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Peter Moore

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Ribosomes

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All Publications

2012: Peter B Moore
A short, informal history of the biological sciences at Yale University.
The Yale journal of biology and medicine 2012;85(4):551-8.
2012: Peter B Moore
How should we think about the ribosome?
Annual review of biophysics 2012;41():1-19.
2011: Peter B Moore; Thomas A Steitz
The roles of RNA in the synthesis of protein.
Cold Spring Harbor perspectives in biology 2011;3(11):a003780.
2009: Güliz Gürel; Gregor Blaha; Thomas A Steitz; Peter B Moore
Structures of triacetyloleandomycin and mycalamide A bind to the large ribosomal subunit of Haloarcula marismortui.
Antimicrobial agents and chemotherapy 2009;53(12):5010-4.
2009: Peter B Moore
On the relationship between diffraction patterns and motions in macromolecular crystals.
Structure (London, England : 1993) 2009;17(10):1307-15.
2009: Güliz Gürel; Gregor Blaha; Peter B Moore; Thomas A Steitz
U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
Journal of molecular biology 2009;389(1):146-56.
2009: Peter B Moore
The ribosome returned.
Journal of biology 2009;8(1):8.
2008: Gregor Blaha; Güliz Gürel; Susan J Schroeder; Peter B Moore; Thomas A Steitz
Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
Journal of molecular biology 2008;379(3):505-19.
2007: Susan J Schroeder; Gregor Blaha; Peter B Moore
Negamycin binds to the wall of the nascent chain exit tunnel of the 50S ribosomal subunit.
Antimicrobial agents and chemotherapy 2007;51(12):4462-5.
2007: Peter B Moore
Let's call the whole thing off: some thoughts on the protein structure initiative.
Structure (London, England : 1993) 2007;15(11):1350-2.
2007: Hong Jin; J Patrick Loria; Peter B Moore
Solution structure of an rRNA substrate bound to the pseudouridylation pocket of a box H/ACA snoRNA.
Molecular cell 2007;26(2):205-15.
2007: Susan J Schroeder; Gregor Blaha; Julian Tirado-Rives; Thomas A Steitz; Peter B Moore
The structures of antibiotics bound to the E site region of the 50 S ribosomal subunit of Haloarcula marismortui: 13-deoxytedanolide and girodazole.
Journal of molecular biology 2007;367(5):1471-9.
2006: N R Voss; Mark Gerstein; Thomas A Steitz; Peter B Moore
The geometry of the ribosomal polypeptide exit tunnel.
Journal of molecular biology 2006;360(4):893-906.
2005: Daqi Tu; Gregor Blaha; Peter B Moore; Thomas A Steitz
Gene replacement in Haloarcula marismortui: construction of a strain with two of its three chromosomal rRNA operons deleted.
Extremophiles : life under extreme conditions 2005;9(6):427-35.
2005: Peter B Moore
Structural biology. A ribosomal coup: E. coli at last!
Science (New York, N.Y.) 2005;310(5749):793-5.
2005: Daqi Tu; Gregor Blaha; Peter B Moore; Thomas A Steitz
Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Cell 2005;121(2):257-70.
2004: Daniel J Klein; Peter B Moore; Thomas A Steitz
The contribution of metal ions to the structural stability of the large ribosomal subunit.
RNA (New York, N.Y.) 2004;10(9):1366-79.
2004: Daniel J Klein; Peter B Moore; Thomas A Steitz
The roles of ribosomal proteins in the structure assembly, and evolution of the large ribosomal subunit.
Journal of molecular biology 2004;340(1):141-77.
2004: Helen J Merianos; Jimin Wang; Peter B Moore
The structure of a ribosomal protein S8/spc operon mRNA complex.
RNA (New York, N.Y.) 2004;10(6):954-64.
2004: Catherine F Turner; Peter B Moore
The solution structure of ribosomal protein L18 from Bacillus stearothermophilus.
Journal of molecular biology 2004;335(3):679-84.
2003: T Martin Schmeing; Peter B Moore; Thomas A Steitz
Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit.
RNA (New York, N.Y.) 2003;9(11):1345-52.
2003: Thomas A Steitz; Peter B Moore
RNA, the first macromolecular catalyst: the ribosome is a ribozyme.
Trends in biochemical sciences 2003;28(8):411-8.
2003: Jeffrey L. Hansen; Peter B Moore; Thomas A Steitz
Structures of five antibiotics bound at the peptidyl transferase center of the large ribosomal subunit.
Journal of molecular biology 2003;330(5):1061-75.
2003: Peter B Moore; Thomas A Steitz
After the ribosome structures: how does peptidyl transferase work?
RNA (New York, N.Y.) 2003;9(2):155-9.
2003: Pramodh Vallurupalli; Peter B Moore
The solution structure of the loop E region of the 5S rRNA from spinach chloroplasts.
Journal of molecular biology 2003;325(5):843-56.
2003: Peter B Moore; Thomas A Steitz
The structural basis of large ribosomal subunit function.
Annual review of biochemistry 2003;72():813-50.
2003: Szilvia Szép; Jimin Wang; Peter B Moore
The crystal structure of a 26-nucleotide RNA containing a hook-turn.
RNA (New York, N.Y.) 2003;9(1):44-51.
2002: Jeffrey L. Hansen; T Martin Schmeing; Peter B Moore; Thomas A Steitz
Structural insights into peptide bond formation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(18):11670-5.
2002: Peter B Moore; Thomas A Steitz
The involvement of RNA in ribosome function.
Nature 2002;418(6894):229-35.
2002: Jeffrey L. Hansen; Joseph A Ippolito; Nenad Ban; Poul Nissen; Peter B Moore; Thomas A Steitz
The structures of four macrolide antibiotics bound to the large ribosomal subunit.
Molecular cell 2002;10(1):117-28.
2002: T Martin Schmeing; Amy C Seila; Jeffrey L. Hansen; Betty Freeborn; Juliane K Soukup; Stephen A Scaringe; Scott A Strobel; Peter B Moore; Thomas A Steitz
A pre-translocational intermediate in protein synthesis observed in crystals of enzymatically active 50S subunits.
Nature structural biology 2002;9(3):225-30.
2001: Jonathan DiNitto; JP Rife; Peter B Moore
The structure of helix III in Xenopus oocyte 5 S rRNA: an RNA stem containing a two-nucleotide bulge.
Journal of molecular biology 2001;312(4):823-32.
2001: J J Warren; Peter B Moore
Application of dipolar coupling data to the refinement of the solution structure of the sarcin-ricin loop RNA.
Journal of biomolecular NMR 2001;20(4):311-23.
2001: Daniel J Klein; T Martin Schmeing; Peter B Moore; Thomas A Steitz
The kink-turn: a new RNA secondary structure motif.
The EMBO journal 2001;20(15):4214-21.
2001: Poul Nissen; Joseph A Ippolito; Nenad Ban; Peter B Moore; Thomas A Steitz
RNA tertiary interactions in the large ribosomal subunit: the A-minor motif.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(9):4899-903.
2001: Peter B Moore
The ribosome at atomic resolution.
Biochemistry 2001;40(11):3243-50.
2001: Peter B Moore
The ribosome in the 21st century: the post-structural era.
Cold Spring Harbor symposia on quantitative biology 2001;66():607-14.
2001: Jeffrey L. Hansen; T Martin Schmeing; Daniel J Klein; Joseph A Ippolito; Nenad Ban; Poul Nissen; Betty Freeborn; Peter B Moore; Thomas A Steitz
Progress toward an understanding of the structure and enzymatic mechanism of the large ribosomal subunit.
Cold Spring Harbor symposia on quantitative biology 2001;66():33-42.
2000: Poul Nissen; Jeffrey L. Hansen; Nenad Ban; Peter B Moore; Thomas A Steitz
The structural basis of ribosome activity in peptide bond synthesis.
Science (New York, N.Y.) 2000;289(5481):920-30.
2000: Nenad Ban; Poul Nissen; Jeffrey L. Hansen; Peter B Moore; Thomas A Steitz
The complete atomic structure of the large ribosomal subunit at 2.4 A resolution.
Science (New York, N.Y.) 2000;289(5481):905-20.
2000: Huafang Shi; Peter B Moore
The crystal structure of yeast phenylalanine tRNA at 1.93 A resolution: a classic structure revisited.
RNA (New York, N.Y.) 2000;6(8):1091-105.
1999: M J Bloemink; Peter B Moore
Phosphorylation of ribosomal protein L18 is required for its folding and binding to 5S rRNA.
Biochemistry 1999;38(40):13385-90.
1999: Nenad Ban; Poul Nissen; Jeffrey L. Hansen; M Capel; Peter B Moore; Thomas A Steitz
Placement of protein and RNA structures into a 5 A-resolution map of the 50S ribosomal subunit.
Nature 1999;400(6747):841-7.
1999: Peter B Moore
Structural motifs in RNA.
Annual review of biochemistry 1999;68():287-300.
1999: JP Rife; S C Stallings; C C Correll; A Dallas; Thomas A Steitz; Peter B Moore
Comparison of the crystal and solution structures of two RNA oligonucleotides.
Biophysical journal 1999;76(1 Pt 1):65-75.
1998: K Seggerson; Peter B Moore
Structure and stability of variants of the sarcin-ricin loop of 28S rRNA: NMR studies of the prokaryotic SRL and a functional mutant.
RNA (New York, N.Y.) 1998;4(10):1203-15.
1998: JP Rife; C S Cheng; Peter B Moore; Scott A Strobel
N 2-methylguanosine is iso-energetic with guanosine in RNA duplexes and GNRA tetraloops.
Nucleic acids research 1998;26(16):3640-4.
1998: Nenad Ban; Betty Freeborn; Poul Nissen; Pawel A Penczek; Robert A Grassucci; R Sweet; J Frank; Peter B Moore; Thomas A Steitz
A 9 A resolution X-ray crystallographic map of the large ribosomal subunit.
Cell 1998;93(7):1105-15.
1998: JP Rife; Peter B Moore
The structure of a methylated tetraloop in 16S ribosomal RNA.
Structure (London, England : 1993) 1998;6(6):747-56.
1998: J L Diener; Peter B Moore
Solution structure of a substrate for the archaeal pre-tRNA splicing endonucleases: the bulge-helix-bulge motif.
Molecular cell 1998;1(6):883-94.
1998: Peter B Moore
The three-dimensional structure of the ribosome and its components.
Annual review of biophysics and biomolecular structure 1998;27():35-58.
1997: A Dallas; Peter B Moore
The loop E-loop D region of Escherichia coli 5S rRNA: the solution structure reveals an unusual loop that may be important for binding ribosomal proteins.
Structure (London, England : 1993) 1997;5(12):1639-53.
1997: C C Correll; Betty Freeborn; Peter B Moore; Thomas A Steitz
Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain.
Cell 1997;91(5):705-12.
1997: C C Correll; Betty Freeborn; Peter B Moore; Thomas A Steitz
Use of chemically modified nucleotides to determine a 62-nucleotide RNA crystal structure: a survey of phosphorothioates, Br, Pt and Hg.
Journal of biomolecular structure & dynamics 1997;15(2):165-72.
1997: J Lapham; JP Rife; Peter B Moore; Donald M Crothers
Measurement of diffusion constants for nucleic acids by NMR.
Journal of biomolecular NMR 1997;10(3):255-62.
1997: S C Stallings; Peter B Moore
The structure of an essential splicing element: stem loop IIa from yeast U2 snRNA.
Structure (London, England : 1993) 1997;5(9):1173-85.
1997: J Czworkowski; Peter B Moore
The conformational properties of elongation factor G and the mechanism of translocation.
Biochemistry 1997;36(33):10327-34.
1997: D C Schweisguth; Peter B Moore
On the conformation of the anticodon loops of initiator and elongator methionine tRNAs.
Journal of molecular biology 1997;267(3):505-19.
1997: Peter B Moore
Ribosomes: protein synthesis in slow motion.
Current biology : CB 1997;7(3):R179-81.
1996: J Czworkowski; Peter B Moore
The elongation phase of protein synthesis.
Progress in nucleic acid research and molecular biology 1996;54():293-332.
1995: Peter B Moore
Molecular mimicry in protein synthesis?
Science (New York, N.Y.) 1995;270(5241):1453-4.
1995: Peter B Moore
Ribosomes seen through a glass less darkly.
Structure (London, England : 1993) 1995;3(9):851-2.
1995: Alexander A Szewczak; Peter B Moore
The sarcin/ricin loop, a modular RNA.
Journal of molecular biology 1995;247(1):81-98.
1994: J Czworkowski; J Wang; Thomas A Steitz; Peter B Moore
The crystal structure of elongation factor G complexed with GDP, at 2.7 A resolution.
The EMBO journal 1994;13(16):3661-8.
1994: D C Schweisguth; B S Chelladurai; Allen W Nicholson; Peter B Moore
Structural characterization of a ribonuclease III processing signal.
Nucleic acids research 1994;22(4):604-12.
1993: Alexander A Szewczak; Peter B Moore; Y L Chang; Ira G Wool
The conformation of the sarcin/ricin loop from 28S ribosomal RNA.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(20):9581-5.
1993: Alexander A Szewczak; Greg Tucker-Kellogg; Peter B Moore
Assignment of NH resonances in nucleic acids using natural abundance 15N-1H correlation spectroscopy with spin-echo and gradient pulses.
FEBS letters 1993;327(3):261-4.
1992: C Cheong; Peter B Moore
Solution structure of an unusually stable RNA tetraplex containing G- and U-quartet structures.
Biochemistry 1992;31(36):8406-14.
1992: S A White; Michael Nilges; A Huang; Axel T Brünger; Peter B Moore
NMR analysis of helix I from the 5S RNA of Escherichia coli.
Biochemistry 1992;31(6):1610-21.
1991: Alexander A Szewczak; K R Webster; Eleanor K Spicer; Peter B Moore
An NMR characterization of the regA protein-binding site of bacteriophage T4 gene 44 mRNA.
The Journal of biological chemistry 1991;266(27):17832-7.
1991: Alexander A Szewczak; Y L Chan; Peter B Moore; Ira G Wool
On the conformation of the alpha sarcin stem-loop of 28S rRNA.
Biochimie 1991;73(7-8):871-7.
1991: J Kim; C Cheong; Peter B Moore
Tetramerization of an RNA oligonucleotide containing a GGGG sequence.
Nature 1991;351(6324):331-2.
1990: Alexander A Szewczak; S A White; D T Gewirth; Peter B Moore
On the use of T7 RNA polymerase transcripts for physical investigation.
Nucleic acids research 1990;18(14):4139-42.
1989: P Zhang; P Popieniek; Peter B Moore
Physical studies of 5S RNA variants at position 66.
Nucleic acids research 1989;17(21):8645-56.
1989: P Zhang; R Rycyna; Peter B Moore
A study of the conformation of 5S RNA by 31P NMR.
Nucleic acids research 1989;17(18):7295-302.
1989: P Zhang; Peter B Moore
An NMR study of the helix V-loop E region of the 5S RNA from Escherichia coli.
Biochemistry 1989;28(11):4607-15.
1988: D T Gewirth; Peter B Moore
Exploration of the L18 binding site on 5S RNA by deletion mutagenesis.
Nucleic acids research 1988;16(22):10717-32.
1988: M S Capel; M Kjeldgaard; Donald M Engelman; Peter B Moore
Positions of S2, S13, S16, S17, S19 and S21 in the 30 S ribosomal subunit of Escherichia coli.
Journal of molecular biology 1988;200(1):65-87.
1988: Peter B Moore
The ribosome returns.
Nature 1988;331(6153):223-7.
1988: Peter B Moore
Structure-function correlations in the small ribosomal subunit from Escherichia coli.
Annual review of biophysics and biophysical chemistry 1988;17():349-67.
1988: Peter B Moore; S Abo; Betty Freeborn; D T Gewirth; Neocles Leontis; G Sun
Preparation of 5S RNA-related materials for nuclear magnetic resonance and crystallography studies.
Methods in enzymology 1988;164():158-74.
1987: D T Gewirth; Peter B Moore
Effects of mutation on the downfield proton nuclear magnetic resonance spectrum of the 5S RNA of Escherichia coli.
Biochemistry 1987;26(18):5657-65.
1987: D T Gewirth; S R Abo; Neocles Leontis; Peter B Moore
Secondary structure of 5S RNA: NMR experiments on RNA molecules partially labeled with nitrogen-15.
Biochemistry 1987;26(16):5213-20.
1987: Peter B Moore
On the modus operandi of the ribosome.
Cold Spring Harbor symposia on quantitative biology 1987;52():721-8.
1984: M J Kime; D T Gewirth; Peter B Moore
Assignment of resonances in the downfield proton spectrum of Escherichia coli 5S RNA and its nucleoprotein complexes using components of a ribonuclease-resistant fragment.
Biochemistry 1984;23(15):3559-68.
1984: V Ramakrishnan; M Capel; M Kjeldgaard; Donald M Engelman; Peter B Moore
Positions of proteins S14, S18 and S20 in the 30 S ribosomal subunit of Escherichia coli.
Journal of molecular biology 1984;174(2):265-84.
1983: Peter B Moore; M J Kime; Neocles Leontis; S S Abdel-Meguid
Physical studies on a nucleoprotein from the ribosome of E. coli.
Journal of biomolecular structure & dynamics 1983;1(2):383-94.