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Joachim Morschhäuser

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Candidiasis

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Florian Hennicke; Christian Hertweck; Bernhard Hube; Ilse D Jacobsen; Ulrich Lermann; Michel Monod; Joachim Morschhäuser; Katja Palige; Claudia Staib; Bettina Böttcher; Maria Grumbt; Nico Ueberschaar; Peter Staib
Factors supporting cysteine tolerance and sulfite production in Candida albicans.
Nico Dunkel; Renate Franz; Tobias Hertlein; Knut Ohlsen; Oliver Reuß; Christoph Sasse; Tina Schäfer; Joachim Morschhäuser
Roles of different peptide transporters in nutrient acquisition in Candida albicans.
Katja Palige; Steffen Rupp; Claudia Staib; Bettina Böttcher; Francesco Citiulo; Bernhard Hube; Jörg Linde; Ronny Martin; Joachim Morschhäuser; Derek J Sullivan; Johann Weber; Peter Staib
Global Transcriptome Sequencing Identifies Chlamydospore Specific Markers in Candida albicans and Candida dubliniensis.

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All Publications

2013: Florian Hennicke; Christian Hertweck; Bernhard Hube; Ilse D Jacobsen; Ulrich Lermann; Michel Monod; Joachim Morschhäuser; Katja Palige; Claudia Staib; Bettina Böttcher; Maria Grumbt; Nico Ueberschaar; Peter Staib
Factors supporting cysteine tolerance and sulfite production in Candida albicans.
Eukaryotic cell 2013;12(4):604-13.
2013: Nico Dunkel; Renate Franz; Tobias Hertlein; Knut Ohlsen; Oliver Reuß; Christoph Sasse; Tina Schäfer; Joachim Morschhäuser
Roles of different peptide transporters in nutrient acquisition in Candida albicans.
Eukaryotic cell 2013;12(4):520-8.
2013: Katja Palige; Steffen Rupp; Claudia Staib; Bettina Böttcher; Francesco Citiulo; Bernhard Hube; Jörg Linde; Ronny Martin; Joachim Morschhäuser; Derek J Sullivan; Johann Weber; Peter Staib
Global Transcriptome Sequencing Identifies Chlamydospore Specific Markers in Candida albicans and Candida dubliniensis.
PloS one 2013;8(4):e61940.
2013: Christoph Sasse; Michael Weyler; Matthias Gunzer; Mike Hasenberg; Joachim Morschhäuser
White-opaque switching of Candida albicans allows immune evasion in an environment-dependent fashion.
Eukaryotic cell 2013;12(1):50-8.
2012: Christoph Sasse; Tina Schäfer; Sabrina Schneider; Franziska Dierolf; Nico Dunkel; Knut Ohlsen; Joachim Morschhäuser
The stepwise acquisition of fluconazole resistance mutations causes a gradual loss of fitness in Candida albicans.
Molecular microbiology 2012;86(3):539-56.
2012: Stephanie A Flowers; Scott E Gygax; Joachim Morschhäuser; Katherine S Barker; Elizabeth L Berkow; Sean G Chadwick; Geoffrey Toner; P David Rogers
Gain-of-function mutations in UPC2 are a frequent cause of ERG11 upregulation in azole-resistant clinical isolates of Candida albicans.
Eukaryotic cell 2012;11(10):1289-99.
2012: Christoph Sasse; Rebecca Schillig; Julia Merk; Alexandra Reimund; Joachim Morschhäuser
Inducible and constitutive activation of two polymorphic promoter alleles of the Candida albicans multidrug efflux pump MDR1.
Antimicrobial agents and chemotherapy 2012;56(8):4490-4.
2012: Michael Weyler; Joachim Morschhäuser
Tetracycline-inducible gene expression in Candida albicans.
Methods in molecular biology (Clifton, N.J.) 2012;845():201-10.
2012: Christoph Sasse; Joachim Morschhäuser
Gene deletion in Candida albicans wild-type strains using the SAT1-flipping strategy.
Methods in molecular biology (Clifton, N.J.) 2012;845():3-17.
2011: Prashant Ramesh Desai; Dwaipayan Ganguli; Joachim Morschhäuser; Sanjoy Paul; Anil Thakur; Anand K Bachhawat
Glutathione utilization by Candida albicans requires a functional glutathione degradation (DUG) pathway and OPT7, an unusual member of the oligopeptide transporter family.
The Journal of biological chemistry 2011;286(48):41183-94.
2011: Thomas Hartmann; Elaine Bignell; Timothy C Cairns; Joachim Morschhäuser; Patrick Olbermann; Sven Krappmann
Oligopeptide transport and regulation of extracellular proteolysis are required for growth of Aspergillus fumigatus on complex substrates but not for virulence.
Molecular microbiology 2011;82(4):917-35.
2011: Sabrina Schubert; Christina Popp; P David Rogers; Joachim Morschhäuser
Functional dissection of a Candida albicans zinc cluster transcription factor, the multidrug resistance regulator Mrr1.
Eukaryotic cell 2011;10(8):1110-21.
2011: Axel A Brakhage; Uwe Gross; Joachim Morschhäuser
Pathobiology of human-pathogenic fungi.
International journal of medical microbiology : IJMM 2011;301(5):367.
2011: Joachim Morschhäuser
Nitrogen regulation of morphogenesis and protease secretion in Candida albicans.
International journal of medical microbiology : IJMM 2011;301(5):390-4.
2011: Sabrina Schubert; Katherine S Barker; Sadri Znaidi; Sabrina Schneider; Franziska Dierolf; Nico Dunkel; Malika Aïd; Geneviève Boucher; P David Rogers; Martine Raymond; Joachim Morschhäuser
Regulation of efflux pump expression and drug resistance by the transcription factors Mrr1, Upc2, and Cap1 in Candida albicans.
Antimicrobial agents and chemotherapy 2011;55(5):2212-23.
2011: Claudia Rennemeier; Michael Schwab; Ulrich Lermann; Christa Albert; Ulrike Kämmerer; Torsten Frambach; Joachim Morschhäuser; Johannes Dietl; Peter Staib
Seminal plasma protects human spermatozoa and pathogenic yeasts from capture by dendritic cells.
Human reproduction (Oxford, England) 2011;26(5):987-99.
2011: Selene Mogavero; Arianna Tavanti; Sonia Senesi; P David Rogers; Joachim Morschhäuser
Differential requirement of the transcription factor Mcm1 for activation of the Candida albicans multidrug efflux pump MDR1 by its regulators Mrr1 and Cap1.
Antimicrobial agents and chemotherapy 2011;55(5):2061-6.
2011: Benjamin Neuhäuser; Nico Dunkel; Somisetty V Satheesh; Joachim Morschhäuser
Role of the Npr1 kinase in ammonium transport and signaling by the ammonium permease Mep2 in Candida albicans.
Eukaryotic cell 2011;10(3):332-42.
2011: Christian Büchold; Yasmin Hemberger; Cornelia Heindl; Armin Welker; Björn Degel; Thomas Pfeuffer; Peter Staib; Sabrina Schneider; Philip J Rosenthal; Jiri Gut; Joachim Morschhäuser; Gerhard Bringmann; Tanja Schirmeister
New cis-configured aziridine-2-carboxylates as aspartic acid protease inhibitors.
ChemMedChem 2011;6(1):141-52.
2011: Christoph Sasse; Rebecca Schillig; Sabrina Schneider; Michael Weyler; Franziska Dierolf; Selene Mogavero; P David Rogers; Joachim Morschhäuser
The transcription factor Ndt80 does not contribute to Mrr1-, Tac1-, and Upc2-mediated fluconazole resistance in Candida albicans.
PloS one 2011;6(9):e25623.
2011: Nico Dunkel; Joachim Morschhäuser
Loss of heterozygosity at an unlinked genomic locus is responsible for the phenotype of a Candida albicans sap4Δ sap5Δ sap6Δ mutant.
Eukaryotic cell 2011;10(1):54-62.
2011: Dhammika H M L P Navarathna; Aditi Das; Joachim Morschhäuser; Kenneth W Nickerson; David D Roberts
Dur3 is the major urea transporter in Candida albicans and is co-regulated with the urea amidolyase Dur1,2.
Microbiology (Reading, England) 2011;157(Pt 1):270-9.
2010: Krzysztof Kur; Iwona Gabriel; Joachim Morschhäuser; Francesco Barchiesi; Elisabetta Spreghini; Slawomir Milewski
Disruption of homocitrate synthase genes in Candida albicans affects growth but not virulence.
Mycopathologia 2010;170(6):397-402.
2010: Alexandra Correia; Ulrich Lermann; Luzia Teixeira; Filipe Cerca; Sofia Botelho; Rui M Gil da Costa; Paula Sampaio; Fátima Gärtner; Joachim Morschhäuser; Manuel Vilanova; Célia Pais
Limited role of secreted aspartyl proteinases Sap1 to Sap6 in Candida albicans virulence and host immune response in murine hematogenously disseminated candidiasis.
Infection and immunity 2010;78(11):4839-49.
2010: Thomas Hartmann; Michaela Dümig; Basem M Jaber; Edyta Szewczyk; Patrick Olbermann; Joachim Morschhäuser; Sven Krappmann
Validation of a self-excising marker in the human pathogen Aspergillus fumigatus by employing the beta-rec/six site-specific recombination system.
Applied and environmental microbiology 2010;76(18):6313-7.
2010: Guotao Fan; Zelin Li; Shi Shen; Yi Zeng; Yishu Yang; Minjuang Xu; Torsten Bruhn; Heike Bruhn; Joachim Morschhäuser; Gerhard Bringmann; Wenhan Lin
Baculiferins A-O, O-sulfated pyrrole alkaloids with anti-HIV-1 activity, from the Chinese marine sponge Iotrochota baculifera.
Bioorganic & medicinal chemistry 2010;18(15):5466-74.
2010: Joachim Morschhäuser
Regulation of white-opaque switching in Candida albicans.
Medical microbiology and immunology 2010;199(3):165-72.
2010: Joachim Morschhäuser
Regulation of multidrug resistance in pathogenic fungi.
Fungal genetics and biology : FG & B 2010;47(2):94-106.
2010: Clemens J. Heilmann; Sabrina Schneider; Katherine S Barker; P David Rogers; Joachim Morschhäuser
An A643T mutation in the transcription factor Upc2p causes constitutive ERG11 upregulation and increased fluconazole resistance in Candida albicans.
Antimicrobial agents and chemotherapy 2010;54(1):353-9.
2009: Christopher F Hoehamer; Edwin D Cummings; George M Hilliard; Joachim Morschhäuser; Phillip David Rogers
Upc2p-associated differential protein expression in Candida albicans.
Proteomics 2009;9(20):4726-30.
2009: Christopher F Hoehamer; Edwin D Cummings; George M Hilliard; Joachim Morschhäuser; P David Rogers
Proteomic analysis of Mrr1p- and Tac1p-associated differential protein expression in azole-resistant clinical isolates of Candida albicans.
Proteomics. Clinical applications 2009;3(8):968-78.
2009: Florian Diwischek; Joachim Morschhäuser; Ulrike Holzgrabe
Cerulenin analogues as inhibitors of efflux pumps in drug-resistant Candida albicans.
Archiv der Pharmazie 2009;342(3):150-64.
2009: Neelam Dabas; Sabrina Schneider; Joachim Morschhäuser
Mutational analysis of the Candida albicans ammonium permease Mep2p reveals residues required for ammonium transport and signaling.
Eukaryotic cell 2009;8(2):147-60.
2008: Sabrina Schubert; P David Rogers; Joachim Morschhäuser
Gain-of-function mutations in the transcription factor MRR1 are responsible for overexpression of the MDR1 efflux pump in fluconazole-resistant Candida dubliniensis strains.
Antimicrobial agents and chemotherapy 2008;52(12):4274-80.
2008: Ulrich Lermann; Joachim Morschhäuser
Secreted aspartic proteases are not required for invasion of reconstituted human epithelia by Candida albicans.
Microbiology (Reading, England) 2008;154(Pt 11):3281-95.
2008: Nico Dunkel; Julia Blass; P David Rogers; Joachim Morschhäuser
Mutations in the multi-drug resistance regulator MRR1, followed by loss of heterozygosity, are the main cause of MDR1 overexpression in fluconazole-resistant Candida albicans strains.
Molecular microbiology 2008;69(4):827-40.
2008: Neelam Dabas; Joachim Morschhäuser
A transcription factor regulatory cascade controls secreted aspartic protease expression in Candida albicans.
Molecular microbiology 2008;69(3):586-602.
2008: Nico Dunkel; Teresa T Liu; Katherine S Barker; Ramin Homayouni; Joachim Morschhäuser; P David Rogers
A gain-of-function mutation in the transcription factor Upc2p causes upregulation of ergosterol biosynthesis genes and increased fluconazole resistance in a clinical Candida albicans isolate.
Eukaryotic cell 2008;7(7):1180-90.
2008: Bernardo Ramírez-Zavala; Oliver Reuss; Yang-Nim Park; Knut Ohlsen; Joachim Morschhäuser
Environmental induction of white-opaque switching in Candida albicans.
PLoS pathogens 2008;4(6):e1000089.
2008: Raman Manoharlal; Naseem Akhtar Gaur; Sneh Lata Panwar; Joachim Morschhäuser; Rajendra Prasad
Transcriptional activation and increased mRNA stability contribute to overexpression of CDR1 in azole-resistant Candida albicans.
Antimicrobial agents and chemotherapy 2008;52(4):1481-92.
2008: Harald Kusch; Susanne Engelmann; Rüdiger Bode; Dirk Albrecht; Joachim Morschhäuser; Michael Hecker
A proteomic view of Candida albicans yeast cell metabolism in exponential and stationary growth phases.
International journal of medical microbiology : IJMM 2008;298(3-4):291-318.
2008: Björn Degel; Peter Staib; Sebastian Rohrer; Josef Scheiber; Erika Martina; Christian Büchold; Knut Baumann; Joachim Morschhäuser; Tanja Schirmeister
Cis-Configured aziridines are new pseudo-irreversible dual-mode inhibitors of Candida albicans secreted aspartic protease 2.
ChemMedChem 2008;3(2):302-15.
2008: Peter Staib; Ulrich Lermann; Julia Blass-Warmuth; Björn Degel; Reinhard Wurzner; Michel Monod; Tanja Schirmeister; Joachim Morschhäuser
Tetracycline-inducible expression of individual secreted aspartic proteases in Candida albicans allows isoenzyme-specific inhibitor screening.
Antimicrobial agents and chemotherapy 2008;52(1):146-56.
2007: Joachim Morschhäuser; Katherine S Barker; Teresa T Liu; Julia BlaB-Warmuth; Ramin Homayouni; P David Rogers
The transcription factor Mrr1p controls expression of the MDR1 efflux pump and mediates multidrug resistance in Candida albicans.
PLoS pathogens 2007;3(11):e164.
2007: Teresa T Liu; Sadri Znaidi; Katherine S Barker; Lijing Xu; Ramin Homayouni; Saloua Saidane; Joachim Morschhäuser; André Nantel; Martine Raymond; P David Rogers
Genome-wide expression and location analyses of the Candida albicans Tac1p regulon.
Eukaryotic cell 2007;6(11):2122-38.
2007: Neelam Dabas; Joachim Morschhäuser
Control of ammonium permease expression and filamentous growth by the GATA transcription factors GLN3 and GAT1 in Candida albicans.
Eukaryotic cell 2007;6(5):875-88.
2007: Roland Wakieć; Rajendra Prasad; Joachim Morschhäuser; Francesco Barchiesi; Edward Borowski; Slawomir Milewski
Voriconazole and multidrug resistance in Candida albicans.
Mycoses 2007;50(2):109-15.
2007: Harald Kusch; Susanne Engelmann; Dirk Albrecht; Joachim Morschhäuser; Michael Hecker
Proteomic analysis of the oxidative stress response in Candida albicans.
Proteomics 2007;7(5):686-97.
2007: Peter Staib; Joachim Morschhäuser
Chlamydospore formation in Candida albicans and Candida dubliniensis--an enigmatic developmental programme.
Mycoses 2007;50(1):1-12.
2006: Davina Hiller; Stephanie Stahl; Joachim Morschhäuser
Multiple cis-acting sequences mediate upregulation of the MDR1 efflux pump in a fluconazole-resistant clinical Candida albicans isolate.
Antimicrobial agents and chemotherapy 2006;50(7):2300-8.
2006: Teresa Bader; Klaus Schröppel; Stefan Bentink; Nina Agabian; Gerwald A Köhler; Joachim Morschhäuser
Role of calcineurin in stress resistance, morphogenesis, and virulence of a Candida albicans wild-type strain.
Infection and immunity 2006;74(7):4366-9.
2006: Oliver Reuss; Joachim Morschhäuser
A family of oligopeptide transporters is required for growth of Candida albicans on proteins.
Molecular microbiology 2006;60(3):795-812.
2006: Davina Hiller; Dominique Sanglard; Joachim Morschhäuser
Overexpression of the MDR1 gene is sufficient to confer increased resistance to toxic compounds in Candida albicans.
Antimicrobial agents and chemotherapy 2006;50(4):1365-71.
2006: Alix T Coste; Vincent Turner; Françoise Ischer; Joachim Morschhäuser; Anja Forche; Anna Selmecki; Judith Berman; Jacques Bille; Dominique Sanglard
A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans.
Genetics 2006;172(4):2139-56.
2005: Yang-Nim Park; Joachim Morschhäuser
Candida albicans MTLalpha tup1Delta mutants can reversibly switch to mating-competent, filamentous growth forms.
Molecular microbiology 2005;58(5):1288-302.
2005: Yang-Nim Park; Joachim Morschhäuser
Tetracycline-inducible gene expression and gene deletion in Candida albicans.
Eukaryotic cell 2005;4(8):1328-42.
2005: Naseem Akhtar Gaur; Raman Manoharlal; Preeti Saini; Tulika Prasad; Gauranga Mukhopadhyay; Milan Hoefer; Joachim Morschhäuser; Rajendra Prasad
Expression of the CDR1 efflux pump in clinical Candida albicans isolates is controlled by a negative regulatory element.
Biochemical and biophysical research communications 2005;332(1):206-14.
2005: Kajal Biswas; Joachim Morschhäuser
The Mep2p ammonium permease controls nitrogen starvation-induced filamentous growth in Candida albicans.
Molecular microbiology 2005;56(3):649-69.
2005: Brad N Taylor; Peter Staib; Ayfer Binder; Antje Biesemeier; Miriam Sehnal; Martin Röllinghoff; Joachim Morschhäuser; Klaus Schröppel
Profile of Candida albicans-secreted aspartic proteinase elicited during vaginal infection.
Infection and immunity 2005;73(3):1828-35.
2005: Joachim Morschhäuser; Peter Staib; Gerwald A Köhler
Targeted gene deletion in Candida albicans wild-type strains by MPAR flipping.
Methods in molecular medicine 2005;118():35-44.
2005: Joachim Morschhäuser; Peter Staib; Gerwald A Köhler
CARE-2 fingerprinting of Candida albicans isolates.
Methods in molecular medicine 2005;118():27-34.
2005: Peter Staib; Joachim Morschhäuser
Liquid growth conditions for abundant chlamydospore formation in Candida dubliniensis.
Mycoses 2005;48(1):50-4.
2005: Peter Staib; Joachim Morschhäuser
Differential expression of the NRG1 repressor controls species-specific regulation of chlamydospore development in Candida albicans and Candida dubliniensis.
Molecular microbiology 2005;55(2):637-52.
2004: Oliver Reuss; Ashild Vik; Roberto Kolter; Joachim Morschhäuser
The SAT1 flipper, an optimized tool for gene disruption in Candida albicans.
Gene 2004;341():119-27.
2004: Yang-Nim Park; A Strauss; Joachim Morschhäuser
The white-phase-specific gene WH11 is not required for white-opaque switching in Candida albicans.
Molecular genetics and genomics : MGG 2004;272(1):88-97.
2004: Massoumeh Z Hooshdaran; Katherine S Barker; George M Hilliard; Harald Kusch; Joachim Morschhäuser; P David Rogers
Proteomic analysis of azole resistance in Candida albicans clinical isolates.
Antimicrobial agents and chemotherapy 2004;48(7):2733-5.
2004: Harald Kusch; K Biswas; S Schwanfelder; Susanne Engelmann; P David Rogers; Michael Hecker; Joachim Morschhäuser
A proteomic approach to understanding the development of multidrug-resistant Candida albicans strains.
Molecular genetics and genomics : MGG 2004;271(5):554-65.
2004: Peter Staib; Ayfer Binder; Marianne Kretschmar; Thomas Nichterlein; Klaus Schröppel; Joachim Morschhäuser
Tec1p-independent activation of a hypha-associated Candida albicans virulence gene during infection.
Infection and immunity 2004;72(4):2386-9.
2003: Kajal Biswas; Klaus-Jörg Rieger; Joachim Morschhäuser
Functional characterization of CaCBF1, the Candida albicans homolog of centromere binding factor 1.
Gene 2003;323():43-55.
2003: Teresa Bader; Barbara Bodendorfer; Klaus Schröppel; Joachim Morschhäuser
Calcineurin is essential for virulence in Candida albicans.
Infection and immunity 2003;71(9):5344-54.
2003: Claudia Montagnoli; Silvia Bozza; Angela Bacci; Roberta Gaziano; Paolo Mosci; Joachim Morschhäuser; Lucia Pitzurra; Manfred Kopf; Jim Cutler; Luigina Romani
A role for antibodies in the generation of memory antifungal immunity.
European journal of immunology 2003;33(5):1193-204.
2003: Kajal Biswas; Klaus-Jörg Rieger; Joachim Morschhäuser
Functional analysis of CaRAP1, encoding the Repressor/activator protein 1 of Candida albicans.
Gene 2003;307():151-8.
2003: Joachim Morschhäuser
[How do fungal infections "escape" treatment? Resistance and resistance mechanisms].
Pharmazie in unserer Zeit 2003;32(2):124-8.
2003: Carlos Balsalobre; Joachim Morschhäuser; Jana Jass; Jörg Hacker; Bernt Eric Uhlin
Transcriptional analysis of the sfa determinant revealing mmRNA processing events in the biogenesis of S fimbriae in pathogenic Escherichia coli.
Journal of bacteriology 2003;185(2):620-9.
2002: Sonja Michel; Sophia C Ushinsky; Bert Klebl; Ekkehard Leberer; David Thomas; Malcolm Whiteway; Joachim Morschhäuser
Generation of conditional lethal Candida albicans mutants by inducible deletion of essential genes.
Molecular microbiology 2002;46(1):269-80.
2002: Gary Moran; Derek Sullivan; Joachim Morschhäuser; David Coleman
The Candida dubliniensis CdCDR1 gene is not essential for fluconazole resistance.
Antimicrobial agents and chemotherapy 2002;46(9):2829-41.
2002: Joachim Morschhäuser
The genetic basis of fluconazole resistance development in Candida albicans.
Biochimica et biophysica acta 2002;1587(2-3):240-8.
2002: Peter Staib; Marianne Kretschmar; Thomas Nichterlein; Holger Hof; Joachim Morschhäuser
Host versus in vitro signals and intrastrain allelic differences in the expression of a Candida albicans virulence gene.
Molecular microbiology 2002;44(5):1351-66.
2002: Marianne Kretschmar; Angelika Felk; Peter Staib; Martin Schaller; Daniela Hess; Melvin Callapina; Joachim Morschhäuser; Wilhelm Schäfer; Hans Christian Korting; Holger Hof; Bernhard Hube; Thomas Nichterlein
Individual acid aspartic proteinases (Saps) 1-6 of Candida albicans are not essential for invasion and colonization of the gastrointestinal tract in mice.
Microbial pathogenesis 2002;32(2):61-70.
2002: Peter Staib; Marianne Kretschmar; Thomas Nichterlein; Holger Hof; Joachim Morschhäuser
Transcriptional regulators Cph1p and Efg1p mediate activation of the Candida albicans virulence gene SAP5 during infection.
Infection and immunity 2002;70(2):921-7.
2001: S Wirsching; Gary P Moran; Derek Sullivan; David C Coleman; Joachim Morschhäuser
MDR1-mediated drug resistance in Candida dubliniensis.
Antimicrobial agents and chemotherapy 2001;45(12):3416-21.
2001: A Strauss; Sonja Michel; Joachim Morschhäuser
Analysis of phase-specific gene expression at the single-cell level in the white-opaque switching system of Candida albicans.
Journal of bacteriology 2001;183(12):3761-9.
2001: P Staib; S Wirsching; A Strauss; Joachim Morschhäuser
Gene regulation and host adaptation mechanisms in Candida albicans.
International journal of medical microbiology : IJMM 2001;291(2):183-8.
2001: Peter Staib; Gary P Moran; Derek Sullivan; David C Coleman; Joachim Morschhäuser
Isogenic strain construction and gene targeting in Candida dubliniensis.
Journal of bacteriology 2001;183(9):2859-65.
2000: Joachim Morschhäuser; G Köhler; Wilma Ziebuhr; Gabriele Blum-Oehler; Ulrich Dobrindt; Jörg Hacker
Evolution of microbial pathogens.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2000;355(1397):695-704.
2000: Peter Staib; Marianne Kretschmar; Thomas Nichterlein; Holger Hof; Joachim Morschhäuser
Differential activation of a Candida albicans virulence gene family during infection.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):6102-7.
2000: S Wirsching; Sonja Michel; Joachim Morschhäuser
Targeted gene disruption in Candida albicans wild-type strains: the role of the MDR1 gene in fluconazole resistance of clinical Candida albicans isolates.
Molecular microbiology 2000;36(4):856-65.
2000: Peter Staib; Sonja Michel; Gerwald A Köhler; Joachim Morschhäuser
A molecular genetic system for the pathogenic yeast Candida dubliniensis.
Gene 2000;242(1-2):393-8.
2000: Peter Staib; Marianne Kretschmar; Thomas Nichterlein; Gerwald A Köhler; Joachim Morschhäuser
Expression of virulence genes in Candida albicans.
Advances in experimental medicine and biology 2000;485():167-76.
2000: Carlos Balsalobre; Joachim Morschhäuser; Jörg Hacker; Bernt Eric Uhlin
Transcriptional analysis of the sfa and pap determinants of uropathogenic Escherichia coli strains.
Advances in experimental medicine and biology 2000;485():119-22.
2000: S Wirsching; Sonja Michel; Gerwald A Köhler; Joachim Morschhäuser
Activation of the multiple drug resistance gene MDR1 in fluconazole-resistant, clinical Candida albicans strains is caused by mutations in a trans-regulatory factor.
Journal of bacteriology 2000;182(2):400-4.
1999: Joachim Morschhäuser; Sonja Michel; Peter Staib
Sequential gene disruption in Candida albicans by FLP-mediated site-specific recombination.
Molecular microbiology 1999;32(3):547-56.
1999: Peter Staib; Marianne Kretschmar; Thomas Nichterlein; Gerwald A Köhler; Sonja Michel; Holger Hof; Jörg Hacker; Joachim Morschhäuser
Host-induced, stage-specific virulence gene activation in Candida albicans during infection.
Molecular microbiology 1999;32(3):533-46.
1999: Joachim Morschhäuser; M Ruhnke; S Michel; Jörg Hacker
Identification of CARE-2-negative Candida albicans isolates as Candida dubliniensis.
Mycoses 1999;42(1-2):29-32.
1999: Frank-Michael C Müller; Joachim Morschhäuser; Gerwald A Köhler; Tobias A Oelschlaeger; Wilma Ziebuhr; Jörg Hacker
[Adherence and invasion-two pathogenicity factors in bacterial and fungal pathogens].
Mycoses 1999;42 Suppl 1():39-42.
1999: Peter Staib; Joachim Morschhäuser
Chlamydospore formation on Staib agar as a species-specific characteristic of Candida dubliniensis.
Mycoses 1999;42(9-10):521-4.
1999: R Franz; M Ruhnke; Joachim Morschhäuser
Molecular aspects of fluconazole resistance development in Candida albicans.
Mycoses 1999;42(7-8):453-8.
1999: M Ruhnke; I Grosch-Wörner; A Lischewski; A Neubauer; A Steinmüller; M Trautmann; Joachim Morschhäuser
Genotypic relatedness of yeast isolates from women infected with human immunodeficiency virus and their children.
Mycoses 1999;42(5-6):385-94.
1998: R Franz; S L Kelly; David C Lamb; Diane E Kelly; M Ruhnke; Joachim Morschhäuser
Multiple molecular mechanisms contribute to a stepwise development of fluconazole resistance in clinical Candida albicans strains.
Antimicrobial agents and chemotherapy 1998;42(12):3065-72.
1998: R Franz; Sonja Michel; Joachim Morschhäuser
A fourth gene from the Candida albicans CDR family of ABC transporters.
Gene 1998;220(1-2):91-8.
1998: Joachim Morschhäuser; S Michel; Jörg Hacker
Expression of a chromosomally integrated, single-copy GFP gene in Candida albicans, and its use as a reporter of gene regulation.
Molecular & general genetics : MGG 1998;257(4):412-20.
1997: A Lischewski; Dag Harmsen; Jörg Hacker; Joachim Morschhäuser
Standardized molecular typing of Candida albicans strains.
Mycoses 1997;40(9-10):369-72.
1997: A Lischewski; Marianne Kretschmar; H Hof; R Amann; Jörg Hacker; Joachim Morschhäuser
Detection and identification of Candida species in experimentally infected tissue and human blood by rRNA-specific fluorescent in situ hybridization.
Journal of clinical microbiology 1997;35(11):2943-8.
1997: Joachim Morschhäuser; Ritva Virkola; Timo K Korhonen; Jörg Hacker
Degradation of human subendothelial extracellular matrix by proteinase-secreting Candida albicans.
FEMS microbiology letters 1997;153(2):349-55.
1996: A Lischewski; R I Amann; Dag Harmsen; H Merkert; Jörg Hacker; Joachim Morschhäuser
Specific detection of Candida albicans and Candida tropicalis by fluorescent in situ hybridization with an 18S rRNA-targeted oligonucleotide probe.
Microbiology (Reading, England) 1996;142 ( Pt 10)():2731-40.
1996: T A Oelschlaeger; Joachim Morschhäuser; C Meier; C Schipper; Jörg Hacker
Adhesion and invasion of Escherichia coli. Studies on function and regulation.
Advances in experimental medicine and biology 1996;408():57-62.
1996: Joachim Morschhäuser; Gerwald A Köhler; Jörg Hacker
[Are there pathogenicity factors in fungi?].
Mycoses 1996;39 Suppl 1():51-4.
1995: A Lischewski; M Ruhnke; I Tennagen; G Schönian; Joachim Morschhäuser; Jörg Hacker
Molecular epidemiology of Candida isolates from AIDS patients showing different fluconazole resistance profiles.
Journal of clinical microbiology 1995;33(3):769-71.
1990: T Schmoll; Joachim Morschhäuser; M Ott; B Ludwig; I van Die; Jörg Hacker
Complete genetic organization and functional aspects of the Escherichia coli S fimbrial adhesion determinant: nucleotide sequence of the genes sfa B, C, D, E, F.
Microbial pathogenesis 1990;9(5):331-43.
1990: Joachim Morschhäuser; H Hoschützky; K Jann; Jörg Hacker
Functional analysis of the sialic acid-binding adhesin SfaS of pathogenic Escherichia coli by site-specific mutagenesis.
Infection and immunity 1990;58(7):2133-8.
1989: T Schmoll; H Hoschützky; Joachim Morschhäuser; F Lottspeich; K Jann; Jörg Hacker
Analysis of genes coding for the sialic acid-binding adhesin and two other minor fimbrial subunits of the S-fimbrial adhesin determinant of Escherichia coli.
Molecular microbiology 1989;3(12):1735-44.