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Barbara Mueller

Research Profile

Living Beings

Anatomy

Tumor Cells, Cultured

Chemicals & Drugs

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Transplantation, Heterologous

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Publications

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Florence Schaffner; Naho Yokota; Michael Schaffer; G Mark Anderson; Tatiana Carneiro-Lobo; Charles T Esmon; Maki Kitano; Barbara M Mueller; Wolfram Ruf
Endothelial protein C receptor function in murine and human breast cancer development.
Florence Schaffner; Henri H Versteeg; Anja Schillert; Naho Yokota; Lars C Petersen; Barbara M Mueller; Wolfram Ruf
Cooperation of tissue factor cytoplasmic domain and PAR2 signaling in breast cancer development.
Henri H Versteeg; Florence Schaffner; Marjolein Kerver; Lesley G Ellies; Patricia Andrade-Gordon; Barbara M Mueller; Wolfram Ruf
Protease-activated receptor (PAR) 2, but not PAR1, signaling promotes the development of mammary adenocarcinoma in polyoma middle T mice.

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All Publications

2013: Florence Schaffner; Naho Yokota; Michael Schaffer; G Mark Anderson; Tatiana Carneiro-Lobo; Charles T Esmon; Maki Kitano; Barbara M Mueller; Wolfram Ruf
Endothelial protein C receptor function in murine and human breast cancer development.
PloS one 2013;8(4):e61071.
2010: Florence Schaffner; Henri H Versteeg; Anja Schillert; Naho Yokota; Lars C Petersen; Barbara M Mueller; Wolfram Ruf
Cooperation of tissue factor cytoplasmic domain and PAR2 signaling in breast cancer development.
Blood 2010;116(26):6106-13.
2008: Henri H Versteeg; Florence Schaffner; Marjolein Kerver; Lesley G Ellies; Patricia Andrade-Gordon; Barbara M Mueller; Wolfram Ruf
Protease-activated receptor (PAR) 2, but not PAR1, signaling promotes the development of mammary adenocarcinoma in polyoma middle T mice.
Cancer research 2008;68(17):7219-27.
2008: Henri H Versteeg; Florence Schaffner; Marjolein Kerver; Helle H Petersen; Jasimuddin Ahamed; Brunhilde Felding-Habermann; Yoshikazu Takada; Barbara M Mueller; Wolfram Ruf
Inhibition of tissue factor signaling suppresses tumor growth.
Blood 2008;111(1):190-9.
2007: Hannele Uusitalo-Jarvinen; Toru Kurokawa; Barbara M Mueller; Patricia Andrade-Gordon; Martin Friedlander; Wolfram Ruf
Role of protease activated receptor 1 and 2 signaling in hypoxia-induced angiogenesis.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(6):1456-62.
2006: Jasimuddin Ahamed; Henri H Versteeg; Marjolein Kerver; Vivien M Chen; Barbara M Mueller; Philip J Hogg; Wolfram Ruf
Disulfide isomerization switches tissue factor from coagulation to cell signaling.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(38):13932-7.
2006: Fang Guo; Sanjib Das; Barbara M Mueller; Carlos F Barbas; Richard A Lerner; Subhash C Sinha
Breaking the one antibody-one target axiom.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(29):11009-14.
2006: Yingmei Liu; Barbara M Mueller
Protease-activated receptor-2 regulates vascular endothelial growth factor expression in MDA-MB-231 cells via MAPK pathways.
Biochemical and biophysical research communications 2006;344(4):1263-70.
2006: Wolfram Ruf; Barbara M Mueller
Thrombin generation and the pathogenesis of cancer.
Seminars in thrombosis and hemostasis 2006;32 Suppl 1():61-8.
2005: Nadim Jessani; Sherry Niessen; Barbara M Mueller; Benjamin F Cravatt
Breast cancer cell lines grown in vivo: what goes in isn't always the same as what comes out.
Cell cycle (Georgetown, Tex.) 2005;4(2):253-5.
2004: Nadim Jessani; Mark Humphrey; W Hayes McDonald; Sherry Niessen; Kim Masuda; Beena Gangadharan; John R Yates; Barbara M Mueller; Benjamin F Cravatt
Carcinoma and stromal enzyme activity profiles associated with breast tumor growth in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(38):13756-61.
2004: Xiaoli Shi; Beena Gangadharan; Lawrence F Brass; Wolfram Ruf; Barbara M Mueller
Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis.
Molecular cancer research : MCR 2004;2(7):395-402.
2004: Mattias Belting; Michael I Dorrell; Staffan Sandgren; Edith Aguilar; Jasimuddin Ahamed; Andrea Dorfleutner; Peter Carmeliet; Barbara M Mueller; Martin Friedlander; Wolfram Ruf
Regulation of angiogenesis by tissue factor cytoplasmic domain signaling.
Nature medicine 2004;10(5):502-9.
2002: Matthias Riewald; Ramona J Petrovan; Aaron Donner; Barbara M Mueller; Wolfram Ruf
Activation of endothelial cell protease activated receptor 1 by the protein C pathway.
Science (New York, N.Y.) 2002;296(5574):1880-2.
2001: Brunhilde Felding-Habermann; Timothy E O'Toole; Jeffrey W Smith; Emilia Fransvea; Zaverio M Ruggeri; Mark H Ginsberg; Paul E Hughes; Nisar Pampori; Sanford J Shattil; Alan Saven; Barbara M Mueller
Integrin activation controls metastasis in human breast cancer.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1853-8.
2000: I Ott; Yohei Miyagi; K Miyazaki; M J Heeb; Barbara M Mueller; L V Rao; Wolfram Ruf
Reversible regulation of tissue factor-induced coagulation by glycosyl phosphatidylinositol-anchored tissue factor pathway inhibitor.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(3):874-82.
2000: Wolfram Ruf; EG Fischer; H Y Huang; Yohei Miyagi; I Ott; Matthias Riewald; Barbara M Mueller
Diverse functions of protease receptor tissue factor in inflammation and metastasis.
Immunologic research 2000;21(2-3):289-92.
1999: EG Fischer; Matthias Riewald; H Y Huang; Yohei Miyagi; Y Kubota; Barbara M Mueller; Wolfram Ruf
Tumor cell adhesion and migration supported by interaction of a receptor-protease complex with its inhibitor.
The Journal of clinical investigation 1999;104(9):1213-21.
1999: Wolfram Ruf; Barbara M Mueller
Tissue factor signaling.
Thrombosis and haemostasis 1999;82(2):175-82.
1999: M Yebra; L Goretzki; M Pfeifer; Barbara M Mueller
Urokinase-type plasminogen activator binding to its receptor stimulates tumor cell migration by enhancing integrin-mediated signal transduction.
Experimental cell research 1999;250(1):231-40.
1998: L Goretzki; Barbara M Mueller
Low-density-lipoprotein-receptor-related protein (LRP) interacts with a GTP-binding protein.
The Biochemical journal 1998;336 ( Pt 2)():381-6.
1998: Carrie Dolman; Barbara M Mueller; Holger N Lode; Rong Xiang; Stephen D Gillies; Ralph A Reisfeld
Suppression of human prostate carcinoma metastases in severe combined immunodeficient mice by interleukin 2 immunocytokine therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(10):2551-7.
1998: Barbara M Mueller; Wolfram Ruf
Requirement for binding of catalytically active factor VIIa in tissue factor-dependent experimental metastasis.
The Journal of clinical investigation 1998;101(7):1372-8.
1998: I Ott; EG Fischer; Yohei Miyagi; Barbara M Mueller; Wolfram Ruf
A role for tissue factor in cell adhesion and migration mediated by interaction with actin-binding protein 280.
The Journal of cell biology 1998;140(5):1241-53.
1997: L Goretzki; Barbara M Mueller
Receptor-mediated endocytosis of urokinase-type plasminogen activator is regulated by cAMP-dependent protein kinase.
Journal of cell science 1997;110 ( Pt 12)():1395-402.
1997: A Stahl; Barbara M Mueller
Melanoma cell migration on vitronectin: regulation by components of the plasminogen activation system.
International journal of cancer. Journal international du cancer 1997;71(1):116-22.
1996: M Yebra; Graham C Parry; Staffan Strömblad; Nigel Mackman; S Rosenberg; Barbara M Mueller; David A Cheresh
Requirement of receptor-bound urokinase-type plasminogen activator for integrin alphavbeta5-directed cell migration.
The Journal of biological chemistry 1996;271(46):29393-9.
1996: Wolfram Ruf; Barbara M Mueller
Tissue factor in cancer angiogenesis and metastasis.
Current opinion in hematology 1996;3(5):379-84.
1996: Barbara M Mueller
Different roles for plasminogen activators and metalloproteinases in melanoma metastasis.
Current topics in microbiology and immunology 1996;213 ( Pt 1)():65-80.
1995: E G Fischer; Wolfram Ruf; Barbara M Mueller
Tissue factor-initiated thrombin generation activates the signaling thrombin receptor on malignant melanoma cells.
Cancer research 1995;55(8):1629-32.
1995: A Stahl; Barbara M Mueller
The urokinase-type plasminogen activator receptor, a GPI-linked protein, is localized in caveolae.
The Journal of cell biology 1995;129(2):335-44.
1995: Barbara M Mueller; Y B Yu; Walter E Laug
Overexpression of plasminogen activator inhibitor 2 in human melanoma cells inhibits spontaneous metastasis in scid/scid mice.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(1):205-9.
1994: Anthony M P Montgomery; Barbara M Mueller; Ralph A Reisfeld; S M Taylor; Yves A DeClerck
Effect of tissue inhibitor of the matrix metalloproteinases-2 expression on the growth and spontaneous metastasis of a human melanoma cell line.
Cancer research 1994;54(20):5467-73.
1994: Helen Sabzevari; S D Gillies; Barbara M Mueller; J D Pancook; Ralph A Reisfeld
A recombinant antibody-interleukin 2 fusion protein suppresses growth of hepatic human neuroblastoma metastases in severe combined immunodeficiency mice.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(20):9626-30.
1994: A Stahl; Barbara M Mueller
Binding of urokinase to its receptor promotes migration and invasion of human melanoma cells in vitro.
Cancer research 1994;54(11):3066-71.
1994: Ralph A Reisfeld; Barbara M Mueller; R Handgretinger; Alice L Yu; S D Gillies
Potential of genetically engineered anti-ganglioside GD2 antibodies for cancer immunotherapy.
Progress in brain research 1994;101():201-12.
1993: M Naramura; S D Gillies; J Mendelsohn; R A Reisfeld; Barbara M Mueller
Mechanisms of cellular cytotoxicity mediated by a recombinant antibody-IL2 fusion protein against human melanoma cells.
Immunology letters 1993;39(1):91-9.
1993: M Naramura; S D Gillies; J Mendelsohn; R A Reisfeld; Barbara M Mueller
Therapeutic potential of chimeric and murine anti-(epidermal growth factor receptor) antibodies in a metastasis model for human melanoma.
Cancer immunology, immunotherapy : CII 1993;37(5):343-9.
1993: Anthony M P Montgomery; Y A De Clerck; KE Langley; Ralph A Reisfeld; Barbara M Mueller
Melanoma-mediated dissolution of extracellular matrix: contribution of urokinase-dependent and metalloproteinase-dependent proteolytic pathways.
Cancer research 1993;53(3):693-700.
1992: Barbara M Mueller; Ralph A Reisfeld; Thomas S Edgington; Wolfram Ruf
Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(24):11832-6.
1992: Brunhilde Felding-Habermann; Barbara M Mueller; C A Romerdahl; David A Cheresh
Involvement of integrin alpha V gene expression in human melanoma tumorigenicity.
The Journal of clinical investigation 1992;89(6):2018-22.
1992: Luraynne C Sanders; Brunhilde Felding-Habermann; Barbara M Mueller; David A Cheresh
Role of alpha V integrins and vitronectin in human melanoma cell growth.
Cold Spring Harbor symposia on quantitative biology 1992;57():233-40.
1991: Barbara M Mueller; C A Romerdahl; Jeffrey M. Trent; R A Reisfeld
Suppression of spontaneous melanoma metastasis in scid mice with an antibody to the epidermal growth factor receptor.
Cancer research 1991;51(8):2193-8.
1991: H Dorai; Barbara M Mueller; R A Reisfeld; S D Gillies
Aglycosylated chimeric mouse/human IgG1 antibody retains some effector function.
Hybridoma 1991;10(2):211-7.
1991: E Barker; Barbara M Mueller; R Handgretinger; M Herter; Alice L Yu; R A Reisfeld
Effect of a chimeric anti-ganglioside GD2 antibody on cell-mediated lysis of human neuroblastoma cells.
Cancer research 1991;51(1):144-9.
1990: Barbara M Mueller; W A Wrasidlo; R A Reisfeld
Antibody conjugates with morpholinodoxorubicin and acid-cleavable linkers.
Bioconjugate chemistry 1990;1(5):325-30.
1990: Barbara M Mueller; R A Reisfeld; S D Gillies
Serum half-life and tumor localization of a chimeric antibody deleted of the CH2 domain and directed against the disialoganglioside GD2.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(15):5702-5.
1990: Barbara M Mueller; C A Romerdahl; S D Gillies; R A Reisfeld
Enhancement of antibody-dependent cytotoxicity with a chimeric anti-GD2 antibody.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(4):1382-6.
1988: Barbara M Mueller; W A Wrasidlo; R A Reisfeld
Determination of the number of e-amino groups available for conjugation of effector molecules to monoclonal antibodies.
Hybridoma 1988;7(5):453-6.