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Jackob Moskovitz

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TOP 3
Jackob Moskovitz
Antibodies against methionine sulfoxide of proteins.
Jade M Franklin; Gonzalo A Carrasco; Jackob Moskovitz
Induction of methionine sulfoxide reductase activity by pergolide, pergolide sulfoxide, and S-adenosyl-methionine in neuronal cells.
Jackob Moskovitz; Mark Band; Alvaro Hernandez; Assaf Malik; Aaron Avivi
Methionine sulfoxide reductases and methionine sulfoxide in the subterranean mole rat (Spalax): characterization of expression under various oxygen conditions.

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All Publications

2013: Jackob Moskovitz
Antibodies against methionine sulfoxide of proteins.
Free radical biology & medicine 2013;56():234-5.
2013: Jade M Franklin; Gonzalo A Carrasco; Jackob Moskovitz
Induction of methionine sulfoxide reductase activity by pergolide, pergolide sulfoxide, and S-adenosyl-methionine in neuronal cells.
Neuroscience letters 2013;533():86-9.
2012: Jackob Moskovitz; Mark Band; Alvaro Hernandez; Assaf Malik; Aaron Avivi
Methionine sulfoxide reductases and methionine sulfoxide in the subterranean mole rat (Spalax): characterization of expression under various oxygen conditions.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2012;161(4):406-14.
2012: John M Ringman; Giovanni Coppola; Jeffrey L Cummings; David Elashoff; Andrew T Fithian; Karen H Gylys; Jackob Moskovitz; Domenico Pratico'; Gal Bitan
Plasma methionine sulfoxide in persons with familial Alzheimer's disease mutations.
Dementia and geriatric cognitive disorders 2012;33(4):219-25.
2012: Lindsay B Henderson; Michael R Knowles; Jackob Moskovitz; Kathleen M Naughton; Rhonda G Pace; SCOTT BLACKMAN; Vishal K Doshi; Mitchell L Drumm; Peter R Durie; Garry R Cutting
Variation in MSRA modifies risk of neonatal intestinal obstruction in cystic fibrosis.
PLoS genetics 2012;8(3):e1002580.
2011: Jackob Moskovitz; Derek B Oien; Aida Attar; Jane Hayes; Tingyu Liu; Dahabada H J Lopes; Panchanan Maiti; Shivina Mittal; Gal Bitan
Induction of methionine-sulfoxide reductases protects neurons from amyloid β-protein insults in vitro and in vivo.
Biochemistry 2011;50(49):10687-97.
2011: A N Ortiz; Derek B Oien; Jackob Moskovitz; M A Johnson
Quantification of reserve pool dopamine in methionine sulfoxide reductase A null mice.
Neuroscience 2011;177():223-9.
2011: Derek B Oien; Gonzalo A Carrasco; Jackob Moskovitz
Decreased Phosphorylation and Increased Methionine Oxidation of α-Synuclein in the Methionine Sulfoxide Reductase A Knockout Mouse.
Journal of amino acids 2011;2011():721094.
2010: Derek B Oien; Andrea N Ortiz; Alexander G Rittel; Rick T Dobrowsky; Michael A Johnson; Beth Levant; Stephen C Fowler; Jackob Moskovitz
Dopamine D(2) receptor function is compromised in the brain of the methionine sulfoxide reductase A knockout mouse.
Journal of neurochemistry 2010;114(1):51-61.
2010: Jackob Moskovitz; Derek B Oien
Protein carbonyl and the methionine sulfoxide reductase system.
Antioxidants & redox signaling 2010;12(3):405-15.
2010: Tamar Canello; Kati Frid; Ruth Gabizon; Silvia Lisa; Assaf Friedler; Jackob Moskovitz; María Gasset; Ruth Gabizon
Oxidation of Helix-3 methionines precedes the formation of PK resistant PrP.
PLoS pathogens 2010;6(7):e1000977.
2010: Derek B Oien; Gregory L Osterhaus; Brandi L Lundquist; Stephen C Fowler; Jackob Moskovitz
Caloric restriction alleviates abnormal locomotor activity and dopamine levels in the brain of the methionine sulfoxide reductase A knockout mouse.
Neuroscience letters 2010;468(1):38-41.
2009: Tolulope T Oke; Jackob Moskovitz; David L Williams
Characterization of the methionine sulfoxide reductases of Schistosoma mansoni.
The Journal of parasitology 2009;95(6):1421-8.
2009: Derek B Oien; Heather E Shinogle; David S Moore; Jackob Moskovitz
Clearance and phosphorylation of alpha-synuclein are inhibited in methionine sulfoxide reductase a null yeast cells.
Journal of molecular neuroscience : MN 2009;39(3):323-32.
2009: Derek B Oien; Tamar Canello; Ruth Gabizon; Maria Gasset; Brandi L Lundquist; Jeff M Burns; Jackob Moskovitz
Detection of oxidized methionine in selected proteins, cellular extracts and blood serums by novel anti-methionine sulfoxide antibodies.
Archives of biochemistry and biophysics 2009;485(1):35-40.
2009: Vladimir Vinokur; Leonid Grinberg; Eduard Berenshtein; Menachem Gross; Jackob Moskovitz; Abraham Z Reznick; Mordechai Chevion; Ron Eliashar
Methionine-centered redox cycle in organs of the aero-digestive tract of young and old rats.
Biogerontology 2009;10(1):43-52.
2009: Derek B Oien; Jackob Moskovitz
Selenium and the methionine sulfoxide reductase system.
Molecules (Basel, Switzerland) 2009;14(7):2337-44.
2008: Derek B Oien; Greg L Osterhaus; Shaheen A Latif; Jonathan W Pinkston; Jenny Fulks; Michael Johnson; Stephen C Fowler; Jackob Moskovitz
MsrA knockout mouse exhibits abnormal behavior and brain dopamine levels.
Free radical biology & medicine 2008;45(2):193-200.
2008: Derek B Oien; Jackob Moskovitz
Substrates of the methionine sulfoxide reductase system and their physiological relevance.
Current topics in developmental biology 2008;80():93-133.
2007: Ranu Pal; Derek B Oien; Fatma Y Ersen; Jackob Moskovitz
Elevated levels of brain-pathologies associated with neurodegenerative diseases in the methionine sulfoxide reductase A knockout mouse.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2007;180(4):765-74.
2007: Eric O Uthus; Jackob Moskovitz
Specific activity of methionine sulfoxide reductase in CD-1 mice is significantly affected by dietary selenium but not zinc.
Biological trace element research 2007;115(3):265-76.
2007: Jackob Moskovitz
Prolonged selenium-deficient diet in MsrA knockout mice causes enhanced oxidative modification to proteins and affects the levels of antioxidant enzymes in a tissue-specific manner.
Free radical research 2007;41(2):162-71.
2007: Derek B Oien; Jackob Moskovitz
Ablation of the mammalian methionine sulfoxide reductase A affects the expression level of cysteine deoxygenase.
Biochemical and biophysical research communications 2007;352(2):556-9.
2007: Derek B Oien; Jackob Moskovitz
Protein-carbonyl accumulation in the non-replicative senescence of the methionine sulfoxide reductase A (msrA) knockout yeast strain.
Amino acids 2007;32(4):603-6.
2006: Robyn G Midwinter; Fook-Choe Cheah; Jackob Moskovitz; Margret C M Vissers; Christine C Winterbourn
IkappaB is a sensitive target for oxidation by cell-permeable chloramines: inhibition of NF-kappaB activity by glycine chloramine through methionine oxidation.
The Biochemical journal 2006;396(1):71-8.
2006: Ingeborg Hanbauer; Jackob Moskovitz
The yeast cytosolic thioredoxins are involved in the regulation of methionine sulfoxide reductase A.
Free radical biology & medicine 2006;40(8):1391-6.
2005: Jackob Moskovitz
Methionine sulfoxide reductases: ubiquitous enzymes involved in antioxidant defense, protein regulation, and prevention of aging-associated diseases.
Biochimica et biophysica acta 2005;1703(2):213-9.
2005: Jackob Moskovitz
Roles of methionine suldfoxide reductases in antioxidant defense, protein regulation and survival.
Current pharmaceutical design 2005;11(11):1451-7.
2004: WM Williams; Earl R Stadtman; Jackob Moskovitz
Ageing and exposure to oxidative stress in vivo differentially affect cellular levels of PrP in mouse cerebral microvessels and brain parenchyma.
Neuropathology and applied neurobiology 2004;30(2):161-8.
2003: Ronit Rotem; Orit Fingrut; Jackob Moskovitz; Eliezer Flescher
The anticancer agent methyl jasmonate induces activation of stress-regulated c-Jun N-terminal kinase and p38 protein kinase in human lymphoid cells.
Leukemia 2003;17(11):2230-4.
2003: Earl R Stadtman; Jackob Moskovitz; Rodney L Levine
Oxidation of methionine residues of proteins: biological consequences.
Antioxidants & redox signaling 2003;5(5):577-82.
2003: Vineet K Singh; Jackob Moskovitz
Multiple methionine sulfoxide reductase genes in Staphylococcus aureus: expression of activity and roles in tolerance of oxidative stress.
Microbiology (Reading, England) 2003;149(Pt 10):2739-47.
2003: Ingeborg Hanbauer; Emily Boja; Jackob Moskovitz
A homologue of elongation factor 1 gamma regulates methionine sulfoxide reductase A gene expression in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(14):8199-204.
2003: Jackob Moskovitz; Earl R Stadtman
Selenium-deficient diet enhances protein oxidation and affects methionine sulfoxide reductase (MsrB) protein level in certain mouse tissues.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(13):7486-90.
2002: Keith P Mintz; Jackob Moskovitz; Hui Wu; Paula M Fives-Taylor
Peptide methionine sulfoxide reductase (MsrA) is not a major virulence determinant for the oral pathogen Actinobacillus actinomycetemcomitans.
Microbiology (Reading, England) 2002;148(Pt 11):3695-703.
2002: Shoshana Bar-Noy; Jackob Moskovitz
Mouse methionine sulfoxide reductase B: effect of selenocysteine incorporation on its activity and expression of the seleno-containing enzyme in bacterial and mammalian cells.
Biochemical and biophysical research communications 2002;297(4):956-61.
2002: Mayumi Mohri; Peter S Reinach; Atsuhiro Kanayama; Makoto Shimizu; Jackob Moskovitz; Tatsuhiro Hisatsune; Yusei Miyamoto
Suppression of the TNFalpha-induced increase in IL-1alpha expression by hypochlorite in human corneal epithelial cells.
Investigative ophthalmology & visual science 2002;43(10):3190-5.
2002: Earl R Stadtman; Jackob Moskovitz; Barbara S Berlett; Rodney L Levine
Cyclic oxidation and reduction of protein methionine residues is an important antioxidant mechanism.
Molecular and cellular biochemistry 2002;234-235(1-2):3-9.
2002: David A Davis; Elizabeth Read-Connole; Kara Pearson; Henry M Fales; Fonda M Newcomb; Jackob Moskovitz; Robert Yarchoan
Oxidative modifications of kynostatin-272, a potent human immunodeficiency virus type 1 protease inhibitor: potential mechanism for altered activity in monocytes/macrophages.
Antimicrobial agents and chemotherapy 2002;46(2):402-8.
2002: Jackob Moskovitz; Moon Bin Yim; P Boon Chock
Free radicals and disease.
Archives of biochemistry and biophysics 2002;397(2):354-9.
2002: Jackob Moskovitz; Vineet K Singh; Jesús R Requena; Brian J Wilkinson; Radheshyam K Jayaswal; Earl R Stadtman
Purification and characterization of methionine sulfoxide reductases from mouse and Staphylococcus aureus and their substrate stereospecificity.
Biochemical and biophysical research communications 2002;290(1):62-5.
2002: David A Davis; Fonda M Newcomb; Jackob Moskovitz; Henry M Fales; Rodney L Levine; Robert Yarchoan
Reversible oxidation of HIV-2 protease.
Methods in enzymology 2002;348():249-59.
2001: Jackob Moskovitz; Shoshana Bar-Noy; WM Williams; Jesús R Requena; Barbara S Berlett; Earl R Stadtman
Methionine sulfoxide reductase (MsrA) is a regulator of antioxidant defense and lifespan in mammals.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(23):12920-5.
2001: Vineet K Singh; Jackob Moskovitz; Brian J Wilkinson; Radheshyam K Jayaswal
Molecular characterization of a chromosomal locus in Staphylococcus aureus that contributes to oxidative defence and is highly induced by the cell-wall-active antibiotic oxacillin.
Microbiology (Reading, England) 2001;147(Pt 11):3037-45.
2000: R L Levine; Jackob Moskovitz; Earl R Stadtman
Oxidation of methionine in proteins: roles in antioxidant defense and cellular regulation.
IUBMB life 2000;50(4-5):301-7.
2000: Jackob Moskovitz; JM Poston; Barbara S Berlett; Neil Nosworthy; Roman H Szczepanowski; Earl R Stadtman
Identification and characterization of a putative active site for peptide methionine sulfoxide reductase (MsrA) and its substrate stereospecificity.
The Journal of biological chemistry 2000;275(19):14167-72.
2000: David A Davis; Fonda M Newcomb; Jackob Moskovitz; Paul T Wingfield; Stephen J Stahl; Joshua Kaufman; Henry M Fales; R L Levine; Robert Yarchoan
HIV-2 protease is inactivated after oxidation at the dimer interface and activity can be partly restored with methionine sulphoxide reductase.
The Biochemical journal 2000;346 Pt 2():305-11.
1999: Rodney L Levine; Barbara S Berlett; Jackob Moskovitz; L Mosoni; Earl R Stadtman
Methionine residues may protect proteins from critical oxidative damage.
Mechanisms of ageing and development 1999;107(3):323-32.
1999: Jackob Moskovitz; Barbara S Berlett; JM Poston; Earl R Stadtman
Methionine sulfoxide reductase in antioxidant defense.
Methods in enzymology 1999;300():239-44.
1998: Jackob Moskovitz; Eliezer Flescher; Barbara S Berlett; J Azare; JM Poston; Earl R Stadtman
Overexpression of peptide-methionine sulfoxide reductase in Saccharomyces cerevisiae and human T cells provides them with high resistance to oxidative stress.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(24):14071-5.
1997: Jackob Moskovitz; Barbara S Berlett; JM Poston; Earl R Stadtman
The yeast peptide-methionine sulfoxide reductase functions as an antioxidant in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(18):9585-9.