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Jürgen Behrens

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
27
Birchmeier, Walter
5
Schneikert, Jean
4
Kühl, Michael
3
Lustig, Barbara
3
Kirchner, Thomas
3
Koch, Arend
3
Jerchow, Boris
3
Birchmeier, Walter
3
Asbrand, Christian
3
Sachs, Martin
3
Mierke, Claudia
3
Pietsch, Torsten
3
Waha, Andreas
3
Hadjihannas, Michel
2
Papadopoulos, Thomas

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Publications

TOP 3
Wacker Ingrid; Sachs Martin; Knaup Karl; Wiesener Michael; Weiske Jörg; Huber Otmar; Akçetin Ziya; Behrens Jürgen
Key role for activin B in cellular transformation after loss of the von Hippel-Lindau tumor suppressor.
Stemmer V; de Craene B; Berx G; Behrens J
Snail promotes Wnt target gene expression and interacts with beta-catenin.
Dehner Manuel; Hadjihannas Michel; Weiske Jörg; Huber Otmar; Behrens Jürgen
Wnt signaling inhibits Forkhead box O3a-induced transcription and apoptosis through up-regulation of serum- and glucocorticoid-inducible kinase 1.

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All Publications

2009: Wacker Ingrid; Sachs Martin; Knaup Karl; Wiesener Michael; Weiske Jörg; Huber Otmar; Akçetin Ziya; Behrens Jürgen
Key role for activin B in cellular transformation after loss of the von Hippel-Lindau tumor suppressor.
Molecular and cellular biology 2009;29(7):1707-18.
2008: Stemmer V; de Craene B; Berx G; Behrens J
Snail promotes Wnt target gene expression and interacts with beta-catenin.
Oncogene 2008;27(37):5075-80.
2008: Dehner Manuel; Hadjihannas Michel; Weiske Jörg; Huber Otmar; Behrens Jürgen
Wnt signaling inhibits Forkhead box O3a-induced transcription and apoptosis through up-regulation of serum- and glucocorticoid-inducible kinase 1.
The Journal of biological chemistry 2008;283(28):19201-10.
2008: Kohler Eva Maria; Derungs Adrian; Daum Gabriele; Behrens Jürgen; Schneikert Jean
Functional definition of the mutation cluster region of adenomatous polyposis coli in colorectal tumours.
Human molecular genetics 2008;17(13):1978-87.
2008: Croner Roland S; Förtsch Thomas; Brückl Wolfgang M; Rödel Franz; Rödel Claus; Papadopoulos Thomas; Brabletz Thomas; Kirchner Thomas; Sachs Martin; Behrens Jürgen; Klein-Hitpass Ludger; Stürzl Michael; Hohenberger Werner; Lausen Berthold
Molecular signature for lymphatic metastasis in colorectal carcinomas.
Annals of surgery 2008;247(5):803-10.
2008: Mierke Claudia Tanja; Zitterbart Daniel Paranhos; Kollmannsberger Philip; Raupach Carina; Schlötzer-Schrehardt Ursula; Goecke Tamme Weyert; Behrens Jürgen; Fabry Ben
Breakdown of the endothelial barrier function in tumor cell transmigration.
Biophysical journal 2008;94(7):2832-46.
2008: Spaderna Simone; Schmalhofer Otto; Wahlbuhl Mandy; Dimmler Arno; Bauer Katja; Sultan Aneesa; Hlubek Falk; Jung Andreas; Strand Dennis; Eger Andreas; Kirchner Thomas; Behrens Jürgen; Brabletz Thomas
The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer.
Cancer research 2008;68(2):537-44.
2008: Runz Steffen; Mierke Claudia T; Joumaa Safwan; Behrens Jürgen; Fabry Ben; Altevogt Peter
CD24 induces localization of beta1 integrin to lipid raft domains.
Biochemical and biophysical research communications 2008;365(1):35-41.
2007: Grohmann Annette; Tanneberger Kristina; Alzner Astrid; Schneikert Jean; Behrens Jürgen
AMER1 regulates the distribution of the tumor suppressor APC between microtubules and the plasma membrane.
Journal of cell science 2007;120(Pt 21):3738-47.
2007: Bauer Katja; Mierke Claudia; Behrens Jürgen
Expression profiling reveals genes associated with transendothelial migration of tumor cells: a functional role for alphavbeta3 integrin.
International journal of cancer. Journal international du cancer 2007;121(9):1910-8.
2007: Koch Arend; Hrychyk Aksana; Hartmann Wolfgang; Waha Anke; Mikeska Thomas; Waha Andreas; Schüller Ulrich; Sörensen Nils; Berthold Frank; Goodyer Cynthia G; Wiestler Otmar D; Birchmeier Walter; Behrens Jürgen; Pietsch Torsten
Mutations of the Wnt antagonist AXIN2 (Conductin) result in TCF-dependent transcription in medulloblastomas.
International journal of cancer. Journal international du cancer 2007;121(2):284-91.
2007: Schneikert Jean; Behrens Jürgen
The canonical Wnt signalling pathway and its APC partner in colon cancer development.
Gut 2007;56(3):417-25.
2007: Schneikert Jean; Grohmann Annette; Behrens Jürgen
Truncated APC regulates the transcriptional activity of beta-catenin in a cell cycle dependent manner.
Human molecular genetics 2007;16(2):199-209.
2006: Iden Sandra; Rehder Daniela; August Benjamin; Suzuki Atsushi; Wolburg-Buchholz Karen; Wolburg Hartwig; Ohno Shigeo; Behrens Jürgen; Vestweber Dietmar; Ebnet Klaus
A distinct PAR complex associates physically with VE-cadherin in vertebrate endothelial cells.
EMBO reports 2006;7(12):1239-46.
2006: Hadjihannas Michel V; Behrens Jürgen
CIN By WNT: growth pathways, mitotic control and chromosomal instability in cancer.
Cell cycle (Georgetown, Tex.) 2006;5(18):2077-81.
2006: Hadjihannas Michel V; Brückner Martina; Jerchow Boris; Birchmeier Walter; Dietmaier Wolfgang; Behrens Jürgen
Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(28):10747-52.
2006: Schneikert Jean; Behrens Jürgen
Truncated APC is required for cell proliferation and DNA replication.
International journal of cancer. Journal international du cancer 2006;119(1):74-9.
2006: Krieghoff Eva; Behrens Jürgen; Mayr Bernhard
Nucleo-cytoplasmic distribution of beta-catenin is regulated by retention.
Journal of cell science 2006;119(Pt 7):1453-63.
2006: Kuphal Felix; Behrens Jürgen
E-cadherin modulates Wnt-dependent transcription in colorectal cancer cells but does not alter Wnt-independent gene expression in fibroblasts.
Experimental cell research 2006;312(4):457-67.
2005: Behrens J
The role of the Wnt signalling pathway in colorectal tumorigenesis.
Biochemical Society transactions 2005;33(Pt 4):672-5.
2005: Schmitt-Graeff Annette; Ertelt-Heitzmann Viktoria; Allgaier Hans-Peter; Olschewski Manfred; Nitschke Roland; Haxelmans Sabine; Koelble Konrad; Behrens Jürgen; Blum Hubert Erich
Coordinated expression of cyclin D1 and LEF-1/TCF transcription factor is restricted to a subset of hepatocellular carcinoma.
Liver international : official journal of the International Association for the Study of the Liver 2005;25(4):839-47.
2005: Croner Roland S; Foertsch Thomas; Brueckl Wolfgang M; Guenther Klaus; Siebenhaar Renate; Stremmel Christian; Matzel Klaus E; Papadopoulos Thomas; Kirchner Thomas; Behrens Jürgen; Klein-Hitpass Ludger; Stuerzl Michael; Hohenberger Werner; Reingruber Bertram
Common denominator genes that distinguish colorectal carcinoma from normal mucosa.
International journal of colorectal disease 2005;20(4):353-62.
2004: Koch Arend; Weber Nina; Waha Andreas; Hartmann Wolfgang; Denkhaus Dorota; Behrens Jürgen; Birchmeier Walter; von Schweinitz Dietrich; Pietsch Torsten
Mutations and elevated transcriptional activity of conductin (AXIN2) in hepatoblastomas.
The Journal of pathology 2004;204(5):546-54.
2004: Krüger M; Behrens J; Länger F; Manns M P; Meier P N
Intramucosal adenocarcinoma of the appendix.
Endoscopy 2004;36(6):565; author reply 566.
2004: Behrens Jürgen; Lustig Barbara
The Wnt connection to tumorigenesis.
The International journal of developmental biology 2004;48(5-6):477-87.
2003: Oesterreich Steffi; Deng Wanleng; Jiang Shiming; Cui Xiaojiang; Ivanova Margarita; Schiff Rachel; Kang Kaiyan; Hadsell Darryl L; Behrens Jürgen; Lee Adrian V
Estrogen-mediated down-regulation of E-cadherin in breast cancer cells.
Cancer research 2003;63(17):5203-8.
2003: Harris E; Behrens J; Samson D; Rahemtulla A; Russell N H; Byrne J L
Use of thalidomide in patients with myeloma and renal failure may be associated with unexplained hyperkalaemia.
British journal of haematology 2003;122(1):160-1.
2003: Lustig B; Behrens J
The Wnt signaling pathway and its role in tumor development.
Journal of cancer research and clinical oncology 2003;129(4):199-221.
2003: Conway R M; Cursiefen C; Behrens J; Naumann G O H; Holbach L M
Biomolecular markers of malignancy in human uveal melanoma: the role of the cadherin-catenin complex and gene expression profiling.
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde 2003;217(1):68-75.
2002: Huelsken Joerg; Behrens Juergen
The Wnt signalling pathway.
Journal of cell science 2002;115(Pt 21):3977-8.
2002: Martin Bernd; Schneider Richard; Janetzky Stefanie; Waibler Zoe; Pandur Petra; Kühl Michael; Behrens Jürgen; von der Mark Klaus; Starzinski-Powitz Anna; Wixler Viktor
The LIM-only protein FHL2 interacts with beta-catenin and promotes differentiation of mouse myoblasts.
The Journal of cell biology 2002;159(1):113-22.
2002: Schwarz-Romond Thomas; Asbrand Christian; Bakkers Jeroen; Kühl Michael; Schaeffer Hans-Joerg; Huelsken Jörg; Behrens Jürgen; Hammerschmidt Matthias; Birchmeier Walter
The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling.
Genes & development 2002;16(16):2073-84.
2002: Swiercz Jakub M; Kuner Rohini; Behrens Jürgen; Offermanns Stefan
Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology.
Neuron 2002;35(1):51-63.
2002: Fujita Yasuyuki; Krause Gerd; Scheffner Martin; Zechner Dietmar; Leddy Hugo E Molina; Behrens Jürgen; Sommer Thomas; Birchmeier Walter
Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex.
Nature cell biology 2002;4(3):222-31.
2002: Lustig Barbara; Jerchow Boris; Sachs Martin; Weiler Sigrid; Pietsch Torsten; Karsten Uwe; van de Wetering Marc; Clevers Hans; Schlag Peter M; Birchmeier Walter; Behrens Jürgen
Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors.
Molecular and cellular biology 2002;22(4):1184-93.
2001: Dahmen R P; Koch A; Denkhaus D; Tonn J C; Sörensen N; Berthold F; Behrens J; Birchmeier W; Wiestler O D; Pietsch T
Deletions of AXIN1, a component of the WNT/wingless pathway, in sporadic medulloblastomas.
Cancer research 2001;61(19):7039-43.
2000: King M J; Behrens J; Rogers C; Flynn C; Greenwood D; Chambers K
Rapid flow cytometric test for the diagnosis of membrane cytoskeleton-associated haemolytic anaemia.
British journal of haematology 2000;111(3):924-33.
2000: Hlsken J; Behrens J
The Wnt signalling pathway.
Journal of cell science 2000;113 ( Pt 20)():3545.
2000: von Kries J P; Winbeck G; Asbrand C; Schwarz-Romond T; Sochnikova N; Dell'Oro A; Behrens J; Birchmeier W
Hot spots in beta-catenin for interactions with LEF-1, conductin and APC.
Nature structural biology 2000;7(9):800-7.
2000: Behrens J
Control of beta-catenin signaling in tumor development.
Annals of the New York Academy of Sciences 2000;910():21-33; discussion 33-5.
2000: Steinhusen U; Badock V; Bauer A; Behrens J; Wittman-Liebold B; Dörken B; Bommert K
Apoptosis-induced cleavage of beta-catenin by caspase-3 results in proteolytic fragments with reduced transactivation potential.
The Journal of biological chemistry 2000;275(21):16345-53.
2000: Behrens J
Cross-regulation of the Wnt signalling pathway: a role of MAP kinases.
Journal of cell science 2000;113 ( Pt 6)():911-9.
2000: Seidensticker M J; Behrens J
Biochemical interactions in the wnt pathway.
Biochimica et biophysica acta 2000;1495(2):168-82.
1999: Ghadimi B M; Behrens J; Hoffmann I; Haensch W; Birchmeier W; Schlag P M
Immunohistological analysis of E-cadherin, alpha-, beta- and gamma-catenin expression in colorectal cancer: implications for cell adhesion and signaling.
European journal of cancer (Oxford, England : 1990) 1999;35(1):60-5.
1999: Behrens J
Cadherins and catenins: role in signal transduction and tumor progression.
Cancer metastasis reviews 1999;18(1):15-30.
1998: Batsché E; Muchardt C; Behrens J; Hurst H C; Crémisi C
RB and c-Myc activate expression of the E-cadherin gene in epithelial cells through interaction with transcription factor AP-2.
Molecular and cellular biology 1998;18(7):3647-58.
1998: Behrens J; Jerchow B A; Würtele M; Grimm J; Asbrand C; Wirtz R; Kühl M; Wedlich D; Birchmeier W
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta.
Science (New York, N.Y.) 1998;280(5363):596-9.
1998: Dawson E B; Dawson R; Behrens J; DeVora M A; McGanity W J
Iron in prenatal multivitamin/multimineral supplements. Bioavailability.
The Journal of reproductive medicine 1998;43(2):133-40.
1997: Faraldo M L; Rodrigo I; Behrens J; Birchmeier W; Cano A
Analysis of the E-cadherin and P-cadherin promoters in murine keratinocyte cell lines from different stages of mouse skin carcinogenesis.
Molecular carcinogenesis 1997;20(1):33-47.
1997: Bataille V; Harland C C; Behrens J; Cook M G; Holden C A
Kikuchi disease (histiocytic necrotizing lymphadenitis) in association with HTLV1.
The British journal of dermatology 1997;136(4):610-2.
1997: Killick S; Mercieca J; Nandi A; Behrens J
Fludarabine-induced tumour lysis in low-grade non-Hodgkin's lymphoma.
Clinical and laboratory haematology 1997;19(1):79-80.
1997: Zschiesche W; Schönborn I; Behrens J; Herrenknecht K; Hartveit F; Lilleng P; Birchmeier W
Expression of E-cadherin and catenins in invasive mammary carcinomas.
Anticancer research 1997;17(1B):561-7.
1996: Weidner K M; Di Cesare S; Sachs M; Brinkmann V; Behrens J; Birchmeier W
Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis.
Nature 1996;384(6605):173-6.
1996: Behrens J; von Kries J P; Kühl M; Bruhn L; Wedlich D; Grosschedl R; Birchmeier W
Functional interaction of beta-catenin with the transcription factor LEF-1.
Nature 1996;382(6592):638-42.
1996: Hennig G; Löwrick O; Birchmeier W; Behrens J
Mechanisms identified in the transcriptional control of epithelial gene expression.
The Journal of biological chemistry 1996;271(1):595-602.
1996: Birchmeier W; Behrens J; Weidner K M; Hülsken J; Birchmeier C
Epithelial differentiation and the control of metastasis in carcinomas.
Current topics in microbiology and immunology 1996;213 ( Pt 2)():117-35.
1995: Takeda H; Nagafuchi A; Yonemura S; Tsukita S; Behrens J; Birchmeier W; Tsukita S
V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta catenin is not required for the shift.
The Journal of cell biology 1995;131(6 Pt 2):1839-47.
1995: Hennig G; Behrens J; Truss M; Frisch S; Reichmann E; Birchmeier W
Progression of carcinoma cells is associated with alterations in chromatin structure and factor binding at the E-cadherin promoter in vivo.
Oncogene 1995;11(3):475-84.
1995: Janes S L; Behrens J
Antituberculous therapy and acute liver failure.
Lancet 1995;345(8953):867.
1995: Kasper M; Behrens J; Schuh D; Müller M
Distribution of E-cadherin and Ep-CAM in the human lung during development and after injury.
Histochemistry and cell biology 1995;103(4):281-6.
1995: Plaschke-Schlütter A; Behrens J; Gherardi E; Birchmeier W
Characterization of the scatter factor/hepatocyte growth factor gene promoter. Positive and negative regulatory elements direct gene expression to mesenchymal cells.
The Journal of biological chemistry 1995;270(2):830-6.
1995: Birchmeier W; Hülsken J; Behrens J
E-cadherin as an invasion suppressor.
Ciba Foundation symposium 1995;189():124-36; discussion 136-41, 174-6.
1995: Birchmeier W; Hülsken J; Behrens J
Adherens junction proteins in tumour progression.
Cancer surveys 1995;24():129-40.
1994: Hülsken J; Birchmeier W; Behrens J
E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.
The Journal of cell biology 1994;127(6 Pt 2):2061-9.
1994: Hülsken J; Behrens J; Birchmeier W
Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection.
Current opinion in cell biology 1994;6(5):711-6.
1994: Kraus C; Liehr T; Hülsken J; Behrens J; Birchmeier W; Grzeschik K H; Ballhausen W G
Localization of the human beta-catenin gene (CTNNB1) to 3p21: a region implicated in tumor development.
Genomics 1994;23(1):272-4.
1994: Birchmeier W; Behrens J
Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness.
Biochimica et biophysica acta 1994;1198(1):11-26.
1994: Behrens J
Cadherins as determinants of tissue morphology and suppressors of invasion.
Acta anatomica 1994;149(3):165-9.
1994: Behrens J; Birchmeier W
Cell-cell adhesion in invasion and metastasis of carcinomas.
Cancer treatment and research 1994;71():251-66.
1994: Behrens J
Cell contacts, differentiation, and invasiveness of epithelial cells.
Invasion & metastasis 1994;14(1-6):61-70.
1993: Tooze J A; Marsh J C; Wickham N; Duke O L; Behrens J; Gordon-Smith E C
Response of aplastic anaemia and scleroderma to cyclosporin.
British journal of haematology 1993;85(4):829-31.
1993: Fenyves A M; Behrens J; Spanel-Borowski K
Cultured microvascular endothelial cells (MVEC) differ in cytoskeleton, expression of cadherins and fibronectin matrix. A study under the influence of interferon-gamma.
Journal of cell science 1993;106 ( Pt 3)():879-90.
1993: Birchmeier W; Weidner K M; Hülsken J; Behrens J
Molecular mechanisms leading to cell junction (cadherin) deficiency in invasive carcinomas.
Seminars in cancer biology 1993;4(4):231-9.
1993: Behrens J; Vakaet L; Friis R; Winterhager E; Van Roy F; Mareel M M; Birchmeier W
Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene.
The Journal of cell biology 1993;120(3):757-66.
1993: Behrens J
The role of cell adhesion molecules in cancer invasion and metastasis.
Breast cancer research and treatment 1993;24(3):175-84.
1993: Birchmeier W; Weidner K M; Behrens J
Molecular mechanisms leading to loss of differentiation and gain of invasiveness in epithelial cells.
Journal of cell science. Supplement 1993;17():159-64.
1992: Mercieca J; Matutes E; Moskovic E; MacLennan K; Matthey F; Costello C; Behrens J; Basu S; Roath S; Fairhead S
Massive abdominal lymphadenopathy in hairy cell leukaemia: a report of 12 cases.
British journal of haematology 1992;82(3):547-54.
1992: Behrens J; Frixen U; Schipper J; Weidner M; Birchmeier W
Cell adhesion in invasion and metastasis.
Seminars in cell biology 1992;3(3):169-78.
1991: Schipper J H; Frixen U H; Behrens J; Unger A; Jahnke K; Birchmeier W
E-cadherin expression in squamous cell carcinomas of head and neck: inverse correlation with tumor dedifferentiation and lymph node metastasis.
Cancer research 1991;51(23 Pt 1):6328-37.
1991: Behrens J; Löwrick O; Klein-Hitpass L; Birchmeier W
The E-cadherin promoter: functional analysis of a G.C-rich region and an epithelial cell-specific palindromic regulatory element.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(24):11495-9.
1991: Birchmeier W; Behrens J; Weidner K M; Frixen U H; Schipper J
Dominant and recessive genes involved in tumor cell invasion.
Current opinion in cell biology 1991;3(5):832-40.
1991: Mareel M M; Behrens J; Birchmeier W; De Bruyne G K; Vleminckx K; Hoogewijs A; Fiers W C; Van Roy F M
Down-regulation of E-cadherin expression in Madin Darby canine kidney (MDCK) cells inside tumors of nude mice.
International journal of cancer. Journal international du cancer 1991;47(6):922-8.
1991: Frixen U H; Behrens J; Sachs M; Eberle G; Voss B; Warda A; Löchner D; Birchmeier W
E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells.
The Journal of cell biology 1991;113(1):173-85.
1991: Behrens J; Weidner K M; Frixen U H; Schipper J H; Sachs M; Arakaki N; Daikuhara Y; Birchmeier W
The role of E-cadherin and scatter factor in tumor invasion and cell motility.
EXS 1991;59():109-26.
1990: Weidner K M; Behrens J; Vandekerckhove J; Birchmeier W
Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells.
The Journal of cell biology 1990;111(5 Pt 1):2097-108.
1989: Behrens J; Mareel M M; Van Roy F M; Birchmeier W
Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion.
The Journal of cell biology 1989;108(6):2435-47.
1987: Müller G; Behrens J; Nussbaumer U; Böhlen P; Birchmeier W
Inhibitory action of transforming growth factor beta on endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(16):5600-4.
1985: Behrens J; Birchmeier W; Goodman S L; Imhof B A
Dissociation of Madin-Darby canine kidney epithelial cells by the monoclonal antibody anti-arc-1: mechanistic aspects and identification of the antigen as a component related to uvomorulin.
The Journal of cell biology 1985;101(4):1307-15.

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