Alessandro Moretta

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Marcenaro Emanuela; Cantoni Claudia; Pesce Silvia; Prato Carola; Pende Daniela; Agaugué Sophie; Moretta Lorenzo; Moretta Alessandro
Uptake of CCR7 and acquisition of migratory properties by human KIR+ NK cells interacting with monocyte-derived DC or EBV cell lines: regulation by KIR/HLA-class I interaction.
Brunetta Enrico; Fogli Manuela; Varchetta Stefania; Bozzo Luisa; Hudspeth Kelly L; Marcenaro Emanuela; Moretta Alessandro; Mavilio Domenico
The decreased expression of Siglec-7 represents an early marker of dysfunctional natural killer-cell subsets associated with high levels of HIV-1 viremia.
Balsamo Mirna; Zambello Renato; Teramo Antonella; Pedrazzi Marco; Sparatore Bianca; Scordamaglia Francesca; Pende Daniela; Mingari Maria Cristina; Moretta Lorenzo; Moretta Alessandro; Semenzato Gianpietro; Vitale Massimo
Analysis of NK cell/DC interaction in NK-type lymphoproliferative disease of granular lymphocytes (LDGL): role of DNAM-1 and NKp30.

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All Publications

2009: Marcenaro Emanuela; Cantoni Claudia; Pesce Silvia; Prato Carola; Pende Daniela; Agaugué Sophie; Moretta Lorenzo; Moretta Alessandro
Uptake of CCR7 and acquisition of migratory properties by human KIR+ NK cells interacting with monocyte-derived DC or EBV cell lines: regulation by KIR/HLA-class I interaction.
Blood 2009;114(19):4108-16.
2009: Brunetta Enrico; Fogli Manuela; Varchetta Stefania; Bozzo Luisa; Hudspeth Kelly L; Marcenaro Emanuela; Moretta Alessandro; Mavilio Domenico
The decreased expression of Siglec-7 represents an early marker of dysfunctional natural killer-cell subsets associated with high levels of HIV-1 viremia.
Blood 2009;114(18):3822-30.
2009: Balsamo Mirna; Zambello Renato; Teramo Antonella; Pedrazzi Marco; Sparatore Bianca; Scordamaglia Francesca; Pende Daniela; Mingari Maria Cristina; Moretta Lorenzo; Moretta Alessandro; Semenzato Gianpietro; Vitale Massimo
Analysis of NK cell/DC interaction in NK-type lymphoproliferative disease of granular lymphocytes (LDGL): role of DNAM-1 and NKp30.
Experimental hematology 2009;37(10):1167-75.
2009: Castriconi Roberta; Daga Antonio; Dondero Alessandra; Zona Gianluigi; Poliani Pietro Luigi; Melotti Alice; Griffero Fabrizio; Marubbi Daniela; Spaziante Renato; Bellora Francesca; Moretta Lorenzo; Moretta Alessandro; Corte Giorgio; Bottino Cristina
NK cells recognize and kill human glioblastoma cells with stem cell-like properties.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(6):3530-9.
2009: Costa Paola; Sivori Simona; Bozzano Federica; Martini Isabella; Moretta Alessandro; Moretta Lorenzo; De Maria Andrea
IFN-alpha-mediated increase in cytolytic activity of maturing NK cell upon exposure to HSV-infected myelomonocytes.
European journal of immunology 2009;39(1):147-58.
2009: Marcenaro Emanuela; Della Chiesa Mariella; Pesce Silvia; Agaugué Sophie; Moretta Alessandro
The NK/DC complot.
Advances in experimental medicine and biology 2009;633():7-16.
2008: Moretta L; Locatelli F; Moretta A
Alloreactive natural killer cells in targeting high-risk leukaemias.
Annals of the rheumatic diseases 2008;67 Suppl 3():iii39-43.
2008: Vacca Paola; Cantoni Claudia; Prato Carola; Fulcheri Ezio; Moretta Alessandro; Moretta Lorenzo; Mingari Maria Cristina
Regulatory role of NKp44, NKp46, DNAM-1 and NKG2D receptors in the interaction between NK cells and trophoblast cells. Evidence for divergent functional profiles of decidual versus peripheral NK cells.
International immunology 2008;20(11):1395-405.
2008: Marcenaro Emanuela; Ferranti Bruna; Falco Michela; Moretta Lorenzo; Moretta Alessandro
Human NK cells directly recognize Mycobacterium bovis via TLR2 and acquire the ability to kill monocyte-derived DC.
International immunology 2008;20(9):1155-67.
2008: Agaugué Sophie; Marcenaro Emanuela; Ferranti Bruna; Moretta Lorenzo; Moretta Alessandro
Human natural killer cells exposed to IL-2, IL-12, IL-18, or IL-4 differently modulate priming of naive T cells by monocyte-derived dendritic cells.
Blood 2008;112(5):1776-83.
2008: Moretta Alessandro; Locatelli Franco; Moretta Lorenzo
Human NK cells: from HLA class I-specific killer Ig-like receptors to the therapy of acute leukemias.
Immunological reviews 2008;224():58-69.
2008: Della Chiesa Mariella; Romeo Elisa; Falco Michela; Balsamo Mirna; Augugliaro Raffaella; Moretta Lorenzo; Bottino Cristina; Moretta Alessandro; Vitale Massimo
Evidence that the KIR2DS5 gene codes for a surface receptor triggering natural killer cell function.
European journal of immunology 2008;38(8):2284-9.
2008: Fogli Manuela; Mavilio Domenico; Brunetta Enrico; Varchetta Stefania; Ata Khaled; Roby Gregg; Kovacs Colin; Follmann Dean; Pende Daniela; Ward Jeffrey; Barker Edward; Marcenaro Emanuela; Moretta Alessandro; Fauci Anthony S
Lysis of endogenously infected CD4+ T cell blasts by rIL-2 activated autologous natural killer cells from HIV-infected viremic individuals.
PLoS pathogens 2008;4(7):e1000101.
2008: Moretta A; Marcenaro E; Parolini S; Ferlazzo G; Moretta L
NK cells at the interface between innate and adaptive immunity.
Cell death and differentiation 2008;15(2):226-33.
2007: Sivori Simona; Falco Michela; Carlomagno Simona; Romeo Elisa; Moretta Lorenzo; Moretta Alessandro
Heterogeneity of TLR3 mRNA transcripts and responsiveness to poly (I:C) in human NK cells derived from different donors.
International immunology 2007;19(12):1341-8.
2007: Castriconi Roberta; Dondero Alessandra; Negri Francesca; Bellora Francesca; Nozza Paolo; Carnemolla Barbara; Raso Alessandro; Moretta Lorenzo; Moretta Alessandro; Bottino Cristina
Both CD133+ and CD133- medulloblastoma cell lines express ligands for triggering NK receptors and are susceptible to NK-mediated cytotoxicity.
European journal of immunology 2007;37(11):3190-6.
2007: Castriconi Roberta; Dondero Alessandra; Cilli Michele; Ognio Emanuela; Pezzolo Annalisa; De Giovanni Barbara; Gambini Claudio; Pistoia Vito; Moretta Lorenzo; Moretta Alessandro; Corrias Maria Valeria
Human NK cell infusions prolong survival of metastatic human neuroblastoma-bearing NOD/scid mice.
Cancer immunology, immunotherapy : CII 2007;56(11):1733-42.
2007: Castriconi Roberta; Dondero Alessandra; Cantoni Claudia; Della Chiesa Mariella; Prato Carola; Nanni Marina; Fiorini Maurilia; Notarangelo Lucia; Parolini Silvia; Moretta Lorenzo; Notarangelo Luigi; Moretta Alessandro; Bottino Cristina
Functional characterization of natural killer cells in type I leukocyte adhesion deficiency.
Blood 2007;109(11):4873-81.
2007: Parolini Silvia; Santoro Amerigo; Marcenaro Emanuela; Luini Walter; Massardi Luisa; Facchetti Fabio; Communi David; Parmentier Marc; Majorana Alessandra; Sironi Marina; Tabellini Giovanna; Moretta Alessandro; Sozzani Silvano
The role of chemerin in the colocalization of NK and dendritic cell subsets into inflamed tissues.
Blood 2007;109(9):3625-32.
2007: Romagnani Chiara; Juelke Kerstin; Falco Michela; Morandi Barbara; D'Agostino Antonella; Costa Roberta; Ratto Giovanni; Forte Giuseppe; Carrega Paolo; Lui Gabrielle; Conte Romana; Strowig Till; Moretta Alessandro; Münz Christian; Thiel Andreas; Moretta Lorenzo; Ferlazzo Guido
CD56brightCD16- killer Ig-like receptor- NK cells display longer telomeres and acquire features of CD56dim NK cells upon activation.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(8):4947-55.
2007: Walzer Thierry; Bléry Mathieu; Chaix Julie; Fuseri Nicolas; Chasson Lionel; Robbins Scott H; Jaeger Sébastien; André Pascale; Gauthier Laurent; Daniel Laurent; Chemin Karine; Morel Yannis; Dalod Marc; Imbert Jean; Pierres Michel; Moretta Alessandro; Romagné François; Vivier Eric
Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3384-9.
2007: Zimmer Jacques; Bausinger Huguette; Andrès Emmanuel; Donato Lionel; Hanau Daniel; Hentges François; Moretta Alessandro; de la Salle Henri
Phenotypic studies of natural killer cell subsets in human transporter associated with antigen processing deficiency.
PloS one 2007;2(10):e1033.
2007: Marcenaro Emanuela; Della Chiesa Mariella; Ferranti Bruna; Moretta Alessandro
In the thick of the fray: NK cells in inflamed tissues.
Advances in experimental medicine and biology 2007;598():12-9.
2007: Marcenaro Emanuela; Della Chiesa Mariella; Dondero Alessandra; Ferranti Bruna; Moretta Alessandro
It's only innate immunity but I like it.
Advances in experimental medicine and biology 2007;590():89-101.
2006: Marcenaro E; Dondero A; Moretta A
Multi-directional cross-regulation of NK cell function during innate immune responses.
Transplant immunology 2006;17(1):16-9.
2006: Vacca Paola; Pietra Gabriella; Falco Michela; Romeo Elisa; Bottino Cristina; Bellora Francesca; Prefumo Federico; Fulcheri Ezio; Venturini Pier Luigi; Costa Mauro; Moretta Alessandro; Moretta Lorenzo; Mingari Maria Cristina
Analysis of natural killer cells isolated from human decidua: Evidence that 2B4 (CD244) functions as an inhibitory receptor and blocks NK-cell function.
Blood 2006;108(13):4078-85.
2006: Della Chiesa Mariella; Carlomagno Simona; Frumento Guido; Balsamo Mirna; Cantoni Claudia; Conte Romana; Moretta Lorenzo; Moretta Alessandro; Vitale Massimo
The tryptophan catabolite L-kynurenine inhibits the surface expression of NKp46- and NKG2D-activating receptors and regulates NK-cell function.
Blood 2006;108(13):4118-25.
2006: Della Chiesa Mariella; Romagnani Chiara; Thiel Andreas; Moretta Lorenzo; Moretta Alessandro
Multidirectional interactions are bridging human NK cells with plasmacytoid and monocyte-derived dendritic cells during innate immune responses.
Blood 2006;108(12):3851-8.
2006: Mavilio Domenico; Lombardo Gabriella; Kinter Audrey; Fogli Manuela; La Sala Andrea; Ortolano Saida; Farschi Annahita; Follmann Dean; Gregg Roby; Kovacs Colin; Marcenaro Emanuela; Pende Daniela; Moretta Alessandro; Fauci Anthony S
Characterization of the defective interaction between a subset of natural killer cells and dendritic cells in HIV-1 infection.
The Journal of experimental medicine 2006;203(10):2339-50.
2006: Fontana Stefania; Parolini Silvia; Vermi William; Booth Sarah; Gallo Federico; Donini Marta; Benassi Marzia; Gentili Francesca; Ferrari Daniela; Notarangelo Lucia D; Cavadini Patrizia; Marcenaro Emanuela; Dusi Stefano; Cassatella Marco; Facchetti Fabio; Griffiths Gillian M; Moretta Alessandro; Notarangelo Luigi D; Badolato Raffaele
Innate immunity defects in Hermansky-Pudlak type 2 syndrome.
Blood 2006;107(12):4857-64.
2006: Sivori Simona; Carlomagno Simona; Moretta Lorenzo; Moretta Alessandro
Comparison of different CpG oligodeoxynucleotide classes for their capability to stimulate human NK cells.
European journal of immunology 2006;36(4):961-7.
2006: Pende Daniela; Castriconi Roberta; Romagnani Paola; Spaggiari Grazia Maria; Marcenaro Stefania; Dondero Alessandra; Lazzeri Elena; Lasagni Laura; Martini Stefania; Rivera Paola; Capobianco Andrea; Moretta Lorenzo; Moretta Alessandro; Bottino Cristina
Expression of the DNAM-1 ligands, Nectin-2 (CD112) and poliovirus receptor (CD155), on dendritic cells: relevance for natural killer-dendritic cell interaction.
Blood 2006;107(5):2030-6.
2005: Moretta Alessandro; Marcenaro Emanuela; Sivori Simona; Della Chiesa Mariella; Vitale Massimo; Moretta Lorenzo
Early liaisons between cells of the innate immune system in inflamed peripheral tissues.
Trends in immunology 2005;26(12):668-75.
2005: Marcenaro Emanuela; Ferranti Bruna; Moretta Alessandro
NK-DC interaction: on the usefulness of auto-aggression.
Autoimmunity reviews 2005;4(8):520-5.
2005: Morandi Barbara; Costa Roberta; Falco Michela; Parolini Silvia; De Maria Andrea; Ratto Giovanni; Mingari Maria Cristina; Melioli Giovanni; Moretta Alessandro; Ferlazzo Guido
Distinctive lack of CD48 expression in subsets of human dendritic cells tunes NK cell activation.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(6):3690-7.
2005: Stewart C Andrew; Laugier-Anfossi Fanny; Vély Frédéric; Saulquin Xavier; Riedmuller Jenifer; Tisserant Agnès; Gauthier Laurent; Romagné François; Ferracci Géraldine; Arosa Fernando A; Moretta Alessandro; Sun Peter D; Ugolini Sophie; Vivier Eric
Recognition of peptide-MHC class I complexes by activating killer immunoglobulin-like receptors.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(37):13224-9.
2005: Fauriat Cyril; Moretta Alessandro; Olive Daniel; Costello Régis T
Defective killing of dendritic cells by autologous natural killer cells from acute myeloid leukemia patients.
Blood 2005;106(6):2186-8.
2005: Mavilio Domenico; Benjamin Janet; Kim Diana; Lombardo Gabriella; Daucher Marybeth; Kinter Audrey; Nies-Kraske Elizabeth; Marcenaro Emanuela; Moretta Alessandro; Fauci Anthony S
Identification of NKG2A and NKp80 as specific natural killer cell markers in rhesus and pigtailed monkeys.
Blood 2005;106(5):1718-25.
2005: Moretta Lorenzo; Bottino Cristina; Pende Daniela; Vitale Massimo; Mingari Maria Cristina; Moretta Alessandro
Human natural killer cells: Molecular mechanisms controlling NK cell activation and tumor cell lysis.
Immunology letters 2005;100(1):7-13.
2005: Romagnani Chiara; Della Chiesa Mariella; Kohler Siegfried; Moewes Beate; Radbruch Andreas; Moretta Lorenzo; Moretta Alessandro; Thiel Andreas
Activation of human NK cells by plasmacytoid dendritic cells and its modulation by CD4+ T helper cells and CD4+ CD25hi T regulatory cells.
European journal of immunology 2005;35(8):2452-8.
2005: Vitale Massimo; Della Chiesa Mariella; Carlomagno Simona; Pende Daniela; Aricò Maurizio; Moretta Lorenzo; Moretta Alessandro
NK-dependent DC maturation is mediated by TNFalpha and IFNgamma released upon engagement of the NKp30 triggering receptor.
Blood 2005;106(2):566-71.
2005: Moretta Alessandro
The dialogue between human natural killer cells and dendritic cells.
Current opinion in immunology 2005;17(3):306-11.
2005: Biassoni Roberto; Fogli Manuela; Cantoni Claudia; Costa Paola; Conte Romana; Koopman Gerrit; Cafaro Aurelio; Ensoli Barbara; Moretta Alessandro; Moretta Lorenzo; De Maria Andrea
Molecular and functional characterization of NKG2D, NKp80, and NKG2C triggering NK cell receptors in rhesus and cynomolgus macaques: monitoring of NK cell function during simian HIV infection.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(9):5695-705.
2005: Marcenaro Emanuela; Della Chiesa Mariella; Bellora Francesca; Parolini Silvia; Millo Romano; Moretta Lorenzo; Moretta Alessandro
IL-12 or IL-4 prime human NK cells to mediate functionally divergent interactions with dendritic cells or tumors.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(7):3992-8.
2005: Della Chiesa Mariella; Sivori Simona; Castriconi Roberta; Marcenaro Emanuela; Moretta Alessandro
Pathogen-induced private conversations between natural killer and dendritic cells.
Trends in microbiology 2005;13(3):128-36.
2005: Pende Daniela; Spaggiari Grazia Maria; Marcenaro Stefania; Martini Stefania; Rivera Paola; Capobianco Andrea; Falco Michela; Lanino Edoardo; Pierri Ivana; Zambello Renato; Bacigalupo Andrea; Mingari Maria Cristina; Moretta Alessandro; Moretta Lorenzo
Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112).
Blood 2005;105(5):2066-73.
2005: Mavilio Domenico; Lombardo Gabriella; Benjamin Janet; Kim Diana; Follman Dean; Marcenaro Emanuela; O'Shea M Angeline; Kinter Audrey; Kovacs Colin; Moretta Alessandro; Fauci Anthony S
Characterization of CD56-/CD16+ natural killer (NK) cells: a highly dysfunctional NK subset expanded in HIV-infected viremic individuals.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(8):2886-91.
2005: Pende Daniela; Bottino Cristina; Castriconi Roberta; Cantoni Claudia; Marcenaro Stefania; Rivera Paola; Spaggiari Grazia M; Dondero Alessandra; Carnemolla Barbara; Reymond Nicolas; Mingari Maria Cristina; Lopez Marc; Moretta Lorenzo; Moretta Alessandro
PVR (CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis.
Molecular immunology 2005;42(4):463-9.
2004: Castriconi Roberta; Dondero Alessandra; Corrias Maria Valeria; Lanino Edoardo; Pende Daniela; Moretta Lorenzo; Bottino Cristina; Moretta Alessandro
Natural killer cell-mediated killing of freshly isolated neuroblastoma cells: critical role of DNAX accessory molecule-1-poliovirus receptor interaction.
Cancer research 2004;64(24):9180-4.
2004: Moretta Lorenzo; Bottino Cristina; Pende Daniela; Vitale Massimo; Mingari Maria Cristina; Moretta Alessandro
Different checkpoints in human NK-cell activation.
Trends in immunology 2004;25(12):670-6.
2004: Swaminathan Chittoor P; Wais Neelowfar; Vyas Vinay V; Velikovsky Carlos A; Moretta Alessandro; Moretta Lorenzo; Biassoni Roberto; Mariuzza Roy A; Dimasi Nazzareno
Entropically assisted carbohydrate recognition by a natural killer cell-surface receptor.
Chembiochem : a European journal of chemical biology 2004;5(11):1571-5.
2004: Vitale Massimo; Carlomagno Simona; Falco Michela; Pende Daniela; Romeo Elisa; Rivera Paola; Della Chiesa Mariella; Mavilio Domenico; Moretta Alessandro
Isolation of a novel KIR2DL3-specific mAb: comparative analysis of the surface distribution and function of KIR2DL2, KIR2DL3 and KIR2DS2.
International immunology 2004;16(10):1459-66.
2004: Castriconi Roberta; Dondero Alessandra; Augugliaro Raffaella; Cantoni Claudia; Carnemolla Barbara; Sementa Angela Rita; Negri Francesca; Conte Romana; Corrias Maria Valeria; Moretta Lorenzo; Moretta Alessandro; Bottino Cristina
Identification of 4Ig-B7-H3 as a neuroblastoma-associated molecule that exerts a protective role from an NK cell-mediated lysis.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(34):12640-5.
2004: Fogli Manuela; Costa Paola; Murdaca Giuseppe; Setti Maurizio; Mingari Maria Cristina; Moretta Lorenzo; Moretta Alessandro; De Maria Andrea
Significant NK cell activation associated with decreased cytolytic function in peripheral blood of HIV-1-infected patients.
European journal of immunology 2004;34(8):2313-21.
2004: Moretta Alessandro; Bottino Cristina
Commentary: Regulated equilibrium between opposite signals: a general paradigm for T cell function?
European journal of immunology 2004;34(8):2084-8.
2004: Sivori Simona; Falco Michela; Della Chiesa Mariella; Carlomagno Simona; Vitale Massimo; Moretta Lorenzo; Moretta Alessandro
CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(27):10116-21.
2004: Castriconi Roberta; Della Chiesa Mariella; Moretta Alessandro
Shaping of adaptive immunity by innate interactions.
Comptes rendus biologies 2004;327(6):533-7.
2004: Vitale Massimo; Della Chiesa Mariella; Carlomagno Simona; Romagnani Chiara; Thiel Andreas; Moretta Lorenzo; Moretta Alessandro
The small subset of CD56brightCD16- natural killer cells is selectively responsible for both cell proliferation and interferon-gamma production upon interaction with dendritic cells.
European journal of immunology 2004;34(6):1715-22.
2004: Falco Michela; Marcenaro Emanuela; Romeo Elisa; Bellora Francesca; Marras Daniele; Vély Frédéric; Ferracci Géraldine; Moretta Lorenzo; Moretta Alessandro; Bottino Cristina
Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells.
European journal of immunology 2004;34(6):1663-72.
2004: Reymond Nicolas; Imbert Anne-Marie; Devilard Elisabeth; Fabre Stéphanie; Chabannon Christian; Xerri Luc; Farnarier Catherine; Cantoni Claudia; Bottino Cristina; Moretta Alessandro; Dubreuil Patrice; Lopez Marc
DNAM-1 and PVR regulate monocyte migration through endothelial junctions.
The Journal of experimental medicine 2004;199(10):1331-41.
2004: André Pascale; Castriconi Roberta; Espéli Marion; Anfossi Nicolas; Juarez Tiffany; Hue Sophie; Conway Holli; Romagné François; Dondero Alessandra; Nanni Marina; Caillat-Zucman Sophie; Raulet David H; Bottino Cristina; Vivier Eric; Moretta Alessandro; Paul Pascale
Comparative analysis of human NK cell activation induced by NKG2D and natural cytotoxicity receptors.
European journal of immunology 2004;34(4):961-71.
2004: Dimasi Nazzareno; Moretta Alessandro; Moretta Lorenzo; Biassoni Roberto; Mariuzza Roy A
Structure of the saccharide-binding domain of the human natural killer cell inhibitory receptor p75/AIRM1.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 2):401-3.
2004: Ferlazzo Guido; Thomas Dolca; Lin Shao-Lee; Goodman Kiera; Morandi Barbara; Muller William A; Moretta Alessandro; Münz Christian
The abundant NK cells in human secondary lymphoid tissues require activation to express killer cell Ig-like receptors and become cytolytic.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(3):1455-62.
2003: Ponassi Marco; Cantoni Claudia; Biassoni Roberto; Conte Romana; Spallarossa Andrea; Moretta Alessandro; Moretta Lorenzo; Bolognesi Martino; Bordo Domenico
Expression and crystallographic characterization of the extracellular domain of human natural killer cell triggering receptor NKp46.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 12):2259-61.
2003: Mavilio Domenico; Benjamin Janet; Daucher Marybeth; Lombardo Gabriella; Kottilil Shyam; Planta Marie A; Marcenaro Emanuela; Bottino Cristina; Moretta Lorenzo; Moretta Alessandro; Fauci Anthony S
Natural killer cells in HIV-1 infection: dichotomous effects of viremia on inhibitory and activating receptors and their functional correlates.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):15011-6.
2003: Sivori Simona; Cantoni Claudia; Parolini Silvia; Marcenaro Emanuela; Conte Romana; Moretta Lorenzo; Moretta Alessandro
IL-21 induces both rapid maturation of human CD34+ cell precursors towards NK cells and acquisition of surface killer Ig-like receptors.
European journal of immunology 2003;33(12):3439-47.
2003: Marcenaro Emanuela; Augugliaro Raffaella; Falco Michela; Castriconi Roberta; Parolini Silvia; Sivori Simona; Romeo Elisa; Millo Romano; Moretta Lorenzo; Bottino Cristina; Moretta Alessandro
CD59 is physically and functionally associated with natural cytotoxicity receptors and activates human NK cell-mediated cytotoxicity.
European journal of immunology 2003;33(12):3367-76.
2003: Fauriat Cyril; Marcenaro Emanuela; Sivori Simona; Rey Jérôme; Gastaut Jean-Albert; Moretta Alessandro; Olive Daniel; Costello Régis T
Natural killer cell-triggering receptors in patients with acute leukaemia.
Leukemia & lymphoma 2003;44(10):1683-9.
2003: Pietra Gabriella; Romagnani Chiara; Mazzarino Paola; Falco Michela; Millo Enrico; Moretta Alessandro; Moretta Lorenzo; Mingari Maria Cristina
HLA-E-restricted recognition of cytomegalovirus-derived peptides by human CD8+ cytolytic T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(19):10896-901.
2003: Ponassi Marco; Cantoni Claudia; Biassoni Roberto; Conte Romana; Spallarossa Andrea; Pesce Alessandra; Moretta Alessandro; Moretta Lorenzo; Bolognesi Martino; Bordo Domenico
Structure of the human NK cell triggering receptor NKp46 ectodomain.
Biochemical and biophysical research communications 2003;309(2):317-23.
2003: De Maria Andrea; Fogli Manuela; Costa Paola; Murdaca Giuseppe; Puppo Francesco; Mavilio Domenico; Moretta Alessandro; Moretta Lorenzo
The impaired NK cell cytolytic function in viremic HIV-1 infection is associated with a reduced surface expression of natural cytotoxicity receptors (NKp46, NKp30 and NKp44).
European journal of immunology 2003;33(9):2410-8.
2003: Zambello Renato; Falco Michela; Della Chiesa Mariella; Trentin Livio; Carollo Davide; Castriconi Roberta; Cannas Giovanna; Carlomagno Simona; Cabrelle Anna; Lamy Thierry; Agostini Carlo; Moretta Alessandro; Semenzato Gianpietro; Vitale Massimo
Expression and function of KIR and natural cytotoxicity receptors in NK-type lymphoproliferative diseases of granular lymphocytes.
Blood 2003;102(5):1797-805.
2003: Bottino Cristina; Castriconi Roberta; Pende Daniela; Rivera Paola; Nanni Marina; Carnemolla Barbara; Cantoni Claudia; Grassi Jessica; Marcenaro Stefania; Reymond Nicolas; Vitale Massimo; Moretta Lorenzo; Lopez Marc; Moretta Alessandro
Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule.
The Journal of experimental medicine 2003;198(4):557-67.
2003: Moretta Lorenzo; Mingari Maria Cristina; Bottino Cristina; Pende Daniela; Biassoni Roberto; Moretta Alessandro
Cellular and molecular basis of natural killer and natural killer-like activity.
Immunology letters 2003;88(2):89-93.
2003: Moretta Lorenzo; Ferlazzo Guido; Mingari Maria Cristina; Melioli Giovanni; Moretta Alessandro
Update on natural killer cells: cross-talk with dendritic cells and role in the cure of acute myeloid leukemias.
Cancer journal (Sudbury, Mass.) 2003;9(4):232-7.
2003: Cantoni Claudia; Ponassi Marco; Biassoni Roberto; Conte Romana; Spallarossa Andrea; Moretta Alessandro; Moretta Lorenzo; Bolognesi Martino; Bordo Domenico
The three-dimensional structure of the human NK cell receptor NKp44, a triggering partner in natural cytotoxicity.
Structure (London, England : 1993) 2003;11(6):725-34.
2003: Della Chiesa Mariella; Vitale Massimo; Carlomagno Simona; Ferlazzo Guido; Moretta Lorenzo; Moretta Alessandro
The natural killer cell-mediated killing of autologous dendritic cells is confined to a cell subset expressing CD94/NKG2A, but lacking inhibitory killer Ig-like receptors.
European journal of immunology 2003;33(6):1657-66.
2003: Moretta Lorenzo; Ferlazzo Guido; Mingari Maria Cristina; Melioli Giovanni; Moretta Alessandro
Human natural killer cell function and their interactions with dendritic cells.
Vaccine 2003;21 Suppl 2():S38-42.
2003: Augugliaro Raffaella; Parolini Silvia; Castriconi Roberta; Marcenaro Emanuela; Cantoni Claudia; Nanni Marina; Moretta Lorenzo; Moretta Alessandro; Bottino Cristina
Selective cross-talk among natural cytotoxicity receptors in human natural killer cells.
European journal of immunology 2003;33(5):1235-41.
2003: Castriconi Roberta; Cantoni Claudia; Della Chiesa Mariella; Vitale Massimo; Marcenaro Emanuela; Conte Romana; Biassoni Roberto; Bottino Cristina; Moretta Lorenzo; Moretta Alessandro
Transforming growth factor beta 1 inhibits expression of NKp30 and NKG2D receptors: consequences for the NK-mediated killing of dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):4120-5.
2003: Moretta Lorenzo; Romagnani Chiara; Pietra Gabriella; Moretta Alessandro; Mingari Maria Cristina
NK-CTLs, a novel HLA-E-restricted T-cell subset.
Trends in immunology 2003;24(3):136-43.
2003: Ferlazzo Guido; Morandi Barbara; D'Agostino Antonella; Meazza Raffaella; Melioli Giovanni; Moretta Alessandro; Moretta Lorenzo
The interaction between NK cells and dendritic cells in bacterial infections results in rapid induction of NK cell activation and in the lysis of uninfected dendritic cells.
European journal of immunology 2003;33(2):306-13.
2002: Moretta Lorenzo; Biassoni Roberto; Bottino Cristina; Cantoni Claudia; Pende Daniela; Mingari Maria Cristina; Moretta Alessandro
Human NK cells and their receptors.
Microbes and infection / Institut Pasteur 2002;4(15):1539-44.
2002: Moretta Alessandro
Natural killer cells and dendritic cells: rendezvous in abused tissues.
Nature reviews. Immunology 2002;2(12):957-64.
2002: Pende Daniela; Rivera Paola; Marcenaro Stefania; Chang Chien-Chung; Biassoni Roberto; Conte Romana; Kubin Marek; Cosman David; Ferrone Soldano; Moretta Lorenzo; Moretta Alessandro
Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytotoxicity.
Cancer research 2002;62(21):6178-86.
2002: Cantoni Claudia; Ponassi Marco; Biassoni Roberto; Conte Romana; Spallarossa Andrea; Moretta Alessandro; Moretta Lorenzo; Bolognesi Martino; Bordo Domenico
Crystallization and preliminary crystallographic characterization of the extracellular Ig-like domain of human natural killer cell activating receptor NKp44.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 10 Pt 2):1843-5.
2002: Romagnani Chiara; Pietra Gabriella; Falco Michela; Millo Enrico; Mazzarino Paola; Biassoni Roberto; Moretta Alessandro; Moretta Lorenzo; Mingari Maria Cristina
Identification of HLA-E-specific alloreactive T lymphocytes: a cell subset that undergoes preferential expansion in mixed lymphocyte culture and displays a broad cytolytic activity against allogeneic cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(17):11328-33.
2002: Costello R T; Sivori S; Mallet F; Sainty D; Arnoulet C; Reviron D; Gastaut J-A; Moretta A; Olive D
A novel mechanism of antitumor response involving the expansion of CD3+/CD56+ large granular lymphocytes triggered by a tumor-expressed activating ligand.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(5):855-60.
2002: Costello Régis T; Sivori Simona; Marcenaro Emanuela; Lafage-Pochitaloff Marina; Mozziconacci Marie-Joelle; Reviron Denis; Gastaut Jean-Albert; Pende Daniela; Olive Daniel; Moretta Alessandro
Defective expression and function of natural killer cell-triggering receptors in patients with acute myeloid leukemia.
Blood 2002;99(10):3661-7.
2002: Moretta Lorenzo; Bottino Cristina; Pende Daniela; Mingari Maria Cristina; Biassoni Roberto; Moretta Alessandro
Human natural killer cells: their origin, receptors and function.
European journal of immunology 2002;32(5):1205-11.
2002: Sivori Simona; Falco Michela; Marcenaro Emanuela; Parolini Silvia; Biassoni Roberto; Bottino Cristina; Moretta Lorenzo; Moretta Alessandro
Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4526-31.
2002: Vitale Massimo; Zimmer Jacques; Castriconi Roberta; Hanau Daniel; Donato Lionel; Bottino Cristina; Moretta Lorenzo; de la Salle Henri; Moretta Alessandro
Analysis of natural killer cells in TAP2-deficient patients: expression of functional triggering receptors and evidence for the existence of inhibitory receptor(s) that prevent lysis of normal autologous cells.
Blood 2002;99(5):1723-9.
2002: Biassoni Roberto; Bottino Cristina; Cantoni Claudia; Moretta Alessandro
Human natural killer receptors and their ligands.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2002;Chapter 14():Unit 14.10.
2002: Moretta Alessandro; Bottino Cristina; Mingari Maria Cristina; Biassoni Roberto; Moretta Lorenzo
What is a natural killer cell?
Nature immunology 2002;3(1):6-8.
2001: Moretta A; Bottino C; Parolini S; Moretta L; Biassoni R; Notarangelo L D
Cellular and molecular pathogenesis of X-linked lymphoproliferative disease.
Current opinion in allergy and clinical immunology 2001;1(6):513-7.
2001: De Maria A; Biassoni R; Fogli M; Rizzi M; Cantoni C; Costa P; Conte R; Mavilio D; Ensoli B; Cafaro A; Moretta A; Moretta L
Identification, molecular cloning and functional characterization of NKp46 and NKp30 natural cytotoxicity receptors in Macaca fascicularis NK cells.
European journal of immunology 2001;31(12):3546-56.
2001: Moretta A; Bottino C; Sivori S; Marcenaro E; Castriconi R; Della Chiesa M; Carlomagno S; Augugliaro R; Nanni M; Vitale M; Millo R
Natural killer lymphocytes: "null cells" no more.
Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia 2001;106(4):335-42.
2001: Bottino C; Falco M; Parolini S; Marcenaro E; Augugliaro R; Sivori S; Landi E; Biassoni R; Notarangelo L D; Moretta L; Moretta A
NTB-A [correction of GNTB-A], a novel SH2D1A-associated surface molecule contributing to the inability of natural killer cells to kill Epstein-Barr virus-infected B cells in X-linked lymphoproliferative disease.
The Journal of experimental medicine 2001;194(3):235-46.
2001: Biassoni R; Cantoni C; Pende D; Sivori S; Parolini S; Vitale M; Bottino C; Moretta A
Human natural killer cell receptors and co-receptors.
Immunological reviews 2001;181():203-14.
2001: Pende D; Cantoni C; Rivera P; Vitale M; Castriconi R; Marcenaro S; Nanni M; Biassoni R; Bottino C; Moretta A; Moretta L
Role of NKG2D in tumor cell lysis mediated by human NK cells: cooperation with natural cytotoxicity receptors and capability of recognizing tumors of nonepithelial origin.
European journal of immunology 2001;31(4):1076-86.
2001: Vely F; Peyrat M; Couedel C; Morcet J; Halary F; Davodeau F; Romagne F; Scotet E; Saulquin X; Houssaint E; Schleinitz N; Moretta A; Vivier E; Bonneville M
Regulation of inhibitory and activating killer-cell Ig-like receptor expression occurs in T cells after termination of TCR rearrangements.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(4):2487-94.
2001: Vitale M; Falco M; Castriconi R; Parolini S; Zambello R; Semenzato G; Biassoni R; Bottino C; Moretta L; Moretta A
Identification of NKp80, a novel triggering molecule expressed by human NK cells.
European journal of immunology 2001;31(1):233-42.
2001: Bottino C; Parolini S; Biassoni R; Falco M; Notarangelo L; Moretta A
X-linked lymphoproliferative disease: the dark side of 2b4 function.
Advances in experimental medicine and biology 2001;495():63-7.
2001: Moretta A; Bottino C; Vitale M; Pende D; Cantoni C; Mingari M C; Biassoni R; Moretta L
Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis.
Annual review of immunology 2001;19():197-223.
2000: Biassoni R; Cantoni C; Falco M; Pende D; Millo R; Moretta L; Bottino C; Moretta A
Human natural killer cell activating receptors.
Molecular immunology 2000;37(17):1015-24.
2000: Bottino C; Augugliaro R; Castriconi R; Nanni M; Biassoni R; Moretta L; Moretta A
Analysis of the molecular mechanism involved in 2B4-mediated NK cell activation: evidence that human 2B4 is physically and functionally associated with the linker for activation of T cells.
European journal of immunology 2000;30(12):3718-22.
2000: Bottino C; Falco M; Sivori S; Moretta L; Moretta A; Biassoni R
Identification and molecular characterization of a natural mutant of the p50.2/KIR2DS2 activating NK receptor that fails to mediate NK cell triggering.
European journal of immunology 2000;30(12):3569-74.
2000: Sivori S; Parolini S; Marcenaro E; Millo R; Bottino C; Moretta A
Triggering receptors involved in natural killer cell-mediated cytotoxicity against choriocarcinoma cell lines.
Human immunology 2000;61(11):1055-8.
2000: Moretta L; Biassoni R; Bottino C; Mingari M C; Moretta A
Human NK-cell receptors.
Immunology today 2000;21(9):420-2.
2000: Parolini S; Bottino C; Falco M; Augugliaro R; Giliani S; Franceschini R; Ochs H D; Wolf H; Bonnefoy J Y; Biassoni R; Moretta L; Notarangelo L D; Moretta A
X-linked lymphoproliferative disease. 2B4 molecules displaying inhibitory rather than activating function are responsible for the inability of natural killer cells to kill Epstein-Barr virus-infected cells.
The Journal of experimental medicine 2000;192(3):337-46.
2000: Sivori S; Parolini S; Marcenaro E; Castriconi R; Pende D; Millo R; Moretta A
Involvement of natural cytotoxicity receptors in human natural killer cell-mediated lysis of neuroblastoma and glioblastoma cell lines.
Journal of neuroimmunology 2000;107(2):220-5.
2000: Moretta A; Biassoni R; Bottino C; Mingari M C; Moretta L
Natural cytotoxicity receptors that trigger human NK-cell-mediated cytolysis.
Immunology today 2000;21(5):228-34.
2000: Sivori S; Parolini S; Falco M; Marcenaro E; Biassoni R; Bottino C; Moretta L; Moretta A
2B4 functions as a co-receptor in human NK cell activation.
European journal of immunology 2000;30(3):787-93.
2000: Bottino C; Biassoni R; Millo R; Moretta L; Moretta A
The human natural cytotoxicity receptors (NCR) that induce HLA class I-independent NK cell triggering.
Human immunology 2000;61(1):1-6.
1999: Vitale C; Romagnani C; Falco M; Ponte M; Vitale M; Moretta A; Bacigalupo A; Moretta L; Mingari M C
Engagement of p75/AIRM1 or CD33 inhibits the proliferation of normal or leukemic myeloid cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):15091-6.
1999: Pende D; Parolini S; Pessino A; Sivori S; Augugliaro R; Morelli L; Marcenaro E; Accame L; Malaspina A; Biassoni R; Bottino C; Moretta L; Moretta A
Identification and molecular characterization of NKp30, a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells.
The Journal of experimental medicine 1999;190(10):1505-16.
1999: Cantoni C; Bottino C; Augugliaro R; Morelli L; Marcenaro E; Castriconi R; Vitale M; Pende D; Sivori S; Millo R; Biassoni R; Moretta L; Moretta A
Molecular and functional characterization of IRp60, a member of the immunoglobulin superfamily that functions as an inhibitory receptor in human NK cells.
European journal of immunology 1999;29(10):3148-59.
1999: Falco M; Biassoni R; Bottino C; Vitale M; Sivori S; Augugliaro R; Moretta L; Moretta A
Identification and molecular cloning of p75/AIRM1, a novel member of the sialoadhesin family that functions as an inhibitory receptor in human natural killer cells.
The Journal of experimental medicine 1999;190(6):793-802.
1999: Cantoni C; Falco M; Pessino A; Moretta A; Moretta L; Biassoni R
P49, a putative HLA-G1 specific inhibitory NK receptor belonging to the immunoglobulin Superfamily.
Journal of reproductive immunology 1999;43(2):157-65.
1999: Falco M; Cantoni C; Bottino C; Moretta A; Biassoni R
Identification of the rat homologue of the human NKp46 triggering receptor.
Immunology letters 1999;68(2-3):411-4.
1999: Sivori S; Pende D; Bottino C; Marcenaro E; Pessino A; Biassoni R; Moretta L; Moretta A
NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells.
European journal of immunology 1999;29(5):1656-66.
1999: Ponte M; Cantoni C; Biassoni R; Tradori-Cappai A; Bentivoglio G; Vitale C; Bertone S; Moretta A; Moretta L; Mingari M C
Inhibitory receptors sensing HLA-G1 molecules in pregnancy: decidua-associated natural killer cells express LIR-1 and CD94/NKG2A and acquire p49, an HLA-G1-specific receptor.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(10):5674-9.
1999: Zimmer J; Donato L; Hanau D; Cazenave J P; Moretta A; Tongio M M; de la Salle H
Inefficient protection of human TAP-deficient fibroblasts from autologous NK cell-mediated lysis by cytokines inducing HLA class I expression.
European journal of immunology 1999;29(4):1286-91.
1999: Biassoni R; Pessino A; Bottino C; Pende D; Moretta L; Moretta A
The murine homologue of the human NKp46, a triggering receptor involved in the induction of natural cytotoxicity.
European journal of immunology 1999;29(3):1014-20.
1999: Cantoni C; Bottino C; Vitale M; Pessino A; Augugliaro R; Malaspina A; Parolini S; Moretta L; Moretta A; Biassoni R
NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily.
The Journal of experimental medicine 1999;189(5):787-96.
1999: Biassoni R; Bottino C; Millo R; Moretta L; Moretta A
Natural killer cell-mediated recognition of human trophoblast.
Seminars in cancer biology 1999;9(1):13-8.
1999: Vitale M; Castriconi R; Parolini S; Pende D; Hsu M L; Moretta L; Cosman D; Moretta A
The leukocyte Ig-like receptor (LIR)-1 for the cytomegalovirus UL18 protein displays a broad specificity for different HLA class I alleles: analysis of LIR-1 + NK cell clones.
International immunology 1999;11(1):29-35.
1999: Moretta A; Bottino C; Millo R; Biassoni R
HLA-specific and non-HLA-specific human NK receptors.
Current topics in microbiology and immunology 1999;244():69-84.
1998: Pessino A; Sivori S; Bottino C; Malaspina A; Morelli L; Moretta L; Biassoni R; Moretta A
Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity.
The Journal of experimental medicine 1998;188(5):953-60.
1998: Pende D; Accame L; Pareti L; Mazzocchi A; Moretta A; Parmiani G; Moretta L
The susceptibility to natural killer cell-mediated lysis of HLA class I-positive melanomas reflects the expression of insufficient amounts of different HLA class I alleles.
European journal of immunology 1998;28(8):2384-94.
1998: Vitale M; Bottino C; Sivori S; Sanseverino L; Castriconi R; Marcenaro E; Augugliaro R; Moretta L; Moretta A
NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysis.
The Journal of experimental medicine 1998;187(12):2065-72.
1998: Mingari M C; Moretta A; Moretta L
Regulation of KIR expression in human T cells: a safety mechanism that may impair protective T-cell responses.
Immunology today 1998;19(4):153-7.
1998: Mingari M C; Ponte M; Bertone S; Schiavetti F; Vitale C; Bellomo R; Moretta A; Moretta L
HLA class I-specific inhibitory receptors in human T lymphocytes: interleukin 15-induced expression of CD94/NKG2A in superantigen- or alloantigen-activated CD8+ T cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(3):1172-7.
1998: Cantoni C; Biassoni R; Pende D; Sivori S; Accame L; Pareti L; Semenzato G; Moretta L; Moretta A; Bottino C
The activating form of CD94 receptor complex: CD94 covalently associates with the Kp39 protein that represents the product of the NKG2-C gene.
European journal of immunology 1998;28(1):327-38.
1998: Le Dréan E; Vély F; Olcese L; Cambiaggi A; Guia S; Krystal G; Gervois N; Moretta A; Jotereau F; Vivier E
Inhibition of antigen-induced T cell response and antibody-induced NK cell cytotoxicity by NKG2A: association of NKG2A with SHP-1 and SHP-2 protein-tyrosine phosphatases.
European journal of immunology 1998;28(1):264-76.
1998: Zimmer J; Donato L; Hanau D; Cazenave J P; Tongio M M; Moretta A; de la Salle H
Activity and phenotype of natural killer cells in peptide transporter (TAP)-deficient patients (type I bare lymphocyte syndrome).
The Journal of experimental medicine 1998;187(1):117-22.
1998: Moretta A; Sivori S; Ponte M; Mingari M C; Moretta L
Stimulatory receptors in NK and T cells.
Current topics in microbiology and immunology 1998;230():15-23.
1997: Moretta A; Parolini S; Castriconi R; Bottino C; Vitale M; Sivori S; Millo R
Function and specificity of human natural killer cell receptors.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 1997;24(6):455-68.
1997: Biassoni R; Pessino A; Malaspina A; Cantoni C; Bottino C; Sivori S; Moretta L; Moretta A
Role of amino acid position 70 in the binding affinity of p50.1 and p58.1 receptors for HLA-Cw4 molecules.
European journal of immunology 1997;27(12):3095-9.
1997: Halary F; Peyrat M A; Champagne E; Lopez-Botet M; Moretta A; Moretta L; Vié H; Fournié J J; Bonneville M
Control of self-reactive cytotoxic T lymphocytes expressing gamma delta T cell receptors by natural killer inhibitory receptors.
European journal of immunology 1997;27(11):2812-21.
1997: Moretta A; Moretta L
HLA class I specific inhibitory receptors.
Current opinion in immunology 1997;9(5):694-701.
1997: Sivori S; Vitale M; Morelli L; Sanseverino L; Augugliaro R; Bottino C; Moretta L; Moretta A
p46, a novel natural killer cell-specific surface molecule that mediates cell activation.
The Journal of experimental medicine 1997;186(7):1129-36.
1997: Vély F; Olivero S; Olcese L; Moretta A; Damen J E; Liu L; Krystal G; Cambier J C; Daëron M; Vivier E
Differential association of phosphatases with hematopoietic co-receptors bearing immunoreceptor tyrosine-based inhibition motifs.
European journal of immunology 1997;27(8):1994-2000.
1997: Pende D; Sivori S; Accame L; Pareti L; Falco M; Geraghty D; Le Bouteiller P; Moretta L; Moretta A
HLA-G recognition by human natural killer cells. Involvement of CD94 both as inhibitory and as activating receptor complex.
European journal of immunology 1997;27(8):1875-80.
1997: Cambiaggi A; Verthuy C; Naquet P; Romagné F; Ferrier P; Biassoni R; Moretta A; Moretta L; Vivier E
Natural killer cell acceptance of H-2 mismatch bone marrow grafts in transgenic mice expressing HLA-Cw3 specific killer cell inhibitory receptor.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(15):8088-92.
1997: Mingari M C; Vitale C; Cantoni C; Bellomo R; Ponte M; Schiavetti F; Bertone S; Moretta A; Moretta L
Interleukin-15-induced maturation of human natural killer cells from early thymic precursors: selective expression of CD94/NKG2-A as the only HLA class I-specific inhibitory receptor.
European journal of immunology 1997;27(6):1374-80.
1997: Olcese L; Cambiaggi A; Semenzato G; Bottino C; Moretta A; Vivier E
Human killer cell activatory receptors for MHC class I molecules are included in a multimeric complex expressed by natural killer cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(11):5083-6.
1997: Bléry M; Delon J; Trautmann A; Cambiaggi A; Olcese L; Biassoni R; Moretta L; Chavrier P; Moretta A; Daëron M; Vivier E
Reconstituted killer cell inhibitory receptors for major histocompatibility complex class I molecules control mast cell activation induced via immunoreceptor tyrosine-based activation motifs.
The Journal of biological chemistry 1997;272(14):8989-96.
1997: Moretta A; Biassoni R; Bottino C; Pende D; Vitale M; Poggi A; Mingari M C; Moretta L
Major histocompatibility complex class I-specific receptors on human natural killer and T lymphocytes.
Immunological reviews 1997;155():105-17.
1996: Sivori S; Vitale M; Sanseverino L; Parolini S; Barbaresi M; Bottino C; Moretta A
Inhibitory CD94 molecules identified by the Z199 monoclonal antibody recognize different HLA-class I molecules.
Transplantation proceedings 1996;28(6):3199-203.
1996: Pérez-Villar J J; Carretero M; Navarro F; Melero I; Rodríguez A; Bottino C; Moretta A; López-Botet M
Biochemical and serologic evidence for the existence of functionally distinct forms of the CD94 NK cell receptor.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(12):5367-74.
1996: Sivori S; Vitale M; Bottino C; Marcenaro E; Sanseverino L; Parolini S; Moretta L; Moretta A
CD94 functions as a natural killer cell inhibitory receptor for different HLA class I alleles: identification of the inhibitory form of CD94 by the use of novel monoclonal antibodies.
European journal of immunology 1996;26(10):2487-92.
1996: Bottino C; Sivori S; Vitale M; Cantoni C; Falco M; Pende D; Morelli L; Augugliaro R; Semenzato G; Biassoni R; Moretta L; Moretta A
A novel surface molecule homologous to the p58/p50 family of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation.
European journal of immunology 1996;26(8):1816-24.
1996: Pende D; Biassoni R; Cantoni C; Verdiani S; Falco M; di Donato C; Accame L; Bottino C; Moretta A; Moretta L
The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer.
The Journal of experimental medicine 1996;184(2):505-18.
1996: Olcese L; Lang P; Vély F; Cambiaggi A; Marguet D; Bléry M; Hippen K L; Biassoni R; Moretta A; Moretta L; Cambier J C; Vivier E
Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(12):4531-4.
1996: Poggi A; Costa P; Morelli L; Cantoni C; Pella N; Spada F; Biassoni R; Nanni L; Revello V; Tomasello E; Mingari M C; Moretta A; Moretta L
Expression of human NKRP1A by CD34+ immature thymocytes: NKRP1A-mediated regulation of proliferation and cytolytic activity.
European journal of immunology 1996;26(6):1266-72.
1996: Vitale M; Sivori S; Pende D; Augugliaro R; Di Donato C; Amoroso A; Malnati M; Bottino C; Moretta L; Moretta A
Physical and functional independency of p70 and p58 natural killer (NK) cell receptors for HLA class I: their role in the definition of different groups of alloreactive NK cell clones.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(4):1453-7.
1996: Biassoni R; Cantoni C; Falco M; Verdiani S; Bottino C; Vitale M; Conte R; Poggi A; Moretta A; Moretta L
The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions.
The Journal of experimental medicine 1996;183(2):645-50.
1995: Moretta A; Sivori S; Vitale M; Pende D; Morelli L; Augugliaro R; Bottino C; Moretta L
Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells.
The Journal of experimental medicine 1995;182(3):875-84.
1995: Pérez-Villar J J; Melero I; Rodríguez A; Carretero M; Aramburu J; Sivori S; Orengo A M; Moretta A; López-Botet M
Functional ambivalence of the Kp43 (CD94) NK cell-associated surface antigen.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(11):5779-88.
1995: Wagtmann N; Biassoni R; Cantoni C; Verdiani S; Malnati M S; Vitale M; Bottino C; Moretta L; Moretta A; Long E O
Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains.
Immunity 1995;2(5):439-49.
1995: Vitale M; Sivori S; Pende D; Moretta L; Moretta A
Coexpression of two functionally independent p58 inhibitory receptors in human natural killer cell clones results in the inability to kill all normal allogeneic target cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(8):3536-40.
1995: Ciccone E; Pende D; Nanni L; Di Donato C; Viale O; Beretta A; Vitale M; Sivori S; Moretta A; Moretta L
General role of HLA class I molecules in the protection of target cells from lysis by natural killer cells: evidence that the free heavy chains of class I molecules are not sufficient to mediate the protective effect.
International immunology 1995;7(3):393-400.
1995: Poggi A; Pella N; Morelli L; Spada F; Revello V; Sivori S; Augugliaro R; Moretta L; Moretta A
p40, a novel surface molecule involved in the regulation of the non-major histocompatibility complex-restricted cytolytic activity in humans.
European journal of immunology 1995;25(2):369-76.
1995: Malnati M S; Peruzzi M; Parker K C; Biddison W E; Ciccone E; Moretta A; Long E O
Peptide specificity in the recognition of MHC class I by natural killer cell clones.
Science (New York, N.Y.) 1995;267(5200):1016-8.
1994: Bottino C; Vitale M; Olcese L; Sivori S; Morelli L; Augugliaro R; Ciccone E; Moretta L; Moretta A
The human natural killer cell receptor for major histocompatibility complex class I molecules. Surface modulation of p58 molecules and their linkage to CD3 zeta chain, Fc epsilon RI gamma chain and the p56lck kinase.
European journal of immunology 1994;24(10):2527-34.
1994: Moretta A; Vitale M; Sivori S; Bottino C; Morelli L; Augugliaro R; Barbaresi M; Pende D; Ciccone E; Lopez-Botet M; Moretta L
Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles.
The Journal of experimental medicine 1994;180(2):545-55.
1994: Moretta L; Ciccone E; Poggi A; Mingari M C; Moretta A
Ontogeny, specific functions and receptors of human natural killer cells.
Immunology letters 1994;40(2):83-8.
1994: Ciccone E; Pende D; Vitale M; Nanni L; Di Donato C; Bottino C; Morelli L; Viale O; Amoroso A; Moretta A
Self class I molecules protect normal cells from lysis mediated by autologous natural killer cells.
European journal of immunology 1994;24(4):1003-6.
1994: Vitale M; Sivori S; Sanseverino L; Barbaresi M; Morelli L; Olcese L; Agugliano R; Bottino C; Moretta A
Negative signalling via the P58/NKR for HLA.C alleles.
European journal of histochemistry : EJH 1994;38 Suppl 1():69-76.
1994: Moretta L; Ciccone E; Mingari M C; Biassoni R; Moretta A
Human natural killer cells: origin, clonality, specificity, and receptors.
Advances in immunology 1994;55():341-80.
1993: Poggi A; Pardi R; Pella N; Morelli L; Sivori S; Vitale M; Revello V; Moretta A; Moretta L
CD45-mediated regulation of LFA1 function in human natural killer cells. Anti-CD45 monoclonal antibodies inhibit the calcium mobilization induced via LFA1 molecules.
European journal of immunology 1993;23(10):2454-63.
1993: Malnati M S; Lusso P; Ciccone E; Moretta A; Moretta L; Long E O
Recognition of virus-infected cells by natural killer cell clones is controlled by polymorphic target cell elements.
The Journal of experimental medicine 1993;178(3):961-9.
1993: Moretta A; Vitale M; Bottino C; Orengo A M; Morelli L; Augugliaro R; Barbaresi M; Ciccone E; Moretta L
P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities.
The Journal of experimental medicine 1993;178(2):597-604.
1993: Galandrini R; Albi N; Tripodi G; Zarcone D; Terenzi A; Moretta A; Grossi C E; Velardi A
Antibodies to CD44 trigger effector functions of human T cell clones.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(10):4225-35.
1992: Ciccone E; Pende D; Viale O; Than A; Di Donato C; Orengo A M; Biassoni R; Verdiani S; Amoroso A; Moretta A
Involvement of HLA class I alleles in natural killer (NK) cell-specific functions: expression of HLA-Cw3 confers selective protection from lysis by alloreactive NK clones displaying a defined specificity (specificity 2).
The Journal of experimental medicine 1992;176(4):963-71.
1992: Moretta L; Ciccone E; Pende D; Viale O; Di Donato C; Tripodi G; Orengo A M; Guardiola J; Moretta A
Existence of a natural killer (NK) cell repertoire for (allo)antigen recognition: definition of five distinct NK-determined allospecificities in humans.
Pharmacological research : the official journal of the Italian Pharmacological Society 1992;26 Suppl 2():98-9.
1992: Zarcone D; Viale O; Cerruti G; Tenca C; Malorni W; Arancia G; Iosi F; Galandrini R; Velardi A; Moretta A
Antibodies to adhesion molecules inhibit the lytic function of MHC-unrestricted cytotoxic cells by preventing their activation.
Cellular immunology 1992;143(2):389-404.
1992: Ciccone E; Pende D; Viale O; Di Donato C; Tripodi G; Orengo A M; Guardiola J; Moretta A; Moretta L
Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition: definition of five distinct NK-determined allospecificities in humans.
The Journal of experimental medicine 1992;175(3):709-18.
1992: Ciccone E; Moretta A; Moretta L
Specific functions of human NK cells.
Immunology letters 1992;31(2):99-103.
1992: Moretta L; Ciccone E; Pende D; Tripodi G; Bottino C; Moretta A
Human natural killer cells: clonally distributed specific functions and triggering surface molecules.
Laboratory investigation; a journal of technical methods and pathology 1992;66(2):138-42.
1992: Moretta A; Bottino C; Tripodi G; Vitale M; Pende D; Morelli L; Augugliaro R; Barbaresi M; Ciccone E; Millo R
Novel surface molecules involved in human NK cell activation and triggering of the lytic machinery.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1992;7():6-10.
1992: Grossi C E; Ciccone E; Zeromski J; Moretta A; Moretta L
Functional and morphologic characterization of human T lymphocytes expressing the TCR gamma/delta.
Biotherapy (Dordrecht, Netherlands) 1992;5(1):1-9.
1991: Moretta A; Poggi A; Pende D; Tripodi G; Orengo A M; Pella N; Augugliaro R; Bottino C; Ciccone E; Moretta L
CD69-mediated pathway of lymphocyte activation: anti-CD69 monoclonal antibodies trigger the cytolytic activity of different lymphoid effector cells with the exception of cytolytic T lymphocytes expressing T cell receptor alpha/beta.
The Journal of experimental medicine 1991;174(6):1393-8.
1991: Mingari M C; Poggi A; Biassoni R; Bellomo R; Ciccone E; Pella N; Morelli L; Verdiani S; Moretta A; Moretta L
In vitro proliferation and cloning of CD3- CD16+ cells from human thymocyte precursors.
The Journal of experimental medicine 1991;174(1):21-6.
1991: Fagioli M; Carè A; Ciccone E; Moretta L; Moretta A; Meccia E; Testa U; Falini B; Grignani F; Peschle C
Molecular heterogeneity of the 1.0-kb T beta transcript in natural killer and gamma/delta lymphocytes.
European journal of immunology 1991;21(6):1529-34.
1991: Moretta L; Ciccone E; Ferrini S; Pelicci P G; Mingari M C; Zeromski J; Bottino C; Grossi C; Moretta A
Molecular and cellular analysis of human T lymphocytes expressing gamma delta T-cell receptor.
Immunological reviews 1991;120():117-35.
1991: Arancia G; Malorni W; Iosi F; Zarcone D; Cerruti G; Favre A; Zeromski J; Grossi C E; Moretta A
Morphological features of cloned lymphocytes expressing gamma/delta T cell receptors.
European journal of immunology 1991;21(1):173-8.
1991: Arancia G; Malorni W; Iosi F; Zarcone D; Cerruti G; Moretta A; Grossi C E
Growth features of T-cell receptor gamma/delta-positive cell clones.
Immunologic research 1991;10(3-4):331-3.
1991: Ciccone E; Viale O; Pende D; Malnati M; Moretta A; Moretta L
Specificity of human T lymphocytes expressing a gamma/delta T cell antigen receptor. Recognition of a polymorphic determinant of HLA class I molecules by a gamma/delta+ clone.
Current topics in microbiology and immunology 1991;173():223-7.
1990: Moretta A; Bottino C; Pende D; Tripodi G; Tambussi G; Viale O; Orengo A; Barbaresi M; Merli A; Ciccone E
Identification of four subsets of human CD3-CD16+ natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition.
The Journal of experimental medicine 1990;172(6):1589-98.
1990: Ciccone E; Colonna M; Viale O; Pende D; Di Donato C; Reinharz D; Amoroso A; Jeannet M; Guardiola J; Moretta A
Susceptibility or resistance to lysis by alloreactive natural killer cells is governed by a gene in the human major histocompatibility complex between BF and HLA-B.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(24):9794-7.
1990: Moretta A; Bottino C; Pende D; Tripodi G; Orengo A M; Millo R; Pelicci P G; Ciccone E; Moretta L
Human T lymphocytes expressing TCR gamma/delta.
Research in immunology 1990;141(7):630-5.
1990: Fagioli M; Ciccone E; Bottino C; Falini B; Grignani F; Moretta A; Moretta L; Pelicci P G
The C gamma 1-encoded disulphide-linked and the C gamma 2-encoded nondisulphide-linked forms of the gamma/delta heterodimer use different gamma and delta variable regions.
Blood 1990;76(2):279-84.
1990: Ciccone E; Pende D; Viale O; Tambussi G; Ferrini S; Biassoni R; Longo A; Guardiola J; Moretta A; Moretta L
Specific recognition of human CD3-CD16+ natural killer cells requires the expression of an autosomic recessive gene on target cells.
The Journal of experimental medicine 1990;172(1):47-52.
1990: Carè A; Pelicci P G; Meccia E; Fagioli M; Testa U; Ciccone E; Moretta A; Moretta L; Peschle C
Natural killer cells carry the germ-line configuration of the T cell receptor delta chain gene and heterogeneously express six distinct delta transcripts.
European journal of immunology 1990;20(4):939-42.
1990: Moretta A; Tambussi G; Bottino C; Tripodi G; Merli A; Ciccone E; Pantaleo G; Moretta L
A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function.
The Journal of experimental medicine 1990;171(3):695-714.
1990: Ciccone E; Grossi C E; Malorni W; Arancia G; Mingari M C; Ferrini S; Moretta A; Moretta L
Human lymphocytes expressing a TCR gamma/delta.
Annali dell'Istituto superiore di sanità 1990;26(3-4):349-56.
1990: Fagioli M; Carè A; Ciccone E; Moretta L; Moretta A; Testa U; Falini B; Grignani F; Peschle C; Pelicci P G
Molecular studies on LAK cells.
Annali dell'Istituto superiore di sanità 1990;26(3-4):357-68.
1989: Moretta A; Tambussi G; Ciccone E; Pende D; Melioli G; Moretta L
CD16 surface molecules regulate the cytolytic function of CD3CD16+ human natural killer cells.
International journal of cancer. Journal international du cancer 1989;44(4):727-30.
1989: Moretta A; Ciccone E; Pantaleo G; Tambussi G; Bottino C; Melioli G; Mingari M C; Moretta L
Surface molecules involved in the activation and regulation of T or natural killer lymphocytes in humans.
Immunological reviews 1989;111():145-75.
1989: Malorni W; Arancia G; Iosi F; Donelli G; Zarcone D; Moretta A; Grossi C E
A scanning electron microscopy analysis of human cytotoxic cell subsets and of their mode of conjugation with tumor cell targets.
Scanning microscopy 1989;3(3):919-26; discussion 926-7.
1989: Moretta L; Ciccone E; Mingari M C; Zeromski J; Bottino C; Ferrini S; Tambussi G; Melioli G; Grossi C E; Moretta A
Phenotypic and functional characterization of human T lymphocytes expressing a gamma/delta T cell antigen receptor.
Clinical and experimental rheumatology 1989;7 Suppl 3():S9-14.
1989: Ferrini S; Prigione I; Mammoliti S; Colnaghi M I; Ménard S; Moretta A; Moretta L
Re-targeting of human lymphocytes expressing the T-cell receptor gamma/delta to ovarian carcinoma cells by the use of bispecific monoclonal antibodies.
International journal of cancer. Journal international du cancer 1989;44(2):245-50.
1989: Ciccone E; Viale O; Pende D; Malnati M; Battista Ferrara G; Barocci S; Moretta A; Moretta L
Specificity of human T lymphocytes expressing a gamma/delta T cell antigen receptor. Recognition of a polymorphic determinant of HLA class I molecules by a gamma/delta clone.
European journal of immunology 1989;19(7):1267-71.
1989: Ferrini S; Zarcone D; Viale M; Cerruti G; Millo R; Moretta A; Grossi C E
Morphologic and functional characterization of human peripheral blood T cells expressing the T cell receptor gamma/delta.
European journal of immunology 1989;19(7):1183-8.
1989: Ferrini S; Prigione I; Bottino C; Ciccone E; Tambussi G; Mammoliti S; Moretta L; Moretta A
Monoclonal antibodies which react with the T cell receptor gamma/delta recognize different subsets of CD3+WT31- T lymphocytes.
European journal of immunology 1989;19(1):57-61.
1989: Mingari M C; Tambussi G; Bottino C; Varese P; Moretta A
Partial inefficiency of T cell receptors gamma/delta composed of a heavy (55-kD) gamma chain to mediate cell activation upon binding to specific monoclonal antibodies.
La Ricerca in clinica e in laboratorio 1989;19(1):39-44.
1989: Moretta L; Ciccone E; Mingari M C; Bottino C; Ferrini S; Tambussi G; Melioli G; Grossi C E; Moretta A
Human T lymphocytes expressing gamma/delta T cell antigen receptor.
Clinical immunology and immunopathology 1989;50(1 Pt 2):S117-23.
1989: Melioli G; Ciccone E; Mingari M C; Pende D; Viale O; Tambussi G; Merli A; Moretta A; Moretta L
Specific recognition by CD3- NK cells: a limiting dilution analysis of the frequency of alloreactive CD3- lymphocyte precursors.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1989;4():56-7.
1989: Ferrini S; Prigione I; Mammoliti S; Colnaghi M I; Menard S; Moretta A; Moretta L
Retargeting of T-cell-receptor gamma/delta+ lymphocytes against tumor cells by bispecific monoclonal antibodies. Induction of cytolytic activity and lymphokine production.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1989;4():53-5.
1989: Moretta A; Ciccone E; Tambussi G; Bottino C; Viale O; Pende D; Santoni A; Mingari M C
Surface molecules involved in CD3-negative NK cell function. A novel molecule which regulates the activation of a subset of human NK cells.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1989;4():48-52.
1988: Moretta A; Bottino C; Ciccone E; Tambussi G; Mingari M C; Ferrini S; Casorati G; Varese P; Viale O; Migone N
Human peripheral blood lymphocytes bearing T cell receptor gamma/delta. Expression of CD8 differentiation antigen correlates with the expression of the 55-kD, C gamma 2-encoded gamma chain.
The Journal of experimental medicine 1988;168(6):2349-54.
1988: Ciccone E; Viale O; Pende D; Malnati M; Biassoni R; Melioli G; Moretta A; Long E O; Moretta L
Specific lysis of allogeneic cells after activation of CD3- lymphocytes in mixed lymphocyte culture.
The Journal of experimental medicine 1988;168(6):2403-8.
1988: Mingari M C; Varese P; Bottino C; Melioli G; Moretta A; Moretta L
Clonal analysis of CD4-CD8- human thymocytes expressing a T cell receptor gamma/delta chain. Direct evidence for the de novo expression of CD8 surface antigen and of cytolytic activity against tumor targets.
European journal of immunology 1988;18(11):1831-4.
1988: Bottino C; Tambussi G; Ferrini S; Ciccone E; Varese P; Mingari M C; Moretta L; Moretta A
Two subsets of human T lymphocytes expressing gamma/delta antigen receptor are identifiable by monoclonal antibodies directed to two distinct molecular forms of the receptor.
The Journal of experimental medicine 1988;168(2):491-505.
1988: Pantaleo G; Zocchi M R; Ferrini S; Poggi A; Tambussi G; Bottino C; Moretta L; Moretta A
Human cytolytic cell clones lacking surface expression of T cell receptor alpha/beta or gamma/delta. Evidence that surface structures other than CD3 or CD2 molecules are required for signal transduction.
The Journal of experimental medicine 1988;168(1):13-24.
1988: Ciccone E; Ferrini S; Bottino C; Viale O; Prigione I; Pantaleo G; Tambussi G; Moretta A; Moretta L
A monoclonal antibody specific for a common determinant of the human T cell receptor gamma/delta directly activates CD3+WT31- lymphocytes to express their functional program(s).
The Journal of experimental medicine 1988;168(1):1-11.
1988: Ciccone E; Viale O; Bottino C; Pende D; Migone N; Casorati G; Tambussi G; Moretta A; Moretta L
Antigen recognition by human T cell receptor gamma-positive lymphocytes. Specific lysis of allogeneic cells after activation in mixed lymphocyte culture.
The Journal of experimental medicine 1988;167(4):1517-22.
1988: Carrel S; Moretta A; Pantaleo G; Tambussi G; Isler P; Perussia B; Cerottini J C
Stimulation and proliferation of CD4+ peripheral blood T lymphocytes induced by an anti-CD4 monoclonal antibody.
European journal of immunology 1988;18(3):333-9.
1988: Biassoni R; Ferrini S; Prigione I; Moretta A; Long E O
CD3-negative lymphokine-activated cytotoxic cells express the CD3 epsilon gene.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(5):1685-9.
1987: De Maria A; Malnati M; Moretta A; Pende D; Bottino C; Casorati G; Cottafava F; Melioli G; Mingari M C; Migone N
CD3+4-8-WT31-(T cell receptor gamma+) cells and other unusual phenotypes are frequently detected among spontaneously interleukin 2-responsive T lymphocytes present in the joint fluid in juvenile rheumatoid arthritis. A clonal analysis.
European journal of immunology 1987;17(12):1815-9.
1987: Pantaleo G; Ferrini S; Zocchi M R; Bottino C; Biassoni R; Moretta L; Moretta A
Analysis of signal transducing mechanisms in CD3+ CD4- CD8- cells expressing the putative T cell receptor gamma gene product.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(11):3580-4.
1987: Mingari M C; Ferrini S; Pende D; Bottino C; Prigione I; Moretta A; Moretta L
Phenotypic and functional analysis of human CD3+ and CD3- clones with "lymphokine-activated killer" (LAK) activity. Frequent occurrence of CD3+ LAK clones which produce interleukin-2.
International journal of cancer. Journal international du cancer 1987;40(4):495-8.
1987: Moretta L; Pende D; Bottino C; Migone N; Ciccone E; Ferrini S; Mingari M C; Moretta A
Human CD3+4-8-WT31- T lymphocyte populations expressing the putative T cell receptor gamma-gene product. A limiting dilution and clonal analysis.
European journal of immunology 1987;17(9):1229-34.
1987: Bottino C; Ferrini S; Ciccone E; Prigione I; Pende D; Mingari M C; Moretta L; Moretta A
Analysis of CD3-associated molecules in CD4- 8- human T cell clones lacking the typical alpha/beta T cell receptor.
La Ricerca in clinica e in laboratorio 1987;17(2):125-9.

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