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Paul Moretti

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Chemicals & Drugs

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Amino Acid Sequences

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Publications

TOP 3
Jeffrey M Barrett; Sarah L Brice; Michaelia P Cockshell; Paul A B Moretti; Kate A Parham; Jyotsna B Pippal; Stuart M Pitson; Claudine S Bonder
Over-expression of sphingosine kinase-1 enhances a progenitor phenotype in human endothelial cells.
Melissa R Pitman; Renae K Barr; Briony L Gliddon; Angus M Magarey; Paul A B Moretti; Stuart M Pitson
A critical role for the protein phosphatase 2A B'α regulatory subunit in dephosphorylation of sphingosine kinase 1.
Kate E Jarman; Paul A B Moretti; Julia R Zebol; Stuart M Pitson
Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1.

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All Publications

2011: Jeffrey M Barrett; Sarah L Brice; Michaelia P Cockshell; Paul A B Moretti; Kate A Parham; Jyotsna B Pippal; Stuart M Pitson; Claudine S Bonder
Over-expression of sphingosine kinase-1 enhances a progenitor phenotype in human endothelial cells.
Microcirculation (New York, N.Y. : 1994) 2011;18(7):583-97.
2011: Melissa R Pitman; Renae K Barr; Briony L Gliddon; Angus M Magarey; Paul A B Moretti; Stuart M Pitson
A critical role for the protein phosphatase 2A B'α regulatory subunit in dephosphorylation of sphingosine kinase 1.
The international journal of biochemistry & cell biology 2011;43(3):342-7.
2010: Kate E Jarman; Paul A B Moretti; Julia R Zebol; Stuart M Pitson
Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1.
The Journal of biological chemistry 2010;285(1):483-92.
2009: Julia R Zebol; Niamh M Hewitt; Paul A B Moretti; Helen E Lynn; Julie A Lake; Peng Li; Mathew A Vadas; Binks W Wattenberg; Stuart M Pitson
The CCT/TRiC chaperonin is required for maturation of sphingosine kinase 1.
The international journal of biochemistry & cell biology 2009;41(4):822-7.
2008: Renae K Barr; Helen E Lynn; Paul A B Moretti; Yeesim Khew-Goodall; Stuart M Pitson
Deactivation of sphingosine kinase 1 by protein phosphatase 2A.
The Journal of biological chemistry 2008;283(50):34994-5002.
2008: Tamara M Leclercq; Paul A B Moretti; Mathew A Vadas; Stuart M Pitson
Eukaryotic elongation factor 1A interacts with sphingosine kinase and directly enhances its catalytic activity.
The Journal of biological chemistry 2008;283(15):9606-14.
2006: Catherine M Sutherland; Paul A B Moretti; Niamh M Hewitt; Christopher J Bagley; Mathew A Vadas; Stuart M Pitson
The calmodulin-binding site of sphingosine kinase and its role in agonist-dependent translocation of sphingosine kinase 1 to the plasma membrane.
The Journal of biological chemistry 2006;281(17):11693-701.
2005: Stuart M Pitson; Pu Xia; Tamara M Leclercq; Paul A B Moretti; Julia R Zebol; Helen E Lynn; Binks W Wattenberg; Mathew A Vadas
Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling.
The Journal of experimental medicine 2005;201(1):49-54.
2004: Jane L Roberts; Paul A B Moretti; Andrew L Darrow; Claudia K Derian; Mathew A Vadas; Stuart M Pitson
An assay for sphingosine kinase activity using biotinylated sphingosine and streptavidin-coated membranes.
Analytical biochemistry 2004;331(1):122-9.
2003: Stuart M Pitson; Paul A B Moretti; Julia R Zebol; Helen E Lynn; Pu Xia; Mathew A Vadas; Binks W Wattenberg
Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation.
The EMBO journal 2003;22(20):5491-500.
2002: Stuart M Pitson; Paul A B Moretti; Julia R Zebol; Reza Zareie; Claudia K Derian; Andrew L Darrow; Jenson Qi; Richard J D'Andrea; Christopher J Bagley; Mathew A Vadas; Binks W Wattenberg
The nucleotide-binding site of human sphingosine kinase 1.
The Journal of biological chemistry 2002;277(51):49545-53.
2002: Pu Xia; Lijun Wang; Paul A B Moretti; Nathaniel Albanese; Fugui Chai; Stuart M Pitson; Richard J D'Andrea; Jennifer R Gamble; Mathew A Vadas
Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-alpha signaling.
The Journal of biological chemistry 2002;277(10):7996-8003.
2001: Stuart M Pitson; Paul A B Moretti; Julia R Zebol; Mathew A Vadas; Richard J D'Andrea; Binks W Wattenberg
A point mutant of human sphingosine kinase 1 with increased catalytic activity.
FEBS letters 2001;509(2):169-73.
2001: Paul A B Moretti; A J Davidson; E Baker; B Lilley; L I Zon; Richard J D'Andrea
Molecular cloning of a human Vent-like homeobox gene.
Genomics 2001;76(1-3):21-9.
2000: Pu Xia; Jennifer R Gamble; Lijun Wang; Stuart M Pitson; Paul A B Moretti; Binks W Wattenberg; Richard J D'Andrea; Mathew A Vadas
An oncogenic role of sphingosine kinase.
Current biology : CB 2000;10(23):1527-30.
2000: Stuart M Pitson; Paul A B Moretti; Julia R Zebol; Pu Xia; Jennifer R Gamble; Mathew A Vadas; Richard J D'Andrea; Binks W Wattenberg
Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation. A dominant-negative sphingosine kinase.
The Journal of biological chemistry 2000;275(43):33945-50.
2000: Stuart M Pitson; Richard J D'Andrea; L Vandeleur; Paul A B Moretti; Pu Xia; Jennifer R Gamble; Mathew A Vadas; Binks W Wattenberg
Human sphingosine kinase: purification, molecular cloning and characterization of the native and recombinant enzymes.
The Biochemical journal 2000;350 Pt 2():429-41.
1997: S C Barry; E Korpelainen; Q Sun; Frank C Stomski; Paul A B Moretti; H Wakao; Richard J D'Andrea; Mathew A Vadas; Angel F Lopez; Gregory J Goodall
Roles of the N and C terminal domains of the interleukin-3 receptor alpha chain in receptor function.
Blood 1997;89(3):842-52.