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Keiichirou Morimura

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Kenjiro Tatematsu; Keiichirou Morimura; Shoji Fukushima; Akihiro Koide; Yukio Mori
The enhancing effect of ethanol on the mutagenic activation of N-nitrosomethylbenzylamine by cytochrome P450 2A in the rat oesophagus.
Masashi Takemura; Kayo Yoshida; Keiichirou Morimura
Thoracoscopic resection of thoracic esophageal duplication cyst containing ectopic pancreatic tissue in adult.
Masashi Takemura; Keiichirou Morimura; Kayo Yoshida; Yushi Fujiwara
[Four resected cases with basaloid carcinoma of esophagus--comparison of 5-FU-related enzymes (thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD), orotate phosphoribosyl transferase (OPRT)) between basaloid carcinoma and squamous cell carcinoma].

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2013: Kenjiro Tatematsu; Keiichirou Morimura; Shoji Fukushima; Akihiro Koide; Yukio Mori
The enhancing effect of ethanol on the mutagenic activation of N-nitrosomethylbenzylamine by cytochrome P450 2A in the rat oesophagus.
Mutagenesis 2013;28(2):161-9.
2011: Masashi Takemura; Kayo Yoshida; Keiichirou Morimura
Thoracoscopic resection of thoracic esophageal duplication cyst containing ectopic pancreatic tissue in adult.
Journal of cardiothoracic surgery 2011;6():118.
2010: Masashi Takemura; Keiichirou Morimura; Kayo Yoshida; Yushi Fujiwara
[Four resected cases with basaloid carcinoma of esophagus--comparison of 5-FU-related enzymes (thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD), orotate phosphoribosyl transferase (OPRT)) between basaloid carcinoma and squamous cell carcinoma].
Gan to kagaku ryoho. Cancer & chemotherapy 2010;37(11):2143-6.
2010: Masashi Takemura; Keiichirou Morimura; Kayo Yoshida; Harushi Osugi; Shigeru Lee; Satoru Kishida
[Selection of anticancer drug for poorly-differentiated adenocarcinoma of colorectum from the level of orotate phosphoribosyl transferase and dihydropyrimidine dehydrogenase activities in cancer tissue].
Gan to kagaku ryoho. Cancer & chemotherapy 2010;37(7):1297-301.
2010: Masashi Takemura; Kayo Yoshida; Keiichirou Morimura; Harushi Osugi; Shigeru Lee; Satoru Kishida
[Correlation between clinicopathological factors and enzymatic activity of orotate phosphoribosyl transferase (OPRT), dihydropyrimidine dehydrogenase (DPD) in esophageal cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 2010;37(7):1283-6.
2009: Min Wei; Al-Salmy Hamoud; Takashi Yamaguchi; Anna Kakehashi; Keiichirou Morimura; Kenichiro Doi; Masahiko Kushida; Mitsuaki Kitano; Hideki Wanibuchi; Shoji Fukushima
Potassium bromate enhances N-ethyl-N-hydroxyethylnitrosamine-induced kidney carcinogenesis only at high doses in Wistar rats: indication of the existence of an enhancement threshold.
Toxicologic pathology 2009;37(7):983-91.
2009: Alina Romanenko; Anna Kakehashi; Keiichirou Morimura; Hideki Wanibuchi; Min Wei; Alexander Vozianov; Shoji Fukushima
Urinary bladder carcinogenesis induced by chronic exposure to persistent low-dose ionizing radiation after Chernobyl accident.
Carcinogenesis 2009;30(11):1821-31.
2009: Kenichiro Fukuhara; Harushi Osugi; Shigeru Lee; Keiichirou Morimura; Satoru Kishida; Satoshi Nishizawa; Hiroshi Iwasaki; Ken Gyobu
Remnant gastritis should be evaluated histologically rather than endoscopically.
Hepato-gastroenterology 2009;56(91-92):905-7.
2008: Elsayed I. Salim; Keiichirou Morimura; Ahmed Menesi; Mohammed El-Lity; Shoji Fukushima; Hideki Wanibuchi
Elevated oxidative stress and DNA damage and repair levels in urinary bladder carcinomas associated with schistosomiasis.
International journal of cancer. Journal international du cancer 2008;123(3):601-8.
2008: Kenichiro Fukuhara; Harushi Osugi; Masashi Takemura; Shigeru Lee; Keiichirou Morimura; Satoru Kishida; Satoshi Nishizawa; Hiroshi Iwasaki; Ken Gyobu
Helicobacter pylori induces gastritis and oxidative stress after distal gastrectomy.
Hepato-gastroenterology 2008;55(85):1484-6.
2008: Sung-Hoon Ahn; Yatrik M Shah; Junko Inoue; Keiichirou Morimura; Insook Kim; Sunhee Yim; Gilles Lambert; Reiko Kurotani; Kunio Nagashima; Frank J Gonzalez; Yusuke Inoue
Hepatocyte nuclear factor 4alpha in the intestinal epithelial cells protects against inflammatory bowel disease.
Inflammatory bowel diseases 2008;14(7):908-20.
2008: Yatrik M Shah; Shinji Ito; Keiichirou Morimura; Chi Chen; Sun Hee Yim; Volker H Haase; Frank J Gonzalez
Hypoxia-inducible factor augments experimental colitis through an MIF-dependent inflammatory signaling cascade.
Gastroenterology 2008;134(7):2036-48, 2048.e1-3.
2008: Jin Seok Kang; Hideki Wanibuchi; Keiichirou Morimura; Rawiwan Wongpoomchai; Yaowares Chusiri; Frank J Gonzalez; Shoji Fukushima
Role of CYP2E1 in thioacetamide-induced mouse hepatotoxicity.
Toxicology and applied pharmacology 2008;228(3):295-300.
2008: Takshi Murai; Satoru Mori; Jin Seok Kang; Keiichirou Morimura; Hideki Wanibuchi; Yukari Totsuka; Shoji Fukushima
Evidence of a threshold-effect for 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline liver carcinogenicity in F344/DuCrj rats.
Toxicologic pathology 2008;36(3):472-7.
2008: Kenichiro Fukuhara; Harushi Osugi; Masashi Takemura; Shigeru Lee; Keiichirou Morimura; Takayuki Nishikawa; Hiroshi Iwasaki; Shoji Fukushima; Shigefumi Suehiro
Expression of 8-hydroxydeoxyguanosine in the gastric remnant after distal gastrectomy.
Hepato-gastroenterology 2008;55(82-83):508-11.
2008: Chi Chen; Yatrik M Shah; Keiichirou Morimura; Kristopher W Krausz; Makoto Miyazaki; Terrilyn A Richardson; Edward T Morgan; James M Ntambi; Jeffrey R Idle; Frank J Gonzalez
Metabolomics reveals that hepatic stearoyl-CoA desaturase 1 downregulation exacerbates inflammation and acute colitis.
Cell metabolism 2008;7(2):135-47.
2007: Jin Seok Kang; Hideki Wanibuchi; Keiichirou Morimura; Frank J Gonzalez; Shoji Fukushima
Role of CYP2E1 in diethylnitrosamine-induced hepatocarcinogenesis in vivo.
Cancer research 2007;67(23):11141-6.
2007: Holly E Hollingshead; Keiichirou Morimura; Masahiro Adachi; Mary J. Kennett; Andrew N Billin; Timothy M Willson; Frank J Gonzalez; Jeffrey M Peters
PPARbeta/delta protects against experimental colitis through a ligand-independent mechanism.
Digestive diseases and sciences 2007;52(11):2912-9.
2007: Anna Kakehashi; Hideki Wanibuchi; Keiichirou Morimura; Min Wei; Dai Nakae; Tsuyoshi Arai; Osamu Minowa; Tetsuo Noda; Susumu Nishimura; Shoji Fukushima
Carcinogenicity of dimethylarsinic acid in Ogg1-deficient mice.
Cancer science 2007;98(6):803-14.
2007: Yatrik M Shah; Keiichirou Morimura; Qian Yang; Tomotaka Tanabe; Mitsuhiro Takagi; Frank J Gonzalez
Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation.
Molecular and cellular biology 2007;27(12):4238-47.
2007: Minori Koshiji; Kensuke Kumamoto; Keiichirou Morimura; Yasufumi Utsumi; Michiko Aizawa; Masami Hoshino; Shinji Ohki; Seiichi Takenoshita; Max Costa; Thérèse Commes; David Piquemal; Curtis-C Harris; Kam-Meng Tchou-Wong
Correlation of N-myc downstream-regulated gene 1 expression with clinical outcomes of colorectal cancer patients of different race/ethnicity.
World journal of gastroenterology : WJG 2007;13(20):2803-10.
2007: Insook Kim; Keiichirou Morimura; Yatrik M Shah; Qian Yang; Jerrold M Ward; Frank J Gonzalez
Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice.
Carcinogenesis 2007;28(5):940-6.
2007: Jin Seok Kang; Hideki Wanibuchi; Takashi Murai; Keiichirou Morimura; Anna Kakehashi; Shoji Fukushima
Analysis of gene expression in different stages of MeIQx-induced rat hepatocarcinogenesis.
Oncology reports 2007;17(4):747-52.
2007: Yatrik M Shah; Xiaochao Ma; Keiichirou Morimura; Insook Kim; Frank J Gonzalez
Pregnane X receptor activation ameliorates DSS-induced inflammatory bowel disease via inhibition of NF-kappaB target gene expression.
American journal of physiology. Gastrointestinal and liver physiology 2007;292(4):G1114-22.
2007: Shuji Iwai; Takashi Murai; Susumu Makino; Wei Min; Keiichirou Morimura; Satoru Mori; Atsushi Hagihara; Shuichi Seki; Shoji Fukushima
High sensitivity of fatty liver Shionogi (FLS) mice to diethylnitrosamine hepatocarcinogenesis: comparison to C3H and C57 mice.
Cancer letters 2007;246(1-2):115-21.
2007: Yatrik M Shah; Keiichirou Morimura; Frank J Gonzalez
Expression of peroxisome proliferator-activated receptor-gamma in macrophage suppresses experimentally induced colitis.
American journal of physiology. Gastrointestinal and liver physiology 2007;292(2):G657-66.
2006: Alina Romanenko; Keiichirou Morimura; Anna Kakehashi; Hideki Wanibuchi; Satoru Takahashi; Wadim K Zaparin; Wladimir I Vinnichenko; Alexander Vozianov; Shoji Fukushima
Upregulation of fibroblast growth factor receptor 3 and epidermal growth factor receptors, in association with Raf-1, in urothelial dysplasia and carcinoma in situ after the Chernobyl accident.
Cancer science 2006;97(11):1168-74.
2006: Rawiwan Puatanachokchai; Keiichirou Morimura; Hideki Wanibuchi; Mayuko Oka; Anna Kakehashi; Fukui Mitsuru; Shuji Yamaguchi; Yoshihiko Funae; Shoji Fukushima
Alpha-benzene hexachloride exerts hormesis in preneoplastic lesion formation of rat hepatocarcinogenesis with the possible role for hepatic detoxifying enzymes.
Cancer letters 2006;240(1):102-13.
2006: M Adachi; Reiko Kurotani; Keiichirou Morimura; Yatrik M Shah; M Sanford; Blair B Madison; Deborah L Gumucio; H E Marin; Jeffrey M Peters; Howard A Young; Frank J Gonzalez
Peroxisome proliferator activated receptor gamma in colonic epithelial cells protects against experimental inflammatory bowel disease.
Gut 2006;55(8):1104-13.
2006: Shoji Fukushima; Hideki Wanibuchi; Min Wei; Keiichirou Morimura
[Development of invasive urinary bladder carcinomas].
Hinyokika kiyo. Acta urologica Japonica 2006;52(6):451-5.
2006: Mitsuaki Kitano; Jutaro Wada; Yutaka Ariki; Masanori Kato; Hideki Wanibuchi; Keiichirou Morimura; Takayoshi Hidaka; Kazunori Hosoe; Shoji Fukushima
Possible tumor development from double positive foci for TGF-alpha and GST-P observed in early stages on rat hepatocarcinogenesis.
Cancer science 2006;97(6):478-83.
2006: Jin Seok Kang; Hideki Wanibuchi; Keiichirou Morimura; Yukari Totsuka; Isao Yoshimura; Shoji Fukushima
Existence of a no effect level for MeIQx hepatocarcinogenicity on a background of thioacetamide-induced liver damage in rats.
Cancer science 2006;97(6):453-8.
2006: Keiichirou Morimura; Connie Cheung; Jerrold M Ward; Janardan K Reddy; Frank J Gonzalez
Differential susceptibility of mice humanized for peroxisome proliferator-activated receptor alpha to Wy-14,643-induced liver tumorigenesis.
Carcinogenesis 2006;27(5):1074-80.
2006: Motome Nishikawa-Ogawa; Hideki Wanibuchi; Keiichirou Morimura; Anna Kakehashi; Takayuki Nishikawa; Shuji Hayashi; Yoshihisa Yano; Shoji Fukushima
N-acetylcysteine and S-methylcysteine inhibit MeIQx rat hepatocarcinogenesis in the post-initiation stage.
Carcinogenesis 2006;27(5):982-8.
2006: Rawiwan Puatanachokchai; Masakazu Kakuni; Hideki Wanibuchi; Anna Kakehashi; Jin Seok Kang; Elsayed I. Salim; Keiichirou Morimura; Seiko Tamano; Glenn T Merlino; Shoji Fukushima
Lack of promoting effects of phenobarbital at low dose on diethylnitrosamine-induced hepatocarcinogenesis in TGF-alpha transgenic mice.
Asian Pacific journal of cancer prevention : APJCP 2006;7(2):274-8.
2006: Jin Seok Kang; Keiichirou Morimura; Chitose Toda; Hideki Wanibuchi; Min Wei; Nakao Kojima; Shoji Fukushima
Testicular toxicity of DEHP, but not DEHA, is elevated under conditions of thioacetamide-induced liver damage.
Reproductive toxicology (Elmsford, N.Y.) 2006;21(3):253-9.
2006: Min Wei; Taka-Aki Hori; Toshio Ichihara; Hideki Wanibuchi; Keiichirou Morimura; Jin Seok Kang; Rawiwan Puatanachokchai; Shoji Fukushima
Existence of no-observed effect levels for 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline on hepatic preneoplastic lesion development in BN rats.
Cancer letters 2006;231(2):304-8.
2006: Masahiko Kushida; Sigetoshi Aiso; Keiichirou Morimura; Min Wei; Hideki Wanibuchi; Kasuke Nagano; Shoji Fukushima
Absence of beta-catenin alteration in hepatic tumors induced by p-nitroanisole in Crj:BDF1 mice.
Toxicologic pathology 2006;34(3):237-42.
2006: Hideki Wanibuchi; Min Wei; M Rezaul Karim; Keiichirou Morimura; Kenichiro Doi; Anna Kakehashi; Shoji Fukushima
Existence of no hepatocarcinogenic effect levels of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline with or without coadministration with ethanol.
Toxicologic pathology 2006;34(3):232-6.
2006: Hideki Wanibuchi; Min Wei; Elsayed I. Salim; Anna Kakehashi; Keiichirou Morimura; Katsuichi Sudo; Shoji Fukushima
Inhibition of rat urinary bladder carcinogenesis by the antiangiogenic drug TNP-470.
Asian Pacific journal of cancer prevention : APJCP 2006;7(1):101-7.
2006: Alina Romanenko; Keiichirou Morimura; Anna Kakehashi; Hideki Wanibuchi; Alexander Vozianov; Shoji Fukushima
Aberrant expression of E-cadherin and beta-catenin in association with transforming growth factor-beta1 in urinary bladder lesions in humans after the Chernobyl accident.
Cancer science 2006;97(1):45-50.
2005: Masahiko Kushida; Hideki Wanibuchi; Keiichirou Morimura; Anna Kakehashi; Jin Seok Kang; Rawiwan Puatanachokchai; Min Wei; Yoshihiko Funae; Shoji Fukushima
Dose-dependence of promotion of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline-induced rat hepatocarcinogenesis by ethanol: evidence for a threshold.
Cancer science 2005;96(11):747-57.
2005: Shoji Fukushima; Anna Kakehashi; Rawiwan Puatanachokchai; Masahiko Kushida; Hideki Wanibuchi; Keiichirou Morimura
Hormesis and dose-response-mediated mechanisms in carcinogenesis: evidence for a threshold in carcinogenicity of non-genotoxic carcinogens.
Carcinogenesis 2005;26(11):1835-45.
2005: Masahiko Kushida; Tokuo Sukata; Satoshi Uwagawa; Keisuke Ozaki; Anna Kakehashi; Hideki Wanibuchi; Keiichirou Morimura; Yasuyoshi Okuno; Shoji Fukushima
Low dose DDT inhibition of hepatocarcinogenesis initiated by diethylnitrosamine in male rats: possible mechanisms.
Toxicology and applied pharmacology 2005;208(3):285-94.
2005: Shoji Fukushima; Keiichirou Morimura; Hideki Wanibuchi; Anna Kakehashi; Elsayed I. Salim
Current and emerging challenges in toxicopathology: carcinogenic threshold of phenobarbital and proof of arsenic carcinogenicity using rat medium-term bioassays for carcinogens.
Toxicology and applied pharmacology 2005;207(2 Suppl):225-9.
2005: Kenichiro Doi; Hideki Wanibuchi; Elsayed I. Salim; Keiichirou Morimura; Anna Kakehashi; Shinzoh Kudoh; Kazuto Hirata; Junichi Yoshikawa; Shoji Fukushima
Lack of large intestinal carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine at low doses in rats initiated with azoxymethane.
International journal of cancer. Journal international du cancer 2005;115(6):870-8.
2005: Shoji Fukushima; Hideki Wanibuchi; Keiichirou Morimura; Dai Nakae; Hiroyuki Tsuda; Katsumi Imaida; Tomoyuki Shirai; Masae Tatematsu; Tetsuya Tsukamoto; Masao Hirose; Fumio Furukawa
Lack of potential of low dose N-nitrosodimethylamine to induce preneoplastic lesions, glutathione S-transferase placental form-positive foci, in rat liver.
Cancer letters 2005;222(1):11-5.
2005: Jin Seok Kang; Hideki Wanibuchi; Keiichirou Morimura; Rawiwan Puatanachokchai; Elsayed I. Salim; Atsushi Hagihara; Shuichi Seki; Shoji Fukushima
Enhancement by estradiol 3-benzoate in thioacetamide-induced liver cirrhosis of rats.
Toxicological sciences : an official journal of the Society of Toxicology 2005;85(1):720-6.
2005: Min Wei; Keiichirou Morimura; Hideki Wanibuchi; Jun Shen; Elsayed I. Salim; Masaharu Moku; Katsuo Hakoi; Shoji Fukushima
JTE-522, a selective cyclooxygenase-2 inhibitor, inhibits induction but not growth and invasion of 1,2-dimethylhydrazine-induced tubular adenocarcinomas of colon in rats.
International journal of cancer. Journal international du cancer 2005;113(3):354-8.
2005: Keiichirou Morimura; Jin Seok Kang; Min Wei; Hideki Wanibuchi; Hiroyuki Tsuda; Shoji Fukushima
Lack of urinary bladder carcinogenicity of sodium L-ascorbate in human c-Ha-ras proto-oncogene transgenic rats.
Toxicologic pathology 2005;33(7):764-7.
2005: Jin Seok Kang; Keiichirou Morimura; Elsayed I. Salim; Hideki Wanibuchi; Shuji Yamaguchi; Shoji Fukushima
Persistence of liver cirrhosis in association with proliferation of nonparenchymal cells and altered location of alpha-smooth muscle actin-positive cells.
Toxicologic pathology 2005;33(3):329-35.
2004: Toshio Ichihara; Hideki Wanibuchi; Yukari Totsuka; Keiichirou Morimura; Min Wei; Dai Nakae; Shoji Fukushima
Induction of DNA-adducts and increase of 8-hydroxy-2-deoxyguanosine, but no development of preneoplastic lesions in offspring liver with transplacental and trans-breast milk exposure to 2-amino-3,8-dimethylimidazo [4,5-f ]quinoxaline (MeIQx) in rats.
Cancer science 2004;95(12):943-8.
2004: Yushi Fujiwara; Harushi Osugi; Keiichirou Morimura; Masashi Takemura; Shigeru Lee; Kazuhiro Hirohashi; Shoji Fukushima; Shigefumi Suehiro
Suppressive effect of CPT-11 on rat esophageal tumorigenesis induced by N-nitrosomethylbenzylamine.
Oncology reports 2004;12(6):1169-76.
2004: Elsayed I. Salim; Masahiro Kaneko; Hideki Wanibuchi; Keiichirou Morimura; Shoji Fukushima
Lack of carcinogenicity of enzymatically modified isoquercitrin in F344/DuCrj rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2004;42(12):1949-69.
2004: Tokuo Sukata; Satoshi Uwagawa; Keisuke Ozaki; Kayo Sumida; Kaoru Kikuchi; Masahiko Kushida; Koichi Saito; Keiichirou Morimura; Kenji Oeda; Yasuyoshi Okuno; Nobuyoshi Mikami; Shoji Fukushima
alpha(2)-Macroglobulin: a novel cytochemical marker characterizing preneoplastic and neoplastic rat liver lesions negative for hitherto established cytochemical markers.
The American journal of pathology 2004;165(5):1479-88.
2004: Manabu Hoshi; Keiichirou Morimura; Hideki Wanibuchi; Min Wei; Eriko Okochi; Toshikazu Ushijima; Kunio Takaoka; Shoji Fukushima
No-observed effect levels for carcinogenicity and for in vivo mutagenicity of a genotoxic carcinogen.
Toxicological sciences : an official journal of the Society of Toxicology 2004;81(2):273-9.
2004: Kenichiro Fukuhara; Harushi Osugi; Nobuyasu Takada; Masashi Takemura; Shigeru Lee; Keiichirou Morimura; Shinichi Taguchi; Masahiro Kaneko; Yoshinori Tanaka; Yushi Fujiwara; Satoshi Nishizawa; Shoji Fukushima; Hiroaki Kinoshita
Effect of H. pylori on COX-2 expression in gastric remnant after distal gastrectomy.
Hepato-gastroenterology 2004;51(59):1515-8.
2004: Hideki Wanibuchi; Elsayed I. Salim; Anna Kakehashi; Jun Shen; Min Wei; Keiichirou Morimura; Kaoru Yoshida; Koichi Kuroda; Ginji Endo; Shoji Fukushima
Understanding arsenic carcinogenicity by the use of animal models.
Toxicology and applied pharmacology 2004;198(3):366-76.
2004: Shoji Fukushima; Hideki Wanibuchi; Keiichirou Morimura; Shuji Iwai; Dai Nakae; Hideki Kishida; Hiroyuki Tsuda; N Uehara; Katsumi Imaida; Tomoyuki Shirai; Masae Tatematsu; Tetsuya Tsukamoto; Masao Hirose; Fumio Furukawa
Existence of a threshold for induction of aberrant crypt foci in the rat colon with low doses of 2-amino-1-methyl-6-phenolimidazo[4,5-b]pyridine.
Toxicological sciences : an official journal of the Society of Toxicology 2004;80(1):109-14.
2004: Yoshinori Tanaka; Harushi Osugi; Keiichirou Morimura; Masashi Takemura; Masakatsu Ueno; Masahiro Kaneko; Shoji Fukushima; Hiroaki Kinoshita
Effect of duodenogastric reflux on N-methyl-N'-nitro-N-nitrosoguanidine-induced glandular stomach tumorigenesis in Helicobacter pylori-infected Mongolian gerbils.
Oncology reports 2004;11(5):965-71.
2004: Keiichirou Morimura; Alina Romanenko; Wei Min; Elsayed I. Salim; Anna Kakehashi; Hideki Wanibuchi; Alexander Vozianov; Shoji Fukushima
Possible distinct molecular carcinogenic pathways for bladder cancer in Ukraine, before and after the Chernobyl disaster.
Oncology reports 2004;11(4):881-6.
2004: Min Wei; Hideki Wanibuchi; Keiichirou Morimura; Elsayed I. Salim; Masaharu Moku; Kenichiro Doi; Makoto Mitsuhashi; Chikayoshi Masuda; Jun Shen; Anna Kakehashi; Shoji Fukushima
Lack of preventive efficacy of FK228, a histone deacetylase inhibitor, against N-butyl-N-(4-hydroxybutyl) nitrosamine-induced urinary bladder carcinogenesis in p53+/- and p53+/+ mice.
Anticancer research 2004;24(2B):785-90.
2003: Jun Shen; Hideki Wanibuchi; Elsayed I. Salim; Min Wei; Kenichiro Doi; Kaoru Yoshida; Ginji Endo; Keiichirou Morimura; Shoji Fukushima
Induction of glutathione S-transferase placental form positive foci in liver and epithelial hyperplasia in urinary bladder, but no tumor development in male Fischer 344 rats treated with monomethylarsonic acid for 104 weeks.
Toxicology and applied pharmacology 2003;193(3):335-45.
2003: Min Wei; Keiichirou Morimura; Hideki Wanibuchi; Jun Shen; Kenichiro Doi; Makoto Mitsuhashi; Masaharu Moku; Elsayed I. Salim; Shoji Fukushima
Chemopreventive effect of JTE-522, a selective cyclooxygenase-2 inhibitor, on 1, 2-dimethylhydrazine-induced rat colon carcinogenesis.
Cancer letters 2003;202(1):11-6.
2003: Makoto Mitsuhashi; Hideki Wanibuchi; Keiichirou Morimura; Ken'ichiro Doi; Min Wei; Seiji Wada; Tatsuya Nakatani; Shoji Fukushima
Significance of overexpression of metallothionein in mouse urinary bladder focal lesions induced by treatment with N-butyl-N-(4-hydroxybutyl)-nitrosamine.
Cancer science 2003;94(12):1052-8.
2003: Anna Kakehashi; Hideki Wanibuchi; Keiichirou Morimura; Min Wei; Jun Shen; Susumu Imaoka; Yoshihiko Funae; Shoji Fukushima
Phenobarbital at low dose exerts hormesis in rat hepatocarcinogenesis by reducing oxidative DNA damage, altering cell proliferation, apoptosis and gene expression.
Carcinogenesis 2003;24(8):1389-99.
2003: Takayuki Nishikawa; Elsayed I. Salim; Keiichirou Morimura; Masahiro Kaneko; Motome Ogawa; Anna Kakehashi; Harushi Osugi; Hiroaki Kinoshita; Shoji Fukushima
High susceptibility of p53 knockout mice to esophageal and urinary bladder carcinogenesis induced by N, N-dibutylnitrosamine.
Cancer letters 2003;194(1):45-54.
2003: Alina Romanenko; Keiichirou Morimura; Hideki Wanibuchi; Min Wei; Wadim K Zaparin; Wladimir I Vinnichenko; Anna Kakehashi; Alexander Vozianov; Shoji Fukushima
Urinary bladder lesions induced by persistent chronic low-dose ionizing radiation.
Cancer science 2003;94(4):328-33.
2003: M Rezaul Karim; Hideki Wanibuchi; Min Wei; Keiichirou Morimura; Elsayed I. Salim; Shoji Fukushima
Enhancing risk of ethanol on MeIQx-induced rat hepatocarcinogenesis is accompanied with increased levels of cellular proliferation and oxidative stress.
Cancer letters 2003;192(1):37-47.
2003: Noritaka Seike; Hideki Wanibuchi; Keiichirou Morimura; Min Wei; Takayuki Nishikawa; Kazuto Hirata; Junichi Yoshikawa; Shoji Fukushima
Enhancement of lung carcinogenesis by nonylphenol and genistein in a F344 rat multiorgan carcinogenesis model.
Cancer letters 2003;192(1):25-36.
2003: Shoji Fukushima; Hideki Wanibuchi; Keiichirou Morimura; Min Wei; Dai Nakae; Yoichi Konishi; Hiroyuki Tsuda; Nobuo Takasuka; Katsumi Imaida; Tomoyuki Shirai; Masae Tatematsu; Tetsuya Tsukamoto; Masao Hirose; Fumio Furukawa
Lack of initiation activity in rat liver of low doses of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline.
Cancer letters 2003;191(1):35-40.
2003: Elsayed I. Salim; Hideki Wanibuchi; Keiichirou Morimura; Min Wei; Makoto Mitsuhashi; Kaoru Yoshida; Ginji Endo; Shoji Fukushima
Carcinogenicity of dimethylarsinic acid in p53 heterozygous knockout and wild-type C57BL/6J mice.
Carcinogenesis 2003;24(2):335-42.
2003: Makoto Mitsuhashi; Hideki Wanibuchi; Min Wei; Ken'ichro Doi; Keiichirou Morimura; Chikayoshi Masuda; Seiji Wada; Tatsuya Nakatani; Tadao Kakizoe; Shoji Fukushima
No inhibition of urinary bladder carcinogenesis in rats with intravesical instillation of alpha-galactosylceramide.
Asian Pacific journal of cancer prevention : APJCP 2003;4(1):45-50.
2003: Hiroyuki Tsuda; Shoji Fukushima; Hideki Wanibuchi; Keiichirou Morimura; Dai Nakae; Katsumi Imaida; Masae Tatematsu; Masao Hirose; Keiji Wakabayashi; Malcolm Moore
Value of GST-P positive preneoplastic hepatic foci in dose-response studies of hepatocarcinogenesis: evidence for practical thresholds with both genotoxic and nongenotoxic carcinogens. A review of recent work.
Toxicologic pathology 2003;31(1):80-6.
2002: Harushi Osugi; Masashi Takemura; Keiichirou Morimura; Masahiro Kaneko; Masayuki Higashino; Nobuyasu Takada; Sigeru Lee; Hiroaki Kinoshita
Clinicopathologic and immunohistochemical features of surgically resected small cell carcinoma of the esophagus.
Oncology reports 2002;9(6):1245-9.
2002: Shoji Fukushima; Hideki Wanibuchi; Keiichirou Morimura; Min Wei; Dai Nakae; Yoichi Konishi; Hiroyuki Tsuda; Nobuaki Uehara; Katsumi Imaida; Tomoyuki Shirai; Masae Tatematsu; Tetsuya Tsukamoto; Masao Hirose; Fumio Furukawa; Keiji Wakabayashi; Yukari Totsuka
Lack of a dose-response relationship for carcinogenicity in the rat liver with low doses of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline or N-nitrosodiethylamine.
Japanese journal of cancer research : Gann 2002;93(10):1076-82.
2002: Masahiro Kaneko; Keiichirou Morimura; Takayuki Nishikawa; Hideki Wanibuchi; Nobuyasu Takada; Harushi Osugi; Hiroaki Kinoshita; Shoji Fukushima
Different genetic alterations in rat forestomach tumors induced by genotoxic and non-genotoxic carcinogens.
Carcinogenesis 2002;23(10):1729-35.
2002: Elsayed I. Salim; Hideki Wanibuchi; Keiichirou Morimura; Takashi Murai; Susumu Makino; Taisei Nomura; Shoji Fukushima
Induction of tumors in the colon and liver of the immunodeficient (SCID) mouse by 2-amino-3-methylimidazo[4,5-f ]quinoline (IQ)-modulation by long-chain fatty acids.
Carcinogenesis 2002;23(9):1519-29.
2002: Alina Romanenko; Keiichirou Morimura; Min Wei; Wadim K Zaparin; Alexander Vozianov; Shoji Fukushima
DNA damage repair in bladder urothelium after the Chernobyl accident in Ukraine.
The Journal of urology 2002;168(3):973-7.
2002: Harushi Osugi; Keiichirou Morimura; Eiki Okuda; Masashi Takemura; Masayuki Higashino; Nobuyasu Takada; Hiroaki Kinoshita
p53 null mutations detected by a p53 yeast functional assay predict a poor outcome in young esophageal carcinoma patients.
International journal of oncology 2002;21(3):637-41.
2002: Masahiro Kaneko; Keiichirou Morimura; Takayuki Nishikawa; Hideki Wanibuchi; Harushi Osugi; Hiroaki Kinoshita; Akihiro Koide; Yukio Mori; Shoji Fukishima
Weak enhancing effects of simultaneous ethanol administration on chemically induced rat esophageal tumorigenesis.
Oncology reports 2002;9(5):1069-73.
2002: Min Wei; Hideki Wanibuchi; Keiichirou Morimura; Shuji Iwai; Kaoru Yoshida; Ginji Endo; Dai Nakae; Shoji Fukushima
Carcinogenicity of dimethylarsinic acid in male F344 rats and genetic alterations in induced urinary bladder tumors.
Carcinogenesis 2002;23(8):1387-97.
2002: Takayuki Nishikawa; Hideki Wanibuchi; Motome Ogawa; Anna Kakehashi; Keiichirou Morimura; Toyoko Hiroi; Yoshihiko Funae; Hideki Kishida; Dai Nakae; Shoji Fukushima
Promoting effects of monomethylarsonic acid, dimethylarsinic acid and trimethylarsine oxide on induction of rat liver preneoplastic glutathione S-transferase placental form positive foci: a possible reactive oxygen species mechanism.
International journal of cancer. Journal international du cancer 2002;100(2):136-9.
2002: Takashi Kuramoto; Keiichirou Morimura; Satoshi Yamashita; Eriko Okochi; Naoko Watanabe; Tsutomu Ohta; Misao Ohki; Shoji Fukushima; Takashi Sugimura; Toshikazu Ushijima
Etiology-specific gene expression profiles in rat mammary carcinomas.
Cancer research 2002;62(13):3592-7.
2002: Shuji Iwai; Rezaul Karim; Mitsuaki Kitano; Tokuo Sukata; Wei Min; Keiichirou Morimura; Hideki Wanibuchi; Shuichi Seki; Shoji Fukushima
Role of oxidative DNA damage caused by carbon tetrachloride-induced liver injury -- enhancement of MeIQ-induced glutathione S-transferase placental form-positive foci in rats.
Cancer letters 2002;179(1):15-24.
2002: Yukio Mori; Akihiro Koide; Yoshinori Kobayashi; Keiichirou Morimura; Masahiro Kaneko; Shoji Fukushima
Effect of ethanol treatment on metabolic activation and detoxification of esophagus carcinogenic N-nitrosamines in rat liver.
Mutagenesis 2002;17(3):251-6.
2002: Masakazu Kakuni; Keiichirou Morimura; Hideki Wanibuchi; Motome Ogawa; Wei Min; Shuji Hayashi; Shoji Fukushima
Food restriction inhibits the growth of intestinal polyps in multiple intestinal neoplasia mouse.
Japanese journal of cancer research : Gann 2002;93(3):236-41.
2002: Anna Kakehashi; Hideki Wanibuchi; Susumu Imaoka; Motome Ogawa; Chikayoshi Masuda; Keiichirou Morimura; Yoshihiko Funae; Shoji Fukushima
Formation of 8-hydroxydeoxyguanosine and cell-cycle arrest in the rat liver via generation of oxidative stress by phenobarbital: association with expression profiles of p21(WAF1/Cip1), cyclin D1 and Ogg1.
Carcinogenesis 2002;23(2):341-9.
2002: Noritaka Seike; Hideki Wanibuchi; Keiichirou Morimura; Takayuki Nishikawa; Hideki Kishida; Dai Nakae; Kazuto Hirata; Shoji Fukushima
Lack of promoting effect due to oral administration of dimethylarsinic acid on rat lung carcinogenesis initiated with N-bis(2-hydroxypropyl)nitrosamine.
Cancer letters 2002;175(2):113-9.
2002: Rezaul Karim; Shuji Iwai; Keiichirou Morimura; Hideki Wanibuchi; Reiko Tanaka; Shunyo Matsunaga; Akira Yoshitake; Shoji Fukushima
Lack of modification of rat hepatocarcinogenesis by fernane-type triterpenoids, isolated from a Euphorbia genus.
Teratogenesis, carcinogenesis, and mutagenesis 2002;22(4):293-9.
2001: H Gen; Shigeo Yamamoto; Keiichirou Morimura; Wei Min; Makoto Mitsuhashi; Takashi Murai; Satoru Mori; M Hosono; T Oohara; Susumu Makino; Hideki Wanibuchi; Shoji Fukushima
p53 and H-ras mutations and microsatellite instability in renal pelvic carcinomas of NON / Shi mice treated with N-butyl-N-(4-hydroxybutyl)-nitrosamine: different genetic alteration from urinary bladder carcinoma.
Japanese journal of cancer research : Gann 2001;92(12):1278-83.
2001: Alina Romanenko; Alexander Vozianov; Keiichirou Morimura; S Fukushima
Correspondence re: W. Paile's letter to the editor. Cancer Res., 60: 1146, 2000.
Cancer research 2001;61(18):6964-5.
2001: Eiki Okuda; Harushi Osugi; Keiichirou Morimura; Nobuyasu Takada; Masashi Takemura; S Fukushima; Masayuki Higashino; Hiroaki Kinoshita
Detection of p53 gene mutations in human esophageal squamous cell carcinomas using a p53 yeast functional assay: possible difference in esophageal carcinogenesis between the young and the elderly group.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3):600-6.
2001: Keiichirou Morimura; T Hori; Masahiro Kaneko; Takayuki Nishikawa; A Nishikawa; Hideki Wanibuchi; Nobuyasu Takada; Harushi Osugi; Shoji Fukushima
Promotion of chemically induced rat esophageal tumorigenesis with post-initiation ethanol modification.
Teratogenesis, carcinogenesis, and mutagenesis 2001;21(4):295-301.
2001: Shuji Iwai; Min Wei; Keiichirou Morimura; Hideki Wanibuchi; R Tanaka; Shunyo Matsunaga; A Yoshitake; Shuichi Seki; Shoji Fukushima
Possible prevention by abieslactone of development of diethylnitrosamine-initiated GST-P positive foci in the rat liver.
Teratogenesis, carcinogenesis, and mutagenesis 2001;21(3):223-9.
2000: Min Wei; Hideki Wanibuchi; Shigeo Yamamoto; Shuji Iwai; Keiichirou Morimura; Taisei Nomura; R Takayama; Shoji Fukushima
Chemopreventive effects of S-methylcysteine on rat hepatocarcinogenesis induced by concurrent administration of sodium nitrite and morpholine.
Cancer letters 2000;161(1):97-103.
2000: Alina Romanenko; Keiichirou Morimura; Hideki Wanibuchi; Elsayed I. Salim; Anna Kakehashi; M Kaneko; Alexander Vozianov; Shoji Fukushima
Increased oxidative stress with gene alteration in urinary bladder urothelium after the Chernobyl accident.
International journal of cancer. Journal international du cancer 2000;86(6):790-8.
2000: T Morikawa; Hideki Wanibuchi; Keiichirou Morimura; Motome Ogawa; Shoji Fukushima
Promotion of skin carcinogenesis by dimethylarsinic acid in keratin (K6)/ODC transgenic mice.
Japanese journal of cancer research : Gann 2000;91(6):579-81.
2000: Elsayed I. Salim; Hideki Wanibuchi; Keiichirou Morimura; S Kim; Yoshihisa Yano; Shigeo Yamamoto; Shoji Fukushima
Inhibitory effects of 1,3-diaminopropane, an ornithine decarboxylase inhibitor, on rat two-stage urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Carcinogenesis 2000;21(2):195-203.
1999: TX Chen; Hideki Wanibuchi; Min Wei; Keiichirou Morimura; Shigeo Yamamoto; Shuji Hayashi; Shoji Fukushima
Concentration dependent promoting effects of sodium L-ascorbate with the same total dose in a rat two-stage urinary bladder carcinogenesis.
Cancer letters 1999;146(1):67-71.
1999: Shigeo Yamamoto; Alina Romanenko; Min Wei; Chikayoshi Masuda; Wadim K Zaparin; Wladimir I Vinnichenko; Alexander Vozianov; Chyi-Chia Richard Lee; Keiichirou Morimura; Hideki Wanibuchi; M Tada; Shoji Fukushima
Specific p53 gene mutations in urinary bladder epithelium after the Chernobyl accident.
Cancer research 1999;59(15):3606-9.
1999: Keiichirou Morimura; Elsayed I. Salim; Shigeo Yamamoto; Hideki Wanibuchi; Shoji Fukushima
Dose-dependent induction of aberrant crypt foci in the colons but no neoplastic lesions in the livers of heterozygous p53-deficient mice treated with low dose 2-amino-3-methylimidazo [4,5-f]quinoline.
Cancer letters 1999;138(1-2):81-5.
1999: Keiichirou Morimura; Shigeo Yamamoto; Takashi Murai; Satoru Mori; TX Chen; Hideki Wanibuchi; Shoji Fukushima
LOH and mutational analysis of p53 alleles in mouse urinary bladder carcinomas induced by N-butyl-N-(4-hydroxybutyl) nitrosamine.
Carcinogenesis 1999;20(4):715-8.
1997: Elsayed I. Salim; Hideki Wanibuchi; T Taniyama; Yoshihisa Yano; Keiichirou Morimura; Shigeo Yamamoto; Shuzo Otani; Yoshiki Nishizawa; Hirotoshi Morii; Shoji Fukushima
Inhibition of development of N,N'-dimethylhydrazine-induced rat colonic aberrant crypt foci by pre, post and simultaneous treatments with 24R,25-dihydroxyvitamin D3.
Japanese journal of cancer research : Gann 1997;88(11):1052-62.
1997: Shigeo Yamamoto; T Chen; Takashi Murai; Satoru Mori; Keiichirou Morimura; T Oohara; Susumu Makino; Masae Tatematsu; Hideki Wanibuchi; Shoji Fukushima
Genetic instability and p53 mutations in metastatic foci of mouse urinary bladder carcinomas induced by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Carcinogenesis 1997;18(10):1877-82.
1997: Toshikazu Ushijima; Keiichirou Morimura; Y Hosoya; H Okonogi; Masae Tatematsu; Takashi Sugimura; M Nagao
Establishment of methylation-sensitive-representational difference analysis and isolation of hypo- and hypermethylated genomic fragments in mouse liver tumors.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2284-9.
1995: Keiichirou Morimura; Shigefumi Suehiro; Toshihiko Shibata; H Minamimura; Koji Hattori; Hiroaki Kinoshita
[A case of massive air embolism during cardiopulmonary bypass].
[Zasshi] [Journal]. Nihon Kyōbu Geka Gakkai 1995;43(7):1059-62.