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Alvaro Mordente

Research Profile

Chemicals & Drugs

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Oxidation-Reduction

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Lipid Peroxidation

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Publications

TOP 3
Davide Pirolli; Silvana Ficarra; Bruno Giardina; Alvaro Mordente; M Cristina De Rosa
Understanding the binding of daunorubicin and doxorubicin to NADPH-dependent cytosolic reductases by computational methods.
Alvaro Mordente; Andrea Silvestrini; Giuseppe Ettore Martorana; Elisabetta Meucci; Bruno Giardina
Anthracyclines and mitochondria.
Jacopo Gervasoni; Alvaro Mordente; Fabio Bonelli; Riccardo Calvani; Bruno Zappacosta; Cecilia Zuppi; Silvia Persichilli
Determination of asymmetric dimethyl arginine in human serum by liquid chromatography-tandem mass spectrometry: clinical application in hypertensive subjects.

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All Publications

2012: Davide Pirolli; Silvana Ficarra; Bruno Giardina; Alvaro Mordente; M Cristina De Rosa
Understanding the binding of daunorubicin and doxorubicin to NADPH-dependent cytosolic reductases by computational methods.
European journal of medicinal chemistry 2012;56():145-54.
2012: Alvaro Mordente; Andrea Silvestrini; Giuseppe Ettore Martorana; Elisabetta Meucci; Bruno Giardina
Anthracyclines and mitochondria.
Advances in experimental medicine and biology 2012;942():385-419.
2011: Jacopo Gervasoni; Alvaro Mordente; Fabio Bonelli; Riccardo Calvani; Bruno Zappacosta; Cecilia Zuppi; Silvia Persichilli
Determination of asymmetric dimethyl arginine in human serum by liquid chromatography-tandem mass spectrometry: clinical application in hypertensive subjects.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2011;49(12):2109-15.
2011: Alvaro Mordente; B Guantario; Elisabetta Meucci; A Silvestrini; E Lombardi; Giuseppe Ettore Martorana; Bruno Giardina; V Böhm
Lycopene and cardiovascular diseases: an update.
Current medicinal chemistry 2011;18(8):1146-63.
2009: Anna Rita Fetoni; Massimiliano Garzaro; Massimo Ralli; Vincenzo Landolfo; Matteo Sensini; Giancarlo Pecorari; Alvaro Mordente; Gaetano Paludetti; Carlo Giordano
The monitoring role of otoacoustic emissions and oxidative stress markers in the protective effects of antioxidant administration in noise-exposed subjects: a pilot study.
Medical science monitor : international medical journal of experimental and clinical research 2009;15(11):PR1-8.
2009: Alvaro Mordente; Elisabetta Meucci; Andrea Silvestrini; Giuseppe Ettore Martorana; Bruno Giardina
New developments in anthracycline-induced cardiotoxicity.
Current medicinal chemistry 2009;16(13):1656-72.
2006: Andrea Silvestrini; Elisabetta Meucci; Alberto Vitali; Bruno Giardina; Alvaro Mordente
Chalcone inhibition of anthracycline secondary alcohol metabolite formation in rabbit and human heart cytosol.
Chemical research in toxicology 2006;19(11):1518-24.
2006: Bruno Sergi; Anna Rita Fetoni; Gaetano Paludetti; Aldo Ferraresi; Pierluigi Navarra; Alvaro Mordente; Diana Troiani
Protective properties of idebenone in noise-induced hearing loss in the guinea pig.
Neuroreport 2006;17(9):857-61.
2006: Emanuela Salvatorelli; Simone Guarnieri; Pierantonio Menna; Giovanni Liberi; Antonio M Calafiore; Maria A Mariggiò; Alvaro Mordente; Luca Gianni; Giorgio Minotti
Defective one- or two-electron reduction of the anticancer anthracycline epirubicin in human heart. Relative importance of vesicular sequestration and impaired efficiency of electron addition.
The Journal of biological chemistry 2006;281(16):10990-1001.
2004: Antonio Mancini; Elisabetta Meucci; Domenico Milardi; Elena Giacchi; Antonio Bianchi; Angelo Lauria Pantano; Alvaro Mordente; Giuseppe Ettore Martorana; Laura De Marinis
Seminal antioxidant capacity in pre- and postoperative varicocele.
Journal of andrology 2004;25(1):44-9.
2003: Cesare Mancuso; Alessia Bonsignore; Enrico Di Stasio; Alvaro Mordente; Roberto Motterlini
Bilirubin and S-nitrosothiols interaction: evidence for a possible role of bilirubin as a scavenger of nitric oxide.
Biochemical pharmacology 2003;66(12):2355-63.
2003: Francesco Misiti; Bruno Giardina; Alvaro Mordente; M E Clementi
The secondary alcohol and aglycone metabolites of doxorubicin alter metabolism of human erythrocytes.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 2003;36(12):1643-51.
2003: Alvaro Mordente; Giorgio Minotti; Giuseppe Ettore Martorana; Andrea Silvestrini; Bruno Giardina; Elisabetta Meucci
Anthracycline secondary alcohol metabolite formation in human or rabbit heart: biochemical aspects and pharmacologic implications.
Biochemical pharmacology 2003;66(6):989-98.
2003: Elisabetta Meucci; Domenico Milardi; Alvaro Mordente; Giuseppe Ettore Martorana; Elena Giacchi; Laura De Marinis; Antonio Mancini
Total antioxidant capacity in patients with varicoceles.
Fertility and sterility 2003;79 Suppl 3():1577-83.
2003: Maria Elisabetta Clementi; Bruno Giardina; Enrico Di Stasio; Alvaro Mordente; Francesco Misiti
Doxorubicin-derived metabolites induce release of cytochrome C and inhibition of respiration on cardiac isolated mitochondria.
Anticancer research 2003;23(3B):2445-50.
2002: Maria Emilia De Leo; Adelaide Tranghese; Massimo Passantino; Alvaro Mordente; Marco M Lizzio; Tommaso Galeotti; Angelo Zoli
Manganese superoxide dismutase, glutathione peroxidase, and total radical trapping antioxidant capacity in active rheumatoid arthritis.
The Journal of rheumatology 2002;29(10):2245-6.
2002: Bruno Zappacosta; Silvia Persichilli; Alvaro Mordente; Angelo Minucci; Daniele Lazzaro; Elisabetta Meucci; Bruno Giardina
Inhibition of salivary enzymes by cigarette smoke and the protective role of glutathione.
Human & experimental toxicology 2002;21(1):7-11.
2001: Bruno Zappacosta; Alvaro Mordente; Silvia Persichilli; Angelo Minucci; P Carlino; Giuseppe Ettore Martorana; Bruno Giardina; Pasquale De Sole
Is homocysteine a pro-oxidant?
Free radical research 2001;35(5):499-505.
2001: Alvaro Mordente; Elisabetta Meucci; Giuseppe Ettore Martorana; Bruno Giardina; Giorgio Minotti
Human heart cytosolic reductases and anthracycline cardiotoxicity.
IUBMB life 2001;52(1-2):83-8.
2000: Bruno Zappacosta; Alvaro Mordente; Silvia Persichilli; Bruno Giardina; Pasquale De Sole
Effect of homocysteine on polymorphonuclear leukocyte activity and luminol-dependent chemiluminescence.
Luminescence : the journal of biological and chemical luminescence 2000;15(4):257-60.
2000: S Licata; A Saponiero; Alvaro Mordente; Giorgio Minotti
Doxorubicin metabolism and toxicity in human myocardium: role of cytoplasmic deglycosidation and carbonyl reduction.
Chemical research in toxicology 2000;13(5):414-20.
2000: Giovanni Vento; M C Mele; Alvaro Mordente; Costantino Romagnoli; Piero Giuseppe Matassa; Enrico Zecca; Bruno Zappacosta; Silvia Persichilli
High total antioxidant activity and uric acid in tracheobronchial aspirate fluid of preterm infants during oxidative stress: an adaptive response to hyperoxia?
Acta paediatrica (Oslo, Norway : 1992) 2000;89(3):336-42.
2000: Stefano Rigattieri; Antonino Buffon; V Ramazzotti; Alvaro Mordente; Filippo Crea; Attilio Maseri; B Giardina; S A Santini
Oxidative stress in ischemia-reperfusion injury: assessment by three independent biochemical markers.
Italian heart journal : official journal of the Italian Federation of Cardiology 2000;1(1):68-72.
1999: Bruno Zappacosta; Silvia Persichilli; Pasquale De Sole; Alvaro Mordente; B Giardina
Effect of smoking one cigarette on antioxidant metabolites in the saliva of healthy smokers.
Archives of oral biology 1999;44(6):485-8.
1998: Maria Emilia De Leo; Silvia Borrello; M Passantino; B Palazzotti; Alvaro Mordente; antonio daniele; Valeria Filippini; Tommaso Galeotti; Carlo Masullo
Oxidative stress and overexpression of manganese superoxide dismutase in patients with Alzheimer's disease.
Neuroscience letters 1998;250(3):173-6.
1998: Giorgio Minotti; Stefania Recalcati; Alvaro Mordente; Giovanni Liberi; Antonio M Calafiore; Cesare Mancuso; P Preziosi; Gaetano Cairo
The secondary alcohol metabolite of doxorubicin irreversibly inactivates aconitase/iron regulatory protein-1 in cytosolic fractions from human myocardium.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(7):541-52.
1998: Alvaro Mordente; Giuseppe Ettore Martorana; Giorgio Minotti; Bruno Giardina
Antioxidant properties of 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone (idebenone).
Chemical research in toxicology 1998;11(1):54-63.
1997: Stefano Angelo Santini; G Marra; Bruno Giardina; Patrizia Cotroneo; Alvaro Mordente; Giuseppe Ettore Martorana; Andrea Manto; Giovanni Ghirlanda
Defective plasma antioxidant defenses and enhanced susceptibility to lipid peroxidation in uncomplicated IDDM.
Diabetes 1997;46(11):1853-8.
1996: Giorgio Minotti; Cesare Mancuso; A Frustaci; Alvaro Mordente; S A Santini; A M Calafiore; G Liberi; Nicola Gentiloni
Paradoxical inhibition of cardiac lipid peroxidation in cancer patients treated with doxorubicin. Pharmacologic and molecular reappraisal of anthracycline cardiotoxicity.
The Journal of clinical investigation 1996;98(3):650-61.
1996: S A Santini; Patrizia Cotroneo; G Marra; Andrea Manto; Bruno Giardina; Alvaro Mordente; A V Greco; Giuseppe Ettore Martorana; P Magnani; Giovanni Ghirlanda
NA+/K+ ATPase impairment and experimental glycation: the role of glucose autoxidation.
Free radical research 1996;24(5):381-9.
1995: F Andreasi Bassi; G Arcovito; M De Spirito; Alvaro Mordente; G E Martorana
Self-similarity properties of alpha-crystallin supramolecular aggregates.
Biophysical journal 1995;69(6):2720-7.
1995: Giorgio Minotti; A F Cavaliere; Alvaro Mordente; M Rossi; R Schiavello; R Zamparelli; G Possati
Secondary alcohol metabolites mediate iron delocalization in cytosolic fractions of myocardial biopsies exposed to anticancer anthracyclines. Novel linkage between anthracycline metabolism and iron-induced cardiotoxicity.
The Journal of clinical investigation 1995;95(4):1595-605.
1994: Alvaro Mordente; S A Santini; A G Miggiano; Giuseppe Ettore Martorana; T Petiti; Giorgio Minotti; Bruno Giardina
The interaction of short chain coenzyme Q analogs with different redox states of myoglobin.
The Journal of biological chemistry 1994;269(44):27394-400.
1994: Gian Paolo Littarru; Maurizio Battino; Marco Tomasetti; Alvaro Mordente; S Santini; A Oradei; Andrea Manto; giovanni ghirlanda
Metabolic implications of coenzyme Q10 in red blood cells and plasma lipoproteins.
Molecular aspects of medicine 1994;15 Suppl():s67-72.
1994: Alvaro Mordente; Giuseppe Ettore Martorana; G A Miggiano; T Petitti; Bruno Giardina; Gian Paolo Littarru; S A Santini
Free radical production by activated haem proteins: protective effect of coenzyme Q.
Molecular aspects of medicine 1994;15 Suppl():s109-15.
1993: Alvaro Mordente; Giuseppe Ettore Martorana; S A Santini; G A Miggiano; T Petitti; Bruno Giardina; Maurizio Battino; Gian Paolo Littarru
Antioxidant effect of coenzyme Q on hydrogen peroxide-activated myoglobin.
The Clinical investigator 1993;71(8 Suppl):S92-6.
1992: S A Santini; Alvaro Mordente; E Meucci; G A Miggiano; Giuseppe Ettore Martorana
Conformational stability of bovine alpha-crystallin. Evidence for a destabilizing effect of ascorbate.
The Biochemical journal 1992;287 ( Pt 1)():107-12.
1992: Alvaro Mordente; Giuseppe Ettore Martorana; E Meucci; S A Santini; Gian Paolo Littarru
Enzyme inactivation by metal-catalyzed oxidation of coenzyme Q1.
Biochimica et biophysica acta 1992;1100(3):235-41.
1991: E Meucci; Alvaro Mordente; Giuseppe Ettore Martorana
Metal-catalyzed oxidation of human serum albumin: conformational and functional changes. Implications in protein aging.
The Journal of biological chemistry 1991;266(8):4692-9.
1990: Alvaro Mordente; E Meucci; G A Miggiano; Giuseppe Ettore Martorana
Prooxidant action of desferrioxamine: enhancement of alkaline phosphatase inactivation by interaction with ascorbate system.
Archives of biochemistry and biophysics 1990;277(2):234-40.
1989: G A Miggiano; Alvaro Mordente; Giuseppe Ettore Martorana; A Castelli
Time-resolved fractionation of bone and liver alkaline phosphatase activities with a 'peeling-off' method.
Enzyme 1989;41(2):61-7.
1988: G A Miggiano; Giuseppe Ettore Martorana; Alvaro Mordente; L Di Bonifacio; A Castelli
(Na+-K+)-ATPase interaction with L-ascorbic acid. Effect on p-nitrohenylphosphatase partial reaction.
The Italian journal of biochemistry 1988;37(5):284-92.
1988: Alvaro Mordente; Giuseppe Ettore Martorana; G A Miggiano; E Meucci; S A Santini; A Castelli
Mixed function oxidation and enzymes: kinetic and structural properties of an oxidatively modified alkaline phosphatase.
Archives of biochemistry and biophysics 1988;264(2):502-9.
1987: G A Miggiano; Alvaro Mordente; M G Pischiutta; Giuseppe Ettore Martorana; A Castelli
Early conformational changes and activity modulation induced by guanidinium chloride on intestinal alkaline phosphatase.
The Biochemical journal 1987;248(2):551-6.
1987: Alvaro Mordente; G A Miggiano; Giuseppe Ettore Martorana; E Meucci; S A Santini; A Castelli
Alkaline phosphatase inactivation by mixed function oxidation systems.
Archives of biochemistry and biophysics 1987;258(1):176-85.
1987: G A Miggiano; Alvaro Mordente; Giuseppe Ettore Martorana; M G Pischiutta; A Castelli
Comparison of kinetic and optical changes during guanidine denaturation of intestinal alkaline phosphatase.
The Italian journal of biochemistry 1987;36(4):233-42.
1987: E Meucci; Giuseppe Ettore Martorana; A Ursitti; G A Miggiano; Alvaro Mordente; A Castelli
Vitamin C-bovine serum albumin binding behaviour.
The Italian journal of biochemistry 1987;36(2):75-81.
1986: Giuseppe Ettore Martorana; E Meucci; A Ursitti; G A Miggiano; Alvaro Mordente; A Castelli
The relationship between the optical properties and the kinetic behaviour of ascorbate-inhibited alkaline phosphatase.
The Biochemical journal 1986;240(3):667-71.
1986: G A Miggiano; Alvaro Mordente; M G Pischiutta; Giuseppe Ettore Martorana; A Castelli
The kinetics of concurrent instantaneous and time dependent inhibition of alkaline phosphatase by urea and related compounds.
The Italian journal of biochemistry 1986;35(1):33-41.
1985: G A Miggiano; Alvaro Mordente; Giuseppe Ettore Martorana; A Castelli
Modification of arginine residues in calf intestinal alkaline phosphatase.
The Italian journal of biochemistry 1985;34(5):364-72.
1985: G A Miggiano; M Pileri; Alvaro Mordente; G E Martorana; A Castelli
Placental alkaline phosphatase determination by inhibition with ethylendiaminetetracetic acid.
Clinica chimica acta; international journal of clinical chemistry 1985;145(3):331-6.
1985: G A Miggiano; Giuseppe Ettore Martorana; Alvaro Mordente; A Castelli
Biochemical properties of alkaline phosphatase from endometrial cancer cells.
Enzyme 1985;34(3):113-21.
1984: G A Miggiano; Alvaro Mordente; Giuseppe Ettore Martorana; E Meucci; A Castelli
Characterization of alkaline phosphatase inactivation by ascorbic acid.
Biochimica et biophysica acta 1984;789(3):343-6.
1984: Giuseppe Ettore Martorana; E Meucci; G A Miggiano; Alvaro Mordente; A Ursitti; A Castelli
Modifications induced by ascorbic acid on alkaline phosphatase fluorescence.
The Italian journal of biochemistry 1984;33(5):311-8.
1984: G A Miggiano; Alvaro Mordente; M Pileri; Giuseppe Ettore Martorana; E Meucci; A Castelli
Studies on the selective chemical inhibition by urea of alkaline phosphatase isoenzymes in the reaction course.
Enzyme 1984;32(3):162-9.
1983: Giuseppe Ettore Martorana; E Meucci; G A Miggiano; Alvaro Mordente; A Castelli
Interaction between alkaline phosphatase and ascorbic acid by fluorescence and absorption studies.
The Italian journal of biochemistry 1983;32(4):231-8.
1983: G A Miggiano; Alvaro Mordente; Giuseppe Ettore Martorana; E Meucci; A Castelli
A kinetic approach to the evaluation of alkaline phosphatase inactivation by urea.
The Italian journal of biochemistry 1983;32(4):223-30.
1983: G A Miggiano; Alvaro Mordente; Giuseppe Ettore Martorana; E Meucci; A Castelli
Modulation of alkaline phosphatase in different organs by ascorbic acid and related compounds.
Acta vitaminologica et enzymologica 1983;5(4):219-24.
1983: G A Miggiano; Alvaro Mordente; Giuseppe Ettore Martorana; E Meucci; A Castelli
Ascorbic acid and alkaline phosphatase activity.
Enzyme 1983;30(2):145-8.
1983: G A Miggiano; Alvaro Mordente; Giuseppe Ettore Martorana; E Meucci; A Castelli
In vitro effect of ascorbic acid on bovine kidney alkaline phosphatase activity.
Acta vitaminologica et enzymologica 1983;5(3):153-8.