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Françoise Morel

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Minh Vu Chuong Nguyen; Francis Rousset; Lena Serrander; Candice Trocmé; Leilei Zhang; Florence Hazane-Puch; Karl-Heinz Krause; Bernard Lardy; Françoise Morel
Quinone compounds regulate the level of ROS production by the NADPH oxidase Nox4.
Minh Vu Chuong Nguyen; Leilei Zhang; Nicolas Mouz; Bernard Lardy; Jean-Luc Lenormand; Stanislas Lhomme; Françoise Morel
Recombinant Nox4 cytosolic domain produced by a cell or cell-free base systems exhibits constitutive diaphorase activity.
Sylvie Berthier; Marc-André Hograindleur; Minh Vu Chuong Nguyen; Marie-Hélène Paclet; B Polack; Athan Baillet; Françoise Morel
Molecular interface of S100A8 with cytochrome b558 and NADPH oxidase activation.

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All Publications

2013: Minh Vu Chuong Nguyen; Francis Rousset; Lena Serrander; Candice Trocmé; Leilei Zhang; Florence Hazane-Puch; Karl-Heinz Krause; Bernard Lardy; Françoise Morel
Quinone compounds regulate the level of ROS production by the NADPH oxidase Nox4.
Biochemical pharmacology 2013;85(11):1644-54.
2012: Minh Vu Chuong Nguyen; Leilei Zhang; Nicolas Mouz; Bernard Lardy; Jean-Luc Lenormand; Stanislas Lhomme; Françoise Morel
Recombinant Nox4 cytosolic domain produced by a cell or cell-free base systems exhibits constitutive diaphorase activity.
Biochemical and biophysical research communications 2012;419(3):453-8.
2012: Sylvie Berthier; Marc-André Hograindleur; Minh Vu Chuong Nguyen; Marie-Hélène Paclet; B Polack; Athan Baillet; Françoise Morel
Molecular interface of S100A8 with cytochrome b558 and NADPH oxidase activation.
PloS one 2012;7(7):e40277.
2011: Athan Baillet; Sylvie Berthier; Alexei Grichine; Françoise Morel; Rang Xu; Marie-Hélène Paclet
Coupling of 6-phosphogluconate dehydrogenase with NADPH oxidase in neutrophils: Nox2 activity regulation by NADPH availability.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011;25(7):2333-43.
2011: Leilei Zhang; Minh Vu Chuong Nguyen; Bernard Lardy; Algirdas J Jesaitis; Alexei Grichine; Francis Rousset; Monique Talbot; Marie-Hélène Paclet; Guanxiang Qian; Françoise Morel
New insight into the Nox4 subcellular localization in HEK293 cells: first monoclonal antibodies against Nox4.
Biochimie 2011;93(3):457-68.
2009: Yannick Campion; Algirdas J Jesaitis; Minh Vu Chuong Nguyen; Alexei Grichine; Yvan Herenger; Athan Baillet; Sylvie Berthier; Françoise Morel; Marie-Hélène Paclet
New p22-phox monoclonal antibodies: identification of a conformational probe for cytochrome b 558.
Journal of innate immunity 2009;1(6):556-69.
2007: Yann Verchier; Bernard Lardy; Minh Vu Chuong Nguyen; Françoise Morel; Stéphane Arbault; Christian Amatore
Concerted activities of nitric oxide synthases and NADPH oxidases in PLB-985 cells.
Biochemical and biophysical research communications 2007;361(2):493-8.
2007: Yannick Campion; Marie-Hélène Paclet; Algirdas J Jesaitis; Bruno Marques; Alexei Grichine; Sylvie Berthier; Jean-Luc Lenormand; Bernard Lardy; Marie-José Stasia; Françoise Morel
New insights into the membrane topology of the phagocyte NADPH oxidase: characterization of an anti-gp91-phox conformational monoclonal antibody.
Biochimie 2007;89(9):1145-58.
2007: Marie-Hélène Paclet; Sylvie Berthier; Lauriane Kuhn; Jérôme Garin; Françoise Morel
Regulation of phagocyte NADPH oxidase activity: identification of two cytochrome b558 activation states.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(4):1244-55.
2007: Bruno Marques; Lavinia Liguori; Marie-Hélène Paclet; Ana Villegas-Mendéz; Romy Rothe; Françoise Morel; Jean-Luc Lenormand
Liposome-mediated cellular delivery of active gp91(phox).
PloS one 2007;2(9):e856.
2007: Xing Jun Li; Franck Fieschi; Marie-Hélène Paclet; Didier Grunwald; Yannick Campion; philippe gaudin; Françoise Morel; Marie-José Stasia
Leu505 of Nox2 is crucial for optimal p67phox-dependent activation of the flavocytochrome b558 during phagocytic NADPH oxidase assembly.
Journal of leukocyte biology 2007;81(1):238-49.
2006: Laurent Grange; Minh Vu Chuong Nguyen; Bernard Lardy; Madiha Derouazi; Yannick Campion; Candice Trocme; Marie-Hélène Paclet; philippe gaudin; Françoise Morel
NAD(P)H oxidase activity of Nox4 in chondrocytes is both inducible and involved in collagenase expression.
Antioxidants & redox signaling 2006;8(9-10):1485-96.
2005: Bernard Lardy; Mireille Bof; Laurence Aubry; Marie-Hélène Paclet; Françoise Morel; Michel Satre; Gérard Klein
NADPH oxidase homologs are required for normal cell differentiation and morphogenesis in Dictyostelium discoideum.
Biochimica et biophysica acta 2005;1744(2):199-212.
2005: Xing Jun Li; Didier Grunwald; Jacques Mathieu; Françoise Morel; Marie-José Stasia
Crucial role of two potential cytosolic regions of Nox2, 191TSSTKTIRRS200 and 484DESQANHFAVHHDEEKD500, on NADPH oxidase activation.
The Journal of biological chemistry 2005;280(15):14962-73.
2005: Marie-José Stasia; Pierre Bordigoni; Daniel Floret; Jean Paul Brion; Cécile Bost-Bru; Gérard Michel; Pierre Gatel; Denis Durant-Vital; Marie Antoinette Voelckel; Xing Jun Li; Michèle Guillot; Elisabeth Maquet; Cécile Martel; Françoise Morel
Characterization of six novel mutations in the CYBB gene leading to different sub-types of X-linked chronic granulomatous disease.
Human genetics 2005;116(1-2):72-82.
2004: Clara Bionda; Xing Jun Li; Robin van Bruggen; Michel Eppink; Dirk Roos; Françoise Morel; Marie-José Stasia
Functional analysis of two-amino acid substitutions in gp91 phox in a patient with X-linked flavocytochrome b558-positive chronic granulomatous disease by means of transgenic PLB-985 cells.
Human genetics 2004;115(5):418-27.
2004: Marie-Hélène Paclet; Lydia M Henderson; Yannick Campion; Françoise Morel; Marie-Claire Dagher
Localization of Nox2 N-terminus using polyclonal antipeptide antibodies.
The Biochemical journal 2004;382(Pt 3):981-6.
2003: Marie-José Stasia; Jean-Paul Brion; Jean Boutonnat; Françoise Morel
Severe clinical forms of cytochrome b-negative chronic granulomatous disease (X91-) in 3 brothers with a point mutation in the promoter region of CYBB.
The Journal of infectious diseases 2003;188(10):1593-604.
2003: Sylvie Berthier; Marie-Hélène Paclet; Sandra Lerouge; Florence Roux; Sabrina Vergnaud; Anthony W Coleman; Françoise Morel
Changing the conformation state of cytochrome b558 initiates NADPH oxidase activation: MRP8/MRP14 regulation.
The Journal of biological chemistry 2003;278(28):25499-508.
2003: Pham My-Chan Dang; Françoise Morel; Marie-Anne Gougerot-Pocidalo; Jamel El Benna
Phosphorylation of the NADPH oxidase component p67(PHOX) by ERK2 and P38MAPK: selectivity of phosphorylated sites and existence of an intramolecular regulatory domain in the tetratricopeptide-rich region.
Biochemistry 2003;42(15):4520-6.
2002: Frédérique Monier; Serge Mollier; Michèle Guillot; Jean-Jacques Rambeaud; Françoise Morel; Philippe Zaoui
Urinary release of 72 and 92 kDa gelatinases, TIMPs, N-GAL and conventional prognostic factors in urothelial carcinomas.
European urology 2002;42(4):356-63.
2002: Patryk Moskwa; Marie-Claire Dagher; Marie-Hélène Paclet; Françoise Morel; Erzsébet Ligeti
Participation of Rac GTPase activating proteins in the deactivation of the phagocytic NADPH oxidase.
Biochemistry 2002;41(34):10710-6.
2002: Candice Trocmé; philippe gaudin; Sylvie Berthier; Françoise Morel
Regulation of TIMP-1 phenotypic expression in Epstein--Barr virus-immortalized B lymphocytes.
Biochimica et biophysica acta 2002;1590(1-3):167-76.
2002: Marie-José Stasia; Pierre Bordigoni; Cécile Martel; Françoise Morel
A novel and unusual case of chronic granulomatous disease in a child with a homozygous 36-bp deletion in the CYBA gene (A22(0)) leading to the activation of a cryptic splice site in intron 4.
Human genetics 2002;110(5):444-50.
2002: Marie-José Stasia; Bernard Lardy; Andrés Maturana; Pascale Rousseau; Cécile Martel; Pierre Bordigoni; Nicolas Demaurex; Françoise Morel
Molecular and functional characterization of a new X-linked chronic granulomatous disease variant (X91+) case with a double missense mutation in the cytosolic gp91phox C-terminal tail.
Biochimica et biophysica acta 2002;1586(3):316-30.
2001: L Grang; philippe gaudin; C Trocme; Xavier Phelip; Françoise Morel; Robert Juvin
Intervertebral disk degeneration and herniation: the role of metalloproteinases and cytokines.
Joint, bone, spine : revue du rhumatisme 2001;68(6):547-53.
2001: Marie-Hélène Paclet; Anthony W Coleman; J Burritt; Françoise Morel
NADPH oxidase of Epstein-Barr-virus immortalized B lymphocytes. Effect of cytochrome b(558) glycosylation.
European journal of biochemistry / FEBS 2001;268(19):5197-208.
2001: Miklós Geiszt; Marie-Claire Dagher; Gergely Z Molnár; A Havasi; J Faure; Marie-Hélène Paclet; Françoise Morel; Erzsébet Ligeti
Characterization of membrane-localized and cytosolic Rac-GTPase-activating proteins in human neutrophil granulocytes: contribution to the regulation of NADPH oxidase.
The Biochemical journal 2001;355(Pt 3):851-8.
2000: philippe gaudin; Candice Trocmé; Sylvie Berthier; S Kieffer; Jean Boutonnat; C Lamy; A Surla; J Garin; Françoise Morel
TIMP-1/MMP-9 imbalance in an EBV-immortalized B lymphocyte cellular model: evidence for TIMP-1 multifunctional properties.
Biochimica et biophysica acta 2000;1499(1-2):19-33.
2000: Benoit Polack; Sabrina Vergnaud; Marie-Hélène Paclet; D Lamotte; Bertrand Toussaint; Françoise Morel
Protein delivery by Pseudomonas type III secretion system: Ex vivo complementation of p67(phox)-deficient chronic granulomatous disease.
Biochemical and biophysical research communications 2000;275(3):854-8.
2000: Frédérique Monier; A Surla; M Guillot; Françoise Morel
Gelatinase isoforms in urine from bladder cancer patients.
Clinica chimica acta; international journal of clinical chemistry 2000;299(1-2):11-23.
2000: Marie-Hélène Paclet; Anthony W Coleman; Sabrina Vergnaud; Françoise Morel
P67-phox-mediated NADPH oxidase assembly: imaging of cytochrome b558 liposomes by atomic force microscopy.
Biochemistry 2000;39(31):9302-10.
2000: Philippe Zaoui; J F Cantin; M Alimardani-Bessette; Frédérique Monier; Serge Halimi; Françoise Morel; Daniel Cordonnier
Role of metalloproteases and inhibitors in the occurrence and progression of diabetic renal lesions.
Diabetes & metabolism 2000;26 Suppl 4():25-9.
2000: Sabrina Vergnaud; Marie-Hélène Paclet; Jamel El Benna; M A Pocidalo; Françoise Morel
Complementation of NADPH oxidase in p67-phox-deficient CGD patients p67-phox/p40-phox interaction.
European journal of biochemistry / FEBS 2000;267(4):1059-67.
1999: Jamel El Benna; Pham My-Chan Dang; Valérie Andrieu; Sabrina Vergnaud; Cédric Dewas; O Cachia; Michèle Fay; Françoise Morel; Sylvie Chollet-Martin; J Hakim; Marie-Anne Gougerot-Pocidalo
P40phox associates with the neutrophil Triton X-100-insoluble cytoskeletal fraction and PMA-activated membrane skeleton: a comparative study with P67phox and P47phox.
Journal of leukocyte biology 1999;66(6):1014-20.
1999: Katalin Szászi; A Korda; J Wölfl; Marie-Hélène Paclet; Françoise Morel; Erzsébet Ligeti
Possible role of RAC-GTPase-activating protein in the termination of superoxide production in phagocytic cells.
Free radical biology & medicine 1999;27(7-8):764-72.
1999: Philippe Zaoui; Eliane Rossini; Nicole Pinel; Daniel Cordonnier; Serge Halimi; Françoise Morel
High fructose-fed rats: a model of glomerulosclerosis involving the renin-angiotensin system and renal gelatinases.
Annals of the New York Academy of Sciences 1999;878():716-9.
1998: philippe gaudin; Candice Trocmé; Frédérique Monier; Philippe Zaoui; Claire Barro; B Polack; A Hadjian; Sylvie Berthier; Françoise Morel
[Focalized matrix proteolysis and inflammation].
Annales de biologie clinique 1998;56(6):661-9.
1998: Claire Barro; Philippe Zaoui; Françoise Morel; Pierre Yves Benhamou
Matrix metalloproteinase expression in rat pancreatic islets.
Pancreas 1998;17(4):378-82.
1998: Candice Trocmé; philippe gaudin; Sylvie Berthier; Claire Barro; Philippe Zaoui; Françoise Morel
Human B lymphocytes synthesize the 92-kDa gelatinase, matrix metalloproteinase-9.
The Journal of biological chemistry 1998;273(32):20677-84.
1998: G Batot; Marie-Hélène Paclet; Jacques Doussière; Sabrina Vergnaud; C Martel; Pierre V Vignais; Françoise Morel
Biochemical and immunochemical properties of B lymphocyte cytochrome b558.
Biochimica et biophysica acta 1998;1406(2):188-202.
1998: Philippe Zaoui; Claire Barro; C Maynard; J L Descotes; J Maurizi-Balzan; Daniel Cordonnier; Françoise Morel
Inter-regulated balance between gelatinases and tissue inhibitor (TIMP-1) in isolated human glomeruli.
Renal failure 1998;20(2):201-9.
1997: J E Benna; Pham My-Chan Dang; Murielle Gaudry; Michèle Fay; Françoise Morel; J Hakim; Marie-Anne Gougerot-Pocidalo
Phosphorylation of the respiratory burst oxidase subunit p67(phox) during human neutrophil activation. Regulation by protein kinase C-dependent and independent pathways.
The Journal of biological chemistry 1997;272(27):17204-8.
1997: philippe gaudin; M Razakaboay; A Surla; Sylvie Berthier; J Fauconnier; Françoise Morel; Xavier Phelip
A study of metalloproteinases in fifty joint fluid specimens.
Revue du rhumatisme (English ed.) 1997;64(6):375-81.
1997: philippe gaudin; Sylvie Berthier; Claire Barro; Philippe Zaoui; Françoise Morel
Proteolytic potential of human neutrophil membranes.
European journal of cell biology 1997;72(4):345-51.
1996: Philippe Zaoui; Claire Barro; Françoise Morel
Differential expression and secretion of gelatinases and tissue inhibitor of metalloproteinase-1 during neutrophil adhesion.
Biochimica et biophysica acta 1996;1290(1):101-12.
1995: G Batot; C Martel; N Capdeville; F Wientjes; Françoise Morel
Characterization of neutrophil NADPH oxidase activity reconstituted in a cell-free assay using specific monoclonal antibodies raised against cytochrome b558.
European journal of biochemistry / FEBS 1995;234(1):208-15.
1994: Françoise Morel; B Dewald; Sylvie Berthier; Philippe Zaoui; A C Dianoux; Pierre V Vignais; M Baggiolini
Further characterization of the gelatinase-containing particles of human neutrophils.
Biochimica et biophysica acta 1994;1201(3):373-80.
1993: Françoise Morel; L Cohen Tanugi Cholley; G Brandolin; A C Dianoux; C Martel; P Champelovier; J M Seigneurin; P Francois; M Bost; Pierre V Vignais
The O2- generating oxidase of B lymphocytes: Epstein-Barr virus-immortalized B lymphocytes as a tool for the identification of defective components of the oxidase in chronic granulomatous disease.
Biochimica et biophysica acta 1993;1182(1):101-9.
1993: Françoise Morel; Sylvie Berthier; M Guillot; Philippe Zaoui; C Massoubre; F Didier; Pierre V Vignais
Human neutrophil gelatinase is a collagenase type IV.
Biochemical and biophysical research communications 1993;191(1):269-74.
1992: Françoise Morel; A Surla; Pierre V Vignais
Purification of human placenta diamine oxidase.
Biochemical and biophysical research communications 1992;187(1):178-86.
1992: Françoise Morel; L C Cholley; A C Dianoux; J C Renversez; Daniel Anthony; C Revol; F Boulay; J Gagnon; Pierre V Vignais
Modulation of human neutrophil function by fibronectin degradation products isolated from cryoglobulins.
Inflammation 1992;16(4):325-41.
1991: L Cohen-Tanugi; Françoise Morel; M C Pilloud-Dagher; J M Seigneurin; P Francois; M Bost; Pierre V Vignais
Activation of O2(-)-generating oxidase in an heterologous cell-free system derived from Epstein-Barr-virus-transformed human B lymphocytes and bovine neutrophils. Application to the study of defects in cytosolic factors in chronic granulomatous disease.
European journal of biochemistry / FEBS 1991;202(2):649-55.
1991: Françoise Morel; F Didier; Sylvie Berthier; B Dewald
[Purification of gelatinase secreted by human polynuclear neutrophils].
Annales de biologie clinique 1991;49(9):468-76.