FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Hans Morreau

Research Profile

Disorders

Physiology

Procedures

Chemicals & Drugs

Concepts & Ideas

Neoplasm Staging

Genes & Molecular Sequences

Single Nucleotide Polymorphism

Co-author Network

Publications

TOP 3
Bente A Talseth-Palmer; Carli M Tops; Tom van Wezel; Hans F A Vasen; Juul T Wijnen; Allan D Spigelman; Janina Suchy; Katie A Ashton; Daniel Barker; Ingvild S Brenne; Tiffany-Jane Evans; Claire Groombridge; Shantie Jagmohan-Changur; Grzegorz Kurzawski; Jan Lubinski; ML McPhillips; Pål Møller; Hans Morreau; Rodney J Scott
Combined analysis of three Lynch syndrome cohorts confirms the modifying effects of 8q23.3 and 11q23.1 in MLH1 mutation carriers.
Ronald van Eijk; Hans Morreau; Lisa Stevens; Tom van Wezel
Assessment of a fully automated high-throughput DNA extraction method from formalin-fixed, paraffin-embedded tissue for KRAS, and BRAF somatic mutation analysis.
Thomas P Potjer; Ingrid Schot; Emily P Slater; Hans F A Vasen; Martin N J M Wasser; Mathias Bargello; Detlef K Bartsch; BA Bonsing; Wouter H de Vos tot Nederveen Cappel; Thomas M Gress; Johannes T Heverhagen; Günter Klöppel; Peter Langer; Hans Morreau
Variation in precursor lesions of pancreatic cancer among high-risk groups.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Hans Morreau (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Bente A Talseth-Palmer; Carli M Tops; Tom van Wezel; Hans F A Vasen; Juul T Wijnen; Allan D Spigelman; Janina Suchy; Katie A Ashton; Daniel Barker; Ingvild S Brenne; Tiffany-Jane Evans; Claire Groombridge; Shantie Jagmohan-Changur; Grzegorz Kurzawski; Jan Lubinski; ML McPhillips; Pål Møller; Hans Morreau; Rodney J Scott
Combined analysis of three Lynch syndrome cohorts confirms the modifying effects of 8q23.3 and 11q23.1 in MLH1 mutation carriers.
International journal of cancer. Journal international du cancer 2013;132(7):1556-64.
2013: Ronald van Eijk; Hans Morreau; Lisa Stevens; Tom van Wezel
Assessment of a fully automated high-throughput DNA extraction method from formalin-fixed, paraffin-embedded tissue for KRAS, and BRAF somatic mutation analysis.
Experimental and molecular pathology 2013;94(1):121-5.
2013: Thomas P Potjer; Ingrid Schot; Emily P Slater; Hans F A Vasen; Martin N J M Wasser; Mathias Bargello; Detlef K Bartsch; BA Bonsing; Wouter H de Vos tot Nederveen Cappel; Thomas M Gress; Johannes T Heverhagen; Günter Klöppel; Peter Langer; Hans Morreau
Variation in precursor lesions of pancreatic cancer among high-risk groups.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013;19(2):442-9.
2013: Eddy H van Roon; Tom van Wezel; Arnoud Boot; Ashwin A Dihal; Robert F Ernst; Hans Morreau; Judith M Boer
BRAF mutation-specific promoter methylation of FOX genes in colorectal cancer.
Clinical epigenetics 2013;5(1):2.
2012: Stijn Crobach; Tom van Wezel; Hans F Vasen; Hans Morreau
Ovarian metastases of colorectal and duodenal cancer in familial adenomatous polyposis.
Familial cancer 2012;11(4):671-3.
2012: T C Schneider; J W A Smit; R M Abdulrahman; E P M Corssmit; Hans Morreau; Ellen Kapiteijn
Long-term analysis of the efficacy and tolerability of sorafenib in advanced radio-iodine refractory differentiated thyroid carcinoma: final results of a phase II trial.
European journal of endocrinology / European Federation of Endocrine Societies 2012;167(5):643-50.
2012: Noel F C C de Miranda; Frederik J Hes; Tom van Wezel; Hans Morreau
Role of the microenvironment in the tumourigenesis of microsatellite unstable and MUTYH-associated polyposis colorectal cancers.
Mutagenesis 2012;27(2):247-53.
2012: Tom van Wezel; Juul T Wijnen; Anneke Middeldorp; Hans Morreau
A review of the genetic background and tumour profiling in familial colorectal cancer.
Mutagenesis 2012;27(2):239-45.
2012: Noel F C C de Miranda; Danny Goudkade; Frederik J Hes; Ekaterina S. Jordanova; Carli Tops; Tom van Wezel; Hans F A Vasen; Hans Morreau
Infiltration of Lynch colorectal cancers by activated immune cells associates with early staging of the primary tumor and absence of lymph node metastases.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(5):1237-45.
2012: Niki Ottenhof; Richard van Hillegersberg; Hans Morreau; Folkert H Morsink; G Johan A Offerhaus; Margreet G E M Ausems; Wendy W J De Leng; Roeland F de Wilde; Anya N Milne
Pancreatic ductal adenocarcinoma in hereditary diffuse gastric cancer. A case report.
Human pathology 2012;43(3):457-61.
2012: PG Doornebosch; Pleun Hermsen; Imro Dawson; E J R de Graaf; Rob A E M Tollenaar; Eliane Zeestraten; Hans Morreau
Transanal endoscopic microsurgery for T1 rectal cancer: size matters!
Surgical endoscopy 2012;26(2):551-7.
2012: Willem E Corver; Noel de Miranda; Wietske C E den Hartog; Guido Hovens; Ekaterina S. Jordanova; Ellen Kapiteijn; Anneke Middeldorp; Jan Oosting; Dina Ruano; Jan Smit; Ronald van Eijk; Merlijn P van Nieuwenhuizen; Tom van Wezel; Karin Weijers; Hans Morreau
Genome haploidisation with chromosome 7 retention in oncocytic follicular thyroid carcinoma.
PloS one 2012;7(6):e38287.
2011: Arantza Fariña Sarasqueta; Ines J Goossens-Beumer; Peter J K Kuppen; V E P P Lemmens; Hans Morreau; harm rutten; Cornelis J H van de Velde; Ronald van Eijk; Gesina van Lijnschoten; Tom van Wezel; Eliane C M Zeestraten; Jan Willem T Dekker; A J C van den Brule
PIK3CA kinase domain mutation identifies a subgroup of stage III colon cancer patients with poor prognosis.
Cellular oncology (Dordrecht) 2011;34(6):523-31.
2011: Liudmila L Kodach; Hans Morreau; Maikel Peppelenbosch; Gijs R van den Brink; Tom van Wezel; Hein Verspaget; Philip W Voorneveld; Manon E Wildenberg; Daan W Hommes; Rutger J Jacobs; James C H Hardwick
Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell 'stemness' via the bone morphogenetic protein pathway.
Gut 2011;60(11):1544-53.
2011: jan pander; Sjoerd H van der burg; Tahar van der Straaten; Renée Baak-Pablo; Hans Gelderblom; Henk-Jan Guchelaar; Moniek Heusinkveld; Ekaterina S. Jordanova; Hans Morreau; Thorbald van Hall
Activation of tumor-promoting type 2 macrophages by EGFR-targeting antibody cetuximab.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(17):5668-73.
2011: Maartje Nielsen; Hans Morreau; Hans F A Vasen; Frederik J Hes
MUTYH-associated polyposis (MAP).
Critical reviews in oncology/hematology 2011;79(1):1-16.
2011: Janneke E Witteveen; Neveen Agnes Therese Hamdy; Olaf M Dekkers; Job Kievit; Tom van Wezel; Bin Tean Teh; Johannes A Romijn; Hans Morreau
Downregulation of CASR expression and global loss of parafibromin staining are strong negative determinants of prognosis in parathyroid carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2011;24(5):688-97.
2011: Marieke F Fransen; Marjolein Sluijter; Hans Morreau; Ramon Arens; Cornelis J M Melief
Local activation of CD8 T cells and systemic tumor eradication without toxicity via slow release and local delivery of agonistic CD40 antibody.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(8):2270-80.
2011: M R J Kohonen-Corish; Finlay Macrae; Maurizio Genuardi; Stefan Aretz; Bharati Bapat; Inge T Bernstein; John Burn; Richard G H Cotton; Johan T den Dunnen; Thierry Frebourg; Marc S Greenblatt; Robert Hofstra; Elke Holinski-Feder; Ilkka Lappalainen; Annika Lindblom; Donna Maglott; Pål Møller; Hans Morreau; Gabriela Möslein; Rolf Sijmons; Amanda B Spurdle; Sean V Tavtigian; Carli M J Tops; Thomas K Weber; Niels De Wind; Michael O Woods
Deciphering the colon cancer genes--report of the InSiGHT-Human Variome Project Workshop, UNESCO, Paris 2010.
Human mutation 2011;32(4):491-4.
2011: Eddy H J van Roon; Noël F C C de Miranda; Merlijn P van Nieuwenhuizen; Emile J de Meijer; Marjo Van Puijenbroek; Pearlly S Yan; Hui-Ming (Tim) Huang; Tom van Wezel; Hans Morreau; Judith M Boer
Tumour-specific methylation of PTPRG intron 1 locus in sporadic and Lynch syndrome colorectal cancer.
European journal of human genetics : EJHG 2011;19(3):307-12.
2011: Hans F A Vasen; Martin Wasser; Anneke van Mil; RA Tollenaar; Marja Konstantinovski; Nelleke A Gruis; Wilma Bergman; Frederik J Hes; Daniel W Hommes; G Johan A Offerhaus; Hans Morreau; BA Bonsing; Wouter H de Vos tot Nederveen Cappel
Magnetic resonance imaging surveillance detects early-stage pancreatic cancer in carriers of a p16-Leiden mutation.
Gastroenterology 2011;140(3):850-6.
2011: Jara M Baas; Henk-Jan Guchelaar; Lisanne L Krens; Hans Morreau; Hans Gelderblom
Concordance of predictive markers for EGFR inhibitors in primary tumors and metastases in colorectal cancer: a review.
The oncologist 2011;16(9):1239-49.
2011: Ronald van Eijk; Jappe Licht; Melanie Schrumpf; Mehrdad Talebian Yazdi; Dina Ruano; Giusi I Forte; petra nederlof; Maud Veselic; Klaus F Rabe; Jouke T Annema; Vincent Smit; Hans Morreau; Tom van Wezel
Rapid KRAS, EGFR, BRAF and PIK3CA mutation analysis of fine needle aspirates from non-small-cell lung cancer using allele-specific qPCR.
PloS one 2011;6(3):e17791.
2011: Jan van Schaik; Olaf M Dekkers; Eleonora P M van der Kleij-Corssmit; Johannes A Romijn; Hans Morreau; Cornelis J H van de Velde
Surgical treatment for unexplained severe pain of the thyroid gland: report of three cases and concise review of the literature.
Case reports in medicine 2011;2011():349756.
2011: Ramon Salazar; Paul Roepman; Gabriel Capella; Victor Moreno; Iris Simon; Christa Dreezen; Adriana Lopez-Doriga; Cristina Santos; Corrie Marijnen; Johan Westerga; Sjoerd Bruin; David Kerr; Peter Kuppen; Cornelis van de Velde; Hans Morreau; Loes Van Velthuysen; Annuska M Glas; Laura J Van't Veer; Rob Tollenaar
Gene expression signature to improve prognosis prediction of stage II and III colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(1):17-24.
2011: Janneke E Witteveen; Job Kievit; Marcel P M Stokkel; Hans Morreau; Johannes A Romijn; Neveen Agnes Therese Hamdy
Limitations of Tc99m-MIBI-SPECT imaging scans in persistent primary hyperparathyroidism.
World journal of surgery 2011;35(1):128-39.
2011: A E van der Meulen-de Jong; Hans Morreau; M C J M Becx; L F S J Crobach; M van Haastert; W R ten Hove; Jan H Kleibeuker; M A C Meijssen; Fokko M Nagengast; M C M Rijk; J M J I Salemans; A Stronkhorst; H A R E Tuynman; Juda Vecht; M L Verhulst; Wouter H de Vos tot Nederveen Cappel; H Walinga; O K Weinhardt; B D Westerveld; A M C Witte; H J Wolters; H F A Vasen
High detection rate of adenomas in familial colorectal cancer.
Gut 2011;60(1):73-6.
2010: Janneke E Witteveen; Job Kievit; Arian R van Erkel; Hans Morreau; Johannes A Romijn; Neveen Agnes Therese Hamdy
The role of selective venous sampling in the management of persistent hyperparathyroidism revisited.
European journal of endocrinology / European Federation of Endocrine Societies 2010;163(6):945-52.
2010: Maartje Nielsen; Liza N van Steenbergen; Natalie Jones; Stefanie Vogt; Hans F A Vasen; Hans Morreau; Stefan Aretz; Julian R Sampson; Olaf M Dekkers; M L G Janssen-Heijnen; Frederik J Hes
Survival of MUTYH-associated polyposis patients with colorectal cancer and matched control colorectal cancer patients.
Journal of the National Cancer Institute 2010;102(22):1724-30.
2010: Michiel F G de Maat; Norihiko Narita; Anne Benard; Tetsunori Yoshimura; Christine Kuo; Rob A E M Tollenaar; Noel F C C de Miranda; Roderick R Turner; Cornelis J H van de Velde; Hans Morreau; Dave S B Hoon
Development of sporadic microsatellite instability in colorectal tumors involves hypermethylation at methylated-in-tumor loci in adenoma.
The American journal of pathology 2010;177(5):2347-56.
2010: Alan M Pittman; Silvia Naranjo; Sanni E Jalava; Philip Twiss; Yussanne Ma; Bianca Olver; Amy Lloyd; Jayaram Vijayakrishnan; Mobshra Qureshi; Peter Broderick; Tom van Wezel; Hans Morreau; Sari Tuupanen; Lauri A Aaltonen; M Eva Alonso; Miguel Manzanares; Angela Gavilán; Tapio Visakorpi; José Luis Gómez-Skarmeta; Richard S Houlston
Allelic variation at the 8q23.3 colorectal cancer risk locus functions as a cis-acting regulator of EIF3H.
PLoS genetics 2010;6(9):.
2010: Janneke E Witteveen; Harm R Haak; Job Kievit; Hans Morreau; Johannes A Romijn; Neveen Agnes Therese Hamdy
Challenges and pitfalls in the management of parathyroid carcinoma: 17-year follow-up of a case and review of the literature.
Hormones & cancer 2010;1(4):205-14.
2010: Anneke Middeldorp; Shantie C Jagmohan-Changur; Heleen van der Klift; Marjo Van Puijenbroek; Jeanine J Houwing-Duistermaat; Emily Webb; Richard Houlston; Carli Tops; Hans F A Vasen; Peter Devilee; Hans Morreau; Tom van Wezel; Juul Wijnen
Comprehensive genetic analysis of seven large families with mismatch repair proficient colorectal cancer.
Genes, chromosomes & cancer 2010;49(6):539-48.
2010: Fania S Doekhie; Wilma E Mesker; Peter Kuppen; Gijs A van Leeuwen; Hans Morreau; Geertruida H de Bock; Hein Putter; Hans J Tanke; Cornelis J van de Velde; R A E M Tollenaar
Detailed examination of lymph nodes improves prognostication in colorectal cancer.
International journal of cancer. Journal international du cancer 2010;126(11):2644-52.
2010: Michiel F G de Maat; Cornelis J H van de Velde; Anne Benard; Hein Putter; Hans Morreau; J Han J M van Krieken; Elma Meershoek Klein-Kranenbarg; Eelco J de Graaf; Rob A E M Tollenaar; Dave S B Hoon
Identification of a quantitative MINT locus methylation profile predicting local regional recurrence of rectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(10):2811-8.
2010: Heleen van der Klift; Carli Tops; Elsa C Bik; Merel W Boogaard; Anne-Marijke Borgstein; Kerstin B M Hansson; Margreet G E M Ausems; Encarna Gomez Garcia; Andrew Green; Frederik J Hes; Louise Izatt; Liselotte P van Hest; Angel M Alonso; Annette H J T Vriends; Anja Wagner; Wendy A G van Zelst-Stams; Hans F A Vasen; Hans Morreau; Peter Devilee; Juul Wijnen
Quantification of sequence exchange events between PMS2 and PMS2CL provides a basis for improved mutation scanning of Lynch syndrome patients.
Human mutation 2010;31(5):578-87.
2010: Mark Drost; Jos e B M Zonneveld; Linda van Dijk; Hans Morreau; Carli Tops; Hans F A Vasen; Juul Wijnen; Niels De Wind
A cell-free assay for the functional analysis of variants of the mismatch repair protein MLH1.
Human mutation 2010;31(3):247-53.
2010: Janneke E Witteveen; Job Kievit; Hans Morreau; Johannes A Romijn; Neveen Agnes Therese Hamdy
No recurrence of sporadic primary hyperparathyroidism when cure is established 6 months after parathyroidectomy.
European journal of endocrinology / European Federation of Endocrine Societies 2010;162(2):399-406.
2010: Frederik J Hes; Janneke Weiss; Sanne A Woortman; Noel F de Miranda; Patrick A van Bunderen; BA Bonsing; Marcel P M Stokkel; Hans Morreau; Johannes A Romijn; Jeroen C Jansen; Annette H J T Vriends; Jean-Pierre Bayley; E P M Corssmit
Low penetrance of a SDHB mutation in a large Dutch paraganglioma family.
BMC medical genetics 2010;11():92.
2010: Eddy H J van Roon; Marjo Van Puijenbroek; Anneke Middeldorp; Ronald van Eijk; Emile J de Meijer; Dianhdra Erasmus; Kim A D Wouters; Manon van Engeland; Jan Oosting; Frederik J Hes; Carli Tops; Tom van Wezel; Judith M Boer; Hans Morreau
Early onset MSI-H colon cancer with MLH1 promoter methylation, is there a genetic predisposition?
BMC cancer 2010;10():180.
2010: Ronald van Eijk; Paul H C Eilers; Remco Natté; Anne-Marie Cleton-Jansen; Hans Morreau; Tom van Wezel; Jan Oosting
MLPAinter for MLPA interpretation: an integrated approach for the analysis, visualisation and data management of Multiplex Ligation-dependent Probe Amplification.
BMC bioinformatics 2010;11():67.
2010: Ronald van Eijk; Marjo Van Puijenbroek; Amiet R Chhatta; Nisha Gupta; Rolf H A M Vossen; Esther H Lips; Anne-Marie Cleton-Jansen; Hans Morreau; Tom van Wezel
Sensitive and specific KRAS somatic mutation analysis on whole-genome amplified DNA from archival tissues.
The Journal of molecular diagnostics : JMD 2010;12(1):27-34.
2009: Hendrieke Hoftijzer; Karen A Heemstra; Hans Morreau; Marcel P Stokkel; Eleonora P Corssmit; Hans Gelderblom; Karin Weijers; Alberto M Pereira; Maya Huijberts; Ellen Kapiteijn; Johannes A Romijn; Johannes W Smit
Beneficial effects of sorafenib on tumor progression, but not on radioiodine uptake, in patients with differentiated thyroid carcinoma.
European journal of endocrinology / European Federation of Endocrine Societies 2009;161(6):923-31.
2009: Frank M Speetjens; GJ Liefers; Cornelis J Korbee; Wilma E Mesker; Cornelis J H van de Velde; Ronald L P van Vlierberghe; Hans Morreau; R A E M Tollenaar; Peter Kuppen
Nuclear localization of CXCR4 determines prognosis for colorectal cancer patients.
Cancer microenvironment : official journal of the International Cancer Microenvironment Society 2009;2(1):1-7.
2009: Anneke Middeldorp; Shantie Jagmohan-Changur; Ronald van Eijk; Carli Tops; Peter Devilee; Hans F A Vasen; Frederik J Hes; Richard Houlston; Ian Tomlinson; Jeanine J Houwing-Duistermaat; Juul Wijnen; Hans Morreau; Tom van Wezel
Enrichment of low penetrance susceptibility loci in a Dutch familial colorectal cancer cohort.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(11):3062-7.
2009: Noel F C C de Miranda; Maartje Nielsen; Dina Pereira; Marjo Van Puijenbroek; Hans F Vasen; Frederik J Hes; Tom van Wezel; Hans Morreau
MUTYH-associated polyposis carcinomas frequently lose HLA class I expression - a common event amongst DNA-repair-deficient colorectal cancers.
The Journal of pathology 2009;219(1):69-76.
2009: Frederik J Hes; Hans Morreau
Where genetics and pathology meet: mulibrey nanism.
The Journal of pathology 2009;218(2):143-5.
2009: Maartje Nielsen; Noel F C C de Miranda; Marjo Van Puijenbroek; Ekaterina S. Jordanova; Anneke Middeldorp; Tom van Wezel; Ronald van Eijk; Carli Tops; Hans F A Vasen; Frederik J Hes; Hans Morreau
Colorectal carcinomas in MUTYH-associated polyposis display histopathological similarities to microsatellite unstable carcinomas.
BMC cancer 2009;9():184.
2009: Wilma E Mesker; Gerrit-Jan Liefers; Jan M C Junggeburt; Gabi W van Pelt; Paola Alberici; Peter J K Kuppen; Noel F Miranda; Karin A M van Leeuwen; Hans Morreau; Karoly Szuhai; R A E M Tollenaar; Hans J Tanke
Presence of a high amount of stroma and downregulation of SMAD4 predict for worse survival for stage I-II colon cancer patients.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2009;31(3):169-78.
2009: Juul Wijnen; Richard M Brohet; Ronald van Eijk; Shantie Jagmohan-Changur; Anneke Middeldorp; Carli Tops; Mario van Puijenbroek; Margreet G E M Ausems; Encarna Gómez García; Frederik J Hes; Nicoline Hoogerbrugge; Fred H Menko; Theo A M van Os; Rolf Sijmons; Senno Verhoef; Anja Wagner; Fokko M Nagengast; Jan H Kleibeuker; Peter Devilee; Hans Morreau; David Goldgar; Ian P M Tomlinson; richard Houlston; Tom van Wezel; H F A Vasen
Chromosome 8q23.3 and 11q23.1 variants modify colorectal cancer risk in Lynch syndrome.
Gastroenterology 2009;136(1):131-7.
2008: Fania S Doekhie; Hans Morreau; Geertruida H de Bock; Frank M Speetjens; N Geeske Dekker-Ensink; Hein Putter; Cornelis J H van de Velde; Rob A E M Tollenaar; Peter J K Kuppen
Sialyl Lewis X expression and lymphatic microvessel density in primary tumors of node-negative colorectal cancer patients predict disease recurrence.
Cancer microenvironment : official journal of the International Cancer Microenvironment Society 2008;1(1):141-51.
2008: Rinke Bos; Suzanne van Duikeren; Hans Morreau; Kees L M C Franken; Schumacher Ton; John B Haanen; Sjoerd H van der burg; Cornelis J M Melief; Rienk Offringa
Balancing between antitumor efficacy and autoimmune pathology in T-cell-mediated targeting of carcinoembryonic antigen.
Cancer research 2008;68(20):8446-55.
2008: Jan Willem F Dierssen; Marjo Van Puijenbroek; David A Dezentjé; Gert Jan Fleuren; Cees J Cornelisse; Tom van Wezel; Rienk Offringa; Hans Morreau
Frequent mutations in the 3'-untranslated region of IFNGR1 lack functional impairment in microsatellite-unstable colorectal tumours.
European journal of human genetics : EJHG 2008;16(10):1235-9.
2008: A Middeldorp; Marjo Van Puijenbroek; M Nielsen; W E Corver; Ekaterina S. Jordanova; Natalja T Ter Haar; C M J Tops; H F A Vasen; E H Lips; Ronald van Eijk; F J Hes; Jan Oosting; Juul Wijnen; Tom van Wezel; Hans Morreau
High frequency of copy-neutral LOH in MUTYH-associated polyposis carcinomas.
The Journal of pathology 2008;216(1):25-31.
2008: Frank M Speetjens; Marjolein M Lauwen; Kees L M C Franken; Connie M Janssen-Van Rhijn; Suzanne van Duikeren; Sandra A Bres; Cornelis J H van de Velde; Cornelis J M Melief; Peter Kuppen; Sjoerd H van der burg; Hans Morreau; Rienk Offringa
Prediction of the immunogenic potential of frameshift-mutated antigens in microsatellite instable cancer.
International journal of cancer. Journal international du cancer 2008;123(4):838-45.
2008: Frank M Speetjens; Peter Kuppen; Hans Morreau; Sjoerd H van der burg
Immune response against frameshift-induced neopeptides in HNPCC patients and healthy HNPCC mutation carriers.
Gastroenterology 2008;135(2):711-2; author reply 712-3.
2008: Liudmila L Kodach; Eliza Wiercinska; Noel F C C de Miranda; Sylvia A Bleuming; Alex R Musler; Maikel Peppelenbosch; Evelien Dekker; Gijs R van den Brink; Carel J M van Noesel; Hans Morreau; Daan W Hommes; Peter ten Dijke; G Johan A Offerhaus; James C H Hardwick
The bone morphogenetic protein pathway is inactivated in the majority of sporadic colorectal cancers.
Gastroenterology 2008;134(5):1332-41.
2008: Erica G D Hopman; Mary E von Blomberg; Manou R Batstra; Hans Morreau; Friedo W Dekker; Frits Koning; Cor B H W Lamers; M Luisa Mearin
Gluten tolerance in adult patients with celiac disease 20 years after diagnosis?
European journal of gastroenterology & hepatology 2008;20(5):423-9.
2008: Claudia Gaspar; Joana Cardoso; Patrick Franken; Lia Molenaar; Hans Morreau; Gabriela Möslein; Julian Sampson; Judith M Boer; Renée X de Menezes; Riccardo Fodde
Cross-species comparison of human and mouse intestinal polyps reveals conserved mechanisms in adenomatous polyposis coli (APC)-driven tumorigenesis.
The American journal of pathology 2008;172(5):1363-80.
2008: Frank M Speetjens; Elza C de Bruin; Hans Morreau; Eliane C M Zeestraten; Hein Putter; J Han van Krieken; Maaike M van Buren; Monique van Velzen; N Geeske Dekker-Ensink; Cornelis J H van de Velde; Peter Kuppen
Clinical impact of HLA class I expression in rectal cancer.
Cancer immunology, immunotherapy : CII 2008;57(5):601-9.
2008: Ying Y Liu; Marcel P M Stokkel; Hans Morreau; Alberto M Pereira; Johannes A Romijn; Jan W A Smit
Radioiodine therapy after pretreatment with bexarotene for metastases of differentiated thyroid carcinoma.
Clinical endocrinology 2008;68(4):605-9.
2008: Ying Y Liu; Hans Morreau; Job Kievit; Johannes A Romijn; Nancy Carrasco; Jan W A Smit
Combined immunostaining with galectin-3, fibronectin-1, CITED-1, Hector Battifora mesothelial-1, cytokeratin-19, peroxisome proliferator-activated receptor-{gamma}, and sodium/iodide symporter antibodies for the differential diagnosis of non-medullary thyroid carcinoma.
European journal of endocrinology / European Federation of Endocrine Societies 2008;158(3):375-84.
2008: Esther H Lips; Ronald van Eijk; E J R de Graaf; PG Doornebosch; Noel F C C de Miranda; Jan Oosting; Tom Karsten; Paul H C Eilers; R A E M Tollenaar; Tom van Wezel; Hans Morreau
Progression and tumor heterogeneity analysis in early rectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(3):772-81.
2008: Esther H Lips; Ronald van Eijk; E J R de Graaf; Jan Oosting; Noel F C C de Miranda; Tom Karsten; Cornelis J van de Velde; Paul H C Eilers; R A E M Tollenaar; Tom van Wezel; Hans Morreau
Integrating chromosomal aberrations and gene expression profiles to dissect rectal tumorigenesis.
BMC cancer 2008;8():314.
2008: Marjo Van Puijenbroek; Anneke Middeldorp; Carli Tops; Ronald van Eijk; Heleen van der Klift; H F A Vasen; Juul Wijnen; Frederik J Hes; Jan Oosting; Tom van Wezel; Hans Morreau
Genome-wide copy neutral LOH is infrequent in familial and sporadic microsatellite unstable carcinomas.
Familial cancer 2008;7(4):319-30.
2008: Marjo Van Puijenbroek; Maartje Nielsen; Carli Tops; Hans Halfwerk; H F A Vasen; Janneke Weiss; Tom van Wezel; Frederik J Hes; Hans Morreau
Identification of patients with (atypical) MUTYH-associated polyposis by KRAS2 c.34G > T prescreening followed by MUTYH hotspot analysis in formalin-fixed paraffin-embedded tissue.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(1):139-42.
2007: Ana Sánchez de Abajo; Miguel de la Hoya; Marjo Van Puijenbroek; Alicia Tosar; J A López-Asenjo; Eduardo Díaz-Rubio; Hans Morreau; Trinidad Caldes
Molecular analysis of colorectal cancer tumors from patients with mismatch repair proficient hereditary nonpolyposis colorectal cancer suggests novel carcinogenic pathways.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(19):5729-35.
2007: Carola J Haven; Marjo Van Puijenbroek; M H Tan; Bin Tean Teh; Gert Jan Fleuren; Tom van Wezel; Hans Morreau
Identification of MEN1 and HRPT2 somatic mutations in paraffin-embedded (sporadic) parathyroid carcinomas.
Clinical endocrinology 2007;67(3):370-6.
2007: Esther H Lips; E J R de Graaf; R A E M Tollenaar; Ronald van Eijk; Jan Oosting; Karoly Szuhai; T Karsten; Y Nanya; S Ogawa; Cornelis J H van de Velde; Paul H C Eilers; Tom van Wezel; Hans Morreau
Single nucleotide polymorphism array analysis of chromosomal instability patterns discriminates rectal adenomas from carcinomas.
The Journal of pathology 2007;212(3):269-77.
2007: Maartje Nielsen; Frederik J Hes; Fokko M Nagengast; Janneke Weiss; E M H Mathus-Vliegen; Hans Morreau; Martijn H Breuning; Juul Wijnen; Carli Tops; H F A Vasen
Germline mutations in APC and MUTYH are responsible for the majority of families with attenuated familial adenomatous polyposis.
Clinical genetics 2007;71(5):427-33.
2007: Jan Oosting; Esther H Lips; Ronald van Eijk; Paul H C Eilers; Karoly Szuhai; Cisca Wijmenga; Hans Morreau; Tom van Wezel
High-resolution copy number analysis of paraffin-embedded archival tissue using SNP BeadArrays.
Genome research 2007;17(3):368-76.
2007: Wilma E Mesker; Jan M C Junggeburt; Karoly Szuhai; Pieter De Heer; Hans Morreau; Hans J Tanke; R A E M Tollenaar
The carcinoma-stromal ratio of colon carcinoma is an independent factor for survival compared to lymph node status and tumor stage.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2007;29(5):387-98.
2007: Jan Willem F Dierssen; Noel F C C de Miranda; Soldano Ferrone; Marjo Van Puijenbroek; Cees J Cornelisse; Gert Jan Fleuren; Tom van Wezel; Hans Morreau
HNPCC versus sporadic microsatellite-unstable colon cancers follow different routes toward loss of HLA class I expression.
BMC cancer 2007;7():33.
2007: Anneke Middeldorp; Shantie Jagmohan-Changur; Quinta Helmer; Heleen van der Klift; Carli Tops; H F A Vasen; Peter Devilee; Hans Morreau; Jeanine J Houwing-Duistermaat; Juul Wijnen; Tom van Wezel
A procedure for the detection of linkage with high density SNP arrays in a large pedigree with colorectal cancer.
BMC cancer 2007;7():6.
2007: Marjo Van Puijenbroek; Maartje Nielsen; Tjitske H C M Reinards; Janneke Weiss; Anja Wagner; Yvonne M C Hendriks; H F A Vasen; Carli Tops; Juul Wijnen; Tom van Wezel; Frederik J Hes; Hans Morreau
The natural history of a combined defect in MSH6 and MUTYH in a HNPCC family.
Familial cancer 2007;6(1):43-51.
2007: Joana Cardoso; Judith M Boer; Hans Morreau; Riccardo Fodde
Expression and genomic profiling of colorectal cancer.
Biochimica et biophysica acta 2007;1775(1):103-37.
2006: Maartje Nielsen; J W Poley; Senno Verhoef; Marjo Van Puijenbroek; Janneke Weiss; G T Burger; Charlotte Dommering; H F A Vasen; Ernst J Kuipers; Anja Wagner; Hans Morreau; Frederik J Hes
Duodenal carcinoma in MUTYH-associated polyposis.
Journal of clinical pathology 2006;59(11):1212-5.
2006: Yvonne M C Hendriks; Andrea E De Jong; Hans Morreau; Carli Tops; H F A Vasen; Juul Wijnen; Martijn H Breuning; Annette H J T Bröcker-Vriends
Diagnostic approach and management of Lynch syndrome (hereditary nonpolyposis colorectal carcinoma): a guide for clinicians.
CA: a cancer journal for clinicians 2006;56(4):213-25.
2006: Fania S Doekhie; Peter Kuppen; K C M J Peeters; Wilma E Mesker; Ronald A van Soest; Hans Morreau; Cornelis J H van de Velde; Hans J Tanke; R A E M Tollenaar
Prognostic relevance of occult tumour cells in lymph nodes in colorectal cancer.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2006;32(3):253-8.
2006: Ana Sanchez de Abajo; Miguel de la Hoya; Marjo Van Puijenbroek; Javier Godino; Eduardo Díaz-Rubio; Hans Morreau; Trinidad Caldes
Dual role of LOH at MMR loci in hereditary non-polyposis colorectal cancer?
Oncogene 2006;25(14):2124-30.
2006: Rogier A Oldenburg; Karin Kroeze-Jansema; Hanne Meijers-Heijboer; Christi J van Asperen; Nicoline Hoogerbrugge; Inge van Leeuwen; H F A Vasen; Anne-Marie Cleton-Jansen; Jaennelle Kraan; Jeanine J Houwing-Duistermaat; Hans Morreau; Cees J Cornelisse; Peter Devilee
Characterization of familial non-BRCA1/2 breast tumors by loss of heterozygosity and immunophenotyping.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(6):1693-700.
2006: Joana Cardoso; Lia Molenaar; Renée X de Menezes; Monique van Leerdam; Carla Rosenberg; Gabriela Möslein; Julian Sampson; Hans Morreau; Judith M Boer; Riccardo Fodde
Chromosomal instability in MYH- and APC-mutant adenomatous polyps.
Cancer research 2006;66(5):2514-9.
2006: Yvonne M C Hendriks; Shantie Jagmohan-Changur; Heleen van der Klift; Hans Morreau; Marjo Van Puijenbroek; Carli Tops; Theo A M van Os; Anja Wagner; Margreet G E M Ausems; Encarna Gomez; Martijn H Breuning; Annette H J T Bröcker-Vriends; H F A Vasen; Juul Wijnen
Heterozygous mutations in PMS2 cause hereditary nonpolyposis colorectal carcinoma (Lynch syndrome).
Gastroenterology 2006;130(2):312-22.
2006: Jan Willem F Dierssen; Noel F C C de Miranda; Arend Mulder; Marjo Van Puijenbroek; Willem Verduyn; Frans H J Claas; Cornelis J H van de Velde; Gert Jan Fleuren; Cees J Cornelisse; Willem E Corver; Hans Morreau
High-resolution analysis of HLA class I alterations in colorectal cancer.
BMC cancer 2006;6():233.
2005: Esther H Lips; Jan Willem F Dierssen; Ronald van Eijk; Jan Oosting; Paul H C Eilers; R A E M Tollenaar; E J R de Graaf; Ruben van't Slot; Cisca Wijmenga; Hans Morreau; Tom van Wezel
Reliable high-throughput genotyping and loss-of-heterozygosity detection in formalin-fixed, paraffin-embedded tumors using single nucleotide polymorphism arrays.
Cancer research 2005;65(22):10188-91.
2005: Marjo Van Puijenbroek; Jan Willem F Dierssen; Patrick Stanssens; Ronald van Eijk; Anne-Marie Cleton-Jansen; Tom van Wezel; Hans Morreau
Mass spectrometry-based loss of heterozygosity analysis of single-nucleotide polymorphism loci in paraffin embedded tumors using the MassEXTEND assay: single-nucleotide polymorphism loss of heterozygosity analysis of the protein tyrosine phosphatase receptor type J in familial colorectal cancer.
The Journal of molecular diagnostics : JMD 2005;7(5):623-30.
2005: Fania S Doekhie; K C M J Peeters; Peter Kuppen; Wilma E Mesker; Hans J Tanke; Hans Morreau; Cornelis J H van de Velde; R A E M Tollenaar
The feasibility and reliability of sentinel node mapping in colorectal cancer.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2005;31(8):854-62.
2005: Maartje Nielsen; Patrick F Franken; T H C M Reinards; Janneke Weiss; Anja Wagner; Heleen van der Klift; S Kloosterman; J J Houwing-Duistermaat; Cora M Aalfs; Margreet G E M Ausems; Annette H J T Bröcker-Vriends; E B Gomez Garcia; Nicoline Hoogerbrugge; Fred H Menko; Rolf Sijmons; Senno Verhoef; Ernst J Kuipers; Hans Morreau; Martijn H Breuning; Carli Tops; Juul Wijnen; H F A Vasen; Riccardo Fodde; Frederik J Hes
Multiplicity in polyp count and extracolonic manifestations in 40 Dutch patients with MYH associated polyposis coli (MAP).
Journal of medical genetics 2005;42(9):e54.
2005: Marco Agostini; Maria Grazia Tibiletti; Emanuela Lucci-Cordisco; Annamaria Chiaravalli; Hans Morreau; Daniela Furlan; Luigi Boccuto; Salvatore Pucciarelli; Carlo Capella; Mauro Boiocchi; Alessandra Viel
Two PMS2 mutations in a Turcot syndrome family with small bowel cancers.
The American journal of gastroenterology 2005;100(8):1886-91.
2005: P F Wang; M-H Tan; Chun Zhang; Hans Morreau; Bin Tean Teh
HRPT2, a tumor suppressor gene for hyperparathyroidism-jaw tumor syndrome.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2005;37(6):380-3.
2005: Marjo Van Puijenbroek; Christi J van Asperen; Anneke van Mil; Peter Devilee; Tom van Wezel; Hans Morreau
Homozygosity for a CHEK2*1100delC mutation identified in familial colorectal cancer does not lead to a severe clinical phenotype.
The Journal of pathology 2005;206(2):198-204.
2005: Maro H Sandel; Alisher R Dadabayev; Anand G Menon; Hans Morreau; Cornelis J M Melief; Rienk Offringa; Sjoerd H van der burg; Connie M Janssen-Van Rhijn; N Geeske Ensink; R A E M Tollenaar; Cornelis J H van de Velde; Peter Kuppen
Prognostic value of tumor-infiltrating dendritic cells in colorectal cancer: role of maturation status and intratumoral localization.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(7):2576-82.
2005: Andrea E De Jong; Hans Morreau; Fokko M Nagengast; E M H Mathus-Vliegen; Jan H Kleibeuker; Gerrit Griffioen; Annemieke Cats; H F A Vasen
Prevalence of adenomas among young individuals at average risk for colorectal cancer.
The American journal of gastroenterology 2005;100(1):139-43.
2004: Alisher R Dadabayev; Maro H Sandel; Anand G Menon; Hans Morreau; Cornelis J M Melief; Rienk Offringa; Sjoerd H van der burg; Connie M Janssen-Van Rhijn; N Geeske Ensink; R A E M Tollenaar; Cornelis J H van de Velde; Peter Kuppen
Dendritic cells in colorectal cancer correlate with other tumor-infiltrating immune cells.
Cancer immunology, immunotherapy : CII 2004;53(11):978-86.
2004: Carola J Haven; Viive M Howell; Paul H C Eilers; Robert Dunne; Masayuki Takahashi; Marjo Van Puijenbroek; Kyle A Furge; Job Kievit; Min-Han Tan; Gert Jan Fleuren; Bruce G Robinson; Leigh W Delbridge; Jeanette Philips; Anne E Nelson; Ulf Krause; Henning Dralle; Cuong Hoang-Vu; Oliver Gimm; Hans Morreau; Deborah J Marsh; Bin Tean Teh
Gene expression of parathyroid tumors: molecular subclassification and identification of the potential malignant phenotype.
Cancer research 2004;64(20):7405-11.
2004: Min-Han Tan; Carl Morrison; Pengfei Wang; Ximing Yang; Carola J Haven; Chun Zhang; Ping Zhao; Maria Tretiakova; Eeva Korpi-Hyovalti; John R Burgess; Khee Chee Soo; Wei-Keat Cheah; Brian Cao; James Resau; Hans Morreau; Bin Tean Teh
Loss of parafibromin immunoreactivity is a distinguishing feature of parathyroid carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(19):6629-37.
2004: Yvonne M C Hendriks; Anja Wagner; Hans Morreau; Fred H Menko; Astrid T Stormorken; Franz Quehenberger; Lodewijk A Sandkuijl; Pål Møller; Maurizio Genuardi; Hans C van Houwelingen; Carli Tops; Marjo Van Puijenbroek; Paul Verkuijlen; Gemma G Kenter; Anneke Van Mil; Hanne Meijers-Heijboer; Gita B Tan; Martijn H Breuning; Riccardo Fodde; Juul Wijnen; Annette H J T Bröcker-Vriends; H F A Vasen
Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance.
Gastroenterology 2004;127(1):17-25.
2004: Wouter H de Vos tot Nederveen Cappel; Hielke J Meulenbeld; Jan H Kleibeuker; Fokko M Nagengast; Fred H Menko; Gerrit Griffioen; Annemieke Cats; Hans Morreau; Hans Gelderblom; H F A Vasen
Survival after adjuvant 5-FU treatment for stage III colon cancer in hereditary nonpolyposis colorectal cancer.
International journal of cancer. Journal international du cancer 2004;109(3):468-71.
2004: Anand G Menon; Connie M Janssen-Van Rhijn; Hans Morreau; Hein Putter; R A E M Tollenaar; Cornelis J H van de Velde; Gert Jan Fleuren; Peter Kuppen
Immune system and prognosis in colorectal cancer: a detailed immunohistochemical analysis.
Laboratory investigation; a journal of technical methods and pathology 2004;84(4):493-501.
2004: Rogier A Oldenburg; Wouter H de Vos tot Nederveen Cappel; Marjo Van Puijenbroek; Ans M W van den Ouweland; Egbert Bakker; Gerrit Griffioen; Peter Devilee; Cees J Cornelisse; Hanne Meijers-Heijboer; H F A Vasen; Hans Morreau
Extending the p16-Leiden tumour spectrum by respiratory tract tumours.
Journal of medical genetics 2004;41(3):e31.
2004: Erwin Pauws; Geertruda J M Veenboer; Jan W A Smit; Jan J M de Vijlder; Hans Morreau; Carrie Ris Stalpers
Genes differentially expressed in thyroid carcinoma identified by comparison of SAGE expression profiles.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(3):560-1.
2004: Andrea E De Jong; Marjo Van Puijenbroek; Yvonne M C Hendriks; Carli Tops; Juul Wijnen; Margreet G E M Ausems; Hanne Meijers-Heijboer; Anja Wagner; Theo A M van Os; Annette H J T Bröcker-Vriends; H F A Vasen; Hans Morreau
Microsatellite instability, immunohistochemistry, and additional PMS2 staining in suspected hereditary nonpolyposis colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(3):972-80.
2004: Deborah J Marsh; Hans Morreau; Bin Tean Teh
HRPT2 and parathyroid cancer.
The lancet oncology 2004;5(2):78.
2004: H F A Vasen; Yvonne M C Hendriks; Andrea E De Jong; Marjo Van Puijenbroek; Carli Tops; Annette H J T Bröcker-Vriends; Juul Wijnen; Hans Morreau
Identification of HNPCC by molecular analysis of colorectal and endometrial tumors.
Disease markers 2004;20(4-5):207-13.
2004: Joana Cardoso; Lia Molenaar; Renée X de Menezes; Carla Rosenberg; Hans Morreau; Gabriela Möslein; Riccardo Fodde; Judith M Boer
Genomic profiling by DNA amplification of laser capture microdissected tissues and array CGH.
Nucleic acids research 2004;32(19):e146.
2004: Bin Tean Teh; Viive M Howell; Carola J Haven; Katherine Kahnoski; Sok Kean Khoo; David Petillo; Jindong Chen; Gert Jan Fleuren; Bruce G Robinson; Leigh W Delbridge; Jeanette Philips; Anne E Nelson; Ulf Krause; K Hammje; Henning Dralle; Cuong Hoang-Vu; Oliver Gimm; Deborah J Marsh; Hans Morreau
Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.
Human genetics 2004;114(2):224.
2004: Bin Tean Teh; Viive M Howell; Carola J Haven; Katherine Kahnoski; Sok Kean Khoo; David Petillo; Jindong Chen; Gert Jan Fleuren; Bruce G Robinson; Leigh W Delbridge; Jeanette Philips; Anne E Nelson; Ulf Krause; K Hammje; Henning Dralle; Cuong Hoang-Vu; Oliver Gimm; Deborah J Marsh; Hans Morreau
Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.
Human genetics 2004;114(2):223.
2004: Bin Tean Teh; Viive M Howell; Carola J Haven; Katherine Kahnoski; Sok Kean Khoo; David Petillo; Jindong Chen; Gert Jan Fleuren; Bruce G Robinson; Leigh W Delbridge; Jeanette Philips; Anne E Nelson; Ulf Krause; K Hammje; Henning Dralle; Cuong Hoang-Vu; Oliver Gimm; Deborah J Marsh; Hans Morreau
Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.
Human genetics 2004;114(2):223.
2004: Bin Tean Teh; Viive M Howell; Carola J Haven; Katherine Kahnoski; Sok Kean Khoo; David Petillo; Jindong Chen; Gert Jan Fleuren; Bruce G Robinson; Leigh W Delbridge; Jeanette Philips; Anne E Nelson; Ulf Krause; K Hammje; Henning Dralle; Cuong Hoang-Vu; Oliver Gimm; Deborah J Marsh; Hans Morreau
Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.
Human genetics 2004;114(2):223.
2004: Bin Tean Teh; Viive M Howell; Carola J Haven; Katherine Kahnoski; Sok Kean Khoo; David Petillo; Jindong Chen; Gert Jan Fleuren; Bruce G Robinson; Leigh W Delbridge; Jeanette Philips; Anne E Nelson; Ulf Krause; K Hammje; Henning Dralle; Cuong Hoang-Vu; Oliver Gimm; Deborah J Marsh; Hans Morreau
Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.
Human genetics 2004;114(2):222.
2004: Bin Tean Teh; Viive M Howell; Carola J Haven; Katherine Kahnoski; Sok Kean Khoo; David Petillo; Jindong Chen; Gert Jan Fleuren; Bruce G Robinson; Leigh W Delbridge; Jeanette Philips; Anne E Nelson; Ulf Krause; K Hammje; Henning Dralle; Cuong Hoang-Vu; Oliver Gimm; Deborah J Marsh; Hans Morreau
Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.
Human genetics 2004;114(2):222.
2004: Bin Tean Teh; Viive M Howell; Carola J Haven; Katherine Kahnoski; Sok Kean Khoo; David Petillo; Jindong Chen; Gert Jan Fleuren; Bruce G Robinson; Leigh W Delbridge; Jeanette Philips; Anne E Nelson; Ulf Krause; K Hammje; Henning Dralle; Cuong Hoang-Vu; Oliver Gimm; Deborah J Marsh; Hans Morreau
Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.
Human genetics 2004;114(2):221.
2004: Alberto M Pereira; Sjoerd W van Thiel; Jonathan R Lindner; Ferdinand Roelfsema; Ernst E van der Wall; Hans Morreau; Jan W A Smit; Johannes A Romijn; Jeroen J Bax
Increased prevalence of regurgitant valvular heart disease in acromegaly.
The Journal of clinical endocrinology and metabolism 2004;89(1):71-5.
2004: Andrea E De Jong; Hans Morreau; Marjo Van Puijenbroek; Paul H C Eilers; Juul Wijnen; Fokko M Nagengast; Gerrit Griffioen; Annemieke Cats; Fred H Menko; Jan H Kleibeuker; H F A Vasen
The role of mismatch repair gene defects in the development of adenomas in patients with HNPCC.
Gastroenterology 2004;126(1):42-8.
2004: Carola J Haven; Marjo Van Puijenbroek; Marcel Karperien; Gert Jan Fleuren; Hans Morreau
Differential expression of the calcium sensing receptor and combined loss of chromosomes 1q and 11q in parathyroid carcinoma.
The Journal of pathology 2004;202(1):86-94.
2003: Rogier A Oldenburg; Karin Kroeze-Jansema; Jaennelle Kraan; Hans Morreau; Jan G M Klijn; Nicoline Hoogerbrugge; M J L Ligtenberg; Christi J van Asperen; H F A Vasen; Carel Meijers; Hanne Meijers-Heijboer; Truuske H de Bock; Cees J Cornelisse; Peter Devilee
The CHEK2*1100delC variant acts as a breast cancer risk modifier in non-BRCA1/BRCA2 multiple-case families.
Cancer research 2003;63(23):8153-7.
2003: Wilma E Mesker; Fania S Doekhie; Hans Vrolijk; Rob Keyzer; Willem C R Sloos; Hans Morreau; Paddy S O'Kelly; Geertruida H de Bock; R A E M Tollenaar; Hans J Tanke
Automated analysis of multiple sections for the detection of occult cells in lymph nodes.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(13):4826-34.
2003: Wouter H de Vos tot Nederveen Cappel; G Johan A Offerhaus; Marjo Van Puijenbroek; Eric Caspers; Nelleke A Gruis; Femke A De Snoo; Cornelis B H W Lamers; Gerrit Griffioen; Wilma Bergman; H F A Vasen; Hans Morreau
Pancreatic carcinoma in carriers of a specific 19 base pair deletion of CDKN2A/p16 (p16-leiden).
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(10 Pt 1):3598-605.
2003: Viive M Howell; Carola J Haven; Katherine Kahnoski; Sok Kean Khoo; David Petillo; Jindong Chen; Gert Jan Fleuren; Bruce G Robinson; Leigh W Delbridge; Jeanette Philips; Anne E Nelson; Ulf Krause; K Hammje; Henning Dralle; Cuong Hoang-Vu; Oliver Gimm; Deborah J Marsh; Hans Morreau; Bin Tean Teh
HRPT2 mutations are associated with malignancy in sporadic parathyroid tumours.
Journal of medical genetics 2003;40(9):657-63.
2003: Hans Vrolijk; Willem C R Sloos; Wilma E Mesker; Patrick Franken; Riccardo Fodde; Hans Morreau; Hans J Tanke
Automated acquisition of stained tissue microarrays for high-throughput evaluation of molecular targets.
The Journal of molecular diagnostics : JMD 2003;5(3):160-7.
2003: Anand G Menon; Peter Kuppen; Sjoerd H van der burg; Rienk Offringa; Marie-Claude Bonnet; Bert I J Harinck; R A E M Tollenaar; Anke Redeker; Hein Putter; Philippe Moingeon; Hans Morreau; Cornelis J M Melief; Cornelis J H van de Velde
Safety of intravenous administration of a canarypox virus encoding the human wild-type p53 gene in colorectal cancer patients.
Cancer gene therapy 2003;10(7):509-17.
2003: Anja Wagner; Alicia Barrows; Juul Wijnen; Heleen van der Klift; Patrick F Franken; Paul Verkuijlen; Hidewaki Nakagawa; Marjan Geugien; Shantie Jaghmohan-Changur; Cor Breukel; Hanne Meijers-Heijboer; Hans Morreau; Marjo Van Puijenbroek; John Burn; Stephanie M Coronel; Yulia Kinarski; Ross Okimoto; Patrice Watson; Jane F Lynch; Albert de La Chapelle; Henry T Lynch; Riccardo Fodde
Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene.
American journal of human genetics 2003;72(5):1088-100.
2003: Wiljo J F De Leeuw; Marjo Van Puijenbroek; R A E M Tollenaar; Cees J Cornelisse; H F A Vasen; Hans Morreau
Correspondence re: A. Müller et al., Exclusion of breast cancer as an integral tumor of hereditary nonpolyposis colorectal cancer. Cancer Res., 62: 1014-1019, 2002.
Cancer research 2003;63(5):1148-9.
2003: Peter Hohenstein; Lia Molenaar; Joyce Dijs-Elsinga; Hans Morreau; Heleen van der Klift; Ada Struijk; Shantie Jagmohan-Changur; Ron Smits; Henk J van Kranen; Gert-Jan B van Ommen; Cees J Cornelisse; Peter Devilee; Riccardo Fodde
Serrated adenomas and mixed polyposis caused by a splice acceptor deletion in the mouse Smad4 gene.
Genes, chromosomes & cancer 2003;36(3):273-82.
2003: Yvonne M C Hendriks; Patrick Franken; Jan Willem F Dierssen; Wiljo J F De Leeuw; Juul Wijnen; Enno J Dreef; Carli Tops; Martijn H Breuning; Annette H J T Bröcker-Vriends; H F A Vasen; Riccardo Fodde; Hans Morreau
Conventional and tissue microarray immunohistochemical expression analysis of mismatch repair in hereditary colorectal tumors.
The American journal of pathology 2003;162(2):469-77.
2003: Wouter H de Vos tot Nederveen Cappel; M A C Lagendijk; Cornelis B H W Lamers; Hans Morreau; H F A Vasen
Surveillance for familial pancreatic cancer.
Scandinavian journal of gastroenterology. Supplement 2003;(239):94-9.
2002: Anand G Menon; Hans Morreau; R A E M Tollenaar; E Alphenaar; Marjo Van Puijenbroek; Hein Putter; Connie M Janssen-Van Rhijn; Cornelis J H van de Velde; Gert Jan Fleuren; Peter Kuppen
Down-regulation of HLA-A expression correlates with a better prognosis in colorectal cancer patients.
Laboratory investigation; a journal of technical methods and pathology 2002;82(12):1725-33.
2002: Dominique E S Boks; Aliana P Trujillo; Adri C Voogd; Hans Morreau; Gemma G Kenter; H F A Vasen
Survival analysis of endometrial carcinoma associated with hereditary nonpolyposis colorectal cancer.
International journal of cancer. Journal international du cancer 2002;102(2):198-200.
2001: Jan W A Smit; Shama L van Zelderen-Bhola; R Merx; Wiljo J F De Leeuw; Hans W Wessels; R Vink; Hans Morreau
A novel chromosomal translocation t(3;5)(q12;p15.3) and loss of heterozygosity on chromosome 22 in a multifocal follicular variant of papillary thyroid carcinoma presenting with skin metastases.
Clinical endocrinology 2001;55(4):543-8.
2001: Wiljo J F De Leeuw; Marjo Van Puijenbroek; R Merx; Juul Wijnen; Annette H J T Bröcker-Vriends; Carli Tops; H F A Vasen; Cees J Cornelisse; Hans Morreau
Bias in detection of instability of the (C)8 mononucleotide repeat of MSH6 in tumours from HNPCC patients.
Oncogene 2001;20(43):6241-4.
2001: Liesbeth E Jonges; J Fred Nagelkerke; N Geeske Ensink; Edo A van der Velde; R A E M Tollenaar; Gert Jan Fleuren; Cornelis J H van de Velde; Hans Morreau; Peter Kuppen
Caspase-3 activity as a prognostic factor in colorectal carcinoma.
Laboratory investigation; a journal of technical methods and pathology 2001;81(5):681-8.
2001: Anja Wagner; Yvonne M C Hendriks; E Johanna Meijers-Heijboer; Wiljo J F De Leeuw; Hans Morreau; Robert M W Hofstra; Carli Tops; E Bik; Annette H J T Bröcker-Vriends; Conny A van der Meer; Dick Lindhout; H F A Vasen; Martijn H Breuning; Cees J Cornelisse; C van Krimpen; Martinus F Niermeijer; A H Zwinderman; Juul Wijnen; Riccardo Fodde
Atypical HNPCC owing to MSH6 germline mutations: analysis of a large Dutch pedigree.
Journal of medical genetics 2001;38(5):318-22.
2001: W Müller; Lawrence J Burgart; R Krause-Paulus; Stephen N Thibodeau; M Almeida; Tina Bocker Edmonston; C R Boland; Christian Sutter; Jeremy R Jass; A Lindblom; J Lubinski; K MacDermot; D S Sanders; Hans Morreau; Annegret Müller; Cristina Oliani; T Orntoft; Maurizio Ponz de Leon; C Rosty; M Rodriguez-Bigas; Josef Rüschoff; Andrew Ruszkiewicz; J Sabourin; R Salovaara; Gabriela Möslein
The reliability of immunohistochemistry as a prescreening method for the diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC)--results of an international collaborative study.
Familial cancer 2001;1(2):87-92.
2000: T Peelen; Wiljo J F De Leeuw; K van Lent; Hans Morreau; Ronald van Eijk; Marcel van Vliet; Juul Wijnen; M J L Ligtenberg; HB Ginjaar; R Zweemer; Fred H Menko; Riccardo Fodde; Gert-Jan B van Ommen; H F A Vasen; Cees J Cornelisse; Peter Devilee
Genetic analysis of a breast-ovarian cancer family, with 7 cases of colorectal cancer linked to BRCA1, fails to support a role for BRCA1 in colorectal tumorigenesis.
International journal of cancer. Journal international du cancer 2000;88(5):778-82.
2000: Wiljo J F De Leeuw; Jan Willem F Dierssen; H F A Vasen; Juul Wijnen; Gemma G Kenter; Hanne Meijers-Heijboer; A Brocker-Vriends; Astrid T Stormorken; Pal Moller; Fred H Menko; Cees J Cornelisse; Hans Morreau
Prediction of a mismatch repair gene defect by microsatellite instability and immunohistochemical analysis in endometrial tumours from HNPCC patients.
The Journal of pathology 2000;192(3):328-35.
2000: Carola J Haven; F K Wong; Eveline W C M Van Dam; R van der Juijt; Christi J van Asperen; J Jansen; C Rosenberg; M de Wit; Janine F M Roijers; J Hoppener; Cornelis J M Lips; Catharina Larsson; Bin Tean Teh; Hans Morreau
A genotypic and histopathological study of a large Dutch kindred with hyperparathyroidism-jaw tumor syndrome.
The Journal of clinical endocrinology and metabolism 2000;85(4):1449-54.
2000: M van der Looij; Anne-Marie Cleton-Jansen; Ronald van Eijk; Hans Morreau; Marcel van Vliet; Nel J Kuipers-Dijkshoorn; Edith Oláh; Cees J Cornelisse; Peter Devilee
A sporadic breast tumor with a somatically acquired complex genomic rearrangement in BRCA1.
Genes, chromosomes & cancer 2000;27(3):295-302.
1999: Juul Wijnen; Wiljo J F De Leeuw; H F A Vasen; Heleen van der Klift; Pål Møller; Astrid T Stormorken; Hanne Meijers-Heijboer; Dick Lindhout; Fred H Menko; Sandra Vossen; Gabriela Möslein; Carli Tops; Annette H J T Bröcker-Vriends; Y Wu; Robert M W Hofstra; Rolf Sijmons; Cees J Cornelisse; Hans Morreau; Riccardo Fodde
Familial endometrial cancer in female carriers of MSH6 germline mutations.
Nature genetics 1999;23(2):142-4.
1999: Jan W A Smit; Gabri van der Pluijm; H A Romijn; Clemens W G M Löwik; Hans Morreau; Bernard M Goslings
Degradation of extracellular matrix by metastatic follicular thyroid carcinoma cell lines: role of the plasmin activation system.
Thyroid : official journal of the American Thyroid Association 1999;9(9):913-9.
1999: Shama L van Zelderen-Bhola; R Vink; J Smit; Hans W Wessels; Hans Morreau
Translocations (X;10)(p22;q24) and (1;10)(q21;q11) in a follicular adenoma of the thyroid without apparent involvement of the RET protooncogene.
Cancer genetics and cytogenetics 1999;112(2):178-80.
1998: Jan de Boer; Jan de Wit; Harry van Steeg; Rob J W Berg; Hans Morreau; P Visser; Alan Lehmann; M Duran; Jan H J Hoeijmakers; Geert Weeda
A mouse model for the basal transcription/DNA repair syndrome trichothiodystrophy.
Molecular cell 1998;1(7):981-90.
1997: Geert Weeda; I Donker; Jan de Wit; Hans Morreau; R Janssens; C J Vissers; Alex L Nigg; Harry van Steeg; Dirk Bootsma; Jan H J Hoeijmakers
Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence.
Current biology : CB 1997;7(6):427-39.
1997: Gijsbertus T J van der Horst; Harry van Steeg; Rob J W Berg; Alain van Gool; Jan de Wit; Geert Weeda; Hans Morreau; Rudolf B Beems; Coen F van Kreijl; Frank R de Gruijl; Dirk Bootsma; Jan H J Hoeijmakers
Defective transcription-coupled repair in Cockayne syndrome B mice is associated with skin cancer predisposition.
Cell 1997;89(3):425-35.
1996: Maarten Fornerod; J Boer; Sjozef van Baal; Hans Morreau; Gerard C Grosveld
Interaction of cellular proteins with the leukemia specific fusion proteins DEK-CAN and SET-CAN and their normal counterpart, the nucleoporin CAN.
Oncogene 1996;13(8):1801-8.
1996: W Allaerts; Donna M Fluitsma; Elisabeth Hoefsmit; P H Jeucken; Hans Morreau; F T Bosman; Hemmo Drexhage
Immunohistochemical, morphological and ultrastructural resemblance between dendritic cells and folliculo-stellate cells in normal human and rat anterior pituitaries.
Journal of neuroendocrinology 1996;8(1):17-29.
1995: X Y Zhou; Hans Morreau; Robbert Rottier; D Davis; Erik J Bonten; Nynke Gillemans; D Wenger; Frank Grosveld; Peter C Doherty; K Suzuki; G C Grosveld; A d'Azzo
Mouse model for the lysosomal disorder galactosialidosis and correction of the phenotype with overexpressing erythroid precursor cells.
Genes & development 1995;9(21):2623-34.
1995: J Hikke van Doorninck; P J French; E Verbeek; R H Peters; Hans Morreau; Jan Bijman; Bob J Scholte
A mouse model for the cystic fibrosis delta F508 mutation.
The EMBO journal 1995;14(18):4403-11.
1994: A Morrone; Hans Morreau; X Y Zhou; Enrico Zammarchi; Wim J Kleijer; H Galjaard; Alessandra d'Azzo
Insertion of a T next to the donor splice site of intron 1 causes aberrantly spliced mRNA in a case of infantile GM1-gangliosidosis.
Human mutation 1994;3(2):112-20.
1992: Hans Morreau; Niels Galjart; Rob Willemsen; Nynke Gillemans; X Y Zhou; Alessandra d'Azzo
Human lysosomal protective protein. Glycosylation, intracellular transport, and association with beta-galactosidase in the endoplasmic reticulum.
The Journal of biological chemistry 1992;267(25):17949-56.
1991: Hans Morreau; Erik J Bonten; X Y Zhou; Alessandra d'Azzo
Organization of the gene encoding human lysosomal beta-galactosidase.
DNA and cell biology 1991;10(7):495-504.
1991: Niels Galjart; Hans Morreau; Rob Willemsen; Nynke Gillemans; Erik J Bonten; Alessandra d'Azzo
Human lysosomal protective protein has cathepsin A-like activity distinct from its protective function.
The Journal of biological chemistry 1991;266(22):14754-62.
1989: Hans Morreau; Niels Galjart; Nynke Gillemans; Rob Willemsen; Gijsbertus T J van der Horst; Alessandra d'Azzo
Alternative splicing of beta-galactosidase mRNA generates the classic lysosomal enzyme and a beta-galactosidase-related protein.
The Journal of biological chemistry 1989;264(34):20655-63.