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Eri Mukai

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Shimpei Fujimoto; Eri Mukai; Nobuya Inagaki
Role of endogenous ROS production in impaired metabolism-secretion coupling of diabetic pancreatic β cells.
Hiroyuki Fujimoto; Xibao Liu; Naoki Mochizuki; Eri Mukai; Teru Okitsu; Kentaro Toyoda; Shinji Uemoto; Xiaotong Zhuang; Nobuya Inagaki
Three-dimensional ex vivo imaging and analysis of intraportal islet transplants.
Eri Mukai; Shimpei Fujimoto; Nobuya Inagaki
[Severe hypoglycemia by combination therapy with dipeptidyl peptidase-4 (DPP-4) inhibitors and sulfonylureas].

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All Publications

2011: Shimpei Fujimoto; Eri Mukai; Nobuya Inagaki
Role of endogenous ROS production in impaired metabolism-secretion coupling of diabetic pancreatic β cells.
Progress in biophysics and molecular biology 2011;107(2):304-10.
2011: Hiroyuki Fujimoto; Xibao Liu; Naoki Mochizuki; Eri Mukai; Teru Okitsu; Kentaro Toyoda; Shinji Uemoto; Xiaotong Zhuang; Nobuya Inagaki
Three-dimensional ex vivo imaging and analysis of intraportal islet transplants.
Transplant international : official journal of the European Society for Organ Transplantation 2011;24(8):839-44.
2011: Eri Mukai; Shimpei Fujimoto; Nobuya Inagaki
[Severe hypoglycemia by combination therapy with dipeptidyl peptidase-4 (DPP-4) inhibitors and sulfonylureas].
Nihon rinsho. Japanese journal of clinical medicine 2011;69(5):907-11.
2011: Yuichi Nishi; Mayumi Sasaki; Hiroki Sato; Yuichi Sato; Yumiko Tahara; Shimpei Fujimoto; Eri Mukai; Yasuhiko Nakamura; Nobuya Inagaki
Role of mitochondrial phosphate carrier in metabolism-secretion coupling in rat insulinoma cell line INS-1.
The Biochemical journal 2011;435(2):421-30.
2011: Eri Mukai; Shimpei Fujimoto; Hiroki Sato; Chitose Oneyama; Rieko Kominato; Yuichi Sato; Mayumi Sasaki; Yuichi Nishi; Masato Okada; Nobuya Inagaki
Exendin-4 suppresses SRC activation and reactive oxygen species production in diabetic Goto-Kakizaki rat islets in an Epac-dependent manner.
Diabetes 2011;60(1):218-26.
2010: Y Fujita; M Hosokawa; Shimpei Fujimoto; Eri Mukai; A Abudukadier; A Obara; M Ogura; Yasuyuki Nakamura; K Toyoda; K Nagashima; Yutaka Seino; Nobuya Inagaki
Metformin suppresses hepatic gluconeogenesis and lowers fasting blood glucose levels through reactive nitrogen species in mice.
Diabetologia 2010;53(7):1472-81.
2010: Yukiko Kawasaki; S Harashima; M Sasaki; Eri Mukai; Yoshio Nakamura; Norio Harada; Kentaro Toyoda; Akihiro Hamasaki; S Yamane; Chizumi Yamada; Yuichiro Yamada; Yutaka Seino; Nobuya Inagaki
Exendin-4 protects pancreatic beta cells from the cytotoxic effect of rapamycin by inhibiting JNK and p38 phosphorylation.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2010;42(5):311-7.
2010: Makiko Shimodahira; Shimpei Fujimoto; Eri Mukai; Yasuhiko Nakamura; Yuichi Nishi; Mayumi Sasaki; Yuichi Sato; Hiroki Sato; Masaya Hosokawa; Kazuaki Nagashima; Yutaka Seino; Nobuya Inagaki
Rapamycin impairs metabolism-secretion coupling in rat pancreatic islets by suppressing carbohydrate metabolism.
The Journal of endocrinology 2010;204(1):37-46.
2009: Eri Mukai; Kentaro Toyoda; Hiroyuki Kimura; Hidekazu Kawashima; Hiroyuki Fujimoto; Masashi Ueda; Takashi Temma; Konomu Hirao; Kenji Nagakawa; Hideo Saji; Nobuya Inagaki
GLP-1 receptor antagonist as a potential probe for pancreatic beta-cell imaging.
Biochemical and biophysical research communications 2009;389(3):523-6.
2009: Xibao Liu; Norio Harada; Shunsuke Yamane; Lisa Kitajima; Saeko Uchida; Akihiro Hamasaki; Eri Mukai; Kentaro Toyoda; Chizumi Yamada; Yuichiro Yamada; Yutaka Seino; Nobuya Inagaki
Effects of long-term dipeptidyl peptidase-IV inhibition on body composition and glucose tolerance in high fat diet-fed mice.
Life sciences 2009;84(25-26):876-81.
2008: Rieko Kominato; Shimpei Fujimoto; Eri Mukai; Yasuyuki Nakamura; Koichiro Nabe; Makiko Shimodahira; Yuichi Nishi; Shogo Funakoshi; Yutaka Seino; Nobuya Inagaki
Src activation generates reactive oxygen species and impairs metabolism-secretion coupling in diabetic Goto-Kakizaki and ouabain-treated rat pancreatic islets.
Diabetologia 2008;51(7):1226-35.
2008: Yo Aramaki; Hirokazu Mitsuoka; Masako Toyohara; Toshikazu Jinnai; Kazushi Kanatani; Katsuyuki Nakajima; Eri Mukai; Yuichiro Yamada; Toru Kita; Nobuya Inagaki; Noriaki Kume
Lectin-like oxidized LDL receptor-1 (LOX-1) acts as a receptor for remnant-like lipoprotein particles (RLPs) and mediates RLP-induced migration of vascular smooth muscle cells.
Atherosclerosis 2008;198(2):272-9.
2008: Norio Harada; Yuichiro Yamada; Katsushi Tsukiyama; Chizumi Yamada; Yasuhiko Nakamura; Eri Mukai; Akihiro Hamasaki; Xibao Liu; Kentaro Toyoda; Yutaka Seino; Nobuya Inagaki
A novel GIP receptor splice variant influences GIP sensitivity of pancreatic beta-cells in obese mice.
American journal of physiology. Endocrinology and metabolism 2008;294(1):E61-8.
2007: Shimpei Fujimoto; Koichiro Nabe; Mihoko Takehiro; Makiko Shimodahira; Mariko Kajikawa; Tomomi Takeda; Eri Mukai; Nobuya Inagaki; Yutaka Seino
Impaired metabolism-secretion coupling in pancreatic beta-cells: role of determinants of mitochondrial ATP production.
Diabetes research and clinical practice 2007;77 Suppl 1():S2-10.
2007: Yusuke Shibata; Noriaki Kume; Hidenori Arai; Kazutaka Hayashida; Atsuko Inui-Hayashida; Manabu Minami; Eri Mukai; Masako Toyohara; Akiko Harauma; Toshinori Murayama; Toru Kita; Saburo Hara; Kaeko Kamei; Masayuki Yokode
Mulberry leaf aqueous fractions inhibit TNF-alpha-induced nuclear factor kappaB (NF-kappaB) activation and lectin-like oxidized LDL receptor-1 (LOX-1) expression in vascular endothelial cells.
Atherosclerosis 2007;193(1):20-7.
2006: Koichiro Nabe; Shimpei Fujimoto; Makiko Shimodahira; Rieko Kominato; Yuichi Nishi; Shogo Funakoshi; Eri Mukai; Yuichiro Yamada; Yutaka Seino; Nobuya Inagaki
Diphenylhydantoin suppresses glucose-induced insulin release by decreasing cytoplasmic H+ concentration in pancreatic islets.
Endocrinology 2006;147(6):2717-27.
2005: Dai Shimono; Shimpei Fujimoto; Eri Mukai; Mihoko Takehiro; Koichiro Nabe; Razvan Gheorghe Radu; Makiko Shimodahira; Rieko Kominato; Yo Aramaki; Yuichi Nishi; Shogo Funakoshi; Yuichiro Yamada; Yutaka Seino
ATP enhances exocytosis of insulin secretory granules in pancreatic islets under Ca2+-depleted condition.
Diabetes research and clinical practice 2005;69(3):216-23.
2005: Hiroyuki Ueno; Yuichiro Yamada; Rie Watanabe; Eri Mukai; Masaya Hosokawa; Akira Takahashi; Akihiro Hamasaki; Hideya Fujiwara; Shinya Toyokuni; Masahiro Yamaguchi; Jun Takeda; Yutaka Seino
Nestin-positive cells in adult pancreas express amylase and endocrine precursor Cells.
Pancreas 2005;31(2):126-31.
2005: Mihoko Takehiro; Shimpei Fujimoto; Makiko Shimodahira; Dai Shimono; Eri Mukai; Koichiro Nabe; Razvan Gheorghe Radu; Rieko Kominato; Yo Aramaki; Yutaka Seino; Yuichiro Yamada
Chronic exposure to beta-hydroxybutyrate inhibits glucose-induced insulin release from pancreatic islets by decreasing NADH contents.
American journal of physiology. Endocrinology and metabolism 2005;288(2):E372-80.
2005: Razvan Gheorghe Radu; Shimpei Fujimoto; Eri Mukai; Mihoko Takehiro; Dai Shimono; Koichiro Nabe; Makiko Shimodahira; Rieko Kominato; Yo Aramaki; Yuichi Nishi; Shogo Funakoshi; Yuichiro Yamada; Yutaka Seino
Tacrolimus suppresses glucose-induced insulin release from pancreatic islets by reducing glucokinase activity.
American journal of physiology. Endocrinology and metabolism 2005;288(2):E365-71.
2004: Kazutaka Hayashida; Noriaki Kume; Manabu Minami; Atsuko Inui-Hayashida; Eri Mukai; Masako Toyohara; Toru Kita
Peroxisome proliferator-activated receptor alpha ligands activate transcription of lectin-like oxidized low density lipoprotein receptor-1 gene through GC box motif.
Biochemical and biophysical research communications 2004;323(3):1116-23.
2004: Eri Mukai; Noriaki Kume; Kazutaka Hayashida; Manabu Minami; Yuichiro Yamada; Yutaka Seino; Toru Kita
Heparin-binding EGF-like growth factor induces expression of lectin-like oxidized LDL receptor-1 in vascular smooth muscle cells.
Atherosclerosis 2004;176(2):289-96.
2002: Mariko Kajikawa; Shimpei Fujimoto; Yoshiyuki Tsuura; Eri Mukai; Tomomi Takeda; Yoshiyuki Hamamoto; Mihoko Takehiro; Jun Fujita; Yuichiro Yamada; Yutaka Seino
Ouabain suppresses glucose-induced mitochondrial ATP production and insulin release by generating reactive oxygen species in pancreatic islets.
Diabetes 2002;51(8):2522-9.
2002: Koichiro Yasuda; Yoshimasa Okamoto; Kumiko Nunoi; Tetsuya Adachi; Nobuyuki Shihara; Akiko Tamon; Naoko Suzuki; Eri Mukai; Shimpei Fujimoto; Akira Oku; Kinsuke Tsuda; Yutaka Seino
Normalization of cytoplasmic calcium response in pancreatic beta-cells of spontaneously diabetic GK rat by the treatment with T-1095, a specific inhibitor of renal Na+-glucose co-transporters.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2002;34(4):217-21.
2002: Shimpei Fujimoto; Eri Mukai; Yoshiyuki Hamamoto; Tomomi Takeda; Mihoko Takehiro; Yuichiro Yamada; Yutaka Seino
Prior exposure to high glucose augments depolarization-induced insulin release by mitigating the decline of ATP level in rat islets.
Endocrinology 2002;143(1):213-21.
2001: Yoshiyuki Hamamoto; Yoshiyuki Tsuura; Shimpei Fujimoto; M Nagata; Tomomi Takeda; Eri Mukai; Jun Fujita; Yuichiro Yamada; Yutaka Seino
Recovery of function and mass of endogenous beta-cells in streptozotocin-induced diabetic rats treated with islet transplantation.
Biochemical and biophysical research communications 2001;287(1):104-9.
2001: ZP Shen; M Nishimura; Yoshiyuki Tsuura; Shimpei Fujimoto; Eri Mukai; Yuichiro Yamada; Yutaka Seino
Distinct effect of diazoxide on insulin secretion stimulated by protein kinase A and protein kinase C in rat pancreatic islets.
Diabetes research and clinical practice 2001;53(1):9-16.
2001: Tomomi Takeda; Yoshiyuki Tsuura; Jun Fujita; Shimpei Fujimoto; Eri Mukai; Mariko Kajikawa; Yoshiyuki Hamamoto; Makoto Kume; Yoshie Yamamoto; Yoshio Yamaoka; Yuichiro Yamada; Yutaka Seino
Heat shock restores insulin secretion after injury by nitric oxide by maintaining glucokinase activity in rat islets.
Biochemical and biophysical research communications 2001;284(1):20-5.
2001: A Shiraishi; Yuichiro Yamada; Yoshiyuki Tsuura; S Fijimoto; Katsushi Tsukiyama; Eri Mukai; Y Toyoda; I Miwa; Yutaka Seino
A novel glucokinase regulator in pancreatic beta cells: precursor of propionyl-CoA carboxylase beta subunit interacts with glucokinase and augments its activity.
The Journal of biological chemistry 2001;276(4):2325-8.
2000: Shimpei Fujimoto; Yoshiyuki Tsuura; H Ishida; K Tsuji; Eri Mukai; Mariko Kajikawa; Yoshiyuki Hamamoto; Tomomi Takeda; Yuichiro Yamada; Yutaka Seino
Augmentation of basal insulin release from rat islets by preexposure to a high concentration of glucose.
American journal of physiology. Endocrinology and metabolism 2000;279(4):E927-40.
2000: Eri Mukai; H Ishida; Shimpei Fujimoto; Mariko Kajikawa; Yasuo Okamoto; Jun Fujita; Yoshiyuki Hamamoto; Yoshiyuki Tsuura; Yuichiro Yamada; N Furukawa; T Ohta; Yutaka Seino
The insulinotropic mechanism of the novel hypoglycaemic agent JTT-608: direct enhancement of Ca(2+) efficacy and increase of Ca(2+) influx by phosphodiesterase inhibition.
British journal of pharmacology 2000;129(5):901-8.
1999: Mariko Kajikawa; H Ishida; Shimpei Fujimoto; Eri Mukai; M Nishimura; Jun Fujita; Yoshiyuki Tsuura; Yasuo Okamoto; A W Norman; Yutaka Seino
An insulinotropic effect of vitamin D analog with increasing intracellular Ca2+ concentration in pancreatic beta-cells through nongenomic signal transduction.
Endocrinology 1999;140(10):4706-12.
1999: Jun Fujita; Kinsuke Tsuda; Tomomi Takeda; L Yu; Shimpei Fujimoto; Mariko Kajikawa; M Nishimura; N Mizuno; Yoshiyuki Hamamoto; Eri Mukai; T Adachi; Yutaka Seino
Nisoldipine improves the impaired erythrocyte deformability correlating with elevated intracellular free calcium-ion concentration and poor glycaemic control in NIDDM.
British journal of clinical pharmacology 1999;47(5):499-506.
1998: H Ishida; Shigeaki Kato; M Nishimura; N Mizuno; Shimpei Fujimoto; Eri Mukai; Mariko Kajikawa; Yuichiro Yamada; H Odaka; Hiroki Ikeda; Yutaka Seino
Beneficial effect of long-term combined treatment with voglibose and pioglitazone on pancreatic islet function of genetically diabetic GK rats.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1998;30(11):673-8.
1998: Eri Mukai; H Ishida; Minoru Horie; Akinori Noma; Yutaka Seino; Makoto Takano
The antiarrhythmic agent cibenzoline inhibits KATP channels by binding to Kir6.2.
Biochemical and biophysical research communications 1998;251(2):477-81.
1998: Shimpei Fujimoto; H Ishida; Shigeaki Kato; Yasuo Okamoto; K Tsuji; N Mizuno; S Ueda; Eri Mukai; Yutaka Seino
The novel insulinotropic mechanism of pimobendan: direct enhancement of the exocytotic process of insulin secretory granules by increased Ca2+ sensitivity in beta-cells.
Endocrinology 1998;139(3):1133-40.
1998: M Nishimura; H Ishida; Yoshiyuki Tsuura; Shigeaki Kato; N Mizuno; Shimpei Fujimoto; Eri Mukai; Mariko Kajikawa; M Usami; Yutaka Seino
Necessity of endogenous GTP derived from glucose-6-phosphate for insulin secretion augmented by glucose under protein kinase A activation.
Biochemical and biophysical research communications 1998;243(1):253-7.
1998: Eri Mukai; H Ishida; Shinichi Kato; Yoshiyuki Tsuura; Shimpei Fujimoto; A Ishida-Takahashi; Minoru Horie; K Tsuda; Yutaka Seino
Metabolic inhibition impairs ATP-sensitive K+ channel block by sulfonylurea in pancreatic beta-cells.
The American journal of physiology 1998;274(1 Pt 1):E38-44.