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Alexandre Morrot

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Ana Flávia F R Nardy; Luciana Penha; Ana Rosa Pérez; Ana Acacia S Pinheiro; Wilson Savino; Christina Maeda Takiya; Adriane R Todeschini; Maria Bellio; Oscar Bottasso; Celso Caruso-Neves; Isadora de Araújo Oliveira; Juliana de Meis; Wagner B Dias; Désio Aurélio Farias-de-Oliveira; Celio G Freire-De-Lima; João Luiz da Silva Filho; Alexandre Morrot
Trans-sialidase from Trypanosoma cruzi enhances the adhesion properties and fibronectin-driven migration of thymocytes.
Marcelo de Carvalho Filgueiras; Alexandre Morrot; Pedro Marcos Gomes Soares; Manoel L Costa; Cláudia S Mermelstein
Effects of 5-Fluorouracil in nuclear and cellular morphology, proliferation, cell cycle, apoptosis, cytoskeletal and caveolar distribution in primary cultures of smooth muscle cells.
João Luiz Silva-Filho; Mariana Conceição Souza; Wilson Savino; Leandro Souza Silva; Celso Caruso-Neves; Maria Fernanda Souza Costa; Claudio Teixeira Ferreira-Dasilva; Maria das Graças Henriques; Alexandre Morrot; Tatiana Almeida Padua; Ana Acacia S Pinheiro
Angiotensin II Is a New Component Involved in Splenic T Lymphocyte Responses during Plasmodium berghei ANKA Infection.

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All Publications

2013: Ana Flávia F R Nardy; Luciana Penha; Ana Rosa Pérez; Ana Acacia S Pinheiro; Wilson Savino; Christina Maeda Takiya; Adriane R Todeschini; Maria Bellio; Oscar Bottasso; Celso Caruso-Neves; Isadora de Araújo Oliveira; Juliana de Meis; Wagner B Dias; Désio Aurélio Farias-de-Oliveira; Celio G Freire-De-Lima; João Luiz da Silva Filho; Alexandre Morrot
Trans-sialidase from Trypanosoma cruzi enhances the adhesion properties and fibronectin-driven migration of thymocytes.
Microbes and infection / Institut Pasteur 2013;15(5):365-74.
2013: Marcelo de Carvalho Filgueiras; Alexandre Morrot; Pedro Marcos Gomes Soares; Manoel L Costa; Cláudia S Mermelstein
Effects of 5-Fluorouracil in nuclear and cellular morphology, proliferation, cell cycle, apoptosis, cytoskeletal and caveolar distribution in primary cultures of smooth muscle cells.
PloS one 2013;8(4):e63177.
2013: João Luiz Silva-Filho; Mariana Conceição Souza; Wilson Savino; Leandro Souza Silva; Celso Caruso-Neves; Maria Fernanda Souza Costa; Claudio Teixeira Ferreira-Dasilva; Maria das Graças Henriques; Alexandre Morrot; Tatiana Almeida Padua; Ana Acacia S Pinheiro
Angiotensin II Is a New Component Involved in Splenic T Lymphocyte Responses during Plasmodium berghei ANKA Infection.
PloS one 2013;8(4):e62999.
2012: Débora M Portilho; Wilson Savino; Carolina P Soares; Leandro S Thiago; Gillian Butler-Browne; Manoel L Costa; Alexandre Morrot; Cláudia S Mermelstein
Cholesterol depletion by methyl-β-cyclodextrin enhances cell proliferation and increases the number of desmin-positive cells in myoblast cultures.
European journal of pharmacology 2012;694(1-3):1-12.
2012: Ailin Lepletier; Alexandre Morrot; Vinícius de Frias Carvalho; Wilson Savino
Thymic atrophy in acute experimental Chagas disease is associated with an imbalance of stress hormones.
Annals of the New York Academy of Sciences 2012;1262():45-50.
2012: Ana Rosa Pérez; Luiz R Berbert; Alexandre Morrot; Eugenia Terra-Granado; Wilson Savino
Extrathymic CD4+CD8+ lymphocytes in Chagas disease: possible relationship with an immunoendocrine imbalance.
Annals of the New York Academy of Sciences 2012;1262():27-36.
2012: Dirlei Nico; Marcos Palatnik; Daniel Ferreira Feijó; Naiara Maran; Alexandre Morrot; Julio Scharfstein; Clarisa Beatriz Palatnik de Sousa
Resistance to visceral leishmaniasis is severely compromised in mice deficient of bradykinin B2-receptors.
Parasites & vectors 2012;5():261.
2012: Juliana de Meis; Naiara Maran; Alexandre Morrot; Pedro H Nunes Panzenhagen; Désio Aurélio Farias-de-Oliveira; Déa Maria Serra Villa-Verde; Wilson Savino
Thymus atrophy and double-positive escape are common features in infectious diseases.
Journal of parasitology research 2012;2012():574020.
2012: Alexandre Morrot; Juliana Barreto de Albuquerque; Luiz Ricardo Berbert; Carla Eponina de Carvalho Pinto; Juliana de Meis; Wilson Savino
Dynamics of Lymphocyte Populations during Trypanosoma cruzi Infection: From Thymocyte Depletion to Differential Cell Expansion/Contraction in Peripheral Lymphoid Organs.
Journal of tropical medicine 2012;2012():747185.
2011: João Luiz Silva-Filho; Mariana Conceição Souza; Wilson Savino; Celso Caruso-Neves; Maria das Graças Henriques; Alexandre Morrot; Marise Pinheiro Nunes; Ana Acacia S Pinheiro
AT1 receptor-mediated angiotensin II activation and chemotaxis of T lymphocytes.
Molecular immunology 2011;48(15-16):1835-43.
2011: Alexandre Morrot; Ana Rosa Pérez; Pärt Peterson; Juan Beloscar; Luiz Ricardo Berbert; Oscar Bottasso; Juliana de Meis; Désio Aurélio Farias-de-Oliveira; Vivian Kont; Novica M Milićević; Suse Dayse Silva-Barbosa; Christina Maeda Takiya; Eugênia Terra-Granado; Xiaoping Wang; Wilson Savino
Chagasic thymic atrophy does not affect negative selection but results in the export of activated CD4+CD8+ T cells in severe forms of human disease.
PLoS neglected tropical diseases 2011;5(8):e1268.
2009: Juliana de Meis; Alexandre Morrot; Désio Aurélio Farias-de-Oliveira; Déa Maria Serra Villa-Verde; Wilson Savino
Differential regional immune response in Chagas disease.
PLoS neglected tropical diseases 2009;3(7):e417.
2008: Sarat K Dalai; Saied Mirshahidi; Alexandre Morrot; Fidel Zavala; Scheherazade Sadegh-Nasseri
Anergy in memory CD4+ T cells is induced by B cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(5):3221-31.
2007: Ana Carolina Monteiro; Verônica Schmitz; Alexandre Morrot; Luciana Barros de Arruda; Fnu Nagajyothi; Alessandra Granato; João B Pesquero; Werner Müller-Esterl; Herbert B Tanowitz; Julio Scharfstein
Bradykinin B2 Receptors of dendritic cells, acting as sensors of kinins proteolytically released by Trypanosoma cruzi, are critical for the development of protective type-1 responses.
PLoS pathogens 2007;3(11):e185.
2007: Ana Acacia de Sa Pinheiro; Alexandre Morrot; Sumana Chakravarty; Michael Overstreet; Jay H Bream; Pablo M Irusta; Fidel Zavala
IL-4 induces a wide-spectrum intracellular signaling cascade in CD8+ T cells.
Journal of leukocyte biology 2007;81(4):1102-10.
2006: Ana Carolina Monteiro; Verônica Schmitz; Erik Svensjö; Ricardo T Gazzinelli; Igor Almeida; Alex G Todorov; Luciana Barros de Arruda; Ana Cláudia T Torrecilhas; João B Pesquero; Alexandre Morrot; Eliete Bouskela; Adriana Bonomo; Ana Paula C A Lima; Werner Müller-Esterl; Julio Scharfstein
Cooperative activation of TLR2 and bradykinin B2 receptor is required for induction of type 1 immunity in a mouse model of subcutaneous infection by Trypanosoma cruzi.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(9):6325-35.
2006: Sylvie Bertholet; Romina S Goldszmid; Alexandre Morrot; Alain Debrabant; Farhat Afrin; Carmen M Collazo-Custodio; Mathieu Houde; Michel Desjardins; Alan Sher; David Sacks
Leishmania antigens are presented to CD8+ T cells by a transporter associated with antigen processing-independent pathway in vitro and in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(6):3525-33.
2006: Julius Hafalla; Urvashi Rai; Alexandre Morrot; Dabeiba Bernal-Rubio; Fidel Zavala; Ana Rodriguez
Priming of CD8+ T cell responses following immunization with heat-killed Plasmodium sporozoites.
European journal of immunology 2006;36(5):1179-86.
2006: Alexandre Morrot; Ian A Cockburn; Michael Overstreet; Dolores Rodríguez; Fidel Zavala
Protective CD8+ T cells induced by malaria sporozoites do not undergo modulation of interleukin-7 receptor expression.
Infection and immunity 2006;74(4):2495-7.
2006: Silvia B Boscardin; Julius Hafalla; Revati F Masilamani; Alice O Kamphorst; Henry A Zebroski; Urvashi Rai; Alexandre Morrot; Fidel Zavala; Ralph M Steinman; Ruth S Nussenzweig; Michel C Nussenzweig
Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses.
The Journal of experimental medicine 2006;203(3):599-606.
2005: Alexandre Morrot; Julius Hafalla; Ian A Cockburn; Luzia Carvalho; Fidel Zavala
IL-4 receptor expression on CD8+ T cells is required for the development of protective memory responses against liver stages of malaria parasites.
The Journal of experimental medicine 2005;202(4):551-60.
2004: Alexandre Morrot; Fidel Zavala
Regulation of the CD8+ T cell responses against Plasmodium liver stages in mice.
International journal for parasitology 2004;34(13-14):1529-34.
2004: Alexandre Morrot; Fidel Zavala
Effector and memory CD8+ T cells as seen in immunity to malaria.
Immunological reviews 2004;201():291-303.
2003: Julius Hafalla; Alexandre Morrot; Gen-Ichiro Sano; Geneviève Milon; Juan J Lafaille; Fidel Zavala
Early self-regulatory mechanisms control the magnitude of CD8+ T cell responses against liver stages of murine malaria.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):964-70.
2002: Julius Hafalla; Gen-Ichiro Sano; Luzia Carvalho; Alexandre Morrot; Fidel Zavala
Short-term antigen presentation and single clonal burst limit the magnitude of the CD8(+) T cell responses to malaria liver stages.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(18):11819-24.
2002: Luzia Carvalho; Gen-Ichiro Sano; Julius Hafalla; Alexandre Morrot; Maria A Curotto de Lafaille; Fidel Zavala
IL-4-secreting CD4+ T cells are crucial to the development of CD8+ T-cell responses against malaria liver stages.
Nature medicine 2002;8(2):166-70.
2001: Gen-Ichiro Sano; Julius Hafalla; Alexandre Morrot; R Abe; Juan J Lafaille; Fidel Zavala
Swift development of protective effector functions in naive CD8(+) T cells against malaria liver stages.
The Journal of experimental medicine 2001;194(2):173-80.
2000: Julio Scharfstein; Verônica Schmitz; V Morandi; M M Capella; Ana Paula C A Lima; Alexandre Morrot; Luiz Juliano; Werner Müller-Esterl
Host cell invasion by Trypanosoma cruzi is potentiated by activation of bradykinin B(2) receptors.
The Journal of experimental medicine 2000;192(9):1289-300.
1999: Julio Scharfstein; Alexandre Morrot
A role for extracellular amastigotes in the immunopathology of Chagas disease.
Memórias do Instituto Oswaldo Cruz 1999;94 Suppl 1():51-63.
1997: Alexandre Morrot; Dudley K Strickland; M de L Higuchi; M Reis; R Pedrosa; Julio Scharfstein
Human T cell responses against the major cysteine proteinase (cruzipain) of Trypanosoma cruzi: role of the multifunctional alpha 2-macroglobulin receptor in antigen presentation by monocytes.
International immunology 1997;9(6):825-34.