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Dino Moras

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

TOP 3
Shimizu Satoru; Juan Ella Czarina Magat; Sato Yoshiteru; Miyashita Yu-Ichiro; Hoque Md Mominul; Suzuki Kaoru; Sagara Tsubasa; Tsunoda Masaru; Sekiguchi Takeshi; Dock-Bregeon Anne-Catherine; Moras Dino; Takénaka Akio
Two complementary enzymes for threonylation of tRNA in crenarchaeota: crystal structure of Aeropyrum pernix threonyl-tRNA synthetase lacking a cis-editing domain.
Lippert W Peter; Burschka Christian; Götz Kathrin; Kaupp Martin; Ivanova Diana; Gaudon Claudine; Sato Yoshiteru; Antony Pierre; Rochel Natacha; Moras Dino; Gronemeyer Hinrich; Tacke Reinhold
Silicon analogues of the RXR-selective retinoid agonist SR11237 (BMS649): chemistry and biology.
Albou Laurent-Philippe; Schwarz Benjamin; Poch Olivier; Wurtz Jean Marie; Moras Dino
Defining and characterizing protein surface using alpha shapes.

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All Publications

2009: Shimizu Satoru; Juan Ella Czarina Magat; Sato Yoshiteru; Miyashita Yu-Ichiro; Hoque Md Mominul; Suzuki Kaoru; Sagara Tsubasa; Tsunoda Masaru; Sekiguchi Takeshi; Dock-Bregeon Anne-Catherine; Moras Dino; Takénaka Akio
Two complementary enzymes for threonylation of tRNA in crenarchaeota: crystal structure of Aeropyrum pernix threonyl-tRNA synthetase lacking a cis-editing domain.
Journal of molecular biology 2009;394(2):286-96.
2009: Lippert W Peter; Burschka Christian; Götz Kathrin; Kaupp Martin; Ivanova Diana; Gaudon Claudine; Sato Yoshiteru; Antony Pierre; Rochel Natacha; Moras Dino; Gronemeyer Hinrich; Tacke Reinhold
Silicon analogues of the RXR-selective retinoid agonist SR11237 (BMS649): chemistry and biology.
ChemMedChem 2009;4(7):1143-52.
2009: Albou Laurent-Philippe; Schwarz Benjamin; Poch Olivier; Wurtz Jean Marie; Moras Dino
Defining and characterizing protein surface using alpha shapes.
Proteins 2009;76(1):1-12.
2009: Beck Yannick; Delaporte Claude; Moras Dino; Richards Geoff; Billas Isabelle M L
The ligand-binding domains of the three RXR-USP nuclear receptor types support distinct tissue and ligand specific hormonal responses in transgenic Drosophila.
Developmental biology 2009;330(1):1-11.
2009: Bovet Cédric; Plet Benoit; Ruff Marc; Eiler Sylvia; Granger Florence; Panagiotidis Andreas; Wenzel Ryan; Nazabal Alexis; Moras Dino; Zenobi Renato
Towards high-throughput identification of endocrine disrupting compounds with mass spectrometry.
Toxicology in vitro : an international journal published in association with BIBRA 2009;23(4):704-9.
2009: Michel Fabrice; Crucifix Corinne; Granger Florence; Eiler Sylvia; Mouscadet Jean-François; Korolev Sergei; Agapkina Julia; Ziganshin Rustam; Gottikh Marina; Nazabal Alexis; Emiliani Stéphane; Benarous Richard; Moras Dino; Schultz Patrick; Ruff Marc
Structural basis for HIV-1 DNA integration in the human genome, role of the LEDGF/P75 cofactor.
The EMBO journal 2009;28(7):980-91.
2009: Iwema Thomas; Chaumot Arnaud; Studer Romain A; Robinson-Rechavi Marc; Billas Isabelle M L; Moras Dino; Laudet Vincent; Bonneton François
Structural and evolutionary innovation of the heterodimerization interface between USP and the ecdysone receptor ECR in insects.
Molecular biology and evolution 2009;26(4):753-68.
2009: Abdulrahman Wassim; Uhring Muriel; Kolb-Cheynel Isabelle; Garnier Jean-Marie; Moras Dino; Rochel Natacha; Busso Didier; Poterszman Arnaud
A set of baculovirus transfer vectors for screening of affinity tags and parallel expression strategies.
Analytical biochemistry 2009;385(2):383-5.
2009: Moras Dino
Structure of full-length PPARgamma-RXRalpha: a snapshot of a functional complex?
Cell metabolism 2009;9(1):8-10.
2009: Tocchini-Valentini Giuseppe D; Rochel Natacha; Escriva Hector; Germain Pierre; Peluso-Iltis Carole; Paris Mathilde; Sanglier-Cianferani Sarah; Van Dorsselaer Alain; Moras Dino; Laudet Vincent
Structural and functional insights into the ligand-binding domain of a nonduplicated retinoid X nuclear receptor from the invertebrate chordate amphioxus.
The Journal of biological chemistry 2009;284(3):1938-48.
2008: Eelen Guy; Valle Noelia; Sato Yoshiteru; Rochel Natacha; Verlinden Lieve; De Clercq Pierre; Moras Dino; Bouillon Roger; Muñoz Alberto; Verstuyf Annemieke
Superagonistic fluorinated vitamin D3 analogs stabilize helix 12 of the vitamin D receptor.
Chemistry & biology 2008;15(10):1029-34.
2008: Shimizu Satoru; Juan Ella Czarina Magat; Miyashita Yu Ichiro; Sato Yoshiteru; Hoque Md Mominul; Suzuki Kaoru; Yogiashi Masataka; Tsunoda Masaru; Dock-Bregeon Anne Catherine; Moras Dino; Sekiguchi Takeshi; Takénaka Akio
Crystallization and preliminary crystallographic studies of putative threonyl-tRNA synthetases from Aeropyrum pernix and Sulfolobus tokodaii.
Acta crystallographica. Section F, Structural biology and crystallization communications 2008;64(Pt 10):903-10.
2008: Bovet Cédric; Ruff Marc; Eiler Sylvia; Granger Florence; Wenzel Ryan; Nazabal Alexis; Moras Dino; Zenobi Renato
Monitoring ligand modulation of protein-protein interactions by mass spectrometry: estrogen receptor alpha-SRC1.
Analytical chemistry 2008;80(20):7833-9.
2008: Greschik Holger; Althage Magnus; Flaig Ralf; Sato Yoshiteru; Chavant Virginie; Peluso-Iltis Carole; Choulier Laurence; Cronet Philippe; Rochel Natacha; Schüle Roland; Strömstedt Per-Erik; Moras Dino
Communication between the ERRalpha homodimer interface and the PGC-1alpha binding surface via the helix 8-9 loop.
The Journal of biological chemistry 2008;283(29):20220-30.
2008: Hourai Shinji; Rodrigues Luis Cezar; Antony Pierre; Reina-San-Martin Bernardo; Ciesielski Fabrice; Magnier Benjamin Claude; Schoonjans Kristina; Mouriño Antonio; Rochel Natacha; Moras Dino
Structure-based design of a superagonist ligand for the vitamin D nuclear receptor.
Chemistry & biology 2008;15(4):383-92.
2008: Busso Didier; Stierlé Matthieu; Thierry Jean-Claude; Moras Dino
A comparison of inoculation methods to simplify recombinant protein expression screening in Escherichia coli.
BioTechniques 2008;44(1):101-6.
2008: Cura Vincent; Gangloff Monique; Eiler Sylvia; Moras Dino; Ruff Marc
Cleaved thioredoxin fusion protein enables the crystallization of poorly soluble ERalpha in complex with synthetic ligands.
Acta crystallographica. Section F, Structural biology and crystallization communications 2008;64(Pt 1):54-7.
2008: Busso Didier; Thierry Jean-Claude; Moras Dino
The structural biology and genomics platform in strasbourg: an overview.
Methods in molecular biology (Clifton, N.J.) 2008;426():523-36.
2008: Busso Didier; Stierlé Matthieu; Thierry Jean-Claude; Moras Dino
Automated recombinant protein expression screening in Escherichia coli.
Methods in molecular biology (Clifton, N.J.) 2008;426():175-86.
2007: Browning Christopher; Martin Elyette; Loch Caroline; Wurtz Jean-Marie; Moras Dino; Stote Roland H; Dejaegere Annick P; Billas Isabelle M L
Critical role of desolvation in the binding of 20-hydroxyecdysone to the ecdysone receptor.
The Journal of biological chemistry 2007;282(45):32924-34.
2007: Troffer-Charlier Nathalie; Cura Vincent; Hassenboehler Pierre; Moras Dino; Cavarelli Jean
Functional insights from structures of coactivator-associated arginine methyltransferase 1 domains.
The EMBO journal 2007;26(20):4391-401.
2007: Büttner Matthias W; Burschka Christian; Daiss Jürgen O; Ivanova Diana; Rochel Natacha; Kammerer Sabrina; Peluso-Iltis Carole; Bindler Audrey; Gaudon Claudine; Germain Pierre; Moras Dino; Gronemeyer Hinrich; Tacke Reinhold
Silicon analogues of the retinoid agonists TTNPB and 3-methyl-TTNPB, disila-TTNPB and disila-3-methyl-TTNPB: chemistry and biology.
Chembiochem : a European journal of chemical biology 2007;8(14):1688-99.
2007: Iwema Thomas; Billas Isabelle M L; Beck Yannick; Bonneton François; Nierengarten Hélène; Chaumot Arnaud; Richards Geoff; Laudet Vincent; Moras Dino
Structural and functional characterization of a novel type of ligand-independent RXR-USP receptor.
The EMBO journal 2007;26(16):3770-82.
2007: Sun Kai; Montana Vedrana; Chellappa Karthikeyani; Brelivet Yann; Moras Dino; Maeda Yutaka; Parpura Vladimir; Paschal Bryce M; Sladek Frances M
Phosphorylation of a conserved serine in the deoxyribonucleic acid binding domain of nuclear receptors alters intracellular localization.
Molecular endocrinology (Baltimore, Md.) 2007;21(6):1297-311.
2007: Bovet Cédric; Wortmann Arno; Eiler Sylvia; Granger Florence; Ruff Marc; Gerrits Bertran; Moras Dino; Zenobi Renato
Estrogen receptor-ligand complexes measured by chip-based nanoelectrospray mass spectrometry: an approach for the screening of endocrine disruptors.
Protein science : a publication of the Protein Society 2007;16(5):938-46.
2007: Romier Christophe; James Nicole; Birck Catherine; Cavarelli Jean; Vivarès Christian; Collart Martine A; Moras Dino
Crystal structure, biochemical and genetic characterization of yeast and E. cuniculi TAF(II)5 N-terminal domain: implications for TFIID assembly.
Journal of molecular biology 2007;368(5):1292-306.
2007: Troffer-Charlier Nathalie; Cura Vincent; Hassenboehler Pierre; Moras Dino; Cavarelli Jean
Expression, purification, crystallization and preliminary crystallographic study of isolated modules of the mouse coactivator-associated arginine methyltransferase 1.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 4):330-3.
2007: Vitorino Marc; Coin Frédéric; Zlobinskaya Olga; Atkinson R Andrew; Moras Dino; Egly Jean-Marc; Poterszman Arnaud; Kieffer Bruno
Solution structure and self-association properties of the p8 TFIIH subunit responsible for trichothiodystrophy.
Journal of molecular biology 2007;368(2):473-80.
2007: Rochel Natacha; Hourai Shinji; Pérez-García Xenxo; Rumbo Antonio; Mourino Antonio; Moras Dino
Crystal structure of the vitamin D nuclear receptor ligand binding domain in complex with a locked side chain analog of calcitriol.
Archives of biochemistry and biophysics 2007;460(2):172-6.
2007: Lupien Mathieu; Jeyakumar M; Hébert Elise; Hilmi Khalid; Cotnoir-White David; Loch Caroline; Auger Anick; Dayan Guila; Pinard Geneviève-Anne; Wurtz Jean-Marie; Moras Dino; Katzenellenbogen John; Mader Sylvie
Raloxifene and ICI182,780 increase estrogen receptor-alpha association with a nuclear compartment via overlapping sets of hydrophobic amino acids in activation function 2 helix 12.
Molecular endocrinology (Baltimore, Md.) 2007;21(4):797-816.
2007: Ciesielski Fabrice; Rochel Natacha; Moras Dino
Adaptability of the Vitamin D nuclear receptor to the synthetic ligand Gemini: remodelling the LBP with one side chain rotation.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):235-42.
2007: Yokoyama Shigeyuki; Terwilliger Thomas C; Kuramitsu Seiki; Moras Dino; Sussman Joel L
RIKEN aids international structural genomics efforts.
Nature 2007;445(7123):21.
2006: Yusupova Gulnara; Jenner Lasse; Rees Bernard; Moras Dino; Yusupov Marat
Structural basis for messenger RNA movement on the ribosome.
Nature 2006;444(7117):391-4.
2006: Oblak Marko; Grdadolnik Simona Golic; Kotnik Miha; Poterszman Arnaud; Atkinson R Andrew; Nierengarten Helene; Desplancq Dominique; Moras Dino; Solmajer Tom
Biophysical characterization of an indolinone inhibitor in the ATP-binding site of DNA gyrase.
Biochemical and biophysical research communications 2006;349(4):1206-13.
2006: Romier Christophe; Ben Jelloul Marouane; Albeck Shira; Buchwald Gretel; Busso Didier; Celie Patrick H N; Christodoulou Evangelos; De Marco Valeria; van Gerwen Suzan; Knipscheer Puck; Lebbink Joyce H; Notenboom Valerie; Poterszman Arnaud; Rochel Natacha; Cohen Serge X; Unger Tamar; Sussman Joel L; Moras Dino; Sixma Titia K; Perrakis Anastassis
Co-expression of protein complexes in prokaryotic and eukaryotic hosts: experimental procedures, database tracking and case studies.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 10):1232-42.
2006: Banci L; Bertini I; Cusack S; de Jong R N; Heinemann U; Jones E Y; Kozielski F; Maskos K; Messerschmidt A; Owens R; Perrakis A; Poterszman A; Schneider G; Siebold C; Silman I; Sixma T; Stewart-Jones G; Sussman J L; Thierry J C; Moras Dino
First steps towards effective methods in exploiting high-throughput technologies for the determination of human protein structures of high biomedical value.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 10):1208-17.
2006: Hourai Shinji; Fujishima Toshie; Kittaka Atsushi; Suhara Yoshitomo; Takayama Hiroaki; Rochel Natacha; Moras Dino
Probing a water channel near the A-ring of receptor-bound 1 alpha,25-dihydroxyvitamin D3 with selected 2 alpha-substituted analogues.
Journal of medicinal chemistry 2006;49(17):5199-205.
2006: Gaillard Emilie; Bruck Nathalie; Brelivet Yann; Bour Gaétan; Lalevée Sébastien; Bauer Annie; Poch Olivier; Moras Dino; Rochette-Egly Cécile
Phosphorylation by PKA potentiates retinoic acid receptor alpha activity by means of increasing interaction with and phosphorylation by cyclin H/cdk7.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(25):9548-53.
2006: Jawhari Anass; Uhring Muriel; De Carlo Sacha; Crucifix Corinne; Tocchini-Valentini Guiseppe; Moras Dino; Schultz Patrick; Poterszman Arnaud
Structure and oligomeric state of human transcription factor TFIIE.
EMBO reports 2006;7(5):500-5.
2006: Olieric Natacha; Bey Gilbert; Nierengarten Hélène; Wang En-Duo; Moras Dino; Eriani Gilbert; Cavarelli Jean
Expression, purification, and characterization of a new heterotetramer structure of leucyl-tRNA synthetase from Aquifex aeolicus in Escherichia coli.
Protein expression and purification 2006;47(1):1-9.
2006: Shah Salimuddin; Islam Md Naimul; Dakshanamurthy Sivanesan; Rizvi Imran; Rao Mahadev; Herrell Roger; Zinser Glendon; Valrance Meggan; Aranda Ana; Moras Dino; Norman Anthony; Welsh JoEllen; Byers Stephen W
The molecular basis of vitamin D receptor and beta-catenin crossregulation.
Molecular cell 2006;21(6):799-809.
2006: González-Avión Xosé C; Mouriño Antonio; Rochel Natacha; Moras Dino
Novel 1alpha,25-dihydroxyvitamin D3 analogues with the side chain at C12.
Journal of medicinal chemistry 2006;49(5):1509-16.
2006: Syakhovich Vitaly E; Saraswathi N T; Ruff Marc; Bokut Sergey B; Moras Dino
Crystallization and preliminary crystallographic analysis of human glycosylated haemoglobin.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 2):106-9.
2006: Werten Sebastiaan; Moras Dino
A global transcription cofactor bound to juxtaposed strands of unwound DNA.
Nature structural & molecular biology 2006;13(2):181-2.
2006: Rochel Natacha; Moras Dino
Ligand binding domain of vitamin D receptors.
Current topics in medicinal chemistry 2006;6(12):1229-41.
2005: Uhring Muriel; Bey Gilbert; Lecompte Odile; Cavarelli Jean; Moras Dino; Poch Olivier
Cloning, purification and crystallization of a Walker-type Pyrococcus abyssi ATPase family member.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 10):925-7.
2005: Cura Vincent; Olieric Natacha; Guichard Alexandre; Wang En-Duo; Moras Dino; Eriani Gilbert; Cavarelli Jean
Crystallization and preliminary X-ray crystallographic study of the wild type and two mutants of the CP1 hydrolytic domain from Aquifex aeolicus leucyl-tRNA synthetase.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 10):899-901.
2005: Busso Didier; Delagoutte-Busso Bénédicte; Moras Dino
Construction of a set Gateway-based destination vectors for high-throughput cloning and expression screening in Escherichia coli.
Analytical biochemistry 2005;343(2):313-21.
2005: Kellenberger Esther; Dominguez Cyril; Fribourg Sébastien; Wasielewski Emeric; Moras Dino; Poterszman Arnaud; Boelens Rolf; Kieffer Bruno
Solution structure of the C-terminal domain of TFIIH P44 subunit reveals a novel type of C4C4 ring domain involved in protein-protein interactions.
The Journal of biological chemistry 2005;280(21):20785-92.
2005: Eelen Guy; Verlinden Lieve; Rochel Natacha; Claessens Frank; De Clercq Pierre; Vandewalle Maurits; Tocchini-Valentini Giuseppe; Moras Dino; Bouillon Roger; Verstuyf Annemieke
Superagonistic action of 14-epi-analogs of 1,25-dihydroxyvitamin D explained by vitamin D receptor-coactivator interaction.
Molecular pharmacology 2005;67(5):1566-73.
2005: Flaig Ralf; Greschik Holger; Peluso-Iltis Carole; Moras Dino
Structural basis for the cell-specific activities of the NGFI-B and the Nurr1 ligand-binding domain.
The Journal of biological chemistry 2005;280(19):19250-8.
2005: Jenner Lasse; Romby Pascale; Rees Bernard; Schulze-Briese Clemens; Springer Mathias; Ehresmann Chantal; Ehresmann Bernard; Moras Dino; Yusupova Gulnara; Yusupov Marat
Translational operator of mRNA on the ribosome: how repressor proteins exclude ribosome binding.
Science (New York, N.Y.) 2005;308(5718):120-3.
2005: Pillon Arnaud; Boussioux Anne-Marie; Escande Aurélie; Aït-Aïssa Sélim; Gomez Elena; Fenet Hélène; Ruff Marc; Moras Dino; Vignon Françoise; Duchesne Marie-Josèphe; Casellas Claude; Nicolas Jean-Claude; Balaguer Patrick
Binding of estrogenic compounds to recombinant estrogen receptor-alpha: application to environmental analysis.
Environmental health perspectives 2005;113(3):278-84.
2005: Klein Fabrice A C; Atkinson R Andrew; Potier Noelle; Moras Dino; Cavarelli Jean
Biochemical and NMR mapping of the interface between CREB-binding protein and ligand binding domains of nuclear receptor: beyond the LXXLL motif.
The Journal of biological chemistry 2005;280(7):5682-92.
2005: Billas Isabelle M L; Moras Dino
Ligand-binding pocket of the ecdysone receptor.
Vitamins and hormones 2005;73():101-29.
2005: Busso Didier; Poussin-Courmontagne Pierre; Rosé David; Ripp Raymond; Litt Alain; Thierry Jean-Claude; Moras Dino
Structural genomics of eukaryotic targets at a laboratory scale.
Journal of structural and functional genomics 2005;6(2-3):81-8.
2005: Thompson Julie D; Holbrook Stephen R; Katoh Kazutaka; Koehl Patrice; Moras Dino; Westhof Eric; Poch Olivier
MAO: a Multiple Alignment Ontology for nucleic acid and protein sequences.
Nucleic acids research 2005;33(13):4164-71.
2004: Sanglier Sarah; Bourguet William; Germain Pierre; Chavant Virginie; Moras Dino; Gronemeyer Hinrich; Potier Noelle; Van Dorsselaer Alain
Monitoring ligand-mediated nuclear receptor-coregulator interactions by noncovalent mass spectrometry.
European journal of biochemistry / FEBS 2004;271(23-24):4958-67.
2004: Jawhari Anass; Boussert Stéphanie; Lamour Valérie; Atkinson R Andrew; Kieffer Bruno; Poch Olivier; Potier Noelle; van Dorsselaer Alain; Moras Dino; Poterszman Arnaud
Domain architecture of the p62 subunit from the human transcription/repair factor TFIIH deduced by limited proteolysis and mass spectrometry analysis.
Biochemistry 2004;43(45):14420-30.
2004: Dock-Bregeon Anne-Catherine; Rees Bernard; Torres-Larios Alfredo; Bey Gilbert; Caillet Joel; Moras Dino
Achieving error-free translation; the mechanism of proofreading of threonyl-tRNA synthetase at atomic resolution.
Molecular cell 2004;16(3):375-86.
2004: Kammerer Sabrina; Germain Pierre; Flaig Ralf; Peluso-Iltis Carole; Mitschler André; Rochel Natacha; Gronemeyer Hinrich; Moras Dino
RARbeta ligand-binding domain bound to an SRC-1 co-activator peptide: purification, crystallization and preliminary X-ray diffraction analysis.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 11):2048-50.
2004: Tuynder Marcel; Fiucci Giusy; Prieur Sylvie; Lespagnol Alexandra; Géant Anne; Beaucourt Séverine; Duflaut Dominique; Besse Stéphanie; Susini Laurent; Cavarelli Jean; Moras Dino; Amson Robert; Telerman Adam
Translationally controlled tumor protein is a target of tumor reversion.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(43):15364-9.
2004: Mizwicki Mathew T; Keidel Don; Bula Craig M; Bishop June E; Zanello Laura P; Wurtz Jean-Marie; Moras Dino; Norman Anthony W
Identification of an alternative ligand-binding pocket in the nuclear vitamin D receptor and its functional importance in 1alpha,25(OH)2-vitamin D3 signaling.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(35):12876-81.
2004: Greschik Holger; Flaig Ralf; Renaud Jean-Paul; Moras Dino
Structural basis for the deactivation of the estrogen-related receptor gamma by diethylstilbestrol or 4-hydroxytamoxifen and determinants of selectivity.
The Journal of biological chemistry 2004;279(32):33639-46.
2004: Howard E I; Sanishvili R; Cachau R E; Mitschler A; Chevrier B; Barth P; Lamour V; Van Zandt M; Sibley E; Bon C; Moras D; Schneider T R; Joachimiak A; Podjarny A
Ultrahigh resolution drug design I: details of interactions in human aldose reductase-inhibitor complex at 0.66 A.
Proteins 2004;55(4):792-804.
2004: Ciesielski Fabrice; Rochel Natacha; Mitschler Andre; Kouzmenko Alexander; Moras Dino
Structural investigation of the ligand binding domain of the zebrafish VDR in complexes with 1alpha,25(OH)2D3 and Gemini: purification, crystallization and preliminary X-ray diffraction analysis.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):55-9.
2004: Brelivet Yann; Kammerer Sabrina; Rochel Natacha; Poch Olivier; Moras Dino
Signature of the oligomeric behaviour of nuclear receptors at the sequence and structural level.
EMBO reports 2004;5(4):423-9.
2004: Tocchini-Valentini Giuseppe; Rochel Natacha; Wurtz Jean-Marie; Moras Dino
Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification.
Journal of medicinal chemistry 2004;47(8):1956-61.
2003: Cans Christophe; Passer Brent J; Shalak Vyacheslav; Nancy-Portebois Vanessa; Crible Virginie; Amzallag Nathalie; Allanic David; Tufino Rowena; Argentini Manuela; Moras Dino; Fiucci Giusy; Goud Bruno; Mirande Marc; Amson Robert; Telerman Adam
Translationally controlled tumor protein acts as a guanine nucleotide dissociation inhibitor on the translation elongation factor eEF1A.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(24):13892-7.
2003: Billas Isabelle M L; Iwema Thomas; Garnier Jean-Marie; Mitschler André; Rochel Natacha; Moras Dino
Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor.
Nature 2003;426(6962):91-6.
2003: Sifaoui Farid; Lamour Valérie; Varon Emmanuelle; Moras Dino; Gutmann Laurent
ATP-bound conformation of topoisomerase IV: a possible target for quinolones in Streptococcus pneumoniae.
Journal of bacteriology 2003;185(20):6137-46.
2003: Stehlin-Gaon Catherine; Willmann Dominica; Zeyer Denis; Sanglier Sarah; Van Dorsselaer Alain; Renaud Jean-Paul; Moras Dino; Schüle Roland
All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta.
Nature structural biology 2003;10(10):820-5.
2003: Torres-Larios Alfredo; Sankaranarayanan Rajan; Rees Bernard; Dock-Bregeon Anne Catherine; Moras Dino
Conformational movements and cooperativity upon amino acid, ATP and tRNA binding in threonyl-tRNA synthetase.
Journal of molecular biology 2003;331(1):201-11.
2003: Potier Noelle; Billas Isabelle M L; Steinmetz Anke; Schaeffer Christine; van Dorsselaer Alain; Moras Dino; Renaud Jean-Paul
Using nondenaturing mass spectrometry to detect fortuitous ligands in orphan nuclear receptors.
Protein science : a publication of the Protein Society 2003;12(4):725-33.
2003: Choi Mihwa; Yamamoto Keiko; Itoh Toshimasa; Makishima Makoto; Mangelsdorf David J; Moras Dino; DeLuca Hector F; Yamada Sachiko
Interaction between vitamin D receptor and vitamin D ligands: two-dimensional alanine scanning mutational analysis.
Chemistry & biology 2003;10(3):261-70.
2003: Gall Anne-Laure; Ruff Marc; Moras Dino
The dual role of CHAPS in the crystallization of stromelysin-3 catalytic domain.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 3):603-6.
2003: Romier Christophe; Cocchiarella Fabienne; Mantovani Roberto; Moras Dino
The NF-YB/NF-YC structure gives insight into DNA binding and transcription regulation by CCAAT factor NF-Y.
The Journal of biological chemistry 2003;278(2):1336-45.
2003: Greschik Holger; Moras Dino
Structure-activity relationship of nuclear receptor-ligand interactions.
Current topics in medicinal chemistry 2003;3(14):1573-99.
2002: Lecompte Odile; Ripp Raymond; Thierry Jean-Claude; Moras Dino; Poch Olivier
Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale.
Nucleic acids research 2002;30(24):5382-90.
2002: Werten Sebastiaan; Mitschler André; Romier Christophe; Gangloff Yann-Gaël; Thuault Sylvie; Davidson Irwin; Moras Dino
Crystal structure of a subcomplex of human transcription factor TFIID formed by TATA binding protein-associated factors hTAF4 (hTAF(II)135) and hTAF12 (hTAF(II)20).
The Journal of biological chemistry 2002;277(47):45502-9.
2002: Klaholz Bruno; Moras Dino
C-H...O hydrogen bonds in the nuclear receptor RARgamma--a potential tool for drug selectivity.
Structure (London, England : 1993) 2002;10(9):1197-204.
2002: Lamour V; Hoermann L; Jeltsch J M; Oudet P; Moras D
Crystallization of the 43 kDa ATPase domain of Thermus thermophilus gyrase B in complex with novobiocin.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 8):1376-8.
2002: Jawhari Anass; Lainé Jean-Philippe; Dubaele Sandy; Lamour Valérie; Poterszman Arnaud; Coin Frédéric; Moras Dino; Egly Jean-Marc
p52 Mediates XPB function within the transcription/repair factor TFIIH.
The Journal of biological chemistry 2002;277(35):31761-7.
2002: Lafitte Daniel; Lamour Valérie; Tsvetkov Philippe O; Makarov Alexander A; Klich Michel; Deprez Pierre; Moras Dino; Briand Claudette; Gilli Robert
DNA gyrase interaction with coumarin-based inhibitors: the role of the hydroxybenzoate isopentenyl moiety and the 5'-methyl group of the noviose.
Biochemistry 2002;41(23):7217-23.
2002: Egea Pascal F; Mitschler André; Moras Dino
Molecular recognition of agonist ligands by RXRs.
Molecular endocrinology (Baltimore, Md.) 2002;16(5):987-97.
2002: Torres-Larios Alfredo; Dock-Bregeon Anne-Catherine; Romby Pascale; Rees Bernard; Sankaranarayanan Rajan; Caillet Joel; Springer Mathias; Ehresmann Chantal; Ehresmann Bernard; Moras Dino
Structural basis of translational control by Escherichia coli threonyl tRNA synthetase.
Nature structural biology 2002;9(5):343-7.
2002: Lamour Valérie; Hoermann Laurence; Jeltsch Jean-Marc; Oudet Pierre; Moras Dino
An open conformation of the Thermus thermophilus gyrase B ATP-binding domain.
The Journal of biological chemistry 2002;277(21):18947-53.
2002: Troffer-Charlier Nathalie; Ogier Joëlle; Moras Dino; Cavarelli Jean
Crystal structure of the V-region of Streptococcus mutans antigen I/II at 2.4 A resolution suggests a sugar preformed binding site.
Journal of molecular biology 2002;318(1):179-88.
2002: Jawhari Anass; Uhring Muriel; Crucifix Corinne; Fribourg Sébastien; Schultz Patrick; Poterszman Arnaud; Egly Jean Marc; Moras Dino
Expression of FLAG fusion proteins in insect cells: application to the multi-subunit transcription/DNA repair factor TFIIH.
Protein expression and purification 2002;24(3):513-23.
2002: Greschik Holger; Wurtz Jean-Marie; Sanglier Sarah; Bourguet William; van Dorsselaer Alain; Moras Dino; Renaud Jean-Paul
Structural and functional evidence for ligand-independent transcriptional activation by the estrogen-related receptor 3.
Molecular cell 2002;9(2):303-13.
2002: Frontini Mattia; Imbriano Carol; diSilvio Alberto; Bell Brendan; Bogni Alessia; Romier Christophe; Moras Dino; Tora Laszlo; Davidson Irwin; Mantovani Roberto
NF-Y recruitment of TFIID, multiple interactions with histone fold TAF(II)s.
The Journal of biological chemistry 2002;277(8):5841-8.
2002: Sasorith Souphatta; Billas Isabelle M L; Iwema Thomas; Moras Dino; Wurtz Jean-Marie
Structure-based analysis of the ultraspiracle protein and docking studies of putative ligands.
Journal of insect science (Online) 2002;2():25.
2001: Stehlin C; Wurtz J M; Steinmetz A; Greiner E; Schüle R; Moras D; Renaud J P
X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation.
The EMBO journal 2001;20(21):5822-31.
2001: Rocchi S; Picard F; Vamecq J; Gelman L; Potier N; Zeyer D; Dubuquoy L; Bac P; Champy M F; Plunket K D; Leesnitzer L M; Blanchard S G; Desreumaux P; Moras D; Renaud J P; Auwerx J
A unique PPARgamma ligand with potent insulin-sensitizing yet weak adipogenic activity.
Molecular cell 2001;8(4):737-47.
2001: Moulinier L; Eiler S; Eriani G; Gangloff J; Thierry J C; Gabriel K; McClain W H; Moras D
The structure of an AspRS-tRNA(Asp) complex reveals a tRNA-dependent control mechanism.
The EMBO journal 2001;20(18):5290-301.
2001: Eiler S; Gangloff M; Duclaud S; Moras D; Ruff M
Overexpression, purification, and crystal structure of native ER alpha LBD.
Protein expression and purification 2001;22(2):165-73.
2001: Tocchini-Valentini G; Rochel N; Wurtz J M; Mitschler A; Moras D
Crystal structures of the vitamin D receptor complexed to superagonist 20-epi ligands.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(10):5491-6.
2001: Gangloff M; Ruff M; Eiler S; Duclaud S; Wurtz J M; Moras D
Crystal structure of a mutant hERalpha ligand-binding domain reveals key structural features for the mechanism of partial agonism.
The Journal of biological chemistry 2001;276(18):15059-65.
2001: Gall A L; Ruff M; Kannan R; Cuniasse P; Yiotakis A; Dive V; Rio M C; Basset P; Moras D
Crystal structure of the stromelysin-3 (MMP-11) catalytic domain complexed with a phosphinic inhibitor mimicking the transition-state.
Journal of molecular biology 2001;307(2):577-86.
2001: Egea P F; Rochel N; Birck C; Vachette P; Timmins P A; Moras D
Effects of ligand binding on the association properties and conformation in solution of retinoic acid receptors RXR and RAR.
Journal of molecular biology 2001;307(2):557-76.
2001: Egea P F; Moras D
Purification and crystallization of the human RXRalpha ligand-binding domain-9-cisRA complex.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 3):434-7.
2001: Billas I M; Moulinier L; Rochel N; Moras D
Crystal structure of the ligand-binding domain of the ultraspiracle protein USP, the ortholog of retinoid X receptors in insects.
The Journal of biological chemistry 2001;276(10):7465-74.
2001: Fribourg S; Romier C; Werten S; Gangloff Y G; Poterszman A; Moras D
Dissecting the interaction network of multiprotein complexes by pairwise coexpression of subunits in E. coli.
Journal of molecular biology 2001;306(2):363-73.
2001: Rochel N; Tocchini-Valentini G; Egea P F; Juntunen K; Garnier J M; Vihko P; Moras D
Functional and structural characterization of the insertion region in the ligand binding domain of the vitamin D nuclear receptor.
European journal of biochemistry / FEBS 2001;268(4):971-9.
2001: Wurtz J M; Moras D
Molecular determinants for agonist and antagonist binding to steroid nuclear receptors.
Ernst Schering Research Foundation workshop 2001;(34):167-80.
2001: Steinmetz A C; Renaud J P; Moras D
Binding of ligands and activation of transcription by nuclear receptors.
Annual review of biophysics and biomolecular structure 2001;30():329-59.
2000: Dock-Bregeon A; Sankaranarayanan R; Romby P; Caillet J; Springer M; Rees B; Francklyn C S; Ehresmann C; Moras D
Transfer RNA-mediated editing in threonyl-tRNA synthetase. The class II solution to the double discrimination problem.
Cell 2000;103(6):877-84.
2000: Potier N; Lamour V; Poterszman A; Thierry J C; Moras D; Van Dorsselaer A
Characterization of crystal content by ESI-MS and MALDI-MS.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 12):1583-90.
2000: Renaud J P; Moras D
Structural studies on nuclear receptors.
Cellular and molecular life sciences : CMLS 2000;57(12):1748-69.
2000: Delagoutte B; Moras D; Cavarelli J
tRNA aminoacylation by arginyl-tRNA synthetase: induced conformations during substrates binding.
The EMBO journal 2000;19(21):5599-610.
2000: Auzou G; Fagart J; Souque A; Hellal-Lévy C; Wurtz J M; Moras D; Rafestin-Oblin M E
A single amino acid mutation of ala-773 in the mineralocorticoid receptor confers agonist properties to 11beta-substituted spirolactones.
Molecular pharmacology 2000;58(4):684-91.
2000: Fribourg S; Kellenberger E; Rogniaux H; Poterszman A; Van Dorsselaer A; Thierry J C; Egly J M; Moras D; Kieffer B
Structural characterization of the cysteine-rich domain of TFIIH p44 subunit.
The Journal of biological chemistry 2000;275(41):31963-71.
2000: Schultz P; Fribourg S; Poterszman A; Mallouh V; Moras D; Egly J M
Molecular structure of human TFIIH.
Cell 2000;102(5):599-607.
2000: Klaholz B P; Mitschler A; Moras D
Structural basis for isotype selectivity of the human retinoic acid nuclear receptor.
Journal of molecular biology 2000;302(1):155-70.
2000: Hellal-Levy C; Fagart J; Souque A; Wurtz J M; Moras D; Rafestin-Oblin M E
Crucial role of the H11-H12 loop in stabilizing the active conformation of the human mineralocorticoid receptor.
Molecular endocrinology (Baltimore, Md.) 2000;14(8):1210-21.
2000: Klaholz B P; Moras D
Structural role of a detergent molecule in retinoic acid nuclear receptor crystals.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 7):933-5.
2000: Bourguet W; Andry V; Iltis C; Klaholz B; Potier N; Van Dorsselaer A; Chambon P; Gronemeyer H; Moras D
Heterodimeric complex of RAR and RXR nuclear receptor ligand-binding domains: purification, crystallization, and preliminary X-ray diffraction analysis.
Protein expression and purification 2000;19(2):284-8.
2000: Wurtz J M; Guillot B; Fagart J; Moras D; Tietjen K; Schindler M
A new model for 20-hydroxyecdysone and dibenzoylhydrazine binding: a homology modeling and docking approach.
Protein science : a publication of the Protein Society 2000;9(6):1073-84.
2000: Sankaranarayanan R; Dock-Bregeon A C; Rees B; Bovee M; Caillet J; Romby P; Francklyn C S; Moras D
Zinc ion mediated amino acid discrimination by threonyl-tRNA synthetase.
Nature structural biology 2000;7(6):461-5.
2000: Egea P F; Klaholz B P; Moras D
Ligand-protein interactions in nuclear receptors of hormones.
FEBS letters 2000;476(1-2):62-7.
2000: Sauter C; Lorber B; Cavarelli J; Moras D; Giegé R
The free yeast aspartyl-tRNA synthetase differs from the tRNA(Asp)-complexed enzyme by structural changes in the catalytic site, hinge region, and anticodon-binding domain.
Journal of molecular biology 2000;299(5):1313-24.
2000: Briand C; Poterszman A; Eiler S; Webster G; Thierry J; Moras D
An intermediate step in the recognition of tRNA(Asp) by aspartyl-tRNA synthetase.
Journal of molecular biology 2000;299(4):1051-60.
2000: Klaholz B P; Mitschler A; Belema M; Zusi C; Moras D
Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6322-7.
2000: Egea P F; Mitschler A; Rochel N; Ruff M; Chambon P; Moras D
Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid.
The EMBO journal 2000;19(11):2592-601.
2000: Calderone V; Chevrier B; Van Zandt M; Lamour V; Howard E; Poterszman A; Barth P; Mitschler A; Lu J; Dvornik D M; Klebe G; Kraemer O; Moorman A R; Moras D; Podjarny A
The structure of human aldose reductase bound to the inhibitor IDD384.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 5):536-40.
2000: Delagoutte B; Keith G; Moras D; Cavarelli J
Crystallization and preliminary X-ray crystallographic analysis of yeast arginyl-tRNA synthetase-yeast tRNAArg complexes.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 4):492-4.
2000: Brino L; Urzhumtsev A; Mousli M; Bronner C; Mitschler A; Oudet P; Moras D
Dimerization of Escherichia coli DNA-gyrase B provides a structural mechanism for activating the ATPase catalytic center.
The Journal of biological chemistry 2000;275(13):9468-75.
2000: Bourguet W; Vivat V; Wurtz J M; Chambon P; Gronemeyer H; Moras D
Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains.
Molecular cell 2000;5(2):289-98.
2000: Rochel N; Wurtz J M; Mitschler A; Klaholz B; Moras D
The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand.
Molecular cell 2000;5(1):173-9.
2000: Gangloff Y G; Werten S; Romier C; Carré L; Poch O; Moras D; Davidson I
The human TFIID components TAF(II)135 and TAF(II)20 and the yeast SAGA components ADA1 and TAF(II)68 heterodimerize to form histone-like pairs.
Molecular and cellular biology 2000;20(1):340-51.
1999: Juntunen K; Rochel N; Moras D; Vihko P
Large-scale expression and purification of the human vitamin D receptor and its ligand-binding domain for structural studies.
The Biochemical journal 1999;344 Pt 2():297-303.
1999: Eiler S; Dock-Bregeon A; Moulinier L; Thierry J C; Moras D
Synthesis of aspartyl-tRNA(Asp) in Escherichia coli--a snapshot of the second step.
The EMBO journal 1999;18(22):6532-41.
1999: Dantonel J C; Wurtz J M; Poch O; Moras D; Tora L
The TBP-like factor: an alternative transcription factor in metazoa?
Trends in biochemical sciences 1999;24(9):335-9.
1999: Blondel A; Renaud J P; Fischer S; Moras D; Karplus M
Retinoic acid receptor: a simulation analysis of retinoic acid binding and the resulting conformational changes.
Journal of molecular biology 1999;291(1):101-15.
1999: Géhin M; Vivat V; Wurtz J M; Losson R; Chambon P; Moras D; Gronemeyer H
Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists.
Chemistry & biology 1999;6(8):519-29.
1999: Rogniaux H; Van Dorsselaer A; Barth P; Biellmann J F; Barbanton J; van Zandt M; Chevrier B; Howard E; Mitschler A; Potier N; Urzhumtseva L; Moras D; Podjarny A
Binding of aldose reductase inhibitors: correlation of crystallographic and mass spectrometric studies.
Journal of the American Society for Mass Spectrometry 1999;10(7):635-47.
1999: Lavigne A C; Gangloff Y G; Carré L; Mengus G; Birck C; Poch O; Romier C; Moras D; Davidson I
Synergistic transcriptional activation by TATA-binding protein and hTAFII28 requires specific amino acids of the hTAFII28 histone fold.
Molecular and cellular biology 1999;19(7):5050-60.
1999: Ador L; Camasses A; Erbs P; Cavarelli J; Moras D; Gangloff J; Eriani G
Active site mapping of yeast aspartyl-tRNA synthetase by in vivo selection of enzyme mutations lethal for cell growth.
Journal of molecular biology 1999;288(2):231-42.
1999: Sankaranarayanan R; Dock-Bregeon A C; Romby P; Caillet J; Springer M; Rees B; Ehresmann C; Ehresmann B; Moras D
The structure of threonyl-tRNA synthetase-tRNA(Thr) complex enlightens its repressor activity and reveals an essential zinc ion in the active site.
Cell 1999;97(3):371-81.
1999: Lamour V; Barth P; Rogniaux H; Poterszman A; Howard E; Mitschler A; Van Dorsselaer A; Podjarny A; Moras D
Production of crystals of human aldose reductase with very high resolution diffraction.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 3):721-3.
1999: Arnez J G; Dock-Bregeon A C; Moras D
Glycyl-tRNA synthetase uses a negatively charged pit for specific recognition and activation of glycine.
Journal of molecular biology 1999;286(5):1449-59.
1999: Sauter C; Lorber B; Kern D; Cavarelli J; Moras D; Giegé R
Crystallogenesis studies on yeast aspartyl-tRNA synthetase: use of phase diagram to improve crystal quality.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 1):149-56.
1999: Greschik H; Wurtz J M; Hublitz P; Köhler F; Moras D; Schüle R
Characterization of the DNA-binding and dimerization properties of the nuclear orphan receptor germ cell nuclear factor.
Molecular and cellular biology 1999;19(1):690-703.
1998: Briand C; Poterszman A; Mitschler A; Yusupov M; Thierry J C; Moras D
Crystals of Thermus thermophilus tRNAAsp complexed with its cognate aspartyl-tRNA synthetase have a solvent content of 75%. Comparison with other aminoacylation systems.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 6 Pt 2):1382-6.
1998: Cavarelli J; Delagoutte B; Eriani G; Gangloff J; Moras D
L-arginine recognition by yeast arginyl-tRNA synthetase.
The EMBO journal 1998;17(18):5438-48.
1998: Schmitt E; Moulinier L; Fujiwara S; Imanaka T; Thierry J C; Moras D
Crystal structure of aspartyl-tRNA synthetase from Pyrococcus kodakaraensis KOD: archaeon specificity and catalytic mechanism of adenylate formation.
The EMBO journal 1998;17(17):5227-37.
1998: Arnez J G; Flanagan K; Moras D; Simonson T
Engineering and Mg2+ site to replace a structurally conserved arginine in the catalytic center of histidyl-tRNA synthetase by computer experiments.
Proteins 1998;32(3):362-80.
1998: Birck C; Poch O; Romier C; Ruff M; Mengus G; Lavigne A C; Davidson I; Moras D
Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family.
Cell 1998;94(2):239-49.
1998: Fagart J; Wurtz J M; Souque A; Hellal-Levy C; Moras D; Rafestin-Oblin M E
Antagonism in the human mineralocorticoid receptor.
The EMBO journal 1998;17(12):3317-25.
1998: Wurtz J M; Egner U; Heinrich N; Moras D; Mueller-Fahrnow A
Three-dimensional models of estrogen receptor ligand binding domain complexes, based on related crystal structures and mutational and structure-activity relationship data.
Journal of medicinal chemistry 1998;41(11):1803-14.
1998: Klaholz B P; Renaud J P; Mitschler A; Zusi C; Chambon P; Gronemeyer H; Moras D
Conformational adaptation of agonists to the human nuclear receptor RAR gamma.
Nature structural biology 1998;5(3):199-202.
1998: Archontis G; Simonson T; Moras D; Karplus M
Specific amino acid recognition by aspartyl-tRNA synthetase studied by free energy simulations.
Journal of molecular biology 1998;275(5):823-46.
1998: Davidson I; Romier C; Lavigne A C; Birck C; Mengus G; Poch O; Moras D
Functional and structural analysis of the subunits of human transcription factor TFIID.
Cold Spring Harbor symposia on quantitative biology 1998;63():233-41.
1997: Lalli E; Bardoni B; Zazopoulos E; Wurtz J M; Strom T M; Moras D; Sassone-Corsi P
A transcriptional silencing domain in DAX-1 whose mutation causes adrenal hypoplasia congenita.
Molecular endocrinology (Baltimore, Md.) 1997;11(13):1950-60.
1997: Vichi P; Coin F; Renaud J P; Vermeulen W; Hoeijmakers J H; Moras D; Egly J M
Cisplatin- and UV-damaged DNA lure the basal transcription factor TFIID/TBP.
The EMBO journal 1997;16(24):7444-56.
1997: Poterszman A; Lamour V; Egly J M; Moras D; Thierry J C; Poch O
A eukaryotic XPB/ERCC3-like helicase in Mycobacterium leprae?
Trends in biochemical sciences 1997;22(11):418-9.
1997: Vivat V; Zechel C; Wurtz J M; Bourguet W; Kagechika H; Umemiya H; Shudo K; Moras D; Gronemeyer H; Chambon P
A mutation mimicking ligand-induced conformational change yields a constitutive RXR that senses allosteric effects in heterodimers.
The EMBO journal 1997;16(18):5697-709.
1997: Mayer-Jung C; Moras D; Timsit Y
Effect of cytosine methylation on DNA-DNA recognition at CpG steps.
Journal of molecular biology 1997;270(3):328-35.
1997: Arnez J G; Augustine J G; Moras D; Francklyn C S
The first step of aminoacylation at the atomic level in histidyl-tRNA synthetase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(14):7144-9.
1997: Cavarelli J; Prévost G; Bourguet W; Moulinier L; Chevrier B; Delagoutte B; Bilwes A; Mourey L; Rifai S; Piémont Y; Moras D
The structure of Staphylococcus aureus epidermolytic toxin A, an atypic serine protease, at 1.7 A resolution.
Structure (London, England : 1993) 1997;5(6):813-24.
1997: Arnez J G; Moras D
Structural and functional considerations of the aminoacylation reaction.
Trends in biochemical sciences 1997;22(6):211-6.
1997: Martin F; Sharples G J; Lloyd R G; Eiler S; Moras D; Gangloff J; Eriani G
Characterization of a thermosensitive Escherichia coli aspartyl-tRNA synthetase mutant.
Journal of bacteriology 1997;179(11):3691-6.
1997: Urzhumtsev A; Tête-Favier F; Mitschler A; Barbanton J; Barth P; Urzhumtseva L; Biellmann J F; Podjarny A; Moras D
A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil.
Structure (London, England : 1993) 1997;5(5):601-12.
1997: Andersen G; Busso D; Poterszman A; Hwang J R; Wurtz J M; Ripp R; Thierry J C; Egly J M; Moras D
The structure of cyclin H: common mode of kinase activation and specific features.
The EMBO journal 1997;16(5):958-67.
1997: Rochel N; Renaud J P; Ruff M; Vivat V; Granger F; Bonnier D; Lerouge T; Chambon P; Gronemeyer H; Moras D
Purification of the human RARgamma ligand-binding domain and crystallization of its complex with all-trans retinoic acid.
Biochemical and biophysical research communications 1997;230(2):293-6.
1996: Andersen G; Poterszman A; Egly J M; Moras D; Thierry J C
The crystal structure of human cyclin H.
FEBS letters 1996;397(1):65-9.
1996: Schmitt E; Mechulam Y; Ruff M; Mitschler A; Moras D; Blanquet S
Crystallization and preliminary X-ray analysis of Escherichia coli methionyl-tRNA(fMet) formyltransferase.
Proteins 1996;25(1):139-41.
1996: Chevrier B; D'Orchymont H; Schalk C; Tarnus C; Moras D
The structure of the Aeromonas proteolytica aminopeptidase complexed with a hydroxamate inhibitor. Involvement in catalysis of Glu151 and two zinc ions of the co-catalytic unit.
European journal of biochemistry / FEBS 1996;237(2):393-8.
1996: Wurtz J M; Bourguet W; Renaud J P; Vivat V; Chambon P; Moras D; Gronemeyer H
A canonical structure for the ligand-binding domain of nuclear receptors.
Nature structural biology 1996;3(2):206.
1996: Boeglin M; Dock-Brégeon A C; Eriani G; Gangloff J; Ruff M; Poterszman A; Thierry J C; Moras D
Crystallization of Escherichia coli aspartyl-tRNA synthetase in its free state and in a complex with yeast tRNA(Asp).
Acta crystallographica. Section D, Biological crystallography 1996;52(Pt 1):211-4.
1996: Wurtz J M; Bourguet W; Renaud J P; Vivat V; Chambon P; Moras D; Gronemeyer H
A canonical structure for the ligand-binding domain of nuclear receptors.
Nature structural biology 1996;3(1):87-94.
1996: Rees B; Cavarelli J; Moras D
Conformational flexibility of tRNA: structural changes in yeast tRNA(Asp) upon binding to aspartyl-tRNA synthetase.
Biochimie 1996;78(7):624-31.
1996: Giegé R; Florentz C; Kern D; Gangloff J; Eriani G; Moras D
Aspartate identity of transfer RNAs.
Biochimie 1996;78(7):605-23.
1995: Renaud J P; Rochel N; Ruff M; Vivat V; Chambon P; Gronemeyer H; Moras D
Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid.
Nature 1995;378(6558):681-9.
1995: Bourguet W; Ruff M; Bonnier D; Granger F; Boeglin M; Chambon P; Moras D; Gronemeyer H
Purification, functional characterization, and crystallization of the ligand binding domain of the retinoid X receptor.
Protein expression and purification 1995;6(5):604-8.
1995: Cura V; Kern D; Mitschler A; Moras D
Crystallization of threonyl-tRNA synthetase from Thermus thermophilus and preliminary crystallographic data.
FEBS letters 1995;374(1):110-2.
1995: Timsit Y; Moras D
Self-fitting and self-modifying properties of the B-DNA molecule.
Journal of molecular biology 1995;251(5):629-47.
1995: Logan D T; Mazauric M H; Kern D; Moras D
Crystal structure of glycyl-tRNA synthetase from Thermus thermophilus.
The EMBO journal 1995;14(17):4156-67.
1995: Arnez J G; Harris D C; Mitschler A; Rees B; Francklyn C S; Moras D
Crystal structure of histidyl-tRNA synthetase from Escherichia coli complexed with histidyl-adenylate.
The EMBO journal 1995;14(17):4143-55.
1995: Bourguet W; Ruff M; Chambon P; Gronemeyer H; Moras D
Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha.
Nature 1995;375(6530):377-82.
1995: Eriani G; Cavarelli J; Martin F; Ador L; Rees B; Thierry J C; Gangloff J; Moras D
The class II aminoacyl-tRNA synthetases and their active site: evolutionary conservation of an ATP binding site.
Journal of molecular evolution 1995;40(5):499-508.
1995: Moras D; Poterszman A
RNA-protein interactions. Diverse modes of recognition.
Current biology : CB 1995;5(3):249-51.
1995: Tsunoda M; Takenaka A; Cavarelli J; Rees B; Thierry J C; Moras D
Electrostatic potential in aminoacylation by aspartyl-tRNAs synthetase.
Nucleic acids symposium series 1995;(34):65-6.
1994: Poterszman A; Delarue M; Thierry J C; Moras D
Synthesis and recognition of aspartyl-adenylate by Thermus thermophilus aspartyl-tRNA synthetase.
Journal of molecular biology 1994;244(2):158-67.
1994: Logan D T; Cura V; Touzel J P; Kern D; Moras D
Crystallisation of the glycyl-tRNA synthetase from Thermus thermophilus and initial crystallographic data.
Journal of molecular biology 1994;241(5):732-5.
1994: Francklyn C; Harris D; Moras D
Crystallization of histidyl-tRNA synthetase from Escherichia coli.
Journal of molecular biology 1994;241(2):275-7.
1994: Delarue M; Poterszman A; Nikonov S; Garber M; Moras D; Thierry J C
Crystal structure of a prokaryotic aspartyl tRNA-synthetase.
The EMBO journal 1994;13(14):3219-29.
1994: Bilwes A; Rees B; Moras D; Ménez R; Ménez A
X-ray structure at 1.55 A of toxin gamma, a cardiotoxin from Naja nigricollis venom. Crystal packing reveals a model for insertion into membranes.
Journal of molecular biology 1994;239(1):122-36.
1994: Chevrier B; Schalk C; D'Orchymont H; Rondeau J M; Moras D; Tarnus C
Crystal structure of Aeromonas proteolytica aminopeptidase: a prototypical member of the co-catalytic zinc enzyme family.
Structure (London, England : 1993) 1994;2(4):283-91.
1994: Cavarelli J; Eriani G; Rees B; Ruff M; Boeglin M; Mitschler A; Martin F; Gangloff J; Thierry J C; Moras D
The active site of yeast aspartyl-tRNA synthetase: structural and functional aspects of the aminoacylation reaction.
The EMBO journal 1994;13(2):327-37.
1993: Martin F; Eriani G; Eiler S; Moras D; Dirheimer G; Gangloff J
Overproduction and purification of native and queuine-lacking Escherichia coli tRNA(Asp). Role of the wobble base in tRNA(Asp) acylation.
Journal of molecular biology 1993;234(4):965-74.
1993: Eriani G; Cavarelli J; Martin F; Dirheimer G; Moras D; Gangloff J
Role of dimerization in yeast aspartyl-tRNA synthetase and importance of the class II invariant proline.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(22):10816-20.
1993: Delarue M; Moras D
The aminoacyl-tRNA synthetase family: modules at work.
BioEssays : news and reviews in molecular, cellular and developmental biology 1993;15(10):675-87.
1993: Keith G; Yusupov M; Briand C; Moras D; Kern D; Brion C [corrected to Briand C ]
Sequence of tRNA(Asp) from Thermus thermophilus HB8.
Nucleic acids research 1993;21(18):4399.
1993: Mourey L; Samama J P; Delarue M; Petitou M; Choay J; Moras D
Crystal structure of cleaved bovine antithrombin III at 3.2 A resolution.
Journal of molecular biology 1993;232(1):223-41.
1993: Poterszman A; Plateau P; Moras D; Blanquet S; Mazauric M H; Kreutzer R; Kern D
Sequence, overproduction and crystallization of aspartyl-tRNA synthetase from Thermus thermophilus. Implications for the structure of prokaryotic aspartyl-tRNA synthetases.
FEBS letters 1993;325(3):183-6.
1993: Tête-Favier F; Rondeau J M; Podjarny A; Moras D
Structure determination of aldose reductase: joys and traps of local symmetry averaging.
Acta crystallographica. Section D, Biological crystallography 1993;49(Pt 2):246-56.
1993: Cavarelli J; Rees B; Ruff M; Thierry J C; Moras D
Yeast tRNA(Asp) recognition by its cognate class II aminoacyl-tRNA synthetase.
Nature 1993;362(6416):181-4.
1993: Cavarelli J; Moras D
Recognition of tRNAs by aminoacyl-tRNA synthetases.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1993;7(1):79-86.
1993: Moras D
Structural aspects and evolutionary implications of the recognition between tRNAs and aminoacyl-tRNA synthetases.
Biochimie 1993;75(8):651-7.
1993: Cavarelli J; Rees B; Thierry J C; Moras D
Yeast aspartyl-tRNA synthetase: a structural view of the aminoacylation reaction.
Biochimie 1993;75(12):1117-23.
1992: Reshetnikova L; Chernaya M; Ankilova V; Lavrik O; Delarue M; Thierry J C; Moras D; Safro M
Three-dimensional structure of phenylalanyl-transfer RNA synthetase from Thermus thermophilus HB8 at 0.6-nm resolution.
European journal of biochemistry / FEBS 1992;208(2):411-7.
1992: Eiler S; Boeglin M; Martin F; Eriani G; Gangloff J; Thierry J C; Moras D
Crystallization of aspartyl-tRNA synthetase-tRNA(Asp) complex from Escherichia coli and first crystallographic results.
Journal of molecular biology 1992;224(4):1171-3.
1992: Schalk C; Remy J M; Chevrier B; Moras D; Tarnus C
Rapid purification of the Aeromonas proteolytica aminopeptidase: crystallization and preliminary X-ray data.
Archives of biochemistry and biophysics 1992;294(1):91-7.
1992: Rondeau J M; Tête-Favier F; Podjarny A; Reymann J M; Barth P; Biellmann J F; Moras D
Novel NADPH-binding domain revealed by the crystal structure of aldose reductase.
Nature 1992;355(6359):469-72.
1991: Timsit Y; Vilbois E; Moras D
Base-pairing shift in the major groove of (CA)n tracts by B-DNA crystal structures.
Nature 1991;354(6349):167-70.
1991: Timsit Y; Moras D
Groove-backbone interaction in B-DNA. Implication for DNA condensation and recombination.
Journal of molecular biology 1991;221(3):919-40.
1991: Yusupova G; Yusupov M; Spirin A; Ebel J P; Moras D; Ehresmann C; Ehresmann B
Formation and crystallization of Thermus thermophilus 70S ribosome/tRNA complexes.
FEBS letters 1991;290(1-2):69-72.
1991: Ruff M; Krishnaswamy S; Boeglin M; Poterszman A; Mitschler A; Podjarny A; Rees B; Thierry J C; Moras D
Class II aminoacyl transfer RNA synthetases: crystal structure of yeast aspartyl-tRNA synthetase complexed with tRNA(Asp).
Science (New York, N.Y.) 1991;252(5013):1682-9.
1991: Rondeau J M; Moras D; Tête F; Podjarny A; Van Dorsselaer A; Reymann J M; Barth P; Biellmann J F
Structural studies of pig lens aldose reductase: reversible dimerization of the enzyme.
Advances in experimental medicine and biology 1991;284():113-8.
1990: Eriani G; Delarue M; Poch O; Gangloff J; Moras D
Partition of tRNA synthetases into two classes based on mutually exclusive sets of sequence motifs.
Nature 1990;347(6289):203-6.
1990: Mourey L; Samama J P; Delarue M; Choay J; Lormeau J C; Petitou M; Moras D
Antithrombin III: structural and functional aspects.
Biochimie 1990;72(8):599-608.
1990: Rees B; Bilwes A; Samama J P; Moras D
Cardiotoxin VII4 from Naja mossambica mossambica. The refined crystal structure.
Journal of molecular biology 1990;214(1):281-97.
1990: Delarue M; Poch O; Tordo N; Moras D; Argos P
An attempt to unify the structure of polymerases.
Protein engineering 1990;3(6):461-7.
1989: Samama J P; Delarue M; Mourey L; Choay J; Moras D
Crystallization and preliminary crystallographic data for bovine antithrombin III.
Journal of molecular biology 1989;210(4):877-9.
1989: Timsit Y; Westhof E; Fuchs R P; Moras D
Unusual helical packing in crystals of DNA bearing a mutation hot spot.
Nature 1989;341(6241):459-62.
1989: Dock-Bregeon A C; Chevrier B; Podjarny A; Johnson J; de Bear J S; Gough G R; Gilham P T; Moras D
Crystallographic structure of an RNA helix: [U(UA)6A]2.
Journal of molecular biology 1989;209(3):459-74.
1989: Trakhanov S; Yusupov M; Shirokov V; Garber M; Mitschler A; Ruff M; Thierry J C; Moras D
Preliminary X-ray investigation of 70 S ribosome crystals from Thermus thermophilus.
Journal of molecular biology 1989;209(2):327-8.
1989: Rondeau J M; Cagnon C; Moras D; Masson J M
Crystallization and preliminary X-ray data of a phleomycin-binding protein from Streptoalloteichus hindustanus.
Journal of molecular biology 1989;207(3):645-6.
1988: Altschuh D; Vernet T; Berti P; Moras D; Nagai K
Coordinated amino acid changes in homologous protein families.
Protein engineering 1988;2(3):193-9.
1988: Dock-Bregeon A C; Chevrier B; Podjarny A; Moras D; deBear J S; Gough G R; Gilham P T; Johnson J E
High resolution structure of the RNA duplex [U(U-A)6A]2.
Nature 1988;335(6188):375-8.
1988: Ruff M; Cavarelli J; Mikol V; Lorber B; Mitschler A; Giege R; Thierry J C; Moras D
A high resolution diffracting crystal form of the complex between yeast tRNAAsp and aspartyl-tRNA synthetase.
Journal of molecular biology 1988;201(1):235-6.
1988: Westhof E; Dumas P; Moras D
Restrained refinement of two crystalline forms of yeast aspartic acid and phenylalanine transfer RNA crystals.
Acta crystallographica. Section A, Foundations of crystallography 1988;44 ( Pt 2)():112-23.
1987: Rondeau J M; Samama J P; Samama B; Barth P; Moras D; Biellmann J F
Crystallization and preliminary X-ray study of pig lens aldose reductase.
Journal of molecular biology 1987;195(4):945-8.
1987: Rees B; Samama J P; Thierry J C; Gilibert M; Fischer J; Schweitz H; Lazdunski M; Moras D
Crystal structure of a snake venom cardiotoxin.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(10):3132-6.
1987: Romby P; Moras D; Dumas P; Ebel J P; Giegé R
Comparison of the tertiary structure of yeast tRNA(Asp) and tRNA(Phe) in solution. Chemical modification study of the bases.
Journal of molecular biology 1987;195(1):193-204.
1987: Dumas P; Moras D; Florentz C; Giegé R; Verlaan P; Van Belkum A; Pleij C W
3-D graphics modelling of the tRNA-like 3'-end of turnip yellow mosaic virus RNA: structural and functional implications.
Journal of biomolecular structure & dynamics 1987;4(5):707-28.
1987: Dock-Bregeon A C; Moras D
Conformational changes and dynamics of tRNAs: evidence from hydrolysis patterns.
Cold Spring Harbor symposia on quantitative biology 1987;52():113-21.
1987: Rondeau J M; Samama J P; Barth P; Moras D; Biellmann J F
Pig lens aldose reductase: purification and preliminary X-ray diffraction study. Oligomerization of the enzyme.
Progress in clinical and biological research 1987;232():377-82.
1986: Romby P; Westhof E; Moras D; Giegé R; Houssier C; Grosjean H
Studies on anticodon-anticodon interactions: hemi-protonation of cytosines induces self-pairing through the GCC anticodon of E. coli tRNA-Gly.
Journal of biomolecular structure & dynamics 1986;4(2):193-203.
1985: Moras D; Dock A C; Dumas P; Westhof E; Romby P; Ebel J P; Giegé R
The structure of yeast tRNA(Asp). A model for tRNA interacting with messenger RNA.
Journal of biomolecular structure & dynamics 1985;3(3):479-93.
1984: Moras D; Thierry J C; Cavarelli J; Piémont Y
Preliminary crystallographic data for exfoliative toxin B from Staphylococcus aureus.
Journal of molecular biology 1984;175(1):89-91.
1984: Dock A C; Lorber B; Moras D; Pixa G; Thierry J C; Giégé R
Crystallization of transfer ribonucleic acids.
Biochimie 1984;66(3):179-201.
1984: Huong P V; Audry E; Giege R; Moras D; Thierry J C; Comarmond M B
Conformational change in yeast tRNAAsp.
Biopolymers 1984;23(1):71-81.
1983: Westhof E; Dumas P; Moras D
Loop stereochemistry and dynamics in transfer RNA.
Journal of biomolecular structure & dynamics 1983;1(2):337-55.
1983: Moras D; Lorber B; Romby P; Ebel J P; Giegé R; Lewit-Bentley A; Roth M
Yeast tRNAAsp-aspartyl-tRNA synthetase: the crystalline complex.
Journal of biomolecular structure & dynamics 1983;1(1):209-23.
1983: Lorber B; Giegé R; Ebel J P; Berthet C; Thierry J C; Moras D
Crystallization of a tRNA . aminoacyl-tRNA synthetase complex. Characterization and first crystallographic data.
The Journal of biological chemistry 1983;258(13):8429-35.
1982: Giegé R; Lorber B; Ebel J P; Moras D; Thierry J C; Jacrot B; Zaccai G
Formation of a catalytically active complex between tRNAAsp and aspartyl-tRNA synthetase from yeast in high concentrations of ammonium sulphate.
Biochimie 1982;64(5):357-62.
1980: Moras D; Comarmond M B; Fischer J; Weiss R; Thierry J C; Ebel J P; Giegé R
Crystal structure of yeast tRNAAsp.
Nature 1980;288(5792):669-74.
1980: Giegé R; Lorber B; Ebel J P; Moras D; Thierry J C
[Crystallization of the complex formed between yeast aspartyl tRNA and its specific aminoacyl tRNA synthetase]
Comptes rendus des séances de l'Académie des sciences. Série D, Sciences naturelles 1980;291(4):393-6.
1980: Dietrich A; Giege R; Comarmond M B; Thierry J C; Moras D
Crystallographic studies on the aspartyl-tRNA synthetase-tRNAAsp system from yeast. The crystalline aminoacyl-tRNA synthetase.
Journal of molecular biology 1980;138(1):129-35.

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