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Joachim Behlke

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David Schwefel; Burkhard Wiesner; B Sivanandam Arasu; Joachim Behlke; Jenny Eichhorst; Karl Köchert; Björn Lamprecht; Stephen F Marino; Stephan Mathas; Oliver Rocks; Eva Rosenbaum; Oliver Daumke
Structural insights into the mechanism of GTPase activation in the GIMAP family.
Janko Brand; Joachim Behlke; Alexey Kozlenkov; Liudmila Lapatsina; Gary R Lewin; Damir Omerbašić; Kate Poole; David Schwefel; Ewan St J Smith; Oliver Daumke
A stomatin dimer modulates the activity of acid-sensing ion channels.
Jennifer Hanna; Anja Schütz; Thomas Sommer; Franziska Zimmermann; Joachim Behlke; Udo Heinemann
Structural and biochemical basis of Yos9 protein dimerization and possible contribution to self-association of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation ubiquitin-ligase complex.

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2013: David Schwefel; Burkhard Wiesner; B Sivanandam Arasu; Joachim Behlke; Jenny Eichhorst; Karl Köchert; Björn Lamprecht; Stephen F Marino; Stephan Mathas; Oliver Rocks; Eva Rosenbaum; Oliver Daumke
Structural insights into the mechanism of GTPase activation in the GIMAP family.
Structure (London, England : 1993) 2013;21(4):550-9.
2012: Janko Brand; Joachim Behlke; Alexey Kozlenkov; Liudmila Lapatsina; Gary R Lewin; Damir Omerbašić; Kate Poole; David Schwefel; Ewan St J Smith; Oliver Daumke
A stomatin dimer modulates the activity of acid-sensing ion channels.
The EMBO journal 2012;31(17):3635-46.
2012: Jennifer Hanna; Anja Schütz; Thomas Sommer; Franziska Zimmermann; Joachim Behlke; Udo Heinemann
Structural and biochemical basis of Yos9 protein dimerization and possible contribution to self-association of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation ubiquitin-ligase complex.
The Journal of biological chemistry 2012;287(11):8633-40.
2011: Romy Siegert; Andreas Perrot; Sandro Keller; Joachim Behlke; Aleksandra Michalewska-Włudarczyk; Anna Wycisk; Michal Tendera; Ingo Morano; Cemil Ozcelik
A myomesin mutation associated with hypertrophic cardiomyopathy deteriorates dimerisation properties.
Biochemical and biophysical research communications 2011;405(3):473-9.
2011: Gisela Lättig-Tünnemann; Ingo Morano; Caroline Palm-Apergi; Manuel Prinz; Joachim Behlke; Henry D Herce; Daniel Hoffmann; M Cristina Cardoso
Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptides.
Nature communications 2011;2():453.
2010: David Schwefel; Chris Fröhlich; Jenny Eichhorst; Burkhard Wiesner; Joachim Behlke; L Aravind; Oliver Daumke
Structural basis of oligomerization in septin-like GTPase of immunity-associated protein 2 (GIMAP2).
Proceedings of the National Academy of Sciences of the United States of America 2010;107(47):20299-304.
2010: Daria Petzhold; Janine Lossie; Joachim Behlke; Sandro Keller; Hannelore Haase; Ingo Morano
Auto-inhibitory effects of an IQ motif on protein structure and function.
Biochemical and biophysical research communications 2010;396(4):939-43.
2010: Song Gao; Alexander von der Malsburg; Susann Paeschke; Joachim Behlke; Otto Haller; Georg Kochs; Oliver Daumke
Structural basis of oligomerization in the stalk region of dynamin-like MxA.
Nature 2010;465(7297):502-6.
2010: Joachim Behlke; Otto Ristau
Enhanced resolution of sedimentation coefficient distribution profiles by extrapolation to infinite time.
European biophysics journal : EBJ 2010;39(3):449-55.
2008: Jörg O Schulze; Claudia Quedenau; Yvette Roske; Thomas Adam; Herwig Schüler; Joachim Behlke; Andrew P Turnbull; Volker Sievert; Christoph Scheich; Uwe Mueller; Udo Heinemann; Konrad Büssow
Structural and functional characterization of human Iba proteins.
The FEBS journal 2008;275(18):4627-40.
2008: Maxim Rossmann; Robert Schultz-Heienbrok; Joachim Behlke; Natascha Remmel; Claudia Alings; Konrad Sandhoff; Wolfram Saenger; Timm Maier
Crystal structures of human saposins C andD: implications for lipid recognition and membrane interactions.
Structure (London, England : 1993) 2008;16(5):809-17.
2007: Joachim Behlke; Otto Ristau; Eva-Christina Müller; Frank Hannemann; Rita Bernhardt
Self-association of adrenodoxin studied by using analytical ultracentrifugation.
Biophysical chemistry 2007;125(1):159-65.
2006: Hannelore Haase; Gisela Dobbernack; Gisela Lättig-Tünnemann; Peter Karczewski; Cristina Cardoso; Daria Petzhold; Wolfgang-Peter Schlegel; Steffen Lutter; Petra Pierschalek; Joachim Behlke; Ingo Morano
Minigenes encoding N-terminal domains of human cardiac myosin light chain-1 improve heart function of transgenic rats.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(7):865-73.
2006: Olav M Andersen; Vanessa Schmidt; Robert Spoelgen; Jørgen Gliemann; Joachim Behlke; Denise Galatis; William J McKinstry; Michael W Parker; Colin L Masters; Bradley T Hyman; Roberto Cappai; Thomas E Willnow
Molecular dissection of the interaction between amyloid precursor protein and its neuronal trafficking receptor SorLA/LR11.
Biochemistry 2006;45(8):2618-28.
2005: Hannelore Haase; Julio Alvarez; Daria Petzhold; Anke Doller; Joachim Behlke; Jeanette Erdmann; Roland Hetzer; Vera Regitz-Zagrosek; Guy Vassort; Ingo Morano
Ahnak is critical for cardiac Ca(V)1.2 calcium channel function and its beta-adrenergic regulation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(14):1969-77.
2005: Joachim Behlke; Gertraud Koellner; Agnieszka Bzowska
Oligomeric structure of mammalian purine nucleoside phosphorylase in solution determined by analytical ultracentrifugation.
Zeitschrift für Naturforschung. C, Journal of biosciences 2005;60(11-12):927-31.
2005: Olav M Andersen; Juliane Reiche; Vanessa Schmidt; Michael Gotthardt; Robert Spoelgen; Joachim Behlke; Christine A F Von Arnim; Tilman Breiderhoff; Pernille Jansen; Xin Wu; Kelly R Bales; Roberto Cappai; Colin L Masters; Jørgen Gliemann; Elliott J Mufson; Bradley T Hyman; Steven M Paul; Anders Nykjaer; Thomas E Willnow
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(38):13461-6.
2005: Karin Welfle; Florencia Pratto; Rolf Misselwitz; Joachim Behlke; Juan C Alonso; Heinz Welfle
Role of the N-terminal region and of beta-sheet residue Thr29 on the activity of the omega2 global regulator from the broad-host range Streptococcus pyogenes plasmid pSM19035.
Biological chemistry 2005;386(9):881-94.
2005: Athina Zouni; Jan Kern; Joachim Frank; Thomas Hellweg; Joachim Behlke; Wolfram Saenger; Klaus-Dieter Irrgang
Size determination of cyanobacterial and higher plant photosystem II by gel permeation chromatography, light scattering, and ultracentrifugation.
Biochemistry 2005;44(11):4572-81.
2005: Andrew P Turnbull; Daniel Kümmel; Bianka Prinz; Caterina Holz; Jeffrey Schultchen; Christine Lang; Frank H Niesen; Klaus Peter Hofmann; Heinrich Delbrück; Joachim Behlke; Eva-Christina Müller; Ernst Jarosch; Thomas Sommer; Udo Heinemann
Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization.
The EMBO journal 2005;24(5):875-84.
2005: Babu A Manjasetty; Frank H Niesen; Christoph Scheich; Yvette Roske; Frank Goetz; Joachim Behlke; Volker Sievert; Udo Heinemann; Konrad Büssow
X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1).
BMC structural biology 2005;5():21.
2004: Babu A Manjasetty; Frank H Niesen; Heinrich Delbrück; Frank Götz; Volker Sievert; Konrad Büssow; Joachim Behlke; Udo Heinemann
X-ray structure of fumarylacetoacetate hydrolase family member Homo sapiens FLJ36880.
Biological chemistry 2004;385(10):935-42.
2003: Joachim Behlke; Otto Ristau
Sedimentation equilibrium: a valuable tool to study homologous and heterogeneous interactions of proteins or proteins and nucleic acids.
European biophysics journal : EBJ 2003;32(5):427-31.
2003: Alexey Chernogolov; Joachim Behlke; Wolf-Hagen Schunck; Ivar Roots; Dieter Schwarz
Human CYP1A1 allelic variants: baculovirus expression and purification, hydrodynamic, spectral, and catalytical properties and their potency in the formation of all-trans-retinoic acid.
Protein expression and purification 2003;28(2):259-69.
2003: Sebastian Tegethoff; Joachim Behlke; Claus Scheidereit
Tetrameric oligomerization of IkappaB kinase gamma (IKKgamma) is obligatory for IKK complex activity and NF-kappaB activation.
Molecular and cellular biology 2003;23(6):2029-41.
2003: Alexander Freiberg; Renato Morona; Luisa Van den Bosch; Christiane Jung; Joachim Behlke; Nils Carlin; Robert Seckler; Ulrich Baxa
The tailspike protein of Shigella phage Sf6. A structural homolog of Salmonella phage P22 tailspike protein without sequence similarity in the beta-helix domain.
The Journal of biological chemistry 2003;278(3):1542-8.
2002: Ana G Camacho; Rolf Misselwitz; Joachim Behlke; Silvia Ayora; Karin Welfle; Anton Meinhart; Beatriz Lara; Wolfram Saenger; Heinz Welfle; Juan C Alonso
In vitro and in vivo stability of the epsilon2zeta2 protein complex of the broad host-range Streptococcus pyogenes pSM19035 addiction system.
Biological chemistry 2002;383(11):1701-13.
2002: Merlind Mücke; Gerlinde Grelle; Joachim Behlke; Robert Kraft; Detlev H Krüger; Monika Reuter
EcoRII: a restriction enzyme evolving recombination functions?
The EMBO journal 2002;21(19):5262-8.
2002: Zsuzsanna Izsvák; Dheeraj Khare; Joachim Behlke; Udo Heinemann; Ronald H Plasterk; Zoltán Ivics
Involvement of a bifunctional, paired-like DNA-binding domain and a transpositional enhancer in Sleeping Beauty transposition.
The Journal of biological chemistry 2002;277(37):34581-8.
2002: Annette Hohaus; Veronika Person; Joachim Behlke; Jutta Schaper; Ingo Morano; Hannelore Haase
The carboxyl-terminal region of ahnak provides a link between cardiac L-type Ca2+ channels and the actin-based cytoskeleton.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(10):1205-16.
2002: Katrin Steinmetzer; Kornelia Kuhn; Joachim Behlke; Ralph Golbik; Sabine Brantl
Plasmid pIP501 encoded transcriptional repressor CopR: single amino acids involved in dimerization are also important for folding of the monomer.
Plasmid 2002;47(3):201-9.
2002: Katrin Steinmetzer; Joachim Behlke; Sabine Brantl; Mike Lorenz
CopR binds and bends its target DNA: a footprinting and fluorescence resonance energy transfer study.
Nucleic acids research 2002;30(9):2052-60.
2002: Joachim Behlke; Otto Ristau
A new approximate whole boundary solution of the Lamm differential equation for the analysis of sedimentation velocity experiments.
Biophysical chemistry 2002;95(1):59-68.
2001: Joachim Behlke; D Labudde; Otto Ristau
Self-association studies on the EphB2 receptor SAM domain using analytical ultracentrifugation.
European biophysics journal : EBJ 2001;30(6):411-5.
2001: Rolf Misselwitz; Ana Belén de la Hoz; Silvia Ayora; Karin Welfle; Joachim Behlke; K Murayama; Wolfram Saenger; Juan C Alonso; Heinz Welfle
Stability and DNA-binding properties of the omega regulator protein from the broad-host range Streptococcus pyogenes plasmid pSM19035.
FEBS letters 2001;505(3):436-40.
2001: thomas schwartz; Joachim Behlke; Ky Lowenhaupt; Udo Heinemann; A Rich
Structure of the DLM-1-Z-DNA complex reveals a conserved family of Z-DNA-binding proteins.
Nature structural biology 2001;8(9):761-5.
2001: M Wieske; Rainer Benndorf; Joachim Behlke; R Dölling; Gerlinde Grelle; H Bielka; Gudrun Lutsch
Defined sequence segments of the small heat shock proteins HSP25 and alphaB-crystallin inhibit actin polymerization.
European journal of biochemistry / FEBS 2001;268(7):2083-90.
2001: Ralph Golbik; Manfred Naumann; Albrecht Otto; E Müller; Joachim Behlke; Renate Reuter; Gerhard Hübner; Thomas M Kriegel
Regulation of phosphotransferase activity of hexokinase 2 from Saccharomyces cerevisiae by modification at serine-14.
Biochemistry 2001;40(4):1083-90.
2000: Merlind Mücke; R Lurz; Petra Mackeldanz; Joachim Behlke; Detlev H Krüger; Monika Reuter
Imaging DNA loops induced by restriction endonuclease EcoRII. A single amino acid substitution uncouples target recognition from cooperative DNA interaction and cleavage.
The Journal of biological chemistry 2000;275(39):30631-7.
2000: Joachim Behlke; Otto Ristau
Analysis of protein self-association under conditions of the thermodynamic non-ideality.
Biophysical chemistry 2000;87(1):1-13.
2000: Katrin Steinmetzer; Alexander Hillisch; Joachim Behlke; Sabine Brantl
Transcriptional repressor CopR: amino acids involved in forming the dimeric interface.
Proteins 2000;39(4):408-16.
2000: C Krafft; A Diehl; S Laettig; Joachim Behlke; Udo Heinemann; Cynthia L Pon; Claudio O Gualerzi; Heinz Welfle
Interaction of fMet-tRNA(fMet) with the C-terminal domain of translational initiation factor IF2 from Bacillus stearothermophilus.
FEBS letters 2000;471(2-3):128-32.
2000: Robyn A Lindner; John A Carver; Monika Ehrnsperger; Johannes Buchner; G Esposito; Joachim Behlke; Gudrun Lutsch; Alexey Kotlyarov; M Gaestel
Mouse Hsp25, a small shock protein. The role of its C-terminal extension in oligomerization and chaperone action.
European journal of biochemistry / FEBS 2000;267(7):1923-32.
2000: Katrin Steinmetzer; Alexander Hillisch; Joachim Behlke; Sabine Brantl
Transcriptional repressor CopR: structure model-based localization of the deoxyribonucleic acid binding motif.
Proteins 2000;38(4):393-406.
2000: Borries Demeler; Joachim Behlke; Otto Ristau
Molecular parameters from sedimentation velocity experiments: whole boundary fitting using approximate and numerical solutions of Lamm equation.
Methods in enzymology 2000;321():38-66.
1999: Markus Schade; Joachim Behlke; Ky Lowenhaupt; A Herbert; Alexander Rich; Hartmut Oschkinat
A 6 bp Z-DNA hairpin binds two Z alpha domains from the human RNA editing enzyme ADAR1.
FEBS letters 1999;458(1):27-31.
1999: Kai Hilpert; Joachim Behlke; Christa Scholz; Rolf Misselwitz; Jens Schneider-Mergener; Wolfgang Ernst Hoehne
Interaction of the capsid protein p24 (HIV-1) with sequence-derived peptides: influence on p24 dimerization.
Virology 1999;254(1):6-10.
1999: Joachim Behlke; Otto Ristau
Analysis of the thermodynamic non-ideality of proteins by sedimentation equilibrium experiments.
Biophysical chemistry 1999;76(1):13-23.
1998: Joachim Behlke; Otto Ristau
Gross conformation of dissolved angiotensin derived from sedimentation and diffusion coefficients.
Biochemical Society transactions 1998;26(4):758-61.
1998: Katrin Steinmetzer; Joachim Behlke; Sabine Brantl
Plasmid pIP501 encoded transcriptional repressor CopR binds to its target DNA as a dimer.
Journal of molecular biology 1998;283(3):595-603.
1998: Joachim Behlke; K Heidrich; Manfred Naumann; Eva-Christina Müller; Albrecht Otto; Renate Reuter; Thomas M Kriegel
Hexokinase 2 from Saccharomyces cerevisiae: regulation of oligomeric structure by in vivo phosphorylation at serine-14.
Biochemistry 1998;37(34):11989-95.
1998: Joachim Behlke; Otto Ristau
An improved approximate solution of the Lamm equation for the simultaneous estimation of sedimentation and diffusion coefficients from sedimentation velocity experiments.
Biophysical chemistry 1998;70(2):133-46.
1998: H J Schönfeld; Joachim Behlke
Molecular chaperones and their interactions investigated by analytical ultracentrifugation and other methodologies.
Methods in enzymology 1998;290():269-96.
1997: Joachim Behlke; Otto Ristau; H J Schönfeld
Nucleotide-dependent complex formation between the Escherichia coli chaperonins GroEL and GroES studied under equilibrium conditions.
Biochemistry 1997;36(17):5149-56.
1997: K Heidrich; Albrecht Otto; Joachim Behlke; J Rush; K W Wenzel; Thomas M Kriegel
Autophosphorylation-inactivation site of hexokinase 2 in Saccharomyces cerevisiae.
Biochemistry 1997;36(8):1960-4.
1997: Utz Dornberger; Joachim Behlke; Eckhard Birch-Hirschfeld; hartmut fritzsche
Hairpin-dimer equilibrium of a parallel-stranded DNA hairpin: formation of a four-stranded complex.
Nucleic acids research 1997;25(4):822-9.
1997: Joachim Behlke; Otto Ristau
Analysis of interacting biopolymer systems by analytical ultracentrifugation.
European biophysics journal : EBJ 1997;25(5-6):325-32.
1997: Joachim Behlke; Otto Ristau
Molecular mass determination by sedimentation velocity experiments and direct fitting of the concentration profiles.
Biophysical journal 1997;72(1):428-34.
1996: Joachim Behlke; Otto Ristau
Pyridoxal phosphate induced association reactions of adrenodoxin and adrenodoxin-reductase.
Biochemical and biophysical research communications 1996;219(2):663-7.
1995: S Monier; Robert Parton; F Vogel; Joachim Behlke; A Henske; Teymuras V Kurzchalia
VIP21-caveolin, a membrane protein constituent of the caveolar coat, oligomerizes in vivo and in vitro.
Molecular biology of the cell 1995;6(7):911-27.
1995: Christoph Grunau; R Dettmer; Joachim Behlke; Rita Bernhardt
Bovine adrenodoxin--a mitochondrial iron-sulphur protein--binds to chaperonin GroEL.
Biochemical and biophysical research communications 1995;210(3):1001-8.
1994: Rainer Benndorf; K Hayess; Sergey Ryazantsev; M Wieske; Joachim Behlke; Gudrun Lutsch
Phosphorylation and supramolecular organization of murine small heat shock protein HSP25 abolish its actin polymerization-inhibiting activity.
The Journal of biological chemistry 1994;269(32):20780-4.
1992: A Marg; R J Kuban; Joachim Behlke; R Dettmer; K Ruckpaul
Crystallization and X-ray examination of bovine adrenodoxin.
Journal of molecular biology 1992;227(3):945-7.
1991: Joachim Behlke; Gudrun Lutsch; Matthias Gaestel; H Bielka
Supramolecular structure of the recombinant murine small heat shock protein hsp25.
FEBS letters 1991;288(1-2):119-22.
1990: Thomas M Kriegel; Jörg Bär; Wolfgang Schellenberger; S König; Joachim Behlke; G Hübner; Gerhard Kopperschläger
Yeast phosphofructokinase: pre-steady-state and stationary kinetic studies on a cross-linked enzyme form.
Biomedica biochimica acta 1990;49(5):317-25.
1988: U A Bommer; Gudrun Lutsch; Joachim Behlke; J Stahl; N Nesytova; A Henske; H Bielka
Shape and location of eukaryotic initiation factor eIF-2 on the 40S ribosomal subunit of rat liver. Immunoelectron-microscopic and hydrodynamic investigations.
European journal of biochemistry / FEBS 1988;172(3):653-62.
1987: Thomas M Kriegel; Joachim Behlke; Gerhard Kopperschläger
Hydrodynamic studies on the quaternary structure of reacting yeast phosphofructokinase.
Biomedica biochimica acta 1987;46(5):349-55.
1986: Joachim Behlke; U A Bommer; Gudrun Lutsch; A Henske; H Bielka
Structure of initiation factor eIF-3 from rat liver. Hydrodynamic and electron microscopic investigations.
European journal of biochemistry / FEBS 1986;157(3):523-30.
1985: Gudrun Lutsch; Rainer Benndorf; P Westermann; Joachim Behlke; U A Bommer; H Bielka
On the structure of native small ribosomal subunits and initiation factor eIF-3 isolated from rat liver.
Biomedica biochimica acta 1985;44(2):K1-7.
1983: I Wendel; Joachim Behlke; G R Jänig
Hydrodynamic studies on the association of cytochrome P-450.
Biomedica biochimica acta 1983;42(6):633-40.
1983: I Wendel; Joachim Behlke; G R Jänig
Determination of the partial specific volume of cytochrome P-450 as a model of a membrane protein.
Biomedica biochimica acta 1983;42(6):623-31.
1982: A Makower; R Dettmer; T A Rapoport; S Knospe; Joachim Behlke; S Prehn; P Franke; G Etzold; S Rosenthal
Carp insulin: amino acid sequence, biological activity and structural properties.
European journal of biochemistry / FEBS 1982;122(2):339-45.
1980: Joachim Behlke; Heinz Welfle; I Wendel; H Bielka
Physicochemical studies of the 7 S complex of rat liver ribosomes and its components.
Acta biologica et medica Germanica 1980;39(1):33-40.