science translational medicine 2011;3(101):101ra93.
2011: Robert A Mooney; Randy N Rosier; Erik R Sampson; Jaclyn Lerea; Michael J Zuscik
High-fat diet accelerates progression of osteoarthritis after meniscal/ligamentous injury.
Arthritis research & therapy 2011;13(6):R198.
2010: Chad A Galloway; John Ashton; Janet D Sparks; Robert A Mooney; Harold C Smith
Metabolic regulation of APOBEC-1 complementation factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytes.
Biochimica et biophysica acta 2010;1802(11):976-85.
2009: Alicia H Clementi; Allison M Gaudy; Nico van Rooijen; Robert H Pierce; Robert A Mooney
Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling.
Biochimica et biophysica acta 2009;1792(11):1062-72.
2008: Loralei L Thornburg; Kristin M Knight; C Jeanne Peterson; Karin B McCall; Robert A Mooney; Eva K Pressman
Maternal serum alpha-fetoprotein values in type 1 and type 2 diabetic patients.
American journal of obstetrics and gynecology 2008;199(2):135.e1-5.
2007: Robert A Mooney
Counterpoint: Interleukin-6 does not have a beneficial role in insulin sensitivity and glucose homeostasis.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;102(2):816-8; discussion 818-9.
2005: Peter J Klover; Alicia H Clementi; Robert A Mooney
Interleukin-6 depletion selectively improves hepatic insulin action in obesity.
Endocrinology 2005;146(8):3417-27.
2004: Charles LeVea; Jay E Reeder; Robert A Mooney
EGF-dependent cell cycle progression is controlled by density-dependent regulation of Akt activation.
Experimental cell research 2004;297(1):272-84.
2004: Peter J Klover; Robert A Mooney
Hepatocytes: critical for glucose homeostasis.
The international journal of biochemistry & cell biology 2004;36(5):753-8.
2003: Jeffrey P Baliff; Robert A Mooney
New developments in prenatal screening for Down syndrome.
American journal of clinical pathology 2003;120 Suppl():S14-24.
2003: Peter J Klover; Teresa Zimmers; Leonidas G Koniaris; Robert A Mooney
Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice.
Diabetes 2003;52(11):2784-9.
2003: Bruno M Polliotti; A Gordon Fry; Devereux N Saller; Robert A Mooney; Christopher Cox; Rita K Miller
Second-trimester maternal serum placental growth factor and vascular endothelial growth factor for predicting severe, early-onset preeclampsia.
Obstetrics and gynecology 2003;101(6):1266-74.
2003: Joseph J Senn; Peter J Klover; Irena A Nowak; Teresa Zimmers; Leonidas G Koniaris; Richard W Furlanetto; Robert A Mooney
Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes.
The Journal of biological chemistry 2003;278(16):13740-6.
2003: Robert A Mooney; Charles LeVea
The leukocyte common antigen-related protein LAR: candidate PTP for inhibitory targeting.
Current topics in medicinal chemistry 2003;3(7):809-19.
2002: Joseph J Senn; Peter J Klover; Irena A Nowak; Robert A Mooney
Interleukin-6 induces cellular insulin resistance in hepatocytes.
Diabetes 2002;51(12):3391-9.
2002: Javelle R Symons; Charles LeVea; Robert A Mooney
Expression of the leucocyte common antigen-related (LAR) tyrosine phosphatase is regulated by cell density through functional E-cadherin complexes.
The Biochemical journal 2002;365(Pt 2):513-9.
2001: Robert A Mooney; Joseph J Senn; S Cameron; N Inamdar; L M Boivin; Y Shang; R W Furlanetto
Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance.
The Journal of biological chemistry 2001;276(28):25889-93.
2000: Charles LeVea; Carl T McGary; J R Symons; Robert A Mooney
PTP LAR expression compared to prognostic indices in metastatic and non-metastatic breast cancer.
Breast cancer research and treatment 2000;64(2):221-8.
1999: L A Bleyle; Y Peng; C Ellis; Robert A Mooney
Dissociation of PTPase levels from their modulation of insulin receptor signal transduction.
Cellular signalling 1999;11(10):719-25.
1997: Devereux N Saller; Jacob A Canick; Leonard H Kellner; N C Rose; J Garza; CA French; Robert A Mooney
Maternal serum analyte levels in pregnancies with fetal Down syndrome resulting from translocations.
American journal of obstetrics and gynecology 1997;177(4):879-81.
1997: Thuy L Phung; Robert A Mooney; D T Kulas; Charles E Sparks; Janet D Sparks
Suppression of the protein tyrosine phosphatase LAR reduces apolipoprotein B secretion by McA-RH7777 rat hepatoma cells.
Biochemical and biophysical research communications 1997;237(2):367-71.
1997: Robert A Mooney; D T Kulas; L A Bleyle; J S Novak
The protein tyrosine phosphatase LAR has a major impact on insulin receptor dephosphorylation.
Biochemical and biophysical research communications 1997;235(3):709-12.
1996: D T Kulas; Gregory G Freund; Robert A Mooney
The transmembrane protein-tyrosine phosphatase CD45 is associated with decreased insulin receptor signaling.
The Journal of biological chemistry 1996;271(2):755-60.
1996: D T Kulas; B J Goldstein; Robert A Mooney
The transmembrane protein-tyrosine phosphatase LAR modulates signaling by multiple receptor tyrosine kinases.
The Journal of biological chemistry 1996;271(2):748-54.
1995: Robert A Mooney; D A Arvan; Devereux N Saller; C A French; C J Peterson
Decreased maternal serum hCG levels with increasing gravidity and parity.
Obstetrics and gynecology 1995;86(6):900-5.
1995: D T Kulas; W R Zhang; B J Goldstein; R W Furlanetto; Robert A Mooney
Insulin receptor signaling is augmented by antisense inhibition of the protein tyrosine phosphatase LAR.
The Journal of biological chemistry 1995;270(6):2435-8.
1995: Gregory G Freund; J G Wittig; Robert A Mooney
The PI3-kinase serine kinase phosphorylates its p85 subunit and IRS-1 in PI3-kinase/IRS-1 complexes.
Biochemical and biophysical research communications 1995;206(1):272-8.
1994: B A Way; Robert A Mooney
Differential effects of phosphotyrosine phosphatase expression on hormone-dependent and independent pp60c-src activity.
Molecular and cellular biochemistry 1994;139(2):167-75.
1994: Robert A Mooney; C J Peterson; C A French; Devereux N Saller; D A Arvan
Effectiveness of combining maternal serum alpha-fetoprotein and hCG in a second-trimester screening program for Down syndrome.
Obstetrics and gynecology 1994;84(2):298-303.
1994: Gregory G Freund; D T Kulas; B A Way; Robert A Mooney
Functional insulin and insulin-like growth factor-1 receptors are preferentially expressed in multiple myeloma cell lines as compared to B-lymphoblastoid cell lines.
Cancer research 1994;54(12):3179-85.
1993: B A Way; Robert A Mooney
Activation of phosphatidylinositol-3-kinase by platelet-derived growth factor and insulin-like growth factor-1 is inhibited by a transmembrane phosphotyrosine phosphatase.
The Journal of biological chemistry 1993;268(35):26409-15.
1993: Gregory G Freund; D T Kulas; Robert A Mooney
Insulin and IGF-1 increase mitogenesis and glucose metabolism in the multiple myeloma cell line, RPMI 8226.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(4):1811-20.
1992: Robert A Mooney; Gregory G Freund; B A Way; K L Bordwell
Expression of a transmembrane phosphotyrosine phosphatase inhibits cellular response to platelet-derived growth factor and insulin-like growth factor-1.
The Journal of biological chemistry 1992;267(33):23443-6.
1992: Robert A Mooney; K L Bordwell
Differential dephosphorylation of the insulin receptor and its 160-kDa substrate (pp160) in rat adipocytes.
The Journal of biological chemistry 1992;267(20):14054-60.
1992: Robert A Mooney; K L Bordwell
Insulin stimulates the tyrosine phosphorylation of a 61-kilodalton protein in rat adipocytes.
Endocrinology 1992;130(3):1533-8.
1991: Robert A Mooney; K L Bordwell
Counter-regulation by insulin and isoprenaline of a prominent fat-associated phosphoprotein doublet in rat adipocytes.
The Biochemical journal 1991;274 ( Pt 2)():433-8.
1989: Robert A Mooney; D A Green
Insulin receptor dephosphorylation in permeabilized adipocytes is inhibitable by manganese and independent of receptor kinase activity.
Biochemical and biophysical research communications 1989;162(3):1200-6.
1989: Robert A Mooney; D L Anderson
Phosphorylation of the insulin receptor in permeabilized adipocytes is coupled to a rapid dephosphorylation reaction.
The Journal of biological chemistry 1989;264(12):6850-7.
1989: Robert A Mooney; K L Bordwell; S Luhowskyj; J E Casnellie
The insulin-like effect of vanadate on lipolysis in rat adipocytes is not accompanied by an insulin-like effect on tyrosine phosphorylation.
Endocrinology 1989;124(1):422-9.
1988: T K Mayer; Robert A Mooney
Laboratory analyses for steroid hormone receptors, and their applications to clinical medicine.
Clinica chimica acta; international journal of clinical chemistry 1988;172(1):1-33.
1988: Robert A Mooney; B L McGorty; C A French; D A Arvan
An alpha-fetoprotein radioimmunoassay for use in maternal serum screening for Down's syndrome: limitations and improvements.
Clinica chimica acta; international journal of clinical chemistry 1988;171(2-3):325-31.