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Brooke Mossman

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Arti Shukla; Pamela M Vacek; Harvey I Pass; Mutlay Sayan; Stacie L Beuschel; Christopher Cason; Jedd Hillegass; Maximilian B MacPherson; Jill M Miller; Brooke T Mossman
Extracellular signal-regulated kinase 5: a potential therapeutic target for malignant mesotheliomas.
Brooke T Mossman; Arti Shukla; Anish Thomas; Claire F Verschraegen; Nicholas H Heintz; Raffit Hassan
New insights into understanding the mechanisms, pathogenesis, and management of malignant mesotheliomas.
Paul M Peeters; Timothy N Perkins; Brooke T Mossman; Emiel F M Wouters; Niki L Reynaert
Silica induces NLRP3 inflammasome activation in human lung epithelial cells.

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2013: Arti Shukla; Pamela M Vacek; Harvey I Pass; Mutlay Sayan; Stacie L Beuschel; Christopher Cason; Jedd Hillegass; Maximilian B MacPherson; Jill M Miller; Brooke T Mossman
Extracellular signal-regulated kinase 5: a potential therapeutic target for malignant mesotheliomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013;19(8):2071-83.
2013: Brooke T Mossman; Arti Shukla; Anish Thomas; Claire F Verschraegen; Nicholas H Heintz; Raffit Hassan
New insights into understanding the mechanisms, pathogenesis, and management of malignant mesotheliomas.
The American journal of pathology 2013;182(4):1065-77.
2013: Paul M Peeters; Timothy N Perkins; Brooke T Mossman; Emiel F M Wouters; Niki L Reynaert
Silica induces NLRP3 inflammasome activation in human lung epithelial cells.
Particle and fibre toxicology 2013;10():3.
2012: Sherrill L Macura; Timothy N Perkins; Mutlay Sayan; Arti Shukla; Jeremy L Steinbacher; Douglas J Taatjes; Stacie L Beuschel; Kelly J Butnor; Khan Hekmatyar; Jedd M Hillegass; Risto A Kauppinen; Christopher C Landry; Melissa J Lathrop; Maximilian B MacPherson; Brooke T Mossman
A multifunctional mesothelin antibody-tagged microparticle targets human mesotheliomas.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2012;60(9):658-74.
2012: Timothy N Perkins; Niki L Reynaert; Arti Shukla; Chad Steele; Jeremy L Steinbacher; Emiel F M Wouters; Christopher C Landry; Sherrill A Lathrop; Paul M Peeters; Brooke T Mossman
Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells.
Particle and fibre toxicology 2012;9(1):6.
2011: Arti Shukla; William A Swain; Joseph R Testa; Kenneth J O'Byrne; Harvey I Pass; Trisha F Barrett; Stephen P Faux; Naomi K Fukagawa; Jedd M Hillegass; Maximmilian MacPherson; Brooke T Mossman
An extracellular signal-regulated kinase 2 survival pathway mediates resistance of human mesothelioma cells to asbestos-induced injury.
American journal of respiratory cell and molecular biology 2011;45(5):906-14.
2011: Arti Shukla; Joseph R Testa; Pamela M Vacek; Harvey I Pass; Stacie L Beuschel; Kelly J Butnor; Michele Carbone; Nicholas H Heintz; Jedd M Hillegass; Maximilian B MacPherson; Brooke T Mossman
ERK2 is essential for the growth of human epithelioid malignant mesotheliomas.
International journal of cancer. Journal international du cancer 2011;129(5):1075-86.
2011: Jedd M Hillegass; Steven R Blumen; Kai Cheng; Maximilian B MacPherson; Vlada Alexeeva; Sherrill A Lathrop; Stacie L Beuschel; Jeremy L Steinbacher; Kelly J Butnor; Maria E Ramos-Niño; Arti Shukla; Ted A James; Daniel J Weiss; Douglas J Taatjes; Harvey I Pass; Michele Carbone; Christopher C Landry; Brooke T Mossman
Increased efficacy of doxorubicin delivered in multifunctional microparticles for mesothelioma therapy.
International journal of cancer. Journal international du cancer 2011;129(1):233-44.
2011: Tara Sabo- Attwood; Maria E Ramos-Nino; Maria Eugenia-Ariza; Maximmilian MacPherson; Kelly J Butnor; Pamela C Vacek; Sean P McGee; Jessica C Clark; Chad Steele; Brooke T Mossman
Osteopontin modulates inflammation, mucin production, and gene expression signatures after inhalation of asbestos in a murine model of fibrosis.
The American journal of pathology 2011;178(5):1975-85.
2011: Brooke T Mossman; Morton Lippmann; Thomas W Hesterberg; Karl T Kelsey; Aaron Barchowsky; James C Bonner
Pulmonary endpoints (lung carcinomas and asbestosis) following inhalation exposure to asbestos.
Journal of toxicology and environmental health. Part B, Critical reviews 2011;14(1-4):76-121.
2010: Jeremy L Steinbacher; Sherrill A Lathrop; Kai Cheng; Jedd M Hillegass; Kelly J Butnor; Risto A Kauppinen; Brooke T Mossman; Christopher C Landry
Gd-labeled microparticles in MRI: in vivo imaging of microparticles after intraperitoneal injection.
Small (Weinheim an der Bergstrasse, Germany) 2010;6(23):2678-82.
2010: Kai Cheng; Steven R Blumen; Maximilian B MacPherson; Jeremy L Steinbacher; Brooke T Mossman; Christopher C Landry
Enhanced uptake of porous silica microparticles by bifunctional surface modification with a targeting antibody and a biocompatible polymer.
ACS applied materials & interfaces 2010;2(9):2489-95.
2010: Jedd M Hillegass; Arti Shukla; Sherrill A Lathrop; Maximilian B MacPherson; Stacie L Beuschel; Kelly J Butnor; Joseph R Testa; Harvey I Pass; Michele Carbone; Chad Steele; Brooke T Mossman
Inflammation precedes the development of human malignant mesotheliomas in a SCID mouse xenograft model.
Annals of the New York Academy of Sciences 2010;1203():7-14.
2010: Jedd M Hillegass; Arti Shukla; Sherrill A Lathrop; Maximilian B MacPherson; Naomi K Fukagawa; Brooke T Mossman
Assessing nanotoxicity in cells in vitro.
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 2010;2(3):219-31.
2010: Nicholas H Heintz; Yvonne M W Janssen-Heininger; Brooke T Mossman
Asbestos, lung cancers, and mesotheliomas: from molecular approaches to targeting tumor survival pathways.
American journal of respiratory cell and molecular biology 2010;42(2):133-9.
2010: Arti Shukla; Jedd M Hillegass; Maximilian B MacPherson; Stacie L Beuschel; Pamela M Vacek; Harvey I Pass; Michele Carbone; Joseph R Testa; Brooke T Mossman
Blocking of ERK1 and ERK2 sensitizes human mesothelioma cells to doxorubicin.
Molecular cancer 2010;9():314.
2010: Jedd M Hillegass; Arti Shukla; Maximilian B MacPherson; Sherrill A Lathrop; Vlada Alexeeva; Timothy N Perkins; Albert van der Vliet; Pamela M Vacek; Mickey E Gunter; Brooke T Mossman
Mechanisms of oxidative stress and alterations in gene expression by Libby six-mix in human mesothelial cells.
Particle and fibre toxicology 2010;7():26.
2010: Jedd M Hillegass; Arti Shukla; Maximilian B MacPherson; Jeffrey P Bond; Chad Steele; Brooke T Mossman
Utilization of gene profiling and proteomics to determine mineral pathogenicity in a human mesothelial cell line (LP9/TERT-1).
Journal of toxicology and environmental health. Part A 2010;73(5):423-36.
2009: Arti Shukla; Marcus W Bosenberg; Maximmilian MacPherson; Kelly J Butnor; Nicholas H Heintz; Harvey I Pass; Michele Carbone; Joseph R Testa; Brooke T Mossman
Activated cAMP response element binding protein is overexpressed in human mesotheliomas and inhibits apoptosis.
The American journal of pathology 2009;175(5):2197-206.
2009: Arti Shukla; Maximmilian MacPherson; Jedd Hillegass; Maria E Ramos-Nino; Vlada Alexeeva; Pamela M Vacek; Jeffrey P Bond; Harvey I Pass; Chad Steele; Brooke T Mossman
Alterations in gene expression in human mesothelial cells correlate with mineral pathogenicity.
American journal of respiratory cell and molecular biology 2009;41(1):114-23.
2009: Astrid Haegens; Peter Heeringa; Robert Jan van Suylen; Chad Steele; Yasuaki Aratani; Robert J J O'Donoghue; Steven E Mutsaers; Brooke T Mossman; Emiel F M Wouters; Juanita Vernooy
Myeloperoxidase deficiency attenuates lipopolysaccharide-induced acute lung inflammation and subsequent cytokine and chemokine production.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(12):7990-6.
2009: SA Buder-Hoffmann; Arti Shukla; Trisha F Barrett; Maximmilian MacPherson; Karen M Lounsbury; Brooke T Mossman
A protein kinase Cdelta-dependent protein kinase D pathway modulates ERK1/2 and JNK1/2 phosphorylation and Bim-associated apoptosis by asbestos.
The American journal of pathology 2009;174(2):449-59.
2008: J P Stevens; J Zahardis; Maximmilian MacPherson; Brooke T Mossman; Giuseppe A Petrucci
A new method for quantifiable and controlled dosage of particulate matter for in vitro studies: the electrostatic particulate dosage and exposure system (EPDExS).
Toxicology in vitro : an international journal published in association with BIBRA 2008;22(7):1768-74.
2008: Brooke T Mossman
Assessment of the pathogenic potential of asbestiform vs. nonasbestiform particulates (cleavage fragments) in in vitro (cell or organ culture) models and bioassays.
Regulatory toxicology and pharmacology : RTP 2008;52(1 Suppl):S200-3.
2008: Naomi K Fukagawa; Muyao Li; Tara Sabo- Attwood; Cynthia R Timblin; Kelly J Butnor; Jessica Gagne; Chad Steele; Douglas J Taatjes; Sally Huber; Brooke T Mossman
Inhaled asbestos exacerbates atherosclerosis in apolipoprotein E-deficient mice via CD4+ T cells.
Environmental health perspectives 2008;116(9):1218-25.
2008: Yvonne M W Janssen-Heininger; Brooke T Mossman; Nicholas H Heintz; Henry J Forman; Balaraman Kalyanaraman; TOREN FINKEL; Jonathan S Stamler; Sue Goo Rhee; Albert van der Vliet
Redox-based regulation of signal transduction: principles, pitfalls, and promises.
Free radical biology & medicine 2008;45(1):1-17.
2008: Catherine Dostert; Virginie Pétrilli; Robin Van Bruggen; Chad Steele; Brooke T Mossman; Jürg Tschopp
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica.
Science (New York, N.Y.) 2008;320(5876):674-7.
2008: Christy A Barlow; Kajorn Kitiphongspattana; Nazli Siddiqui; Michael W Roe; Brooke T Mossman; Karen M Lounsbury
Protein kinase A-mediated CREB phosphorylation is an oxidant-induced survival pathway in alveolar type II cells.
Apoptosis : an international journal on programmed cell death 2008;13(5):681-92.
2008: Christopher B Manning; Tara Sabo- Attwood; RF Robledo; Maximmilian MacPherson; Mercedes Rincón; Pamela M Vacek; David Hemenway; Douglas J Taatjes; Patty J Lee; Brooke T Mossman
Targeting the MEK1 cascade in lung epithelium inhibits proliferation and fibrogenesis by asbestos.
American journal of respiratory cell and molecular biology 2008;38(5):618-26.
2008: Maria E Ramos-Nino; Steven R Blumen; Tara Sabo- Attwood; Harvey I Pass; Michele Carbone; Joseph R Testa; Deborah A Altomare; Brooke T Mossman
HGF mediates cell proliferation of human mesothelioma cells through a PI3K/MEK5/Fra-1 pathway.
American journal of respiratory cell and molecular biology 2008;38(2):209-17.
2008: Jamie Levis; Roberto Loi; Kelly J Butnor; Pamela M Vacek; Chad Steele; Brooke T Mossman; Daniel J Weiss
Decreased asbestos-induced lung inflammation and fibrosis after radiation and bone marrow transplant.
American journal of respiratory cell and molecular biology 2008;38(1):16-25.
2007: Brooke T Mossman; Arti Shukla; Naomi K Fukagawa
Highlight Commentary on "Oxidative stress and lipid mediators induced in alveolar macrophages by ultrafine particles".
Free radical biology & medicine 2007;43(4):504-5.
2007: Christy A Barlow; Trisha F Barrett; Arti Shukla; Brooke T Mossman; Karen M Lounsbury
Asbestos-mediated CREB phosphorylation is regulated by protein kinase A and extracellular signal-regulated kinases 1/2.
American journal of physiology. Lung cellular and molecular physiology 2007;292(6):L1361-9.
2007: Steven R Blumen; Kai Cheng; Maria E Ramos-Nino; Douglas J Taatjes; Daniel J Weiss; Christopher C Landry; Brooke T Mossman
Unique uptake of acid-prepared mesoporous spheres by lung epithelial and mesothelioma cells.
American journal of respiratory cell and molecular biology 2007;36(3):333-42.
2007: Astrid Haegens; Trisha F Barrett; Joanna Gell; Arti Shukla; Maximmilian MacPherson; Pamela M Vacek; Matthew E Poynter; Kelly J Butnor; Yvonne M W Janssen-Heininger; Chad Steele; Brooke T Mossman
Airway epithelial NF-kappaB activation modulates asbestos-induced inflammation and mucin production in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(3):1800-8.
2007: Maria E Ramos-Nino; Steven R Blumen; Harvey I Pass; Brooke T Mossman
Fra-1 governs cell migration via modulation of CD44 expression in human mesotheliomas.
Molecular cancer 2007;6():81.
2007: Brooke T Mossman; Paul J A Borm; Vincent Castranova; Daniel L Costa; Kenneth Donaldson; Steven R Kleeberger
Mechanisms of action of inhaled fibers, particles and nanoparticles in lung and cardiovascular diseases.
Particle and fibre toxicology 2007;4():4.
2007: Arti Shukla; Karen M Lounsbury; Trisha F Barrett; Joanna Gell; Mercedes Rincon; Kelly J Butnor; Douglas J Taatjes; Gerald S Davis; Pamela M Vacek; Keiichi I Nakayama; Keiko Nakayama; Chad Steele; Brooke T Mossman
Asbestos-induced peribronchiolar cell proliferation and cytokine production are attenuated in lungs of protein kinase C-delta knockout mice.
The American journal of pathology 2007;170(1):140-51.
2006: Muyao Li; Jen-Fu Chiu; Brooke T Mossman; Naomi K Fukagawa
Down-regulation of manganese-superoxide dismutase through phosphorylation of FOXO3a by Akt in explanted vascular smooth muscle cells from old rats.
The Journal of biological chemistry 2006;281(52):40429-39.
2006: Kimberley A O'Hara; Antonia A Nemec; Jawed Alam; Linda R Klei; Brooke T Mossman; Aaron Barchowsky
Chromium (VI) inhibits heme oxygenase-1 expression in vivo and in arsenic-exposed human airway epithelial cells.
Journal of cellular physiology 2006;209(1):113-21.
2006: Barbara Kroczynska; Rochelle Cutrone; Maurizio Bocchetta; Haining Yang; Amira G Elmishad; Pamela M Vacek; Maria E Ramos-Nino; Brooke T Mossman; Harvey I Pass; Michele Carbone
Crocidolite asbestos and SV40 are cocarcinogens in human mesothelial cells and in causing mesothelioma in hamsters.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(38):14128-33.
2006: Haining Yang; Maurizio Bocchetta; Barbara Kroczynska; Amira G Elmishad; Yuanbin Chen; Zemin Liu; Concetta Bubici; Brooke T Mossman; Harvey I Pass; Joseph R Testa; Guido Franzoso; Michele Carbone
TNF-alpha inhibits asbestos-induced cytotoxicity via a NF-kappaB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(27):10397-402.
2006: Maria E Ramos-Nino; Joseph R Testa; Deborah A Altomare; Harvey I Pass; Michele Carbone; Maurizio Bocchetta; Brooke T Mossman
Cellular and molecular parameters of mesothelioma.
Journal of cellular biochemistry 2006;98(4):723-34.
2006: Brooke T Mossman; Karen M Lounsbury; SEKHAR POTHIREDDY
Oxidants and signaling by mitogen-activated protein kinases in lung epithelium.
American journal of respiratory cell and molecular biology 2006;34(6):666-9.
2006: Kenneth B Adler; Steven D Shapiro; Marianne Gallup; Reen Wu; Scott H Randell; Michael J Holtzman; Christopher M Evans; David B Jacoby; Stephanie Holmgren; Mary C Rose; Brooke T Mossman; Alice Prince; SEKHAR POTHIREDDY; C William Davis; Michael A Matthay
Airway epithelium, inflammation, and mechanisms of disease: A tribute to Carol B. Basbaum.
American journal of respiratory cell and molecular biology 2006;34(5):523-6.
2006: Arti Shukla; Trisha F Barrett; Keiichi I Nakayama; Kieko Nakayama; Brooke T Mossman; Karen M Lounsbury
Transcriptional up-regulation of MMP12 and MMP13 by asbestos occurs via a PKCdelta-dependent pathway in murine lung.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(7):997-9.
2006: Muyao Li; Rui-Ming Liu; Cynthia R Timblin; Suzanne G Meyer; Brooke T Mossman; Naomi K Fukagawa
Age affects ERK1/2 and NRF2 signaling in the regulation of GCLC expression.
Journal of cellular physiology 2006;206(2):518-25.
2006: Christopher B Manning; Brooke T Mossman; Douglas J Taatjes
Analysis of asbestos-induced gene expression changes in bronchiolar epithelial cells using laser capture microdissection and quantitative reverse transcriptase-polymerase chain reaction.
Methods in molecular biology (Clifton, N.J.) 2006;319():231-6.
2006: Maria Stern; Douglas J Taatjes; Brooke T Mossman
Multifluorescence labeling techniques and confocal laser scanning microscopy on lung tissue.
Methods in molecular biology (Clifton, N.J.) 2006;319():67-76.
2006: Patty J Lee; Xuchen Zhang; Peiying Shan; Bing Ma; Chun Geun Lee; Robert J Homer; Zhou Zhu; Mercedes Rincon; Brooke T Mossman; Jack A Elias
ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo.
The Journal of clinical investigation 2006;116(1):163-73.
2006: Christy A Barlow; Arti Shukla; Brooke T Mossman; Karen M Lounsbury
Oxidant-mediated cAMP response element binding protein activation: calcium regulation and role in apoptosis of lung epithelial cells.
American journal of respiratory cell and molecular biology 2006;34(1):7-14.
2005: Michele Carbone; Monica A Rdzanek; Jennifer Rudzinski; Melissa A De Marco; Maurizio Bocchetta; Maria Ramos Niño; Brooke T Mossman; Harvey I Pass
SV40 detection in human tumor specimens.
Cancer research 2005;65(21):10120-1.
2005: Astrid Haegens; Albert van der Vliet; Kelly J Butnor; Nicholas H Heintz; Douglas J Taatjes; David Hemenway; Pamela M Vacek; Bruce Freeman; Stanley L Hazen; Marie Luise Brennan; Brooke T Mossman
Asbestos-induced lung inflammation and epithelial cell proliferation are altered in myeloperoxidase-null mice.
Cancer research 2005;65(21):9670-7.
2005: Tara Sabo- Attwood; Maria E Ramos-Nino; Jeffrey Bond; Kelly J Butnor; Nicholas H Heintz; Achim D Gruber; Chad Steele; Douglas J Taatjes; Pamela M Vacek; Brooke T Mossman
Gene expression profiles reveal increased mClca3 (Gob5) expression and mucin production in a murine model of asbestos-induced fibrogenesis.
The American journal of pathology 2005;167(5):1243-56.
2005: Deborah A Altomare; Huihong You; Guang-Hui Xiao; Maria E Ramos-Nino; Kristine L Skele; Assunta De Rienzo; Suresh C Jhanwar; Brooke T Mossman; Agnes B Kane; Joseph R Testa
Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth.
Oncogene 2005;24(40):6080-9.
2005: Maria E Ramos-Nino; Giovina Vianale; Tara Sabo- Attwood; Luciano Mutti; Camilo Porta; Nicholas H Heintz; Brooke T Mossman
Human mesothelioma cells exhibit tumor cell-specific differences in phosphatidylinositol 3-kinase/AKT activity that predict the efficacy of Onconase.
Molecular cancer therapeutics 2005;4(5):835-42.
2004: Brooke T Mossman; George Klein; Harald zur Hausen
Modern criteria to determine the etiology of human carcinogens.
Seminars in cancer biology 2004;14(6):449-52.
2004: Arti Shukla; Trisha Flanders; Karen M Lounsbury; Brooke T Mossman
The gamma-glutamylcysteine synthetase and glutathione regulate asbestos-induced expression of activator protein-1 family members and activity.
Cancer research 2004;64(21):7780-6.
2004: Ziqiang Yuan; Douglas J Taatjes; Brooke T Mossman; Nicholas H Heintz
The duration of nuclear extracellular signal-regulated kinase 1 and 2 signaling during cell cycle reentry distinguishes proliferation from apoptosis in response to asbestos.
Cancer research 2004;64(18):6530-6.
2004: Arti Shukla; Pamela Vacek; Brooke T Mossman
Dose-Response Relationships in Expression of Biomarkers of Cell Proliferation in in vitro Assays and Inhalation Experiments.
Nonlinearity in biology, toxicology, medicine 2004;2(2):117-28.
2004: Michael Jung; Steven M Grunberg; Cynthia R Timblin; Sylke Buder-Hoffman; Pamela M Vacek; Douglas J Taatjes; Brooke T Mossman
Paclitaxel and vinorelbine cause synergistic increases in apoptosis but not in microtubular disruption in human lung adenocarcinoma cells (A-549).
Histochemistry and cell biology 2004;121(2):115-21.
2004: Luca Scapoli; Maria E Ramos-Nino; Marcella Martinelli; Brooke T Mossman
Src-dependent ERK5 and Src/EGFR-dependent ERK1/2 activation is required for cell proliferation by asbestos.
Oncogene 2004;23(3):805-13.
2003: Muyao Li; Brooke T Mossman; Emily Kolpa; Cynthia R Timblin; Arti Shukla; Douglas J Taatjes; Naomi K Fukagawa
Age-related differences in MAP kinase activity in VSMC in response to glucose or TNF-alpha.
Journal of cellular physiology 2003;197(3):418-25.
2003: Arti Shukla; Michael Jung; Maria Stern; Naomi K Fukagawa; Douglas J Taatjes; Dennis Sawyer; Bennett Van Houten; Brooke T Mossman
Asbestos induces mitochondrial DNA damage and dysfunction linked to the development of apoptosis.
American journal of physiology. Lung cellular and molecular physiology 2003;285(5):L1018-25.
2003: Maria E Ramos-Nino; Nicholas H Heintz; Luca Scappoli; Marcella Martinelli; Susan J Land; Norma Nowak; Astrid Haegens; Brian Manning; Nicole Manning; Maximmilian MacPherson; Maria Stern; Brooke T Mossman
Gene profiling and kinase screening in asbestos-exposed epithelial cells and lungs.
American journal of respiratory cell and molecular biology 2003;29(3 Suppl):S51-8.
2003: Arti Shukla; Maria E Ramos-Nino; Brooke T Mossman
Cell signaling and transcription factor activation by asbestos in lung injury and disease.
The international journal of biochemistry & cell biology 2003;35(8):1198-209.
2003: Arti Shukla; Maria Stern; Karen M Lounsbury; Trisha Flanders; Brooke T Mossman
Asbestos-induced apoptosis is protein kinase C delta-dependent.
American journal of respiratory cell and molecular biology 2003;29(2):198-205.
2003: Maria E Ramos-Nino; Luca Scapoli; Marcella Martinelli; Susan J Land; Brooke T Mossman
Microarray analysis and RNA silencing link fra-1 to cd44 and c-met expression in mesothelioma.
Cancer research 2003;63(13):3539-45.
2003: Arti Shukla; Mary Gulumian; Tom K Hei; David Kamp; Qamar Rahman; Brooke T Mossman
Multiple roles of oxidants in the pathogenesis of asbestos-induced diseases.
Free radical biology & medicine 2003;34(9):1117-29.
2003: Brooke T Mossman
Introduction to serial reviews on the role of reactive oxygen and nitrogen species (ROS/RNS) in lung injury and diseases.
Free radical biology & medicine 2003;34(9):1115-6.
2003: Andrew B Cummins; Cathy Palmer; Brooke T Mossman; Douglas J Taatjes
Persistent localization of activated extracellular signal-regulated kinases (ERK1/2) is epithelial cell-specific in an inhalation model of asbestosis.
The American journal of pathology 2003;162(3):713-20.
2002: SEKHAR POTHIREDDY; Brooke T Mossman
Role and regulation of activator protein-1 in toxicant-induced responses of the lung.
American journal of physiology. Lung cellular and molecular physiology 2002;283(6):L1161-78.
2002: Maria E Ramos-Nino; Cynthia R Timblin; Brooke T Mossman
Mesothelial cell transformation requires increased AP-1 binding activity and ERK-dependent Fra-1 expression.
Cancer research 2002;62(21):6065-9.
2002: Catrin Albrecht; Paul J A Borm; Brigitte Adolf; Cynthia R Timblin; Brooke T Mossman
In vitro and in vivo activation of extracellular signal-regulated kinases by coal dusts and quartz silica.
Toxicology and applied pharmacology 2002;184(1):37-45.
2002: Christopher B Manning; Andrew B Cummins; Michael W Jung; Ingrid Berlanger; Cynthia R Timblin; Cathy Palmer; Douglas J Taatjes; David Hemenway; Pamela M Vacek; Brooke T Mossman
A mutant epidermal growth factor receptor targeted to lung epithelium inhibits asbestos-induced proliferation and proto-oncogene expression.
Cancer research 2002;62(15):4169-75.
2002: Karen M Lounsbury; Maria Stern; Douglas J Taatjes; Susan Jaken; Brooke T Mossman
Increased localization and substrate activation of protein kinase C delta in lung epithelial cells following exposure to asbestos.
The American journal of pathology 2002;160(6):1991-2000.
2002: Maria E Ramos-Nino; Astrid Haegens; Arti Shukla; Brooke T Mossman
Role of mitogen-activated protein kinases (MAPK) in cell injury and proliferation by environmental particulates.
Molecular and cellular biochemistry 2002;234-235(1-2):111-8.
2002: Andrea K Hubbard; Cynthia R Timblin; Arti Shukla; Mercedes Rincón; Brooke T Mossman
Activation of NF-kappaB-dependent gene expression by silica in lungs of luciferase reporter mice.
American journal of physiology. Lung cellular and molecular physiology 2002;282(5):L968-75.
2002: Cynthia R Timblin; Arti Shukla; Ingrid Berlanger; Kelly A BeruBe; Andrew Churg; Brooke T Mossman
Ultrafine airborne particles cause increases in protooncogene expression and proliferation in alveolar epithelial cells.
Toxicology and applied pharmacology 2002;179(2):98-104.
2002: Christopher B Manning; Val Vallyathan; Brooke T Mossman
Diseases caused by asbestos: mechanisms of injury and disease development.
International immunopharmacology 2002;2(2-3):191-200.
2002: Brooke T Mossman; Dieter C Gruenert
SV40, growth factors, and mesothelioma: another piece of the puzzle.
American journal of respiratory cell and molecular biology 2002;26(2):167-70.
2001: Naomi K Fukagawa; Muyao Li; Cynthia R Timblin; Brooke T Mossman
Modulation of cell injury and survival by high glucose and advancing age.
Free radical biology & medicine 2001;31(12):1560-9.
2001: Andrea K Hubbard; Cynthia R Timblin; M Rincon; Brooke T Mossman
Use of transgenic luciferase reporter mice to determine activation of transcription factors and gene expression by fibrogenic particles.
Chest 2001;120(1 Suppl):24S-25S.
2001: Cynthia R Timblin; RF Robledo; M Rincon; Andrew B Cummins; L Pfeiffer; Brooke T Mossman
Transgenic mouse models to determine the role of epidermal growth factor receptor in epithelial cell proliferation, apoptosis, and asbestosis.
Chest 2001;120(1 Suppl):22S-24S.
2001: SA Buder-Hoffmann; C Palmer; Pamela M Vacek; Douglas J Taatjes; Brooke T Mossman
Different accumulation of activated extracellular signal-regulated kinases (ERK 1/2) and role in cell-cycle alterations by epidermal growth factor, hydrogen peroxide, or asbestos in pulmonary epithelial cells.
American journal of respiratory cell and molecular biology 2001;24(4):405-13.
2001: Arti Shukla; Cynthia R Timblin; Andrea K Hubbard; J Bravman; Brooke T Mossman
Silica-induced activation of c-Jun-NH2-terminal amino kinases, protracted expression of the activator protein-1 proto-oncogene, fra-1, and S-phase alterations are mediated via oxidative stress.
Cancer research 2001;61(5):1791-5.
2001: Kevin E Driscoll; Brian W Howard; Janet M Carter; YM Janssen; Brooke T Mossman; Robert J Isfort
Mitochondrial-derived oxidants and quartz activation of chemokine gene expression.
Advances in experimental medicine and biology 2001;500():489-96.
2000: Arti Shukla; Cynthia R Timblin; Kelly A BeruBe; T Gordon; willie mckinney; Kevin E Driscoll; Pamela M Vacek; Brooke T Mossman
Inhaled particulate matter causes expression of nuclear factor (NF)-kappaB-related genes and oxidant-dependent NF-kappaB activation in vitro.
American journal of respiratory cell and molecular biology 2000;23(2):182-7.
2000: Brooke T Mossman
Signal transduction by oxidants: look who's talking.
Free radical biology & medicine 2000;28(9):1315-6.
2000: M Jung; W P Davis; Douglas J Taatjes; Andrew Churg; Brooke T Mossman
Asbestos and cigarette smoke cause increased DNA strand breaks and necrosis in bronchiolar epithelial cells in vivo.
Free radical biology & medicine 2000;28(8):1295-9.
2000: RF Robledo; SA Buder-Hoffmann; Andrew B Cummins; ES Walsh; Douglas J Taatjes; Brooke T Mossman
Increased phosphorylated extracellular signal-regulated kinase immunoreactivity associated with proliferative and morphologic lung alterations after chrysotile asbestos inhalation in mice.
The American journal of pathology 2000;156(4):1307-16.
2000: SS Murthy; T Shen; Assunta De Rienzo; WC Lee; P C Ferriola; Suresh C Jhanwar; Brooke T Mossman; Jorge Filmus; Joseph R Testa
Expression of GPC3, an X-linked recessive overgrowth gene, is silenced in malignant mesothelioma.
Oncogene 2000;19(3):410-6.
2000: Naomi K Fukagawa; Cynthia R Timblin; S Buder-Hoffman; Brooke T Mossman
Strategies for evaluation of signaling pathways and transcription factors altered in aging.
Antioxidants & redox signaling 2000;2(3):379-89.
1999: Matthew E Poynter; Yvonne M W Janssen-Heininger; SA Buder-Hoffmann; Douglas J Taatjes; Brooke T Mossman
Measurement of oxidant-induced signal transduction proteins using cell imaging.
Free radical biology & medicine 1999;27(11-12):1164-72.
1999: CL Zanella; Cynthia R Timblin; Andrew B Cummins; M Jung; J Goldberg; R Raabe; TR Tritton; Brooke T Mossman
Asbestos-induced phosphorylation of epidermal growth factor receptor is linked to c-fos and apoptosis.
The American journal of physiology 1999;277(4 Pt 1):L684-93.
1999: RF Robledo; Brooke T Mossman
Cellular and molecular mechanisms of asbestos-induced fibrosis.
Journal of cellular physiology 1999;180(2):158-66.
1999: Yvonne M W Janssen-Heininger; I Macara; Brooke T Mossman
Cooperativity between oxidants and tumor necrosis factor in the activation of nuclear factor (NF)-kappaB: requirement of Ras/mitogen-activated protein kinases in the activation of NF-kappaB by oxidants.
American journal of respiratory cell and molecular biology 1999;20(5):942-52.
1999: Brooke T Mossman
Environmental pathology: new directions and opportunities.
Toxicologic pathology 1999;27(2):180-6.
1998: Cynthia R Timblin; Kelly A BeruBe; Andrew Churg; Kevin E Driscoll; T Gordon; David Hemenway; E Walsh; Andrew B Cummins; Pamela M Vacek; Brooke T Mossman
Ambient particulate matter causes activation of the c-jun kinase/stress-activated protein kinase cascade and DNA synthesis in lung epithelial cells.
Cancer research 1998;58(20):4543-7.
1998: Aaron Barchowsky; RR Roussel; Ronald J Krieser; Brooke T Mossman; MD Treadwell
Expression and activity of urokinase and its receptor in endothelial and pulmonary epithelial cells exposed to asbestos.
Toxicology and applied pharmacology 1998;152(2):388-96.
1998: YM Janssen; Kevin E Driscoll; Cynthia R Timblin; DG Hassenbein; Brooke T Mossman
Modulation of mitochondrial gene expression in pulmonary epithelial cells exposed to oxidants.
Environmental health perspectives 1998;106 Suppl 5():1191-5.
1998: Kevin E Driscoll; Janet M Carter; Brian W Howard; DG Hassenbein; YM Janssen; Brooke T Mossman
Crocidolite activates NF-kappa B and MIP-2 gene expression in rat alveolar epithelial cells. Role of mitochondrial-derived oxidants.
Environmental health perspectives 1998;106 Suppl 5():1171-4.
1998: Cynthia R Timblin; G D Guthrie; Y W Janssen; ES Walsh; Pamela M Vacek; Brooke T Mossman
Patterns of c-fos and c-jun proto-oncogene expression, apoptosis, and proliferation in rat pleural mesothelial cells exposed to erionite or asbestos fibers.
Toxicology and applied pharmacology 1998;151(1):88-97.
1998: Brooke T Mossman; Andrew Churg
Mechanisms in the pathogenesis of asbestosis and silicosis.
American journal of respiratory and critical care medicine 1998;157(5 Pt 1):1666-80.
1998: TR Quinlan; Kelly A BeruBe; M P Hacker; Douglas J Taatjes; Cynthia R Timblin; J Goldberg; P Kimberley; P O'Shaughnessy; David Hemenway; J Torino; LA Jimenez; Brooke T Mossman
Mechanisms of asbestos-induced nitric oxide production by rat alveolar macrophages in inhalation and in vitro models.
Free radical biology & medicine 1998;24(5):778-88.
1998: Cynthia R Timblin; YM Janssen; JL Goldberg; Brooke T Mossman
GRP78, HSP72/73, and cJun stress protein levels in lung epithelial cells exposed to asbestos, cadmium, or H2O2.
Free radical biology & medicine 1998;24(4):632-42.
1998: J C Pache; YM Janssen; ES Walsh; TR Quinlan; CL Zanella; R B Low; Douglas J Taatjes; Brooke T Mossman
Increased epidermal growth factor-receptor protein in a human mesothelial cell line in response to long asbestos fibers.
The American journal of pathology 1998;152(2):333-40.
1998: H Fung; Yoke W Kow; Bennett Van Houten; Douglas J Taatjes; Zafer Hatahet; YM Janssen; Pamela M Vacek; Stephen P Faux; Brooke T Mossman
Asbestos increases mammalian AP-endonuclease gene expression, protein levels, and enzyme activity in mesothelial cells.
Cancer research 1998;58(2):189-94.
1997: L A Jiménez; CL Zanella; H Fung; YM Janssen; Pamela M Vacek; Colette Charland; J Goldberg; Brooke T Mossman
Role of extracellular signal-regulated protein kinases in apoptosis by asbestos and H2O2.
The American journal of physiology 1997;273(5 Pt 1):L1029-35.
1997: W P Davis; YM Janssen; Brooke T Mossman; Douglas J Taatjes
Simultaneous triple fluorescence detection of mRNA localization, nuclear DNA, and apoptosis in cultured cells using confocal scanning laser microscopy.
Histochemistry and cell biology 1997;108(4-5):307-11.
1997: YM Janssen; S Matalon; Brooke T Mossman
Differential induction of c-fos, c-jun, and apoptosis in lung epithelial cells exposed to ROS or RNS.
The American journal of physiology 1997;273(4 Pt 1):L789-96.
1997: Brooke T Mossman; Stephen P Faux; YM Janssen; LA Jimenez; Cynthia R Timblin; CL Zanella; J Goldberg; E Walsh; Aaron Barchowsky; Kevin E Driscoll
Cell signaling pathways elicited by asbestos.
Environmental health perspectives 1997;105 Suppl 5():1121-5.
1997: JL Goldberg; CL Zanella; YM Janssen; Cynthia R Timblin; LA Jimenez; Pamela M Vacek; Douglas J Taatjes; Brooke T Mossman
Novel cell imaging techniques show induction of apoptosis and proliferation in mesothelial cells by asbestos.
American journal of respiratory cell and molecular biology 1997;17(3):265-71.
1997: YM Janssen; Kevin E Driscoll; B Howard; TR Quinlan; MD Treadwell; Aaron Barchowsky; Brooke T Mossman
Asbestos causes translocation of p65 protein and increases NF-kappa B DNA binding activity in rat lung epithelial and pleural mesothelial cells.
The American journal of pathology 1997;151(2):389-401.
1997: H Fung; TR Quinlan; YM Janssen; Cynthia R Timblin; J P Marsh; Nicholas H Heintz; Douglas J Taatjes; Pamela M Vacek; Susan Jaken; Brooke T Mossman
Inhibition of protein kinase C prevents asbestos-induced c-fos and c-jun proto-oncogene expression in mesothelial cells.
Cancer research 1997;57(15):3101-5.
1997: H Fung; Yoke W Kow; Bennett Van Houten; Brooke T Mossman
Patterns of 8-hydroxydeoxyguanosine formation in DNA and indications of oxidative stress in rat and human pleural mesothelial cells after exposure to crocidolite asbestos.
Carcinogenesis 1997;18(4):825-32.
1996: CL Zanella; J Posada; TR Tritton; Brooke T Mossman
Asbestos causes stimulation of the extracellular signal-regulated kinase 1 mitogen-activated protein kinase cascade after phosphorylation of the epidermal growth factor receptor.
Cancer research 1996;56(23):5334-8.
1996: M D Treadwell; Brooke T Mossman; Aaron Barchowsky
Increased neutrophil adherence to endothelial cells exposed to asbestos.
Toxicology and applied pharmacology 1996;139(1):62-70.
1996: K A BéruBé; TR Quinlan; H Fung; J Magae; Pamela M Vacek; Douglas J Taatjes; Brooke T Mossman
Apoptosis is observed in mesothelial cells after exposure to crocidolite asbestos.
American journal of respiratory cell and molecular biology 1996;15(1):141-7.
1996: K A BéruBé; TR Quinlan; G Moulton; David Hemenway; P O'Shaughnessy; Pamela M Vacek; Brooke T Mossman
Comparative proliferative and histopathologic changes in rat lungs after inhalation of chrysotile or crocidolite asbestos.
Toxicology and applied pharmacology 1996;137(1):67-74.
1996: Brooke T Mossman; P Surinrut; B T Brinton; J P Marsh; Nicholas H Heintz; B Lindau-Shepard; J B Shaffer
Transfection of a manganese-containing superoxide dismutase gene into hamster tracheal epithelial cells ameliorates asbestos-mediated cytotoxicity.
Free radical biology & medicine 1996;21(2):125-31.
1996: Brooke T Mossman; D W Kamp; S A Weitzman
Mechanisms of carcinogenesis and clinical features of asbestos-associated cancers.
Cancer investigation 1996;14(5):466-80.
1995: Kevin E Driscoll; DG Hassenbein; Janet M Carter; Steven Kunkel; TR Quinlan; Brooke T Mossman
TNF alpha and increased chemokine expression in rat lung after particle exposure.
Toxicology letters 1995;82-83():483-9.
1995: TR Quinlan; K A BéruBé; J P Marsh; YM Janssen; P Taishi; KO Leslie; David Hemenway; P T O'Shaughnessy; Pamela M Vacek; Brooke T Mossman
Patterns of inflammation, cell proliferation, and related gene expression in lung after inhalation of chrysotile asbestos.
The American journal of pathology 1995;147(3):728-39.
1995: YM Janssen; Aaron Barchowsky; M Treadwell; Kevin E Driscoll; Brooke T Mossman
Asbestos induces nuclear factor kappa B (NF-kappa B) DNA-binding activity and NF-kappa B-dependent gene expression in tracheal epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(18):8458-62.
1995: Cynthia R Timblin; Y W Janssen; Brooke T Mossman
Transcriptional activation of the proto-oncogene c-jun by asbestos and H2O2 is directly related to increased proliferation and transformation of tracheal epithelial cells.
Cancer research 1995;55(13):2723-6.
1995: YM Janssen; Nicholas H Heintz; Brooke T Mossman
Induction of c-fos and c-jun proto-oncogene expression by asbestos is ameliorated by N-acetyl-L-cysteine in mesothelial cells.
Cancer research 1995;55(10):2085-9.
1994: TR Quinlan; J P Marsh; YM Janssen; P A Borm; Brooke T Mossman
Oxygen radicals and asbestos-mediated disease.
Environmental health perspectives 1994;102 Suppl 10():107-10.
1994: YM Janssen; Nicholas H Heintz; J P Marsh; Paul J A Borm; Brooke T Mossman
Induction of c-fos and c-jun proto-oncogenes in target cells of the lung and pleura by carcinogenic fibers.
American journal of respiratory cell and molecular biology 1994;11(5):522-30.
1994: TR Quinlan; J P Marsh; YM Janssen; KO Leslie; David Hemenway; Pamela M Vacek; Brooke T Mossman
Dose-responsive increases in pulmonary fibrosis after inhalation of asbestos.
American journal of respiratory and critical care medicine 1994;150(1):200-6.
1994: TR Quinlan; S Spivack; Brooke T Mossman
Regulation of antioxidant enzymes in lung after oxidant injury.
Environmental health perspectives 1994;102 Suppl 2():79-87.
1994: YM Janssen; J P Marsh; M P Absher; Edward Gabrielson; Paul J A Borm; Kevin E Driscoll; Brooke T Mossman
Oxidant stress responses in human pleural mesothelial cells exposed to asbestos.
American journal of respiratory and critical care medicine 1994;149(3 Pt 1):795-802.
1994: YM Janssen; J P Marsh; Kevin E Driscoll; Paul J A Borm; Günter Oberdörster; Brooke T Mossman
Increased expression of manganese-containing superoxide dismutase in rat lungs after inhalation of inflammatory and fibrogenic minerals.
Free radical biology & medicine 1994;16(3):315-22.
1994: J P Marsh; Brooke T Mossman; Kevin E Driscoll; R F Schins; Paul J A Borm
Effects of Aramid, a high strength synthetic fiber, on respiratory cells in vitro.
Drug and chemical toxicology 1994;17(2):75-92.
1993: YM Janssen; Bennett Van Houten; Paul J A Borm; Brooke T Mossman
Cell and tissue responses to oxidative damage.
Laboratory investigation; a journal of technical methods and pathology 1993;69(3):261-74.
1993: Nicholas H Heintz; YM Janssen; Brooke T Mossman
Persistent induction of c-fos and c-jun expression by asbestos.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3299-303.
1992: J A Holley; YM Janssen; Brooke T Mossman; Douglas J Taatjes
Increased manganese superoxide dismutase protein in type II epithelial cells of rat lungs after inhalation of crocidolite asbestos or cristobalite silica.
The American journal of pathology 1992;141(2):475-85.
1992: YM Janssen; J P Marsh; M P Absher; David Hemenway; Pamela M Vacek; KO Leslie; Paul J A Borm; Brooke T Mossman
Expression of antioxidant enzymes in rat lungs after inhalation of asbestos or silica.
The Journal of biological chemistry 1992;267(15):10625-30.
1991: S Shull; Nicholas H Heintz; Muthu Periasamy; M Manohar; YM Janssen; J P Marsh; Brooke T Mossman
Differential regulation of antioxidant enzymes in response to oxidants.
The Journal of biological chemistry 1991;266(36):24398-403.
1991: M Perderiset; J P Marsh; Brooke T Mossman
Activation of protein kinase C by crocidolite asbestos in hamster tracheal epithelial cells.
Carcinogenesis 1991;12(8):1499-502.
1991: S W Edmondson; Brooke T Mossman
Alterations in keratin expression in hamster tracheal epithelial cells exposed to benzo[a]pyrene.
Carcinogenesis 1991;12(4):679-84.
1991: J P Marsh; Brooke T Mossman
Role of asbestos and active oxygen species in activation and expression of ornithine decarboxylase in hamster tracheal epithelial cells.
Cancer research 1991;51(1):167-73.
1991: Brooke T Mossman; YM Janssen; J P Marsh; A Sesko; MA Shatos; J Doherty; K B Adler; David Hemenway; Ruth M Mickey
Development and characterization of a rapid-onset rodent inhalation model of asbestosis for disease prevention.
Toxicologic pathology 1991;19(4 Pt 1):412-8.
1991: J M Petruska; KO Leslie; Brooke T Mossman
Enhanced lipid peroxidation in lung lavage of rats after inhalation of asbestos.
Free radical biology & medicine 1991;11(4):425-32.
1990: A Sesko; M Cabot; Brooke T Mossman
Hydrolysis of inositol phospholipids precedes cellular proliferation in asbestos-stimulated tracheobronchial epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(19):7385-9.
1990: Brooke T Mossman
In vitro studies on the biologic effects of fibers: correlation with in vivo bioassays.
Environmental health perspectives 1990;88():319-22.
1990: Brooke T Mossman; J P Marsh; A Sesko; S Hill; MA Shatos; J Doherty; J Petruska; K B Adler; David Hemenway; Ruth M Mickey
Inhibition of lung injury, inflammation, and interstitial pulmonary fibrosis by polyethylene glycol-conjugated catalase in a rapid inhalation model of asbestosis.
The American review of respiratory disease 1990;141(5 Pt 1):1266-71.
1990: J M Petruska; J Marsh; M Bergeron; Brooke T Mossman
Brief inhalation of asbestos compromises superoxide production in cells from bronchoalveolar lavage.
American journal of respiratory cell and molecular biology 1990;2(2):129-36.
1990: Brooke T Mossman; J Bignon; M Corn; A Seaton; J B Gee
Asbestos: scientific developments and implications for public policy.
Science (New York, N.Y.) 1990;247(4940):294-301.
1990: J M Petruska; S H Wong; F W Sunderman; Brooke T Mossman
Detection of lipid peroxidation in lung and in bronchoalveolar lavage cells and fluid.
Free radical biology & medicine 1990;9(1):51-8.
1990: Brooke T Mossman; A M Sesko
In vitro assays to predict the pathogenicity of mineral fibers.
Toxicology 1990;60(1-2):53-61.
1990: YM Janssen; J P Marsh; M Absher; Paul J A Borm; Brooke T Mossman
Increases in endogenous antioxidant enzymes during asbestos inhalation in rats.
Free radical research communications 1990;11(1-3):53-8.
1990: S W Edmondson; Reen Wu; Brooke T Mossman
Regulation of differentiation and keratin protein expression by vitamin A in primary cultures of hamster tracheal epithelial cells.
Journal of cellular physiology 1990;142(1):21-30.
1989: Brooke T Mossman; J B Gee
Asbestos-related diseases.
The New England journal of medicine 1989;320(26):1721-30.
1989: A M Sesko; Brooke T Mossman
Sensitivity of hamster tracheal epithelial cells to asbestiform minerals modulated by serum and by transforming growth factor beta 1.
Cancer research 1989;49(10):2743-9.
1989: Brooke T Mossman; J P Marsh
Evidence supporting a role for active oxygen species in asbestos-induced toxicity and lung disease.
Environmental health perspectives 1989;81():91-4.
1989: G Cameron; C D Woodworth; S Edmondson; Brooke T Mossman
Mechanisms of asbestos-induced squamous metaplasia in tracheobronchial epithelial cells.
Environmental health perspectives 1989;80():101-8.
1989: Brooke T Mossman; K Hansen; J P Marsh; M E Brew; S Hill; M Bergeron; J Petruska
Mechanisms of fibre-induced superoxide release from alveolar macrophages and induction of superoxide dismutase in the lungs of rats inhaling crocidolite.
IARC scientific publications 1989;(90):81-92.
1988: J P Marsh; Brooke T Mossman
Mechanisms of induction of ornithine decarboxylase activity in tracheal epithelial cells by asbestiform minerals.
Cancer research 1988;48(3):709-14.
1987: MA Shatos; J M Doherty; J P Marsh; Brooke T Mossman
Prevention of asbestos-induced cell death in rat lung fibroblasts and alveolar macrophages by scavengers of active oxygen species.
Environmental research 1987;44(1):103-16.
1987: Brooke T Mossman; J P Marsh; MA Shatos; J Doherty; R Gilbert; S Hill
Implication of active oxygen species as second messengers of asbestos toxicity.
Drug and chemical toxicology 1987;10(1-2):157-80.
1986: Brooke T Mossman; R Gilbert; J Doherty; MA Shatos; J Marsh; K Cutroneo
Cellular and molecular mechanisms of asbestosis.
Chest 1986;89(3 Suppl):160S-161S.
1986: Brooke T Mossman; J P Marsh; MA Shatos
Alteration of superoxide dismutase activity in tracheal epithelial cells by asbestos and inhibition of cytotoxicity by antioxidants.
Laboratory investigation; a journal of technical methods and pathology 1986;54(2):204-12.
1986: Brooke T Mossman; J P Marsh; D Hardwick; R Gilbert; S Hill; A Sesko; MA Shatos; J Doherty; A Weller; M Bergeron
Approaches to prevention of asbestos-induced lung disease using polyethylene glycol (PEG)-conjugated catalase.
Journal of free radicals in biology & medicine 1986;2(5-6):335-8.