John Mountz

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Xu X; Hsu H-C; Chen J; Grizzle W E; Chatham W W; Stockard C R; Wu Q; Yang P A; Holers V M; Mountz J D
Increased expression of activation-induced cytidine deaminase is associated with anti-CCP and rheumatoid factor in rheumatoid arthritis.
Ren C; Kumar S; Chanda D; Kallman L; Chen J; Mountz J D; Ponnazhagan S
Cancer gene therapy using mesenchymal stem cells expressing interferon-beta in a mouse prostate cancer lung metastasis model.
Ren Changchun; Kumar Sanjay; Chanda Diptiman; Chen Jian; Mountz John D; Ponnazhagan Selvarangan
Therapeutic potential of mesenchymal stem cells producing interferon-alpha in a mouse melanoma lung metastasis model.

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All Publications

2009: Xu X; Hsu H-C; Chen J; Grizzle W E; Chatham W W; Stockard C R; Wu Q; Yang P A; Holers V M; Mountz J D
Increased expression of activation-induced cytidine deaminase is associated with anti-CCP and rheumatoid factor in rheumatoid arthritis.
Scandinavian journal of immunology 2009;70(3):309-16.
2008: Ren C; Kumar S; Chanda D; Kallman L; Chen J; Mountz J D; Ponnazhagan S
Cancer gene therapy using mesenchymal stem cells expressing interferon-beta in a mouse prostate cancer lung metastasis model.
Gene therapy 2008;15(21):1446-53.
2008: Ren Changchun; Kumar Sanjay; Chanda Diptiman; Chen Jian; Mountz John D; Ponnazhagan Selvarangan
Therapeutic potential of mesenchymal stem cells producing interferon-alpha in a mouse melanoma lung metastasis model.
Stem cells (Dayton, Ohio) 2008;26(9):2332-8.
2008: Chen Jian; Wang John; Li Jun; Wu Qi; Chu Lim Fei; Yang Pingar; Hsu Hui-Chen; Curiel David T; Mountz John D
Enhancement of cytotoxic T-lymphocyte response in aged mice by a novel treatment with recombinant AdIL-12 and wild-type adenovirus in rapid succession.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(8):1500-6.
2008: Hsu Hui-Chen; Yang PingAr; Wang John; Wu Qi; Myers Riley; Chen Jian; Yi John; Guentert Tanja; Tousson Albert; Stanus Andrea L; Le Thuc-vy L; Lorenz Robin G; Xu Hui; Kolls Jay K; Carter Robert H; Chaplin David D; Williams Robert W; Mountz John D
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice.
Nature immunology 2008;9(2):166-75.
2008: Matthews Qiana L; Yang PingAr; Wu Qi; Belousova Natalya; Rivera Angel A; Stoff-Khalili Mariam A; Waehler Reinhard; Hsu Hui-Chen; Li Zan; Li Jing; Mountz John D; Wu Hongju; Curiel David T
Optimization of capsid-incorporated antigens for a novel adenovirus vaccine approach.
Virology journal 2008;5():98.
2007: Grizzle William E; Xu Xin; Zhang Shuangqin; Stockard Cecil R; Liu Cunren; Yu Shaohua; Wang Jianhua; Mountz John D; Zhang Huang-Ge
Age-related increase of tumor susceptibility is associated with myeloid-derived suppressor cell mediated suppression of T cell cytotoxicity in recombinant inbred BXD12 mice.
Mechanisms of ageing and development 2007;128(11-12):672-80.
2007: Hsu Hui-Chen; Wu Yalei; Yang Pingar; Wu Qi; Job Godwin; Chen Jian; Wang John; Accavitti-Loper Mary Ann V; Grizzle William E; Carter Robert H; Mountz John D
Overexpression of activation-induced cytidine deaminase in B cells is associated with production of highly pathogenic autoantibodies.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(8):5357-65.
2007: Hsu Hui-Chen; Lu Lu; Yi Nengjun; Van Zant Gary; Williams Robert W; Mountz John D
Quantitative trait locus (QTL) mapping in aging systems.
Methods in molecular biology (Clifton, N.J.) 2007;371():321-48.
2006: Musani Solomon K; Zhang Huang-Ge; Hsu Hui-Chen; Yi Nengjun; Gorman Bernard S; Allison David B; Mountz John D
Principal component analysis of quantitative trait loci for immune response to adenovirus in mice.
Hereditas 2006;143(2006):189-97.
2006: Wang X; Hsu H-C; Wang Y; Edwards C K; Yang P; Wu Q; Mountz J D
Phenotype of genetically regulated thymic involution in young BXD RI strains of mice.
Scandinavian journal of immunology 2006;64(3):287-94.
2006: Chen Jian; Hsu Hui-Chen; Zajac Allan J; Wu Qi; Yang Pingar; Xu Xin; McPherson Sylvia A; Li Jun; Curiel David T; Mountz John D
In vivo analysis of adenovirus-specific cytotoxic T lymphocyte response in mice deficient in CD28, fas ligand, and perforin.
Human gene therapy 2006;17(6):669-82.
2006: Hsu Hui-Chen; Scott Donald K; Zhang Pili; Zhou Juling; Yang PingAr; Wu Qi; Schroeder Harry W; Gerald Lynn B; Ravussin Eric; Jazwinski S Michal; Mountz John D;
CD8 T-cell immune phenotype of successful aging.
Mechanisms of ageing and development 2006;127(3):231-9.
2006: Chen Jian; Wu Qi; Yang Pingar; Hsu Hui-Chen; Mountz John D
Determination of specific CD4 and CD8 T cell epitopes after AAV2- and AAV8-hF.IX gene therapy.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(2):260-9.
2006: Hsu Hui-Chen; Zhou Tong; Kim Helen; Barnes Stephen; Yang PingAr; Wu Qi; Zhou Juling; Freeman Bruce A; Luo Ming; Mountz John D
Production of a novel class of polyreactive pathogenic autoantibodies in BXD2 mice causes glomerulonephritis and arthritis.
Arthritis and rheumatism 2006;54(1):343-55.
2006: Hsu Hui-Chen; Wu Yalei; Mountz John D
Tumor necrosis factor ligand-receptor superfamily and arthritis.
Current directions in autoimmunity 2006;9():37-54.
2005: Wu Yalei; Liu Jianzhong; Feng Xu; Yang Pingar; Xu Xin; Hsu Hui-Chen; Mountz John D
Synovial fibroblasts promote osteoclast formation by RANKL in a novel model of spontaneous erosive arthritis.
Arthritis and rheumatism 2005;52(10):3257-68.
2005: Yang Xinwen; Wang Jianhua; Liu Cunren; Grizzle William E; Yu Shaohua; Zhang Shuangqin; Barnes Stephen; Koopman William J; Mountz John D; Kimberly Robert P; Zhang Huang-Ge
Cleavage of p53-vimentin complex enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of rheumatoid arthritis synovial fibroblasts.
The American journal of pathology 2005;167(3):705-19.
2005: Chen J; Zajac A J; McPherson S A; Hsu H-C; Yang P; Wu Q; Xu X; Wang X; Fujihashi K; Curiel D T; Mountz J D
Primary adenovirus-specific cytotoxic T lymphocyte response occurs after viral clearance and liver enzyme elevation.
Gene therapy 2005;12(13):1079-88.
2005: Zhang Huang-Ge; High Katherine A; Wu Qi; Yang PingAr; Schlachterman Alex; Yu Shaohua; Yi Nengjun; Hsu Hui-Chen; Mountz John D
Genetic analysis of the antibody response to AAV2 and factor IX.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(6):866-74.
2005: Hsu Hui-Chen; Scott Donald K; Mountz John D
Impaired apoptosis and immune senescence - cause or effect?
Immunological reviews 2005;205():130-46.
2005: Mountz J D; Yang P; Wu Q; Zhou J; Tousson A; Fitzgerald A; Allen J; Wang X; Cartner S; Grizzle W E; Yi N; Lu L; Williams R W; Hsu H-C
Genetic segregation of spontaneous erosive arthritis and generalized autoimmune disease in the BXD2 recombinant inbred strain of mice.
Scandinavian journal of immunology 2005;61(2):128-38.
2005: Hsu Hui-Chen; Li Lina; Zhang Huang-Ge; Mountz John D
Genetic regulation of thymic involution.
Mechanisms of ageing and development 2005;126(1):87-97.
2004: Hsu Hui-Chen; Zhou Tong; Mountz John D
Nur77 family of nuclear hormone receptors.
Current drug targets. Inflammation and allergy 2004;3(4):413-23.
2004: Xu X; Zhang H-G; Liu Z-Y; Wu Q; Yang P-A; Sun S-H; Chen J; Hsu H-C; Mountz J D
Defective clearance of adenovirus in IRF-1 mice associated with defects in NK and T cells but not macrophages.
Scandinavian journal of immunology 2004;60(1-2):89-99.
2004: Zhang Huang-Ge; Wang Jianhua; Yang Xinwen; Hsu Hui-Chen; Mountz John D
Regulation of apoptosis proteins in cancer cells by ubiquitin.
Oncogene 2004;23(11):2009-15.
2004: Li Lina; Hsu Hui-Chen; Stockard Cecil R; Yang PingAr; Zhou Juling; Wu Qi; Grizzle William E; Mountz John D
IL-12 inhibits thymic involution by enhancing IL-7- and IL-2-induced thymocyte proliferation.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(5):2909-16.
2004: Zhang Huang-Ge; Hyde Karren; Page Grier P; Brand Jacob P L; Zhou Juling; Yu Shaohua; Allison David B; Hsu Hui-Chen; Mountz John D
Novel tumor necrosis factor alpha-regulated genes in rheumatoid arthritis.
Arthritis and rheumatism 2004;50(2):420-31.
2004: Zhang H-G; Hsu H-C; Yang P-A; Yang X; Wu Q; Liu Z; Yi N; Mountz J D
Identification of multiple genetic loci that regulate adenovirus gene therapy.
Gene therapy 2004;11(1):4-14.
2004: Hoves Sabine; Krause Stefan W; Herfarth Hans; Halbritter Dagmar; Zhang Huang-Ge; Mountz John D; Schölmerich Jürgen; Fleck Martin
Elimination of activated but not resting primary human CD4+ and CD8+ T cells by Fas ligand (FasL/CD95L)-expressing Killer-dendritic cells.
Immunobiology 2004;208(5):463-75.
2003: Liu Zhongyu; Xu Xin; Hsu Hui-Chen; Tousson Albert; Yang Ping-Ar; Wu Qi; Liu Cunren; Yu Shaohua; Zhang Huang-Ge; Mountz John D
CII-DC-AdTRAIL cell gene therapy inhibits infiltration of CII-reactive T cells and CII-induced arthritis.
The Journal of clinical investigation 2003;112(9):1332-41.
2003: Hsu H-C; Zhang H-G; Li L; Yi N; Yang P-A; Wu Q; Zhou J; Sun S; Xu X; Yang X; Lu L; Van Zant G; Williams R W; Allison D B; Mountz J D
Age-related thymic involution in C57BL/6J x DBA/2J recombinant-inbred mice maps to mouse chromosomes 9 and 10.
Genes and immunity 2003;4(6):402-10.
2003: Hoves Sabine; Krause Stefan W; Halbritter Dagmar; Zhang Huang-Ge; Mountz John D; Schölmerich Jürgen; Fleck Martin
Mature but not immature Fas ligand (CD95L)-transduced human monocyte-derived dendritic cells are protected from Fas-mediated apoptosis and can be used as killer APC.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(11):5406-13.
2003: Li L; Hsu H-C; Grizzle W E; Stockard C R; Ho K-J; Lott P; Yang P-A; Zhang H-G; Mountz J D;
Cellular mechanism of thymic involution.
Scandinavian journal of immunology 2003;57(5):410-22.
2003: Hsu Hui-Chen; Mountz John D
Origin of late-onset autoimmune disease.
Immunology and allergy clinics of North America 2003;23(1):65-82, vi.
2002: Zhang Huang-Ge; Xie Jinfu; Dmitriev Igor; Kashentseva Elena; Curiel David T; Hsu Hui-Chen; Mountz John D
Addition of six-His-tagged peptide to the C terminus of adeno-associated virus VP3 does not affect viral tropism or production.
Journal of virology 2002;76(23):12023-31.
2002: Grizzle William E; Mountz John D; Yang Ping-Ar; Xu Xin; Sun Sheher; Van Zant Gary E; Williams Robert W; Hsu Hui-Chen; Zhang Huang-Ge
BXD recombinant inbred mice represent a novel T cell-mediated immune response tumor model.
International journal of cancer. Journal international du cancer 2002;101(3):270-9.
2002: Matsuki Y; Zhang H G; Hsu H C; Yang P A; Zhou T; Dodd C H; Cecconi F; Gruss P; Tadakuma T; Mountz J D
Different role of Apaf-1 in positive selection, negative selection and death by neglect in foetal thymic organ culture.
Scandinavian journal of immunology 2002;56(2):174-84.
2002: Matsuki Y; Li L; Hsu H-C; Yang P A; Zheng R; Edwards C K; Chaudry I H; Zhang H-G; Mountz J D
Soluble Fas gene therapy protects against Fas-mediated apoptosis of hepatocytes but not the lethal effects of Fas-induced TNF-alpha production by Kupffer cells.
Cell death and differentiation 2002;9(6):626-35.
2002: Zhang Huang-Ge; Xie Jinfu; Xu Liang; Yang Pingar; Xu Xin; Sun Sheher; Wang Yongming; Curiel David T; Hsu Hui-Chen; Mountz John D
Hepatic DR5 induces apoptosis and limits adenovirus gene therapy product expression in the liver.
Journal of virology 2002;76(11):5692-700.
2002: Hsu Hui-Chen; Mountz John D; Williams Robert W; Shelton Brent J; Yang Ping-Ar; Matsuki Yasunori; Xu Xin; Dodd Christopher H; Li Lina; Geiger Hartmut; Zhang Huang-Ge; Van Zant Gary
Age-related change in thymic T-cell development is associated with genetic loci on mouse chromosomes 1, 3, and 11.
Mechanisms of ageing and development 2002;123(8):1145-58.
2002: Mountz John D; Zant Gary Van; Allison David B; Zhang Huang-Ge; Hsu Hui-Chen
Beneficial influences of systemic cooperation and sociological behavior on longevity.
Mechanisms of ageing and development 2002;123(8):963-73.
2002: Neumann Elena; Barnum Scott R; Tarner Ingo H; Echols Josh; Fleck Martin; Judex Martin; Kullmann Frank; Mountz John D; Schölmerich Jürgen; Gay Steffen; Müller-Ladner Ulf
Local production of complement proteins in rheumatoid arthritis synovium.
Arthritis and rheumatism 2002;46(4):934-45.
2002: Mountz John D; Hsu Hui-Chen; Wu Qi; Liu Hong-Gang; Zhang Huang-Ge; Mountz James M
Molecular imaging: new applications for biochemistry.
Journal of cellular biochemistry. Supplement 2002;39():162-71.
2002: Zhou Tong; Mountz John D; Kimberly Robert P
Immunobiology of tumor necrosis factor receptor superfamily.
Immunologic research 2002;26(1-3):323-36.
2002: Zhan Huang-Ge; Mountz John D; Fleck Martin; Zhou Tong; Hsu Hui-Chen
Specific deletion of autoreactive T cells by adenovirus-transfected, Fas ligand-producing antigen-presenting cells.
Immunologic research 2002;26(1-3):235-46.
2001: Hsu H C; Shi J; Yang P; Xu X; Dodd C; Matsuki Y; Zhang H G; Mountz J D
Activated CD8(+) T cells from aged mice exhibit decreased activation-induced cell death.
Mechanisms of ageing and development 2001;122(15):1663-84.
2001: Dodd C H; Hsu H C; Chu W J; Yang P; Zhang H G; Mountz J D; Zinn K; Forder J; Josephson L; Weissleder R; Mountz J M; Mountz J D
Normal T-cell response and in vivo magnetic resonance imaging of T cells loaded with HIV transactivator-peptide-derived superparamagnetic nanoparticles.
Journal of immunological methods 2001;256(1-2):89-105.
2001: Dodd C H; Hsu H C; Chu W J; Yang P; Zhang H G; Mountz J D; Zinn K; Forder J; Josephson L; Weissleder R; Mountz J M; Mountz J D
Normal T-cell response and in vivo magnetic resonance imaging of T cells loaded with HIV transactivator-peptide-derived superparamagnetic nanoparticles.
Journal of immunological methods 2001;256(1-2):89-105.
2001: Hsu H C; Zhang H G; Song G G; Xie J; Liu D; Yang P A; Fleck M; Wintersberger W; Zhou T; Edwards C K; Mountz J D
Defective Fas ligand-mediated apoptosis predisposes to development of a chronic erosive arthritis subsequent to Mycoplasma pulmonis infection.
Arthritis and rheumatism 2001;44(9):2146-59.
2001: Zhang H G; Wang Y; Xie J F; Liang X; Liu D; Yang P; Hsu H C; Ray R B; Mountz J D
Regulation of tumor necrosis factor alpha-mediated apoptosis of rheumatoid arthritis synovial fibroblasts by the protein kinase Akt.
Arthritis and rheumatism 2001;44(7):1555-67.
2001: Hoves S; Niller H H; Krause S W; Straub R; Glück T; Mountz J D; Schölmerich J; Fleck M
Decreased T cell stimulatory capacity of monocyte-derived human macrophages following herpes simplex virus type 1 infection.
Scandinavian journal of immunology 2001;54(1-2):93-9.
2001: Mountz J D; Van Zant G E; Zhang H G; Grizzle W E; Ahmed R; Williams R W; Hsu H C
Genetic dissection of age-related changes of immune function in mice.
Scandinavian journal of immunology 2001;54(1-2):10-20.
2001: Zhang H G; Wang Y M; Xie J F; Liang X; Hsu H C; Zhang X; Douglas J; Curiel D T; Mountz J D
Recombinant adenovirus expressing adeno-associated virus cap and rep proteins supports production of high-titer recombinant adeno-associated virus.
Gene therapy 2001;8(9):704-12.
2001: Fleck M; Zhang H G; Kern E R; Hsu H C; Müller-Ladner U; Mountz J D
Treatment of chronic sialadenitis in a murine model of Sjögren's syndrome by local fasL gene transfer.
Arthritis and rheumatism 2001;44(4):964-73.
2001: Hsu H C; Zhou T; Shi J; Yang P A; Liu D; Zhang H G; Bluethmann H; Mountz J D
Aged mice exhibit in vivo defective peripheral clonal deletion of D(b)/H-Y reactive CD8(+) T cells.
Mechanisms of ageing and development 2001;122(3):305-26.
2001: Hsu H C; Matsuki Y; Zhang H G; Zhou T; Mountz J D
The Fas signaling connection between autoimmunity and embryonic lethality.
Journal of clinical immunology 2001;21(1):1-14.
2001: Hsu H C; Shultz L D; Su X; Shi J; Yang P A; Relyea M J; Zhang H G; Mountz J D
Mutation of the hematopoietic cell phosphatase (Hcph) gene is associated with resistance to gamma-irradiation-induced apoptosis in Src homology protein tyrosine phosphatase (SHP)-1-deficient "motheaten" mutant mice.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(2):772-80.
2001: Mountz J D; Zhang H G
Regulation of apoptosis of synovial fibroblasts.
Current directions in autoimmunity 2001;3():216-39.
2000: Zhang H G; Xie J; Yang P; Wang Y; Xu L; Liu D; Hsu H C; Zhou T; Edwards C K; Mountz J D
Adeno-associated virus production of soluble tumor necrosis factor receptor neutralizes tumor necrosis factor alpha and reduces arthritis.
Human gene therapy 2000;11(17):2431-42.
2000: Zhang H G; Huang N; Liu D; Bilbao L; Zhang X; Yang P; Zhou T; Curiel D T; Mountz J D
Gene therapy that inhibits nuclear translocation of nuclear factor kappaB results in tumor necrosis factor alpha-induced apoptosis of human synovial fibroblasts.
Arthritis and rheumatism 2000;43(5):1094-105.
2000: Zhang H G; Fleck M; Kern E R; Liu D; Wang Y; Hsu H C; Yang P; Wang Z; Curiel D T; Zhou T; Mountz J D
Antigen presenting cells expressing Fas ligand down-modulate chronic inflammatory disease in Fas ligand-deficient mice.
The Journal of clinical investigation 2000;105(6):813-21.
1999: Zinn K R; Chaudhuri T R; Smyth C A; Wu Q; Liu H G; Fleck M; Mountz J D; Mountz J M
Specific targeting of activated endothelium in rat adjuvant arthritis with a 99mTc-radiolabeled E-selectin-binding peptide.
Arthritis and rheumatism 1999;42(4):641-9.
1999: Bilbao G; Zhang H; Contreras J L; Zhou T; Feng M; Saito I; Mountz J D; Curiel D T
Construction of a recombinant adenovirus vector encoding Fas ligand with a CRE/Loxp inducible system.
Transplantation proceedings 1999;31(1-2):792-3.
1999: Zhang H G; Su X; Liu D; Liu W; Yang P; Wang Z; Edwards C K; Bluethmann H; Mountz J D; Zhou T
Induction of specific T cell tolerance by Fas ligand-expressing antigen-presenting cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(3):1423-30.
1999: Hsu H C; Mountz J D; Zhou T
Regulation of Fas-mediated apoptosis in CD2-fas transgenic mice.
International reviews of immunology 1999;18(4):309-27.
1999: Fleck M; Mountz J D; Hsu H C; Wu J; Edwards C K; Kern E R
Herpes simplex virus type 2 infection induced apoptosis in peritoneal macrophages independent of Fas and tumor necrosis factor-receptor signaling.
Viral immunology 1999;12(3):263-75.
1998: Fleck M; Kern E R; Zhou T; Lang B; Mountz J D
Murine cytomegalovirus induces a Sjögren's syndrome-like disease in C57Bl/6-lpr/lpr mice.
Arthritis and rheumatism 1998;41(12):2175-84.
1998: Zhang H G; Liu D; Heike Y; Yang P; Wang Z; Wang X; Curiel D T; Zhou T; Mountz J D
Induction of specific T-cell tolerance by adenovirus-transfected, Fas ligand-producing antigen presenting cells.
Nature biotechnology 1998;16(11):1045-9.
1998: San Pedro E C; Mountz J M; Mountz J D; Liu H G; Katholi C R; Deutsch G
Familial painful restless legs syndrome correlates with pain dependent variation of blood flow to the caudate, thalamus, and anterior cingulate gyrus.
The Journal of rheumatology 1998;25(11):2270-5.
1998: Fleck M; Kern E R; Zhou T; Podlech J; Wintersberger W; Edwards C K; Mountz J D
Apoptosis mediated by Fas but not tumor necrosis factor receptor 1 prevents chronic disease in mice infected with murine cytomegalovirus.
The Journal of clinical investigation 1998;102(7):1431-43.
1998: Zhang H G; Zhou T; Yang P; Edwards C K; Curiel D T; Mountz J D
Inhibition of tumor necrosis factor alpha decreases inflammation and prolongs adenovirus gene expression in lung and liver.
Human gene therapy 1998;9(13):1875-84.
1998: Zinn K R; Douglas J T; Smyth C A; Liu H G; Wu Q; Krasnykh V N; Mountz J D; Curiel D T; Mountz J M
Imaging and tissue biodistribution of 99mTc-labeled adenovirus knob (serotype 5).
Gene therapy 1998;5(6):798-808.
1998: Wu J; He J; Mountz J D
Effect of age and apoptosis on the mouse homologue of the huWRN gene.
Mechanisms of ageing and development 1998;103(1):27-44.
1998: Su X; Cheng J; Liu W; Liu C; Wang Z; Yang P; Zhou T; Mountz J D
Autocrine and paracrine apoptosis are mediated by differential regulation of Fas ligand activity in two distinct Jurkat T cell populations.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(11):5288-93.
1998: Fleck M; Zhou T; Tatsuta T; Yang P; Wang Z; Mountz J D
Fas/Fas ligand signaling during gestational T cell development.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(8):3766-75.
1998: Zhang H G; Bilbao G; Zhou T; Contreras J L; Gómez-Navarro J; Feng M; Saito I; Mountz J D; Curiel D T
Application of a Fas ligand encoding a recombinant adenovirus vector for prolongation of transgene expression.
Journal of virology 1998;72(3):2483-90.
1998: Su X; Zhou T; Yang P; Edwards C K; Mountz J D
Reduction of arthritis and pneumonitis in motheaten mice by soluble tumor necrosis factor receptor.
Arthritis and rheumatism 1998;41(1):139-49.
1997: Mountz J D; Wu J; Zhou T; Hsu H C
Cell death and longevity: implications of Fas-mediated apoptosis in T-cell senescence.
Immunological reviews 1997;160():19-30.
1997: Mountz J D; Hsu H C
Clinical features associated with correction of T-cell senescence: increased acute-phase response, amyloidosis and arthritis.
Developmental and comparative immunology 1997;21(6):509-23.
1997: Cheng J; Liu C; Yang P; Zhou T; Mountz J D
Increased lymphocyte apoptosis in Fas ligand transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(2):674-84.
1997: Hsu H C; Zhou T; Yang P A; Herrera G A; Mountz J D
Increased acute-phase response and renal amyloidosis in aged CD2-fas-transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(12):5988-96.
1997: Herndon F J; Hsu H C; Mountz J D
Increased apoptosis of CD45RO- T cells with aging.
Mechanisms of ageing and development 1997;94(1-3):123-34.
1997: Zhou T; Fleck M; Müeller-Ladner U; Yang P; Wang Z; Gay S; Matsumoto S; Mountz J D
Kinetics of Fas-induced apoptosis in thymic organ culture.
Journal of clinical immunology 1997;17(1):74-84.
1996: Mountz J D; Zhou T; Su X; Cheng J; Pierson M; Bluethmann H; Edwards C K
Autoimmune disease results from multiple interactive defects in apoptosis induction molecules and signaling pathways.
Behring Institute Mitteilungen 1996;(97):200-19.
1996: Wu J; Wilson J; He J; Xiang L; Schur P H; Mountz J D
Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease.
The Journal of clinical investigation 1996;98(5):1107-13.
1996: Edwards C K; Zhou T; Zhang J; Baker T J; De M; Long R E; Borcherding D R; Bowlin T L; Bluethmann H; Mountz J D
Inhibition of superantigen-induced proinflammatory cytokine production and inflammatory arthritis in MRL-lpr/lpr mice by a transcriptional inhibitor of TNF-alpha.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(4):1758-72.
1996: Su X; Zhou T; Yang P A; Wang Z; Mountz J D
Hematopoietic cell protein-tyrosine phosphatase-deficient motheaten mice exhibit T cell apoptosis defect.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(11):4198-208.
1996: Zhou T; Cheng J; Yang P; Wang Z; Liu C; Su X; Bluethmann H; Mountz J D
Inhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self-reactive T cells.
The Journal of experimental medicine 1996;183(4):1879-92.
1996: Zhou T; Edwards C K; Yang P; Wang Z; Bluethmann H; Mountz J D
Greatly accelerated lymphadenopathy and autoimmune disease in lpr mice lacking tumor necrosis factor receptor I.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(8):2661-5.
1996: Mountz J D; Edwards C K; Cheng J; Yang P; Wang Z; Liu C; Su X; Bluethmann H; Zhou T
Autoimmunity due to defective Nur77, Fas, and TNF-RI apoptosis.
Advances in experimental medicine and biology 1996;406():241-62.
1995: Mountz J D; Baker T J; Borcherding D R; Bluethmann H; Zhou T; Edwards C K
Increased susceptibility of fas mutant MRL-lpr/lpr mice to staphylococcal enterotoxin B-induced septic shock.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(10):4829-37.
1995: Mountz J M; Bradley L A; Modell J G; Alexander R W; Triana-Alexander M; Aaron L A; Stewart K E; Alarcón G S; Mountz J D
Fibromyalgia in women. Abnormalities of regional cerebral blood flow in the thalamus and the caudate nucleus are associated with low pain threshold levels.
Arthritis and rheumatism 1995;38(7):926-38.
1995: Cheng J; Liu C; Koopman W J; Mountz J D
Characterization of human Fas gene. Exon/intron organization and promoter region.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(3):1239-45.
1995: Mountz J D; Zhou T; Wu J; Wang W; Su X; Cheng J
Regulation of apoptosis in immune cells.
Journal of clinical immunology 1995;15(1):1-16.
1995: Mountz J D; Cheng J; Su X; Wu J; Zhou T
Autoimmunity, apoptosis defects and retroviruses.
Advances in experimental medicine and biology 1995;374():183-201.
1994: Mountz J D; Wu J; Cheng J; Zhou T
Autoimmune disease. A problem of defective apoptosis.
Arthritis and rheumatism 1994;37(10):1415-20.
1994: Wu J; Zhou T; Zhang J; He J; Gause W C; Mountz J D
Correction of accelerated autoimmune disease by early replacement of the mutated lpr gene with the normal Fas apoptosis gene in the T cells of transgenic MRL-lpr/lpr mice.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):2344-8.
1994: Mountz J D; Bluethmann H; Zhou T; Wu J
Defective clonal deletion and anergy induction in TCR transgenic lpr/lpr mice.
Seminars in immunology 1994;6(1):27-37.
1994: Mountz J D; Zhou T; Long R E; Bluethmann H; Koopman W J; Edwards C K
T cell influence on superantigen-induced arthritis in MRL-lpr/lpr mice.
Arthritis and rheumatism 1994;37(1):113-24.
1994: Mountz J D; Zhou T; Bluethmann H; Wu J; Edwards C K
Apoptosis defects analyzed in TcR transgenic and fas transgenic lpr mice.
International reviews of immunology 1994;11(4):321-42.
1993: Mountz J D; Gause W C
Murine models of autoimmune disease and Sjögren's syndrome.
Current opinion in rheumatology 1993;5(5):557-69.
1993: Mountz J D; Subler M A
Regulation of c-myb oncogene expression in immature and mature murine T cells.
Molecular immunology 1993;30(9):787-95.
1993: Zhou T; Bluethmann H; Eldridge J; Berry K; Mountz J D
Origin of CD4-CD8-B220+ T cells in MRL-lpr/lpr mice. Clues from a T cell receptor beta transgenic mouse.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(8 Pt 1):3651-67.
1992: Zhou T; Bluethmann H; Zhang J; Edwards C K; Mountz J D
Defective maintenance of T cell tolerance to a superantigen in MRL-lpr/lpr mice.
The Journal of experimental medicine 1992;176(4):1063-72.
1991: Owens J D; Finkelman F D; Mountz J D; Mushinski J F
Nonhomologous recombination at sites within the mouse JH-C delta locus accompanies C mu deletion and switch to immunoglobulin D secretion.
Molecular and cellular biology 1991;11(11):5660-70.
1991: Zhou T; Bluethmann H; Eldridge J; Brockhaus M; Berry K; Mountz J D
Abnormal thymocyte development and production of autoreactive T cells in T cell receptor transgenic autoimmune mice.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(2):466-74.
1990: Mountz J D; Zhou T; Eldridge J; Berry K; Blüthmann H
Transgenic rearranged T cell receptor gene inhibits lymphadenopathy and accumulation of CD4-CD8-B220+ T cells in lpr/lpr mice.
The Journal of experimental medicine 1990;172(6):1805-17.
1990: Mountz J D; Mushinski J F; Owens J D; Finkelman F D
The in vivo generation of murine IgD-secreting cells is accompanied by deletion of the C mu gene and occasional deletion of the gene for the C delta 1 domain.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(5):1583-91.
1989: Mountz J D; Steinberg A D
Studies of c-myb gene regulation in MRL-lpr/lpr mice. Identification of a 5' c-myb nuclear protein binding site and high levels of binding factors in nuclear extracts of lpr/lpr lymph node cells.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(1):328-35.
1988: Ansel J C; Luger T A; Lowry D; Perry P; Roop D R; Mountz J D
The expression and modulation of IL-1 alpha in murine keratinocytes.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(7):2274-8.

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