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Toshio Morikawa

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Living Beings

Chemicals & Drugs

Genes & Molecular Sequences

Molecular Structure

Concepts & Ideas

Structure-Activity Relationship

Phenomena

Anatomy

Peritoneal Macrophages

Physiology

Cell Degranulation

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Co-Publications
Name
90
Yoshikawa, Masayuki
88
Matsuda, Hisashi
16
Ninomiya, Kiyofumi
14
Toguchida, Iwao
10
Pongpiriyadacha, Yutana
10
Muraoka, Osamu
10
Nakamura, Seikou
8
Ando, Shin
7
Harima, Shoichi
6
Murakami, Toshiyuki
6
Xie, Haihui
5
xu, fengming
5
Nishida, Norihisa
5
Kageura, Tadashi
4
Asao, Yasunobu

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Publications

TOP 3
Morikawa Toshio; Yamaguchi Itadaki; Matsuda Hisashi; Yoshikawa Masayuki
A new amide, piperchabamide F, and two new phenylpropanoid glycosides, piperchabaosides A and B, from the fruit of Piper chaba.
Matsuda Hisashi; Ninomiya Kiyofumi; Morikawa Toshio; Yasuda Daisuke; Yamaguchi Itadaki; Yoshikawa Masayuki
Hepatoprotective amide constituents from the fruit of Piper chaba: Structural requirements, mode of action, and new amides.
Yoshikawa Masayuki; Morikawa Toshio; Oominami Hideo; Matsuda Hisashi
Absolute stereostructures of olibanumols A, B, C, H, I, and J from olibanum, gum-resin of Boswellia carterii, and inhibitors of nitric oxide production in lipopolysaccharide-activated mouse peritoneal macrophages.

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All Publications

2009: Morikawa Toshio; Yamaguchi Itadaki; Matsuda Hisashi; Yoshikawa Masayuki
A new amide, piperchabamide F, and two new phenylpropanoid glycosides, piperchabaosides A and B, from the fruit of Piper chaba.
Chemical & pharmaceutical bulletin 2009;57(11):1292-5.
2009: Matsuda Hisashi; Ninomiya Kiyofumi; Morikawa Toshio; Yasuda Daisuke; Yamaguchi Itadaki; Yoshikawa Masayuki
Hepatoprotective amide constituents from the fruit of Piper chaba: Structural requirements, mode of action, and new amides.
Bioorganic & medicinal chemistry 2009;17(20):7313-23.
2009: Yoshikawa Masayuki; Morikawa Toshio; Oominami Hideo; Matsuda Hisashi
Absolute stereostructures of olibanumols A, B, C, H, I, and J from olibanum, gum-resin of Boswellia carterii, and inhibitors of nitric oxide production in lipopolysaccharide-activated mouse peritoneal macrophages.
Chemical & pharmaceutical bulletin 2009;57(9):957-64.
2009: Morikawa Toshio; Wang Li-Bo; Ninomiya Kiyofumi; Nakamura Seikou; Matsuda Hisashi; Muraoka Osamu; Wu Li-Jun; Yoshikawa Masayuki
Medicinal flowers. XXX. Eight new glycosides, everlastosides F-M, from the flowers of Helichrysum arenarium.
Chemical & pharmaceutical bulletin 2009;57(8):853-9.
2009: Morikawa Toshio; Xie Yuanyuan; Asao Yasunobu; Okamoto Masaki; Yamashita Chihiro; Muraoka Osamu; Matsuda Hisashi; Pongpiriyadacha Yutana; Yuan Dan; Yoshikawa Masayuki
Oleanane-type triterpene oligoglycosides with pancreatic lipase inhibitory activity from the pericarps of Sapindus rarak.
Phytochemistry 2009;70(9):1166-72.
2009: Morikawa Toshio; Xie Haihui; Wang Tao; Matsuda Hisashi; Yoshikawa Masayuki
Acylated flavonol bisdesmosides, sinocrassosides A3-A7 and B3, with aminopeptidase N inhibitory activity from Sinocrassula indica.
Chemistry & biodiversity 2009;6(3):411-20.
2009: Asao Yasunobu; Morikawa Toshio; Xie Yuanyuan; Okamoto Masaki; Hamao Makoto; Matsuda Hisashi; Muraoka Osamu; Yuan Dan; Yoshikawa Masayuki
Structures of acetylated oleanane-type triterpene saponins, rarasaponins IV, V, and VI, and anti-hyperlipidemic constituents from the pericarps of Sapindus rarak.
Chemical & pharmaceutical bulletin 2009;57(2):198-203.
2008: Nakamura Seikou; Okazaki Yoshie; Ninomiya Kiyofumi; Morikawa Toshio; Matsuda Hisashi; Yoshikawa Masayuki
Medicinal flowers. XXIV. Chemical structures and hepatoprotective effects of constituents from flowers of Hedychium coronarium.
Chemical & pharmaceutical bulletin 2008;56(12):1704-9.
2008: Morikawa Toshio; Xie Haihui; Wang Tao; Matsuda Hisashi; Yoshikawa Masayuki
Bioactive constituents from Chinese natural medicines. XXXII. aminopeptidase N and aldose reductase inhibitors from Sinocrassula indica: structures of sinocrassosides B(4), B(5), C(1), and D(1)-D(3).
Chemical & pharmaceutical bulletin 2008;56(10):1438-44.
2008: Yoshikawa Masayuki; Li Xuezheng; Nishida Eriko; Nakamura Seikou; Matsuda Hisashi; Muraoka Osamu; Morikawa Toshio
Medicinal flowers. XXI. Structures of perennisaponins A, B, C, D, E, and F, acylated oleanane-type triterpene oligoglycosides, from the flowers of Bellis perennis.
Chemical & pharmaceutical bulletin 2008;56(4):559-68.
2008: Matsuda Hisashi; Ninomiya Kiyofumi; Morikawa Toshio; Yasuda Daisuke; Yamaguchi Itadaki; Yoshikawa Masayuki
Protective effects of amide constituents from the fruit of Piper chaba on D-galactosamine/TNF-alpha-induced cell death in mouse hepatocytes.
Bioorganic & medicinal chemistry letters 2008;18(6):2038-42.
2007: Yoshikawa Masayuki; Wang Tao; Morikawa Toshio; Xie Haihui; Matsuda Hisashi
Bioactive constituents from chinese natural medicines. XXIV. Hypoglycemic effects of Sinocrassula indica in sugar-loaded rats and genetically diabetic KK-A(y) mice and structures of new acylated flavonol glycosides, sinocrassosides A(1), A(2), B(1), and B(2).
Chemical & pharmaceutical bulletin 2007;55(9):1308-15.
2007: Ninomiya Kiyofumi; Matsuda Hisashi; Kubo Mizuho; Morikawa Toshio; Nishida Norihisa; Yoshikawa Masayuki
Potent anti-obese principle from Rosa canina: structural requirements and mode of action of trans-tiliroside.
Bioorganic & medicinal chemistry letters 2007;17(11):3059-64.
2007: Yoshikawa Masayuki; Morikawa Toshio; Zhang Yi; Nakamura Seikou; Muraoka Osamu; Matsuda Hisashi
Megastigmanes and their glucosides from the whole plant of Sedum sarmentosum.
Journal of natural products 2007;70(4):575-83.
2007: Morikawa Toshio; Zhang Yi; Nakamura Seikou; Matsuda Hisashi; Muraoka Osamu; Yoshikawa Masayuki
Bioactive constituents from Chinese natural medicines. XXII. Absolute structures of new megastigmane glycosides, sedumosides E1, E2, E3, F1, F2, and G, from Sedum sarmentosum (Crassulaceae).
Chemical & pharmaceutical bulletin 2007;55(3):435-41.
2007: Yoshikawa Masayuki; Morikawa Toshio; Kobayashi Hisanori; Nakamura Akihiko; Matsuhira Koudai; Nakamura Seikou; Matsuda Hisashi
Bioactive saponins and glycosides. XXVII. Structures of new cucurbitane-type triterpene glycosides and antiallergic constituents from Citrullus colocynthis.
Chemical & pharmaceutical bulletin 2007;55(3):428-34.
2007: Yoshikawa Masayuki; Xu Fengming; Morikawa Toshio; Pongpiriyadacha Yutana; Nakamura Seikou; Asao Yasunobu; Kumahara Akira; Matsuda Hisashi
Medicinal flowers. XII.(1)) New spirostane-type steroid saponins with antidiabetogenic activity from Borassus flabellifer.
Chemical & pharmaceutical bulletin 2007;55(2):308-16.
2007: Morikawa Toshio; Nakamura Seikou; Kato Yasuyo; Muraoka Osamu; Matsuda Hisashi; Yoshikawa Masayuki
Bioactive saponins and glycosides. XXVIII. New triterpene saponins, foliatheasaponins I, II, III, IV, and V, from Tencha (the leaves of Camellia sinensis).
Chemical & pharmaceutical bulletin 2007;55(2):293-8.
2007: Yoshikawa Masayuki; Nakamura Seikou; Ozaki Kenichi; Kumahara Akira; Morikawa Toshio; Matsuda Hisashi
Structures of steroidal alkaloid oligoglycosides, robeneosides A and B, and antidiabetogenic constituents from the Brazilian medicinal plant Solanum lycocarpum.
Journal of natural products 2007;70(2):210-4.
2007: Matsuda Hisashi; Sugimoto Sachiko; Morikawa Toshio; Matsuhira Koudai; Mizuguchi Eri; Nakamura Seikou; Yoshikawa Masayuki
Bioactive constituents from Chinese natural medicines. XX. Inhibitors of antigen-induced degranulation in RBL-2H3 cells from the seeds of Psoralea corylifolia.
Chemical & pharmaceutical bulletin 2007;55(1):106-10.
2007: Yoshikawa Masayuki; Morikawa Toshio; Nakamura Seikou; Li Ning; Li Xian; Matsuda Hisashi
Bioactive saponins and glycosides. XXV. Acylated oleanane-type triterpene saponins from the seeds of tea plant (Camellia sinensis).
Chemical & pharmaceutical bulletin 2007;55(1):57-63.
2006: Morikawa Toshio; Xu Fengming; Matsuda Hisashi; Yoshikawa Masayuki
Structures of new flavonoids, erycibenins D, E, and F, and NO production inhibitors from Erycibe expansa originating in Thailand.
Chemical & pharmaceutical bulletin 2006;54(11):1530-4.
2006: Yoshikawa Masayuki; Matsuda Hisashi; Morikawa Toshio; Xie Haihui; Nakamura Seikou; Muraoka Osamu
Phenylethanoid oligoglycosides and acylated oligosugars with vasorelaxant activity from Cistanche tubulosa.
Bioorganic & medicinal chemistry 2006;14(22):7468-75.
2006: Morikawa Toshio; Xie Haihui; Matsuda Hisashi; Yoshikawa Masayuki
Glucosyloxybenzyl 2-Isobutylmalates from the tubers of Gymnadenia conopsea.
Journal of natural products 2006;69(6):881-6.
2006: Xie Haihui; Morikawa Toshio; Matsuda Hisashi; Nakamura Seikou; Muraoka Osamu; Yoshikawa Masayuki
Monoterpene constituents from Cistanche tubulosa--chemical structures of kankanosides A-E and kankanol-.
Chemical & pharmaceutical bulletin 2006;54(5):669-75.
2006: Shimoda Hiroshi; Tanaka Junji; Yamada Emi; Morikawa Toshio; Kasajima Naoki; Yoshikawa Masayuki
Anti type I allergic property of Japanese butterbur extract and its mast cell degranulation inhibitory ingredients.
Journal of agricultural and food chemistry 2006;54(8):2915-20.
2006: Morikawa Toshio; Xie Haihui; Matsuda Hisashi; Wang Tao; Yoshikawa Masayuki
Bioactive constituents from Chinese natural medicines. XVII. constituents with radical scavenging effect and new glucosyloxybenzyl 2-isobutylmalates from Gymnadenia conopsea.
Chemical & pharmaceutical bulletin 2006;54(4):506-13.
2006: Morikawa Toshio; Li Ning; Nagatomo Akifumi; Matsuda Hisashi; Li Xian; Yoshikawa Masayuki
Triterpene saponins with gastroprotective effects from tea seed (the seeds of Camellia sinensis).
Journal of natural products 2006;69(2):185-90.
2006: Yoshikawa Masayuki; Nishida Norihisa; Ninomiya Kiyofumi; Ohgushi Teruki; Kubo Mizuho; Morikawa Toshio; Matsuda Hisashi
Inhibitory effects of coumarin and acetylene constituents from the roots of Angelica furcijuga on D-galactosamine/lipopolysaccharide-induced liver injury in mice and on nitric oxide production in lipopolysaccharide-activated mouse peritoneal macrophages.
Bioorganic & medicinal chemistry 2006;14(2):456-63.
2006: Matsuda Hisashi; Ando Shin; Kato Tomoko; Morikawa Toshio; Yoshikawa Masayuki
Inhibitors from the rhizomes of Alpinia officinarum on production of nitric oxide in lipopolysaccharide-activated macrophages and the structural requirements of diarylheptanoids for the activity.
Bioorganic & medicinal chemistry 2006;14(1):138-42.
2005: Yoshikawa Masayuki; Morikawa Toshio; Li Ning; Nagatomo Akifumi; Li Xian; Matsuda Hisashi
Bioactive saponins and glycosides. XXIII. Triterpene saponins with gastroprotective effect from the seeds of Camellia sinensis--theasaponins E3, E4, E5, E6, and E7.
Chemical & pharmaceutical bulletin 2005;53(12):1559-64.
2005: Xie Haihui; Wang Tao; Matsuda Hisashi; Morikawa Toshio; Yoshikawa Masayuki; Tani Tadato
Bioactive constituents from Chinese natural medicines. XV. Inhibitory effect on aldose reductase and structures of Saussureosides A and B from Saussurea medusa.
Chemical & pharmaceutical bulletin 2005;53(11):1416-22.
2005: Yoshikawa Masayuki; Morikawa Toshio; Yamamoto Kaori; Kato Yasuyo; Nagatomo Akifumi; Matsuda Hisashi
Floratheasaponins A-C, acylated oleanane-type triterpene oligoglycosides with anti-hyperlipidemic activities from flowers of the tea plant (Camellia sinensis).
Journal of natural products 2005;68(9):1360-5.
2005: Morikawa Toshio; Ando Shin; Matsuda Hisashi; Kataoka Shinya; Muraoka Osamu; Yoshikawa Masayuki
Inhibitors of nitric oxide production from the rhizomes of Alpinia galanga: structures of new 8-9' linked neolignans and sesquineolignan.
Chemical & pharmaceutical bulletin 2005;53(6):625-30.
2005: Ando Shin; Matsuda Hisashi; Morikawa Toshio; Yoshikawa Masayuki
1'S-1'-Acetoxychavicol acetate as a new type inhibitor of interferon-beta production in lipopolysaccharide-activated mouse peritoneal macrophages.
Bioorganic & medicinal chemistry 2005;13(9):3289-94.
2005: Matsuda Hisashi; Ando Shin; Morikawa Toshio; Kataoka Shinya; Yoshikawa Masayuki
Structure-activity relationships of 1'S-1'-acetoxychavicol acetate for inhibitory effect on NO production in lipopolysaccharide-activated mouse peritoneal macrophages.
Bioorganic & medicinal chemistry letters 2005;15(7):1949-53.
2004: Morikawa Toshio; Matsuda Hisashi; Nishida Norihisa; Ohgushi Teruki; Yoshikawa Masayuki
Structures of new aromatics glycosides from a Japanese folk medicine, the roots of Angelica furcijuga.
Chemical & pharmaceutical bulletin 2004;52(11):1387-90.
2004: Matsuda Hisashi; Tewtrakul Supinya; Morikawa Toshio; Nakamura Akihiko; Yoshikawa Masayuki
Anti-allergic principles from Thai zedoary: structural requirements of curcuminoids for inhibition of degranulation and effect on the release of TNF-alpha and IL-4 in RBL-2H3 cells.
Bioorganic & medicinal chemistry 2004;12(22):5891-8.
2004: Sun Bohang; Morikawa Toshio; Matsuda Hisashi; Tewtrakul Supinya; Wu Li Jun; Harima Shoichi; Yoshikawa Masayuki
Structures of new beta-carboline-type alkaloids with antiallergic effects from Stellaria dichotoma(1,2).
Journal of natural products 2004;67(9):1464-9.
2004: Matsuda Hisashi; Morikawa Toshio; Xie Haihui; Yoshikawa Masayuki
Antiallergic phenanthrenes and stilbenes from the tubers of Gymnadenia conopsea.
Planta medica 2004;70(9):847-55.
2004: Matsuda Hisashi; Tewtrakul Supinya; Morikawa Toshio; Yoshikawa Masayuki
Anti-allergic activity of stilbenes from Korean rhubarb (Rheum undulatum L.): structure requirements for inhibition of antigen-induced degranulation and their effects on the release of TNF-alpha and IL-4 in RBL-2H3 cells.
Bioorganic & medicinal chemistry 2004;12(18):4871-6.
2004: Matsuda Hisashi; Morikawa Toshio; Ando Shin; Oominami Hideo; Murakami Toshiyuki; Kimura Ikuko; Yoshikawa Masayuki
Absolute stereostructures of polypodane- and octanordammarane-type triterpenes with nitric oxide production inhibitory activity from guggul-gum resins.
Bioorganic & medicinal chemistry 2004;12(11):3037-46.
2004: Xu Fengming; Morikawa Toshio; Matsuda Hisashi; Ninomiya Kiyofumi; Yoshikawa Masayuki
Structures of new sesquiterpenes and hepatoprotective constituents from the Egyptian herbal medicine Cyperus longus.
Journal of natural products 2004;67(4):569-76.
2004: Morikawa Toshio; Xu Fengming; Ninomiya Kiyofumi; Matsuda Hisashi; Yoshikawa Masayuki
Nigellamines A3, A4, A5, and C, new dolabellane-type diterpene alkaloids, with lipid metabolism-promoting activities from the Egyptian medicinal food black cumin.
Chemical & pharmaceutical bulletin 2004;52(4):494-7.
2004: Ninomiya Kiyofumi; Matsuda Hisashi; Shimoda Hiroshi; Nishida Norihisa; Kasajima Naoki; Yoshino Tomoe; Morikawa Toshio; Yoshikawa Masayuki
Carnosic acid, a new class of lipid absorption inhibitor from sage.
Bioorganic & medicinal chemistry letters 2004;14(8):1943-6.
2004: Morikawa Toshio; Xu Fengming; Kashima Yousuke; Matsuda Hisashi; Ninomiya Kiyofumi; Yoshikawa Masayuki
Novel dolabellane-type diterpene alkaloids with lipid metabolism promoting activities from the seeds of Nigella sativa.
Organic letters 2004;6(6):869-72.
2004: Morikawa Toshio; Matsuda Hisashi; Yamaguchi Itadaki; Pongpiriyadacha Yutana; Yoshikawa Masayuki
New amides and gastroprotective constituents from the fruit of Piper chaba.
Planta medica 2004;70(2):152-9.
2003: Matsuda Hisashi; Morikawa Toshio; Oda Mamiko; Asao Yasunobu; Yoshikawa Masayuki
Potent anti-metastatic activity of dimeric sesquiterpene thioalkaloids from the rhizome of Nuphar pumilum.
Bioorganic & medicinal chemistry letters 2003;13(24):4445-9.
2003: Yoshikawa Masayuki; Pongpiriyadacha Yutana; Kishi Akinobu; Kageura Tadashi; Wang Tao; Morikawa Toshio; Matsuda Hisashi
[Biological activities of Salacia chinensis originating in Thailand: the quality evaluation guided by alpha-glucosidase inhibitory activity]
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2003;123(10):871-80.
2003: Matsuda Hisashi; Morikawa Toshio; Managi Hiromi; Yoshikawa Masayuki
Antiallergic principles from Alpinia galanga: structural requirements of phenylpropanoids for inhibition of degranulation and release of TNF-alpha and IL-4 in RBL-2H3 cells.
Bioorganic & medicinal chemistry letters 2003;13(19):3197-202.
2003: Morikawa Toshio; Kishi Akinobu; Pongpiriyadacha Yutana; Matsuda Hisashi; Yoshikawa Masayuki
Structures of new friedelane-type triterpenes and eudesmane-type sesquiterpene and aldose reductase inhibitors from Salacia chinensis.
Journal of natural products 2003;66(9):1191-6.
2003: Kishi Akinobu; Morikawa Toshio; Matsuda Hisashi; Yoshikawa Masayuki
Structures of new friedelane- and norfriedelane-type triterpenes and polyacylated eudesmane-type sesquiterpene from Salacia chinensis LINN. (S. prinoides DC., Hippocrateaceae) and radical scavenging activities of principal constituents.
Chemical & pharmaceutical bulletin 2003;51(9):1051-5.
2003: Yoshikawa Masayuki; Morikawa Toshio; Kashima Yousuke; Ninomiya Kiyofumi; Matsuda Hisashi
Structures of new dammarane-type Triterpene Saponins from the flower buds of Panax notoginseng and hepatoprotective effects of principal Ginseng Saponins.
Journal of natural products 2003;66(7):922-7.
2003: Matsuda Hisashi; Pongpiriyadacha Yutana; Morikawa Toshio; Ochi Momotaro; Yoshikawa Masayuki
Gastroprotective effects of phenylpropanoids from the rhizomes of Alpinia galanga in rats: structural requirements and mode of action.
European journal of pharmacology 2003;471(1):59-67.
2003: Morikawa Toshio; Tao Jing; Ando Shin; Matsuda Hisashi; Yoshikawa Masayuki
Absolute stereostructures of new arborinane-type triterpenoids and inhibitors of nitric oxide production from Rubia yunnanensis.
Journal of natural products 2003;66(5):638-45.
2003: Pongpiriyadacha Yutana; Matsuda Hisashi; Morikawa Toshio; Asao Yasunobu; Yoshikawa Masayuki
Protective effects of polygodial on gastric mucosal lesions induced by necrotizing agents in rats and the possible mechanisms of action.
Biological & pharmaceutical bulletin 2003;26(5):651-7.
2003: Matsuda Hisashi; Morikawa Toshio; Ando Shin; Toguchida Iwao; Yoshikawa Masayuki
Structural requirements of flavonoids for nitric oxide production inhibitory activity and mechanism of action.
Bioorganic & medicinal chemistry 2003;11(9):1995-2000.
2003: Matsuda Hisashi; Morikawa Toshio; Ishiwada Tomoko; Managi Hiromi; Kagawa Masatomo; Higashi Yoshihiko; Yoshikawa Masayuki
Medicinal flowers. VIII. Radical scavenging constituents from the flowers of Prunus mume: structure of prunose III.
Chemical & pharmaceutical bulletin 2003;51(4):440-3.
2003: Matsuda Hisashi; Pongpiriyadacha Yutana; Morikawa Toshio; Kishi Akinobu; Kataoka Shinya; Yoshikawa Masayuki
Protective effects of steroid saponins from Paris polyphylla var. yunnanensis on ethanol- or indomethacin-induced gastric mucosal lesions in rats: structural requirement for activity and mode of action.
Bioorganic & medicinal chemistry letters 2003;13(6):1101-6.
2003: Yoshikawa Masayuki; Xu Fengming; Morikawa Toshio; Ninomiya Kiyofumi; Matsuda Hisashi
Anastatins A and B, new skeletal flavonoids with hepatoprotective activities from the desert plant Anastatica hierochuntica.
Bioorganic & medicinal chemistry letters 2003;13(6):1045-9.
2003: Matsuda Hisashi; Toguchida Iwao; Ninomiya Kiyofumi; Kageura Tadashi; Morikawa Toshio; Yoshikawa Masayuki
Effects of sesquiterpenes and amino acid-sesquiterpene conjugates from the roots of Saussurea lappa on inducible nitric oxide synthase and heat shock protein in lipopolysaccharide-activated macrophages.
Bioorganic & medicinal chemistry 2003;11(5):709-15.
2003: Morikawa Toshio; Tao Jing; Toguchida Iwao; Matsuda Hisashi; Yoshikawa Masayuki
Structures of new cyclic diarylheptanoids and inhibitors of nitric oxide production from Japanese folk medicine Acer nikoense.
Journal of natural products 2003;66(1):86-91.
2003: Shimoda Hiroshi; Ninomiya Kiyofumi; Nishida Norihisa; Yoshino Tomoe; Morikawa Toshio; Matsuda Hisashi; Yoshikawa Masayuki
Anti-hyperlipidemic sesquiterpenes and new sesquiterpene glycosides from the leaves of artichoke (Cynara scolymus L.): structure requirement and mode of action.
Bioorganic & medicinal chemistry letters 2003;13(2):223-8.
2002: Tao Jing; Morikawa Toshio; Toguchida Iwao; Ando Shin; Matsuda Hisashi; Yoshikawa Masayuki
Inhibitors of nitric oxide production from the bark of Myrica rubra: structures of new biphenyl type diarylheptanoid glycosides and taraxerane type triterpene.
Bioorganic & medicinal chemistry 2002;10(12):4005-12.
2002: Yoshikawa Masayuki; Morikawa Toshio; Nakano Kyoko; Pongpiriyadacha Yutana; Murakami Toshiyuki; Matsuda Hisashi
Characterization of new sweet triterpene saponins from Albizia myriophylla.
Journal of natural products 2002;65(11):1638-42.
2002: Morikawa Toshio; Matsuda Hisashi; Toguchida Iwao; Ueda Kazuho; Yoshikawa Masayuki
Absolute stereostructures of three new sesquiterpenes from the fruit of Alpinia oxyphylla with inhibitory effects on nitric oxide production and degranulation in RBL-2H3 cells.
Journal of natural products 2002;65(10):1468-74.
2002: Mastuda Hisashi; Morikawa Toshio; Ueda Kazuho; Managi Hiromi; Yoshikawa Masayuki
Structural requirements of flavonoids for inhibition of antigen-Induced degranulation, TNF-alpha and IL-4 production from RBL-2H3 cells.
Bioorganic & medicinal chemistry 2002;10(10):3123-8.
2002: Yoshikawa Masayuki; Murakami Toshiyuki; Ishiwada Tomoko; Morikawa Toshio; Kagawa Masatomo; Higashi Yoshihiko; Matsuda Hisashi
New flavonol oligoglycosides and polyacylated sucroses with inhibitory effects on aldose reductase and platelet aggregation from the flowers of Prunus mume.
Journal of natural products 2002;65(8):1151-5.
2002: Matsuda Hisashi; Morikawa Toshio; Toguchida Iwao; Harima Shoichi; Yoshikawa Masayuki
Medicinal flowers. VI. Absolute stereostructures of two new flavanone glycosides and a phenylbutanoid glycoside from the flowers of Chrysanthemum indicum L.: their inhibitory activities for rat lens aldose reductase.
Chemical & pharmaceutical bulletin 2002;50(7):972-5.
2002: Matsuda Hisashi; Morikawa Toshio; Toguchida Iwao; Yoshikawa Masayuki
Structural requirements of flavonoids and related compounds for aldose reductase inhibitory activity.
Chemical & pharmaceutical bulletin 2002;50(6):788-95.
2002: Morikawa Toshio; Matsuda Hisashi; Ninomiya Kiyofumi; Yoshikawa Masayuki
Medicinal foodstuffs. XXIX. Potent protective effects of sesquiterpenes and curcumin from Zedoariae Rhizoma on liver injury induced by D-galactosamine/lipopolysaccharide or tumor necrosis factor-alpha.
Biological & pharmaceutical bulletin 2002;25(5):627-31.
2002: Yoshikawa Masayuki; Morikawa Toshio; Matsuda Hisashi; Tanabe Genzoh; Muraoka Osamu
Absolute stereostructure of potent alpha-glucosidase inhibitor, Salacinol, with unique thiosugar sulfonium sulfate inner salt structure from Salacia reticulata.
Bioorganic & medicinal chemistry 2002;10(5):1547-54.
2002: Matsuda Hisashi; Morikawa Toshio; Tao Jing; Ueda Kazuho; Yoshikawa Masayuki
Bioactive constituents of Chinese natural medicines. VII. Inhibitors of degranulation in RBL-2H3 cells and absolute stereostructures of three new diarylheptanoid glycosides from the bark of Myrica rubra.
Chemical & pharmaceutical bulletin 2002;50(2):208-15.
2002: Matsuda Hisashi; Pongpiriyadacha Yutana; Morikawa Toshio; Kashima Yousuke; Nakano Kyoko; Yoshikawa Masayuki
Protective effects of polygodial and related compounds on ethanol-induced gastric mucosal lesions in rats: structural requirements and mode of action.
Bioorganic & medicinal chemistry letters 2002;12(3):477-82.
2001: Matsuda H; Morikawa T; Toguchida I; Ninomiya K; Yoshikawa M
Medicinal foodstuffs. XXVIII. Inhibitors of nitric oxide production and new sesquiterpenes, zedoarofuran, 4-epicurcumenol, neocurcumenol, gajutsulactones A and B, and zedoarolides A and B, from Zedoariae Rhizoma.
Chemical & pharmaceutical bulletin 2001;49(12):1558-66.
2001: Yoshikawa M; Morikawa T; Yashiro K; Murakami T; Matsuda H
Bioactive saponins and glycosides. XIX. Notoginseng (3): immunological adjuvant activity of notoginsenosides and related saponins: structures of notoginsenosides-L, -M, and -N from the roots of Panax notoginseng (Burk.) F. H. Chen.
Chemical & pharmaceutical bulletin 2001;49(11):1452-6.
2001: Matsuda H; Morikawa T; Ueda H; Yoshikawa M
Medicinal foodstuffs. XXVII. Saponin constituents of gotu kola (2): structures of new ursane- and oleanane-type triterpene oligoglycosides, centellasaponins B, C, and D, from Centella asiatica cultivated in Sri Lanka.
Chemical & pharmaceutical bulletin 2001;49(10):1368-71.
2001: Muraoka O; Fujimoto M; Tanabe G; Kubo M; Minematsu T; Matsuda H; Morikawa T; Toguchida I; Yoshikawa M
Absolute stereostructures of novel norcadinane- and trinoreudesmane-type sesquiterpenes with nitric oxide production inhibitory activity from Alpinia oxyphylla.
Bioorganic & medicinal chemistry letters 2001;11(16):2217-20.
2001: Matsuda H; Shimoda H; Morikawa T; Yoshikawa M
Phytoestrogens from the roots of Polygonum cuspidatum (Polygonaceae): structure-requirement of hydroxyanthraquinones for estrogenic activity.
Bioorganic & medicinal chemistry letters 2001;11(14):1839-42.
2001: Kageura T; Matsuda H; Morikawa T; Toguchida I; Harima S; Oda M; Yoshikawa M
Inhibitors from rhubarb on lipopolysaccharide-induced nitric oxide production in macrophages: structural requirements of stilbenes for the activity.
Bioorganic & medicinal chemistry 2001;9(7):1887-93.
2001: Matsuda H; Kageura T; Oda M; Morikawa T; Sakamoto Y; Yoshikawa M
Effects of constituents from the bark of Magnolia obovata on nitric oxide production in lipopolysaccharide-activated macrophages.
Chemical & pharmaceutical bulletin 2001;49(6):716-20.
2001: Matsuda H; Morikawa T; Ninomiya K; Yoshikawa M
Hepatoprotective constituents from zedoariae rhizoma: absolute stereostructures of three new carabrane-type sesquiterpenes, curcumenolactones A, B, and C.
Bioorganic & medicinal chemistry 2001;9(4):909-16.
2001: Matsuda H; Morikawa T; Toguchida I; Park J Y; Harima S; Yoshikawa M
Antioxidant constituents from rhubarb: structural requirements of stilbenes for the activity and structures of two new anthraquinone glucosides.
Bioorganic & medicinal chemistry 2001;9(1):41-50.
2000: Yoshikawa M; Shimoda H; Uemura T; Morikawa T; Kawahara Y; Matsuda H
Alcohol absorption inhibitors from bay leaf (Laurus nobilis): structure-requirements of sesquiterpenes for the activity.
Bioorganic & medicinal chemistry 2000;8(8):2071-7.
2000: Yoshikawa M; Morikawa T; Toguchida I; Harima S; Matsuda H
Medicinal flowers. II. Inhibitors of nitric oxide production and absolute stereostructures of five new germacrane-type sesquiterpenes, kikkanols D, D monoacetate, E, F, and F monoacetate from the flowers of Chrysanthemum indicum L.
Chemical & pharmaceutical bulletin 2000;48(5):651-6.
2000: Matsuda H; Kagerura T; Toguchida I; Ueda H; Morikawa T; Yoshikawa M
Inhibitory effects of sesquiterpenes from bay leaf on nitric oxide production in lipopolysaccharide-activated macrophages: structure requirement and role of heat shock protein induction.
Life sciences 2000;66(22):2151-7.
2000: Matsuda H; Kageura T; Morikawa T; Toguchida I; Harima S; Yoshikawa M
Effects of stilbene constituents from rhubarb on nitric oxide production in lipopolysaccharide-activated macrophages.
Bioorganic & medicinal chemistry letters 2000;10(4):323-7.
1999: Yoshikawa M; Morikawa T; Murakami T; Toguchida I; Harima S; Matsuda H
Medicinal flowers. I. Aldose reductase inhibitors and three new eudesmane-type sesquiterpenes, kikkanols A, B, and C, from the flowers of Chrysanthemum indicum L.
Chemical & pharmaceutical bulletin 1999;47(3):340-5.
1998: Matsuda H; Ninomiya K; Morikawa T; Yoshikawa M
Inhibitory effect and action mechanism of sesquiterpenes from Zedoariae Rhizoma on D-galactosamine/lipopolysaccharide-induced liver injury.
Bioorganic & medicinal chemistry letters 1998;8(4):339-44.
1997: Yoshikawa M; Shimada H; Morikawa T; Yoshizumi S; Matsumura N; Murakami T; Matsuda H; Hori K; Yamahara J
Medicinal foodstuffs. VII. On the saponin constituents with glucose and alcohol absorption-inhibitory activity from a food garnish "Tonburi", the fruit of Japanese Kochia scoparia (L.) Schrad.: structures of scoparianosides A, B, and C.
Chemical & pharmaceutical bulletin 1997;45(8):1300-5.

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