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Stergios Moschos

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Kerstin Trunzer; Jeffrey S Weber; Annette Schell-Steven; Lynn Schuchter; Jeffrey A Sosman; Olivia Spleiss; Ravi K Amaravadi; Gideon Bollag; Louise Cockey; Keith T Flaherty; Houston N Gilbert; Rene Gonzalez; Peter Hersey; Thomas E Hutson; Andrew K Joe; Kevin B Kim; Mark Kockx; Astrid Koehler; Donald Lawrence; Richard J Lee; Karl D Lewis; Roger S Lo; Georgina V Long; Grant A McArthur; Stergios J Moschos; Patrick A Ott; Anna C Pavlick; Igor Puzanov; Antoni Ribas
Pharmacodynamic effects and mechanisms of resistance to vemurafenib in patients with metastatic melanoma.
Jennifer Schlegel; Janiel M Shields; Aik Choon Tan; John J Tentler; Dimitri G Trembath; Xiaodong Wang; Amanda Winges; Chao Yang; Weihe Zhang; Ronald L Hamilton; Pei-Fen Kuan; Jing Liu; Bentley R Midkiff; C Ryan Miller; Stergios J Moschos; Nana Nikolaishvili-Feinberg; Maria J Sambade; Susan Sather; Craig C Carson; Deborah DeRyckere; Lyn M Duncan; H Shelton Earp; S Gail Eckhardt; Stephen V Frye; Douglas K Graham
MERTK receptor tyrosine kinase is a therapeutic target in melanoma.
Sara C Hanna; Sean T Bailey; Lyn M Duncan; Bhavani Krishnan; Pei-Fen Kuan; C Ryan Miller; Stergios J Moschos; E Tim O'Brien; Lukas D Osborne; Takeshi Shimamura; Marni B Siegel; M Celeste Simon; Richard Superfine; Kwok-Kin Wong; William Y Kim
HIF1α and HIF2α independently activate SRC to promote melanoma metastases.

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2013: Kerstin Trunzer; Jeffrey S Weber; Annette Schell-Steven; Lynn Schuchter; Jeffrey A Sosman; Olivia Spleiss; Ravi K Amaravadi; Gideon Bollag; Louise Cockey; Keith T Flaherty; Houston N Gilbert; Rene Gonzalez; Peter Hersey; Thomas E Hutson; Andrew K Joe; Kevin B Kim; Mark Kockx; Astrid Koehler; Donald Lawrence; Richard J Lee; Karl D Lewis; Roger S Lo; Georgina V Long; Grant A McArthur; Stergios J Moschos; Patrick A Ott; Anna C Pavlick; Igor Puzanov; Antoni Ribas
Pharmacodynamic effects and mechanisms of resistance to vemurafenib in patients with metastatic melanoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2013;31(14):1767-74.
2013: Jennifer Schlegel; Janiel M Shields; Aik Choon Tan; John J Tentler; Dimitri G Trembath; Xiaodong Wang; Amanda Winges; Chao Yang; Weihe Zhang; Ronald L Hamilton; Pei-Fen Kuan; Jing Liu; Bentley R Midkiff; C Ryan Miller; Stergios J Moschos; Nana Nikolaishvili-Feinberg; Maria J Sambade; Susan Sather; Craig C Carson; Deborah DeRyckere; Lyn M Duncan; H Shelton Earp; S Gail Eckhardt; Stephen V Frye; Douglas K Graham
MERTK receptor tyrosine kinase is a therapeutic target in melanoma.
The Journal of clinical investigation 2013;123(5):2257-67.
2013: Sara C Hanna; Sean T Bailey; Lyn M Duncan; Bhavani Krishnan; Pei-Fen Kuan; C Ryan Miller; Stergios J Moschos; E Tim O'Brien; Lukas D Osborne; Takeshi Shimamura; Marni B Siegel; M Celeste Simon; Richard Superfine; Kwok-Kin Wong; William Y Kim
HIF1α and HIF2α independently activate SRC to promote melanoma metastases.
The Journal of clinical investigation 2013;123(5):2078-93.
2013: Hussein Tawbi; Y Lin; Stergios J Moschos; Ahmad A Tarhini; Jan H Beumer; Shama C Buch; S Christner; M J Egorin; J M Kirkwood
Safety and efficacy of decitabine in combination with temozolomide in metastatic melanoma: a phase I/II study and pharmacokinetic analysis.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2013;24(4):1112-9.
2012: Ahmad A Tarhini; Yan Yin; William E Gooding; Siyang Leng; Yan Lin; Stergios J Moschos; Cindy Sander; John M Kirkwood
Safety and immunogenicity of vaccination with MART-1 (26-35, 27L), gp100 (209-217, 210M), and tyrosinase (368-376, 370D) in adjuvant with PF-3512676 and GM-CSF in metastatic melanoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2012;35(4):359-66.
2012: Jeffrey A Sosman; Jeffrey S Weber; Fei Ye; Lynn Schuchter; Yu Shyr; Ravi K Amaravadi; Bartosz Chmielowski; Keith T Flaherty; Rene Gonzalez; Peter Hersey; Thomas E Hutson; Andrew K Joe; Richard Kefford; Kevin B Kim; Donald Lawrence; H Jeffrey Lawrence; Richard J Lee; Karl D Lewis; Jiang Li; Grant A McArthur; Stergios J Moschos; Keith B Nolop; Anna C Pavlick; Igor Puzanov; Antoni Ribas
Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib.
The New England journal of medicine 2012;366(8):707-14.
2012: Ahmad A Tarhini; Hussein Tawbi; John Cherian; William Gooding; Stergios J Moschos; Cindy Sander; Yongli Shuai; John M Kirkwood
Safety and efficacy of combination immunotherapy with interferon alfa-2b and tremelimumab in patients with stage IV melanoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(3):322-8.
2012: Jonhan Ho; Lin Hui-Min; John M Kirkwood; Yan Lin; Dorothea Becker; Michelle Barbi de Moura; Lyn M Duncan; Stephen Thorne; Bennett Van Houten; Garret Vincent; Stergios J Moschos
Importance of glycolysis and oxidative phosphorylation in advanced melanoma.
Molecular cancer 2012;11():76.
2012: Michelle Barbi de Moura; Nicholas W Bateman; Dorothea Becker; Thomas P Conrads; Stefan Duensing; Shelley L Fayewicz; Brian L Hood; John M Kirkwood; Cindy Sander; Joseph Suhan; Mai Sun; Bennett Van Houten; Garret Vincent; Yan Yin; Stergios J Moschos
Mitochondrial respiration--an important therapeutic target in melanoma.
PloS one 2012;7(8):e40690.
2011: Hussein Tawbi; L Villaruz; F Viverette; Stergios J Moschos; R Radkowski; Janice Shipe-Spotloe; M Sulecki; Ahmad A Tarhini; John M Kirkwood
Inhibition of DNA repair with MGMT pseudosubstrates: phase I study of lomeguatrib in combination with dacarbazine in patients with advanced melanoma and other solid tumours.
British journal of cancer 2011;105(6):773-7.
2011: Jeffrey L Wong; Robbie B Mailliard; Stergios J Moschos; Howard Edington; Michael T Lotze; John M Kirkwood; Pawel Kalinski
Helper activity of natural killer cells during the dendritic cell-mediated induction of melanoma-specific cytotoxic T cells.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2011;34(3):270-8.
2010: Xiaolei Wang; Stergios J Moschos; Dorothea Becker
Functional analysis and molecular targeting of aurora kinases a and B in advanced melanoma.
Genes & cancer 2010;1(9):952-63.
2010: Stergios J Moschos; Drazen M Jukic; Charalambos Athanassiou; Rohit Bhargava; Sanja Dacic; Xiaolei Wang; Shih-Fan Kuan; Shelley L Fayewicz; Csaba Galambos; Marie Acquafondata; Rajiv Dhir; Dorothea Becker
Expression analysis of Ubc9, the single small ubiquitin-like modifier (SUMO) E2 conjugating enzyme, in normal and malignant tissues.
Human pathology 2010;41(9):1286-98.
2010: Stergios J Moschos; Cindy A Sander; Wenjun Wang; Shelley L Reppert; Laura M Drogowski; Drazen M Jukic; Uma N M Rao; Charalambos Athanassiou; Manuela Buzoianu; Maja Mandic; Laura K Richman; LuAnn McKinney; Joel Leininger; David A Tice; Luz D Hammershaimb; John M Kirkwood
Pharmacodynamic (phase 0) study using etaracizumab in advanced melanoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2010;33(3):316-25.
2009: Stergios J Moschos; Nicole R Dodd; Drazen M Jukic; Shelley L Fayewicz; Xiaolei Wang; Dorothea Becker
Suppressing the high-level expression and function of ATM in advanced-stage melanomas does not sensitize the cells to ionizing radiation.
Cancer biology & therapy 2009;8(19):1815-25.
2009: Yanis L Tolstov; Diana V Pastrana; Huichen Feng; Jürgen C Becker; Frank J Jenkins; Stergios J Moschos; Yuan Chang; Christopher B Buck; Patrick S Moore
Human Merkel cell polyomavirus infection II. MCV is a common human infection that can be detected by conformational capsid epitope immunoassays.
International journal of cancer. Journal international du cancer 2009;125(6):1250-6.
2009: Michalis V Karamouzis; Stergios J Moschos
The use of endostatin in the treatment of solid tumors.
Expert opinion on biological therapy 2009;9(5):641-8.
2009: John M Kirkwood; Hussein Tawbi; Ahmad A Tarhini; Stergios J Moschos
Does pegylated interferon alpha-2b confer additional benefit in the adjuvant treatment of high-risk melanoma?
Nature clinical practice. Oncology 2009;6(2):70-1.
2008: John M Kirkwood; Ahmad A Tarhini; Monica C Panelli; Stergios J Moschos; Hassane M Zarour; Lisa H Butterfield; Helen J Gogas
Next generation of immunotherapy for melanoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(20):3445-55.
2008: Stergios J Moschos; Preet M Chaudhary; John M Kirkwood
Resolving "kinks" of chemotherapy in melanoma.
Journal of the National Cancer Institute 2008;100(12):833-5.
2008: Stergios J Moschos; Maja Mandic; John M Kirkwood; Walter J Storkus; Michael T Lotze
Focus on FOCIS: interleukin 2 treatment associated autoimmunity.
Clinical immunology (Orlando, Fla.) 2008;127(2):123-9.
2008: John M Kirkwood; Ahmad A Tarhini; Stergios J Moschos; Monica C Panelli
Adjuvant therapy with high-dose interferon alpha 2b in patients with high-risk stage IIB/III melanoma.
Nature clinical practice. Oncology 2008;5(1):2-3.
2007: Stergios J Moschos; John M Kirkwood
Present role and future potential of type I interferons in adjuvant therapy of high-risk operable melanoma.
Cytokine & growth factor reviews 2007;18(5-6):451-8.
2007: Stergios J Moschos; Laura M Drogowski; Shelley L Reppert; John M Kirkwood
Integrins and cancer.
Oncology (Williston Park, N.Y.) 2007;21(9 Suppl 3):13-20.
2007: Stergios J Moschos; Amanda Pfaff Smith; Maja Mandic; C Athanassiou; K Watson-Hurst; Drazen M Jukic; Howard D Edington; John M Kirkwood; D Becker
SAGE and antibody array analysis of melanoma-infiltrated lymph nodes: identification of Ubc9 as an important molecule in advanced-stage melanomas.
Oncogene 2007;26(29):4216-25.
2007: Stergios J Moschos; Christine Odoux; Stephanie R Land; Sanjiv Agarwala; David M Friedland; Kirk M Volker; Carolyn Sidor; Michael Wong; John M Kirkwood
Endostatin plus interferon-alpha2b therapy for metastatic melanoma: a novel combination of antiangiogenic and immunomodulatory agents.
Melanoma research 2007;17(3):193-200.
2006: Stergios J Moschos; Yin-Yuan Mo
Role of SUMO/Ubc9 in DNA damage repair and tumorigenesis.
Journal of molecular histology 2006;37(5-7):309-19.
2006: Stergios J Moschos; Howard D Edington; Stephanie R Land; Uma N M Rao; Drazen M Jukic; Janice Shipe-Spotloe; John M Kirkwood
Neoadjuvant treatment of regional stage IIIB melanoma with high-dose interferon alfa-2b induces objective tumor regression in association with modulation of tumor infiltrating host cellular immune responses.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(19):3164-71.
2006: John M Kirkwood; Stergios J Moschos; Wenjun Wang
Strategies for the development of more effective adjuvant therapy of melanoma: current and future explorations of antibodies, cytokines, vaccines, and combinations.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(7 Pt 2):2331s-2336s.
2005: Yin-Yuan Mo; Stergios J Moschos
Targeting Ubc9 for cancer therapy.
Expert opinion on therapeutic targets 2005;9(6):1203-16.
2005: Jean L Chan; Stergios J Moschos; John Bullen; Kathleen Heist; Xian Li; Young-Bum Kim; Barbara B Kahn; Christos S Mantzoros
Recombinant methionyl human leptin administration activates signal transducer and activator of transcription 3 signaling in peripheral blood mononuclear cells in vivo and regulates soluble tumor necrosis factor-alpha receptor levels in humans with relative leptin deficiency.
The Journal of clinical endocrinology and metabolism 2005;90(3):1625-31.
2005: Stergios J Moschos; Sai Varanasi; John M Kirkwood
Interferons in the treatment of solid tumors.
Cancer treatment and research 2005;126():207-41.
2005: Stergios J Moschos; Panagiotis A Konstantinopoulos; John M Kirkwood
Melanoma.
Cancer chemotherapy and biological response modifiers 2005;22():563-90.
2004: Susann Blüher; Stergios J Moschos; John Bullen; Efi Kokkotou; Eleftheria Maratos-Flier; Stanley J Wiegand; Mark W Sleeman; Mark W Sleemann; Christos S Mantzoros
Ciliary neurotrophic factorAx15 alters energy homeostasis, decreases body weight, and improves metabolic control in diet-induced obese and UCP1-DTA mice.
Diabetes 2004;53(11):2787-96.
2004: Susann Blüher; Mary Ziotopoulou; John Bullen; Stergios J Moschos; Linda Ungsunan; Efi Kokkotou; Eleftheria Maratos-Flier; Christos S Mantzoros
Responsiveness to peripherally administered melanocortins in lean and obese mice.
Diabetes 2004;53(1):82-90.
2004: Stergios J Moschos; John M Kirkwood; Panagiotis A Konstantinopoulos
Present status and future prospects for adjuvant therapy of melanoma: time to build upon the foundation of high-dose interferon alfa-2b.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(1):11-4.
2002: Dominique D Pierroz; Mary Ziotopoulou; Linda Ungsunan; Stergios J Moschos; Jeffrey S Flier; Christos S Mantzoros
Effects of acute and chronic administration of the melanocortin agonist MTII in mice with diet-induced obesity.
Diabetes 2002;51(5):1337-45.
2002: Stergios J Moschos; Jean L Chan; Christos S Mantzoros
Leptin and reproduction: a review.
Fertility and sterility 2002;77(3):433-44.
2002: Stergios J Moschos; Christos S Mantzoros
The role of the IGF system in cancer: from basic to clinical studies and clinical applications.
Oncology 2002;63(4):317-32.
1999: Christos S Mantzoros; K Bolhke; Stergios J Moschos; D W Cramer
Leptin in relation to carcinoma in situ of the breast: a study of pre-menopausal cases and controls.
International journal of cancer. Journal international du cancer 1999;80(4):523-6.
1998: Christos S Mantzoros; Stergios J Moschos
Leptin: in search of role(s) in human physiology and pathophysiology.
Clinical endocrinology 1998;49(5):551-67.