Lorenzo Moretta

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Anatomy

Chemicals & Drugs

Physiology

Living Beings

Mice

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Marcenaro Emanuela; Cantoni Claudia; Pesce Silvia; Prato Carola; Pende Daniela; Agaugué Sophie; Moretta Lorenzo; Moretta Alessandro
Uptake of CCR7 and acquisition of migratory properties by human KIR+ NK cells interacting with monocyte-derived DC or EBV cell lines: regulation by KIR/HLA-class I interaction.
Balsamo Mirna; Zambello Renato; Teramo Antonella; Pedrazzi Marco; Sparatore Bianca; Scordamaglia Francesca; Pende Daniela; Mingari Maria Cristina; Moretta Lorenzo; Moretta Alessandro; Semenzato Gianpietro; Vitale Massimo
Analysis of NK cell/DC interaction in NK-type lymphoproliferative disease of granular lymphocytes (LDGL): role of DNAM-1 and NKp30.
Bozzano Federica; Costa Paola; Passalacqua Giovanni; Dodi Ferdinando; Ravera Silvia; Pagano Gabriella; Canonica Giorgio W; Moretta Lorenzo; De Maria Andrea
Functionally relevant decreases in activatory receptor expression on NK cells are associated with pulmonary tuberculosis in vivo and persist after successful treatment.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Lorenzo Moretta (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Marcenaro Emanuela; Cantoni Claudia; Pesce Silvia; Prato Carola; Pende Daniela; Agaugué Sophie; Moretta Lorenzo; Moretta Alessandro
Uptake of CCR7 and acquisition of migratory properties by human KIR+ NK cells interacting with monocyte-derived DC or EBV cell lines: regulation by KIR/HLA-class I interaction.
Blood 2009;114(19):4108-16.
2009: Balsamo Mirna; Zambello Renato; Teramo Antonella; Pedrazzi Marco; Sparatore Bianca; Scordamaglia Francesca; Pende Daniela; Mingari Maria Cristina; Moretta Lorenzo; Moretta Alessandro; Semenzato Gianpietro; Vitale Massimo
Analysis of NK cell/DC interaction in NK-type lymphoproliferative disease of granular lymphocytes (LDGL): role of DNAM-1 and NKp30.
Experimental hematology 2009;37(10):1167-75.
2009: Bozzano Federica; Costa Paola; Passalacqua Giovanni; Dodi Ferdinando; Ravera Silvia; Pagano Gabriella; Canonica Giorgio W; Moretta Lorenzo; De Maria Andrea
Functionally relevant decreases in activatory receptor expression on NK cells are associated with pulmonary tuberculosis in vivo and persist after successful treatment.
International immunology 2009;21(7):779-91.
2009: Spaggiari Grazia Maria; Abdelrazik Heba; Becchetti Flavio; Moretta Lorenzo
MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: central role of MSC-derived prostaglandin E2.
Blood 2009;113(26):6576-83.
2009: Morandi Barbara; Mortara Lorenzo; Carrega Paolo; Cantoni Claudia; Costa Gregorio; Accolla Roberto S; Mingari Maria Cristina; Ferrini Silvano; Moretta Lorenzo; Ferlazzo Guido
NK cells provide helper signal for CD8+ T cells by inducing the expression of membrane-bound IL-15 on DCs.
International immunology 2009;21(5):599-606.
2009: Castriconi Roberta; Daga Antonio; Dondero Alessandra; Zona Gianluigi; Poliani Pietro Luigi; Melotti Alice; Griffero Fabrizio; Marubbi Daniela; Spaziante Renato; Bellora Francesca; Moretta Lorenzo; Moretta Alessandro; Corte Giorgio; Bottino Cristina
NK cells recognize and kill human glioblastoma cells with stem cell-like properties.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(6):3530-9.
2009: De Maria Andrea; Ugolotti Elisabetta; Rutjens Erik; Mazza Stefania; Radic Luana; Faravelli Alessandro; Koopman Gerrit; Di Marco Eddi; Costa Paola; Ensoli Barbara; Cafaro Aurelio; Mingari Maria Cristina; Moretta Lorenzo; Heeney Jonathan; Biassoni Roberto
NKp44 expression, phylogenesis and function in non-human primate NK cells.
International immunology 2009;21(3):245-55.
2009: Costa Paola; Sivori Simona; Bozzano Federica; Martini Isabella; Moretta Alessandro; Moretta Lorenzo; De Maria Andrea
IFN-alpha-mediated increase in cytolytic activity of maturing NK cell upon exposure to HSV-infected myelomonocytes.
European journal of immunology 2009;39(1):147-58.
2009: Pietra Gabriella; Romagnani Chiara; Moretta Lorenzo; Mingari Maria Cristina
HLA-E and HLA-E-bound peptides: recognition by subsets of NK and T cells.
Current pharmaceutical design 2009;15(28):3336-44.
2008: Moretta L; Locatelli F; Moretta A
Alloreactive natural killer cells in targeting high-risk leukaemias.
Annals of the rheumatic diseases 2008;67 Suppl 3():iii39-43.
2008: Vacca Paola; Cantoni Claudia; Prato Carola; Fulcheri Ezio; Moretta Alessandro; Moretta Lorenzo; Mingari Maria Cristina
Regulatory role of NKp44, NKp46, DNAM-1 and NKG2D receptors in the interaction between NK cells and trophoblast cells. Evidence for divergent functional profiles of decidual versus peripheral NK cells.
International immunology 2008;20(11):1395-405.
2008: Uccelli Antonio; Moretta Lorenzo; Pistoia Vito
Mesenchymal stem cells in health and disease.
Nature reviews. Immunology 2008;8(9):726-36.
2008: Marcenaro Emanuela; Ferranti Bruna; Falco Michela; Moretta Lorenzo; Moretta Alessandro
Human NK cells directly recognize Mycobacterium bovis via TLR2 and acquire the ability to kill monocyte-derived DC.
International immunology 2008;20(9):1155-67.
2008: Agaugué Sophie; Marcenaro Emanuela; Ferranti Bruna; Moretta Lorenzo; Moretta Alessandro
Human natural killer cells exposed to IL-2, IL-12, IL-18, or IL-4 differently modulate priming of naive T cells by monocyte-derived dendritic cells.
Blood 2008;112(5):1776-83.
2008: Moretta Alessandro; Locatelli Franco; Moretta Lorenzo
Human NK cells: from HLA class I-specific killer Ig-like receptors to the therapy of acute leukemias.
Immunological reviews 2008;224():58-69.
2008: Della Chiesa Mariella; Romeo Elisa; Falco Michela; Balsamo Mirna; Augugliaro Raffaella; Moretta Lorenzo; Bottino Cristina; Moretta Alessandro; Vitale Massimo
Evidence that the KIR2DS5 gene codes for a surface receptor triggering natural killer cell function.
European journal of immunology 2008;38(8):2284-9.
2008: Carrega Paolo; Morandi Barbara; Costa Roberta; Frumento Guido; Forte Giuseppe; Altavilla Giuseppe; Ratto Giovanni Battista; Mingari Maria Cristina; Moretta Lorenzo; Ferlazzo Guido
Natural killer cells infiltrating human nonsmall-cell lung cancer are enriched in CD56 bright CD16(-) cells and display an impaired capability to kill tumor cells.
Cancer 2008;112(4):863-75.
2008: Spaggiari Grazia Maria; Capobianco Andrea; Abdelrazik Heba; Becchetti Flavio; Mingari Maria Cristina; Moretta Lorenzo
Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2.
Blood 2008;111(3):1327-33.
2008: Moretta A; Marcenaro E; Parolini S; Ferlazzo G; Moretta L
NK cells at the interface between innate and adaptive immunity.
Cell death and differentiation 2008;15(2):226-33.
2008: Giuliani Massimo; Giron-Michel Julien; Negrini Simone; Vacca Paola; Durali Deniz; Caignard Anne; Le Bousse-Kerdiles Caroline; Chouaib Salem; Devocelle Aurore; Bahri Rajia; Durrbach Antoine; Taoufik Yassine; Ferrini Silvano; Croce Michela; Mingari Maria Cristina; Moretta Lorenzo; Azzarone Bruno
Generation of a novel regulatory NK cell subset from peripheral blood CD34+ progenitors promoted by membrane-bound IL-15.
PloS one 2008;3(5):e2241.
2007: Moretta Lorenzo
NK cell-mediated immune response against cancer.
Surgical oncology 2007;16 Suppl 1():S3-5.
2007: Sivori Simona; Falco Michela; Carlomagno Simona; Romeo Elisa; Moretta Lorenzo; Moretta Alessandro
Heterogeneity of TLR3 mRNA transcripts and responsiveness to poly (I:C) in human NK cells derived from different donors.
International immunology 2007;19(12):1341-8.
2007: Castriconi Roberta; Dondero Alessandra; Negri Francesca; Bellora Francesca; Nozza Paolo; Carnemolla Barbara; Raso Alessandro; Moretta Lorenzo; Moretta Alessandro; Bottino Cristina
Both CD133+ and CD133- medulloblastoma cell lines express ligands for triggering NK receptors and are susceptible to NK-mediated cytotoxicity.
European journal of immunology 2007;37(11):3190-6.
2007: Castriconi Roberta; Dondero Alessandra; Cilli Michele; Ognio Emanuela; Pezzolo Annalisa; De Giovanni Barbara; Gambini Claudio; Pistoia Vito; Moretta Lorenzo; Moretta Alessandro; Corrias Maria Valeria
Human NK cell infusions prolong survival of metastatic human neuroblastoma-bearing NOD/scid mice.
Cancer immunology, immunotherapy : CII 2007;56(11):1733-42.
2007: Castriconi Roberta; Dondero Alessandra; Cantoni Claudia; Della Chiesa Mariella; Prato Carola; Nanni Marina; Fiorini Maurilia; Notarangelo Lucia; Parolini Silvia; Moretta Lorenzo; Notarangelo Luigi; Moretta Alessandro; Bottino Cristina
Functional characterization of natural killer cells in type I leukocyte adhesion deficiency.
Blood 2007;109(11):4873-81.
2007: Uccelli Antonio; Pistoia Vito; Moretta Lorenzo
Mesenchymal stem cells: a new strategy for immunosuppression?
Trends in immunology 2007;28(5):219-26.
2007: Chiossone Laura; Vitale Chiara; Cottalasso Francesca; Moretti Sara; Azzarone Bruno; Moretta Lorenzo; Mingari Maria Cristina
Molecular analysis of the methylprednisolone-mediated inhibition of NK-cell function: evidence for different susceptibility of IL-2- versus IL-15-activated NK cells.
Blood 2007;109(9):3767-75.
2007: Romagnani Chiara; Juelke Kerstin; Falco Michela; Morandi Barbara; D'Agostino Antonella; Costa Roberta; Ratto Giovanni; Forte Giuseppe; Carrega Paolo; Lui Gabrielle; Conte Romana; Strowig Till; Moretta Alessandro; Münz Christian; Thiel Andreas; Moretta Lorenzo; Ferlazzo Guido
CD56brightCD16- killer Ig-like receptor- NK cells display longer telomeres and acquire features of CD56dim NK cells upon activation.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(8):4947-55.
2007: Millo E; Pietra G; Armirotti A; Vacca P; Mingari M C; Moretta L; Damonte G
Purification and HPLC-MS analysis of a naturally processed HCMV-derived peptide isolated from the HEK-293T/HLA-E+/Ul40+ cell transfectants and presented at the cell surface in the context of HLA-E.
Journal of immunological methods 2007;322(1-2):128-36.
2007: De Maria Andrea; Fogli Manuela; Mazza Stefania; Basso Monica; Picciotto Antonio; Costa Paola; Congia Sonia; Mingari Maria Cristina; Moretta Lorenzo
Increased natural cytotoxicity receptor expression and relevant IL-10 production in NK cells from chronically infected viremic HCV patients.
European journal of immunology 2007;37(2):445-55.
2007: Rutjens Erik; Mazza Stefania; Biassoni Roberto; Koopman Gerrit; Radic Luana; Fogli Manuela; Costa Paola; Mingari Maria Cristina; Moretta Lorenzo; Heeney Jonathan; De Maria Andrea
Differential NKp30 inducibility in chimpanzee NK cells and conserved NK cell phenotype and function in long-term HIV-1-infected animals.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(3):1702-12.
2006: Vacca Paola; Pietra Gabriella; Falco Michela; Romeo Elisa; Bottino Cristina; Bellora Francesca; Prefumo Federico; Fulcheri Ezio; Venturini Pier Luigi; Costa Mauro; Moretta Alessandro; Moretta Lorenzo; Mingari Maria Cristina
Analysis of natural killer cells isolated from human decidua: Evidence that 2B4 (CD244) functions as an inhibitory receptor and blocks NK-cell function.
Blood 2006;108(13):4078-85.
2006: Della Chiesa Mariella; Carlomagno Simona; Frumento Guido; Balsamo Mirna; Cantoni Claudia; Conte Romana; Moretta Lorenzo; Moretta Alessandro; Vitale Massimo
The tryptophan catabolite L-kynurenine inhibits the surface expression of NKp46- and NKG2D-activating receptors and regulates NK-cell function.
Blood 2006;108(13):4118-25.
2006: Della Chiesa Mariella; Romagnani Chiara; Thiel Andreas; Moretta Lorenzo; Moretta Alessandro
Multidirectional interactions are bridging human NK cells with plasmacytoid and monocyte-derived dendritic cells during innate immune responses.
Blood 2006;108(12):3851-8.
2006: Santoro A; Cannella S; Bossi G; Gallo F; Trizzino A; Pende D; Dieli F; Bruno G; Stinchcombe J C; Micalizzi C; De Fusco C; Danesino C; Moretta L; Notarangelo L D; Griffiths G M; Aricò M
Novel Munc13-4 mutations in children and young adult patients with haemophagocytic lymphohistiocytosis.
Journal of medical genetics 2006;43(12):953-60.
2006: Uccelli Antonio; Moretta Lorenzo; Pistoia Vito
Immunoregulatory function of mesenchymal stem cells.
European journal of immunology 2006;36(10):2566-73.
2006: Marcenaro Stefania; Gallo Federico; Martini Stefania; Santoro Alessandra; Griffiths Gillian M; Aricó Maurizio; Moretta Lorenzo; Pende Daniela
Analysis of natural killer-cell function in familial hemophagocytic lymphohistiocytosis (FHL): defective CD107a surface expression heralds Munc13-4 defect and discriminates between genetic subtypes of the disease.
Blood 2006;108(7):2316-23.
2006: Sivori Simona; Carlomagno Simona; Moretta Lorenzo; Moretta Alessandro
Comparison of different CpG oligodeoxynucleotide classes for their capability to stimulate human NK cells.
European journal of immunology 2006;36(4):961-7.
2006: Hoare Hilary L; Sullivan Lucy C; Pietra Gabriella; Clements Craig S; Lee Eleanor J; Ely Lauren K; Beddoe Travis; Falco Michela; Kjer-Nielsen Lars; Reid Hugh H; McCluskey James; Moretta Lorenzo; Rossjohn Jamie; Brooks Andrew G
Structural basis for a major histocompatibility complex class Ib-restricted T cell response.
Nature immunology 2006;7(3):256-64.
2006: Pende Daniela; Castriconi Roberta; Romagnani Paola; Spaggiari Grazia Maria; Marcenaro Stefania; Dondero Alessandra; Lazzeri Elena; Lasagni Laura; Martini Stefania; Rivera Paola; Capobianco Andrea; Moretta Lorenzo; Moretta Alessandro; Bottino Cristina
Expression of the DNAM-1 ligands, Nectin-2 (CD112) and poliovirus receptor (CD155), on dendritic cells: relevance for natural killer-dendritic cell interaction.
Blood 2006;107(5):2030-6.
2006: Spaggiari Grazia Maria; Capobianco Andrea; Becchetti Stelvio; Mingari Maria Cristina; Moretta Lorenzo
Mesenchymal stem cell-natural killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation.
Blood 2006;107(4):1484-90.
2005: Moretta Alessandro; Marcenaro Emanuela; Sivori Simona; Della Chiesa Mariella; Vitale Massimo; Moretta Lorenzo
Early liaisons between cells of the innate immune system in inflamed peripheral tissues.
Trends in immunology 2005;26(12):668-75.
2005: Mazzarino Paola; Pietra Gabriella; Vacca Paola; Falco Michela; Colau Didier; Coulie Pierre; Moretta Lorenzo; Mingari Maria Cristina
Identification of effector-memory CMV-specific T lymphocytes that kill CMV-infected target cells in an HLA-E-restricted fashion.
European journal of immunology 2005;35(11):3240-7.
2005: Giron-Michel Julien; Giuliani Massimo; Fogli Manuela; Brouty-Boyé Danièle; Ferrini Silvano; Baychelier Florence; Eid Pierre; Lebousse-Kerdilès Caroline; Durali Deniz; Biassoni Roberto; Charpentier Bernard; Vasquez Aimé; Chouaib Salem; Caignard Anne; Moretta Lorenzo; Azzarone Bruno
Membrane-bound and soluble IL-15/IL-15Ralpha complexes display differential signaling and functions on human hematopoietic progenitors.
Blood 2005;106(7):2302-10.
2005: Moretta Lorenzo; Bottino Cristina; Pende Daniela; Vitale Massimo; Mingari Maria Cristina; Moretta Alessandro
Human natural killer cells: Molecular mechanisms controlling NK cell activation and tumor cell lysis.
Immunology letters 2005;100(1):7-13.
2005: Romagnani Chiara; Della Chiesa Mariella; Kohler Siegfried; Moewes Beate; Radbruch Andreas; Moretta Lorenzo; Moretta Alessandro; Thiel Andreas
Activation of human NK cells by plasmacytoid dendritic cells and its modulation by CD4+ T helper cells and CD4+ CD25hi T regulatory cells.
European journal of immunology 2005;35(8):2452-8.
2005: Trambas Christina; Gallo Federico; Pende Daniela; Marcenaro Stefania; Moretta Lorenzo; De Fusco Carmela; Santoro Alessandra; Notarangelo Luigi; Arico Maurizio; Griffiths Gillian M
A single amino acid change, A91V, leads to conformational changes that can impair processing to the active form of perforin.
Blood 2005;106(3):932-7.
2005: Vitale Massimo; Della Chiesa Mariella; Carlomagno Simona; Pende Daniela; Aricò Maurizio; Moretta Lorenzo; Moretta Alessandro
NK-dependent DC maturation is mediated by TNFalpha and IFNgamma released upon engagement of the NKp30 triggering receptor.
Blood 2005;106(2):566-71.
2005: Mingari Maria Cristina; Pietra Gabriella; Moretta Lorenzo
Human cytolytic T lymphocytes expressing HLA class-I-specific inhibitory receptors.
Current opinion in immunology 2005;17(3):312-9.
2005: Biassoni Roberto; Fogli Manuela; Cantoni Claudia; Costa Paola; Conte Romana; Koopman Gerrit; Cafaro Aurelio; Ensoli Barbara; Moretta Alessandro; Moretta Lorenzo; De Maria Andrea
Molecular and functional characterization of NKG2D, NKp80, and NKG2C triggering NK cell receptors in rhesus and cynomolgus macaques: monitoring of NK cell function during simian HIV infection.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(9):5695-705.
2005: Marcenaro Emanuela; Della Chiesa Mariella; Bellora Francesca; Parolini Silvia; Millo Romano; Moretta Lorenzo; Moretta Alessandro
IL-12 or IL-4 prime human NK cells to mediate functionally divergent interactions with dendritic cells or tumors.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(7):3992-8.
2005: Pende Daniela; Spaggiari Grazia Maria; Marcenaro Stefania; Martini Stefania; Rivera Paola; Capobianco Andrea; Falco Michela; Lanino Edoardo; Pierri Ivana; Zambello Renato; Bacigalupo Andrea; Mingari Maria Cristina; Moretta Alessandro; Moretta Lorenzo
Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112).
Blood 2005;105(5):2066-73.
2005: Pende Daniela; Bottino Cristina; Castriconi Roberta; Cantoni Claudia; Marcenaro Stefania; Rivera Paola; Spaggiari Grazia M; Dondero Alessandra; Carnemolla Barbara; Reymond Nicolas; Mingari Maria Cristina; Lopez Marc; Moretta Lorenzo; Moretta Alessandro
PVR (CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis.
Molecular immunology 2005;42(4):463-9.
2005: Vitale Chiara; Chiossone Laura; Morreale Giuseppe; Lanino Edoardo; Cottalasso Francesca; Moretti Sara; Dini Giorgio; Moretta Lorenzo; Mingari Maria Cristina
Human natural killer cells undergoing in vivo differentiation after allogeneic bone marrow transplantation: analysis of the surface expression and function of activating NK receptors.
Molecular immunology 2005;42(4):405-11.
2004: Castriconi Roberta; Dondero Alessandra; Corrias Maria Valeria; Lanino Edoardo; Pende Daniela; Moretta Lorenzo; Bottino Cristina; Moretta Alessandro
Natural killer cell-mediated killing of freshly isolated neuroblastoma cells: critical role of DNAX accessory molecule-1-poliovirus receptor interaction.
Cancer research 2004;64(24):9180-4.
2004: Moretta Lorenzo; Bottino Cristina; Pende Daniela; Vitale Massimo; Mingari Maria Cristina; Moretta Alessandro
Different checkpoints in human NK-cell activation.
Trends in immunology 2004;25(12):670-6.
2004: Ferlazzo Guido; Pack Maggi; Thomas Dolca; Paludan Casper; Schmid Dorothee; Strowig Till; Bougras Gwenola; Muller William A; Moretta Lorenzo; Münz Christian
Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(47):16606-11.
2004: Swaminathan Chittoor P; Wais Neelowfar; Vyas Vinay V; Velikovsky Carlos A; Moretta Alessandro; Moretta Lorenzo; Biassoni Roberto; Mariuzza Roy A; Dimasi Nazzareno
Entropically assisted carbohydrate recognition by a natural killer cell-surface receptor.
Chembiochem : a European journal of chemical biology 2004;5(11):1571-5.
2004: Vitale Chiara; Chiossone Laura; Cantoni Claudia; Morreale Giuseppe; Cottalasso Francesca; Moretti Sara; Pistorio Angela; Haupt Riccardo; Lanino Edoardo; Dini Giorgio; Moretta Lorenzo; Mingari Maria Cristina
The corticosteroid-induced inhibitory effect on NK cell function reflects down-regulation and/or dysfunction of triggering receptors involved in natural cytotoxicity.
European journal of immunology 2004;34(11):3028-38.
2004: Castriconi Roberta; Dondero Alessandra; Augugliaro Raffaella; Cantoni Claudia; Carnemolla Barbara; Sementa Angela Rita; Negri Francesca; Conte Romana; Corrias Maria Valeria; Moretta Lorenzo; Moretta Alessandro; Bottino Cristina
Identification of 4Ig-B7-H3 as a neuroblastoma-associated molecule that exerts a protective role from an NK cell-mediated lysis.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(34):12640-5.
2004: Fogli Manuela; Costa Paola; Murdaca Giuseppe; Setti Maurizio; Mingari Maria Cristina; Moretta Lorenzo; Moretta Alessandro; De Maria Andrea
Significant NK cell activation associated with decreased cytolytic function in peripheral blood of HIV-1-infected patients.
European journal of immunology 2004;34(8):2313-21.
2004: Sivori Simona; Falco Michela; Della Chiesa Mariella; Carlomagno Simona; Vitale Massimo; Moretta Lorenzo; Moretta Alessandro
CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(27):10116-21.
2004: Vitale Massimo; Della Chiesa Mariella; Carlomagno Simona; Romagnani Chiara; Thiel Andreas; Moretta Lorenzo; Moretta Alessandro
The small subset of CD56brightCD16- natural killer cells is selectively responsible for both cell proliferation and interferon-gamma production upon interaction with dendritic cells.
European journal of immunology 2004;34(6):1715-22.
2004: Falco Michela; Marcenaro Emanuela; Romeo Elisa; Bellora Francesca; Marras Daniele; Vély Frédéric; Ferracci Géraldine; Moretta Lorenzo; Moretta Alessandro; Bottino Cristina
Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells.
European journal of immunology 2004;34(6):1663-72.
2004: Romagnani Chiara; Pietra Gabriella; Falco Michela; Mazzarino Paola; Moretta Lorenzo; Mingari Maria Cristina
HLA-E-restricted recognition of human cytomegalovirus by a subset of cytolytic T lymphocytes.
Human immunology 2004;65(5):437-45.
2004: Vitale Chiara; Chiossone Laura; Morreale Giuseppe; Lanino Edoardo; Cottalasso Francesca; Moretti Sara; Dini Giorgio; Moretta Lorenzo; Mingari Maria Cristina
Analysis of the activating receptors and cytolytic function of human natural killer cells undergoing in vivo differentiation after allogeneic bone marrow transplantation.
European journal of immunology 2004;34(2):455-60.
2004: Dimasi Nazzareno; Moretta Alessandro; Moretta Lorenzo; Biassoni Roberto; Mariuzza Roy A
Structure of the saccharide-binding domain of the human natural killer cell inhibitory receptor p75/AIRM1.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 2):401-3.
2004: Lozupone Francesco; Pende Daniela; Burgio Vito Lelio; Castelli Chiara; Spada Massimo; Venditti Massimo; Luciani Francesca; Lugini Luana; Federici Cristina; Ramoni Carlo; Rivoltini Licia; Parmiani Giorgio; Belardelli Filippo; Rivera Paola; Marcenaro Stefania; Moretta Lorenzo; Fais Stefano
Effect of human natural killer and gammadelta T cells on the growth of human autologous melanoma xenografts in SCID mice.
Cancer research 2004;64(1):378-85.
2004: Dimasi Nazzareno; Moretta Lorenzo; Biassoni Roberto
Structure of the Ly49 family of natural killer (NK) cell receptors and their interaction with MHC class I molecules.
Immunologic research 2004;30(1):95-104.
2003: Ponassi Marco; Cantoni Claudia; Biassoni Roberto; Conte Romana; Spallarossa Andrea; Moretta Alessandro; Moretta Lorenzo; Bolognesi Martino; Bordo Domenico
Expression and crystallographic characterization of the extracellular domain of human natural killer cell triggering receptor NKp46.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 12):2259-61.
2003: Mavilio Domenico; Benjamin Janet; Daucher Marybeth; Lombardo Gabriella; Kottilil Shyam; Planta Marie A; Marcenaro Emanuela; Bottino Cristina; Moretta Lorenzo; Moretta Alessandro; Fauci Anthony S
Natural killer cells in HIV-1 infection: dichotomous effects of viremia on inhibitory and activating receptors and their functional correlates.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):15011-6.
2003: Sivori Simona; Cantoni Claudia; Parolini Silvia; Marcenaro Emanuela; Conte Romana; Moretta Lorenzo; Moretta Alessandro
IL-21 induces both rapid maturation of human CD34+ cell precursors towards NK cells and acquisition of surface killer Ig-like receptors.
European journal of immunology 2003;33(12):3439-47.
2003: Pietra Gabriella; Romagnani Chiara; Mazzarino Paola; Millo Enrico; Moretta Lorenzo; Mingari Maria Cristina
Comparative analysis of NK- or NK-CTL-mediated lysis of immature or mature autologous dendritic cells.
European journal of immunology 2003;33(12):3427-32.
2003: Marcenaro Emanuela; Augugliaro Raffaella; Falco Michela; Castriconi Roberta; Parolini Silvia; Sivori Simona; Romeo Elisa; Millo Romano; Moretta Lorenzo; Bottino Cristina; Moretta Alessandro
CD59 is physically and functionally associated with natural cytotoxicity receptors and activates human NK cell-mediated cytotoxicity.
European journal of immunology 2003;33(12):3367-76.
2003: Biassoni R; Cantoni Claudia; Marras D; Giron-Michel J; Falco Michela; Moretta L; Dimasi N
Human natural killer cell receptors: insights into their molecular function and structure.
Journal of cellular and molecular medicine 2003;7(4):376-87.
2003: Dimasi Nazzareno; Moretta Lorenzo; Biassoni Roberto; Mariuzza Roy A
Expression, crystallization and preliminary crystallographic analysis of the extracellular IgV-like domain of the human natural killer cell inhibitory receptor p75/AIRM1.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 10):1856-8.
2003: Pietra Gabriella; Romagnani Chiara; Mazzarino Paola; Falco Michela; Millo Enrico; Moretta Alessandro; Moretta Lorenzo; Mingari Maria Cristina
HLA-E-restricted recognition of cytomegalovirus-derived peptides by human CD8+ cytolytic T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(19):10896-901.
2003: Ponassi Marco; Cantoni Claudia; Biassoni Roberto; Conte Romana; Spallarossa Andrea; Pesce Alessandra; Moretta Alessandro; Moretta Lorenzo; Bolognesi Martino; Bordo Domenico
Structure of the human NK cell triggering receptor NKp46 ectodomain.
Biochemical and biophysical research communications 2003;309(2):317-23.
2003: De Maria Andrea; Fogli Manuela; Costa Paola; Murdaca Giuseppe; Puppo Francesco; Mavilio Domenico; Moretta Alessandro; Moretta Lorenzo
The impaired NK cell cytolytic function in viremic HIV-1 infection is associated with a reduced surface expression of natural cytotoxicity receptors (NKp46, NKp30 and NKp44).
European journal of immunology 2003;33(9):2410-8.
2003: Bottino Cristina; Castriconi Roberta; Pende Daniela; Rivera Paola; Nanni Marina; Carnemolla Barbara; Cantoni Claudia; Grassi Jessica; Marcenaro Stefania; Reymond Nicolas; Vitale Massimo; Moretta Lorenzo; Lopez Marc; Moretta Alessandro
Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule.
The Journal of experimental medicine 2003;198(4):557-67.
2003: Moretta Lorenzo; Mingari Maria Cristina; Bottino Cristina; Pende Daniela; Biassoni Roberto; Moretta Alessandro
Cellular and molecular basis of natural killer and natural killer-like activity.
Immunology letters 2003;88(2):89-93.
2003: Moretta Lorenzo; Ferlazzo Guido; Mingari Maria Cristina; Melioli Giovanni; Moretta Alessandro
Update on natural killer cells: cross-talk with dendritic cells and role in the cure of acute myeloid leukemias.
Cancer journal (Sudbury, Mass.) 2003;9(4):232-7.
2003: Cantoni Claudia; Ponassi Marco; Biassoni Roberto; Conte Romana; Spallarossa Andrea; Moretta Alessandro; Moretta Lorenzo; Bolognesi Martino; Bordo Domenico
The three-dimensional structure of the human NK cell receptor NKp44, a triggering partner in natural cytotoxicity.
Structure (London, England : 1993) 2003;11(6):725-34.
2003: Della Chiesa Mariella; Vitale Massimo; Carlomagno Simona; Ferlazzo Guido; Moretta Lorenzo; Moretta Alessandro
The natural killer cell-mediated killing of autologous dendritic cells is confined to a cell subset expressing CD94/NKG2A, but lacking inhibitory killer Ig-like receptors.
European journal of immunology 2003;33(6):1657-66.
2003: Moretta Lorenzo; Ferlazzo Guido; Mingari Maria Cristina; Melioli Giovanni; Moretta Alessandro
Human natural killer cell function and their interactions with dendritic cells.
Vaccine 2003;21 Suppl 2():S38-42.
2003: Augugliaro Raffaella; Parolini Silvia; Castriconi Roberta; Marcenaro Emanuela; Cantoni Claudia; Nanni Marina; Moretta Lorenzo; Moretta Alessandro; Bottino Cristina
Selective cross-talk among natural cytotoxicity receptors in human natural killer cells.
European journal of immunology 2003;33(5):1235-41.
2003: Castriconi Roberta; Cantoni Claudia; Della Chiesa Mariella; Vitale Massimo; Marcenaro Emanuela; Conte Romana; Biassoni Roberto; Bottino Cristina; Moretta Lorenzo; Moretta Alessandro
Transforming growth factor beta 1 inhibits expression of NKp30 and NKG2D receptors: consequences for the NK-mediated killing of dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):4120-5.
2003: Moretta Lorenzo; Romagnani Chiara; Pietra Gabriella; Moretta Alessandro; Mingari Maria Cristina
NK-CTLs, a novel HLA-E-restricted T-cell subset.
Trends in immunology 2003;24(3):136-43.
2003: Ferlazzo Guido; Morandi Barbara; D'Agostino Antonella; Meazza Raffaella; Melioli Giovanni; Moretta Alessandro; Moretta Lorenzo
The interaction between NK cells and dendritic cells in bacterial infections results in rapid induction of NK cell activation and in the lysis of uninfected dendritic cells.
European journal of immunology 2003;33(2):306-13.
2003: Costa Paola; Rusconi Stefano; Fogli Manuela; Mavilio Domenico; Murdaca Giuseppe; Puppo Francesco; Mingari Maria Cristina; Galli Massimo; Moretta Lorenzo; De Maria Andrea
Low expression of inhibitory natural killer receptors in CD8 cytotoxic T lymphocytes in long-term non-progressor HIV-1-infected patients.
AIDS (London, England) 2003;17(2):257-60.
2002: Moretta Lorenzo; Biassoni Roberto; Bottino Cristina; Cantoni Claudia; Pende Daniela; Mingari Maria Cristina; Moretta Alessandro
Human NK cells and their receptors.
Microbes and infection / Institut Pasteur 2002;4(15):1539-44.
2002: Pende Daniela; Rivera Paola; Marcenaro Stefania; Chang Chien-Chung; Biassoni Roberto; Conte Romana; Kubin Marek; Cosman David; Ferrone Soldano; Moretta Lorenzo; Moretta Alessandro
Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytotoxicity.
Cancer research 2002;62(21):6178-86.
2002: Cantoni Claudia; Ponassi Marco; Biassoni Roberto; Conte Romana; Spallarossa Andrea; Moretta Alessandro; Moretta Lorenzo; Bolognesi Martino; Bordo Domenico
Crystallization and preliminary crystallographic characterization of the extracellular Ig-like domain of human natural killer cell activating receptor NKp44.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 10 Pt 2):1843-5.
2002: Romagnani Chiara; Pietra Gabriella; Falco Michela; Millo Enrico; Mazzarino Paola; Biassoni Roberto; Moretta Alessandro; Moretta Lorenzo; Mingari Maria Cristina
Identification of HLA-E-specific alloreactive T lymphocytes: a cell subset that undergoes preferential expansion in mixed lymphocyte culture and displays a broad cytolytic activity against allogeneic cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(17):11328-33.
2002: Moretta Lorenzo; Bottino Cristina; Pende Daniela; Mingari Maria Cristina; Biassoni Roberto; Moretta Alessandro
Human natural killer cells: their origin, receptors and function.
European journal of immunology 2002;32(5):1205-11.
2002: Sivori Simona; Falco Michela; Marcenaro Emanuela; Parolini Silvia; Biassoni Roberto; Bottino Cristina; Moretta Lorenzo; Moretta Alessandro
Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4526-31.
2002: Vitale Massimo; Zimmer Jacques; Castriconi Roberta; Hanau Daniel; Donato Lionel; Bottino Cristina; Moretta Lorenzo; de la Salle Henri; Moretta Alessandro
Analysis of natural killer cells in TAP2-deficient patients: expression of functional triggering receptors and evidence for the existence of inhibitory receptor(s) that prevent lysis of normal autologous cells.
Blood 2002;99(5):1723-9.
2002: Moretta Alessandro; Bottino Cristina; Mingari Maria Cristina; Biassoni Roberto; Moretta Lorenzo
What is a natural killer cell?
Nature immunology 2002;3(1):6-8.
2001: Moretta A; Bottino C; Parolini S; Moretta L; Biassoni R; Notarangelo L D
Cellular and molecular pathogenesis of X-linked lymphoproliferative disease.
Current opinion in allergy and clinical immunology 2001;1(6):513-7.
2001: Pietra G; Romagnani C; Falco M; Vitale M; Castriconi R; Pende D; Millo E; Anfossi S; Biassoni R; Moretta L; Mingari M C
The analysis of the natural killer-like activity of human cytolytic T lymphocytes revealed HLA-E as a novel target for TCR alpha/beta-mediated recognition.
European journal of immunology 2001;31(12):3687-93.
2001: De Maria A; Biassoni R; Fogli M; Rizzi M; Cantoni C; Costa P; Conte R; Mavilio D; Ensoli B; Cafaro A; Moretta A; Moretta L
Identification, molecular cloning and functional characterization of NKp46 and NKp30 natural cytotoxicity receptors in Macaca fascicularis NK cells.
European journal of immunology 2001;31(12):3546-56.
2001: Bottino C; Falco M; Parolini S; Marcenaro E; Augugliaro R; Sivori S; Landi E; Biassoni R; Notarangelo L D; Moretta L; Moretta A
NTB-A [correction of GNTB-A], a novel SH2D1A-associated surface molecule contributing to the inability of natural killer cells to kill Epstein-Barr virus-infected B cells in X-linked lymphoproliferative disease.
The Journal of experimental medicine 2001;194(3):235-46.
2001: Mingari M C; Vitale C; Romagnani C; Falco M; Moretta L
p75/AIRM1 and CD33, two sialoadhesin receptors that regulate the proliferation or the survival of normal and leukemic myeloid cells.
Immunological reviews 2001;181():260-8.
2001: Spaggiari G M; Carosio R; Pende D; Marcenaro S; Rivera P; Zocchi M R; Moretta L; Poggi A
NK cell-mediated lysis of autologous antigen-presenting cells is triggered by the engagement of the phosphatidylinositol 3-kinase upon ligation of the natural cytotoxicity receptors NKp30 and NKp46.
European journal of immunology 2001;31(6):1656-65.
2001: Costa P; Rusconi S; Mavilio D; Fogli M; Murdaca G; Pende D; Mingari M C; Galli M; Moretta L; De Maria A
Differential disappearance of inhibitory natural killer cell receptors during HAART and possible impairment of HIV-1-specific CD8 cytotoxic T lymphocytes.
AIDS (London, England) 2001;15(8):965-74.
2001: Vitale C; Romagnani C; Puccetti A; Olive D; Costello R; Chiossone L; Pitto A; Bacigalupo A; Moretta L; Mingari M C
Surface expression and function of p75/AIRM-1 or CD33 in acute myeloid leukemias: engagement of CD33 induces apoptosis of leukemic cells.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(10):5764-9.
2001: Pende D; Cantoni C; Rivera P; Vitale M; Castriconi R; Marcenaro S; Nanni M; Biassoni R; Bottino C; Moretta A; Moretta L
Role of NKG2D in tumor cell lysis mediated by human NK cells: cooperation with natural cytotoxicity receptors and capability of recognizing tumors of nonepithelial origin.
European journal of immunology 2001;31(4):1076-86.
2001: Vitale M; Falco M; Castriconi R; Parolini S; Zambello R; Semenzato G; Biassoni R; Bottino C; Moretta L; Moretta A
Identification of NKp80, a novel triggering molecule expressed by human NK cells.
European journal of immunology 2001;31(1):233-42.
2001: Mingari M C; Vitale C; Romagnani C; Falco M; Moretta L
Regulation of myeloid cell proliferation and survival by p75/AIRM1 and CD33 surface receptors.
Advances in experimental medicine and biology 2001;495():55-61.
2001: Moretta A; Bottino C; Vitale M; Pende D; Cantoni C; Mingari M C; Biassoni R; Moretta L
Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis.
Annual review of immunology 2001;19():197-223.
2000: Biassoni R; Cantoni C; Falco M; Pende D; Millo R; Moretta L; Bottino C; Moretta A
Human natural killer cell activating receptors.
Molecular immunology 2000;37(17):1015-24.
2000: Bottino C; Augugliaro R; Castriconi R; Nanni M; Biassoni R; Moretta L; Moretta A
Analysis of the molecular mechanism involved in 2B4-mediated NK cell activation: evidence that human 2B4 is physically and functionally associated with the linker for activation of T cells.
European journal of immunology 2000;30(12):3718-22.
2000: Bottino C; Falco M; Sivori S; Moretta L; Moretta A; Biassoni R
Identification and molecular characterization of a natural mutant of the p50.2/KIR2DS2 activating NK receptor that fails to mediate NK cell triggering.
European journal of immunology 2000;30(12):3569-74.
2000: Moretta L; Biassoni R; Bottino C; Mingari M C; Moretta A
Human NK-cell receptors.
Immunology today 2000;21(9):420-2.
2000: Parolini S; Bottino C; Falco M; Augugliaro R; Giliani S; Franceschini R; Ochs H D; Wolf H; Bonnefoy J Y; Biassoni R; Moretta L; Notarangelo L D; Moretta A
X-linked lymphoproliferative disease. 2B4 molecules displaying inhibitory rather than activating function are responsible for the inability of natural killer cells to kill Epstein-Barr virus-infected cells.
The Journal of experimental medicine 2000;192(3):337-46.
2000: Moretta A; Biassoni R; Bottino C; Mingari M C; Moretta L
Natural cytotoxicity receptors that trigger human NK-cell-mediated cytolysis.
Immunology today 2000;21(5):228-34.
2000: Ferlazzo G; Spaggiari G M; Semino C; Melioli G; Moretta L
Engagement of CD33 surface molecules prevents the generation of dendritic cells from both monocytes and CD34+ myeloid precursors.
European journal of immunology 2000;30(3):827-33.
2000: Sivori S; Parolini S; Falco M; Marcenaro E; Biassoni R; Bottino C; Moretta L; Moretta A
2B4 functions as a co-receptor in human NK cell activation.
European journal of immunology 2000;30(3):787-93.
2000: De Maria A; Moretta L
HLA-class I-specific inhibitory receptors in HIV-1 infection.
Human immunology 2000;61(1):74-81.
2000: Mingari M C; Ponte M; Vitale C; Bellomo R; Moretta L
Expression of HLA class I-specific inhibitory receptors in human cytolytic T lymphocytes: a regulated mechanism that controls T-cell activation and function.
Human immunology 2000;61(1):44-50.
2000: Bottino C; Biassoni R; Millo R; Moretta L; Moretta A
The human natural cytotoxicity receptors (NCR) that induce HLA class I-independent NK cell triggering.
Human immunology 2000;61(1):1-6.
2000: Vitale C; Pitto A; Benvenuto F; Ponte M; Bellomo R; Frassoni F; Mingari M C; Bacigalupo A; Moretta L
Phenotypic and functional analysis of the HLA-class I-specific inhibitory receptors of natural killer cells isolated from peripheral blood of patients undergoing bone marrow transplantation from matched unrelated donors.
The hematology journal : the official journal of the European Haematology Association / EHA 2000;1(2):136-44.
1999: Vitale C; Romagnani C; Falco M; Ponte M; Vitale M; Moretta A; Bacigalupo A; Moretta L; Mingari M C
Engagement of p75/AIRM1 or CD33 inhibits the proliferation of normal or leukemic myeloid cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):15091-6.
1999: Pende D; Parolini S; Pessino A; Sivori S; Augugliaro R; Morelli L; Marcenaro E; Accame L; Malaspina A; Biassoni R; Bottino C; Moretta L; Moretta A
Identification and molecular characterization of NKp30, a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells.
The Journal of experimental medicine 1999;190(10):1505-16.
1999: Cantoni C; Bottino C; Augugliaro R; Morelli L; Marcenaro E; Castriconi R; Vitale M; Pende D; Sivori S; Millo R; Biassoni R; Moretta L; Moretta A
Molecular and functional characterization of IRp60, a member of the immunoglobulin superfamily that functions as an inhibitory receptor in human NK cells.
European journal of immunology 1999;29(10):3148-59.
1999: Falco M; Biassoni R; Bottino C; Vitale M; Sivori S; Augugliaro R; Moretta L; Moretta A
Identification and molecular cloning of p75/AIRM1, a novel member of the sialoadhesin family that functions as an inhibitory receptor in human natural killer cells.
The Journal of experimental medicine 1999;190(6):793-802.
1999: Cantoni C; Falco M; Pessino A; Moretta A; Moretta L; Biassoni R
P49, a putative HLA-G1 specific inhibitory NK receptor belonging to the immunoglobulin Superfamily.
Journal of reproductive immunology 1999;43(2):157-65.
1999: Sivori S; Pende D; Bottino C; Marcenaro E; Pessino A; Biassoni R; Moretta L; Moretta A
NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells.
European journal of immunology 1999;29(5):1656-66.
1999: Ponte M; Cantoni C; Biassoni R; Tradori-Cappai A; Bentivoglio G; Vitale C; Bertone S; Moretta A; Moretta L; Mingari M C
Inhibitory receptors sensing HLA-G1 molecules in pregnancy: decidua-associated natural killer cells express LIR-1 and CD94/NKG2A and acquire p49, an HLA-G1-specific receptor.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(10):5674-9.
1999: Biassoni R; Pessino A; Bottino C; Pende D; Moretta L; Moretta A
The murine homologue of the human NKp46, a triggering receptor involved in the induction of natural cytotoxicity.
European journal of immunology 1999;29(3):1014-20.
1999: Cantoni C; Bottino C; Vitale M; Pessino A; Augugliaro R; Malaspina A; Parolini S; Moretta L; Moretta A; Biassoni R
NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily.
The Journal of experimental medicine 1999;189(5):787-96.
1999: Biassoni R; Bottino C; Millo R; Moretta L; Moretta A
Natural killer cell-mediated recognition of human trophoblast.
Seminars in cancer biology 1999;9(1):13-8.
1999: Vitale M; Castriconi R; Parolini S; Pende D; Hsu M L; Moretta L; Cosman D; Moretta A
The leukocyte Ig-like receptor (LIR)-1 for the cytomegalovirus UL18 protein displays a broad specificity for different HLA class I alleles: analysis of LIR-1 + NK cell clones.
International immunology 1999;11(1):29-35.
1999: Bertone S; Schiavetti F; Bellomo R; Vitale C; Ponte M; Moretta L; Mingari M C
Transforming growth factor-beta-induced expression of CD94/NKG2A inhibitory receptors in human T lymphocytes.
European journal of immunology 1999;29(1):23-9.
1998: Ponte M; Bertone S; Vitale C; Tradori-Cappai A; Bellomo R; Castriconi R; Moretta L; Mingari M C
Cytokine-induced expression of killer inhibitory receptors in human T lymphocytes.
European cytokine network 1998;9(3 Suppl):69-72.
1998: Pessino A; Sivori S; Bottino C; Malaspina A; Morelli L; Moretta L; Biassoni R; Moretta A
Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity.
The Journal of experimental medicine 1998;188(5):953-60.
1998: Pende D; Accame L; Pareti L; Mazzocchi A; Moretta A; Parmiani G; Moretta L
The susceptibility to natural killer cell-mediated lysis of HLA class I-positive melanomas reflects the expression of insufficient amounts of different HLA class I alleles.
European journal of immunology 1998;28(8):2384-94.
1998: Cantoni C; Verdiani S; Falco M; Pessino A; Cilli M; Conte R; Pende D; Ponte M; Mikaelsson M S; Moretta L; Biassoni R
p49, a putative HLA class I-specific inhibitory NK receptor belonging to the immunoglobulin superfamily.
European journal of immunology 1998;28(6):1980-90.
1998: Vitale M; Bottino C; Sivori S; Sanseverino L; Castriconi R; Marcenaro E; Augugliaro R; Moretta L; Moretta A
NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysis.
The Journal of experimental medicine 1998;187(12):2065-72.
1998: Poggi A; Costa P; Tomasello E; Moretta L
IL-12-induced up-regulation of NKRP1A expression in human NK cells and consequent NKRP1A-mediated down-regulation of NK cell activation.
European journal of immunology 1998;28(5):1611-6.
1998: Mingari M C; Moretta A; Moretta L
Regulation of KIR expression in human T cells: a safety mechanism that may impair protective T-cell responses.
Immunology today 1998;19(4):153-7.
1998: Mingari M C; Ponte M; Bertone S; Schiavetti F; Vitale C; Bellomo R; Moretta A; Moretta L
HLA class I-specific inhibitory receptors in human T lymphocytes: interleukin 15-induced expression of CD94/NKG2A in superantigen- or alloantigen-activated CD8+ T cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(3):1172-7.
1998: Cantoni C; Biassoni R; Pende D; Sivori S; Accame L; Pareti L; Semenzato G; Moretta L; Moretta A; Bottino C
The activating form of CD94 receptor complex: CD94 covalently associates with the Kp39 protein that represents the product of the NKG2-C gene.
European journal of immunology 1998;28(1):327-38.
1998: Moretta A; Sivori S; Ponte M; Mingari M C; Moretta L
Stimulatory receptors in NK and T cells.
Current topics in microbiology and immunology 1998;230():15-23.
1997: Biassoni R; Pessino A; Malaspina A; Cantoni C; Bottino C; Sivori S; Moretta L; Moretta A
Role of amino acid position 70 in the binding affinity of p50.1 and p58.1 receptors for HLA-Cw4 molecules.
European journal of immunology 1997;27(12):3095-9.
1997: Moretta A; Moretta L
HLA class I specific inhibitory receptors.
Current opinion in immunology 1997;9(5):694-701.
1997: Sivori S; Vitale M; Morelli L; Sanseverino L; Augugliaro R; Bottino C; Moretta L; Moretta A
p46, a novel natural killer cell-specific surface molecule that mediates cell activation.
The Journal of experimental medicine 1997;186(7):1129-36.
1997: Poggi A; Costa P; Zocchi M R; Moretta L
Phenotypic and functional analysis of CD4+ NKRP1A+ human T lymphocytes. Direct evidence that the NKRP1A molecule is involved in transendothelial migration.
European journal of immunology 1997;27(9):2345-50.
1997: Poggi A; Tomasello E; Revello V; Nanni L; Costa P; Moretta L
p40 molecule regulates NK cell activation mediated by NK receptors for HLA class I antigens and TCR-mediated triggering of T lymphocytes.
International immunology 1997;9(9):1271-9.
1997: De Maria A; Ferraris A; Guastella M; Pilia S; Cantoni C; Polero L; Mingari M C; Bassetti D; Fauci A S; Moretta L
Expression of HLA class I-specific inhibitory natural killer cell receptors in HIV-specific cytolytic T lymphocytes: impairment of specific cytolytic functions.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(19):10285-8.
1997: Mingari M C; Ponte M; Vitale C; Schiavetti F; Bertone S; Moretta L
Expression of HLA class I-specific inhibitory receptors by chronically activated cytolytic T lymphocytes: useful or harmful to the host?
Melanoma research 1997;7 Suppl 2():S89-93.
1997: Pende D; Sivori S; Accame L; Pareti L; Falco M; Geraghty D; Le Bouteiller P; Moretta L; Moretta A
HLA-G recognition by human natural killer cells. Involvement of CD94 both as inhibitory and as activating receptor complex.
European journal of immunology 1997;27(8):1875-80.
1997: Poggi A; Costa P; Zocchi M R; Moretta L
NKRP1A molecule is involved in transendothelial migration of CD4+ human T lymphocytes.
Immunology letters 1997;57(1-3):121-3.
1997: Mingari M C; Vitale C; Cantoni C; Bellomo R; Ponte M; Schiavetti F; Bertone S; Moretta A; Moretta L
Interleukin-15-induced maturation of human natural killer cells from early thymic precursors: selective expression of CD94/NKG2-A as the only HLA class I-specific inhibitory receptor.
European journal of immunology 1997;27(6):1374-80.
1997: Moretta A; Biassoni R; Bottino C; Pende D; Vitale M; Poggi A; Mingari M C; Moretta L
Major histocompatibility complex class I-specific receptors on human natural killer and T lymphocytes.
Immunological reviews 1997;155():105-17.
1997: Mingari M C; Ponte M; Vitale C; Schiavetti F; Bertone S; Moretta L
Inhibitory receptors for HLA class I molecules on cytolytic T lymphocytes. Functional relevance and implications for anti-tumor immune responses.
International journal of clinical & laboratory research 1997;27(2):87-94.
1996: Poggi A; Pella N; Cantoni C; Zocchi M R; Moretta L
Physical and functional association of CD45 and CD3-TCR complex on CD1+ human thymocytes. Evidence that the engagement of CD45 molecules can prevent CD1+ thymocytes from apoptosis.
International immunology 1996;8(12):1947-53.
1996: Mingari M C; Schiavetti F; Ponte M; Vitale C; Maggi E; Romagnani S; Demarest J; Pantaleo G; Fauci A S; Moretta L
Human CD8+ T lymphocyte subsets that express HLA class I-specific inhibitory receptors represent oligoclonally or monoclonally expanded cell populations.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(22):12433-8.
1996: Sivori S; Vitale M; Bottino C; Marcenaro E; Sanseverino L; Parolini S; Moretta L; Moretta A
CD94 functions as a natural killer cell inhibitory receptor for different HLA class I alleles: identification of the inhibitory form of CD94 by the use of novel monoclonal antibodies.
European journal of immunology 1996;26(10):2487-92.
1996: Bottino C; Sivori S; Vitale M; Cantoni C; Falco M; Pende D; Morelli L; Augugliaro R; Semenzato G; Biassoni R; Moretta L; Moretta A
A novel surface molecule homologous to the p58/p50 family of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation.
European journal of immunology 1996;26(8):1816-24.
1996: Pende D; Biassoni R; Cantoni C; Verdiani S; Falco M; di Donato C; Accame L; Bottino C; Moretta A; Moretta L
The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer.
The Journal of experimental medicine 1996;184(2):505-18.
1996: Olcese L; Lang P; Vély F; Cambiaggi A; Marguet D; Bléry M; Hippen K L; Biassoni R; Moretta A; Moretta L; Cambier J C; Vivier E
Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(12):4531-4.
1996: Poggi A; Costa P; Morelli L; Cantoni C; Pella N; Spada F; Biassoni R; Nanni L; Revello V; Tomasello E; Mingari M C; Moretta A; Moretta L
Expression of human NKRP1A by CD34+ immature thymocytes: NKRP1A-mediated regulation of proliferation and cytolytic activity.
European journal of immunology 1996;26(6):1266-72.
1996: Poggi A; Spada F; Costa P; Tomasello E; Revello V; Pella N; Zocchi M R; Moretta L
Dissection of lymphocyte function-associated antigen 1-dependent adhesion and signal transduction in human natural killer cells shown by the use of cholera or pertussis toxin.
European journal of immunology 1996;26(5):967-75.
1996: Mingari M C; Maggi E; Cambiaggi A; Annunziato F; Schiavetti F; Manetti R; Moretta L; Romagnani S
Development in vitro of human CD4+ thymocytes into functionally mature Th2 cells. Exogenous interleukin-12 is required for priming thymocytes to produce both Th1 cytokines and interleukin-10.
European journal of immunology 1996;26(5):1083-7.
1996: Cambiaggi A; Orengo A M; Meazza R; Sforzini S; Tazzari P L; Lauria F; Raspadori D; Zambello R; Semenzato G; Moretta L; Ferrini S
The natural killer-related receptor for HLA-C expressed on T cells from CD3+ lymphoproliferative disease of granular lymphocytes displays either inhibitory or stimulatory function.
Blood 1996;87(6):2369-75.
1996: Vitale M; Sivori S; Pende D; Augugliaro R; Di Donato C; Amoroso A; Malnati M; Bottino C; Moretta L; Moretta A
Physical and functional independency of p70 and p58 natural killer (NK) cell receptors for HLA class I: their role in the definition of different groups of alloreactive NK cell clones.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(4):1453-7.
1996: Biassoni R; Cantoni C; Falco M; Verdiani S; Bottino C; Vitale M; Conte R; Poggi A; Moretta A; Moretta L
The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions.
The Journal of experimental medicine 1996;183(2):645-50.
1995: Moretta A; Sivori S; Vitale M; Pende D; Morelli L; Augugliaro R; Bottino C; Moretta L
Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells.
The Journal of experimental medicine 1995;182(3):875-84.
1995: Biassoni R; Falco M; Cambiaggi A; Costa P; Verdiani S; Pende D; Conte R; Di Donato C; Parham P; Moretta L
Amino acid substitutions can influence the natural killer (NK)-mediated recognition of HLA-C molecules. Role of serine-77 and lysine-80 in the target cell protection from lysis mediated by "group 2" or "group 1" NK clones.
The Journal of experimental medicine 1995;182(2):605-9.
1995: Wagtmann N; Biassoni R; Cantoni C; Verdiani S; Malnati M S; Vitale M; Bottino C; Moretta L; Moretta A; Long E O
Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains.
Immunity 1995;2(5):439-49.
1995: Vitale M; Sivori S; Pende D; Moretta L; Moretta A
Coexpression of two functionally independent p58 inhibitory receptors in human natural killer cell clones results in the inability to kill all normal allogeneic target cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(8):3536-40.
1995: Ciccone E; Pende D; Nanni L; Di Donato C; Viale O; Beretta A; Vitale M; Sivori S; Moretta A; Moretta L
General role of HLA class I molecules in the protection of target cells from lysis by natural killer cells: evidence that the free heavy chains of class I molecules are not sufficient to mediate the protective effect.
International immunology 1995;7(3):393-400.
1995: Poggi A; Pella N; Morelli L; Spada F; Revello V; Sivori S; Augugliaro R; Moretta L; Moretta A
p40, a novel surface molecule involved in the regulation of the non-major histocompatibility complex-restricted cytolytic activity in humans.
European journal of immunology 1995;25(2):369-76.
1994: De Maria A; Cirillo C; Moretta L
Occurrence of human immunodeficiency virus type 1 (HIV-1)-specific cytolytic T cell activity in apparently uninfected children born to HIV-1-infected mothers.
The Journal of infectious diseases 1994;170(5):1296-9.
1994: Ferrini S; Cambiaggi A; Meazza R; Sforzini S; Marciano S; Mingari M C; Moretta L
T cell clones expressing the natural killer cell-related p58 receptor molecule display heterogeneity in phenotypic properties and p58 function.
European journal of immunology 1994;24(10):2294-8.
1994: Bottino C; Vitale M; Olcese L; Sivori S; Morelli L; Augugliaro R; Ciccone E; Moretta L; Moretta A
The human natural killer cell receptor for major histocompatibility complex class I molecules. Surface modulation of p58 molecules and their linkage to CD3 zeta chain, Fc epsilon RI gamma chain and the p56lck kinase.
European journal of immunology 1994;24(10):2527-34.
1994: Poggi A; Demarest J F; Costa P; Biassoni R; Pella N; Pantaleo G; Mingari M C; Moretta L
Expression of a wide T cell receptor V beta repertoire in human T lymphocytes derived in vitro from embryonic liver cell precursors.
European journal of immunology 1994;24(9):2258-61.
1994: Moretta A; Vitale M; Sivori S; Bottino C; Morelli L; Augugliaro R; Barbaresi M; Pende D; Ciccone E; Lopez-Botet M; Moretta L
Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles.
The Journal of experimental medicine 1994;180(2):545-55.
1994: Moretta L; Ciccone E; Poggi A; Mingari M C; Moretta A
Ontogeny, specific functions and receptors of human natural killer cells.
Immunology letters 1994;40(2):83-8.
1994: De Maria A; Colombini S; Schnittman S M; Moretta L
CD8+ cytolytic T lymphocytes become infected in vitro in the process of killing HIV-1-infected target cells.
European journal of immunology 1994;24(3):531-6.
1994: Ferrini S; Sforzini S; Cambiaggi A; Poggi A; Meazza R; Canevari S; Colnaghi M I; Moretta L
The LFA-1/ICAM cell adhesion pathway is involved in tumor-cell lysis mediated by bispecific monoclonal-antibody-targeted T lymphocytes.
International journal of cancer. Journal international du cancer 1994;56(6):846-52.
1994: Moretta L; Ciccone E; Mingari M C; Biassoni R; Moretta A
Human natural killer cells: origin, clonality, specificity, and receptors.
Advances in immunology 1994;55():341-80.
1993: Ferrini S; Cambiaggi A; Sforzini S; Marciano S; Canevari S; Mezzanzanica D; Colnaghi M I; Grossi C E; Moretta L
Targeting of T lymphocytes against EGF-receptor+ tumor cells by bispecific monoclonal antibodies: requirement of CD3 molecule cross-linking for T-cell activation.
International journal of cancer. Journal international du cancer 1993;55(6):931-7.
1993: Poggi A; Pardi R; Pella N; Morelli L; Sivori S; Vitale M; Revello V; Moretta A; Moretta L
CD45-mediated regulation of LFA1 function in human natural killer cells. Anti-CD45 monoclonal antibodies inhibit the calcium mobilization induced via LFA1 molecules.
European journal of immunology 1993;23(10):2454-63.
1993: Malnati M S; Lusso P; Ciccone E; Moretta A; Moretta L; Long E O
Recognition of virus-infected cells by natural killer cell clones is controlled by polymorphic target cell elements.
The Journal of experimental medicine 1993;178(3):961-9.
1993: Moretta A; Vitale M; Bottino C; Orengo A M; Morelli L; Augugliaro R; Barbaresi M; Ciccone E; Moretta L
P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities.
The Journal of experimental medicine 1993;178(2):597-604.
1993: Biassoni R; Verdiani S; Cambiaggi A; Romeo P H; Ferrini S; Moretta L
Human CD3-CD16+ natural killer cells express the hGATA-3 T cell transcription factor and an unrearranged 2.3-kb TcR delta transcript.
European journal of immunology 1993;23(5):1083-7.
1993: Ferrini S; Cambiaggi A; Sforzini S; Canevari S; Mezzanzanica D; Colnaghi M I; Moretta L
Use of anti-CD3 and anti-CD16 bispecific monoclonal antibodies for the targeting of T and NK cells against tumor cells.
Cancer detection and prevention 1993;17(2):295-300.
1992: Moretta L; Ciccone E; Pende D; Viale O; Di Donato C; Tripodi G; Orengo A M; Guardiola J; Moretta A
Existence of a natural killer (NK) cell repertoire for (allo)antigen recognition: definition of five distinct NK-determined allospecificities in humans.
Pharmacological research : the official journal of the Italian Pharmacological Society 1992;26 Suppl 2():98-9.
1992: Ferrini S; Cantoni C; Cambiaggi A; Chen Q; Venzano P; Canevari S; Colnaghi M I; Moretta L
Induction of anti-tumor immune response by bispecific monoclonal antibodies (bimAbs).
Pharmacological research : the official journal of the Italian Pharmacological Society 1992;26 Suppl 2():146-7.
1992: De Maria A; Ferrazin A; Ferrini S; Ciccone E; Terragna A; Moretta L
Selective increase of a subset of T cell receptor gamma delta T lymphocytes in the peripheral blood of patients with human immunodeficiency virus type 1 infection.
The Journal of infectious diseases 1992;165(5):917-9.
1992: Ciccone E; Pende D; Viale O; Di Donato C; Tripodi G; Orengo A M; Guardiola J; Moretta A; Moretta L
Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition: definition of five distinct NK-determined allospecificities in humans.
The Journal of experimental medicine 1992;175(3):709-18.
1992: Ciccone E; Moretta A; Moretta L
Specific functions of human NK cells.
Immunology letters 1992;31(2):99-103.
1992: Moretta L; Ciccone E; Pende D; Tripodi G; Bottino C; Moretta A
Human natural killer cells: clonally distributed specific functions and triggering surface molecules.
Laboratory investigation; a journal of technical methods and pathology 1992;66(2):138-42.
1992: Ferrini S; Cambiaggi A; Cantoni C; Canevari S; Mezzanzanica D; Colnaghi M I; Moretta L
Targeting of T or NK lymphocytes against tumor cells by bispecific monoclonal antibodies: role of different triggering molecules.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1992;7():15-8.
1992: Grossi C E; Ciccone E; Zeromski J; Moretta A; Moretta L
Functional and morphologic characterization of human T lymphocytes expressing the TCR gamma/delta.
Biotherapy (Dordrecht, Netherlands) 1992;5(1):1-9.
1991: Moretta A; Poggi A; Pende D; Tripodi G; Orengo A M; Pella N; Augugliaro R; Bottino C; Ciccone E; Moretta L
CD69-mediated pathway of lymphocyte activation: anti-CD69 monoclonal antibodies trigger the cytolytic activity of different lymphoid effector cells with the exception of cytolytic T lymphocytes expressing T cell receptor alpha/beta.
The Journal of experimental medicine 1991;174(6):1393-8.
1991: Ferrini S; Cantoni C; Ciccone E; Biassoni R; Prigione I; Bottino C; Venzano P; Moretta L
A novel surface molecule expressed by long-term cultured T and natural killer cells is involved in cell activation.
European journal of immunology 1991;21(9):1981-7.
1991: Mingari M C; Poggi A; Biassoni R; Bellomo R; Ciccone E; Pella N; Morelli L; Verdiani S; Moretta A; Moretta L
In vitro proliferation and cloning of CD3- CD16+ cells from human thymocyte precursors.
The Journal of experimental medicine 1991;174(1):21-6.
1991: Fagioli M; Carè A; Ciccone E; Moretta L; Moretta A; Meccia E; Testa U; Falini B; Grignani F; Peschle C
Molecular heterogeneity of the 1.0-kb T beta transcript in natural killer and gamma/delta lymphocytes.
European journal of immunology 1991;21(6):1529-34.
1991: Ferrini S; Prigione I; Miotti S; Ciccone E; Cantoni C; Chen Q; Colnaghi M I; Moretta L
Bispecific monoclonal antibodies directed to CD16 and to a tumor-associated antigen induce target-cell lysis by resting NK cells and by a subset of NK clones.
International journal of cancer. Journal international du cancer 1991;48(2):227-33.
1991: Moretta L; Ciccone E; Ferrini S; Pelicci P G; Mingari M C; Zeromski J; Bottino C; Grossi C; Moretta A
Molecular and cellular analysis of human T lymphocytes expressing gamma delta T-cell receptor.
Immunological reviews 1991;120():117-35.
1991: Mingari M C; Poggi A; Bellomo R; Pella N; Moretta L
Thymic origin of some natural killer cells: clonal proliferation of human CD3-16+ cells from CD3-4-8- thymocyte precursors requires the presence of H9 leukemic cells.
International journal of clinical & laboratory research 1991;21(2):176-8.
1991: Ciccone E; Viale O; Pende D; Malnati M; Moretta A; Moretta L
Specificity of human T lymphocytes expressing a gamma/delta T cell antigen receptor. Recognition of a polymorphic determinant of HLA class I molecules by a gamma/delta+ clone.
Current topics in microbiology and immunology 1991;173():223-7.
1990: Poggi A; Biassoni R; Pella N; Paolieri F; Bellomo R; Bertolini A; Moretta L; Mingari M C
In vitro expansion of CD3/TCR- human thymocyte populations that selectively lack CD3 delta gene expression: a phenotypic and functional analysis.
The Journal of experimental medicine 1990;172(5):1409-18.
1990: Moretta A; Bottino C; Pende D; Tripodi G; Orengo A M; Millo R; Pelicci P G; Ciccone E; Moretta L
Human T lymphocytes expressing TCR gamma/delta.
Research in immunology 1990;141(7):630-5.
1990: De Maria A F; Malnati M S; Poggi A; Pende D; Cottafava F; Moretta L
Clonal analysis of joint fluid T lymphocytes in patients with juvenile rheumatoid arthritis.
The Journal of rheumatology 1990;17(8):1073-8.
1990: Fagioli M; Ciccone E; Bottino C; Falini B; Grignani F; Moretta A; Moretta L; Pelicci P G
The C gamma 1-encoded disulphide-linked and the C gamma 2-encoded nondisulphide-linked forms of the gamma/delta heterodimer use different gamma and delta variable regions.
Blood 1990;76(2):279-84.
1990: Ciccone E; Pende D; Viale O; Tambussi G; Ferrini S; Biassoni R; Longo A; Guardiola J; Moretta A; Moretta L
Specific recognition of human CD3-CD16+ natural killer cells requires the expression of an autosomic recessive gene on target cells.
The Journal of experimental medicine 1990;172(1):47-52.
1990: Poggi A; Maggi E; Biagiotti R; Giudizi M G; Almerigogna F; Pella N; Caligaris-Cappio F; Romagnani S; Moretta L
A novel pathway of human B cell activation initiated by CK226 surface antigen.
European journal of immunology 1990;20(5):1161-5.
1990: Carè A; Pelicci P G; Meccia E; Fagioli M; Testa U; Ciccone E; Moretta A; Moretta L; Peschle C
Natural killer cells carry the germ-line configuration of the T cell receptor delta chain gene and heterogeneously express six distinct delta transcripts.
European journal of immunology 1990;20(4):939-42.
1990: Velardi A; Varese P; Grossi C E; Albi N; Dembech C; Terenzi A; Moretta L; Grignani F; Martelli M F; Mingari M C
Cytolytic function of clonable T cells after human bone marrow transplantation.
Blood 1990;75(6):1364-9.
1990: Moretta A; Tambussi G; Bottino C; Tripodi G; Merli A; Ciccone E; Pantaleo G; Moretta L
A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function.
The Journal of experimental medicine 1990;171(3):695-714.
1990: Ciccone E; Grossi C E; Malorni W; Arancia G; Mingari M C; Ferrini S; Moretta A; Moretta L
Human lymphocytes expressing a TCR gamma/delta.
Annali dell'Istituto superiore di sanità 1990;26(3-4):349-56.
1990: Fagioli M; Carè A; Ciccone E; Moretta L; Moretta A; Testa U; Falini B; Grignani F; Peschle C; Pelicci P G
Molecular studies on LAK cells.
Annali dell'Istituto superiore di sanità 1990;26(3-4):357-68.
1989: Moretta A; Tambussi G; Ciccone E; Pende D; Melioli G; Moretta L
CD16 surface molecules regulate the cytolytic function of CD3CD16+ human natural killer cells.
International journal of cancer. Journal international du cancer 1989;44(4):727-30.
1989: Velardi A; Varese P; Terenzi A; Dembech C; Albi N; Grossi C E; Moretta L; Martelli M F; Grignani F; Mingari M C
Lymphokine production by T-cell clones after human bone marrow transplantation.
Blood 1989;74(5):1665-72.
1989: Falini B; Flenghi L; Pileri S; Pelicci P; Fagioli M; Martelli M F; Moretta L; Ciccone E
Distribution of T cells bearing different forms of the T cell receptor gamma/delta in normal and pathological human tissues.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(8):2480-8.
1989: Moretta L; Ciccone E; Mingari M C; Zeromski J; Bottino C; Ferrini S; Tambussi G; Melioli G; Grossi C E; Moretta A
Phenotypic and functional characterization of human T lymphocytes expressing a gamma/delta T cell antigen receptor.
Clinical and experimental rheumatology 1989;7 Suppl 3():S9-14.
1989: Ferrini S; Prigione I; Mammoliti S; Colnaghi M I; Ménard S; Moretta A; Moretta L
Re-targeting of human lymphocytes expressing the T-cell receptor gamma/delta to ovarian carcinoma cells by the use of bispecific monoclonal antibodies.
International journal of cancer. Journal international du cancer 1989;44(2):245-50.
1989: Ciccone E; Viale O; Pende D; Malnati M; Battista Ferrara G; Barocci S; Moretta A; Moretta L
Specificity of human T lymphocytes expressing a gamma/delta T cell antigen receptor. Recognition of a polymorphic determinant of HLA class I molecules by a gamma/delta clone.
European journal of immunology 1989;19(7):1267-71.
1989: Ferrini S; Prigione I; Bottino C; Ciccone E; Tambussi G; Mammoliti S; Moretta L; Moretta A
Monoclonal antibodies which react with the T cell receptor gamma/delta recognize different subsets of CD3+WT31- T lymphocytes.
European journal of immunology 1989;19(1):57-61.
1989: Moretta L; Ciccone E; Mingari M C; Bottino C; Ferrini S; Tambussi G; Melioli G; Grossi C E; Moretta A
Human T lymphocytes expressing gamma/delta T cell antigen receptor.
Clinical immunology and immunopathology 1989;50(1 Pt 2):S117-23.
1989: Melioli G; Ciccone E; Mingari M C; Pende D; Viale O; Tambussi G; Merli A; Moretta A; Moretta L
Specific recognition by CD3- NK cells: a limiting dilution analysis of the frequency of alloreactive CD3- lymphocyte precursors.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1989;4():56-7.
1989: Ferrini S; Prigione I; Mammoliti S; Colnaghi M I; Menard S; Moretta A; Moretta L
Retargeting of T-cell-receptor gamma/delta+ lymphocytes against tumor cells by bispecific monoclonal antibodies. Induction of cytolytic activity and lymphokine production.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1989;4():53-5.
1989: Mingari M C; Varese P; Bottino C; Tambussi G; Moretta L
Human thymocytes expressing gamma/delta T-cell receptors.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1989;4():39-42.
1988: Ciccone E; Viale O; Pende D; Malnati M; Biassoni R; Melioli G; Moretta A; Long E O; Moretta L
Specific lysis of allogeneic cells after activation of CD3- lymphocytes in mixed lymphocyte culture.
The Journal of experimental medicine 1988;168(6):2403-8.
1988: Mingari M C; Varese P; Bottino C; Melioli G; Moretta A; Moretta L
Clonal analysis of CD4-CD8- human thymocytes expressing a T cell receptor gamma/delta chain. Direct evidence for the de novo expression of CD8 surface antigen and of cytolytic activity against tumor targets.
European journal of immunology 1988;18(11):1831-4.
1988: Bottino C; Tambussi G; Ferrini S; Ciccone E; Varese P; Mingari M C; Moretta L; Moretta A
Two subsets of human T lymphocytes expressing gamma/delta antigen receptor are identifiable by monoclonal antibodies directed to two distinct molecular forms of the receptor.
The Journal of experimental medicine 1988;168(2):491-505.
1988: Ciccone E; Ferrini S; Bottino C; Viale O; Prigione I; Pantaleo G; Tambussi G; Moretta A; Moretta L
A monoclonal antibody specific for a common determinant of the human T cell receptor gamma/delta directly activates CD3+WT31- lymphocytes to express their functional program(s).
The Journal of experimental medicine 1988;168(1):1-11.
1988: Ciccone E; Viale O; Bottino C; Pende D; Migone N; Casorati G; Tambussi G; Moretta A; Moretta L
Antigen recognition by human T cell receptor gamma-positive lymphocytes. Specific lysis of allogeneic cells after activation in mixed lymphocyte culture.
The Journal of experimental medicine 1988;167(4):1517-22.
1988: Melioli G; Baldini E; De Maria A; Moretta L
Intraperitoneal infusion of interleukin-2 in patients with malignant ascites: phenotypic and functional effects on tumor-associated lymphocytes.
La Ricerca in clinica e in laboratorio 1988;18(1):61-6.
1988: Mingari M C; Varese P; Bottino C; Merli A; Moretta L
Interleukin-2-induced proliferation of CD4-CD8- human thymocytes. In vitro expression of CD3 and CD8 antigens and cytolytic activity.
La Ricerca in clinica e in laboratorio 1988;18(1):67-73.
1987: Mingari M C; Ferrini S; Pende D; Bottino C; Prigione I; Moretta A; Moretta L
Phenotypic and functional analysis of human CD3+ and CD3- clones with "lymphokine-activated killer" (LAK) activity. Frequent occurrence of CD3+ LAK clones which produce interleukin-2.
International journal of cancer. Journal international du cancer 1987;40(4):495-8.
1987: Moretta L; Pende D; Bottino C; Migone N; Ciccone E; Ferrini S; Mingari M C; Moretta A
Human CD3+4-8-WT31- T lymphocyte populations expressing the putative T cell receptor gamma-gene product. A limiting dilution and clonal analysis.
European journal of immunology 1987;17(9):1229-34.
1987: Bottino C; Ferrini S; Ciccone E; Prigione I; Pende D; Mingari M C; Moretta L; Moretta A
Analysis of CD3-associated molecules in CD4- 8- human T cell clones lacking the typical alpha/beta T cell receptor.
La Ricerca in clinica e in laboratorio 1987;17(2):125-9.
1986: Moretta L; Pende D; Cozzani R; Merli A; Bagnasco M; Mingari M C
T cell nature of some lymphokine-activated killer (LAK) cells. Frequency analysis of LAK precursors within human T cell populations and clonal analysis of LAK effector cells.
European journal of immunology 1986;16(12):1623-5.
1986: Mingari M C; Pende D; Cozzani R; Merli A; Poggi A; Ferrini S; Moretta L
Both the precursors and the effectors of human lymphokine-activated killer (LAK) cells may belong to T lymphocytes.
La Ricerca in clinica e in laboratorio 1986;16(3):437-41.
1986: Mingari M C; Gerosa F; Maggi E; Cozzani R; Pende D; Bottino C; Poggi A; Romagnani S; Moretta L
Heterogeneity of B cell growth factor (BCGF)-producing T cells in humans. Clonal analysis of BCGF-producing cells within T4+ and T8+ subsets and evidence for the involvement of different growth factors in different BCGF assays.
La Ricerca in clinica e in laboratorio 1986;16(1):23-8.
1985: Melioli G; Merli A; Ferrini S; Mingari M C; Moretta L
Phenotypic and functional heterogeneity of human T cell clones producing gamma-interferon.
La Ricerca in clinica e in laboratorio 1985;15(1):47-52.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Lorenzo Moretta

Research Profile (preview)

Anatomy

Chemicals & Drugs

Physiology

Living Beings

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Lorenzo Moretta (preview)

All Publications