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Daisy Moreno

Research Profile

Living Beings

Chemicals & Drugs

Physiology

Anatomy

Tumor Cell Line

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Disorders

Acute Myeloid Leukemia

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Phosphorylation

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Publications

TOP 3
Ellen Weisberg; Hwan Geun Choi; Rosemary Barrett; Wenjun Zhou; Jianming Zhang; Arghya Ray; Erik A Nelson; Jingrui Jiang; Daisy Moreno; Richard Stone; Ilene Galinsky; Edward Fox; Sophia Adamia; Andrew L Kung; Nathanael S Gray; James D Griffin
Discovery and characterization of novel mutant FLT3 kinase inhibitors.
Ellen Weisberg; X Deng; H G Choi; R Barrett; Sophia Adamia; A Ray; Daisy Moreno; Andrew L Kung; N Gray; James D Griffin
Beneficial effects of combining a type II ATP competitive inhibitor with an allosteric competitive inhibitor of BCR-ABL for the treatment of imatinib-sensitive and imatinib-resistant CML.
Ellen Weisberg; Hwan Geun Choi; Arghya Ray; Rosemary Barrett; Jianming Zhang; Taebo Sim; Wenjun Zhou; Markus Seeliger; Michael Cameron; Mohammed Azam; Jonathan A Fletcher; Maria Debiec-Rychter; Mark Mayeda; Daisy Moreno; Andrew L Kung; Pasi A Janne; Roya Khosravi-Far; Junia V Melo; Paul W Manley; Sophia Adamia; Catherine Wu; Nathanael Gray; James D Griffin
Discovery of a small-molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRalpha, Kit, and Src kinases: novel type II inhibitor of gatekeeper mutants.

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All Publications

2010: Ellen Weisberg; Hwan Geun Choi; Rosemary Barrett; Wenjun Zhou; Jianming Zhang; Arghya Ray; Erik A Nelson; Jingrui Jiang; Daisy Moreno; Richard Stone; Ilene Galinsky; Edward Fox; Sophia Adamia; Andrew L Kung; Nathanael S Gray; James D Griffin
Discovery and characterization of novel mutant FLT3 kinase inhibitors.
Molecular cancer therapeutics 2010;9(9):2468-77.
2010: Ellen Weisberg; X Deng; H G Choi; R Barrett; Sophia Adamia; A Ray; Daisy Moreno; Andrew L Kung; N Gray; James D Griffin
Beneficial effects of combining a type II ATP competitive inhibitor with an allosteric competitive inhibitor of BCR-ABL for the treatment of imatinib-sensitive and imatinib-resistant CML.
Leukemia 2010;24(7):1375-8.
2010: Ellen Weisberg; Hwan Geun Choi; Arghya Ray; Rosemary Barrett; Jianming Zhang; Taebo Sim; Wenjun Zhou; Markus Seeliger; Michael Cameron; Mohammed Azam; Jonathan A Fletcher; Maria Debiec-Rychter; Mark Mayeda; Daisy Moreno; Andrew L Kung; Pasi A Janne; Roya Khosravi-Far; Junia V Melo; Paul W Manley; Sophia Adamia; Catherine Wu; Nathanael Gray; James D Griffin
Discovery of a small-molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRalpha, Kit, and Src kinases: novel type II inhibitor of gatekeeper mutants.
Blood 2010;115(21):4206-16.
2008: Ellen Weisberg; Johannes Roesel; Guido Bold; Pascal Furet; Jingrui Jiang; Jan Cools; Renee D Wright; Erik Nelson; Rosemary Barrett; Arghya Ray; Daisy Moreno; Elizabeth Hall-Meyers; Richard Stone; Ilene Galinsky; Edward A Fox; Gary Gilliland; John F Daley; Suzan Lazo-Kallanian; Andrew L Kung; James D Griffin
Antileukemic effects of the novel, mutant FLT3 inhibitor NVP-AST487: effects on PKC412-sensitive and -resistant FLT3-expressing cells.
Blood 2008;112(13):5161-70.
2008: Ellen Weisberg; Lolita Banerji; Renee D Wright; Rosemary Barrett; Arghya Ray; Daisy Moreno; Laurence Catley; Jingrui Jiang; Elizabeth Hall-Meyers; Maira Sauveur-Michel; Richard M Stone; Ilene Galinsky; Edward A Fox; Andrew L Kung; James D Griffin
Potentiation of antileukemic therapies by the dual PI3K/PDK-1 inhibitor, BAG956: effects on BCR-ABL- and mutant FLT3-expressing cells.
Blood 2008;111(7):3723-34.
2007: Xavier Leleu; Xiaoying Jia; Judith M Runnels; Hai T Ngo; Anne-Sophie Moreau; Mena Farag; Joel A Spencer; Costas M Pitsillides; Evdoxia Hatjiharissi; Aldo Roccaro; Garrett O'Sullivan; Douglas W McMillin; Daisy Moreno; Tanyel Kiziltepe; Ruben D Carrasco; Steve P Treon; Teru Hideshima; Kenneth C Anderson; Charles P Lin; Irene M Ghobrial
The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia.
Blood 2007;110(13):4417-26.
2007: Ellen Weisberg; Andrew L Kung; Renee D Wright; Daisy Moreno; Laurence Catley; Arghya Ray; Leigh Zawel; Mary Tran; Jan Cools; Gary Gilliland; Constantine S Mitsiades; Douglas W McMillin; Jingrui Jiang; Elizabeth Hall-Meyers; James D Griffin
Potentiation of antileukemic therapies by Smac mimetic, LBW242: effects on mutant FLT3-expressing cells.
Molecular cancer therapeutics 2007;6(7):1951-61.
2007: Ellen Weisberg; Laurence Catley; Renee D Wright; Daisy Moreno; Lolita Banerji; Arghya Ray; Paul W Manley; Jürgen Mestan; Doriano Fabbro; Jingrui Jiang; Elizabeth Hall-Meyers; Linda Callahan; Jamie L DellaGatta; Andrew L Kung; James D Griffin
Beneficial effects of combining nilotinib and imatinib in preclinical models of BCR-ABL+ leukemias.
Blood 2007;109(5):2112-20.
2006: Ellen Weisberg; Renee D Wright; Jingrui Jiang; Arghya Ray; Daisy Moreno; Paul W Manley; Doriano Fabbro; Elizabeth Hall-Meyers; Laurence Catley; klaus podar; Andrew L Kung; James D Griffin
Effects of PKC412, nilotinib, and imatinib against GIST-associated PDGFRA mutants with differential imatinib sensitivity.
Gastroenterology 2006;131(6):1734-42.