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Scott Morham

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Chemicals & Drugs

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Michael L Nickerson; Toshio Okano; Jayne S Weiss; Ludger Wessjohann; Thorkell Andresson; Allen D Bosley; Wolfgang Brandt; Dominic Esposito; Yoshihisa Hirota; Shigeru Kinoshita; Brittany N Kostiha; Howard S Kruth; Scott G Morham; Michael Dean
The UBIAD1 prenyltransferase links menaquione-4 synthesis to cholesterol metabolic enzymes.
Craig Brown; Scott G Morham; Derek Walsh; Mojgan H Naghavi
Focal adhesion proteins talin-1 and vinculin negatively affect paxillin phosphorylation and limit retroviral infection.
Matthew S Henning; Patricia Stiedl; Denis S Barry; Robert McMahon; Scott G Morham; Derek Walsh; Mojgan H Naghavi
PDZD8 is a novel moesin-interacting cytoskeletal regulatory protein that suppresses infection by herpes simplex virus type 1.

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All Publications

2013: Michael L Nickerson; Toshio Okano; Jayne S Weiss; Ludger Wessjohann; Thorkell Andresson; Allen D Bosley; Wolfgang Brandt; Dominic Esposito; Yoshihisa Hirota; Shigeru Kinoshita; Brittany N Kostiha; Howard S Kruth; Scott G Morham; Michael Dean
The UBIAD1 prenyltransferase links menaquione-4 synthesis to cholesterol metabolic enzymes.
Human mutation 2013;34(2):317-29.
2011: Craig Brown; Scott G Morham; Derek Walsh; Mojgan H Naghavi
Focal adhesion proteins talin-1 and vinculin negatively affect paxillin phosphorylation and limit retroviral infection.
Journal of molecular biology 2011;410(5):761-77.
2011: Matthew S Henning; Patricia Stiedl; Denis S Barry; Robert McMahon; Scott G Morham; Derek Walsh; Mojgan H Naghavi
PDZD8 is a novel moesin-interacting cytoskeletal regulatory protein that suppresses infection by herpes simplex virus type 1.
Virology 2011;415(2):114-21.
2010: Matthew S Henning; Scott G Morham; Stephen P Goff; Mojgan H Naghavi
PDZD8 is a novel Gag-interacting factor that promotes retroviral infection.
Journal of virology 2010;84(17):8990-5.
2010: Zachary L Demorest; Donna A MacDuff; William L Brown; Scott G Morham; Leslie V Parise; Reuben S Harris
The interaction between AID and CIB1 is nonessential for antibody gene diversification by gene conversion or class switch recombination.
PloS one 2010;5(7):e11660.
2009: Monika Bajorek; Eiji Morita; Jack J Skalicky; Scott G Morham; Markus Babst; Wesley I Sundquist
Biochemical analyses of human IST1 and its function in cytokinesis.
Molecular biology of the cell 2009;20(5):1360-73.
2007: Eiji Morita; Virginie Sandrin; Hyo-Young Chung; Scott G Morham; Steven P Gygi; Christopher K Rodesch; Wesley I Sundquist
Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis.
The EMBO journal 2007;26(19):4215-27.
2006: Naomi L Chillingworth; Scott G Morham; Lucy F Donaldson
Sex differences in inflammation and inflammatory pain in cyclooxygenase-deficient mice.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;291(2):R327-34.
2004: Melissa D Stuchell; Jennifer E Garrus; Barbara Müller; Kirsten M Stray; Sanaz Ghaffarian; Rena McKinnon; Hans-Georg Kräusslich; Scott G Morham; Wesley I Sundquist
The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding.
The Journal of biological chemistry 2004;279(34):36059-71.
2004: Jennifer L Goulet; Amy J Pace; Mikelle Key-Solle; Robert S Byrum; MyTrang Nguyen; Stephen L Tilley; Scott G Morham; Robert Langenbach; Jeffrey L Stock; John McNeish; Oliver Smithies; Thomas M Coffman; Beverly H Koller
E-prostanoid-3 receptors mediate the proinflammatory actions of prostaglandin E2 in acute cutaneous inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(2):1321-6.
2003: Uta K von Schwedler; Melissa Stuchell; Barbara Müller; Diane McVey Ward; Hyo-Young Chung; Eiji Morita; Hubert E Wang; Thaylon Davis; Gong-Ping He; Daniel M Cimbora; Anna Scott; Hans-Georg Kräusslich; Jerry Kaplan; Scott G Morham; Wesley I Sundquist
The protein network of HIV budding.
Cell 2003;114(6):701-13.
2003: Owen Pornillos; Daniel S Higginson; Kirsten M Stray; Robert D Fisher; Jennifer E Garrus; Marielle Payne; Gong-Ping He; Hubert E Wang; Scott G Morham; Wesley I Sundquist
HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein.
The Journal of cell biology 2003;162(3):425-34.
2003: Thomas Langmann; Christoph Schumacher; Scott G Morham; Christian Honer; Susanne Heimerl; Christoph Moehle; Gerd Schmitz
ZNF202 is inversely regulated with its target genes ABCA1 and apoE during macrophage differentiation and foam cell formation.
Journal of lipid research 2003;44(5):968-77.
2002: Howard F Tiano; Charles D Loftin; Jacqueline K Akunda; Christopher A Lee; Judson W Spalding; Alisha R Sessoms; David B Dunson; Eleanor G Rogan; Scott G Morham; Robert C Smart; Robert Langenbach
Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis.
Cancer research 2002;62(12):3395-401.
2002: Kathleen M Caron; Leighton R James; Hyung-Suk Kim; Scott G Morham; Maria Luisa S Sequeira Lopez; R Ariel Gomez; Timothy L Reudelhuber; Oliver Smithies
A genetically clamped renin transgene for the induction of hypertension.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):8248-52.
2002: Gudmundur Sigthorsson; Robert J Simpson; Matthew Walley; Andrew Anthony; Russell Foster; Christoph Hotz-Behoftsitz; Abbas Palizban; Joaquim Pombo; Jo Watts; Scott G Morham; Ingvar Bjarnason
COX-1 and 2, intestinal integrity, and pathogenesis of nonsteroidal anti-inflammatory drug enteropathy in mice.
Gastroenterology 2002;122(7):1913-23.
2001: Jennifer E Garrus; Uta K von Schwedler; Owen Pornillos; Scott G Morham; K H Zavitz; Hubert E Wang; D A Wettstein; Kirsten M Stray; M Côté; Rebecca L Rich; David G Myszka; Wesley I Sundquist
Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding.
Cell 2001;107(1):55-65.
2001: X Zhang; Scott G Morham; Robert Langenbach; DA Young; L Xing; B F Boyce; Edward J Puzas; Randy N Rosier; Regis J O'Keefe; Edward M Schwarz
Evidence for a direct role of cyclo-oxygenase 2 in implant wear debris-induced osteolysis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(4):660-70.
2001: Charles D Loftin; Darshini B Trivedi; Howard F Tiano; J A Clark; Christopher A Lee; J A Epstein; Scott G Morham; Matthew D Breyer; M Nguyen; B M Hawkins; J L Goulet; Oliver Smithies; Beverly H Koller; Robert Langenbach
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(3):1059-64.
2000: Patricia C Chulada; M B Thompson; JF Mahler; C M Doyle; B W Gaul; C Lee; Howard F Tiano; Scott G Morham; Oliver Smithies; Robert Langenbach
Genetic disruption of Ptgs-1, as well as Ptgs-2, reduces intestinal tumorigenesis in Min mice.
Cancer research 2000;60(17):4705-8.
2000: Rachel E Rempel; M T Saenz-Robles; Robert W Storms; Scott G Morham; Seiichi Ishida; A Engel; L Jakoi; M F Melhem; J M Pipas; Clay Smith; Joseph R Nevins
Loss of E2F4 activity leads to abnormal development of multiple cellular lineages.
Molecular cell 2000;6(2):293-306.
2000: Olivier Morteau; Scott G Morham; Rance K Sellon; Levinus A Dieleman; Robert Langenbach; Oliver Smithies; Ryan Sartor
Impaired mucosal defense to acute colonic injury in mice lacking cyclooxygenase-1 or cyclooxygenase-2.
The Journal of clinical investigation 2000;105(4):469-78.
2000: X Zhang; Scott G Morham; Robert Langenbach; R B Baggs; DA Young
Lack of cyclooxygenase-2 inhibits growth of teratocarcinomas in mice.
Experimental cell research 2000;254(2):232-40.
1999: srinivasa reddy; Howard F Tiano; Robert Langenbach; Scott G Morham; Harvey R Herschman
Genetic evidence for distinct roles of COX-1 and COX-2 in the immediate and delayed phases of prostaglandin synthesis in mast cells.
Biochemical and biophysical research communications 1999;265(1):205-10.
1999: X Zhang; Scott G Morham; Robert Langenbach; DA Young
Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts.
The Journal of experimental medicine 1999;190(4):451-59.
1999: Barbara J Davis; D E Lennard; Christopher A Lee; Howard F Tiano; Scott G Morham; William C Wetsel; Robert Langenbach
Anovulation in cyclooxygenase-2-deficient mice is restored by prostaglandin E2 and interleukin-1beta.
Endocrinology 1999;140(6):2685-95.
1997: Scott G Morham; Robert Langenbach; JF Mahler; Oliver Smithies
Characterization of prostaglandin H synthase 2 deficient mice and implications for mechanisms of NSAID action.
Advances in experimental medicine and biology 1997;407():131-8.
1997: Robert Langenbach; Scott G Morham; Howard F Tiano; Charles D Loftin; Burhan I Ghanayem; Patricia C Chulada; JF Mahler; Barbara J Davis; Christopher A Lee
Disruption of the mouse cyclooxygenase 1 gene. Characteristics of the mutant and areas of future study.
Advances in experimental medicine and biology 1997;407():87-92.
1996: Scott G Morham; K D Kluckman; N Voulomanos; Oliver Smithies
Targeted disruption of the mouse topoisomerase I gene by camptothecin selection.
Molecular and cellular biology 1996;16(12):6804-9.
1996: Joel Mahler; Barbara J Davis; Scott G Morham; Robert Langenbach
Disruption of cyclooxygenase genes in mice.
Toxicologic pathology 1996;24(6):717-9.
1996: P T Bozza; J L Payne; Scott G Morham; R Langenbach; Oliver Smithies; Peter Weller
Leukocyte lipid body formation and eicosanoid generation: cyclooxygenase-independent inhibition by aspirin.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(20):11091-6.
1995: Robert Langenbach; Scott G Morham; Howard F Tiano; Charles D Loftin; B I Ghanayem; Patricia C Chulada; Joel Mahler; Christopher A Lee; Eugenia H Goulding; K D Kluckman; Hyung-Suk Kim; Oliver Smithies
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.
Cell 1995;83(3):483-92.
1995: Scott G Morham; Robert Langenbach; Charles D Loftin; Howard F Tiano; N Vouloumanos; John Jennette; Joel Mahler; K D Kluckman; A Ledford; Christopher A Lee; Oliver Smithies
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse.
Cell 1995;83(3):473-82.