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Christopher Moser

Research Profile

Chemicals & Drugs

Phenomena

Physiology

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Rhodobacter capsulatus

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Thermodynamics

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Publications

TOP 3
Bruce R Lichtenstein; Joshua A Mancini; Christopher C Moser; Molly M Sheehan; David Snell; Lee A Solomon; Sergei A Vinogradov; Zhenyu Zhao; J L Ross Anderson; Craig T Armstrong; Chris Bialas; Sarah E Chobot; Bohdana M Discher; Nathan M Ennist; Tatiana V Esipova; Tammer A Farid; Bryan A Fry; Goutham Kodali; P Leslie Dutton
Engineering oxidoreductases: maquette proteins designed from scratch.
P Leslie Dutton; Christopher C Moser
Engineering enzymes.
Christopher C Moser; J L Ross Anderson; P Leslie Dutton
Guidelines for tunneling in enzymes.

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All Publications

2012: Bruce R Lichtenstein; Joshua A Mancini; Christopher C Moser; Molly M Sheehan; David Snell; Lee A Solomon; Sergei A Vinogradov; Zhenyu Zhao; J L Ross Anderson; Craig T Armstrong; Chris Bialas; Sarah E Chobot; Bohdana M Discher; Nathan M Ennist; Tatiana V Esipova; Tammer A Farid; Bryan A Fry; Goutham Kodali; P Leslie Dutton
Engineering oxidoreductases: maquette proteins designed from scratch.
Biochemical Society transactions 2012;40(3):561-6.
2011: P Leslie Dutton; Christopher C Moser
Engineering enzymes.
Faraday discussions 2011;148():443-8.
2010: Christopher C Moser; J L Ross Anderson; P Leslie Dutton
Guidelines for tunneling in enzymes.
Biochimica et biophysica acta 2010;1797(9):1573-86.
2009: Ronald Koder; J L Ross Anderson; Lee A Solomon; Konda S Reddy; Christopher C Moser; P Leslie Dutton
Design and engineering of an O(2) transport protein.
Nature 2009;458(7236):305-9.
2008: J L Ross Anderson; Ronald Koder; Christopher C Moser; P Leslie Dutton
Controlling complexity and water penetration in functional de novo protein design.
Biochemical Society transactions 2008;36(Pt 6):1106-11.
2008: Haibo Zhang; Sarah E Chobot; Artur Osyczka; Colin A Wraight; P Leslie Dutton; Christopher C Moser
Quinone and non-quinone redox couples in Complex III.
Journal of bioenergetics and biomembranes 2008;40(5):493-9.
2008: Sarah E Chobot; Haibo Zhang; Christopher C Moser; P Leslie Dutton
Breaking the Q-cycle: finding new ways to study Qo through thermodynamic manipulations.
Journal of bioenergetics and biomembranes 2008;40(5):501-7.
2008: Christopher C Moser; Sarah E Chobot; Christopher C Page; P Leslie Dutton
Distance metrics for heme protein electron tunneling.
Biochimica et biophysica acta 2008;1777(7-8):1032-7.
2007: Haibo Zhang; Artur Osyczka; P Leslie Dutton; Christopher C Moser
Exposing the complex III Qo semiquinone radical.
Biochimica et biophysica acta 2007;1767(7):883-7.
2006: Haibo Zhang; Artur Osyczka; Christopher C Moser; P Leslie Dutton
Resilience of Rhodobacter sphaeroides cytochrome bc1 to heme c1 ligation changes.
Biochemistry 2006;45(48):14247-55.
2006: Artur Osyczka; Haibo Zhang; Christelle Mathé; Peter R Rich; Christopher C Moser; P Leslie Dutton
Role of the PEWY glutamate in hydroquinone-quinone oxidation-reduction catalysis in the Qo Site of cytochrome bc1.
Biochemistry 2006;45(35):10492-503.
2006: Christopher C Moser; Tammer A Farid; Sarah E Chobot; P Leslie Dutton
Electron tunneling chains of mitochondria.
Biochimica et biophysica acta 2006;1757(9-10):1096-109.
2006: Christopher C Moser; Christopher C Page; P Leslie Dutton
Darwin at the molecular scale: selection and variance in electron tunnelling proteins including cytochrome c oxidase.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2006;361(1472):1295-305.
2006: Dror Noy; Christopher C Moser; P Leslie Dutton
Design and engineering of photosynthetic light-harvesting and electron transfer using length, time, and energy scales.
Biochimica et biophysica acta 2006;1757(2):90-105.
2005: Christopher C Moser; Christopher C Page; P Leslie Dutton
Tunneling in PSII.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2005;4(12):933-9.
2005: Bohdana M Discher; Dror Noy; Joseph Strzalka; Shixin Ye; Christopher C Moser; James D Lear; J Kent Blasie; P Leslie Dutton
Design of amphiphilic protein maquettes: controlling assembly, membrane insertion, and cofactor interactions.
Biochemistry 2005;44(37):12329-43.
2005: Artur Osyczka; Christopher C Moser; P Leslie Dutton
Fixing the Q cycle.
Trends in biochemical sciences 2005;30(4):176-82.
2004: Masayo Iwaki; Artur Osyczka; Christopher C Moser; P Leslie Dutton; Peter R Rich
ATR-FTIR spectroscopy studies of iron-sulfur protein and cytochrome c1 in the Rhodobacter capsulatus cytochrome bc1 complex.
Biochemistry 2004;43(29):9477-86.
2004: Artur Osyczka; Christopher C Moser; P Leslie Dutton
Novel cyanide inhibition at cytochrome c1 of Rhodobacter capsulatus cytochrome bc1.
Biochimica et biophysica acta 2004;1655(1-3):71-6.
2004: Artur Osyczka; Christopher C Moser; Fevzi Daldal; P Leslie Dutton
Reversible redox energy coupling in electron transfer chains.
Nature 2004;427(6975):607-12.
2003: Emmanuel Topoglidis; Bohdana M Discher; Christopher C Moser; P Leslie Dutton; James R Durrant
Functionalizing nanocrystalline metal oxide electrodes with robust synthetic redox proteins.
Chembiochem : a European journal of chemical biology 2003;4(12):1332-9.
2003: Bohdana M Discher; Ronald Koder; Christopher C Moser; P Leslie Dutton
Hydrophilic to amphiphilic design in redox protein maquettes.
Current opinion in chemical biology 2003;7(6):741-8.
2003: Christopher C Page; Christopher C Moser; P Leslie Dutton
Mechanism for electron transfer within and between proteins.
Current opinion in chemical biology 2003;7(5):551-6.
2003: Christopher C Moser; Christopher C Page; Richard J Cogdell; James Barber; Colin A Wraight; P Leslie Dutton
Length, time, and energy scales of photosystems.
Advances in protein chemistry 2003;63():71-109.
2002: Andrew W Munro; David G Leys; Kirsty J McLean; Ker R Marshall; Tobias W B Ost; Simon Daff; Caroline S Miles; Stephen K Chapman; Dominikus Lysek; Christopher C Moser; Christopher C Page; P Leslie Dutton
P450 BM3: the very model of a modern flavocytochrome.
Trends in biochemical sciences 2002;27(5):250-7.
2001: Artur Osyczka; P Leslie Dutton; Christopher C Moser; Elisabeth Darrouzet; Fevzi Daldal
Controlling the functionality of cytochrome c(1) redox potentials in the Rhodobacter capsulatus bc(1) complex through disulfide anchoring of a loop and a beta-branched amino acid near the heme-ligating methionine.
Biochemistry 2001;40(48):14547-56.
2001: Elisabeth Darrouzet; Christopher C Moser; P Leslie Dutton; Fevzi Daldal
Large scale domain movement in cytochrome bc(1): a new device for electron transfer in proteins.
Trends in biochemical sciences 2001;26(7):445-51.
2001: A M Grosset; Brian R Gibney; F Rabanal; Christopher C Moser; P Leslie Dutton
Proof of principle in a de novo designed protein maquette: an allosterically regulated, charge-activated conformational switch in a tetra-alpha-helix bundle.
Biochemistry 2001;40(18):5474-87.
2000: Brian R Gibney; Y Isogai; F Rabanal; Konda S Reddy; A M Grosset; Christopher C Moser; P Leslie Dutton
Self-assembly of heme A and heme B in a designed four-helix bundle: implications for a cytochrome c oxidase maquette.
Biochemistry 2000;39(36):11041-9.
2000: Elisabeth Darrouzet; Maria Valkova-Valchanova; Christopher C Moser; P Leslie Dutton; Fevzi Daldal
Uncovering the [2Fe2S] domain movement in cytochrome bc1 and its implications for energy conversion.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(9):4567-72.
2000: Tomoko Ohnishi; Christopher C Moser; Christopher C Page; P Leslie Dutton; Takahiro Yano
Simple redox-linked proton-transfer design: new insights from structures of quinol-fumarate reductase.
Structure (London, England : 1993) 2000;8(2):R23-32.
2000: Christopher C Moser; Christopher C Page; X Chen; P Leslie Dutton
Electron transfer in natural proteins theory and design.
Sub-cellular biochemistry 2000;35():1-28.
1999: RE Sharp; Brian R Gibney; A Palmitessa; J L White; J A Dixon; Christopher C Moser; Fevzi Daldal; P Leslie Dutton
Effect of inhibitors on the ubiquinone binding capacity of the primary energy conversion site in the Rhodobacter capsulatus cytochrome bc(1) complex.
Biochemistry 1999;38(45):14973-80.
1999: Christopher C Page; Christopher C Moser; X Chen; P Leslie Dutton
Natural engineering principles of electron tunnelling in biological oxidation-reduction.
Nature 1999;402(6757):47-52.
1999: RE Sharp; A Palmitessa; Brian R Gibney; Christopher C Moser; P Leslie Dutton
Probing the ubihydroquinone primary energy conversion site in the Rhodobacter capsulatus cytochrome bc1 complex.
Biochemical Society transactions 1999;27(4):572-6.
1999: RE Sharp; Christopher C Moser; Brian R Gibney; P Leslie Dutton
Primary steps in the energy conversion reaction of the cytochrome bc1 complex Qo site.
Journal of bioenergetics and biomembranes 1999;31(3):225-33.
1999: RE Sharp; A Palmitessa; Brian R Gibney; J L White; Christopher C Moser; Fevzi Daldal; P Leslie Dutton
Ubiquinone binding capacity of the Rhodobacter capsulatus cytochrome bc1 complex: effect of diphenylamine, a weak binding QO site inhibitor.
Biochemistry 1999;38(11):3440-6.
1998: J M Shifman; Christopher C Moser; W A Kalsbeck; David F Bocian; P Leslie Dutton
Functionalized de novo designed proteins: mechanism of proton coupling to oxidation/reduction in heme protein maquettes.
Biochemistry 1998;37(47):16815-27.
1998: RE Sharp; Christopher C Moser; F Rabanal; P Leslie Dutton
Design, synthesis, and characterization of a photoactivatable flavocytochrome molecular maquette.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(18):10465-70.
1998: RE Sharp; A Palmitessa; Brian R Gibney; Christopher C Moser; Fevzi Daldal; P Leslie Dutton
Non-inhibiting perturbation of the primary energy conversion site (Qo site) in Rhodobacter capsulatus ubihydroquinone: cytochrome c oxidoreductase (cytochrome bc1 complex).
FEBS letters 1998;431(3):423-6.
1998: P Leslie Dutton; Christopher C Moser; Vladimir D Sled; Fevzi Daldal; Tomoko Ohnishi
A reductant-induced oxidation mechanism for complex I.
Biochimica et biophysica acta 1998;1364(2):245-57.
1995: H Ding; Christopher C Moser; D E Robertson; Mariko Tokito; Fevzi Daldal; P Leslie Dutton
Ubiquinone pair in the Qo site central to the primary energy conversion reactions of cytochrome bc1 complex.
Biochemistry 1995;34(49):15979-96.
1995: Christopher C Moser; C C Page; R Farid; P Leslie Dutton
Biological electron transfer.
Journal of bioenergetics and biomembranes 1995;27(3):263-74.
1994: S Maiti; G C Walker; B R Cowen; R Pippenger; Christopher C Moser; P Leslie Dutton; Robin M Hochstrasser
Femtosecond coherent transient infrared spectroscopy of reaction centers from Rhodobacter sphaeroides.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(22):10360-4.
1994: R S Farid; D E Robertson; Christopher C Moser; D Pilloud; W F DeGrado; P Leslie Dutton
Design and synthesis of simplified energy-converting proteins.
Biochemical Society transactions 1994;22(3):689-93.
1994: D E Robertson; R S Farid; Christopher C Moser; Jeffrey L Urbauer; S E Mulholland; R Pidikiti; James D Lear; A Joshua Wand; W F DeGrado; P Leslie Dutton
Design and synthesis of multi-haem proteins.
Nature 1994;368(6470):425-32.
1993: S Maiti; B R Cowen; R Diller; M Iannone; Christopher C Moser; P Leslie Dutton; Robin M Hochstrasser
Picosecond infrared studies of the dynamics of the photosynthetic reaction center.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(11):5247-51.
1992: Christopher C Moser; P Leslie Dutton
Engineering protein structure for electron transfer function in photosynthetic reaction centers.
Biochimica et biophysica acta 1992;1101(2):171-6.
1992: Christopher C Moser; J M Keske; Kurt Warncke; R S Farid; P Leslie Dutton
Nature of biological electron transfer.
Nature 1992;355(6363):796-802.
1988: Christopher C Moser; P Leslie Dutton
Cytochrome c and c2 binding dynamics and electron transfer with photosynthetic reaction center protein and other integral membrane redox proteins.
Biochemistry 1988;27(7):2450-61.
1984: D E Robertson; K M Giangiacomo; S de Vries; Christopher C Moser; P Leslie Dutton
Two distinct quinone-modulated modes of antimycin-sensitive cytochrome b reduction in the cytochrome bc1 complex.
FEBS letters 1984;178(2):343-50.