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Casey Morrow

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TOP 3
Peter G Eipers; Jesus F Salazar-Gonzalez; Casey D Morrow
HIV gene expression from intact proviruses positioned in bacterial artificial chromosomes at integration sites previously identified in latently infected T cells.
Maureen C Kelly; Barry R Kosloff; Casey D Morrow
Forced selection of tRNA(Glu) reveals the importance of two adenosine-rich RNA loops within the U5-PBS for SIV(smmPBj) replication.
Anna McCulley; Casey D Morrow
Nucleotides within the anticodon stem are important for optimal use of tRNA(Lys,3) as the primer for HIV-1 reverse transcription.

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All Publications

2011: Peter G Eipers; Jesus F Salazar-Gonzalez; Casey D Morrow
HIV gene expression from intact proviruses positioned in bacterial artificial chromosomes at integration sites previously identified in latently infected T cells.
Virology 2011;410(1):151-60.
2007: Maureen C Kelly; Barry R Kosloff; Casey D Morrow
Forced selection of tRNA(Glu) reveals the importance of two adenosine-rich RNA loops within the U5-PBS for SIV(smmPBj) replication.
Virology 2007;366(2):330-9.
2007: Anna McCulley; Casey D Morrow
Nucleotides within the anticodon stem are important for optimal use of tRNA(Lys,3) as the primer for HIV-1 reverse transcription.
Virology 2007;364(1):169-77.
2007: Matthew T Palmer; Richard L Kirkman; Barry R Kosloff; Peter G Eipers; Casey D Morrow
tRNA isoacceptor preference prior to retrovirus Gag-Pol junction links primer selection and viral translation.
Journal of virology 2007;81(9):4397-404.
2007: Na Ni; Casey D Morrow
Impact of forced selection of tRNAs on HIV-1 replication and genome stability highlight preferences for selection of certain tRNAs.
Virus research 2007;124(1-2):29-37.
2007: Uros V Djekic; Casey D Morrow
Analysis of the replication of HIV-1 forced to use tRNAMet(i) supports a link between primer selection, translation and encapsidation.
Retrovirology 2007;4():10.
2007: Wanfeng Yu; Anna McCulley; Casey D Morrow
Mutations in the TPsiC loop of E. coli tRNALys,3 have varied effects on in trans complementation of HIV-1 replication.
Virology journal 2007;4():5.
2007: Na Ni; Wenqin Xu; Casey D Morrow
Importance of A-loop complementarity with tRNAHis anticodon for continued selection of tRNAHis as the HIV reverse transcription primer.
Virology journal 2007;4():4.
2006: Anna McCulley; Casey D Morrow
Complementation of human immunodeficiency virus type 1 replication by intracellular selection of Escherichia coli formula supplied in trans.
Journal of virology 2006;80(19):9641-50.
2006: Wenqin Xu; Casey D Morrow
The G490E mutation in reverse transcriptase does not impact tRNA primer selection by HIV-1 with altered PBS and A-loop.
Virology 2006;352(2):380-9.
2006: Meng Li; Peter G Eipers; Na Ni; Casey D Morrow
HIV-1 designed to use different tRNAGln isoacceptors prefers to select tRNAThr for replication.
Virology journal 2006;3():80.
2005: Cheryl A Jackson; Jeffery Messinger; Jean D Peduzzi-Nelson; David C Ansardi; Casey D Morrow
Enhanced functional recovery from spinal cord injury following intrathecal or intramuscular administration of poliovirus replicons encoding IL-10.
Virology 2005;336(2):173-83.
2005: Nathan J Kelly; Casey D Morrow
Structural elements of the tRNA TPsiC loop critical for nucleocytoplasmic transport are important for human immunodeficiency virus type 1 primer selection.
Journal of virology 2005;79(10):6532-9.
2005: Matthew T Palmer; Sylvia A McPherson; Casey D Morrow
Murine leukemia virus with a primer-binding site complementary to tRNALys,3 adapts to select new tRNAs for replication following extended in vitro culture.
Virology 2005;333(2):337-48.
2005: Lesley E Smythies; Miroslav J Novak; Ken B Waites; J Russell Lindsey; Casey D Morrow; Phillip D Smith
Poliovirus replicons encoding the B subunit of Helicobacter pylori urease protect mice against H. pylori infection.
Vaccine 2005;23(7):901-9.
2005: Kenda L Moore-Rigdon; Barry R Kosloff; Richard L Kirkman; Casey D Morrow
Preferences for the selection of unique tRNA primers revealed from analysis of HIV-1 replication in peripheral blood mononuclear cells.
Retrovirology 2005;2():21.
2004: Wenlong Han; Megan Wind-Rotolo; Richard L Kirkman; Casey D Morrow
Inhibition of human immunodeficiency virus type 1 replication by siRNA targeted to the highly conserved primer binding site.
Virology 2004;330(1):221-32.
2004: Matthew T Palmer; Casey D Morrow
Analysis of murine leukemia virus replication complemented by yeast tRNA(Phe) reveals inherent preferences for the tRNA primer selected for reverse transcription.
Virology 2004;324(2):430-8.
2004: Kenda L Moore; Barry R Kosloff; Nathan J Kelly; Richard L Kirkman; Lesley C Dupuy; Sylvia A McPherson; Casey D Morrow
HIV type 1 that select tRNA(His) or tRNA(Lys1,2) as primers for reverse transcription exhibit different infectivities in peripheral blood mononuclear cells.
AIDS research and human retroviruses 2004;20(4):373-81.
2003: Patricia N Fultz; Jackie Stallworth; Donna Porter; Miroslav Novak; Marie J Anderson; Casey D Morrow
Immunogenicity in pig-tailed macaques of poliovirus replicons expressing HIV-1 and SIV antigens and protection against SHIV-89.6P disease.
Virology 2003;315(2):425-37.
2003: Mickaël Rigourd; Valérie Goldschmidt; Fabienne Brulé; Casey D Morrow; Bernard Ehresmann; Chantal Ehresmann; Roland Marquet
Structure-function relationships of the initiation complex of HIV-1 reverse transcription: the case of mutant viruses using tRNA(His) as primer.
Nucleic acids research 2003;31(19):5764-75.
2003: Cheryl A Jackson; Jeff Messinger; Matthew T Palmer; Jean D Peduzzi-Nelson; Casey D Morrow
Gene expression in the muscle and central nervous system following intramuscular inoculation of encapsidated or naked poliovirus replicons.
Virology 2003;314(1):45-61.
2003: Nathan J Kelly; Casey D Morrow
Yeast tRNA(Phe) expressed in human cells can be selected by HIV-1 for use as a reverse transcription primer.
Virology 2003;313(2):354-63.
2003: Lesley C Dupuy; Nathan J Kelly; Tricia E Elgavish; Stephen C Harvey; Casey D Morrow
Probing the importance of tRNA anticodon: human immunodeficiency virus type 1 (HIV-1) RNA genome complementarity with an HIV-1 that selects tRNA(Glu) for replication.
Journal of virology 2003;77(16):8756-64.
2003: Nathan J Kelly; Matthew T Palmer; Casey D Morrow
Selection of retroviral reverse transcription primer is coordinated with tRNA biogenesis.
Journal of virology 2003;77(16):8695-701.
2003: Miroslav J Novak; Zina Moldoveanu; Wen-Qiang Huang; Cheryl A Jackson; Matthew T Palmer; Sylvia A McPherson; Casey D Morrow
Intramuscular immunization with poliovirus replicons primes for a humoral and cellular immune response to soluble antigen.
Viral immunology 2003;16(2):169-82.
2001: David C Ansardi; DC Porter; Cheryl A Jackson; G Y Gillespie; Casey D Morrow
RNA replicons derived from poliovirus are directly oncolytic for human tumor cells of diverse origins.
Cancer research 2001;61(23):8470-9.
2001: Cheryl A Jackson; C Glenn Cobbs; Jean D Peduzzi-Nelson; M Novak; Casey D Morrow
Repetitive intrathecal injections of poliovirus replicons result in gene expression in neurons of the central nervous system without pathogenesis.
Human gene therapy 2001;12(15):1827-41.
2001: Qin Yu; Casey D Morrow
Identification of critical elements in the tRNA acceptor stem and T(Psi)C loop necessary for human immunodeficiency virus type 1 infectivity.
Journal of virology 2001;75(10):4902-6.
2000: Qin Yu; Casey D Morrow
Essential regions of the tRNA primer required for HIV-1 infectivity.
Nucleic acids research 2000;28(23):4783-9.
2000: A W Bledsoe; Cheryl A Jackson; Sylvia A McPherson; Casey D Morrow
Cytokine production in motor neurons by poliovirus replicon vector gene delivery.
Nature biotechnology 2000;18(9):964-9.
2000: L K Johansen; Casey D Morrow
Inherent instability of poliovirus genomes containing two internal ribosome entry site (IRES) elements supports a role for the IRES in encapsidation.
Journal of virology 2000;74(18):8335-42.
2000: L K Johansen; Casey D Morrow
The RNA encompassing the internal ribosome entry site in the poliovirus 5' nontranslated region enhances the encapsidation of genomic RNA.
Virology 2000;273(2):391-9.
2000: A W Bledsoe; G Yancey Gillespie; Casey D Morrow
Targeted foreign gene expression in spinal cord neurons using poliovirus replicons.
Journal of neurovirology 2000;6(2):95-105.
1999: Miroslav J Novak; Lesley E Smythies; Sylvia A McPherson; Phillip D Smith; Casey D Morrow
Poliovirus replicons encoding the B subunit of Helicobacter pylori urease elicit a Th1 associated immune response.
Vaccine 1999;17(19):2384-91.
1999: SM Kang; Z Zhang; Casey D Morrow
Identification of a human immunodeficiency virus type 1 that stably uses tRNALys1,2 rather than tRNALys,3 for initiation of reverse transcription.
Virology 1999;257(1):95-105.
1999: SM Kang; Casey D Morrow
Genetic analysis of a unique human immunodeficiency virus type 1 (HIV-1) with a primer binding site complementary to tRNAMet supports a role for U5-PBS stem-loop RNA structures in initiation of HIV-1 reverse transcription.
Journal of virology 1999;73(3):1818-27.
1999: Qin Yu; Casey D Morrow
Complementarity between 3' terminal nucleotides of tRNA and primer binding site is a major determinant for selection of the tRNA primer used for initiation of HIV-1 reverse transcription.
Virology 1999;254(1):160-8.
1999: Casey D Morrow; Miroslav J Novak; David C Ansardi; DC Porter; Zina Moldoveanu
Recombinant viruses as vectors for mucosal immunity.
Current topics in microbiology and immunology 1999;236():255-73.
1998: Z Zhang; SM Kang; Casey D Morrow
Genetic evidence of the interaction between tRNA(Lys,3) and U5 facilitating efficient initiation of reverse transcription by human immunodeficiency virus type 1.
AIDS research and human retroviruses 1998;14(11):979-88.
1998: Z Zhang; Qin Yu; SM Kang; J Buescher; Casey D Morrow
Preferential completion of human immunodeficiency virus type 1 proviruses initiated with tRNA3Lys rather than tRNA1,2Lys.
Journal of virology 1998;72(7):5464-71.
1998: S Basak; Sylvia A McPherson; S Kang; James F Collawn; Casey D Morrow
Construction and characterization of encapsidated poliovirus replicons that express biologically active murine interleukin-2.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1998;18(5):305-13.
1998: Z Zhang; SM Kang; Yingying Li; Casey D Morrow
Genetic analysis of the U5-PBS of a novel HIV-1 reveals multiple interactions between the tRNA and RNA genome required for initiation of reverse transcription.
RNA (New York, N.Y.) 1998;4(4):394-406.
1998: DC Porter; David C Ansardi; J Wang; Sylvia A McPherson; Zina Moldoveanu; Casey D Morrow
Demonstration of the specificity of poliovirus encapsidation using a novel replicon which encodes enzymatically active firefly luciferase.
Virology 1998;243(1):1-11.
1997: Yingying Li; Z Zhang; SM Kang; J L Buescher; Casey D Morrow
Insights into the interaction between tRNA and primer binding site from characterization of a unique HIV-1 virus which stably maintains dual PBS complementary to tRNA(Gly) and tRNA(His).
Virology 1997;238(2):273-82.
1997: Yingying Li; Z Zhang; John K Wakefield; SM Kang; Casey D Morrow
Nucleotide substitutions within U5 are critical for efficient reverse transcription of human immunodeficiency virus type 1 with a primer binding site complementary to tRNA(His).
Journal of virology 1997;71(9):6315-22.
1997: Yingying Li; SM Kang; Casey D Morrow
Stability of HIV type 1 proviral genomes that contain two distinct primer-binding sites.
AIDS research and human retroviruses 1997;13(3):253-62.
1997: DC Porter; J Wang; Zina Moldoveanu; Sylvia A McPherson; Casey D Morrow
Immunization of mice with poliovirus replicons expressing the C-fragment of tetanus toxin protects against lethal challenge with tetanus toxin.
Vaccine 1997;15(3):257-64.
1997: M J Anderson; DC Porter; Zina Moldoveanu; Thomas M Fletcher; Sylvia A McPherson; Casey D Morrow
Characterization of the expression and immunogenicity of poliovirus replicons that encode simian immunodeficiency virus SIVmac239 Gag or envelope SU proteins.
AIDS research and human retroviruses 1997;13(1):53-62.
1997: SM Kang; Z Zhang; Casey D Morrow
Identification of a sequence within U5 required for human immunodeficiency virus type 1 to stably maintain a primer binding site complementary to tRNA(Met).
Journal of virology 1997;71(1):207-17.
1996: Z Zhang; SM Kang; A LeBlanc; Stephen L Hajduk; Casey D Morrow
Nucleotide sequences within the U5 region of the viral RNA genome are the major determinants for an human immunodeficiency virus type 1 to maintain a primer binding site complementary to tRNA(His).
Virology 1996;226(2):306-17.
1996: SM Kang; J K Wakefield; Casey D Morrow
Mutations in both the U5 region and the primer-binding site influence the selection of the tRNA used for the initiation of HIV-1 reverse transcription.
Virology 1996;222(2):401-14.
1996: J K Wakefield; Casey D Morrow
Mutations within the primer binding site of the human immunodeficiency virus type 1 define sequence requirements essential for reverse transcription.
Virology 1996;220(2):290-8.
1996: J E Wilson; A Aulabaugh; B Caligan; Sylvia A McPherson; J K Wakefield; S Jablonski; Casey D Morrow; J E Reardon; P A Furman
Human immunodeficiency virus type-1 reverse transcriptase. Contribution of Met-184 to binding of nucleoside 5'-triphosphate.
The Journal of biological chemistry 1996;271(23):13656-62.
1996: M J Anderson; DC Porter; P N Fultz; Casey D Morrow
Poliovirus replicons that express the gag or the envelope surface protein of simian immunodeficiency virus SIV(smm) PBj14.
Virology 1996;219(1):140-9.
1996: DC Porter; L R Melsen; Richard W Compans; Casey D Morrow
Release of virus-like particles from cells infected with poliovirus replicons which express human immunodeficiency virus type 1 Gag.
Journal of virology 1996;70(4):2643-9.
1996: J K Wakefield; SM Kang; Casey D Morrow
Construction of a type 1 human immunodeficiency virus that maintains a primer binding site complementary to tRNA(His).
Journal of virology 1996;70(2):966-75.
1996: David C Ansardi; DC Porter; M J Anderson; Casey D Morrow
Poliovirus assembly and encapsidation of genomic RNA.
Advances in virus research 1996;46():1-68.
1995: D E Walker; D McPherson; S A Jablonski; Sylvia A McPherson; Casey D Morrow
An aspartic acid at amino acid 108 is required to rescue infectious virus after transfection of a poliovirus cDNA containing a CGDD but not SGDD amino acid motif in 3Dpol.
Journal of virology 1995;69(12):8173-7.
1995: J K Wakefield; A G Wolf; Casey D Morrow
Human immunodeficiency virus type 1 can use different tRNAs as primers for reverse transcription but selectively maintains a primer binding site complementary to tRNA(3Lys).
Journal of virology 1995;69(10):6021-9.
1995: Zina Moldoveanu; DC Porter; A Lu; Sylvia A McPherson; Casey D Morrow
Immune responses induced by administration of encapsidated poliovirus replicons which express HIV-1 gag and envelope proteins.
Vaccine 1995;13(11):1013-22.
1995: DC Porter; David C Ansardi; Casey D Morrow
Encapsidation of poliovirus replicons encoding the complete human immunodeficiency virus type 1 gag gene by using a complementation system which provides the P1 capsid protein in trans.
Journal of virology 1995;69(3):1548-55.
1995: David C Ansardi; Casey D Morrow
Amino acid substitutions in the poliovirus maturation cleavage site affect assembly and result in accumulation of provirions.
Journal of virology 1995;69(3):1540-7.
1995: S A Jablonski; Casey D Morrow
Mutation of the aspartic acid residues of the GDD sequence motif of poliovirus RNA-dependent RNA polymerase results in enzymes with altered metal ion requirements for activity.
Journal of virology 1995;69(3):1532-9.
1995: David C Ansardi; R Pal-Ghosh; D Porter; Casey D Morrow
Encapsidation and serial passage of a poliovirus replicon which expresses an inactive 2A proteinase.
Journal of virology 1995;69(2):1359-66.
1994: David C Ansardi; Zina Moldoveanu; DC Porter; D E Walker; Robert M Conry; Albert F LoBuglio; Sylvia A McPherson; Casey D Morrow
Characterization of poliovirus replicons encoding carcinoembryonic antigen.
Cancer research 1994;54(24):6359-64.
1994: Abdesslem Faraj; L A Agrofoglio; J K Wakefield; Sylvia A McPherson; Casey D Morrow; Gilles Gosselin; C Mathe; Jean-Louis Imbach; Ray F Schinazi; Jean-Pierre Sommadossi
Inhibition of human immunodeficiency virus type 1 reverse transcriptase by the 5'-triphosphate beta enantiomers of cytidine analogs.
Antimicrobial agents and chemotherapy 1994;38(10):2300-5.
1994: Casey D Morrow; J Park; J K Wakefield
Viral gene products and replication of the human immunodeficiency type 1 virus.
The American journal of physiology 1994;266(5 Pt 1):C1135-56.
1994: J K Wakefield; H Rhim; Casey D Morrow
Minimal sequence requirements of a functional human immunodeficiency virus type 1 primer binding site.
Journal of virology 1994;68(3):1605-14.
1994: David C Ansardi; Ming Luo; Casey D Morrow
Mutations in the poliovirus P1 capsid precursor at arginine residues VP4-ARG34, VP3-ARG223, and VP1-ARG129 affect virus assembly and encapsidation of genomic RNA.
Virology 1994;199(1):20-34.
1994: Casey D Morrow; DC Porter; David C Ansardi; Zina Moldoveanu; P N Fultz
New approaches for mucosal vaccines for AIDS: encapsidation and serial passages of poliovirus replicons that express HIV-1 proteins on infection.
AIDS research and human retroviruses 1994;10 Suppl 2():S61-6.
1993: David C Ansardi; Casey D Morrow
Poliovirus capsid proteins derived from P1 precursors with glutamine-valine cleavage sites have defects in assembly and RNA encapsidation.
Journal of virology 1993;67(12):7284-97.
1993: DC Porter; David C Ansardi; Michael R Lentz; Casey D Morrow
Expression of poliovirus P3 proteins using a recombinant vaccinia virus results in proteolytically active 3CD precursor protein without further processing to 3Cpro and 3Dpol.
Virus research 1993;29(3):241-54.
1993: R Pal-Ghosh; Casey D Morrow
A poliovirus minireplicon containing an inactive 2A proteinase is expressed in vaccinia virus-infected cells.
Journal of virology 1993;67(8):4621-9.
1993: DC Porter; David C Ansardi; W S Choi; Casey D Morrow
Encapsidation of genetically engineered poliovirus minireplicons which express human immunodeficiency virus type 1 Gag and Pol proteins upon infection.
Journal of virology 1993;67(7):3712-9.
1993: J Park; Casey D Morrow
Mutations in the protease gene of human immunodeficiency virus type 1 affect release and stability of virus particles.
Virology 1993;194(2):843-50.
1993: David C Ansardi; DC Porter; Casey D Morrow
Complementation of a poliovirus defective genome by a recombinant vaccinia virus which provides poliovirus P1 capsid precursor in trans.
Journal of virology 1993;67(6):3684-90.
1993: S A Jablonski; Casey D Morrow
Enzymatic activity of poliovirus RNA polymerases with mutations at the tyrosine residue of the conserved YGDD motif: isolation and characterization of polioviruses containing RNA polymerases with FGDD and MGDD sequences.
Journal of virology 1993;67(1):373-81.
1992: J K Wakefield; S A Jablonski; Casey D Morrow
In vitro enzymatic activity of human immunodeficiency virus type 1 reverse transcriptase mutants in the highly conserved YMDD amino acid motif correlates with the infectious potential of the proviral genome.
Journal of virology 1992;66(11):6806-12.
1992: J Park; Casey D Morrow
The nonmyristylated Pr160gag-pol polyprotein of human immunodeficiency virus type 1 interacts with Pr55gag and is incorporated into viruslike particles.
Journal of virology 1992;66(11):6304-13.
1992: David C Ansardi; DC Porter; Casey D Morrow
Myristylation of poliovirus capsid precursor P1 is required for assembly of subviral particles.
Journal of virology 1992;66(7):4556-63.
1991: J Park; Casey D Morrow
Overexpression of the gag-pol precursor from human immunodeficiency virus type 1 proviral genomes results in efficient proteolytic processing in the absence of virion production.
Journal of virology 1991;65(9):5111-7.
1991: H Rhim; J Park; Casey D Morrow
Deletions in the tRNA(Lys) primer-binding site of human immunodeficiency virus type 1 identify essential regions for reverse transcription.
Journal of virology 1991;65(9):4555-64.
1991: S A Jablonski; Ming Luo; Casey D Morrow
Enzymatic activity of poliovirus RNA polymerase mutants with single amino acid changes in the conserved YGDD amino acid motif.
Journal of virology 1991;65(9):4565-72.
1991: W S Choi; R Pal-Ghosh; Casey D Morrow
Expression of human immunodeficiency virus type 1 (HIV-1) gag, pol, and env proteins from chimeric HIV-1-poliovirus minireplicons.
Journal of virology 1991;65(6):2875-83.
1991: David C Ansardi; DC Porter; Casey D Morrow
Coinfection with recombinant vaccinia viruses expressing poliovirus P1 and P3 proteins results in polyprotein processing and formation of empty capsid structures.
Journal of virology 1991;65(4):2088-92.
1987: Casey D Morrow; B Warren; Michael R Lentz
Expression of enzymatically active poliovirus RNA-dependent RNA polymerase in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(17):6050-4.