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Frans Mulder

Research Profile

Procedures

Nuclear Magnetic Resonance, Biomolecular

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Chemicals & Drugs

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Publications

TOP 3
Trijntje J Pool; Nur Alia Oktaviani; Hironari Kamikubo; Mikio Kataoka; Frans A A Mulder
(1)H, (13)C, and (15)N resonance assignment of photoactive yellow protein.
Christina Avanti; Henderik W Frijlink; Wouter L J Hinrichs; Nur Alia Oktaviani; Frans A A Mulder
Aspartate buffer and divalent metal ions affect oxytocin in aqueous solution and protect it from degradation.
Kathleen Wood; François-Xavier Gallat; Michael Haertlein; Mathilde Lethier; Martine Moulin; Renee Otten; Lambert van Eijck; Auke J van Heel; Martin Weik; Frans A A Mulder
Protein surface and core dynamics show concerted hydration-dependent activation.

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All Publications

2013: Trijntje J Pool; Nur Alia Oktaviani; Hironari Kamikubo; Mikio Kataoka; Frans A A Mulder
(1)H, (13)C, and (15)N resonance assignment of photoactive yellow protein.
Biomolecular NMR assignments 2013;7(1):97-100.
2013: Christina Avanti; Henderik W Frijlink; Wouter L J Hinrichs; Nur Alia Oktaviani; Frans A A Mulder
Aspartate buffer and divalent metal ions affect oxytocin in aqueous solution and protect it from degradation.
International journal of pharmaceutics 2013;444(1-2):139-45.
2013: Kathleen Wood; François-Xavier Gallat; Michael Haertlein; Mathilde Lethier; Martine Moulin; Renee Otten; Lambert van Eijck; Auke J van Heel; Martin Weik; Frans A A Mulder
Protein surface and core dynamics show concerted hydration-dependent activation.
Angewandte Chemie (International ed. in English) 2013;52(2):665-8.
2012: Kamil Tamiola; Frans A A Mulder
Using NMR chemical shifts to calculate the propensity for structural order and disorder in proteins.
Biochemical Society transactions 2012;40(5):1014-20.
2012: Kathleen Wood; Klaas Dijkstra; Renee Otten; Aviv Paz; Ruud M Scheek; Israel Silman; Joel L Sussman; Frans A A Mulder
Backbone and side chain NMR assignments for the intrinsically disordered cytoplasmic domain of human neuroligin-3.
Biomolecular NMR assignments 2012;6(1):15-8.
2012: Nur Alia Oktaviani; Trijntje J Pool; Ruud M Scheek; Jelle Slager; Hironari Kamikubo; Mikio Kataoka; Frans A A Mulder
Comprehensive determination of protein tyrosine pKa values for photoactive yellow protein using indirect 13C NMR spectroscopy.
Biophysical journal 2012;102(3):579-86.
2011: Akira Karasawa; Frans A A Mulder; Renee Otten; Ronnie P-A Berntsson; Guus B Erkens; Gea K Schuurman-Wolters; Bert Poolman
Cystathionine β-synthase (CBS) domains 1 and 2 fulfill different roles in ionic strength sensing of the ATP-binding cassette (ABC) transporter OpuA.
The Journal of biological chemistry 2011;286(43):37280-91.
2011: Frans A A Mulder; Renee Otten; Ruud M Scheek
Origin and removal of mixed-phase artifacts in gradient sensitivity enhanced heteronuclear single quantum correlation spectra.
Journal of biomolecular NMR 2011;51(1-2):199-207.
2011: Kevin H Gardner; Anthony Mittermaier; Frans A A Mulder
Special issue as a tribute to Lewis E Kay on his 50th birthday.
Journal of biomolecular NMR 2011;51(1-2):3-207.
2011: Anne C Meinema; Frans A A Mulder; Renee Otten; Bert Poolman; Geert van den Bogaart; Rizqiya A Hapsari; Annemarie Kralt; Justyna K Laba; C Patrick Lusk; Liesbeth M Veenhoff
Long unfolded linkers facilitate membrane protein import through the nuclear pore complex.
Science (New York, N.Y.) 2011;333(6038):90-3.
2011: Kamil Tamiola; Frans A A Mulder
ncIDP-assign: a SPARKY extension for the effective NMR assignment of intrinsically disordered proteins.
Bioinformatics (Oxford, England) 2011;27(7):1039-40.
2011: Nur Alia Oktaviani; Renee Otten; Klaas Dijkstra; Ruud M Scheek; Eva Thulin; Mikael Akke; Frans A A Mulder
100% complete assignment of non-labile (1)H, (13)C, and (15)N signals for calcium-loaded Calbindin D(9k) P43G.
Biomolecular NMR assignments 2011;5(1):79-84.
2010: Kamil Tamiola; Burçin Acar; Frans A A Mulder
Sequence-specific random coil chemical shifts of intrinsically disordered proteins.
Journal of the American Chemical Society 2010;132(51):18000-3.
2010: Renee Otten; Janice Villali; Dorothee Kern; Frans A A Mulder
Probing microsecond time scale dynamics in proteins by methyl (1)H Carr-Purcell-Meiboom-Gill relaxation dispersion NMR measurements. Application to activation of the signaling protein NtrC(r).
Journal of the American Chemical Society 2010;132(47):17004-14.
2010: Stina Lindman; Mikael C Bauer; Mikael Lund; Carl Diehl; Frans A A Mulder; Mikael Akke; Sara Linse
pK(a) values for the unfolded state under native conditions explain the pH-dependent stability of PGB1.
Biophysical journal 2010;99(10):3365-73.
2010: Kathleen Wood; Douglas J Tobias; Brigitte Kessler; Frank Gabel; Dieter Oesterhelt; Frans A A Mulder; Giuseppe Zaccai; Martin Weik
The low-temperature inflection observed in neutron scattering measurements of proteins is due to methyl rotation: direct evidence using isotope labeling and molecular dynamics simulations.
Journal of the American Chemical Society 2010;132(14):4990-1.
2010: Renee Otten; Byron Chu; Karla D Krewulak; Hans J Vogel; Frans A A Mulder
Comprehensive and cost-effective NMR spectroscopy of methyl groups in large proteins.
Journal of the American Chemical Society 2010;132(9):2952-60.
2010: Frans A A Mulder; Michael Filatov
NMR chemical shift data and ab initio shielding calculations: emerging tools for protein structure determination.
Chemical Society reviews 2010;39(2):578-90.
2010: D Flemming Hansen; Philipp Neudecker; Pramodh Vallurupalli; Frans A A Mulder; Lewis E Kay
Determination of Leu side-chain conformations in excited protein states by NMR relaxation dispersion.
Journal of the American Chemical Society 2010;132(1):42-3.
2009: Renee Otten; Kathleen Wood; Frans A A Mulder
Comprehensive determination of (3)J (HNHalpha) for unfolded proteins using (13)C'-resolved spin-echo difference spectroscopy.
Journal of biomolecular NMR 2009;45(4):343-9.
2009: Frans A A Mulder
Leucine side-chain conformation and dynamics in proteins from 13C NMR chemical shifts.
Chembiochem : a European journal of chemical biology 2009;10(9):1477-9.
2008: Aviv Paz; Tzviya Zeev-Ben-Mordehai; Martin Lundqvist; Eilon Sherman; Efstratios Mylonas; Lev Weiner; Gilad Haran; Dmitri I Svergun; Frans A A Mulder; Joel Sussman; Israel Silman
Biophysical characterization of the unstructured cytoplasmic domain of the human neuronal adhesion protein neuroligin 3.
Biophysical journal 2008;95(4):1928-44.
2007: Ingemar André; Sara Linse; Frans A A Mulder
Residue-specific pKa determination of lysine and arginine side chains by indirect 15N and 13C NMR spectroscopy: application to apo calmodulin.
Journal of the American Chemical Society 2007;129(51):15805-13.
2007: Magnus Helgstrand; Chandra S Mandava; Frans A A Mulder; Anders Liljas; Suparna Sanyal; Mikael Akke
The ribosomal stalk binds to translation factors IF2, EF-Tu, EF-G and RF3 via a conserved region of the L12 C-terminal domain.
Journal of molecular biology 2007;365(2):468-79.
2007: Stina Lindman; Sara Linse; Frans A A Mulder; Ingemar André
pK(a) values for side-chain carboxyl groups of a PGB1 variant explain salt and pH-dependent stability.
Biophysical journal 2007;92(1):257-66.
2006: Stina Lindman; Sara Linse; Frans A A Mulder; Ingemar André
Electrostatic contributions to residue-specific protonation equilibria and proton binding capacitance for a small protein.
Biochemistry 2006;45(47):13993-4002.
2006: Ulrika Brath; Mikael Akke; Daiwen Yang; Lewis E Kay; Frans A A Mulder
Functional dynamics of human FKBP12 revealed by methyl 13C rotating frame relaxation dispersion NMR spectroscopy.
Journal of the American Chemical Society 2006;128(17):5718-27.
2005: Patrik Lundström; Frans A A Mulder; Mikael Akke
Correlated dynamics of consecutive residues reveal transient and cooperative unfolding of secondary structure in proteins.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(47):16984-9.
2004: Frans A A Mulder; Lamine Bouakaz; Anna Lundell; Musturi Venkataramana; Anders Liljas; Mikael Akke; Suparna Sanyal
Conformation and dynamics of ribosomal stalk protein L12 in solution and on the ribosome.
Biochemistry 2004;43(20):5930-6.
2002: Frans A A Mulder; Bin Hon; Anthony Mittermaier; Frederick W Dahlquist; Lewis E Kay
Slow internal dynamics in proteins: application of NMR relaxation dispersion spectroscopy to methyl groups in a cavity mutant of T4 lysozyme.
Journal of the American Chemical Society 2002;124(7):1443-51.
2002: Wing-Yiu Choy; Frans A A Mulder; Karin A Crowhurst; D Ranjith Muhandiram; Ian S Millett; Sebastian Doniach; Julie D Forman-Kay; Lewis E Kay
Distribution of molecular size within an unfolded state ensemble using small-angle X-ray scattering and pulse field gradient NMR techniques.
Journal of molecular biology 2002;316(1):101-12.
2001: Martin Tollinger; Nikolai R Skrynnikov; Frans A A Mulder; Julie D Forman-Kay; Lewis E Kay
Slow dynamics in folded and unfolded states of an SH3 domain.
Journal of the American Chemical Society 2001;123(46):11341-52.
2001: Frans A A Mulder; Anthony Mittermaier; Bin Hon; Frederick W Dahlquist; Lewis E Kay
Studying excited states of proteins by NMR spectroscopy.
Nature structural biology 2001;8(11):932-5.
2001: Ayeda Ayed; Frans A A Mulder; Gwan-Su Yi; Ying Lu; Lewis E Kay; Cheryl H Arrowsmith
Latent and active p53 are identical in conformation.
Nature structural biology 2001;8(9):756-60.
2001: Nikolai R Skrynnikov; Frans A A Mulder; Bin Hon; Frederick W Dahlquist; Lewis E Kay
Probing slow time scale dynamics at methyl-containing side chains in proteins by relaxation dispersion NMR measurements: application to methionine residues in a cavity mutant of T4 lysozyme.
Journal of the American Chemical Society 2001;123(19):4556-66.
2001: Frans A A Mulder; Nikolai R Skrynnikov; Bin Hon; Frederick W Dahlquist; Lewis E Kay
Measurement of slow (micros-ms) time scale dynamics in protein side chains by (15)N relaxation dispersion NMR spectroscopy: application to Asn and Gln residues in a cavity mutant of T4 lysozyme.
Journal of the American Chemical Society 2001;123(5):967-75.
2000: Frans A A Mulder; Bin Hon; D Ranjith Muhandiram; Frederick W Dahlquist; Lewis E Kay
Flexibility and ligand exchange in a buried cavity mutant of T4 lysozyme studied by multinuclear NMR.
Biochemistry 2000;39(41):12614-22.
2000: Frans A A Mulder; Ayeda Ayed; D Yang; Cheryl H Arrowsmith; Lewis E Kay
Assignment of 1H(N), 15N, 13C(alpha), 13CO and 13C(beta) resonances in a 67 kDa p53 dimer using 4D-TROSY NMR spectroscopy.
Journal of biomolecular NMR 2000;18(2):173-6.