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David Beeler

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TOP 3
Roger Lawrence; Balagurunathan Kuberan; Miroslaw Lech; David L Beeler; Robert D Rosenberg
Mapping critical biological motifs and biosynthetic pathways of heparan sulfate.
Zhengliang L Wu; Miroslaw Lech; David L Beeler; Robert D Rosenberg
Determining heparan sulfate structure in the vicinity of specific sulfotransferase recognition sites by mass spectrometry.
Balagurunathan Kuberan; David L Beeler; Miroslaw Lech; Zhengliang L Wu; Robert D Rosenberg
Chemoenzymatic synthesis of classical and non-classical anticoagulant heparan sulfate polysaccharides.

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All Publications

2004: Roger Lawrence; Balagurunathan Kuberan; Miroslaw Lech; David L Beeler; Robert D Rosenberg
Mapping critical biological motifs and biosynthetic pathways of heparan sulfate.
Glycobiology 2004;14(5):467-79.
2004: Zhengliang L Wu; Miroslaw Lech; David L Beeler; Robert D Rosenberg
Determining heparan sulfate structure in the vicinity of specific sulfotransferase recognition sites by mass spectrometry.
The Journal of biological chemistry 2004;279(3):1861-6.
2003: Balagurunathan Kuberan; David L Beeler; Miroslaw Lech; Zhengliang L Wu; Robert D Rosenberg
Chemoenzymatic synthesis of classical and non-classical anticoagulant heparan sulfate polysaccharides.
The Journal of biological chemistry 2003;278(52):52613-21.
2003: Balagurunathan Kuberan; Miroslaw Lech; David L Beeler; Zhengliang L Wu; Robert D Rosenberg
Enzymatic synthesis of antithrombin III-binding heparan sulfate pentasaccharide.
Nature biotechnology 2003;21(11):1343-6.
2003: Balagurunathan Kuberan; David L Beeler; Roger Lawrence; Miroslaw Lech; Robert D Rosenberg
Rapid two-step synthesis of mitrin from heparosan: a replacement for heparin.
Journal of the American Chemical Society 2003;125(41):12424-5.
2003: Zhengliang L Wu; Lijuan Zhang; Tomio Yabe; Balagurunathan Kuberan; David L Beeler; Andre Love; Robert D Rosenberg
The involvement of heparan sulfate (HS) in FGF1/HS/FGFR1 signaling complex.
The Journal of biological chemistry 2003;278(19):17121-9.
2003: Sassan HajMohammadi; Keiichi Enjyoji; Marc Princivalle; Patricia Christi; Miroslaw Lech; David L Beeler; Helen Rayburn; John J Schwartz; Samad Barzegar; Ariane I de Agostini; Mark J Post; Robert D Rosenberg; Nicholas W Shworak
Normal levels of anticoagulant heparan sulfate are not essential for normal hemostasis.
The Journal of clinical investigation 2003;111(7):989-99.
2002: Balagurunathan Kuberan; Miroslaw Lech; Lijuan Zhang; Zhengliang L Wu; David L Beeler; Robert D Rosenberg
Analysis of heparan sulfate oligosaccharides with ion pair-reverse phase capillary high performance liquid chromatography-microelectrospray ionization time-of-flight mass spectrometry.
Journal of the American Chemical Society 2002;124(29):8707-18.
2002: Zhengliang L Wu; Lijuan Zhang; David L Beeler; Balagurunathan Kuberan; Robert D Rosenberg
A new strategy for defining critical functional groups on heparan sulfate.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(6):539-45.
2001: Lijuan Zhang; David L Beeler; Roger Lawrence; Miroslaw Lech; Jian Liu; J C Davis; Zachary Shriver; Ram Sasisekharan; R D Rosenberg
6-O-sulfotransferase-1 represents a critical enzyme in the anticoagulant heparan sulfate biosynthetic pathway.
The Journal of biological chemistry 2001;276(45):42311-21.
1999: Keiichi Enjyoji; Jean Sévigny; Y Lin; Paul S. Frenette; PD Christie; J S Esch; M Imai; Jay M Edelberg; Helen Rayburn; Miroslaw Lech; David L Beeler; Eva Csizmadia; Denisa D Wagner; Simon C Robson; R D Rosenberg
Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation.
Nature medicine 1999;5(9):1010-7.
1998: H Weiler-Guettler; PD Christie; David L Beeler; AM Healy; W W Hancock; Helen Rayburn; Jay M Edelberg; R D Rosenberg
A targeted point mutation in thrombomodulin generates viable mice with a prethrombotic state.
The Journal of clinical investigation 1998;101(9):1983-91.
1994: David J Kuter; David L Beeler; R D Rosenberg
The purification of megapoietin: a physiological regulator of megakaryocyte growth and platelet production.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):11104-8.
1993: K Ravid; David J Kuter; David L Beeler; T Doi; R D Rosenberg
Selection of an HEL-derived cell line expressing high levels of platelet factor 4.
Blood 1993;81(11):2885-90.
1992: K Yu; H Morioka; L M Fritze; David L Beeler; Robert Jackman; R D Rosenberg
Transcriptional regulation of the thrombomodulin gene.
The Journal of biological chemistry 1992;267(32):23237-47.
1991: K Ravid; T Doi; David L Beeler; David J Kuter; R D Rosenberg
Transcriptional regulation of the rat platelet factor 4 gene: interaction between an enhancer/silencer domain and the GATA site.
Molecular and cellular biology 1991;11(12):6116-27.
1991: K Ravid; David L Beeler; M S Rabin; H Earl Ruley; R D Rosenberg
Selective targeting of gene products with the megakaryocyte platelet factor 4 promoter.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(4):1521-5.
1987: Robert Jackman; David L Beeler; L Fritze; Gerald A Soff; R D Rosenberg
Human thrombomodulin gene is intron depleted: nucleic acid sequences of the cDNA and gene predict protein structure and suggest sites of regulatory control.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(18):6425-9.
1986: Robert Jackman; David L Beeler; L VanDeWater; R D Rosenberg
Characterization of a thrombomodulin cDNA reveals structural similarity to the low density lipoprotein receptor.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(23):8834-8.