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Matthias Mörgelin

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Magnus G Olsson; Lena W Rosenlöf; Vineta Fellman; H Kotarsky; Tomas Leanderson; Matthias Mörgelin; Tor Olofsson; Bo Akerström
The Radical-Binding Lipocalin A1M Binds to a Complex I Subunit and Protects Mitochondrial Structure and Function.
L I Påhlman; Artur Schmidtchen; G Kasetty; Matthias Mörgelin; A I Olin; Heiko Herwald
Antimicrobial activity of fibrinogen and fibrinogen-derived peptides - a novel link between coagulation and innate immunity.
Christopher Sjöwall; Thomas Skogh; Gunnar Sturfelt; Jonas Wetterö; Matthias Mörgelin; Ola Nived; Anders I Olin; Anders A Bengtsson
C-reactive protein, immunoglobulin G and complement co-localize in renal immune deposits of proliferative lupus nephritis.

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2013: Magnus G Olsson; Lena W Rosenlöf; Vineta Fellman; H Kotarsky; Tomas Leanderson; Matthias Mörgelin; Tor Olofsson; Bo Akerström
The Radical-Binding Lipocalin A1M Binds to a Complex I Subunit and Protects Mitochondrial Structure and Function.
Antioxidants & redox signaling 2013;18(16):2017-28.
2013: L I Påhlman; Artur Schmidtchen; G Kasetty; Matthias Mörgelin; A I Olin; Heiko Herwald
Antimicrobial activity of fibrinogen and fibrinogen-derived peptides - a novel link between coagulation and innate immunity.
Thrombosis and haemostasis 2013;109(5):930-9.
2013: Christopher Sjöwall; Thomas Skogh; Gunnar Sturfelt; Jonas Wetterö; Matthias Mörgelin; Ola Nived; Anders I Olin; Anders A Bengtsson
C-reactive protein, immunoglobulin G and complement co-localize in renal immune deposits of proliferative lupus nephritis.
Autoimmunity 2013;46(3):205-14.
2013: Paulina Kucharzewska; Matthias Mörgelin; Markus Ringnér; Katrin J Svensson; Johanna E Welch; Johan Bengzon; Erika Bourseau-Guilmain; Helena C Christianson; Erik Fredlund; Mattias Belting
Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(18):7312-7.
2013: Yu-Ching Su; Birendra Singh; Anna M Blom; Farshid Jalalvand; Matthias Mörgelin; Kristian Riesbeck
Haemophilus influenzae acquires vitronectin via the ubiquitous Protein F to subvert host innate immunity.
Molecular microbiology 2013;87(6):1245-66.
2013: Birendra Singh; Marjolein M Thunnissen; Tamim Al-Jubair; Matthias Mörgelin; Kristian Riesbeck
The unique structure of Haemophilus influenzae protein E reveals multiple binding sites for host factors.
Infection and immunity 2013;81(3):801-14.
2013: Farshid Jalalvand; Matthias Mörgelin; Marta Brant; Oskar Hallgren; Birendra Singh; Yu-Ching Su; Gunilla Westergren-Thorsson; Kristian Riesbeck
Haemophilus influenzae protein F mediates binding to laminin and human pulmonary epithelial cells.
The Journal of infectious diseases 2013;207(5):803-13.
2013: Viveka Schaar; Matthias Mörgelin; Magnus Paulsson; Kristian Riesbeck
Outer membrane vesicles shield Moraxella catarrhalis β-lactamase from neutralization by serum IgG.
The Journal of antimicrobial chemotherapy 2013;68(3):593-600.
2013: Awahan Rahman; Yulia Shakirova; Kristina E Andersson; Patrik Brundin; Mari Ekman; Jonas S Erjefält; Jia-Yi Li; Matthias Mörgelin; Karl Swärd
Late onset vascular dysfunction in the R6/1 model of Huntington's disease.
European journal of pharmacology 2013;698(1-3):345-53.
2013: Camilla Melin Fürst; Matthias Mörgelin; Kasper Vadstrup; Anders Aspberg; Dick Heinegård; Anna Blom
The C-type lectin of the aggrecan g3 domain activates complement.
PloS one 2013;8(4):e61407.
2013: Sara K Söbirk; Paul Bates; Arne Egesten; Matthias Mörgelin; Oonagh Shannon; Mattias Collin
Human chemokines as antimicrobial peptides with direct parasiticidal effect on Leishmania mexicana in vitro.
PloS one 2013;8(3):e58129.
2012: Pontus Nordenfelt; Sofia Waldemarson; Christofer Karlsson; Adam Linder; Johan Malmström; Matthias Mörgelin; Lars Björck
Antibody orientation at bacterial surfaces is related to invasive infection.
The Journal of experimental medicine 2012;209(13):2367-81.
2012: Teresia Hallström; Ralf Hoffmann; Anja Kunert; Matthias Mörgelin; Marina Raguse; Christine Skerka; Diana Barthel; Peter F Zipfel
Dihydrolipoamide dehydrogenase of Pseudomonas aeruginosa is a surface-exposed immune evasion protein that binds three members of the factor H family and plasminogen.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(10):4939-50.
2012: Mette Eliasson; Johan A Malmström; Matthias Mörgelin; Anders I Olin; Mikael Bodelsson; Mattias Collin; Arne Egesten
Characterization of released polypeptides during an interferon-γ-dependent antibacterial response in airway epithelial cells.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2012;32(11):524-33.
2012: Sara L Nordin; Andreas Sonesson; Martin Malmsten; Matthias Mörgelin; Arne Egesten
The epithelium-produced growth factor midkine has fungicidal properties.
The Journal of antimicrobial chemotherapy 2012;67(8):1927-36.
2012: Kristofer Wollein Waldetoft; Lars Björck; Matthias Mörgelin; D Patric Nitsche-Schmitz; Anders I Olin; Lisbeth Svensson; Inga-Maria Frick
Streptococcal surface proteins activate the contact system and control its antibacterial activity.
The Journal of biological chemistry 2012;287(30):25010-8.
2012: Mari Ekman; Matthias Mörgelin; Catarina Rippe; Mardjaneh Karbalaei Sadegh; Saeed Dabestani; Bengt Uvelius; Karl Swärd
Association of muscarinic M₃ receptors and Kir6.1 with caveolae in human detrusor muscle.
European journal of pharmacology 2012;683(1-3):238-45.
2012: J Grommes; Tilman M Hackeng; Michael Jacobs; Rory R Koenen; Wolfgang M Kuebler; Philipp Markart; Matthias Mörgelin; Klaus T Preissner; Philipp von Hundelshausen; Sarawuth Wantha; Christian Weber; Malgorzata Wygrecka; Jean-Eric Alard; Maik Drechsler; Oliver Soehnlein
Disruption of platelet-derived chemokine heteromers prevents neutrophil extravasation in acute lung injury.
American journal of respiratory and critical care medicine 2012;185(6):628-36.
2012: Praveen Papareddy; Artur Schmidtchen; Björn Walse; Matthias Mörgelin; Martin Malmsten
Antimicrobial activity of peptides derived from human ß-amyloid precursor protein.
Journal of peptide science : an official publication of the European Peptide Society 2012;18(3):183-91.
2012: Jitka Petrlova; Linda M Roberts; Matthias Mörgelin; Annika Axelsson; Megan C Cochran; Trang Duong; Jens O Lagerstedt
The fibrillogenic L178H variant of apolipoprotein A-I forms helical fibrils.
Journal of lipid research 2012;53(3):390-8.
2012: Praveen Papareddy; Ole E Sørensen; Martina Kalle; Katarina Lundqvist; Martin Malmsten; Matthias Mörgelin; Artur Schmidtchen
Tissue factor pathway inhibitor 2 is found in skin and its C-terminal region encodes for antibacterial activity.
PloS one 2012;7(12):e52772.
2012: Martina Kalle; Gopinath Kasetty; Martin Malmsten; Matthias Mörgelin; Praveen Papareddy; Victoria Rydengård; Barbara Albiger; Mariena J A van der Plas; Artur Schmidtchen
Host defense peptides of thrombin modulate inflammation and coagulation in endotoxin-mediated shock and Pseudomonas aeruginosa sepsis.
PloS one 2012;7(12):e51313.
2012: J Grommes; Helene Hartwig; Michael Jacobs; Thomas Andreas Koeppel; Matthias Mörgelin; Marcel Binnebösel; Rolf Dembinski; Maik Drechsler; Santosh Vijayan; Christian Weber; Oliver Soehnlein
Simvastatin reduces endotoxin-induced acute lung injury by decreasing neutrophil recruitment and radical formation.
PloS one 2012;7(6):e38917.
2012: Anneli M L Edström Hägerwall; Per Fernlund; Birthe Kragelund; Martin Malmsten; Matthias Mörgelin; Victoria Rydengård; Maria Baumgarten; Alexander M Cole; Ole E Sørensen
β-Microseminoprotein endows post coital seminal plasma with potent candidacidal activity by a calcium- and pH-dependent mechanism.
PLoS pathogens 2012;8(4):e1002625.
2012: Suado M Abdillahi; Selma Balvanović; Maria Baumgarten; Matthias Mörgelin
Collagen VI encodes antimicrobial activity: novel innate host defense properties of the extracellular matrix.
Journal of innate immunity 2012;4(4):371-6.
2011: Andreas Sonesson; Ole E Sørensen; Gopinath Kasetty; Martin Malmsten; Matthias Mörgelin; Anders I Olin; Artur Schmidtchen
Thymic stromal lymphopoietin exerts antimicrobial activities.
Experimental dermatology 2011;20(12):1004-10.
2011: Inga-Maria Frick; Matthias Mörgelin; Sara L Nordin; Anders I Olin; Ole E Sørensen; Maria Baumgarten; Arne Egesten
Constitutive and inflammation-dependent antimicrobial peptides produced by epithelium are differentially processed and inactivated by the commensal Finegoldia magna and the pathogen Streptococcus pyogenes.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(8):4300-9.
2011: Teresia Hallström; Anna M Blom; Matthias Mörgelin; Fredrik Resman; Birendra Singh; Kristian Riesbeck
Haemophilus influenzae protein E binds to the extracellular matrix by concurrently interacting with laminin and vitronectin.
The Journal of infectious diseases 2011;204(7):1065-74.
2011: Torsten G Loof; Matthias Mörgelin; Anna Norrby-Teglund; Sonja Oehmcke; Anders I Olin; Ulrich Theopold; Gerhard Dickneite; Linda Johansson; Heiko Herwald
Coagulation, an ancestral serine protease cascade, exerts a novel function in early immune defense.
Blood 2011;118(9):2589-98.
2011: Katrin J Svensson; Johan Bengzon; Helena C Christianson; Maria C Johansson; Paulina Kucharzewska; Tobias Löfstedt; Matthias Mörgelin; Wolfram Ruf; Stefan Sköld; Mattias Belting
Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(32):13147-52.
2011: Birendra Singh; Peter Zipfel; Anna M Blom; Farshid Jalalvand; Matthias Mörgelin; Kristian Riesbeck
Haemophilus influenzae protein E recognizes the C-terminal domain of vitronectin and modulates the membrane attack complex.
Molecular microbiology 2011;81(1):80-98.
2011: Elizabeth C Murphy; Matthias Mörgelin; Jakki C Cooney; Inga-Maria Frick
Interaction of Bacteroides fragilis and Bacteroides thetaiotaomicron with the kallikrein-kinin system.
Microbiology (Reading, England) 2011;157(Pt 7):2094-105.
2011: Cetin Agar; Philip G de Groot; Bas de Laat; Heiko Herwald; Johannes Levels; Stephanie D D C Monk; Matthias Mörgelin; Rolf T Urbanus; Tom van der Poll; Gwendolyn van Os; Joost C M Meijers
β₂-glycoprotein I: a novel component of innate immunity.
Blood 2011;117(25):6939-47.
2011: Gopinath Kasetty; Praveen Papareddy; Martina Kalle; Victoria Rydengård; Matthias Mörgelin; Barbara Albiger; Martin Malmsten; Artur Schmidtchen
Structure-activity studies and therapeutic potential of host defense peptides of human thrombin.
Antimicrobial agents and chemotherapy 2011;55(6):2880-90.
2011: Viveka Schaar; Stefan P W de Vries; Maria Laura A Perez Vidakovics; Hester J Bootsma; Lennart Larsson; Peter W M Hermans; Anders Bjartell; Matthias Mörgelin; Kristian Riesbeck
Multicomponent Moraxella catarrhalis outer membrane vesicles induce an inflammatory response and are internalized by human epithelial cells.
Cellular microbiology 2011;13(3):432-49.
2011: Per Levéen; H Kotarsky; Matthias Mörgelin; Riitta Karikoski; Eskil Elmér; Vineta Fellman
The GRACILE mutation introduced into Bcs1l causes postnatal complex III deficiency: a viable mouse model for mitochondrial hepatopathy.
Hepatology (Baltimore, Md.) 2011;53(2):437-47.
2011: Arne Egesten; Inga-Maria Frick; Matthias Mörgelin; Anders I Olin; Lars Björck
Binding of albumin promotes bacterial survival at the epithelial surface.
The Journal of biological chemistry 2011;286(4):2469-76.
2011: Inga-Maria Frick; Oonagh Shannon; Per Åkesson; Matthias Mörgelin; Mattias Collin; Artur Schmidtchen; Lars Björck
Antibacterial activity of the contact and complement systems is blocked by SIC, a protein secreted by Streptococcus pyogenes.
The Journal of biological chemistry 2011;286(2):1331-40.
2011: Magnus G Olsson; Artur Schmidtchen; Ole E Sørensen; Maria Allhorn; Martin Cederlund; Jörgen Larsson; Katarina Lundqvist; Matthias Mörgelin; Bo Akerström
Up-regulation of A1M/α1-microglobulin in skin by heme and reactive oxygen species gives protection from oxidative damage.
PloS one 2011;6(11):e27505.
2011: Ramesh Tati; AnnCharlotte Kristoffersson; Minola Manea-Hedström; Peter Mathieson; Matthias Mörgelin; David Motto; Simon Satchell; Anne-Lie Ståhl; Diana Karpman
Phenotypic expression of ADAMTS13 in glomerular endothelial cells.
PloS one 2011;6(6):e21587.
2011: Marta Bober; Matthias Mörgelin; Anders I Olin; Ulrich von Pawel-Rammingen; Mattias Collin
The membrane bound LRR lipoprotein Slr, and the cell wall-anchored M1 protein from Streptococcus pyogenes both interact with type I collagen.
PloS one 2011;6(5):e20345.
2011: Gopinath Kasetty; Martin Malmsten; Matthias Mörgelin; Praveen Papareddy; Victoria Rydengård; Bo Svensson; Björn Walse; Martina Kalle; Artur Schmidtchen
The C-terminal sequence of several human serine proteases encodes host defense functions.
Journal of innate immunity 2011;3(5):471-82.
2010: Kaisa E Happonen; Tore Saxne; Anders Aspberg; Matthias Mörgelin; Dick Heinegård; Anna M Blom
Regulation of complement by cartilage oligomeric matrix protein allows for a novel molecular diagnostic principle in rheumatoid arthritis.
Arthritis and rheumatism 2010;62(12):3574-83.
2010: Oliver Soehnlein; Stefan Eriksson; Hans Hjelmqvist; Andreas Andersson; Matthias Mörgelin; Lennart Lindbom; Mats Rundgren; Robert Frithiof
Anesthesia aggravates lung damage and precipitates hypotension in endotoxemic sheep.
Shock (Augusta, Ga.) 2010;34(4):412-9.
2010: Oonagh Shannon; Matthias Mörgelin; Magnus Rasmussen
Platelet activation and biofilm formation by Aerococcus urinae, an endocarditis-causing pathogen.
Infection and immunity 2010;78(10):4268-75.
2010: Oonagh Shannon; Victoria Rydengård; Artur Schmidtchen; Matthias Mörgelin; Per Alm; Ole E Sørensen; Lars Björck
Histidine-rich glycoprotein promotes bacterial entrapment in clots and decreases mortality in a mouse model of sepsis.
Blood 2010;116(13):2365-72.
2010: Sonja Oehmcke; Oonagh Shannon; Matthias Mörgelin; Heiko Herwald
Streptococcal M proteins and their role as virulence determinants.
Clinica chimica acta; international journal of clinical chemistry 2010;411(17-18):1172-80.
2010: Praveen Papareddy; Martina Kalle; Gopinath Kasetty; Matthias Mörgelin; Victoria Rydengård; Barbara Albiger; Katarina Lundqvist; Martin Malmsten; Artur Schmidtchen
C-terminal peptides of tissue factor pathway inhibitor are novel host defense molecules.
The Journal of biological chemistry 2010;285(36):28387-98.
2010: Cetin Agar; Gwendolyn M A van Os; Matthias Mörgelin; Richard R Sprenger; J Arnoud Marquart; Rolf T Urbanus; R H W M Derksen; Joost C M Meijers; Philip G de Groot
Beta2-glycoprotein I can exist in 2 conformations: implications for our understanding of the antiphospholipid syndrome.
Blood 2010;116(8):1336-43.
2010: H Kotarsky; Riitta Karikoski; Matthias Mörgelin; Sanna Marjavaara; Petra Bergman; De-Liang Zhang; Joél Smet; Rudy Van Coster; Vineta Fellman
Characterization of complex III deficiency and liver dysfunction in GRACILE syndrome caused by a BCS1L mutation.
Mitochondrion 2010;10(5):497-509.
2010: Anders Wittrup; Si-He Zhang; Katrin J Svensson; Paulina Kucharzewska; Maria C Johansson; Matthias Mörgelin; Mattias Belting
Magnetic nanoparticle-based isolation of endocytic vesicles reveals a role of the heat shock protein GRP75 in macromolecular delivery.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(30):13342-7.
2010: Mette Eliasson; Matthias Mörgelin; Joshua M Farber; Arne Egesten; Barbara Albiger
Streptococcus pneumoniae induces expression of the antibacterial CXC chemokine MIG/CXCL9 via MyD88-dependent signaling in a murine model of airway infection.
Microbes and infection / Institut Pasteur 2010;12(7):565-73.
2010: Thorgerdur Sigurdardottir; Viveka Björck; Heiko Herwald; Matthias Mörgelin; Sigurbjörg Rutardottir; Johan Törnebrant; Mikael Bodelsson
M1 protein from streptococcus pyogenes induces nitric oxide-mediated vascular hyporesponsiveness to phenylephrine: involvement of toll-like receptor activation.
Shock (Augusta, Ga.) 2010;34(1):98-104.
2010: Sara L Svensson; mukesh pasupuleti; Björn Walse; Martin Malmsten; Matthias Mörgelin; Camilla Sjögren; Anders I Olin; Mattias Collin; Artur Schmidtchen; Ruth Palmer; Arne Egesten
Midkine and pleiotrophin have bactericidal properties: preserved antibacterial activity in a family of heparin-binding growth factors during evolution.
The Journal of biological chemistry 2010;285(21):16105-15.
2010: Adam Linder; Linda Johansson; Pontus Thulin; Erika Hertzén; Matthias Mörgelin; Bertil Christensson; Lars Björck; Anna Norrby-Teglund; Per Akesson
Erysipelas caused by group A streptococcus activates the contact system and induces the release of heparin-binding protein.
The Journal of investigative dermatology 2010;130(5):1365-72.
2010: Praveen Papareddy; Victoria Rydengård; mukesh pasupuleti; Björn Walse; Matthias Mörgelin; Anna Chalupka; Martin Malmsten; Artur Schmidtchen
Proteolysis of human thrombin generates novel host defense peptides.
PLoS pathogens 2010;6(4):e1000857.
2010: Magnus Rasmussen; Daniel Johansson; Sara K Söbirk; Matthias Mörgelin; Oonagh Shannon
Clinical isolates of Enterococcus faecalis aggregate human platelets.
Microbes and infection / Institut Pasteur 2010;12(4):295-301.
2010: Birendra Singh; Anna M Blom; Can Unal; Bo Nilson; Matthias Mörgelin; Kristian Riesbeck
Vitronectin binds to the head region of Moraxella catarrhalis ubiquitous surface protein A2 and confers complement-inhibitory activity.
Molecular microbiology 2010;75(6):1426-44.
2010: Jessica Petersson; Per Lönnbro; Anna-Maria Herr; Matthias Mörgelin; Urban Gullberg; Kristina Drott
The human IFN-inducible p53 target gene TRIM22 colocalizes with the centrosome independently of cell cycle phase.
Experimental cell research 2010;316(4):568-79.
2010: Zhi Wang; Christine Wilhelmsson; Pavel Hyrsl; Torsten G Loof; Pavel Dobes; Martina Klupp; Olga Loseva; Matthias Mörgelin; Jennifer Iklé; Richard M Cripps; Heiko Herwald; Ulrich Theopold
Pathogen entrapment by transglutaminase--a conserved early innate immune mechanism.
PLoS pathogens 2010;6(2):e1000763.
2010: Roland Schmitt; Fredric Carlsson; Matthias Mörgelin; Ramesh Tati; Gunnar Lindahl; Diana Karpman
Tissue deposits of IgA-binding streptococcal M proteins in IgA nephropathy and Henoch-Schonlein purpura.
The American journal of pathology 2010;176(2):608-18.
2010: Ladan Parhamifar; Wondossen Sime; Yuliana Yudina; Frederik Vilhardt; Matthias Mörgelin; Anita Sjölander
Ligand-induced tyrosine phosphorylation of cysteinyl leukotriene receptor 1 triggers internalization and signaling in intestinal epithelial cells.
PloS one 2010;5(12):e14439.
2010: Erika Hertzén; Linda Johansson; Robert Wallin; Heike Schmidt; Mirko Kroll; Anders P Rehn; Ramy Aziz; Matthias Mörgelin; Anna Norrby-Teglund
M1 protein-dependent intracellular trafficking promotes persistence and replication of Streptococcus pyogenes in macrophages.
Journal of innate immunity 2010;2(6):534-45.
2010: Christian Krintel; Cecilia Klint; Håkan Lindvall; Matthias Mörgelin; Cecilia Holm
Quarternary structure and enzymological properties of the different hormone-sensitive lipase (HSL) isoforms.
PloS one 2010;5(6):e11193.
2010: Marta Bober; Charlotte Enochsson; Mattias Collin; Matthias Mörgelin
Collagen VI is a subepithelial adhesive target for human respiratory tract pathogens.
Journal of innate immunity 2010;2(2):160-6.
2010: Maria Laura A Perez Vidakovics; Johan Jendholm; Matthias Mörgelin; Anne Månsson; Christer Larsson; Lars-Olaf Cardell; Kristian Riesbeck
B cell activation by outer membrane vesicles--a novel virulence mechanism.
PLoS pathogens 2010;6(1):e1000724.
2009: Erik Malmström; Matthias Mörgelin; Martin Malmsten; Linda Johansson; Anna Norrby-Teglund; Oonagh Shannon; Artur Schmidtchen; Joost C M Meijers; Heiko Herwald
Protein C inhibitor--a novel antimicrobial agent.
PLoS pathogens 2009;5(12):e1000698.
2009: Anders Wittrup; Si-He Zhang; Gerdy B ten Dam; Toin H van Kuppevelt; Per Bengtson; Maria Johansson; Johanna Welch; Matthias Mörgelin; Mattias Belting
ScFv antibody-induced translocation of cell-surface heparan sulfate proteoglycan to endocytic vesicles: evidence for heparan sulfate epitope specificity and role of both syndecan and glypican.
The Journal of biological chemistry 2009;284(47):32959-67.
2009: Christofer Karlsson; Mette Eliasson; Anders I Olin; Matthias Mörgelin; Anna Karlsson; Martin Malmsten; Arne Egesten; Inga-Maria Frick
SufA of the opportunistic pathogen finegoldia magna modulates actions of the antibacterial chemokine MIG/CXCL9, promoting bacterial survival during epithelial inflammation.
The Journal of biological chemistry 2009;284(43):29499-508.
2009: Dai-Qing Li; Xingjun Jing; Albert Salehi; Stephan C Collins; Michael B Hoppa; Anders H Rosengren; Enming Zhang; Ingmar Lundquist; Charlotta S Olofsson; Matthias Mörgelin; Lena Eliasson; Patrik Rorsman; Erik Renström
Suppression of sulfonylurea- and glucose-induced insulin secretion in vitro and in vivo in mice lacking the chloride transport protein ClC-3.
Cell metabolism 2009;10(4):309-15.
2009: Chantal J N Verkleij; Max Nieuwdorp; V E A Gerdes; Matthias Mörgelin; Joost C M Meijers; Pauline F Marx
The effects of hyperglycaemia on thrombin-activatable fibrinolysis inhibitor.
Thrombosis and haemostasis 2009;102(3):460-8.
2009: Christian Krintel; Matthias Mörgelin; Derek Logan; Cecilia Holm
Phosphorylation of hormone-sensitive lipase by protein kinase A in vitro promotes an increase in its hydrophobic surface area.
The FEBS journal 2009;276(17):4752-62.
2009: A Holmberg; R Lood; Matthias Mörgelin; B Söderquist; E Holst; Mattias Collin; B Christensson; Magnus Rasmussen
Biofilm formation by Propionibacterium acnes is a characteristic of invasive isolates.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2009;15(8):787-95.
2009: mukesh pasupuleti; Anna Chalupka; Matthias Mörgelin; Artur Schmidtchen; Martin Malmsten
Tryptophan end-tagging of antimicrobial peptides for increased potency against Pseudomonas aeruginosa.
Biochimica et biophysica acta 2009;1790(8):800-8.
2009: Sonja Oehmcke; Oonagh Shannon; Maren von Köckritz-Blickwede; Matthias Mörgelin; Adam Linder; Anders I Olin; Lars Björck; Heiko Herwald
Treatment of invasive streptococcal infection with a peptide derived from human high-molecular weight kininogen.
Blood 2009;114(2):444-51.
2009: Artur Schmidtchen; mukesh pasupuleti; Matthias Mörgelin; Mina Davoudi; Jan Alenfall; Anna Chalupka; Martin Malmsten
Boosting antimicrobial peptides by hydrophobic oligopeptide end tags.
The Journal of biological chemistry 2009;284(26):17584-94.
2009: Johan Jendholm; Matthias Mörgelin; Maria Laura A Perez Vidakovics; Michael Carlsson; Hakon Leffler; Lars-Olaf Cardell; Kristian Riesbeck
Superantigen- and TLR-dependent activation of tonsillar B cells after receptor-mediated endocytosis.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(8):4713-20.
2009: Elena Ronander; Marta Brant; Emily Eriksson; Matthias Mörgelin; Oskar Hallgren; Gunilla Westergren-Thorsson; Arne Forsgren; Kristian Riesbeck
Nontypeable Haemophilus influenzae adhesin protein E: characterization and biological activity.
The Journal of infectious diseases 2009;199(4):522-31.
2009: Kaisa E Happonen; Andreas P Sjöberg; Matthias Mörgelin; Dick Heinegård; Anna M Blom
Complement inhibitor C4b-binding protein interacts directly with small glycoproteins of the extracellular matrix.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(3):1518-25.
2009: Andreas P Sjöberg; Gavin A Manderson; Matthias Mörgelin; Anthony J Day; Dick Heinegård; Anna Blom
Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation.
Molecular immunology 2009;46(5):830-9.
2009: Sonja Oehmcke; Matthias Mörgelin; Heiko Herwald
Activation of the human contact system on neutrophil extracellular traps.
Journal of innate immunity 2009;1(3):225-30.
2009: Sara H Bengtson; Caroline Sandén; Matthias Mörgelin; Pauline F Marx; Anders I Olin; L M Fredrik Leeb-Lundberg; Joost C M Meijers; Heiko Herwald
Activation of TAFI on the surface of Streptococcus pyogenes evokes inflammatory reactions by modulating the kallikrein/kinin system.
Journal of innate immunity 2009;1(1):18-28.
2009: Arne Egesten; Anders I Olin; Helena M Linge; Manisha Yadav; Matthias Mörgelin; Anna Karlsson; Mattias Collin
SpeB of Streptococcus pyogenes differentially modulates antibacterial and receptor activating properties of human chemokines.
PloS one 2009;4(3):e4769.
2009: Katrin Dinkla; Susanne R Talay; Matthias Mörgelin; Rikki M A Graham; Manfred Rohde; D Patric Nitsche-Schmitz; Gursharan S Chhatwal
Crucial role of the CB3-region of collagen IV in PARF-induced acute rheumatic fever.
PloS one 2009;4(3):e4666.
2009: Christofer Karlsson; Matthias Mörgelin; Mattias Collin; Rolf Lood; Marie-Louise Andersson; Artur Schmidtchen; Lars Björck; Inga-Maria Frick
SufA - a bacterial enzyme that cleaves fibrinogen and blocks fibrin network formation.
Microbiology (Reading, England) 2009;155(Pt 1):238-48.
2008: Inga-Maria Frick; Christofer Karlsson; Matthias Mörgelin; Anders I Olin; Radmila Janjusevic; Clara Hammarström; Elisabet Holst; Maarten de Château; Lars Björck
Identification of a novel protein promoting the colonization and survival of Finegoldia magna, a bacterial commensal and opportunistic pathogen.
Molecular microbiology 2008;70(3):695-708.
2008: Sara H Bengtson; Jane Eddleston; Matthias Mörgelin; Bruce L Zuraw; Heiko Herwald
Regulation of kinin B(2) receptors by bradykinin in human lung cells.
Biological chemistry 2008;389(11):1435-40.
2008: Rishika A Pace; Rachel Peat; Naomi L Baker; Laura Zamurs; Matthias Mörgelin; Melita Irving; Naomi E Adams; John F Bateman; David Mowat; Nicholas J C Smith; Phillipa J Lamont; Steven A Moore; Katherine D Mathews; Kathryn N North; Shireen R Lamandé
Collagen VI glycine mutations: perturbed assembly and a spectrum of clinical severity.
Annals of neurology 2008;64(3):294-303.
2008: Anneli M L Edström; Johan Malm; Birgitta Frohm; Julie A Martellini; Aleksander Giwercman; Matthias Mörgelin; Alexander M Cole; Ole E Sørensen
The major bactericidal activity of human seminal plasma is zinc-dependent and derived from fragmentation of the semenogelins.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(5):3413-21.
2008: Victoria Rydengård; Oonagh Shannon; Katarina Lundqvist; Lukasz Kacprzyk; Anna Chalupka; Anna-Karin Olsson; Matthias Mörgelin; Willi Jahnen-Dechent; Martin Malmsten; Artur Schmidtchen
Histidine-rich glycoprotein protects from systemic Candida infection.
PLoS pathogens 2008;4(8):e1000116.
2008: Helena M Linge; Mattias Collin; Pontus Nordenfelt; Matthias Mörgelin; Martin Malmsten; Arne Egesten
The human CXC chemokine granulocyte chemotactic protein 2 (GCP-2)/CXCL6 possesses membrane-disrupting properties and is antibacterial.
Antimicrobial agents and chemotherapy 2008;52(7):2599-607.
2008: Teresia Hallström; Shirley A Müller; Matthias Mörgelin; Andrea Möllenkvist; Arne Forsgren; Kristian Riesbeck
The Moraxella IgD-binding protein MID/Hag is an oligomeric autotransporter.
Microbes and infection / Institut Pasteur 2008;10(4):374-81.
2008: Maria Nilsson; Sylwia Wasylik; Matthias Mörgelin; Anders I Olin; Joost C M Meijers; R H W M Derksen; Philip G de Groot; Heiko Herwald
The antibacterial activity of peptides derived from human beta-2 glycoprotein I is inhibited by protein H and M1 protein from Streptococcus pyogenes.
Molecular microbiology 2008;67(3):482-92.
2008: Alexei Navdaev; Vanessa Heitmann; Karla Desantana Evangelista; Matthias Mörgelin; Joachim Wegener; Johannes A Eble
The C-terminus of the gamma 2 chain but not of the beta 3 chain of laminin-332 is indirectly but indispensably necessary for integrin-mediated cell reactions.
Experimental cell research 2008;314(3):489-97.
2008: Lisa I Påhlman; Anders I Olin; Jessica Darenberg; Matthias Mörgelin; Malak Kotb; Heiko Herwald; Anna Norrby-Teglund
Soluble M1 protein of Streptococcus pyogenes triggers potent T cell activation.
Cellular microbiology 2008;10(2):404-14.
2008: Fredrik Kahn; Matthias Mörgelin; Oonagh Shannon; Anna Norrby-Teglund; Heiko Herwald; Anders I Olin; Lars Björck
Antibodies against a surface protein of Streptococcus pyogenes promote a pathological inflammatory response.
PLoS pathogens 2008;4(9):e1000149.
2008: Rolf Lood; Matthias Mörgelin; Anna Holmberg; Magnus Rasmussen; Mattias Collin
Inducible Siphoviruses in superficial and deep tissue isolates of Propionibacterium acnes.
BMC microbiology 2008;8():139.
2007: Lukasz Kacprzyk; Victoria Rydengård; Matthias Mörgelin; Mina Davoudi; mukesh pasupuleti; Martin Malmsten; Artur Schmidtchen
Antimicrobial activity of histidine-rich peptides is dependent on acidic conditions.
Biochimica et biophysica acta 2007;1768(11):2667-80.
2007: Krisztina Halász; Anja Kassner; Matthias Mörgelin; Dick Heinegård
COMP acts as a catalyst in collagen fibrillogenesis.
The Journal of biological chemistry 2007;282(43):31166-73.
2007: Naomi L Baker; Matthias Mörgelin; Rishika A Pace; Rachel Peat; Naomi E Adams; R J McKinlay Gardner; Lewis P Rowland; Geoffrey Miller; Peter De Jonghe; Berten Ceulemans; Mark C Hannibal; Matthew Edwards; Elizabeth M Thompson; Richard Jacobson; Ros C M Quinlivan; Salim Aftimos; Andrew J Kornberg; Kathryn N North; John F Bateman; Shireen R Lamandé
Molecular consequences of dominant Bethlem myopathy collagen VI mutations.
Annals of neurology 2007;62(4):390-405.
2007: Anders Wittrup; Staffan Sandgren; Johanna Lilja; Charlotte Bratt; Niklas Gustavsson; Matthias Mörgelin; Mattias Belting
Identification of proteins released by mammalian cells that mediate DNA internalization through proteoglycan-dependent macropinocytosis.
The Journal of biological chemistry 2007;282(38):27897-904.
2007: Oonagh Shannon; Erika Hertzén; Anna Norrby-Teglund; Matthias Mörgelin; Ulf Sjöbring; Lars Björck
Severe streptococcal infection is associated with M protein-induced platelet activation and thrombus formation.
Molecular microbiology 2007;65(5):1147-57.
2007: Minola Manea; AnnCharlotte Kristoffersson; Reinhard Schneppenheim; Moin A Saleem; Peter W Mathieson; Matthias Mörgelin; Peter Björk; Lars Holmberg; Diana Karpman
Podocytes express ADAMTS13 in normal renal cortex and in patients with thrombotic thrombocytopenic purpura.
British journal of haematology 2007;138(5):651-62.
2007: Ake Oldberg; Sebastian Kalamajski; Salnikov Alexei; L E B Stuhr; Matthias Mörgelin; Rolf K Reed; Nils-Erik Heldin; Kristofer Rubin
Collagen-binding proteoglycan fibromodulin can determine stroma matrix structure and fluid balance in experimental carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(35):13966-71.
2007: Lisa I Påhlman; Pauline F Marx; Matthias Mörgelin; Slawomir Lukomski; Joost C M Meijers; Heiko Herwald
Thrombin-activatable fibrinolysis inhibitor binds to Streptococcus pyogenes by interacting with collagen-like proteins A and B.
The Journal of biological chemistry 2007;282(34):24873-81.
2007: Lisa I Påhlman; Erik Malmström; Matthias Mörgelin; Heiko Herwald
M protein from Streptococcus pyogenes induces tissue factor expression and pro-coagulant activity in human monocytes.
Microbiology (Reading, England) 2007;153(Pt 8):2458-64.
2007: Martin Malmsten; Mina Davoudi; Björn Walse; Victoria Rydengård; mukesh pasupuleti; Matthias Mörgelin; Artur Schmidtchen
Antimicrobial peptides derived from growth factors.
Growth factors (Chur, Switzerland) 2007;25(1):60-70.
2007: Arndt Halbach; Matthias Mörgelin; Maria Baumgarten; Mark Milbrandt; Mats Paulsson; Markus Plomann
PACSIN 1 forms tetramers via its N-terminal F-BAR domain.
The FEBS journal 2007;274(3):773-82.
2007: Andreas Sonesson; Lovisa Ringstad; Emma Andersson Nordahl; Martin Malmsten; Matthias Mörgelin; Artur Schmidtchen
Antifungal activity of C3a and C3a-derived peptides against Candida.
Biochimica et biophysica acta 2007;1768(2):346-53.
2007: mukesh pasupuleti; Björn Walse; Emma Andersson Nordahl; Matthias Mörgelin; Martin Malmsten; Artur Schmidtchen
Preservation of antimicrobial properties of complement peptide C3a, from invertebrates to humans.
The Journal of biological chemistry 2007;282(4):2520-8.
2007: Victoria Rydengård; Anna-Karin Olsson; Matthias Mörgelin; Artur Schmidtchen
Histidine-rich glycoprotein exerts antibacterial activity.
The FEBS journal 2007;274(2):377-89.
2006: Inga-Maria Frick; Per Akesson; Heiko Herwald; Matthias Mörgelin; Martin Malmsten; Dorit Nägler; Lars Björck
The contact system--a novel branch of innate immunity generating antibacterial peptides.
The EMBO journal 2006;25(23):5569-78.
2006: Alexander J Kvist; Anna E Johnson; Matthias Mörgelin; Erika Elisabet Gustafsson; Eva Bengtsson; Karin Lindblom; Attila Aszódi; Reinhard Fässler; Takako Sasaki; Rupert Timpl; Anders Aspberg
Chondroitin sulfate perlecan enhances collagen fibril formation. Implications for perlecan chondrodysplasias.
The Journal of biological chemistry 2006;281(44):33127-39.
2006: Sara H Bengtson; Stephen B Phagoo; Anna Norrby-Teglund; Lisa Påhlman; Matthias Mörgelin; Bruce L Zuraw; L M Fredrik Leeb-Lundberg; Heiko Herwald
Kinin receptor expression during Staphylococcus aureus infection.
Blood 2006;108(6):2055-63.
2006: Johannes A Eble; Anja Kassner; Stephan Niland; Matthias Mörgelin; Joachim Grifka; Susanne Grässel
Collagen XVI harbors an integrin alpha1 beta1 recognition site in its C-terminal domains.
The Journal of biological chemistry 2006;281(35):25745-56.
2006: Lisa I Påhlman; Matthias Mörgelin; Jana Eckert; Linda Johansson; Wayne Russell; Kristian Riesbeck; Oliver Soehnlein; Lennart Lindbom; Anna Norrby-Teglund; Ralf R Schumann; Lars Björck; Heiko Herwald
Streptococcal M protein: a multipotent and powerful inducer of inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(2):1221-8.
2006: Anne-lie Ståhl; Majlis Svensson; Matthias Mörgelin; Catharina Svanborg; Phillip I Tarr; Jody C Mooney; Sandra L Watkins; Roger Johnson; Diana Karpman
Lipopolysaccharide from enterohemorrhagic Escherichia coli binds to platelets through TLR4 and CD62 and is detected on circulating platelets in patients with hemolytic uremic syndrome.
Blood 2006;108(1):167-76.
2006: Shireen R Lamandé; Matthias Mörgelin; Naomi E Adams; Carly Selan; Justin M Allen
The C5 domain of the collagen VI alpha3(VI) chain is critical for extracellular microfibril formation and is present in the extracellular matrix of cultured cells.
The Journal of biological chemistry 2006;281(24):16607-14.
2006: Maria Nilsson; Ole E Sørensen; Matthias Mörgelin; Maria Weineisen; Ulf Sjöbring; Heiko Herwald
Activation of human polymorphonuclear neutrophils by streptolysin O from Streptococcus pyogenes leads to the release of proinflammatory mediators.
Thrombosis and haemostasis 2006;95(6):982-90.
2006: Ulla M Wewer; Matthias Mörgelin; Peter Holck; Jonas Jacobsen; Magnus C Lydolph; Anders H Johnsen; Marie Kveiborg; Reidar Albrechtsen
ADAM12 is a four-leafed clover: the excised prodomain remains bound to the mature enzyme.
The Journal of biological chemistry 2006;281(14):9418-22.
2006: Leïla Staali; Susanne Bauer; Matthias Mörgelin; Lars Björck; Hans Tapper
Streptococcus pyogenes bacteria modulate membrane traffic in human neutrophils and selectively inhibit azurophilic granule fusion with phagosomes.
Cellular microbiology 2006;8(4):690-703.
2006: Sara Pellmé; Matthias Mörgelin; Hans Tapper; Ulf-Henrik Mellqvist; Claes Dahlgren; Anna Karlsson
Localization of human neutrophil interleukin-8 (CXCL-8) to organelle(s) distinct from the classical granules and secretory vesicles.
Journal of leukocyte biology 2006;79(3):564-73.
2006: D Patric Nitsche; Helena M Johansson; Inga-Maria Frick; Matthias Mörgelin
Streptococcal protein FOG, a novel matrix adhesin interacting with collagen I in vivo.
The Journal of biological chemistry 2006;281(3):1670-9.
2006: Andreas Ney; Patrick Booms; Guido Epple; Matthias Mörgelin; Gao Guo; Gerhard Kettelgerdes; Reinhard Gessner; Peter Robinson
Calcium-dependent self-association of the C-type lectin domain of versican.
The international journal of biochemistry & cell biology 2006;38(1):23-9.
2005: Emma Andersson Nordahl; Victoria Rydengård; Matthias Mörgelin; Artur Schmidtchen
Domain 5 of high molecular weight kininogen is antibacterial.
The Journal of biological chemistry 2005;280(41):34832-9.
2005: Andreas P Sjöberg; Patrik Onnerfjord; Matthias Mörgelin; Dick Heinegård; Anna Blom
The extracellular matrix and inflammation: fibromodulin activates the classical pathway of complement by directly binding C1q.
The Journal of biological chemistry 2005;280(37):32301-8.
2005: Christian Kamp Nielsen; Joan I A Campbell; John Ohd; Matthias Mörgelin; Kristian Riesbeck; Göran Landberg; Anita Sjölander
A novel localization of the G-protein-coupled CysLT1 receptor in the nucleus of colorectal adenocarcinoma cells.
Cancer research 2005;65(3):732-42.
2005: Naomi L Baker; Matthias Mörgelin; Rachel Peat; Nathalie Goemans; Kathryn N North; John F Bateman; Shireen R Lamandé
Dominant collagen VI mutations are a common cause of Ullrich congenital muscular dystrophy.
Human molecular genetics 2005;14(2):279-93.
2005: Dong Soo Kang; Caroline Gustafsson; Matthias Mörgelin; L M Fredrik Leeb-Lundberg
B1 bradykinin receptor homo-oligomers in receptor cell surface expression and signaling: effects of receptor fragments.
Molecular pharmacology 2005;67(1):309-18.
2004: Helena M Johansson; Matthias Mörgelin; Inga-Maria Frick
Protein FOG--a streptococcal inhibitor of neutrophil function.
Microbiology (Reading, England) 2004;150(Pt 12):4211-21.
2004: Emma Andersson Nordahl; Victoria Rydengård; Patrik Nyberg; D Patric Nitsche; Matthias Mörgelin; Martin Malmsten; Lars Björck; Artur Schmidtchen
Activation of the complement system generates antibacterial peptides.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(48):16879-84.
2004: Kristoffer Larsen; Ellen Tufvesson; Johan Malmström; Matthias Mörgelin; Marie Wildt; Annika Andersson; Anna Lindström; Anders Malmström; Claes-Göran AH Löfdahl; György Marko-Varga; Leif Bjermer; Gunilla Westergren-Thorsson
Presence of activated mobile fibroblasts in bronchoalveolar lavage from patients with mild asthma.
American journal of respiratory and critical care medicine 2004;170(10):1049-56.
2004: M Werthén; Mina Davoudi; Andreas Sonesson; D Patric Nitsche; Matthias Mörgelin; K Blom; Artur Schmidtchen
Pseudomonas aeruginosa-induced infection and degradation of human wound fluid and skin proteins ex vivo are eradicated by a synthetic cationic polymer.
The Journal of antimicrobial chemotherapy 2004;54(4):772-9.
2004: Anna Lundell; Anders I Olin; Matthias Mörgelin; Salam Al-Karadaghi; Anders Aspberg; Derek Logan
Structural basis for interactions between tenascins and lectican C-type lectin domains: evidence for a crosslinking role for tenascins.
Structure (London, England : 1993) 2004;12(8):1495-506.
2004: Anja Kassner; Kerstin Tiedemann; Holger Notbohm; Thomas Ludwig; Matthias Mörgelin; Ehab Ismail El=-Hallous; Mon-Li Chu; Peter Bruckner; Susanne Grässel
Molecular structure and interaction of recombinant human type XVI collagen.
Journal of molecular biology 2004;339(4):835-53.
2004: Lajos Mátés; Claudia Nicolae; Matthias Mörgelin; Ferenc Deák; Ibolya Kiss; Attila Aszódi
Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities.
Matrix biology : journal of the International Society for Matrix Biology 2004;23(3):195-204.
2004: Dong Soo Kang; Kristina Ryberg; Matthias Mörgelin; L M Fredrik Leeb-Lundberg
Spontaneous formation of a proteolytic B1 and B2 bradykinin receptor complex with enhanced signaling capacity.
The Journal of biological chemistry 2004;279(21):22102-7.
2004: Emma Andersson; Victoria Rydengård; Andreas Sonesson; Matthias Mörgelin; Lars Björck; Artur Schmidtchen
Antimicrobial activities of heparin-binding peptides.
European journal of biochemistry / FEBS 2004;271(6):1219-26.
2004: Heiko Herwald; Henning Cramer; Matthias Mörgelin; Wayne Russell; Ulla Sollenberg; Anna Norrby-Teglund; Hans Flodgaard; Lennart Lindbom; Lars Björck
M protein, a classical bacterial virulence determinant, forms complexes with fibrinogen that induce vascular leakage.
Cell 2004;116(3):367-79.
2003: Charlotte Wiberg; Andreas R Klatt; Raimund Wagener; Mats Paulsson; John F Bateman; Dick Heinegård; Matthias Mörgelin
Complexes of matrilin-1 and biglycan or decorin connect collagen VI microfibrils to both collagen II and aggrecan.
The Journal of biological chemistry 2003;278(39):37698-704.
2003: Kristin Persson; Wayne Russell; Matthias Mörgelin; Heiko Herwald
The conversion of fibrinogen to fibrin at the surface of curliated Escherichia coli bacteria leads to the generation of proinflammatory fibrinopeptides.
The Journal of biological chemistry 2003;278(34):31884-90.
2003: Martin E Lidell; Malin E V Johansson; Matthias Mörgelin; Noomi Asker; James R Gum; Young S Kim; Gunnar Hansson
The recombinant C-terminus of the human MUC2 mucin forms dimers in Chinese-hamster ovary cells and heterodimers with full-length MUC2 in LS 174T cells.
The Biochemical journal 2003;372(Pt 2):335-45.
2003: Leïla Staali; Matthias Mörgelin; Lars Björck; Hans Tapper
Streptococcus pyogenes expressing M and M-like surface proteins are phagocytosed but survive inside human neutrophils.
Cellular microbiology 2003;5(4):253-65.
2003: Terri Wells; Catherine Davidson; Matthias Mörgelin; Joseph L E Bird; Michael T Bayliss; Jayesh Dudhia
Age-related changes in the composition, the molecular stoichiometry and the stability of proteoglycan aggregates extracted from human articular cartilage.
The Biochemical journal 2003;370(Pt 1):69-79.
2003: Heiko Herwald; Matthias Mörgelin; B Dahlbäck; Lars Björck
Interactions between surface proteins of Streptococcus pyogenes and coagulation factors modulate clotting of human plasma.
Journal of thrombosis and haemostasis : JTH 2003;1(2):284-91.
2003: Heiko Herwald; Matthias Mörgelin; Lars Björck
Contact activation by pathogenic bacteria: a virulence mechanism contributing to the pathophysiology of sepsis.
Scandinavian journal of infectious diseases 2003;35(9):604-7.
2002: Charlotte Wiberg; Dick Heinegård; Christina Wenglén; Rupert Timpl; Matthias Mörgelin
Biglycan organizes collagen VI into hexagonal-like networks resembling tissue structures.
The Journal of biological chemistry 2002;277(51):49120-6.
2002: Klaus Godl; Malin E V Johansson; Martin E Lidell; Matthias Mörgelin; Hasse Karlsson; Fredrik J Olson; James R Gum; Young S Kim; Gunnar Hansson
The N terminus of the MUC2 mucin forms trimers that are held together within a trypsin-resistant core fragment.
The Journal of biological chemistry 2002;277(49):47248-56.
2002: Sabrina Cattaruzza; Monica Schiappacassi; Asa Ljungberg-Rose; Paola Spessotto; Daniela Perissinotto; Matthias Mörgelin; Maria Teresa Mucignat; Alfonso Colombatti; Roberto Perris
Distribution of PG-M/versican variants in human tissues and de novo expression of isoform V3 upon endothelial cell activation, migration, and neoangiogenesis in vitro.
The Journal of biological chemistry 2002;277(49):47626-35.
2002: Dorothea Piecha; Charlotte Wiberg; Matthias Mörgelin; Ehab Ismail El=-Hallous; Ferenc Deák; Patrik Maurer; Mats Paulsson
Matrilin-2 interacts with itself and with other extracellular matrix proteins.
The Biochemical journal 2002;367(Pt 3):715-21.
2002: Kang Feng; Xiao-Hong Zhou; Toshitaka Oohashi; Matthias Mörgelin; Ariel Lustig; Satoshi Hirakawa; Yoshifumi Ninomiya; Jürgen Engel; Uwe Rauch; Reinhard Fässler
All four members of the Ten-m/Odz family of transmembrane proteins form dimers.
The Journal of biological chemistry 2002;277(29):26128-35.
2002: Eva Bengtsson; Matthias Mörgelin; Takako Sasaki; Rupert Timpl; Dick Heinegård; Anders Aspberg
The leucine-rich repeat protein PRELP binds perlecan and collagens and may function as a basement membrane anchor.
The Journal of biological chemistry 2002;277(17):15061-8.
2002: Hans Tapper; Anna Karlsson; Matthias Mörgelin; Hans Flodgaard; Heiko Herwald
Secretion of heparin-binding protein from human neutrophils is determined by its localization in azurophilic granules and secretory vesicles.
Blood 2002;99(5):1785-93.
2002: Shireen R Lamandé; Matthias Mörgelin; Carly Selan; G Joost Jöbsis; Frank Baas; John F Bateman
Kinked collagen VI tetramers and reduced microfibril formation as a result of Bethlem myopathy and introduced triple helical glycine mutations.
The Journal of biological chemistry 2002;277(3):1949-56.
2001: B Mansson; Christina Wenglén; Matthias Mörgelin; T Saxne; Dick Heinegård
Association of chondroadherin with collagen type II.
The Journal of biological chemistry 2001;276(35):32883-8.
2001: Charlotte Wiberg; E Hedbom; A Khairullina; Shireen R Lamandé; Ake Oldberg; Rupert Timpl; Matthias Mörgelin; Dick Heinegård
Biglycan and decorin bind close to the n-terminal region of the collagen VI triple helix.
The Journal of biological chemistry 2001;276(22):18947-52.
2001: Anders I Olin; Matthias Mörgelin; Takako Sasaki; Rupert Timpl; Dick Heinegård; Anders Aspberg
The proteoglycans aggrecan and Versican form networks with fibulin-2 through their lectin domain binding.
The Journal of biological chemistry 2001;276(2):1253-61.
2001: David J (Jamie) Fitzgerald; Matthias Mörgelin; Carly Selan; Charlotte Wiberg; D R Keene; Shireen R Lamandé; John F Bateman
The N-terminal N5 subdomain of the alpha 3(VI) chain is important for collagen VI microfibril formation.
The Journal of biological chemistry 2001;276(1):187-93.
2001: Heiko Herwald; Matthias Mörgelin; H G Svensson; Ulf Sjöbring
Zinc-dependent conformational changes in domain D5 of high molecular mass kininogen modulate contact activation.
European journal of biochemistry / FEBS 2001;268(2):396-404.
2000: K Persson; Matthias Mörgelin; Lennart Lindbom; P Alm; Lars Björck; Heiko Herwald
Severe lung lesions caused by Salmonella are prevented by inhibition of the contact system.
The Journal of experimental medicine 2000;192(10):1415-24.
2000: Inga-Maria Frick; Matthias Mörgelin; Lars Björck
Virulent aggregates of Streptococcus pyogenes are generated by homophilic protein-protein interactions.
Molecular microbiology 2000;37(5):1232-47.
2000: Daniela Perissinotto; P Iacopetti; I Bellina; Roberto Doliana; Alfonso Colombatti; Z Pettway; Marianne Bronner-Fraser; T Shinomura; K Kimata; Matthias Mörgelin; J Löfberg; Roberto Perris
Avian neural crest cell migration is diversely regulated by the two major hyaluronan-binding proteoglycans PG-M/versican and aggrecan.
Development (Cambridge, England) 2000;127(13):2823-42.
2000: Andreas R Klatt; D Patric Nitsche; Birgit Kobbe; Matthias Mörgelin; Mats Paulsson; Raimund Wagener
Molecular structure and tissue distribution of matrilin-3, a filament-forming extracellular matrix protein expressed during skeletal development.
The Journal of biological chemistry 2000;275(6):3999-4006.
1999: Mercedes Costell; Erika Elisabet Gustafsson; Attila Aszódi; Matthias Mörgelin; W Bloch; Ernst B Hunziker; K Addicks; Rupert Timpl; Reinhard Fässler
Perlecan maintains the integrity of cartilage and some basement membranes.
The Journal of cell biology 1999;147(5):1109-22.
1999: GV Eriksen; Ingemar Carlstedt; Matthias Mörgelin; Niels Uldbjerg; Anders Malmström
Isolation and characterization of proteoglycans from human follicular fluid.
The Biochemical journal 1999;340 ( Pt 3)():613-20.
1999: Dorothea Piecha; Selen Catania; Matthias Mörgelin; N Hauser; D Studer; Ibolya Kiss; Mats Paulsson; Ferenc Deák
Matrilin-2, a large, oligomeric matrix protein, is expressed by a great variety of cells and forms fibrillar networks.
The Journal of biological chemistry 1999;274(19):13353-61.
1999: A Lindblom; N Quadt; T Marsh; D Aeschlimann; Matthias Mörgelin; K Mann; P Maurer; M Paulsson
The intrinsic factor-vitamin B12 receptor, cubilin, is assembled into trimers via a coiled-coil alpha-helix.
The Journal of biological chemistry 1999;274(10):6374-80.
1999: Anna Blom; Matthias Mörgelin; M Oyen; Jüri Jarvet; Erik Fries
Structural characterization of inter-alpha-inhibitor. Evidence for an extended shape.
The Journal of biological chemistry 1999;274(1):298-304.
1998: K Rosenberg; H Olsson; Matthias Mörgelin; Dick Heinegård
Cartilage oligomeric matrix protein shows high affinity zinc-dependent interaction with triple helical collagen.
The Journal of biological chemistry 1998;273(32):20397-403.
1998: Heiko Herwald; Matthias Mörgelin; Arne Olsén; M Rhen; B Dahlbäck; W Müller-Esterl; Lars Björck
Activation of the contact-phase system on bacterial surfaces--a clue to serious complications in infectious diseases.
Nature medicine 1998;4(3):298-302.