Glenn Morris

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Caroline A Sewry; Ros C M Quinlivan; Waney Squier; Glenn E Morris; Ian Holt
A rapid immunohistochemical test to distinguish congenital myotonic dystrophy from X-linked myotubular myopathy.
Emma Humphrey; Heidi R Fuller; Glenn E Morris
Current research on SMN protein and treatment strategies for spinal muscular atrophy.
Le Thanh Lam; Sabrina V Böhm; Roland G Roberts; Glenn E Morris
Nesprin-2 epsilon: a novel nesprin isoform expressed in human ovary and Ntera-2 cells.

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All Publications

2012: Caroline A Sewry; Ros C M Quinlivan; Waney Squier; Glenn E Morris; Ian Holt
A rapid immunohistochemical test to distinguish congenital myotonic dystrophy from X-linked myotubular myopathy.
Neuromuscular disorders : NMD 2012;22(3):225-30.
2012: Emma Humphrey; Heidi R Fuller; Glenn E Morris
Current research on SMN protein and treatment strategies for spinal muscular atrophy.
Neuromuscular disorders : NMD 2012;22(2):193-7.
2011: Le Thanh Lam; Sabrina V Böhm; Roland G Roberts; Glenn E Morris
Nesprin-2 epsilon: a novel nesprin isoform expressed in human ovary and Ntera-2 cells.
Biochemical and biophysical research communications 2011;412(2):291-5.
2011: Ian Holt; Le Thanh Lam; Stéphanie Tomé; Derick G Wansink; Hein Te Riele; Geneviève Gourdon; Glenn E Morris
The mouse mismatch repair protein, MSH3, is a nucleoplasmic protein that aggregates into denser nuclear bodies under conditions of stress.
Journal of cellular biochemistry 2011;112(6):1612-21.
2010: Heidi R Fuller; Nguyen Thi Man; Le Thanh Lam; Vladimir A Shamanin; Elliot J Androphy; Glenn E Morris
Valproate and bone loss: iTRAQ proteomics show that valproate reduces collagens and osteonectin in SMA cells.
Journal of proteome research 2010;9(8):4228-33.
2010: K Natalie Randles; Le Thanh Lam; Caroline A Sewry; Megan Puckelwartz; Denis Furling; Manfred Wehnert; Elizabeth M McNally; Glenn E Morris
Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.
Developmental dynamics : an official publication of the American Association of Anatomists 2010;239(3):998-1009.
2010: Glenn E Morris; K Natalie Randles
Nesprin isoforms: are they inside or outside the nucleus?
Biochemical Society transactions 2010;38(Pt 1):278-80.
2010: Heidi R Fuller; Nguyen Thi Man; Le Thanh Lam; Le Thiet Thanh; Rebecca A Keough; Arndt Asperger; Thomas J Gonda; Glenn E Morris
The SMN interactome includes Myb-binding protein 1a.
Journal of proteome research 2010;9(1):556-63.
2009: Ian Holt; Virginie Jacquemin; Majid Fardaei; Caroline A Sewry; Gillian S Butler-Browne; Denis Furling; J David Brook; Glenn E Morris
Muscleblind-like proteins: similarities and differences in normal and myotonic dystrophy muscle.
The American journal of pathology 2009;174(1):216-27.
2008: Nguyen thi Man; E Humphrey; L T Lam; H R Fuller; T A Lynch; C A Sewry; P R Goodwin; A E Mackenzie; G E Morris
A two-site ELISA can quantify upregulation of SMN protein by drugs for spinal muscular atrophy.
Neurology 2008;71(22):1757-63.
2008: Glenn E Morris
The Cajal body.
Biochimica et biophysica acta 2008;1783(11):2108-15.
2008: Tatiana O Gavrilina; Vicki L McGovern; Eileen Workman; Thomas O Crawford; Rocky G Gogliotti; Christine J DiDonato; Umrao R Monani; Glenn E Morris; Arthur H M Burghes
Neuronal SMN expression corrects spinal muscular atrophy in severe SMA mice while muscle-specific SMN expression has no phenotypic effect.
Human molecular genetics 2008;17(8):1063-75.
2007: Ian Holt; Saloni Mittal; Denis Furling; Gillian S Butler-Browne; J David Brook; Glenn E Morris
Defective mRNA in myotonic dystrophy accumulates at the periphery of nuclear splicing speckles.
Genes to cells : devoted to molecular & cellular mechanisms 2007;12(9):1035-48.
2007: Elizabeth C Wolstencroft; Goran Simic; Nguyen thi Man; Ian Holt; Le Thanh Lam; Paul R Buckland; Glenn E Morris
Endosomal location of dopamine receptors in neuronal cell cytoplasm.
Journal of molecular histology 2007;38(4):333-40.
2007: Le thi Hao; Heidi R Fuller; Le Thanh Lam; Thanh T Le; Arthur H M Burghes; Glenn E Morris
Absence of gemin5 from SMN complexes in nuclear Cajal bodies.
BMC cell biology 2007;8():28.
2005: Aarti Sharma; Anja Lambrechts; Le Thi Hao; Thanh T Le; Caroline A Sewry; Christophe Ampe; Arthur H M Burghes; Glenn E Morris
A role for complexes of survival of motor neurons (SMN) protein with gemins and profilin in neurite-like cytoplasmic extensions of cultured nerve cells.
Experimental cell research 2005;309(1):185-97.
2005: Y Chan N Pham; Nguyen thi Man; Ian Holt; Caroline A Sewry; Gurman Pall; Keith Johnson; Glenn E Morris
Characterisation of the transcription factor, SIX5, using a new panel of monoclonal antibodies.
Journal of cellular biochemistry 2005;95(5):990-1001.
2005: Glenn E Morris
Epitope mapping.
Methods in molecular biology (Clifton, N.J.) 2005;295():255-68.
2004: Norma B Romero; Serge Braun; Olivier Benveniste; France Leturcq; Jean-Yves Hogrel; Glenn E Morris; Annie Barois; Bruno Eymard; Christine Payan; Véronique Ortega; et al.
Phase I study of dystrophin plasmid-based gene therapy in Duchenne/Becker muscular dystrophy.
Human gene therapy 2004;15(11):1065-76.
2004: Mitchell R Lunn; David E Root; Allison M Martino; Stephen P Flaherty; Brian P Kelley; Daniel D Coovert; Arthur H Burghes; Nguyen Thi Man; Glenn E Morris; Jianhua Zhou; et al.
Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism.
Chemistry & biology 2004;11(11):1489-93.
2004: Jean-Francois Masson; Margaret Barnhart; Tina M Battaglia; Glenn E Morris; Ronald A Nieman; Philip J Young; Christian L Lorson; Karl S Booksh
Monitoring of recombinant survival motor neuron protein using fiber-optic surface plasmon resonance.
The Analyst 2004;129(9):855-9.
2004: Sushila Manilal; K Natalie Randles; Christelle Aunac; Man thi Nguyen; Glenn E Morris
A lamin A/C beta-strand containing the site of lipodystrophy mutations is a major surface epitope for a new panel of monoclonal antibodies.
Biochimica et biophysica acta 2004;1671(1-3):87-92.
2004: Glenn E Morris
Protein interactions, right or wrong, in Emery-Dreifuss muscular dystrophy.
Symposia of the Society for Experimental Biology 2004;(56):57-68.
2003: Qi Long Lu; Christopher J Mann; Fang Lou; George Bou-Gharios; Glenn E Morris; Shao-an Xue; Sue Fletcher; Terence A Partridge; Stephen D Wilton
Functional amounts of dystrophin produced by skipping the mutated exon in the mdx dystrophic mouse.
Nature medicine 2003;9(8):1009-14.
2003: Ian Holt; Cecilia Ostlund; Colin L Stewart; Nguyen thi Man; Howard J Worman; Glenn E Morris
Effect of pathogenic mis-sense mutations in lamin A on its interaction with emerin in vivo.
Journal of cell science 2003;116(Pt 14):3027-35.
2003: Fiona L Wilkinson; James M Holaska; Zhayi Zhang; Aarti Sharma; Sushila Manilal; Ian Holt; Stefan Stamm; Katherine L Wilson; Glenn E Morris
Emerin interacts in vitro with the splicing-associated factor, YT521-B.
European journal of biochemistry / FEBS 2003;270(11):2459-66.
2003: Denis Furling; Le Thanh Lam; Onnik Agbulut; Gillian S Butler-Browne; Glenn E Morris
Changes in myotonic dystrophy protein kinase levels and muscle development in congenital myotonic dystrophy.
The American journal of pathology 2003;162(3):1001-9.
2002: Gisèle Bonne; Jaqueline Capeau; Marianne De Visser; Denis Duboc; Luciano Merlini; Glenn E Morris; Francesco Muntoni; Dominique Recan; Caroline Sewry; Stefano Squarzoni; et al.
82nd ENMC international workshop, 5th international Emery-Dreifuss muscular dystrophy (EDMD) workshop, 1st Workshop of the MYO-CLUSTER project EUROMEN (European muscle envelope nucleopathies), 15-16 September 2000, Naarden, The Netherlands.
Neuromuscular disorders : NMD 2002;12(2):187-94.
2002: Philip J Young; Patricia M Day; Jianhua Zhou; Elliot J Androphy; Glenn E Morris; Christian L Lorson
A direct interaction between the survival motor neuron protein and p53 and its relationship to spinal muscular atrophy.
The Journal of biological chemistry 2002;277(4):2852-9.
2002: J Colomer; C Iturriaga; G Bonne; K Schwartz; S Manilal; G E Morris; M Puche; E Fernández-Alvarez
Autosomal dominant Emery-Dreifuss muscular dystrophy: a new family with late diagnosis.
Neuromuscular disorders : NMD 2002;12(1):19-25.
2001: I Holt; L Clements; S Manilal; G E Morris
How does a g993t mutation in the emerin gene cause Emery-Dreifuss muscular dystrophy?
Biochemical and biophysical research communications 2001;287(5):1129-33.
2001: S P Chambers; A Dodd; R Overall; T Sirey; L T Lam; G E Morris; D R Love
Dystrophin in adult zebrafish muscle.
Biochemical and biophysical research communications 2001;286(3):478-83.
2001: A V Pereboev; N Ahmed; N thi Man; G E Morris
Epitopes in the interacting regions of beta-dystroglycan (PPxY motif) and dystrophin (WW domain).
Biochimica et biophysica acta 2001;1527(1-2):54-60.
2001: P J Young; T T Le; M Dunckley; T M Nguyen; A H Burghes; G E Morris
Nuclear gems and Cajal (coiled) bodies in fetal tissues: nucleolar distribution of the spinal muscular atrophy protein, SMN.
Experimental cell research 2001;265(2):252-61.
2001: I Holt; L Clements; S Manilal; S C Brown; G E Morris
The R482Q lamin A/C mutation that causes lipodystrophy does not prevent nuclear targeting of lamin A in adipocytes or its interaction with emerin.
European journal of human genetics : EJHG 2001;9(3):204-8.
2001: C A Sewry; N T Man; T Lynch; G E Morris
Absence of utrophin in intercalated discs of human cardiac muscle.
The Histochemical journal 2001;33(1):9-12.
2000: P J Young; N T Man; C L Lorson; T T Le; E J Androphy; A H Burghes; G E Morris
The exon 2b region of the spinal muscular atrophy protein, SMN, is involved in self-association and SIP1 binding.
Human molecular genetics 2000;9(19):2869-77.
2000: T T Le; D D Coovert; U R Monani; G E Morris; A H Burghes
The survival motor neuron (SMN) protein: effect of exon loss and mutation on protein localization.
Neurogenetics 2000;3(1):7-16.
2000: L T Lam; Y C Pham; T M Nguyen; G E Morris
Characterization of a monoclonal antibody panel shows that the myotonic dystrophy protein kinase, DMPK, is expressed almost exclusively in muscle and heart.
Human molecular genetics 2000;9(14):2167-73.
2000: D D Coovert; T T Le; G E Morris; N T Man; M Kralewski; M Sendtner; A H Burghes
Does the survival motor neuron protein (SMN) interact with Bcl-2?
Journal of medical genetics 2000;37(7):536-9.
2000: R J Bartlett; S Stockinger; M M Denis; W T Bartlett; L Inverardi; T T Le; N thi Man; G E Morris; D J Bogan; J Metcalf-Bogan; et al.
In vivo targeted repair of a point mutation in the canine dystrophin gene by a chimeric RNA/DNA oligonucleotide.
Nature biotechnology 2000;18(6):615-22.
2000: P J Young; T T Le; N thi Man; A H Burghes; G E Morris
The relationship between SMN, the spinal muscular atrophy protein, and nuclear coiled bodies in differentiated tissues and cultured cells.
Experimental cell research 2000;256(2):365-74.
2000: Q L Lu; G E Morris; S D Wilton; T Ly; O V Artem'yeva; P Strong; T A Partridge
Massive idiosyncratic exon skipping corrects the nonsense mutation in dystrophic mouse muscle and produces functional revertant fibers by clonal expansion.
The Journal of cell biology 2000;148(5):985-96.
2000: U R Monani; M Sendtner; D D Coovert; D W Parsons; C Andreassi; T T Le; S Jablonka; B Schrank; W Rossoll; W Rossol; et al.
The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy.
Human molecular genetics 2000;9(3):333-9.
2000: L A Pereboeva; A V Pereboev; L F Wang; G E Morris
Hepatitis C epitopes from phage-displayed cDNA libraries and improved diagnosis with a chimeric antigen.
Journal of medical virology 2000;60(2):144-51.
2000: L Clements; S Manilal; D R Love; G E Morris
Direct interaction between emerin and lamin A.
Biochemical and biophysical research communications 2000;267(3):709-14.
1999: S J Schatzberg; N J Olby; M Breen; L V Anderson; C F Langford; H F Dickens; S D Wilton; C J Zeiss; M M Binns; J N Kornegay; et al.
Molecular analysis of a spontaneous dystrophin 'knockout' dog.
Neuromuscular disorders : NMD 1999;9(5):289-95.
1999: F L Wilkinson; T M Nguyen; S B Manilal; P Thomas; J W Neal; P S Harper; A L Jones; G E Morris
Localization of rabbit huntingtin using a new panel of monoclonal antibodies.
Brain research. Molecular brain research 1999;69(1):10-20.
1999: S Manilal; C A Sewry; A Pereboev; N Man; P Gobbi; S Hawkes; D R Love; G E Morris
Distribution of emerin and lamins in the heart and implications for Emery-Dreifuss muscular dystrophy.
Human molecular genetics 1999;8(2):353-9.
1999: G E Morris; S Manilal
Heart to heart: from nuclear proteins to Emery-Dreifuss muscular dystrophy.
Human molecular genetics 1999;8(10):1847-51.
1999: G E Morris; T M Nguyen; T N Nguyen; A Pereboev; J Kendrick-Jones; S J Winder
Disruption of the utrophin-actin interaction by monoclonal antibodies and prediction of an actin-binding surface of utrophin.
The Biochemical journal 1999;337 ( Pt 1)():119-23.
1998: Y C Pham; N Man; L T Lam; G E Morris
Localization of myotonic dystrophy protein kinase in human and rabbit tissues using a new panel of monoclonal antibodies.
Human molecular genetics 1998;7(12):1957-65.
1998: L A Pereboeva; A V Pereboev; G E Morris
Identification of antigenic sites on three hepatitis C virus proteins using phage-displayed peptide libraries.
Journal of medical virology 1998;56(2):105-11.
1998: S Manilal; T M Nguyen; G E Morris
Colocalization of emerin and lamins in interphase nuclei and changes during mitosis.
Biochemical and biophysical research communications 1998;249(3):643-7.
1998: G E Morris; S G Sedgwick; J M Ellis; A Pereboev; J S Chamberlain; Nguyen thi Man
An epitope structure for the C-terminal domain of dystrophin and utrophin.
Biochemistry 1998;37(31):11117-27.
1998: N Ahmed; T M Nguyen; G E Morris
Flexible hinges in dystrophin.
Biochemical Society transactions 1998;26(3):S310.
1998: P Thomas; F Wilkinson; T M Nguyen; P S Harper; J W Neal; G E Morris; A L Jones
Full length huntingtin is not detected in intranuclear inclusions in Huntington's disease brain.
Biochemical Society transactions 1998;26(3):S243.
1998: S Manilal; D Recan; C A Sewry; M Hoeltzenbein; S Llense; F Leturcq; N Deburgrave; J Barbot; N Man; F Muntoni; et al.
Mutations in Emery-Dreifuss muscular dystrophy and their effects on emerin protein expression.
Human molecular genetics 1998;7(5):855-64.
1998: F Muntoni; E J Lichtarowicz-Krynska; C A Sewry; S Manilal; D Recan; S Llense; J Taylor; G E Morris; V Dubowitz
Early presentation of X-linked Emery-Dreifuss muscular dystrophy resembling limb-girdle muscular dystrophy.
Neuromuscular disorders : NMD 1998;8(2):72-6.
1997: G E Morris
Dystrophin is replaced by utrophin in frog heart; implications for muscular dystrophy.
Neuromuscular disorders : NMD 1997;7(8):493-8.
1997: N H Nguyen; V B Tran; G E Morris
Nucleotide sequences from the capsid and pre-protein regions of dengue viruses from VietNam.
Biochemical Society transactions 1997;25(1):54S.
1997: F Wilkinson; T M Nguyen; G E Morris
Monoclonal antibodies from three new regions of huntingtin, the Huntington's disease protein.
Biochemical Society transactions 1997;25(1):51S.
1997: S Manilal; C A Sewry; N Man; F Muntoni; G E Morris
Diagnosis of X-linked Emery-Dreifuss muscular dystrophy by protein analysis of leucocytes and skin with monoclonal antibodies.
Neuromuscular disorders : NMD 1997;7(1):63-6.
1997: T Webb; P J Jackson; G E Morris
Protease digestion studies of an equilibrium intermediate in the unfolding of creatine kinase.
The Biochemical journal 1997;321 ( Pt 1)():83-8.
1996: S Manilal; T M Nguyen; C A Sewry; G E Morris
The Emery-Dreifuss muscular dystrophy protein, emerin, is a nuclear membrane protein.
Human molecular genetics 1996;5(6):801-8.
1996: M James; T M Nguyen; C J Wise; G E Jones; G E Morris
Utrophin-dystroglycan complex in membranes of adherent cultured cells.
Cell motility and the cytoskeleton 1996;33(3):163-74.
1995: G E Morris; C Simmons; T M Nguyen
Apo-dystrophins (Dp140 and Dp71) and dystrophin splicing isoforms in developing brain.
Biochemical and biophysical research communications 1995;215(1):361-7.
1995: Le Thiet Thanh; Nguyen Thi Man; S Hori; C A Sewry; V Dubowitz; G E Morris
Characterization of genetic deletions in Becker muscular dystrophy using monoclonal antibodies against a deletion-prone region of dystrophin.
American journal of medical genetics 1995;58(2):177-86.
1995: M James; C Simmons; C J Wise; G E Jones; G E Morris
Evidence for a utrophin-glycoprotein complex in cultured cell lines and a possible role in cell adhesion.
Biochemical Society transactions 1995;23(3):398S.
1995: T M Nguyen; T R Helliwell; C Simmons; S J Winder; J Kendrick-Jones; K E Davies; G E Morris
Full-length and short forms of utrophin, the dystrophin-related protein.
FEBS letters 1995;358(3):262-6.
1993: A Clerk; G E Morris; V Dubowitz; K E Davies; C A Sewry
Dystrophin-related protein, utrophin, in normal and dystrophic human fetal skeletal muscle.
The Histochemical journal 1993;25(8):554-61.