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Gabriela Möslein

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Ralph Schneider; Claudia Schneider; Alois Fürst; Matthias Kloor; Gabriela Möslein
Lynch syndrome: clinical, pathological, and genetic insights.
Karin Hardt; Sven Boris Heick; Beate Betz; Timm Goecke; Haniyeh Yazdanparast; Robin Küppers; Kati Servan; Verena Steinke; Nils Rahner; Monika Morak; Elke Holinski-Feder; Christoph Engel; Gabriela Möslein; Hans-Konrad Schackert; Magnus von Knebel Doeberitz; Christian Pox; Johannes H Hegemann; Brigitte Royer-Pokora
Missense variants in hMLH1 identified in patients from the German HNPCC consortium and functional studies.
John Burn; Pamela D Chapman; Julie Coaker; Malcolm G Dunlop; Diana Eccles; Faye Elliott; Anthony Ellis; D Gareth Evans; Riccardo Fodde; Eamonn R Maher; John C Mathers; Gabriela Möslein; Robin K S Phillips; Hans F A Vasen; Lucio Bertario; D Timothy Bishop; Steffen Bülow
A randomized placebo-controlled prevention trial of aspirin and/or resistant starch in young people with familial adenomatous polyposis.

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All Publications

2012: Ralph Schneider; Claudia Schneider; Alois Fürst; Matthias Kloor; Gabriela Möslein
Lynch syndrome: clinical, pathological, and genetic insights.
Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie 2012;397(4):513-25.
2011: Karin Hardt; Sven Boris Heick; Beate Betz; Timm Goecke; Haniyeh Yazdanparast; Robin Küppers; Kati Servan; Verena Steinke; Nils Rahner; Monika Morak; Elke Holinski-Feder; Christoph Engel; Gabriela Möslein; Hans-Konrad Schackert; Magnus von Knebel Doeberitz; Christian Pox; Johannes H Hegemann; Brigitte Royer-Pokora
Missense variants in hMLH1 identified in patients from the German HNPCC consortium and functional studies.
Familial cancer 2011;10(2):273-84.
2011: John Burn; Pamela D Chapman; Julie Coaker; Malcolm G Dunlop; Diana Eccles; Faye Elliott; Anthony Ellis; D Gareth Evans; Riccardo Fodde; Eamonn R Maher; John C Mathers; Gabriela Möslein; Robin K S Phillips; Hans F A Vasen; Lucio Bertario; D Timothy Bishop; Steffen Bülow
A randomized placebo-controlled prevention trial of aspirin and/or resistant starch in young people with familial adenomatous polyposis.
Cancer prevention research (Philadelphia, Pa.) 2011;4(5):655-65.
2011: M R J Kohonen-Corish; Finlay Macrae; Maurizio Genuardi; Stefan Aretz; Bharati Bapat; Inge T Bernstein; John Burn; Richard G H Cotton; Johan T den Dunnen; Thierry Frebourg; Marc S Greenblatt; Robert Hofstra; Elke Holinski-Feder; Ilkka Lappalainen; Annika Lindblom; Donna Maglott; Pål Møller; Hans Morreau; Gabriela Möslein; Rolf Sijmons; Amanda B Spurdle; Sean V Tavtigian; Carli M J Tops; Thomas K Weber; Niels De Wind; Michael O Woods
Deciphering the colon cancer genes--report of the InSiGHT-Human Variome Project Workshop, UNESCO, Paris 2010.
Human mutation 2011;32(4):491-4.
2010: M R J Kohonen-Corish; Jumana Y Al-Aama; Arleen D Auerbach; Myles Axton; Carol Isaacson Barash; Inge Bernstein; Christophe Béroud; John Burn; Fiona Cunningham; Garry R Cutting; Johan T den Dunnen; Marc S Greenblatt; Jim Kaput; Michael Katz; Annika Lindblom; Finlay Macrae; Donna Maglott; Gabriela Möslein; Sue Povey; Raj Ramesar; Sue Richards; Daniela Seminara; María-Jesús Sobrido; Sean V Tavtigian; Graham Taylor; Mauno Vihinen; Ingrid Winship; Richard G H Cotton
How to catch all those mutations--the report of the third Human Variome Project Meeting, UNESCO Paris, May 2010.
Human mutation 2010;31(12):1374-81.
2010: Christoph Engel; Nils Rahner; Karsten Schulmann; Elke Holinski-Feder; Timm O Goecke; Hans K Schackert; Matthias Kloor; Verena Steinke; Holger Vogelsang; Gabriela Möslein; Heike Görgens; Stefan Dechant; Magnus von Knebel Doeberitz; Josef Rüschoff; Nicolaus Friedrichs; Reinhard Büttner; Markus Loeffler; Peter Propping; Wolff Schmiegel
Efficacy of annual colonoscopic surveillance in individuals with hereditary nonpolyposis colorectal cancer.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2010;8(2):174-82.
2010: Beate Betz; Stephan Theiss; Murat Aktas; Carolin Konermann; Timm O Goecke; Gabriela Möslein; Heiner Schaal; Brigitte Royer-Pokora
Comparative in silico analyses and experimental validation of novel splice site and missense mutations in the genes MLH1 and MSH2.
Journal of cancer research and clinical oncology 2010;136(1):123-34.
2008: Richard G H Cotton; Arleen D Auerbach; Myles Axton; Carol Isaacson Barash; Samuel F Berkovic; Anthony J Brookes; John Burn; Garry R Cutting; Johan T den Dunnen; Paul Flicek; Nelson Freimer; Marc S Greenblatt; Heather J Howard; Michael Katz; Finlay A Macrae; Donna Maglott; Gabriela Möslein; Sue Povey; Rajkumar S Ramesar; Carolyn S (Sue) Richards; Daniela Seminara; Timothy D Smith; María-Jesús Sobrido; Jan Helge Solbakk; Rudolph E Tanzi; Sean V Tavtigian; Graham Taylor; Joji Utsunomiya; Michael Watson
GENETICS. The Human Variome Project.
Science (New York, N.Y.) 2008;322(5903):861-2.
2008: A Liljegren; Gail Barker; Faye Elliott; Lucio Bertario; Marie Luise Bisgaard; Diana Eccles; Gareth Evans; Finlay Macrae; Eamonn Maher; Annika Lindblom; Samuel Rotstein; Bo Nilsson; Jukka-Pekka Mecklin; Gabriela Möslein; Jeremy Jass; Riccardo Fodde; John Mathers; John Burn; D Timothy Bishop
Prevalence of adenomas and hyperplastic polyps in mismatch repair mutation carriers among CAPP2 participants: report by the colorectal adenoma/carcinoma prevention programme 2.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(20):3434-9.
2008: Claudia Gaspar; Joana Cardoso; Patrick Franken; Lia Molenaar; Hans Morreau; Gabriela Möslein; Julian Sampson; Judith M Boer; Renée X de Menezes; Riccardo Fodde
Cross-species comparison of human and mouse intestinal polyps reveals conserved mechanisms in adenomatous polyposis coli (APC)-driven tumorigenesis.
The American journal of pathology 2008;172(5):1363-80.
2007: H F A Vasen; Gabriela Möslein; A Alonso; I Bernstein; L Bertario; I Blanco; John Burn; G Capella; Christoph Engel; Ian M Frayling; Waltraut Friedl; Frederik J Hes; Shirley Hodgson; Jukka-Pekka Mecklin; Pål Møller; Fokko M Nagengast; Y Parc; Laura Renkonen-Sinisalo; Julian R Sampson; Astrid T Stormorken; Juul Wijnen
Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer).
Journal of medical genetics 2007;44(6):353-62.
2006: Nicholas Hearle; Valerie Schumacher; Fred H Menko; Sylviane Olschwang; Lisa A Boardman; Johan J P Gille; Josbert J Keller; Anne Marie Westerman; Rodney J Scott; Wendy Lim; Jill D Trimbath; Francis M Giardiello; Stephen B Gruber; G Johan A Offerhaus; F W M D E Rooij; J H Paul Wilson; Anika Hansmann; Gabriela Möslein; Brigitte Royer-Pokora; Tilman Vogel; R K S Phillips; Allan D Spigelman; richard Houlston
STK11 status and intussusception risk in Peutz-Jeghers syndrome.
Journal of medical genetics 2006;43(8):e41.
2006: Nicholas Hearle; Valerie Schumacher; Fred H Menko; Sylviane Olschwang; Lisa A Boardman; Johan J P Gille; Josbert J Keller; Anne Marie Westerman; Rodney J Scott; Wendy Lim; Jill D Trimbath; Francis M Giardiello; Stephen B Gruber; G Johan A Offerhaus; Felix W M de Rooij; J H Paul Wilson; Anika Hansmann; Gabriela Möslein; Brigitte Royer-Pokora; Tilman Vogel; R K S Phillips; Allan D Spigelman; richard Houlston
Frequency and spectrum of cancers in the Peutz-Jeghers syndrome.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(10):3209-15.
2006: Joana Cardoso; Lia Molenaar; Renée X de Menezes; Monique van Leerdam; Carla Rosenberg; Gabriela Möslein; Julian Sampson; Hans Morreau; Judith M Boer; Riccardo Fodde
Chromosomal instability in MYH- and APC-mutant adenomatous polyps.
Cancer research 2006;66(5):2514-9.
2005: Gabriela Möslein; Christian Ohmann; M Wenzel
[Prophylactic surgery for hereditary non-polyposis colorectal cancer].
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 2005;76(12):1135-44.
2005: Heleen van der Klift; Juul Wijnen; Anja Wagner; Paul Verkuilen; Carli Tops; Robyn Otway; M R J Kohonen-Corish; H F A Vasen; Cristina Oliani; Daniela Barana; Pal Moller; Celia Delozier-Blanchet; Pierre Hutter; William D Foulkes; Henry T Lynch; John Burn; Gabriela Möslein; Riccardo Fodde
Molecular characterization of the spectrum of genomic deletions in the mismatch repair genes MSH2, MLH1, MSH6, and PMS2 responsible for hereditary nonpolyposis colorectal cancer (HNPCC).
Genes, chromosomes & cancer 2005;44(2):123-38.
2005: Valerie Schumacher; Tilman Vogel; Barbara Leube; Christiane Driemel; Timm Goecke; Gabriela Möslein; Brigitte Royer-Pokora
STK11 genotyping and cancer risk in Peutz-Jeghers syndrome.
Journal of medical genetics 2005;42(5):428-35.
2005: T Vogel; Christiane Driemel; A Hauser; Anika Hansmann; S Lange; M Jonas; Gabriela Möslein
[Comparison of different stool tests for the detection of cancer of the colon].
Deutsche medizinische Wochenschrift (1946) 2005;130(14):872-7.
2005: Stefan M Woerner; Matthias Kloor; Annegret Mueller; Josef Rueschoff; Nicolaus Friedrichs; Reinhard Buettner; Moriz Buzello; Peter Kienle; Hanns-Peter Knaebel; Erdmute Kunstmann; Constanze Pagenstecher; Hans K Schackert; Gabriela Möslein; Holger Vogelsang; Magnus von Knebel Doeberitz; Johannes Gebert
Microsatellite instability of selective target genes in HNPCC-associated colon adenomas.
Oncogene 2005;24(15):2525-35.
2005: Karsten Schulmann; Stephan Hollerbach; Katja Kraus; Jörg Willert; Tilman Vogel; Gabriela Möslein; Christian Pox; Markus Reiser; Anke Reinacher-Schick; Wolff Schmiegel
Feasibility and diagnostic utility of video capsule endoscopy for the detection of small bowel polyps in patients with hereditary polyposis syndromes.
The American journal of gastroenterology 2005;100(1):27-37.
2004: Stefan Aretz; Siegfried Uhlhaas; Yuli Sun; Constanze Pagenstecher; Elisabeth Mangold; Reiner Caspari; Gabriela Möslein; Karsten Schulmann; Peter Propping; Waltraut Friedl
Familial adenomatous polyposis: aberrant splicing due to missense or silent mutations in the APC gene.
Human mutation 2004;24(5):370-80.
2004: Jens Plaschke; Stefan Krüger; Wolfgang Dietmaier; Johannes Gebert; Christian Sutter; Elisabeth Mangold; Constanze Pagenstecher; Elke Holinski-Feder; Karsten Schulmann; Gabriela Möslein; Josef Rüschoff; Christoph Engel; Gareth Evans; Hans K Schackert
Eight novel MSH6 germline mutations in patients with familial and nonfamilial colorectal cancer selected by loss of protein expression in tumor tissue.
Human mutation 2004;23(3):285.
2004: Joana Cardoso; Lia Molenaar; Renée X de Menezes; Carla Rosenberg; Hans Morreau; Gabriela Möslein; Riccardo Fodde; Judith M Boer
Genomic profiling by DNA amplification of laser capture microdissected tissues and array CGH.
Nucleic acids research 2004;32(19):e146.
2003: Hanne Meijers-Heijboer; Juul Wijnen; H F A Vasen; Marijke Wasielewski; Anja Wagner; Antoinette Hollestelle; Fons Elstrodt; Renate van den Bos; Anja de Snoo; Grace Tjon A Fat; Cecile T M Brekelmans; Shantie Jagmohan; Patrick Franken; Paul Verkuijlen; Ans M W van den Ouweland; Pamela Chapman; Carli Tops; Gabriela Möslein; John Burn; Henry T Lynch; Jan G M Klijn; Riccardo Fodde; Mieke Schutte
The CHEK2 1100delC mutation identifies families with a hereditary breast and colorectal cancer phenotype.
American journal of human genetics 2003;72(5):1308-14.
2003: Gabriela Möslein; Steffen Pistorius; Hans-Detlev Saeger; Hans K Schackert
Preventive surgery for colon cancer in familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer syndrome.
Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie 2003;388(1):9-16.
2003: Astrid T Stormorken; Wolfram Müller; Annika Lindblom; Ketil Heimdal; Steinar Aase; Inger Marie Bowitz Lothe; Tove Norèn; Juul Wijnen; Gabriela Möslein; Pål Møller
The inframe MSH2 codon 596 deletion is linked with HNPCC and associated with lack of MSH2 protein in tumours.
Familial cancer 2003;2(1):9-13.
2003: Gabriela Möslein
Clinical implications of molecular diagnosis in hereditary nonpolyposis colorectal cancer.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2003;162():73-8.
2002: Maria Planck; Eva Rambech; Gabriela Möslein; Wolfram Müller; Håkan Olsson; Mef Nilbert
High frequency of microsatellite instability and loss of mismatch-repair protein expression in patients with double primary tumors of the endometrium and colorectum.
Cancer 2002;94(9):2502-10.
2002: Sybille Höwer; Gabriela Möslein; A Unger; T Vogel; Timm Goecke; L Alberti
[Psychooncological aspects in the care of females in HNPCC families].
Zentralblatt für Gynäkologie 2002;124(1):71-5.
2001: Waltraut Friedl; Reiner Caspari; Marlies Sengteller; Siegfried Uhlhaas; Christof Lamberti; Matthias Jungck; Martina Kadmon; M Wolf; J Fahnenstich; Johannes Gebert; Gabriela Möslein; Elisabeth Mangold; Peter Propping
Can APC mutation analysis contribute to therapeutic decisions in familial adenomatous polyposis? Experience from 680 FAP families.
Gut 2001;48(4):515-21.
2001: Gabriela Möslein
[Hereditary nonpolyposis colorectal carcinoma (HNPCC): surgical aspects].
Praxis 2001;90(12):483-9.
2001: Astrid T Stormorken; W Müller; B Lemkemeyer; Jaran Apold; Juul Wijnen; Riccardo Fodde; Gabriela Möslein; Pål Møller
Prediction of the outcome of genetic testing in HNPCC kindreds using the revised Amsterdam criteria and immunohistochemistry.
Familial cancer 2001;1(3-4):169-73.
2001: W Müller; Lawrence J Burgart; R Krause-Paulus; Stephen N Thibodeau; M Almeida; Tina Bocker Edmonston; C R Boland; Christian Sutter; Jeremy R Jass; A Lindblom; J Lubinski; K MacDermot; D S Sanders; Hans Morreau; Annegret Müller; Cristina Oliani; T Orntoft; Maurizio Ponz de Leon; C Rosty; M Rodriguez-Bigas; Josef Rüschoff; Andrew Ruszkiewicz; J Sabourin; R Salovaara; Gabriela Möslein
The reliability of immunohistochemistry as a prescreening method for the diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC)--results of an international collaborative study.
Familial cancer 2001;1(2):87-92.
2001: Gabriela Möslein; J Albrecht; Christian Ohmann; Hans K Schackert
[Preventive therapy of HNPCC--a study concept].
Kongressband / Deutsche Gesellschaft für Chirurgie. Deutsche Gesellschaft für Chirurgie. Kongress 2001;118():213-7.
2000: G Peterschulte; T Lickfeld; Gabriela Möslein
[The desmoid problem].
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 2000;71(8):894-903.
2000: Gabriela Möslein; R Krause-Paulus; R Hegger; G Peterschulte; Tilman Vogel
Clinical aspects of hereditary nonpolyposis colorectal cancer.
Annals of the New York Academy of Sciences 2000;910():75-83; discussion 83-4.
2000: Tilman Vogel; Valerie Schumacher; A Saleh; J Trojan; Gabriela Möslein
Extraintestinal polyps in Peutz-Jeghers syndrome: presentation of four cases and review of the literature. Deutsche Peutz-Jeghers-Studiengruppe.
International journal of colorectal disease 2000;15(2):118-23.
1999: Juul Wijnen; Wiljo J F De Leeuw; H F A Vasen; Heleen van der Klift; Pål Møller; Astrid T Stormorken; Hanne Meijers-Heijboer; Dick Lindhout; Fred H Menko; Sandra Vossen; Gabriela Möslein; Carli Tops; Annette H J T Bröcker-Vriends; Y Wu; Robert M W Hofstra; Rolf Sijmons; Cees J Cornelisse; Hans Morreau; Riccardo Fodde
Familial endometrial cancer in female carriers of MSH6 germline mutations.
Nature genetics 1999;23(2):142-4.
1998: PM Sagar; Gabriela Möslein; Roger R Dozois
Management of desmoid tumors in patients after ileal pouch-anal anastomosis for familial adenomatous polyposis.
Diseases of the colon and rectum 1998;41(11):1350-5; discussion 1355-6.
1998: Gabriela Möslein; H Nelson; Stephen N Thibodeau; Roger R Dozois
[Rectal carcinomas in HNPCC].
Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress 1998;115():1467-9.
1998: Sandra Vossen; Gabriela Möslein; M Katzer; Helmut E Gabbert; W Müller; C Wirtz; Peter E Goretzki; Hans-Dietrich Röher
[Protein expression of hMSH2 and hMLH1 in HNPCC: evaluation of a prescreening method].
Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress 1998;115():1461-3.
1995: Gabriela Möslein; A Buhre; Sandra Vossen; Hans-Dietrich Röher
[Hereditary non-polyposis colorectal cancer (HNPCC)--a determination ofthe current status. Report on the 1st Symposium of the German HNPCC Study Group in Düsseldorf 9 December 1994 and the 1st Professional Group Meeting 31 March 1995. Initiating a concerted action in Germany].
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 1995;66(8):834-7.
1994: R Hesterberg; F Müller; WU Schmidt; Gabriela Möslein; B Lammers
[Sigmoid diverticulitis in immunosuppressive drug therapy].
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 1994;65(10):873-6.