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Josephia Muindi

Research Profile

Chemicals & Drugs

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Publications

TOP 3
Nithya Ramnath; P J Stella; S Troeschel; A Adjei; D E Brenner; Kemp B Cease; S Daignault-Newton; G K Dy; V L Elingrod; C S Johnson; G P Kalemkerian; Josephia R Muindi; D L Trump
A phase I/II pharmacokinetic and pharmacogenomic study of calcitriol in combination with cisplatin and docetaxel in advanced non-small-cell lung cancer.
Manpreet K Chadha; Marwan G Fakih; Josephia R Muindi; Lili Tian; Terry Mashtare; Candace S Johnson; Donald Trump
Effect of 25-hydroxyvitamin D status on serological response to influenza vaccine in prostate cancer patients.
Kenneth M Rassnick; Josephia R Muindi; Candace S Johnson; Dennis B Bailey; Donald L Trump
Oral bioavailability of DN101, a concentrated formulation of calcitriol, in tumor-bearing dogs.

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All Publications

2013: Nithya Ramnath; P J Stella; S Troeschel; A Adjei; D E Brenner; Kemp B Cease; S Daignault-Newton; G K Dy; V L Elingrod; C S Johnson; G P Kalemkerian; Josephia R Muindi; D L Trump
A phase I/II pharmacokinetic and pharmacogenomic study of calcitriol in combination with cisplatin and docetaxel in advanced non-small-cell lung cancer.
Cancer chemotherapy and pharmacology 2013;71(5):1173-82.
2011: Manpreet K Chadha; Marwan G Fakih; Josephia R Muindi; Lili Tian; Terry Mashtare; Candace S Johnson; Donald Trump
Effect of 25-hydroxyvitamin D status on serological response to influenza vaccine in prostate cancer patients.
The Prostate 2011;71(4):368-72.
2011: Kenneth M Rassnick; Josephia R Muindi; Candace S Johnson; Dennis B Bailey; Donald L Trump
Oral bioavailability of DN101, a concentrated formulation of calcitriol, in tumor-bearing dogs.
Cancer chemotherapy and pharmacology 2011;67(1):165-71.
2010: Josephia R Muindi; Wei-Dong Yu; Yingyu Ma; Kristie L Engler; Rui-Xian Kong; Donald L Trump; Candace S Johnson
CYP24A1 inhibition enhances the antitumor activity of calcitriol.
Endocrinology 2010;151(9):4301-12.
2010: Wei-Dong Yu; Yingyu Ma; Geraldine Flynn; Josephia R Muindi; Rui-Xian Kong; Donald L Trump; Candace S Johnson
Calcitriol enhances gemcitabine anti-tumor activity in vitro and in vivo by promoting apoptosis in a human pancreatic carcinoma model system.
Cell cycle (Georgetown, Tex.) 2010;9(15):3022-9.
2010: Wei Luo; Adam R Karpf; Kristin K Deeb; Josephia R Muindi; Carl D Morrison; Candace S Johnson; Donald L Trump
Epigenetic regulation of vitamin D 24-hydroxylase/CYP24A1 in human prostate cancer.
Cancer research 2010;70(14):5953-62.
2010: Marwan G Fakih; Gerald Fetterly; Merrill J Egorin; Josephia R Muindi; Igor Espinoza-Delgado; James Zwiebel; Alan Litwin; Julianne L Holleran; Kangsheng Wang; Robert B Diasio
A phase I, pharmacokinetic, and pharmacodynamic study of two schedules of vorinostat in combination with 5-fluorouracil and leucovorin in patients with refractory solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(14):3786-94.
2009: Josephia R Muindi; Candace S Johnson; Donald L Trump; Renee Christy; Kristie L Engler; Marwan G Fakih
A phase I and pharmacokinetics study of intravenous calcitriol in combination with oral dexamethasone and gefitinib in patients with advanced solid tumors.
Cancer chemotherapy and pharmacology 2009;65(1):33-40.
2008: Kenneth M Rassnick; Josephia R Muindi; Candace S Johnson; Cheryl E Balkman; Nithya Ramnath; Wei-Dong Yu; Kristie L Engler; Rodney L Page; Donald L Trump
In vitro and in vivo evaluation of combined calcitriol and cisplatin in dogs with spontaneously occurring tumors.
Cancer chemotherapy and pharmacology 2008;62(5):881-91.
2008: Josephia R Muindi; Michael D Roth; Robert Wise; John E Connett; George T O'Connor; Joe W Ramsdell; Neil W Schluger; Marjorie Romkes; Robert A Branch; Frank C Sciurba
Pharmacokinetics and metabolism of all-trans- and 13-cis-retinoic acid in pulmonary emphysema patients.
Journal of clinical pharmacology 2008;48(1):96-107.
2007: Ivy Chung; Adam R Karpf; Josephia R Muindi; Jeffrey M Conroy; Norma J Nowak; Candace S Johnson; Donald L Trump
Epigenetic silencing of CYP24 in tumor-derived endothelial cells contributes to selective growth inhibition by calcitriol.
The Journal of biological chemistry 2007;282(12):8704-14.
2007: Josephia R Muindi; Alain Nganga; Kristie L Engler; Lionel J Coignet; Candace S Johnson; Donald L Trump
CYP24 splicing variants are associated with different patterns of constitutive and calcitriol-inducible CYP24 activity in human prostate cancer cell lines.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):334-7.
2007: Marwan G Fakih; Donald L Trump; Josephia R Muindi; Jennifer D Black; Ronald J Bernardi; Patrick J Creaven; James Schwartz; Michael G Brattain; Alan Hutson; Renee French; Candace S Johnson
A phase I pharmacokinetic and pharmacodynamic study of intravenous calcitriol in combination with oral gefitinib in patients with advanced solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(4):1216-23.
2007: Josephia R Muindi; Yibing Peng; John W Wilson; Candace S Johnson; Robert A Branch; Donald L Trump
Monocyte fructose 1,6-bisphosphatase and cytidine deaminase enzyme activities: potential pharmacodynamic measures of calcitriol effects in cancer patients.
Cancer chemotherapy and pharmacology 2007;59(1):97-104.
2006: Michael D Roth; John E Connett; Jeanine D'Armiento; Robert F Foronjy; Paul J Friedman; Jonathan G Goldin; Thomas A Louis; Jenny T Mao; Josephia R Muindi; George T O'Connor; Joe W Ramsdell; Andrew L Ries; Steven M Scharf; Neil W Schluger; Frank C Sciurba; Melissa A Skeans; Robert E Walter; Christine H Wendt; Robert Wise
Feasibility of retinoids for the treatment of emphysema study.
Chest 2006;130(5):1334-45.
2006: Donald L Trump; Josephia R Muindi; Marwan G Fakih; Wei-Dong Yu; Candace S Johnson
Vitamin D compounds: clinical development as cancer therapy and prevention agents.
Anticancer research 2006;26(4A):2551-6.
2006: Candace S Johnson; Josephia R Muindi; Pamela A Hershberger; Donald L Trump
The antitumor efficacy of calcitriol: preclinical studies.
Anticancer research 2006;26(4A):2543-9.
2006: Donald L Trump; Douglas M Potter; Josephia R Muindi; Adam Brufsky; Candace S Johnson
Phase II trial of high-dose, intermittent calcitriol (1,25 dihydroxyvitamin D3) and dexamethasone in androgen-independent prostate cancer.
Cancer 2006;106(10):2136-42.
2006: A Elefante; Josephia R Muindi; K West; Lauren M Dunford; S Abel; Pamela Paplham; Karen Brown; Theresa Hahn; Swaminathan Padmanabhan; Minoo Battiwalla; Philip L McCarthy
Long-term stability of a patient-convenient 1 mg/ml suspension of tacrolimus for accurate maintenance of stable therapeutic levels.
Bone marrow transplantation 2006;37(8):781-4.
2005: Josephia R Muindi; Douglas M Potter; Yibing Peng; Candace S Johnson; Donald L Trump
Pharmacokinetics of liquid calcitriol formulation in advanced solid tumor patients: comparison with caplet formulation.
Cancer chemotherapy and pharmacology 2005;56(5):492-6.
2004: Donald L Trump; Pamela A Hershberger; Ronald J Bernardi; Sharmilla Ahmed; Josephia R Muindi; Marwan G Fakih; Wei-Dong Yu; Candace S Johnson
Anti-tumor activity of calcitriol: pre-clinical and clinical studies.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):519-26.
2004: Josephia R Muindi; Ruth A Modzelewski; Yibing Peng; Donald L Trump; Candace S Johnson
Pharmacokinetics of 1alpha,25-dihydroxyvitamin D3 in normal mice after systemic exposure to effective and safe antitumor doses.
Oncology 2004;66(1):62-6.
2003: Josephia R Muindi; John W Wilson; Ying Peng; Mary Jo Capozolli; Candace S Johnson; Donald L Trump
A limited sampling method for the estimation of serum calcitriol area under the curve in cancer patients.
Journal of clinical pharmacology 2003;43(8):894-900.
2002: Josephia R Muindi; Yibing Peng; Douglas M Potter; Pamela A Hershberger; Jil S Tauch; Mary Jo Capozzoli; Merrill J Egorin; Candace S Johnson; Donald L Trump
Pharmacokinetics of high-dose oral calcitriol: results from a phase 1 trial of calcitriol and paclitaxel.
Clinical pharmacology and therapeutics 2002;72(6):648-59.
2002: Badrinath R Konety; George Somogyi; Ali Atan; Josephia R Muindi; Michael B Chancellor; Robert H Getzenberg
Evaluation of intraprostatic metabolism of 1,25-dihydroxyvitamin D(3) (calcitriol) using a microdialysis technique.
Urology 2002;59(6):947-52.
1999: David C Smith; Candace S Johnson; C C Freeman; Josephia R Muindi; John W Wilson; Donald L Trump
A Phase I trial of calcitriol (1,25-dihydroxycholecalciferol) in patients with advanced malignancy.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(6):1339-45.