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Harold Moses

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Chemicals & Drugs

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Cell Transformation, Neoplastic

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Sergey V Novitskiy; Philip Owens; Michael W Pickup; Dina Polosukhina; Anna Chytil; Harold L Moses
Deletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties.
Sergey V Novitskiy; Harold L Moses
Turn off the IDO: will clinical trials be successful?
Sarah J Kurley; Nichole A Lobdell; Harold L Moses; William J Muller; Brian Bierie; Robert H Carnahan; Michael A Davis; Ilse Hofmann; Albert B Reynolds
p120-catenin is essential for terminal end bud function and mammary morphogenesis.

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All Publications

2012: Sergey V Novitskiy; Philip Owens; Michael W Pickup; Dina Polosukhina; Anna Chytil; Harold L Moses
Deletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties.
Journal of leukocyte biology 2012;92(3):641-51.
2012: Sergey V Novitskiy; Harold L Moses
Turn off the IDO: will clinical trials be successful?
Cancer discovery 2012;2(8):673-5.
2012: Sarah J Kurley; Nichole A Lobdell; Harold L Moses; William J Muller; Brian Bierie; Robert H Carnahan; Michael A Davis; Ilse Hofmann; Albert B Reynolds
p120-catenin is essential for terminal end bud function and mammary morphogenesis.
Development (Cambridge, England) 2012;139(10):1754-64.
2011: Peter E Clark; Cheryl Coffin; Hernan Correa; Mark de Caestecker; Harold Love; Harold L Moses; Elizabeth J Perlman; Dina Polosukhina; Roy Zent
β-Catenin and K-RAS synergize to form primitive renal epithelial tumors with features of epithelial Wilms' tumors.
The American journal of pathology 2011;179(6):3045-55.
2011: Sergey V Novitskiy; Philip Owens; Michael W Pickup; Yu Shyr; Huiyun Wu; Mary E Aakre; Anna Chytil; Agnieszka E Gorska; Harold L Moses
TGF-β receptor II loss promotes mammary carcinoma progression by Th17 dependent mechanisms.
Cancer discovery 2011;1(5):430-41.
2010: Peter E Clark; Dina A Polosukhina; Kenneth Gyabaah; Harold L Moses; Andrew Thorburn; Roy Zent
TRAIL and interferon-alpha act synergistically to induce renal cell carcinoma apoptosis.
The Journal of urology 2010;184(3):1166-74.
2010: Leslie Gewin; Nada Bulus; Glenda Mernaugh; Gilbert W Moeckel; Raymond C Harris; Harold L Moses; Ambra Pozzi; Roy Zent
TGF-beta receptor deletion in the renal collecting system exacerbates fibrosis.
Journal of the American Society of Nephrology : JASN 2010;21(8):1334-43.
2010: Baogang J Xu; Wenwei Yan; Bojana Jovanovic; Angel Q An; Nikki Cheng; Mary E Aakre; Yajun Yi; Jimmy Eng; Andrew J Link; Harold L Moses
Quantitative analysis of the secretome of TGF-beta signaling-deficient mammary fibroblasts.
Proteomics 2010;10(13):2458-70.
2010: Brian Bierie; Harold L Moses
Transforming growth factor beta (TGF-beta) and inflammation in cancer.
Cytokine & growth factor reviews 2010;21(1):49-59.
2009: Lauren A Matise; Michael W Pickup; Harold L Moses
TGF-beta helps cells fly solo.
Nature cell biology 2009;11(11):1281-4.
2009: Brian Bierie; Harold L Moses
Gain or loss of TGFbeta signaling in mammary carcinoma cells can promote metastasis.
Cell cycle (Georgetown, Tex.) 2009;8(20):3319-27.
2009: Brian Bierie; Christine H Chung; Joel Parker; Daniel G Stover; Nikki Cheng; Anna Chytil; Mary Aakre; Yu Shyr; Harold L Moses
Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancer.
The Journal of clinical investigation 2009;119(6):1571-82.
2009: Ty W Abel; Cara Clark; Brian Bierie; Anna Chytil; Mary Aakre; Agnieszka Gorska; Harold L Moses
GFAP-Cre-mediated activation of oncogenic K-ras results in expansion of the subventricular zone and infiltrating glioma.
Molecular cancer research : MCR 2009;7(5):645-53.
2009: Brian Bierie; Agnieszka E Gorska; Daniel G Stover; Harold L Moses
TGF-beta promotes cell death and suppresses lactation during the second stage of mammary involution.
Journal of cellular physiology 2009;219(1):57-68.
2008: Li Yang; Harold L Moses
Transforming growth factor beta: tumor suppressor or promoter? Are host immune cells the answer?
Cancer research 2008;68(22):9107-11.
2008: Mete Erdogan; Ambra Pozzi; Neil A Bhowmick; Harold L Moses; Roy Zent
Transforming growth factor-beta (TGF-beta) and TGF-beta-associated kinase 1 are required for R-Ras-mediated transformation of mammary epithelial cells.
Cancer research 2008;68(15):6224-31.
2008: Brian Bierie; Daniel G Stover; Ty W Abel; Anna Chytil; Agnieszka E Gorska; Mary E Aakre; Elizabeth Forrester; Li Yang; Kay-Uwe Wagner; Harold L Moses
Transforming growth factor-beta regulates mammary carcinoma cell survival and interaction with the adjacent microenvironment.
Cancer research 2008;68(6):1809-19.
2008: Li Yang; Jianhua Huang; Xiubao Ren; Agnieszka E Gorska; Anna Chytil; Mary E Aakre; David P Carbone; Lynn M Matrisian; Ann Richmond; P Charles Lin; Harold L Moses
Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis.
Cancer cell 2008;13(1):23-35.
2007: Mete Erdogan; Ambra Pozzi; Neil A Bhowmick; Harold L Moses; Roy Zent
Signaling pathways regulating TC21-induced tumorigenesis.
The Journal of biological chemistry 2007;282(38):27713-20.
2007: Daniel G Stover; Brian Bierie; Harold L Moses
A delicate balance: TGF-beta and the tumor microenvironment.
Journal of cellular biochemistry 2007;101(4):851-61.
2007: Anna Spagnoli; Lynda O'Rear; Ronald L. Chandler; Froilan Granero-Molto; Douglas P Mortlock; Agnieszka E Gorska; Jared A Weis; Lara Longobardi; Anna Chytil; Kimberly Shimer; Harold L Moses
TGF-beta signaling is essential for joint morphogenesis.
The Journal of cell biology 2007;177(6):1105-17.
2007: Nikki Cheng; Anna Chytil; Yu Shyr; Alison Joly; Harold L Moses
Enhanced hepatocyte growth factor signaling by type II transforming growth factor-beta receptor knockout fibroblasts promotes mammary tumorigenesis.
Cancer research 2007;67(10):4869-77.
2007: Swati Biswas; Marta Guix; Cammie Rinehart; Teresa C Dugger; Anna Chytil; Harold L Moses; Michael L Freeman; Carlos L Arteaga
Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression.
The Journal of clinical investigation 2007;117(5):1305-13.
2007: Kimberly A Brown; Jennifer A Pietenpol; Harold L Moses
A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling.
Journal of cellular biochemistry 2007;101(1):9-33.
2007: Alyssa R Bonine-Summers; Mary E Aakre; Kimberly A Brown; Carlos L Arteaga; Jennifer A Pietenpol; Harold L Moses; Nikki Cheng
Epidermal growth factor receptor plays a significant role in hepatocyte growth factor mediated biological responses in mammary epithelial cells.
Cancer biology & therapy 2007;6(4):561-70.
2007: Elizabeth Harper; Harold L Moses; Andre H Lagrange
Occult celiac disease presenting as epilepsy and MRI changes that responded to gluten-free diet.
Neurology 2007;68(7):533-4.
2007: Arichika Hoshino; Cindy J Yee; Mel Campbell; Randall L Woltjer; Rebecca L Townsend; Riet Van Der Meer; Yu Shyr; Jeffrey T Holt; Harold L Moses; Roy A Jensen
Effects of BRCA1 transgene expression on murine mammary gland development and mutagen-induced mammary neoplasia.
International journal of biological sciences 2007;3(5):281-91.
2007: Etienne Labbé; Lisa Lock; Ainhoa Letamendia; Agnieszka E Gorska; Robert Gryfe; Steven Gallinger; Harold L Moses; Liliana Attisano
Transcriptional cooperation between the transforming growth factor-beta and Wnt pathways in mammary and intestinal tumorigenesis.
Cancer research 2007;67(1):75-84.
2006: Hideaki Ijichi; Anna Chytil; Agnieszka E Gorska; Mary E Aakre; Yoshio Fujitani; Shuko Fujitani; Christopher V E Wright; Harold L Moses
Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression.
Genes & development 2006;20(22):3147-60.
2006: Nina M Muñoz; Melissa Upton; Andres Rojas; M Kay Washington; Li Lin; Anna Chytil; Elif G Sozmen; Blair B Madison; Ambra Pozzi; Randall T Moon; Harold L Moses; William M Grady
Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation.
Cancer research 2006;66(20):9837-44.
2006: Brian Bierie; Harold L Moses
Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer.
Nature reviews. Cancer 2006;6(7):506-20.
2006: Sunil K Halder; Govindaraj Anumanthan; Ramakoti Maddula; Jason Mann; Anna Chytil; Adriana L Gonzalez; M Kay Washington; Harold L Moses; R Daniel Beauchamp; Pran K Datta
Oncogenic function of a novel WD-domain protein, STRAP, in human carcinogenesis.
Cancer research 2006;66(12):6156-66.
2006: Lara Longobardi; Lynda O'Rear; Srikanth Aakula; Brian Johnstone; Kimberly Shimer; Anna Chytil; William A Horton; Harold L Moses; Anna Spagnoli
Effect of IGF-I in the chondrogenesis of bone marrow mesenchymal stem cells in the presence or absence of TGF-beta signaling.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21(4):626-36.
2006: Brian Bierie; Harold L Moses
TGF-beta and cancer.
Cytokine & growth factor reviews 2006;17(1-2):29-40.
2005: Brian Bierie; Harold L Moses
Under pressure: stromal fibroblasts change their ways.
Cell 2005;123(6):985-7.
2005: Lu Xie; Baogang J Xu; Agnieszka E Gorska; Yu Shyr; Sarah A Schwartz; Nikki Cheng; Shawn Levy; Brian Bierie; Richard M Caprioli; Harold L Moses
Genomic and proteomic analysis of mammary tumors arising in transgenic mice.
Journal of proteome research 2005;4(6):2088-98.
2005: Nikki Cheng; Neil A Bhowmick; Anna Chytil; Agnieszka E Gorksa; Kimberly A Brown; Rebecca Cook; Carlos L Arteaga; Eric G Neilson; Simon W Hayward; Harold L Moses
Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networks.
Oncogene 2005;24(32):5053-68.
2005: Lynda O'Rear; Lara Longobardi; Monica Torello; B K Law; Harold L Moses; Francesco Chiarelli; Anna Spagnoli
Signaling cross-talk between IGF-binding protein-3 and transforming growth factor-(beta) in mesenchymal chondroprogenitor cell growth.
Journal of molecular endocrinology 2005;34(3):723-37.
2005: Anna L Means; Anna Chytil; Harold L Moses; Robert J Coffey; Christopher V E Wright; Makoto M Taketo; William M Grady
Keratin 19 gene drives Cre recombinase expression throughout the early postimplantation mouse embryo.
Genesis (New York, N.Y. : 2000) 2005;42(1):23-7.
2005: Judith Romero-Gallo; Elif G Sozmen; Anna Chytil; William E Russell; Robert Whitehead; W Tony Parks; Matthew S Holdren; Momoko F Her; Shiva Gautam; Mark Magnuson; Harold L Moses; William M Grady
Inactivation of TGF-beta signaling in hepatocytes results in an increased proliferative response after partial hepatectomy.
Oncogene 2005;24(18):3028-41.
2005: Jay S Desgrosellier; Nathan A Mundell; Maureen A McDonnell; Harold L Moses; Joey V Barnett
Activin receptor-like kinase 2 and Smad6 regulate epithelial-mesenchymal transformation during cardiac valve formation.
Developmental biology 2005;280(1):201-10.
2005: Elizabeth Forrester; Anna Chytil; Brian Bierie; Mary E Aakre; Agnieszka E Gorska; Ali-Reza Sharif-Afshar; William J Muller; Harold L Moses
Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis.
Cancer research 2005;65(6):2296-302.
2005: Neil A Bhowmick; Harold L Moses
Tumor-stroma interactions.
Current opinion in genetics & development 2005;15(1):97-101.
2004: Michael O Baffi; Erin Slattery; Philip Sohn; Harold L Moses; Anna Chytil; Rosa Serra
Conditional deletion of the TGF-beta type II receptor in Col2a expressing cells results in defects in the axial skeleton without alterations in chondrocyte differentiation or embryonic development of long bones.
Developmental biology 2004;276(1):124-42.
2004: Neil A Bhowmick; Eric G Neilson; Harold L Moses
Stromal fibroblasts in cancer initiation and progression.
Nature 2004;432(7015):332-7.
2004: Lu Xie; Brian K Law; Anna Chytil; Kimberly A Brown; Mary E Aakre; Harold L Moses
Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro.
Neoplasia (New York, N.Y.) 2004;6(5):603-10.
2004: Swati Biswas; Anna Chytil; Kay Washington; Judith Romero-Gallo; Agnieszka E Gorska; Pamela S Wirth; Shiva Gautam; Harold L Moses; William M Grady
Transforming growth factor beta receptor type II inactivation promotes the establishment and progression of colon cancer.
Cancer research 2004;64(14):4687-92.
2004: Jörn-Hendrik Weitkamp; Michelle Donna Spring; Terrance Brogan; Harold L Moses; Karen C Bloch; Peter F Wright
Influenza A virus-associated acute necrotizing encephalopathy in the United States.
The Pediatric infectious disease journal 2004;23(3):259-63.
2004: Neil A Bhowmick; Anna Chytil; David Plieth; Agnieszka E Gorska; Nancy Dumont; Scott B Shappell; M Kay Washington; Eric G Neilson; Harold L Moses
TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia.
Science (New York, N.Y.) 2004;303(5659):848-51.
2004: David Beebe; Claudia Garcia; Xiaohui Wang; Ramya Rajagopal; Mary Feldmeier; Ji-Young Kim; Anna Chytil; Harold L Moses; Ruth Ashery-Padan; Michael Rauchman
Contributions by members of the TGFbeta superfamily to lens development.
The International journal of developmental biology 2004;48(8-9):845-56.
2004: Kimberly A Brown; Mary E Aakre; Agnieszka E Gorska; James O Price; Sakina E Eltom; Jennifer A Pietenpol; Harold L Moses
Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro.
Breast cancer research : BCR 2004;6(3):R215-31.
2003: Neil A Bhowmick; Mayshan Ghiassi; Mary E Aakre; Kimberly Brown; Vikas Singh; Harold L Moses
TGF-beta-induced RhoA and p160ROCK activation is involved in the inhibition of Cdc25A with resultant cell-cycle arrest.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(26):15548-53.
2003: Rebecca Cook; Yasuhiro Koh; L Renee Roebuck; Melinda E Sanders; Dana M Brantley-Sieders; Agnieszka E Gorska; Harold L Moses; Carlos L Arteaga
Increased malignancy of Neu-induced mammary tumors overexpressing active transforming growth factor beta1.
Molecular and cellular biology 2003;23(23):8691-703.
2003: Yoshihiro Ito; Jae Yong Yeo; Anna Chytil; Jun Han; Pablo Bringas; Akira Nakajima; Charles F Shuler; Harold L Moses; Yang Chai
Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects.
Development (Cambridge, England) 2003;130(21):5269-80.
2003: Agnieszka E Gorska; Roy A Jensen; Yu Shyr; Mary E Aakre; Neil A Bhowmick; Harold L Moses
Transgenic mice expressing a dominant-negative mutant type II transforming growth factor-beta receptor exhibit impaired mammary development and enhanced mammary tumor formation.
The American journal of pathology 2003;163(4):1539-49.
2003: William H Tu; Tania Z Thomas; Naoya Masumori; Neil A Bhowmick; Agnieszka E Gorska; Yu Shyr; Susan Kasper; Tom Case; Richard L Roberts; Scott B Shappell; Harold L Moses; Robert J Matusik
The loss of TGF-beta signaling promotes prostate cancer metastasis.
Neoplasia (New York, N.Y.) 2003;5(3):267-77.
2003: Lu Xie; Brian K Law; Mary E Aakre; Mary Edgerton; Yu Shyr; Neil A Bhowmick; Harold L Moses
Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line.
Breast cancer research : BCR 2003;5(6):R187-98.
2002: Brian K Law; Anna Chytil; Nancy Dumont; Elizabeth G Hamilton; Mary Waltner-Law; Mary E Aakre; Cassondra D Covington; Harold L Moses
Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells.
Molecular and cellular biology 2002;22(23):8184-98.
2002: Keith B Glaser; Junling Li; Mary E Aakre; Douglas W Morgan; George S Sheppard; Kent D Stewart; Jennifer Pollock; Paul Lee; Chad Z O'Connor; Steven N Anderson; Donna J Mussatto; Craig W Wegner; Harold L Moses
Transforming growth factor beta mimetics: discovery of 7-[4-(4-cyanophenyl)phenoxy]-heptanohydroxamic acid, a biaryl hydroxamate inhibitor of histone deacetylase.
Molecular cancer therapeutics 2002;1(10):759-68.
2002: Anna Chytil; Mark Magnuson; Christopher V E Wright; Harold L Moses
Conditional inactivation of the TGF-beta type II receptor using Cre:Lox.
Genesis (New York, N.Y. : 2000) 2002;32(2):73-5.
2001: Neil A Bhowmick; Roy Zent; Mayshan Ghiassi; M McDonnell; Harold L Moses
Integrin beta 1 signaling is necessary for transforming growth factor-beta activation of p38MAPK and epithelial plasticity.
The Journal of biological chemistry 2001;276(50):46707-13.
2001: A D Bragg; Harold L Moses; Rosa Serra
Signaling to the epithelium is not sufficient to mediate all of the effects of transforming growth factor beta and bone morphogenetic protein 4 on murine embryonic lung development.
Mechanisms of development 2001;109(1):13-26.
2001: Daniel J Satterwhite; Raymond White; Mary E Aakre; Harold L Moses
TGF-beta1 regulates the expression of multiple max-interacting transcription factors in Balb/MK cells: implications for understanding the mechanism of action of TGF-beta1.
Pediatric research 2001;50(1):67-75.
2001: Maureen A McDonnell; Brian K Law; R Serra; Harold L Moses
Antagonistic effects of TGFbeta1 and BMP-6 on skin keratinocyte differentiation.
Experimental cell research 2001;263(2):265-73.
2001: Neil A Bhowmick; Mayshan Ghiassi; Andrei V Bakin; Mary E Aakre; Christopher A Lundquist; Michael Eugene Engel; Carlos L Arteaga; Harold L Moses
Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism.
Molecular biology of the cell 2001;12(1):27-36.
2001: A J Entingh; Brian K Law; Harold L Moses
Induction of the C/EBP homologous protein (CHOP) by amino acid deprivation requires insulin-like growth factor I, phosphatidylinositol 3-kinase, and mammalian target of rapamycin signaling.
Endocrinology 2001;142(1):221-8.
2000: Pran K Datta; M C Blake; Harold L Moses
Regulation of plasminogen activator inhibitor-1 expression by transforming growth factor-beta -induced physical and functional interactions between smads and Sp1.
The Journal of biological chemistry 2000;275(51):40014-9.
2000: Brian K Law; Mary Waltner-Law; A J Entingh; Anna Chytil; Mary E Aakre; Peter Nørgaard; Harold L Moses
Salicylate-induced growth arrest is associated with inhibition of p70s6k and down-regulation of c-myc, cyclin D1, cyclin A, and proliferating cell nuclear antigen.
The Journal of biological chemistry 2000;275(49):38261-7.
2000: Andrei V Bakin; A K Tomlinson; Neil A Bhowmick; Harold L Moses; Carlos L Arteaga
Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.
The Journal of biological chemistry 2000;275(47):36803-10.
2000: Pran K Datta; Harold L Moses
STRAP and Smad7 synergize in the inhibition of transforming growth factor beta signaling.
Molecular and cellular biology 2000;20(9):3157-67.
1999: Michael Eugene Engel; Maureen A McDonnell; Brian K Law; Harold L Moses
Interdependent SMAD and JNK signaling in transforming growth factor-beta-mediated transcription.
The Journal of biological chemistry 1999;274(52):37413-20.
1999: D Saha; Pran K Datta; Hongmiao Sheng; Jason D Morrow; M Wada; Harold L Moses; R Daniel Beauchamp
Synergistic induction of cyclooxygenase-2 by transforming growth factor-beta1 and epidermal growth factor inhibits apoptosis in epithelial cells.
Neoplasia (New York, N.Y.) 1999;1(6):508-17.
1999: H Joseph; Agnieszka E Gorska; Philip Sohn; Harold L Moses; Rosa Serra
Overexpression of a kinase-deficient transforming growth factor-beta type II receptor in mouse mammary stroma results in increased epithelial branching.
Molecular biology of the cell 1999;10(4):1221-34.
1999: S Hougaard; Peter Nørgaard; N Abrahamsen; Harold L Moses; Mogens Spang-Thomsen; Hans Skovgaard Poulsen
Inactivation of the transforming growth factor beta type II receptor in human small cell lung cancer cell lines.
British journal of cancer 1999;79(7-8):1005-11.
1999: Brian K Law; Peter Nørgaard; Luigi Gnudi; Barbara B Kahn; H S Poulson; Harold L Moses
Inhibition of DNA synthesis by a farnesyltransferase inhibitor involves inhibition of the p70(s6k) pathway.
The Journal of biological chemistry 1999;274(8):4743-8.
1999: Peter Nørgaard; Brian K Law; H S Plovisson; Harold L Moses
Farnesyltransferase inhibitor-induced regression of mammary tumors in TGF alpha and TGF alpha/neu transgenic mice correlates with inhibition of map kinase and p70s6 kinase phosphorylation.
Annals of the New York Academy of Sciences 1999;886():265-8.
1999: Peter Nørgaard; Brian Law; H Joseph; D L Page; Yu Shyr; Deborah J Mays; Jennifer A Pietenpol; Nancy E Kohl; Allen Oliff; Robert J Coffey; Hans Skovgaard Poulsen; Harold L Moses
Treatment with farnesyl-protein transferase inhibitor induces regression of mammary tumors in transforming growth factor (TGF) alpha and TGF alpha/neu transgenic mice by inhibition of mitogenic activity and induction of apoptosis.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(1):35-42.
1998: Pran K Datta; Anna Chytil; Agnieszka E Gorska; Harold L Moses
Identification of STRAP, a novel WD domain protein in transforming growth factor-beta signaling.
The Journal of biological chemistry 1998;273(52):34671-4.
1998: M G Alexandrow; Harold L Moses
c-myc-enhanced S phase entry in keratinocytes is associated with positive and negative effects on cyclin-dependent kinases.
Journal of cellular biochemistry 1998;70(4):528-42.
1998: Michael Eugene Engel; Pran K Datta; Harold L Moses
RhoB is stabilized by transforming growth factor beta and antagonizes transcriptional activation.
The Journal of biological chemistry 1998;273(16):9921-6.
1998: Agnieszka E Gorska; H Joseph; Rik Derynck; Harold L Moses; Rosa Serra
Dominant-negative interference of the transforming growth factor beta type II receptor in mammary gland epithelium results in alveolar hyperplasia and differentiation in virgin mice.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(3):229-38.
1998: Michael Eugene Engel; Pran K Datta; Harold L Moses
Signal transduction by transforming growth factor-beta: a cooperative paradigm with extensive negative regulation.
Journal of cellular biochemistry. Supplement 1998;30-31():111-22.
1997: Rosa Serra; M Johnson; Ellen H Filvaroff; J LaBorde; D M Sheehan; Rik Derynck; Harold L Moses
Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis.
The Journal of cell biology 1997;139(2):541-52.
1997: M G Alexandrow; Harold L Moses
Kips off to Myc: implications for TGF beta signaling.
Journal of cellular biochemistry 1997;66(4):427-32.
1995: M S Steiner; C T Anthony; J Metts; Harold L Moses
Prostate cancer cells lose their sensitivity to TGFβI growth inhibition with tumor progression.
Urologic oncology 1995;1(6):252-62.
1995: M G Alexandrow; Harold L Moses
Transforming growth factor beta 1 inhibits mouse keratinocytes late in G1 independent of effects on gene transcription.
Cancer research 1995;55(17):3928-32.
1995: R Serra; Harold L Moses
pRb is necessary for inhibition of N-myc expression by TGF-beta 1 in embryonic lung organ cultures.
Development (Cambridge, England) 1995;121(9):3057-66.
1995: D F Pierce; Agnieszka E Gorska; A Chytil; Katherine S Meise; David L Page; Robert J Coffey; Harold L Moses
Mammary tumor suppression by transforming growth factor beta 1 transgene expression.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(10):4254-8.
1995: M G Alexandrow; M Kawabata; M Aakre; Harold L Moses
Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(8):3239-43.
1995: M Kawabata; A Chytil; Harold L Moses
Cloning of a novel type II serine/threonine kinase receptor through interaction with the type I transforming growth factor-beta receptor.
The Journal of biological chemistry 1995;270(10):5625-30.
1995: L Dagnino; Liang Zhu; K L Skorecki; Harold L Moses
E2F-independent transcriptional repression by p107, a member of the retinoblastoma family of proteins.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1995;6(2):191-8.
1994: D J Satterwhite; M E Aakre; Agnieszka E Gorska; Harold L Moses
Inhibition of cell growth by TGF beta 1 is associated with inhibition of B-myb and cyclin A in both BALB/MK and Mv1Lu cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(8):789-99.
1994: R Serra; R W Pelton; Harold L Moses
TGF beta 1 inhibits branching morphogenesis and N-myc expression in lung bud organ cultures.
Development (Cambridge, England) 1994;120(8):2153-61.
1994: Harold L Moses; Carlos L Arteaga; M G Alexandrow; L Dagnino; M Kawabata; D F Pierce; R Serra
TGF beta regulation of cell proliferation.
Princess Takamatsu symposia 1994;24():250-63.
1993: D F Pierce; M D Johnson; Y Matsui; S D Robinson; L I Gold; A F Purchio; Charles W Daniel; Brigid L M Hogan; Harold L Moses
Inhibition of mammary duct development but not alveolar outgrowth during pregnancy in transgenic mice expressing active TGF-beta 1.
Genes & development 1993;7(12A):2308-17.
1993: M D Johnson; Mark T. Jennings; L I Gold; Harold L Moses
Transforming growth factor-beta in neural embryogenesis and neoplasia.
Human pathology 1993;24(5):457-62.
1993: Carlos L Arteaga; T Carty-Dugger; Harold L Moses; S D Hurd; Jennifer A Pietenpol
Transforming growth factor beta 1 can induce estrogen-independent tumorigenicity of human breast cancer cells in athymic mice.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993;4(3):193-201.
1993: L Dagnino; Jennifer A Pietenpol; E Y Yang; Harold L Moses
Transforming growth factor regulation of keratinocyte growth.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1993;128():15-29.
1992: M D Johnson; L I Gold; Harold L Moses
Evidence for transforming growth factor-beta expression in human leptomeningeal cells and transforming growth factor-beta-like activity in human cerebrospinal fluid.
Laboratory investigation; a journal of technical methods and pathology 1992;67(3):360-8.
1992: Harold L Moses
TGF-beta regulation of epithelial cell proliferation.
Molecular reproduction and development 1992;32(2):179-84.
1992: R Daniel Beauchamp; H M Sheng; C C Bascom; D A Miller; R M Lyons; G Torre-Amione; Harold L Moses
Phenotypic alterations in fibroblasts and fibrosarcoma cells that overexpress latent transforming growth factor-beta 1.
Endocrinology 1992;130(5):2476-86.
1991: R W Pelton; M D Johnson; EA Perkett; L I Gold; Harold L Moses
Expression of transforming growth factor-beta 1, -beta 2, and -beta 3 mRNA and protein in the murine lung.
American journal of respiratory cell and molecular biology 1991;5(6):522-30.
1991: John A Barnard; W H Polk; Harold L Moses; Robert J Coffey
Production of transforming growth factor-alpha by normal rat small intestine.
The American journal of physiology 1991;261(6 Pt 1):C994-1000.
1991: R M Lyons; D A Miller; J L Graycar; Harold L Moses; Rik Derynck
Differential binding of transforming growth factor-beta 1, -beta 2, and -beta 3 by fibroblasts and epithelial cells measured by affinity cross-linking of cell surface receptors.
Molecular endocrinology (Baltimore, Md.) 1991;5(12):1887-96.
1991: Jennifer A Pietenpol; K Münger; Peter M Howley; R W Stein; Harold L Moses
Factor-binding element in the human c-myc promoter involved in transcriptional regulation by transforming growth factor beta 1 and by the retinoblastoma gene product.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(22):10227-31.
1991: R W Pelton; B Saxena; M Jones; Harold L Moses; L I Gold
Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development.
The Journal of cell biology 1991;115(4):1091-105.
1991: Herbert S Schwartz; Merlin G Butler; R B Jenkins; D A Miller; Harold L Moses
Telomeric associations and consistent growth factor overexpression detected in giant cell tumor of bone.
Cancer genetics and cytogenetics 1991;56(2):263-76.
1991: R Daniel Beauchamp; Robert J Coffey; R M Lyons; EA Perkett; Courtney M Townsend; Harold L Moses
Human carcinoid cell production of paracrine growth factors that can stimulate fibroblast and endothelial cell growth.
Cancer research 1991;51(19):5253-60.
1991: Mark T. Jennings; Robert J Maciunas; R Carver; C C Bascom; P Juneau; K Misulis; Harold L Moses
TGF beta 1 and TGF beta 2 are potential growth regulators for low-grade and malignant gliomas in vitro: evidence in support of an autocrine hypothesis.
International journal of cancer. Journal international du cancer 1991;49(1):129-39.
1991: Harold L Moses; E Y Yang; Jennifer A Pietenpol
Regulation of epithelial proliferation by TGF-beta.
Ciba Foundation symposium 1991;157():66-74; discussion 75-80.
1991: Harold L Moses; Jennifer A Pietenpol; K Münger; C S Murphy; E Y Yang
TGF beta regulation of epithelial cell proliferation: role of tumor suppressor genes.
Princess Takamatsu symposia 1991;22():183-95.
1991: C S Murphy; Jennifer A Pietenpol; K Münger; Peter M Howley; Harold L Moses
c-myc and pRB: role in TGF-beta 1 inhibition of keratinocyte proliferation.
Cold Spring Harbor symposia on quantitative biology 1991;56():129-35.
1990: R W Pelton; Harold L Moses
The beta-type transforming growth factor. Mediators of cell regulation in the lung.
The American review of respiratory disease 1990;142(6 Pt 2):S31-5.
1990: R A Fava; T T Casey; Josiah N Wilcox; R W Pelton; Harold L Moses; Lillian B Nanney
Synthesis of transforming growth factor-beta 1 by megakaryocytes and its localization to megakaryocyte and platelet alpha-granules.
Blood 1990;76(10):1946-55.
1990: EA Perkett; R M Lyons; Harold L Moses; Kenneth L Brigham; Barbara Meyrick
Transforming growth factor-beta activity in sheep lung lymph during the development of pulmonary hypertension.
The Journal of clinical investigation 1990;86(5):1459-64.
1990: Harold L Moses; E Y Yang; Jennifer A Pietenpol
TGF-beta stimulation and inhibition of cell proliferation: new mechanistic insights.
Cell 1990;63(2):245-7.
1990: R W Pelton; M E Dickinson; Harold L Moses; Brigid L M Hogan
In situ hybridization analysis of TGF beta 3 RNA expression during mouse development: comparative studies with TGF beta 1 and beta 2.
Development (Cambridge, England) 1990;110(2):609-20.
1990: R W Pelton; Brigid L M Hogan; D A Miller; Harold L Moses
Differential expression of genes encoding TGFs beta 1, beta 2, and beta 3 during murine palate formation.
Developmental biology 1990;141(2):456-60.
1990: Carlos L Arteaga; Robert J Coffey; Teresa C Dugger; C M McCutchen; Harold L Moses; R M Lyons
Growth stimulation of human breast cancer cells with anti-transforming growth factor beta antibodies: evidence for negative autocrine regulation by transforming growth factor beta.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1990;1(8):367-74.
1990: E Y Yang; Harold L Moses
Transforming growth factor beta 1-induced changes in cell migration, proliferation, and angiogenesis in the chicken chorioallantoic membrane.
The Journal of cell biology 1990;111(2):731-41.
1990: R Daniel Beauchamp; R M Lyons; E Y Yang; Robert J Coffey; Harold L Moses
Expression of and response to growth regulatory peptides by two human pancreatic carcinoma cell lines.
Pancreas 1990;5(4):369-80.
1990: John A Barnard; R M Lyons; Harold L Moses
The cell biology of transforming growth factor beta.
Biochimica et biophysica acta 1990;1032(1):79-87.
1990: Jennifer A Pietenpol; R W Stein; Elizabeth Moran; Peter Yaciuk; R Schlegel; R M Lyons; Mark Pittelkow; K Münger; Peter M Howley; Harold L Moses
TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains.
Cell 1990;61(5):777-85.
1990: Jennifer A Pietenpol; Jeffrey T Holt; R W Stein; Harold L Moses
Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(10):3758-62.
1990: N J Sipes; D A Miller; C C Bascom; J K Winkler; Lynn M Matrisian; Harold L Moses
Altered regulation of protein disulfide isomerase in cells resistant to the growth-inhibitory effects of transforming growth factor beta 1.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1990;1(5):241-6.
1990: G Torre-Amione; R Daniel Beauchamp; H Koeppen; Ben Ho Park; Hans Schreiber; Harold L Moses; D A Rowley
A highly immunogenic tumor transfected with a murine transforming growth factor type beta 1 cDNA escapes immune surveillance.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(4):1486-90.
1990: D A Miller; R W Pelton; Rik Derynck; Harold L Moses
Transforming growth factor-beta. A family of growth regulatory peptides.
Annals of the New York Academy of Sciences 1990;593():208-17.
1990: N J Sipes; R M Lyons; Harold L Moses
Isolation and characterization of Kirsten murine sarcoma virus-transformed mouse keratinocytes resistant to transforming growth factor beta.
Molecular carcinogenesis 1990;3(1):12-9.
1989: J L Graycar; D A Miller; B A Arrick; R M Lyons; Harold L Moses; Rik Derynck
Human transforming growth factor-beta 3: recombinant expression, purification, and biological activities in comparison with transforming growth factors-beta 1 and -beta 2.
Molecular endocrinology (Baltimore, Md.) 1989;3(12):1977-86.
1989: D A Miller; A Lee; Y Matsui; E Y Chen; Harold L Moses; Rik Derynck
Complementary DNA cloning of the murine transforming growth factor-beta 3 (TGF beta 3) precursor and the comparative expression of TGF beta 3 and TGF beta 1 messenger RNA in murine embryos and adult tissues.
Molecular endocrinology (Baltimore, Md.) 1989;3(12):1926-34.
1989: C C Bascom; J R Wolfshohl; Robert J Coffey; L Madisen; N R Webb; A R Purchio; Rik Derynck; Harold L Moses
Complex regulation of transforming growth factor beta 1, beta 2, and beta 3 mRNA expression in mouse fibroblasts and keratinocytes by transforming growth factors beta 1 and beta 2.
Molecular and cellular biology 1989;9(12):5508-15.
1989: D A Miller; A Lee; R W Pelton; E Y Chen; Harold L Moses; Rik Derynck
Murine transforming growth factor-beta 2 cDNA sequence and expression in adult tissues and embryos.
Molecular endocrinology (Baltimore, Md.) 1989;3(7):1108-14.
1989: Michael Skinner; Harold L Moses
Transforming growth factor beta gene expression and action in the seminiferous tubule: peritubular cell-Sertoli cell interactions.
Molecular endocrinology (Baltimore, Md.) 1989;3(4):625-34.
1989: John A Barnard; R Daniel Beauchamp; Robert J Coffey; Harold L Moses
Regulation of intestinal epithelial cell growth by transforming growth factor type beta.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(5):1578-82.
1989: C C Bascom; N J Sipes; Robert J Coffey; Harold L Moses
Regulation of epithelial cell proliferation by transforming growth factors.
Journal of cellular biochemistry 1989;39(1):25-32.
1988: John A Barnard; C C Bascom; R M Lyons; N J Sipes; Harold L Moses
Transforming growth factor beta in the control of epidermal proliferation.
The American journal of the medical sciences 1988;296(3):159-63.
1988: Robert J Coffey; C C Bascom; N J Sipes; Ramona Graves-Deal; Bernard E Weissman; Harold L Moses
Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor beta.
Molecular and cellular biology 1988;8(8):3088-93.
1988: R M Lyons; Jorma Keski-Oja; Harold L Moses
Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium.
The Journal of cell biology 1988;106(5):1659-65.
1988: Robert J Coffey; N J Sipes; C C Bascom; Ramona Graves-Deal; C Y Pennington; Bernard E Weissman; Harold L Moses
Growth modulation of mouse keratinocytes by transforming growth factors.
Cancer research 1988;48(6):1596-602.
1988: Jorma Keski-Oja; Rajendra Raghow; M Sawdey; D J Loskutoff; A E Postlethwaite; A H Kang; Harold L Moses
Regulation of mRNAs for type-1 plasminogen activator inhibitor, fibronectin, and type I procollagen by transforming growth factor-beta. Divergent responses in lung fibroblasts and carcinoma cells.
The Journal of biological chemistry 1988;263(7):3111-5.
1988: Jorma Keski-Oja; F Blasi; Edward B Leof; Harold L Moses
Regulation of the synthesis and activity of urokinase plasminogen activator in A549 human lung carcinoma cells by transforming growth factor-beta.
The Journal of cell biology 1988;106(2):451-9.
1988: Jorma Keski-Oja; A E Postlethwaite; Harold L Moses
Transforming growth factors in the regulation of malignant cell growth and invasion.
Cancer investigation 1988;6(6):705-24.
1987: Jorma Keski-Oja; R M Lyons; Harold L Moses
Immunodetection and modulation of cellular growth with antibodies against native transforming growth factor-beta 1.
Cancer research 1987;47(24 Pt 1):6451-8.
1987: Jorma Keski-Oja; Edward B Leof; R M Lyons; Robert J Coffey; Harold L Moses
Transforming growth factors and control of neoplastic cell growth.
Journal of cellular biochemistry 1987;33(2):95-107.
1987: Harold L Moses; Robert J Coffey; Edward B Leof; R M Lyons; Jorma Keski-Oja
Transforming growth factor beta regulation of cell proliferation.
Journal of cellular physiology. Supplement 1987;Suppl 5():1-7.